FI108434B - Menetelmõ farmakologisesti vaikuttavien bentsimidatsolijohdannaisten valmistamiseksi - Google Patents

Menetelmõ farmakologisesti vaikuttavien bentsimidatsolijohdannaisten valmistamiseksi Download PDF

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Publication number
FI108434B
FI108434B FI911936A FI911936A FI108434B FI 108434 B FI108434 B FI 108434B FI 911936 A FI911936 A FI 911936A FI 911936 A FI911936 A FI 911936A FI 108434 B FI108434 B FI 108434B
Authority
FI
Finland
Prior art keywords
methyl
compound
formula
biphenyl
benzimidazole
Prior art date
Application number
FI911936A
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English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI911936A0 (fi
FI911936A (fi
Inventor
Kohei Nishikawa
Takehiko Naka
Takeshi Kato
Original Assignee
Takeda Chemical Industries Ltd
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Filing date
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27526589&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FI108434(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of FI911936A0 publication Critical patent/FI911936A0/fi
Publication of FI911936A publication Critical patent/FI911936A/fi
Priority to FI982761A priority Critical patent/FI114983B/fi
Application granted granted Critical
Publication of FI108434B publication Critical patent/FI108434B/fi

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/26—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/28—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/30—Nitrogen atoms not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Endocrinology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Steroid Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
FI911936A 1990-04-27 1991-04-22 Menetelmõ farmakologisesti vaikuttavien bentsimidatsolijohdannaisten valmistamiseksi FI108434B (fi)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FI982761A FI114983B (fi) 1990-04-27 1998-12-21 Menetelmä bentsimidatsoli-7-karboksylaatin C-tyyppiä olevan kiteen valmistamiseksi

Applications Claiming Priority (10)

Application Number Priority Date Filing Date Title
JP11314890 1990-04-27
JP11314890 1990-04-27
JP14194290 1990-05-30
JP14194290 1990-05-30
JP20866290 1990-08-06
JP20866290 1990-08-06
JP26457990 1990-10-01
JP26457990 1990-10-01
JP41367990 1990-12-24
JP41367990 1990-12-24

Publications (3)

Publication Number Publication Date
FI911936A0 FI911936A0 (fi) 1991-04-22
FI911936A FI911936A (fi) 1991-10-28
FI108434B true FI108434B (fi) 2002-01-31

Family

ID=27526589

Family Applications (2)

Application Number Title Priority Date Filing Date
FI911936A FI108434B (fi) 1990-04-27 1991-04-22 Menetelmõ farmakologisesti vaikuttavien bentsimidatsolijohdannaisten valmistamiseksi
FI982761A FI114983B (fi) 1990-04-27 1998-12-21 Menetelmä bentsimidatsoli-7-karboksylaatin C-tyyppiä olevan kiteen valmistamiseksi

Family Applications After (1)

Application Number Title Priority Date Filing Date
FI982761A FI114983B (fi) 1990-04-27 1998-12-21 Menetelmä bentsimidatsoli-7-karboksylaatin C-tyyppiä olevan kiteen valmistamiseksi

Country Status (22)

Country Link
US (4) US5196444A (da)
EP (2) EP0720982B1 (da)
JP (2) JP2514282B2 (da)
KR (1) KR100200541B1 (da)
CN (2) CN1048486C (da)
AT (2) ATE227709T1 (da)
CA (2) CA2204290C (da)
CY (1) CY2150B1 (da)
DE (3) DE19875004I2 (da)
DK (2) DK0459136T3 (da)
ES (2) ES2095266T3 (da)
FI (2) FI108434B (da)
GR (1) GR3022172T3 (da)
HK (1) HK1000803A1 (da)
HU (2) HU213266B (da)
IE (1) IE911317A1 (da)
LU (1) LU90224I2 (da)
LV (1) LV10258B (da)
NL (1) NL970044I2 (da)
NO (3) NO300923B1 (da)
NZ (1) NZ237949A (da)
PT (1) PT97451B (da)

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ES2095266T3 (es) 1997-02-16
FI911936A (fi) 1991-10-28
CA2040955A1 (en) 1991-10-28
NL970044I1 (nl) 1998-03-02
DE19875004I2 (de) 2002-03-28
CN1048486C (zh) 2000-01-19
NZ237949A (en) 1995-07-26
FI982761A (fi) 1998-12-21
CY2150B1 (en) 2002-08-23
PT97451B (pt) 1997-01-31
HU911347D0 (en) 1991-10-28
JPH0899960A (ja) 1996-04-16
PT97451A (pt) 1992-01-31
CN1147515A (zh) 1997-04-16
US5196444A (en) 1993-03-23
EP0720982A1 (en) 1996-07-10
NO911586L (no) 1991-10-28
CN1055927A (zh) 1991-11-06
US5401764A (en) 1995-03-28
DE69133149D1 (de) 2002-12-19
NO970195L (no) 1997-01-16
HUT57736A (en) 1991-12-30
KR910018359A (ko) 1991-11-30
CA2040955C (en) 1998-02-03
LV10258A (lv) 1994-10-20
JPH04364171A (ja) 1992-12-16
NO302752B1 (no) 1998-04-20
EP0720982B1 (en) 2002-11-13
DK0459136T3 (da) 1997-04-01
CN1058966C (zh) 2000-11-29
US5328919A (en) 1994-07-12
DK0720982T3 (da) 2003-03-17
ATE227709T1 (de) 2002-11-15
JP2853611B2 (ja) 1999-02-03

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