ES2638521T5 - Composiciones y métodos para anticuerpos y proteínas de fusión inmunomoduladores dirigidos contra dianas - Google Patents

Composiciones y métodos para anticuerpos y proteínas de fusión inmunomoduladores dirigidos contra dianas Download PDF

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Publication number
ES2638521T5
ES2638521T5 ES11751481T ES11751481T ES2638521T5 ES 2638521 T5 ES2638521 T5 ES 2638521T5 ES 11751481 T ES11751481 T ES 11751481T ES 11751481 T ES11751481 T ES 11751481T ES 2638521 T5 ES2638521 T5 ES 2638521T5
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molecule
seq
tumor
antibody
cells
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ES2638521T3 (es
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Atul Bedi
Rajani Ravi
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Johns Hopkins University
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Johns Hopkins University
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    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2827—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against B7 molecules, e.g. CD80, CD86
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    • A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
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    • A61K2039/572—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 cytotoxic response
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ES11751481T 2010-03-05 2011-03-04 Composiciones y métodos para anticuerpos y proteínas de fusión inmunomoduladores dirigidos contra dianas Active ES2638521T5 (es)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US31125510P 2010-03-05 2010-03-05
US311255P 2010-03-05
US201161435671P 2011-01-24 2011-01-24
US435671P 2011-01-24
PCT/US2011/027317 WO2011109789A2 (en) 2010-03-05 2011-03-04 Compositions and methods for targeted immunomodulatory antibodies and fusion proteins

Publications (2)

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ES2638521T3 ES2638521T3 (es) 2017-10-23
ES2638521T5 true ES2638521T5 (es) 2021-03-02

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US (7) US8993524B2 (OSRAM)
EP (3) EP3260470A1 (OSRAM)
JP (4) JP6066732B2 (OSRAM)
CA (3) CA2791383C (OSRAM)
DK (1) DK2542590T4 (OSRAM)
ES (1) ES2638521T5 (OSRAM)
IL (5) IL300733B1 (OSRAM)
PL (1) PL2542590T5 (OSRAM)
PT (1) PT2542590T (OSRAM)
WO (1) WO2011109789A2 (OSRAM)

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US7030219B2 (en) 2000-04-28 2006-04-18 Johns Hopkins University B7-DC, Dendritic cell co-stimulatory molecules
ES2643469T3 (es) 2006-04-07 2017-11-23 Aerpio Therapeutics, Inc. Anticuerpos que se unen a la proteína tirosina fosfatasa beta humana (HPTP-beta) y usos de los mismos
WO2009114085A2 (en) 2008-03-03 2009-09-17 The University Of Miami Allogeneic cancer cell-based immunotherapy
TWI729512B (zh) 2008-12-09 2021-06-01 美商建南德克公司 抗pd-l1抗體及其於增進t細胞功能之用途
CN102574924A (zh) 2009-09-03 2012-07-11 先灵公司 抗-gitr抗体
EP2504028A4 (en) * 2009-11-24 2014-04-09 Amplimmune Inc SIMULTANEOUS INHIBITION OF PD-L1 / PD-L2
JP6066732B2 (ja) * 2010-03-05 2017-01-25 ザ・ジョンズ・ホプキンス・ユニバーシティー 標的免疫調節抗体および融合タンパク質に基づく組成物および方法
CA3027071A1 (en) 2011-01-14 2013-07-19 The Regents Of The University Of California Therapeutic antibodies against ror-1 protein and methods for use of same
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