DK2542590T4 - Sammensætninger og fremgangsmåde til målrettede immunomodulatoriske antistof-fer og fusionproteiner - Google Patents

Sammensætninger og fremgangsmåde til målrettede immunomodulatoriske antistof-fer og fusionproteiner Download PDF

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DK2542590T4
DK2542590T4 DK11751481.0T DK11751481T DK2542590T4 DK 2542590 T4 DK2542590 T4 DK 2542590T4 DK 11751481 T DK11751481 T DK 11751481T DK 2542590 T4 DK2542590 T4 DK 2542590T4
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compositions
procedure
fusion proteins
immunomodulatory antibodies
targeted immunomodulatory
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DK11751481.0T
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DK2542590T3 (da
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Atul Bedi
Rajani Ravi
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Univ Johns Hopkins
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    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2827—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against B7 molecules, e.g. CD80, CD86
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
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    • C07K14/475—Growth factors; Growth regulators
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    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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    • C—CHEMISTRY; METALLURGY
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    • C07K16/2812—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD4
    • C—CHEMISTRY; METALLURGY
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    • C07K16/2815—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD8
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    • A61K2039/572—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 cytotoxic response
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    • C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
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    • C07K—PEPTIDES
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    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
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    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
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    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
DK11751481.0T 2010-03-05 2011-03-04 Sammensætninger og fremgangsmåde til målrettede immunomodulatoriske antistof-fer og fusionproteiner DK2542590T4 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US31125510P 2010-03-05 2010-03-05
US201161435671P 2011-01-24 2011-01-24
PCT/US2011/027317 WO2011109789A2 (en) 2010-03-05 2011-03-04 Compositions and methods for targeted immunomodulatory antibodies and fusion proteins

Publications (2)

Publication Number Publication Date
DK2542590T3 DK2542590T3 (da) 2017-08-28
DK2542590T4 true DK2542590T4 (da) 2020-07-13

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US (6) US8993524B2 (da)
EP (3) EP3260470A1 (da)
JP (4) JP6066732B2 (da)
CA (2) CA2791383C (da)
DK (1) DK2542590T4 (da)
ES (1) ES2638521T5 (da)
IL (4) IL300733A (da)
PL (1) PL2542590T5 (da)
PT (1) PT2542590T (da)
WO (1) WO2011109789A2 (da)

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CA2858350A1 (en) 2011-01-14 2013-07-19 The Regents Of The University Of California Therapeutic antibodies against ror-1 protein and methods for use of same
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