ES2337782T3 - Metodos para tratar o prevenir enfermedades autoinmunitarias con compuestos de 2,4-pirimidindiamina. - Google Patents

Metodos para tratar o prevenir enfermedades autoinmunitarias con compuestos de 2,4-pirimidindiamina. Download PDF

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Publication number
ES2337782T3
ES2337782T3 ES03784871T ES03784871T ES2337782T3 ES 2337782 T3 ES2337782 T3 ES 2337782T3 ES 03784871 T ES03784871 T ES 03784871T ES 03784871 T ES03784871 T ES 03784871T ES 2337782 T3 ES2337782 T3 ES 2337782T3
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Prior art keywords
quad
compound
group
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pyrimidinediamine
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Expired - Lifetime
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ES03784871T
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English (en)
Spanish (es)
Inventor
Rajinder Singh
Ankush Argade
Donald G. Payan
Jeffrey Clough
Holger Keim
Catherine Sylvain
Hui Li
Somasekhar Bhamidipati
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Rigel Pharmaceuticals Inc
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Rigel Pharmaceuticals Inc
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Application filed by Rigel Pharmaceuticals Inc filed Critical Rigel Pharmaceuticals Inc
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Publication of ES2337782T3 publication Critical patent/ES2337782T3/es
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
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  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Neurology (AREA)
  • Pulmonology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Dermatology (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Endocrinology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Psychiatry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Reproductive Health (AREA)
  • Hospice & Palliative Care (AREA)
  • Vascular Medicine (AREA)
  • Otolaryngology (AREA)
  • Transplantation (AREA)
ES03784871T 2002-07-29 2003-07-29 Metodos para tratar o prevenir enfermedades autoinmunitarias con compuestos de 2,4-pirimidindiamina. Expired - Lifetime ES2337782T3 (es)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US39967302P 2002-07-29 2002-07-29
US399673P 2002-07-29
US44394903P 2003-01-31 2003-01-31
US443949P 2003-01-31
US45233903P 2003-03-06 2003-03-06
US452339P 2003-03-06
US631029 2003-07-29
US10/631,029 US7517886B2 (en) 2002-07-29 2003-07-29 Methods of treating or preventing autoimmune diseases with 2,4-pyrimidinediamine compounds

Publications (1)

Publication Number Publication Date
ES2337782T3 true ES2337782T3 (es) 2010-04-29

Family

ID=31721742

Family Applications (2)

Application Number Title Priority Date Filing Date
ES10010732.5T Expired - Lifetime ES2445208T3 (es) 2002-07-29 2003-07-29 Compuestos de 2,4-pirimidindiamina para uso en métodos para tratar o prevenir enfermedades autoinmunitarias
ES03784871T Expired - Lifetime ES2337782T3 (es) 2002-07-29 2003-07-29 Metodos para tratar o prevenir enfermedades autoinmunitarias con compuestos de 2,4-pirimidindiamina.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES10010732.5T Expired - Lifetime ES2445208T3 (es) 2002-07-29 2003-07-29 Compuestos de 2,4-pirimidindiamina para uso en métodos para tratar o prevenir enfermedades autoinmunitarias

Country Status (24)

Country Link
US (5) US7517886B2 (enExample)
EP (1) EP1534286B1 (enExample)
JP (2) JP2006514989A (enExample)
CN (2) CN1678321A (enExample)
AT (1) ATE451104T1 (enExample)
AU (1) AU2003265336B8 (enExample)
BR (1) BR0313059B8 (enExample)
CA (1) CA2492325C (enExample)
CY (1) CY1110292T1 (enExample)
DE (1) DE60330466D1 (enExample)
DK (1) DK1534286T3 (enExample)
ES (2) ES2445208T3 (enExample)
HR (1) HRP20050089B1 (enExample)
IL (3) IL166241A (enExample)
IS (1) IS2923B (enExample)
MX (1) MXPA05001096A (enExample)
NO (1) NO332550B1 (enExample)
NZ (1) NZ537752A (enExample)
PL (1) PL216744B1 (enExample)
RS (1) RS51752B (enExample)
RU (1) RU2659777C9 (enExample)
SE (1) SE0500203L (enExample)
SG (1) SG176311A1 (enExample)
WO (1) WO2004014382A1 (enExample)

Families Citing this family (183)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI329105B (en) * 2002-02-01 2010-08-21 Rigel Pharmaceuticals Inc 2,4-pyrimidinediamine compounds and their uses
ATE451104T1 (de) * 2002-07-29 2009-12-15 Rigel Pharmaceuticals Inc Verfahren zur behandlung oder pruvention von autoimmunkrankheiten mit 2,4-pyrimidindiamin- verbindungen
EP1565446A1 (en) * 2002-11-28 2005-08-24 Schering Aktiengesellschaft Chk-, pdk- and akt-inhibitory pyrimidines, their production and use as pharmaceutical agents
UA80767C2 (en) * 2002-12-20 2007-10-25 Pfizer Prod Inc Pyrimidine derivatives for the treatment of abnormal cell growth
CL2004000306A1 (es) * 2003-02-20 2005-04-08 Tibotec Pharm Ltd Compuestos derivados de pirimidina sustituidas con indano; proceso para su preparacion; composicion farmaceutica que lo comprende; combinacion farmaceutica; y su uso para el tratamiento o profilaxis de una enfermedad infecciosa.
JP2007500179A (ja) * 2003-07-30 2007-01-11 サイクラセル・リミテッド キナーゼ阻害剤としての２−アミノフェニル−４−フェニルピリミジン
ES2421139T3 (es) 2003-07-30 2013-08-29 Rigel Pharmaceuticals, Inc. Compuestos de 2,4-pirimidindiamina para su uso en el tratamiento o la prevención de enfermedades autoinmunitarias
EP1663242B1 (en) * 2003-08-07 2011-04-27 Rigel Pharmaceuticals, Inc. 2,4-pyrimidinediamine compounds and uses as anti-proliferative agents
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