EA201492222A1 - Способы конструирования неаллореактивной и устойчивой к иммуносупрессии т-клетки для иммунотерапии - Google Patents

Способы конструирования неаллореактивной и устойчивой к иммуносупрессии т-клетки для иммунотерапии

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Publication number
EA201492222A1
EA201492222A1 EA201492222A EA201492222A EA201492222A1 EA 201492222 A1 EA201492222 A1 EA 201492222A1 EA 201492222 A EA201492222 A EA 201492222A EA 201492222 A EA201492222 A EA 201492222A EA 201492222 A1 EA201492222 A1 EA 201492222A1
Authority
EA
Eurasian Patent Office
Prior art keywords
cells
methods
immunotherapy
nonalloactive
immunosupression
Prior art date
Application number
EA201492222A
Other languages
English (en)
Russian (ru)
Inventor
Роман Галетто
Аньес Губль
Стефани Гросс
Сесиль Манниуи
Лоран Пуаро
Эндрю Шаренберг
Джулианна Смит
Original Assignee
Селлектис
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=48579464&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EA201492222(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Селлектис filed Critical Селлектис
Publication of EA201492222A1 publication Critical patent/EA201492222A1/ru

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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0636—T lymphocytes
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    • A61K40/10—Cellular immunotherapy characterised by the cell type used
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    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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EA201492222A 2012-05-25 2013-05-13 Способы конструирования неаллореактивной и устойчивой к иммуносупрессии т-клетки для иммунотерапии EA201492222A1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261651933P 2012-05-25 2012-05-25
US201261696612P 2012-09-04 2012-09-04
PCT/US2013/040755 WO2013176915A1 (en) 2012-05-25 2013-05-13 Methods for engineering allogeneic and immunosuppressive resistant t cell for immunotherapy

Publications (1)

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EA201492222A1 true EA201492222A1 (ru) 2015-05-29

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EA201492222A EA201492222A1 (ru) 2012-05-25 2013-05-13 Способы конструирования неаллореактивной и устойчивой к иммуносупрессии т-клетки для иммунотерапии

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US (15) US11603539B2 (enExample)
EP (7) EP2855667B1 (enExample)
JP (5) JP6463672B2 (enExample)
KR (2) KR102437522B1 (enExample)
CN (3) CN104718284A (enExample)
AR (2) AR096274A1 (enExample)
AU (5) AU2013266733B2 (enExample)
BR (1) BR112014029417B1 (enExample)
CA (3) CA3133545C (enExample)
DK (2) DK3473707T3 (enExample)
EA (1) EA201492222A1 (enExample)
ES (2) ES3015120T3 (enExample)
HK (1) HK1245321A1 (enExample)
HU (2) HUE070380T2 (enExample)
IN (1) IN2014DN10991A (enExample)
MA (1) MA37681B2 (enExample)
MX (1) MX370265B (enExample)
MY (1) MY180127A (enExample)
NZ (1) NZ703281A (enExample)
PL (2) PL2855667T3 (enExample)
PT (2) PT2855667T (enExample)
SG (2) SG10201806573TA (enExample)
UA (1) UA118652C2 (enExample)
WO (2) WO2013176915A1 (enExample)
ZA (1) ZA201409536B (enExample)

Cited By (4)

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US11365226B2 (en) 2016-09-08 2022-06-21 2Seventy Bio, Inc. PD-1 homing endonuclease variants, compositions, and methods of use
RU2781083C2 (ru) * 2016-09-08 2022-10-05 2сэвэнти био, Инк. Варианты, композиции и методы применения хоминг-эндонуклеазы pd-1
US12404500B2 (en) 2018-12-10 2025-09-02 Novo Nordisk A/S Homing endonuclease variants
US12577547B2 (en) 2018-12-10 2026-03-17 Regeneron Pharmaceuticals, Inc. PDCD-1 homing endonuclease variants

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US9273283B2 (en) * 2009-10-29 2016-03-01 The Trustees Of Dartmouth College Method of producing T cell receptor-deficient T cells expressing a chimeric receptor
WO2013066438A2 (en) 2011-07-22 2013-05-10 President And Fellows Of Harvard College Evaluation and improvement of nuclease cleavage specificity
US9950282B2 (en) 2012-03-15 2018-04-24 Flodesign Sonics, Inc. Electronic configuration and control for acoustic standing wave generation
US10967298B2 (en) 2012-03-15 2021-04-06 Flodesign Sonics, Inc. Driver and control for variable impedence load
US10704021B2 (en) 2012-03-15 2020-07-07 Flodesign Sonics, Inc. Acoustic perfusion devices
US9458450B2 (en) 2012-03-15 2016-10-04 Flodesign Sonics, Inc. Acoustophoretic separation technology using multi-dimensional standing waves
US20150017136A1 (en) * 2013-07-15 2015-01-15 Cellectis Methods for engineering allogeneic and highly active t cell for immunotherapy
SG10201806573TA (en) 2012-05-25 2018-09-27 Cellectis Methods for engineering allogeneic and immunosuppressive resistant t cell for immunotherapy
WO2014059173A2 (en) * 2012-10-10 2014-04-17 Sangamo Biosciences, Inc. T cell modifying compounds and uses thereof
EP2934532B1 (en) 2012-12-20 2019-10-23 Purdue Research Foundation Chimeric antigen receptor-expressing t cells as anti-cancer therapeutics
IL305629A (en) 2013-02-15 2023-11-01 Univ California Chimeric antigen receptor and methods of using it
US9499855B2 (en) 2013-03-14 2016-11-22 Elwha Llc Compositions, methods, and computer systems related to making and administering modified T cells
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