SG11202101773WA - Anti-mesothelin chimeric antigen receptor (car) constructs and uses thereof - Google Patents

Anti-mesothelin chimeric antigen receptor (car) constructs and uses thereof

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Publication number
SG11202101773WA
SG11202101773WA SG11202101773WA SG11202101773WA SG11202101773WA SG 11202101773W A SG11202101773W A SG 11202101773WA SG 11202101773W A SG11202101773W A SG 11202101773WA SG 11202101773W A SG11202101773W A SG 11202101773WA SG 11202101773W A SG11202101773W A SG 11202101773WA
Authority
SG
Singapore
Prior art keywords
constructs
car
antigen receptor
chimeric antigen
mesothelin chimeric
Prior art date
Application number
SG11202101773WA
Inventor
Qing Dai
Jian Liu
Shuai Yang
Kun Jiang
Yuanyuan Peng
Chen Hu
Shu Wu
Original Assignee
Nanjing Legend Biotech Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nanjing Legend Biotech Co Ltd filed Critical Nanjing Legend Biotech Co Ltd
Publication of SG11202101773WA publication Critical patent/SG11202101773WA/en

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    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
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    • C07K16/2869—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against hormone receptors
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SG11202101773WA 2018-08-29 2019-08-29 Anti-mesothelin chimeric antigen receptor (car) constructs and uses thereof SG11202101773WA (en)

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CN2018103050 2018-08-29
CN2019083918 2019-04-23
PCT/CN2019/103215 WO2020043152A1 (en) 2018-08-29 2019-08-29 Anti-mesothelin chimeric antigen receptor (car) constructs and uses thereof

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US (1) US11932698B2 (en)
EP (1) EP3844282A4 (en)
JP (1) JP7490915B2 (en)
KR (1) KR20210053318A (en)
CN (1) CN112639102B (en)
AU (1) AU2019327913A1 (en)
CA (1) CA3111087A1 (en)
IL (1) IL281098A (en)
SG (1) SG11202101773WA (en)
TW (1) TW202024330A (en)
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FI3298033T4 (en) 2015-05-18 2023-09-22 Tcr2 Therapeutics Inc Compositions and medical uses for tcr reprogramming using fusion proteins
EP3573464A4 (en) * 2017-01-26 2020-12-30 Sangamo Therapeutics, Inc. B-cell engineering
WO2021226289A2 (en) * 2020-05-05 2021-11-11 TCR2 Therapeutics Inc. Compositions and methods for tcr reprogramming using cd70 specific fusion proteins
GB202006820D0 (en) * 2020-05-07 2020-06-24 Autolus Ltd Cell
GB202008688D0 (en) * 2020-06-09 2020-07-22 Cancer Research Tech Ltd Chimeric antigen receptor cell
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