DK1124961T3 - Trombopoietiske forbindelser - Google Patents

Trombopoietiske forbindelser

Info

Publication number
DK1124961T3
DK1124961T3 DK99970998T DK99970998T DK1124961T3 DK 1124961 T3 DK1124961 T3 DK 1124961T3 DK 99970998 T DK99970998 T DK 99970998T DK 99970998 T DK99970998 T DK 99970998T DK 1124961 T3 DK1124961 T3 DK 1124961T3
Authority
DK
Denmark
Prior art keywords
thrombopoietic compounds
thrombopoietic
compounds
Prior art date
Application number
DK99970998T
Other languages
Danish (da)
English (en)
Inventor
Chuan-Fa Liu
Ulrich Feige
Janet Cheetham
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Inc filed Critical Amgen Inc
Application granted granted Critical
Publication of DK1124961T3 publication Critical patent/DK1124961T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/524—Thrombopoietin, i.e. C-MPL ligand
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
    • C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DK99970998T 1998-10-23 1999-10-22 Trombopoietiske forbindelser DK1124961T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10534898P 1998-10-23 1998-10-23
PCT/US1999/024834 WO2000024770A2 (en) 1998-10-23 1999-10-22 Dimeric thrombopoietin peptide mimetics binding to mp1 receptor and having thrombopoietic activity

Publications (1)

Publication Number Publication Date
DK1124961T3 true DK1124961T3 (da) 2007-04-10

Family

ID=22305310

Family Applications (3)

Application Number Title Priority Date Filing Date
DK10011689T DK2319928T3 (da) 1998-10-23 1999-10-22 Dimere trombopoietiske peptidomimetika, der binder til MPL-receptor og har trombopoietisk aktivitet
DK06022333T DK1783222T3 (da) 1998-10-23 1999-10-22 Dimere trombopoietiske peptidomimetika, der binder til MPL-receptor og har trombopoietisk aktivitet
DK99970998T DK1124961T3 (da) 1998-10-23 1999-10-22 Trombopoietiske forbindelser

Family Applications Before (2)

Application Number Title Priority Date Filing Date
DK10011689T DK2319928T3 (da) 1998-10-23 1999-10-22 Dimere trombopoietiske peptidomimetika, der binder til MPL-receptor og har trombopoietisk aktivitet
DK06022333T DK1783222T3 (da) 1998-10-23 1999-10-22 Dimere trombopoietiske peptidomimetika, der binder til MPL-receptor og har trombopoietisk aktivitet

Country Status (36)

Country Link
US (8) US6835809B1 (el)
EP (3) EP1783222B1 (el)
JP (2) JP3820105B2 (el)
KR (1) KR100719202B1 (el)
CN (2) CN1250721C (el)
AR (1) AR020934A1 (el)
AT (1) ATE348163T1 (el)
AU (1) AU773891C (el)
BG (3) BG110221A (el)
BR (1) BRPI9914698B8 (el)
CA (1) CA2346996C (el)
CY (4) CY1107526T1 (el)
CZ (1) CZ302155B6 (el)
DE (2) DE122009000039I1 (el)
DK (3) DK2319928T3 (el)
EA (1) EA003998B1 (el)
ES (3) ES2279649T3 (el)
FR (1) FR09C0030I2 (el)
HK (2) HK1042114B (el)
HU (1) HU228582B1 (el)
IL (1) IL142023A0 (el)
LT (1) LTC1124961I2 (el)
LU (1) LU91598I2 (el)
ME (2) ME00238B (el)
MY (1) MY126795A (el)
NL (1) NL300398I2 (el)
NO (2) NO331027B1 (el)
NZ (1) NZ510529A (el)
PL (1) PL219605B1 (el)
PT (3) PT1124961E (el)
RS (1) RS51237B (el)
SI (3) SI1124961T1 (el)
SK (1) SK287737B6 (el)
TW (2) TWI257394B (el)
WO (1) WO2000024770A2 (el)
ZA (1) ZA200102102B (el)

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ATE348163T1 (de) 2007-01-15
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US20060189531A1 (en) 2006-08-24
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