MA49562A - Système d'insertion-rétractation d'aiguille présentant un système à ressort en double torsion - Google Patents

Système d'insertion-rétractation d'aiguille présentant un système à ressort en double torsion

Info

Publication number
MA49562A
MA49562A MA049562A MA49562A MA49562A MA 49562 A MA49562 A MA 49562A MA 049562 A MA049562 A MA 049562A MA 49562 A MA49562 A MA 49562A MA 49562 A MA49562 A MA 49562A
Authority
MA
Morocco
Prior art keywords
double
torsion spring
needle insertion
featuring
retraction
Prior art date
Application number
MA049562A
Other languages
English (en)
Inventor
Scott Robert Gibson
Adam Livingston
Mehran Mojarrad
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Inc filed Critical Amgen Inc
Publication of MA49562A publication Critical patent/MA49562A/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
    • A61M5/14248—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body of the skin patch type
    • A61M2005/14252—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body of the skin patch type with needle insertion means
    • A61M2005/14256—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body of the skin patch type with needle insertion means with means for preventing access to the needle after use
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
    • A61M2005/14506—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons mechanically driven, e.g. spring or clockwork
MA049562A 2017-07-14 2018-07-03 Système d'insertion-rétractation d'aiguille présentant un système à ressort en double torsion MA49562A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201762532868P 2017-07-14 2017-07-14

Publications (1)

Publication Number Publication Date
MA49562A true MA49562A (fr) 2020-05-20

Family

ID=63013119

Family Applications (1)

Application Number Title Priority Date Filing Date
MA049562A MA49562A (fr) 2017-07-14 2018-07-03 Système d'insertion-rétractation d'aiguille présentant un système à ressort en double torsion

Country Status (6)

Country Link
US (1) US11305056B2 (fr)
EP (1) EP3651832B1 (fr)
JP (1) JP7408398B2 (fr)
IL (1) IL270784B2 (fr)
MA (1) MA49562A (fr)
WO (1) WO2019014014A1 (fr)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE602005023458D1 (de) 2005-09-12 2010-10-21 Unomedical As Einfürungssystem für ein Infusionsset mit einem ersten und zweiten Federeinheit
US10194938B2 (en) 2011-03-14 2019-02-05 UnoMedical, AS Inserter system with transport protection
EP3852840A1 (fr) * 2018-09-22 2021-07-28 SHL Medical AG Ensemble d'insertion rétraction d'aiguille d'injecteur
FR3093437A1 (fr) * 2019-03-07 2020-09-11 Nemera La Verpilliere Dispositif d’insertion d’une aiguille pour la distribution d’un produit dans un site
WO2020236796A1 (fr) 2019-05-20 2020-11-26 Unomedical A/S Dispositif de perfusion rotative et méthodes associées
US11806505B2 (en) * 2020-12-02 2023-11-07 Medtronic Minimed, Inc. Single-site insertion of multiple medical devices
US11311666B1 (en) 2021-02-18 2022-04-26 Fresenius Kabi Deutschland Gmbh Modular wearable medicament delivery device and method of use thereof
US11872369B1 (en) 2021-02-18 2024-01-16 Fresenius Kabi Deutschland Gmbh Wearable medicament delivery device with leakage and skin contact sensing and method of use thereof
US11464902B1 (en) 2021-02-18 2022-10-11 Fresenius Kabi Deutschland Gmbh Wearable medicament delivery device with compressible reservoir and method of use thereof
US11406755B1 (en) 2021-02-19 2022-08-09 Fresenius Kabi Deutschland Gmbh Sensing fluid flow irregularities in an on-body injector
US11497847B1 (en) 2021-02-19 2022-11-15 Fresenius Kabi Deutschland Gmbh Wearable injector with adhesive substrate
US11633537B1 (en) 2021-02-19 2023-04-25 Fresenius Kabi Deutschland Gmbh Drug delivery assembly including a pre-filled cartridge
US11344682B1 (en) 2021-02-19 2022-05-31 Fresenius Kabi Deutschland Gmbh Drug supply cartridge with visual use indicator and delivery devices that use the same
US11607505B1 (en) 2021-02-19 2023-03-21 Fresenius Kabi Deutschland Gmbh Wearable injector with sterility sensors
US11426523B1 (en) 2021-02-19 2022-08-30 Fresenius Kabi Deutschland Gmbh Drug delivery assembly including a removable cartridge
US11413394B1 (en) 2021-02-19 2022-08-16 Fresenius Kabi Deutschland Gmbh Display for wearable drug delivery device
US11504470B1 (en) 2021-04-30 2022-11-22 Fresenius Kabi Deutschland Gmbh Deformable drug reservoir for wearable drug delivery device
US11529459B1 (en) 2021-04-30 2022-12-20 Fresenius Kabi Deutschland Gmbh Wearable injector with adhesive module
US11351300B1 (en) 2021-04-30 2022-06-07 Fresenius Kabl Deutschland GmbH Drug dispensing system with replaceable drug supply cartridges
US11419976B1 (en) 2021-04-30 2022-08-23 Fresenius Kabi Deutschland Gmbh Wearable drug delivery device with pressurized fluid dispensing
US11717608B1 (en) 2021-05-03 2023-08-08 Fresenius Kabi Deutschland Gmbh Drug delivery assembly including an adhesive pad
US11484646B1 (en) 2021-05-04 2022-11-01 Fresenius Kabi Deutschland Gmbh Sealing systems for a reservoir of an on-body injector

Family Cites Families (212)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1471091A (en) 1922-03-27 1923-10-16 Alfred N Bessesen Fluid-pressure device
GB1017496A (fr) 1961-11-24
US3115133A (en) 1962-05-15 1963-12-24 Morando Emilio Donald Needleless prefilled disposable hypodermic injector
FR2237643B1 (fr) 1973-07-17 1978-03-17 Steiner Maurice
KR850004274A (ko) 1983-12-13 1985-07-11 원본미기재 에리트로포이에틴의 제조방법
NZ210501A (en) 1983-12-13 1991-08-27 Kirin Amgen Inc Erythropoietin produced by procaryotic or eucaryotic expression of an exogenous dna sequence
US4703008A (en) 1983-12-13 1987-10-27 Kiren-Amgen, Inc. DNA sequences encoding erythropoietin
US4861335A (en) 1985-07-26 1989-08-29 Duoject Medical Systems Inc. Syringe
EP0243249A1 (fr) 1986-04-18 1987-10-28 Maurice Carre Dispositif de distribution, notamment à usage médical, d'un produit suivant des quantités dosées prédéterminées
US4790824A (en) 1987-06-19 1988-12-13 Bioject, Inc. Non-invasive hypodermic injection device
US4926860A (en) 1988-02-05 1990-05-22 Flexmedics Corporation ARthroscopic instrumentation and method
US5856298A (en) 1989-10-13 1999-01-05 Amgen Inc. Erythropoietin isoforms
AU646822B2 (en) 1989-10-13 1994-03-10 Kirin-Amgen Inc. Erythropoietin isoforms
US7217689B1 (en) 1989-10-13 2007-05-15 Amgen Inc. Glycosylation analogs of erythropoietin
GB9111600D0 (en) 1991-05-30 1991-07-24 Owen Mumford Ltd Improvements relating to injection devices
IL192290A0 (en) 1993-08-17 2008-12-29 Kirin Amgen Inc Erythropoietin analogs
US6562596B1 (en) 1993-10-06 2003-05-13 Amgen Inc. Tissue inhibitor of metalloproteinase type three (TIMP-3) composition and methods
US5830851A (en) 1993-11-19 1998-11-03 Affymax Technologies N.V. Methods of administering peptides that bind to the erythropoietin receptor
US5773569A (en) 1993-11-19 1998-06-30 Affymax Technologies N.V. Compounds and peptides that bind to the erythropoietin receptor
US5437640A (en) 1994-01-31 1995-08-01 Schwab; Louis Apparatus and method for inserting hypodermic, tuberculin and other needles and for administering Mantoux tuberculin tests
US5885574A (en) 1994-07-26 1999-03-23 Amgen Inc. Antibodies which activate an erythropoietin receptor
DE69534530T2 (de) 1994-08-12 2006-07-06 Immunomedics, Inc. Für b-zell-lymphom und leukämiezellen spezifische immunkonjugate und humane antikörper
DE29507987U1 (de) 1995-05-15 1996-09-19 Ferton Holding Ejektionsgerät zur Hochdruckejektion einer Flüssigkeit
US5686292A (en) 1995-06-02 1997-11-11 Genentech, Inc. Hepatocyte growth factor receptor antagonist antibodies and uses thereof
US5767078A (en) 1995-06-07 1998-06-16 Johnson; Dana L. Agonist peptide dimers
KR100469207B1 (ko) 1995-10-20 2005-03-16 화이자 헬스 에이비 전자식주입조정장치
US6753165B1 (en) 1999-01-14 2004-06-22 Bolder Biotechnology, Inc. Methods for making proteins containing free cysteine residues
JP2001510033A (ja) 1997-07-14 2001-07-31 ボルダー バイオテクノロジー， インコーポレイテッド 成長ホルモンおよび関連タンパク質の誘導体
KR100641969B1 (ko) 1997-07-23 2006-11-06 로셰 디아그노스틱스 게엠베하 내인성 유전자 활성화에 의한 에리트로포이에틴의제조방법
US6030086A (en) 1998-03-02 2000-02-29 Becton, Dickinson And Company Flash tube reflector with arc guide
US6310078B1 (en) 1998-04-20 2001-10-30 Ortho-Mcneil Pharmaceutical, Inc. Substituted amino acids as erythropoietin mimetics
CA2330527A1 (fr) 1998-06-15 1999-12-23 Genzyme Transgenics Corporation Fusion analogue d'erythropoietine-albumine serique humaine
US20050181482A1 (en) 2004-02-12 2005-08-18 Meade Harry M. Method for the production of an erythropoietin analog-human IgG fusion proteins in transgenic mammal milk
EP1813624B1 (fr) 1998-10-23 2010-08-11 Amgen Inc. Procédés et compositions pour la prévention et le traitement de l'anémie
ME00238B (me) 1998-10-23 2011-02-10 Kirin Amgen Inc Mimičko vezivanje dimernog trombopoitetinskog peptida za mp1 receptor sa trombopoietičkom aktivnošću
US6605067B1 (en) 1998-11-20 2003-08-12 Novo Nordisk A/S Injection needle
CN1333828B (zh) 1998-11-27 2015-05-13 Ucb医药有限公司 增加骨矿化的组合物和方法
EP1006184A1 (fr) 1998-12-03 2000-06-07 F. Hoffmann-La Roche Ag Protéines interagissant avec le récepteur de IGF-1, gènes codant pour ces protéines et leurs utilisations
GB9903475D0 (en) 1999-02-17 1999-04-07 Owen Mumford Ltd Improvements relating to injection devices
JP2002544123A (ja) 1999-04-14 2002-12-24 スミスクライン・ビーチャム・コーポレイション エリトロポイエチン受容体抗体
US7297680B2 (en) 1999-04-15 2007-11-20 Crucell Holland B.V. Compositions of erythropoietin isoforms comprising Lewis-X structures and high sialic acid content
CZ299516B6 (cs) 1999-07-02 2008-08-20 F. Hoffmann-La Roche Ag Konjugát erythropoetinového glykoproteinu, zpusobjeho výroby a použití a farmaceutická kompozice sjeho obsahem
WO2001031007A2 (fr) 1999-10-22 2001-05-03 Millennium Pharmaceuticals, Inc. Molecules d'acide nucleique derivees d'un cerveau de rat et modeles de mort cellulaire programmee
WO2001036489A2 (fr) 1999-11-12 2001-05-25 Merck Patent Gmbh Formes d'erythropoietine dotees de proprietes ameliorees
US20050202538A1 (en) 1999-11-12 2005-09-15 Merck Patent Gmbh Fc-erythropoietin fusion protein with improved pharmacokinetics
ATE282708T1 (de) 2000-01-21 2004-12-15 Biovex Ltd Herpes-virusstämme für die gentherapie
AUPQ599700A0 (en) 2000-03-03 2000-03-23 Super Internet Site System Pty Ltd On-line geographical directory
US6586398B1 (en) 2000-04-07 2003-07-01 Amgen, Inc. Chemically modified novel erythropoietin stimulating protein compositions and methods
ATE395357T1 (de) 2000-04-21 2008-05-15 Amgen Inc Verfahren und zusammensetzungen zur vermeidung und behandlung von anämie
US6756480B2 (en) 2000-04-27 2004-06-29 Amgen Inc. Modulators of receptors for parathyroid hormone and parathyroid hormone-related protein
US7530964B2 (en) 2000-06-30 2009-05-12 Elan Pharma International Limited Needle device and method thereof
US7078376B1 (en) 2000-08-11 2006-07-18 Baxter Healthcare S.A. Therapeutic methods for treating subjects with a recombinant erythropoietin having high activity and reduced side effects
WO2002017996A1 (fr) 2000-08-29 2002-03-07 Novo Nordisk A/S Dispositif automatique d'injection a retrait de l'aiguille par torsion
CZ2003678A3 (cs) 2000-09-08 2004-03-17 Gryphon Therapeutics, Inc. Syntetické proteiny stimulující erytropoézu
CN100366305C (zh) 2000-11-09 2008-02-06 茵斯莱特有限公司 经皮给药装置
US7271689B1 (en) 2000-11-22 2007-09-18 Fonar Corporation Magnet structure
WO2002049673A2 (fr) 2000-12-20 2002-06-27 F. Hoffmann-La Roche Ag Conjugues d'erythropoietine
US6387078B1 (en) 2000-12-21 2002-05-14 Gillespie, Iii Richard D. Automatic mixing and injecting apparatus
CA2433800C (fr) 2001-01-05 2016-09-13 Pfizer Inc. Anticorps anti-recepteur du facteur de croissance insulinoide i
IL158261A0 (en) 2001-04-04 2004-05-12 Genodyssee New polynucleotides and polypeptides of the erythropoietin gene
NZ529267A (en) 2001-05-11 2006-05-26 Amgen Inc Peptides and related molecules that bind to tall-1
TR201809008T4 (tr) 2001-06-26 2018-07-23 Amgen Fremont Inc Opgl ye karşi antikorlar.
US6900292B2 (en) 2001-08-17 2005-05-31 Lee-Hwei K. Sun Fc fusion proteins of human erythropoietin with increased biological activities
US7247304B2 (en) 2001-08-23 2007-07-24 Genmab A/S Methods of treating using anti-IL-15 antibodies
EA014802B1 (ru) 2001-08-23 2011-02-28 Генмаб А/С АНТИТЕЛА К ИНТЕРЛЕЙКИНУ 15 (ВАРИАНТЫ), СПОСОБ ИХ ПОЛУЧЕНИЯ, ИММУНОКОНЪЮГАТ НА ИХ ОСНОВЕ, ГИБРИДОМА, ТРАНСФЕКТОМА, ТРАНСГЕННОЕ ЖИВОТНОЕ, ЭКСПРЕССИОННЫЙ ВЕКТОР (ВАРИАНТЫ) И НУКЛЕИНОВАЯ КИСЛОТА ДЛЯ ИХ ПОЛУЧЕНИЯ, СПОСОБ ЛЕЧЕНИЯ (ВАРИАНТЫ) И СПОСОБ ДИАГНОСТИКИ ЗАБОЛЕВАНИЙ, ОПОСРЕДОВАННЫХ ИЛ-15, СПОСОБ ИНГИБИРОВАНИЯ ИНДУЦИРОВАННОЙ ИЛ-15 ПРОДУКЦИИ TNF-α И СПОСОБ ИНГИБИРОВАНИЯ ИНДУЦИРОВАННОЙ ИЛ-15 ПРОЛИФЕРАЦИИ КЛЕТОК
US6930086B2 (en) 2001-09-25 2005-08-16 Hoffmann-La Roche Inc. Diglycosylated erythropoietin
US7214660B2 (en) 2001-10-10 2007-05-08 Neose Technologies, Inc. Erythropoietin: remodeling and glycoconjugation of erythropoietin
US7138370B2 (en) 2001-10-11 2006-11-21 Amgen Inc. Specific binding agents of human angiopoietin-2
US7521053B2 (en) 2001-10-11 2009-04-21 Amgen Inc. Angiopoietin-2 specific binding agents
WO2003039634A1 (fr) 2001-11-09 2003-05-15 Alza Corporation Auto-injecteur pneumatique
AU2002351746A1 (en) 2001-12-21 2003-07-15 Maxygen Aps Erythropoietin conjugates
EP1798242B1 (fr) 2002-01-18 2013-01-23 Pierre Fabre Medicament Anticorps anti-IGF-IR et leurs applications
US7241444B2 (en) 2002-01-18 2007-07-10 Pierre Fabre Medicament Anti-IGF-IR antibodies and uses thereof
WO2003064664A1 (fr) 2002-01-31 2003-08-07 Oxford Biomedica (Uk) Limited Vecteur d'expression de l'erythropoietine physiologiquement regule, destine au traitement de l'anemie
GB0202252D0 (en) 2002-01-31 2002-03-20 Oxford Biomedica Ltd Anemia
JP4109204B2 (ja) 2002-03-26 2008-07-02 レツク・フアーマシユーテイカルズ・デー・デー 所望エリスロポエチングリコアイソフォームプロフィールの製造方法
EP1572079A4 (fr) 2002-03-29 2006-09-06 Centocor Inc Corps mimetiques de cdr de mammifere, compositions, procedes et utilisations
ATE434662T1 (de) 2002-03-29 2009-07-15 Kumiai Chemical Industry Co Acetolactatsynthase codierende gene
CA2485365A1 (fr) 2002-05-13 2003-11-20 Modigenetech Ltd. Erythropoietine comportant une extension ctp
PL210412B1 (pl) 2002-05-24 2012-01-31 Schering Corp Izolowane przeciwciało anty-IGFR lub jego fragment, kompozycja farmaceutyczna, zastosowanie, kwas nukleinowy, zrekombinowany wektor, komórka gospodarza, kompleks, polipeptyd i sposób jego wytwarzania
US8034904B2 (en) 2002-06-14 2011-10-11 Immunogen Inc. Anti-IGF-I receptor antibody
US7538195B2 (en) 2002-06-14 2009-05-26 Immunogen Inc. Anti-IGF-I receptor antibody
AU2003280130B2 (en) 2002-06-28 2009-06-11 Centocor, Inc. Mammalian CH1 deleted mimetibodies, compositions, methods and uses
BR0312276A (pt) 2002-06-28 2005-04-26 Centocor Inc Mimeticorpos ch1-removidos miméticos de epo de mamìfero, composições, métodos e usos
AU2003246486A1 (en) 2002-07-19 2004-02-09 Cangene Corporation Pegylated erythropoietic compounds
AU2003254950A1 (en) 2002-08-26 2004-03-11 Kirin Beer Kabushiki Kaisha Peptides and drugs containing the same
EP1572946B1 (fr) 2002-09-06 2012-03-14 Amgen, Inc. Anticorps monoclonal therapeutique anti-il-1r1 humain
BR0314227A (pt) 2002-09-11 2005-10-25 Fresenius Kabi De Gmbh Derivados de amido de hidroxialquila
US6919426B2 (en) 2002-09-19 2005-07-19 Amgen Inc. Peptides and related molecules that modulate nerve growth factor activity
TWI320716B (en) 2002-10-14 2010-02-21 Abbott Lab Erythropoietin receptor binding antibodies
US20040071694A1 (en) 2002-10-14 2004-04-15 Devries Peter J. Erythropoietin receptor binding antibodies
US7396913B2 (en) 2002-10-14 2008-07-08 Abbott Laboratories Erythropoietin receptor binding antibodies
US7335743B2 (en) 2002-10-16 2008-02-26 Amgen Inc. Human anti-IFN-γ neutralizing antibodies as selective IFN-γ pathway inhibitors
US20040091961A1 (en) 2002-11-08 2004-05-13 Evans Glen A. Enhanced variants of erythropoietin and methods of use
KR20120060250A (ko) 2002-12-20 2012-06-11 암겐 인코포레이티드 미오스타틴을 저해하는 결합제
MXPA05009837A (es) 2003-03-14 2005-12-05 Pharmacia Corp Anticuerpos para el receptor del factor de crecimiento tipo insulina-i, para el tratamiento de canceres.
CA2519113C (fr) 2003-04-02 2012-06-05 F. Hoffmann-La Roche Ag Anticorps contre le recepteur du facteur de croissance 1 analogue a l'insuline et utilisations de ceux-ci
US7220410B2 (en) 2003-04-18 2007-05-22 Galaxy Biotech, Llc Monoclonal antibodies to hepatocyte growth factor
EP2365001A3 (fr) 2003-05-01 2012-03-28 Imclone LLC Anticorps humains dirigés contre le récepteur de facteur 1 de croissance de type insuline humaine
TWI353991B (en) 2003-05-06 2011-12-11 Syntonix Pharmaceuticals Inc Immunoglobulin chimeric monomer-dimer hybrids
ES2323465T3 (es) 2003-05-12 2009-07-16 Affymax, Inc. Peptidos novedosos que se unen al receptor de la eritropoyetina.
EA010099B1 (ru) 2003-05-12 2008-06-30 Афимакс, Инк. Пептиды, которые связываются с рецептором к эритропоэтину, и способы их применения
CA2525464A1 (fr) 2003-05-12 2004-11-25 Qun Yin Nouveaux composes modifies par du poly(ethylene glycol) et leurs utilisations
US7074755B2 (en) 2003-05-17 2006-07-11 Centocor, Inc. Erythropoietin conjugate compounds with extended half-lives
MXPA05012936A (es) 2003-05-30 2006-05-17 Johnson & Johnson Formacion de conjugados novedosos de eritropoietina utilizando transglutaminasa.
WO2005001136A1 (fr) 2003-06-04 2005-01-06 Irm Llc Methodes et compositions pour la modulation de l'expression de l'erythropoietine
US7579157B2 (en) 2003-07-10 2009-08-25 Hoffmann-La Roche Inc. Antibody selection method against IGF-IR
JP4489077B2 (ja) 2003-07-15 2010-06-23 アムジェン インコーポレイテッド 選択的ｎｇｆ経路インヒビターとしてのヒト抗ｎｇｆ中和抗体
MEP31408A (en) 2003-07-18 2010-10-10 Abgenix Inc Specific binding agents to hepatocyte growth factor
US20050019914A1 (en) 2003-07-24 2005-01-27 Aventis Pharma Deutschland Gmbh Perfusion process for producing erythropoietin
GB0317511D0 (en) 2003-07-25 2003-08-27 Biovex Ltd Viral vectors
US20050159676A1 (en) 2003-08-13 2005-07-21 Taylor James D. Targeted biopsy delivery system
WO2005021579A2 (fr) 2003-08-28 2005-03-10 Biorexis Pharmaceutical Corporation Peptides mimetiques epo et proteines de fusion
CN1882355A (zh) 2003-09-09 2006-12-20 沃伦药品公司 保持内源性促红细胞生成素组织保护活性的长效促红细胞生成素
AU2004316266A1 (en) 2003-09-30 2005-09-09 Centocor, Inc. Human hinge core mimetibodies, compositions, methods and uses
UA89481C2 (uk) 2003-09-30 2010-02-10 Центокор, Инк. Еритропоетинові міметичні шарнірно-серцевинні міметитіла людини, композиції, способи та застосування
KR101225463B1 (ko) 2003-11-07 2013-01-24 임뮤넥스 코포레이션 인터류킨-4 수용체에 결합하는 항체
PE20050928A1 (es) 2003-11-21 2005-11-08 Schering Corp Combinaciones terapeuticas de anticuerpo anti-igfr1
NZ547168A (en) 2003-11-24 2010-05-28 Biogenerix Ag Glycopegylated erythropoietin
US8633157B2 (en) 2003-11-24 2014-01-21 Novo Nordisk A/S Glycopegylated erythropoietin
WO2005058967A2 (fr) 2003-12-16 2005-06-30 Pierre Fabre Medicament Nouveau recepteur hybride anti-insuline/igf-i ou recepteur hybride anti-insuline/igf-i et anticorps igf-ir et applications
EP1548031A1 (fr) 2003-12-22 2005-06-29 Dubai Genetics FZ-LLC Erythropoietin identique à la nature
PT1699821E (pt) 2003-12-31 2012-08-23 Merck Patent Gmbh Proteína de fusão fc-eritropoietina com farmacocinética melhorada
EP1699920A4 (fr) 2003-12-31 2008-05-28 Centocor Inc Nouvelles proteines recombinees avec thiol libre n-terminal
US7423139B2 (en) 2004-01-20 2008-09-09 Insight Biopharmaceuticals Ltd. High level expression of recombinant human erythropoietin having a modified 5′-UTR
WO2005070451A1 (fr) 2004-01-22 2005-08-04 Zafena Aktiebolag Composition pharmaceutique comprenant une erythropoietine non glycosylee
WO2005084711A1 (fr) 2004-03-02 2005-09-15 Chengdu Institute Of Biological Products Erythropoietine recombinante pegylee a activite in vivo
EP1758608A2 (fr) 2004-03-11 2007-03-07 Fresenius Kabi Deutschland GmbH Conjugues d'hydroxy-ethyl-amidon et d'erythropoietine
US20060002929A1 (en) 2004-03-23 2006-01-05 Khare Sanjay D Monoclonal antibodies
US20050227289A1 (en) 2004-04-09 2005-10-13 Reilly Edward B Antibodies to erythropoietin receptor and uses thereof
US20080194475A1 (en) 2004-04-23 2008-08-14 Andrew Buchanan Erythropoietin Protein Variants
PL1781697T3 (pl) 2004-07-07 2009-10-30 H Lundbeck As Nowa karbamylowana EPO i sposób jej wytwarzania
FR2873699B1 (fr) 2004-07-29 2009-08-21 Pierre Fabre Medicament Sa Nouveaux anticorps anti igf ir rt leurs utilisations
WO2006029094A2 (fr) 2004-09-02 2006-03-16 Xencor, Inc. Derives d'erythropoietine a antigenicite modifiee
JP5185620B2 (ja) 2004-10-21 2013-04-17 ノボ・ノルデイスク・エー／エス ねじりバネ及び回転表示器を備えた注入装置
WO2006050959A2 (fr) 2004-11-10 2006-05-18 Aplagen Gmbh Molecules favorisant l'hematopoiese
MY146381A (en) 2004-12-22 2012-08-15 Amgen Inc Compositions and methods relating relating to anti-igf-1 receptor antibodies
AU2006208226A1 (en) 2005-01-24 2006-08-03 Amgen Inc. Humanized anti-amyloid antibody
US7592429B2 (en) 2005-05-03 2009-09-22 Ucb Sa Sclerostin-binding antibody
DE102005025424A1 (de) 2005-06-02 2006-12-07 Tecpharma Licensing Ag Injektionsvorrichtung mit einem Drehfederantrieb
DK2100618T3 (en) 2005-06-17 2014-03-03 Imclone Llc Anti-PDGFR alpha antibody for use in the treatment of metastatic bone cancer
WO2007000328A1 (fr) 2005-06-27 2007-01-04 Istituto Di Ricerche Di Biologia Molecolare P Angeletti Spa Anticorps se fixant à un épitope sur un récepteur de facteur de croissance insulinomimétique de type 1 et leurs utilisations
CN101208130B (zh) 2005-06-27 2012-05-16 3M创新有限公司 微针阵列施放器装置
UA102667C2 (uk) 2005-07-18 2013-08-12 Емджен Інк. Людське нейтралізуюче антитіло проти в7rp1
FR2888850B1 (fr) 2005-07-22 2013-01-11 Pf Medicament Nouveaux anticorps anti-igf-ir et leurs applications
PE20071101A1 (es) 2005-08-31 2007-12-21 Amgen Inc Polipeptidos y anticuerpos
GB0603683D0 (en) 2006-02-23 2006-04-05 Novartis Ag Organic compounds
TWI395754B (zh) 2006-04-24 2013-05-11 Amgen Inc 人類化之ｃ-ｋｉｔ抗體
EP2032600A2 (fr) 2006-05-19 2009-03-11 Glycofi, Inc. Compositions d'érythropoïétine
CL2007002567A1 (es) 2006-09-08 2008-02-01 Amgen Inc Proteinas aisladas de enlace a activina a humana.
US20100040610A1 (en) 2006-11-07 2010-02-18 Ayesha Sitlani Antagonists of pcsk9
EP2083859A4 (fr) 2006-11-07 2010-11-24 Merck Sharp & Dohme Antagonistes de pcsk9
CA2667869A1 (fr) 2006-11-07 2008-05-15 Merck & Co., Inc. Antagonistes de pcsk9
EP2083861A4 (fr) 2006-11-07 2010-11-24 Merck Sharp & Dohme Antagonistes de pcsk9
AR064333A1 (es) 2006-12-14 2009-04-01 Schering Corp Anticuerpo anti-tslp de diseno
EP2137218A2 (fr) 2007-04-13 2009-12-30 Novartis Ag Molécules et procédés de modulation de proprotéine convertase subtilisine/kexine de type 9 (pcsk9)
AU2008265128A1 (en) 2007-06-20 2008-12-24 Irm Llc Methods and compositions for treating allergic diseases
CN101687079B (zh) 2007-07-06 2013-01-02 诺沃-诺迪斯克有限公司 自动注射装置
US7982016B2 (en) 2007-09-10 2011-07-19 Amgen Inc. Antigen binding proteins capable of binding thymic stromal lymphopoietin
DE102007049446A1 (de) 2007-10-16 2009-04-23 Cequr Aps Katheter-Einführeinrichtung
BRPI0818765A8 (pt) 2007-10-26 2016-02-10 Schering Corp Polipeptídeo, anticorpo ou seu fragmento de ligação de antígeno, polinucleotídeo, célula hospedeira, vetor, composição, uso e método para produzir polipeptídeo
WO2009086250A1 (fr) 2007-12-21 2009-07-09 Aesthetic Sciences Corporation Dispositif d'injection pressurisé autocontenu
AR070315A1 (es) 2008-02-07 2010-03-31 Merck & Co Inc Anticuerpos 1b20 antagonistas de pcsk9
AR070316A1 (es) 2008-02-07 2010-03-31 Merck & Co Inc Antagonistas de pcsk9 (proproteina subtilisina-kexina tipo 9)
TWI445716B (zh) 2008-09-12 2014-07-21 Rinat Neuroscience Corp Ｐｃｓｋ９拮抗劑類
JO3672B1 (ar) 2008-12-15 2020-08-27 Regeneron Pharma أجسام مضادة بشرية عالية التفاعل الكيماوي بالنسبة لإنزيم سبتيليسين كنفرتيز بروبروتين / كيكسين نوع 9 (pcsk9).
JO3382B1 (ar) 2008-12-23 2019-03-13 Amgen Inc أجسام مضادة ترتبط مع مستقبل cgrp بشري
DE102009025375A1 (de) 2009-06-18 2010-12-23 Arzneimittel Gmbh Apotheker Vetter & Co. Ravensburg Kolben für einen medizinischen Hohlkörper und medizinischer Hohlkörper
US8932256B2 (en) * 2009-09-02 2015-01-13 Medtronic Minimed, Inc. Insertion device systems and methods
EP2480576A4 (fr) 2009-09-25 2013-04-10 Merck Sharp & Dohme Antagonistes de pcsk9
IN2012DN03824A (fr) 2009-10-30 2015-08-28 Merck Sharp & Dohme
CA2777698A1 (fr) 2009-10-30 2011-05-05 Merck Sharp & Dohme Corp. Antagonistes de la pcsk9 avec anticorps fab ax189 et ax1, et variantes afferentes
AR079336A1 (es) 2009-12-11 2012-01-18 Irm Llc Antagonistas de la pro-proteina convertasa-subtilisina/quexina tipo 9 (pcsk9)
CA2789590A1 (fr) 2010-02-18 2011-08-25 Sanofi-Aventis Deutschland Gmbh Injecteur automatique avec un ressort de torsion
WO2011101378A1 (fr) 2010-02-18 2011-08-25 Sanofi-Aventis Deutschland Gmbh Gaine d'aiguille pour un dispositif d'injection
CA2789596A1 (fr) 2010-02-18 2011-08-25 Sanofi-Aventis Deutschland Gmbh Mecanisme d'embrayage
JP5797209B2 (ja) 2010-02-18 2015-10-21 サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング 自動注射器
PT2542280E (pt) 2010-03-01 2014-09-12 Lilly Co Eli Dispositivo automático de injecção com mecanismo de atraso que inclui um membro de pressionar de dupla função
MX2012010481A (es) 2010-03-11 2012-10-09 Rinat Neuroscience Corp Anticuerpos con union de antigenos dependiente del ph.
AU2011265005B2 (en) 2010-06-07 2015-04-09 Amgen Inc. Drug delivery device
GB201015799D0 (en) 2010-09-21 2010-10-27 Owen Mumford Ltd Autoinjectors
EP2438940A1 (fr) 2010-10-08 2012-04-11 Sanofi-Aventis Deutschland GmbH Auto-injecteur avec un ressort à torsion
EP2438941A1 (fr) 2010-10-08 2012-04-11 Sanofi-Aventis Deutschland GmbH Auto-injecteur avec un ressort à torsion
WO2012054438A1 (fr) 2010-10-22 2012-04-26 Schering Corporation Anti-pcsk9
WO2012134589A1 (fr) 2011-02-09 2012-10-04 Becton, Dickinson And Company Dispositif d'insertion de ressort de torsion autocontenu pour un ensemble de perfusion pour l'administration de médicament
EP2468337A1 (fr) 2010-12-21 2012-06-27 Sanofi-Aventis Deutschland GmbH Dispositif secondaire pour auto-injecteur et auto-injecteur
EP2468336A1 (fr) 2010-12-21 2012-06-27 Sanofi-Aventis Deutschland GmbH Auto-injecteur
EP2468328A1 (fr) 2010-12-21 2012-06-27 Sanofi-Aventis Deutschland GmbH Auto-injecteur
EP2468329A1 (fr) 2010-12-21 2012-06-27 Sanofi-Aventis Deutschland GmbH Auto-injecteur avec ressort à torsion
KR20130118925A (ko) 2010-12-22 2013-10-30 제넨테크, 인크. 항-pcsk9 항체 및 사용 방법
GB2487235A (en) 2011-01-17 2012-07-18 Owen Mumford Ltd Injection device with pneumatic damping of the drive mechanism
JP5917565B2 (ja) * 2011-01-27 2016-05-18 メドトロニック ミニメド インコーポレイテッド 挿入デバイスシステムおよび方法
AR084938A1 (es) 2011-01-28 2013-07-10 Sanofi Sa Anticuerpos humanos contra la proproteina convertasa subtilisina/kexina tipo 9 (anti pcsk9) para usar en metodos para tratar grupos de pacientes
EP2673302A1 (fr) 2011-02-11 2013-12-18 Irm Llc Antagonistes de pcsk9
JOP20200043A1 (ar) 2011-05-10 2017-06-16 Amgen Inc طرق معالجة أو منع الاضطرابات المختصة بالكوليسترول
US8808244B2 (en) 2011-08-24 2014-08-19 Unitract Syringe Pty Ltd Auto-injector for retractable prefilled syringe
EP2785395A4 (fr) 2011-12-02 2015-11-11 Trendymed Inc Dispositif de perfusion mobile
JP6069351B2 (ja) 2011-12-29 2017-02-01 ノボ・ノルデイスク・エー／エス ダイアルアップ／ダイアルダウン投与機構を有するねじりバネ式ねじ巻き自動注射器
CN104394911B (zh) 2012-05-25 2017-03-01 阿普塔尔法国简易股份公司 自动注射器
US20140088555A1 (en) 2012-09-24 2014-03-27 Po-Ying Li Systems and Methods for Electrolysis Pump Control
WO2014099984A1 (fr) 2012-12-20 2014-06-26 Amgen Inc. Agonistes du récepteur apj et leurs utilisations
US20140274874A1 (en) 2013-03-14 2014-09-18 Amgen Inc. Variants of tissue inhibitor of metalloproteinase type three (timp-3), compositions and methods
MX2015012891A (es) 2013-03-14 2015-12-03 Amgen Inc Composiciones y metodos de variantes de inhibidor tisular de la metaloproteinasa tipo tres (timp-3).
WO2014198858A1 (fr) 2013-06-14 2014-12-18 Novo Nordisk A/S Dispositif de distribution de médicament comprenant un ressort à deux enroulements
TR201902021T4 (tr) * 2013-09-05 2019-03-21 Sanofi Aventis Deutschland Manüel olarak tetiklemeli, yay yüklü tahrik mekanizması ile iğne insersiyon ve retraksiyon düzeni.
TWI569841B (zh) 2013-10-10 2017-02-11 卡貝歐洲有限公司 藥物輸送裝置
US10195342B2 (en) * 2014-04-24 2019-02-05 Becton, Dickinson And Company Cannula deployment mechanism
TW201603852A (zh) 2014-07-01 2016-02-01 賽諾菲公司 彈簧裝置及具有該彈簧裝置之藥物傳輸裝置
TW201603847A (zh) 2014-07-01 2016-02-01 賽諾菲公司 注射裝置及組裝方法
JP6608914B2 (ja) 2014-09-15 2019-11-20 ノボ・ノルデイスク・エー／エス ねじりばね駆動注射装置
JP6873920B2 (ja) 2015-02-10 2021-05-19 アムジエン・インコーポレーテツド 薬物送達ポンプ用の回転付勢式挿入機構
JP6957525B2 (ja) * 2016-06-02 2021-11-02 ウェスト ファーマ サービシーズ イスラエル リミテッド ３つの位置による針の退避

Also Published As

Publication number Publication date
JP7408398B2 (ja) 2024-01-05
EP3651832A1 (fr) 2020-05-20
IL270784A (en) 2020-01-30
IL270784B2 (en) 2023-11-01
US20200230313A1 (en) 2020-07-23
IL270784B1 (en) 2023-07-01
JP2020527373A (ja) 2020-09-10
US11305056B2 (en) 2022-04-19
WO2019014014A1 (fr) 2019-01-17
EP3651832B1 (fr) 2023-12-13

Similar Documents

Publication Publication Date Title
MA49562A (fr) Système d'insertion-rétractation d'aiguille présentant un système à ressort en double torsion
DK3376857T3 (da) Ikke-humane dyr, der har et humaniseret lymfocyt-aktiveringsgen 3
DE102017219442B8 (de) Spiegelvorrichtung, die eine Blattfeder mit Öffnungen aufweist
JP2017066272A5 (fr)
IT201700059659A1 (it) Dispositivo portatile per l'inserimento di un ago in un materiale non omogeneo, particolarmente per cateterizzazione endovenosa.
DK3402782T3 (da) 8-amino-2-oxo-1,3-diaza-spiro-[4.5]-decanderivater
PL3580420T3 (pl) Zawias meblowy z elementem blokującym do amortyzatora liniowego
DK3752490T3 (da) Herbicide 3-azaspiro[5.5]undecan-8,10-dionforbindelser
MA51708A (fr) Identification d'applications avec l'apprentissage machine
DK3554490T3 (da) Farmaceutisk kombination omfattende en calciumkanalblokker type T
JP2019502357A5 (fr)
FR3048791B1 (fr) Mecanisme pour piece d'horlogerie et piece d'horlogerie comprenant un tel mecanisme
JP2019106409A5 (fr)
MA46271A (fr) Dispositif d'écartement à portance accrue
DK3451820T3 (da) Kassette og konnektor til en pattekop samt pattekop, der omfatter kassetten og konnektoren
DK3727098T3 (da) Et hyldearrangement
JP2018165688A5 (fr)
EP3403135A4 (fr) Charnière flexible avec ressort de tension
FR3038232B1 (fr) Dispositif d’injection sans aiguille equipe d’un ressort de compression
FR3046841B1 (fr) Couplemetre a torsion
MA45556A (fr) Compte-gouttes à volume contrôlé.
FR3048790B1 (fr) Mecanisme pour piece d'horlogerie, mouvement horloger et piece d'horlogerie comprenant un tel mecanisme.
JP2017186729A5 (fr)
FR3040897B1 (fr) Atomiseur de liquide comportant un element piezoelectrique et fer a repasser comportant un tel atomiseur
FR3024040B1 (fr) Protege-aiguille rigide, procede et machine d'assemblage d'un tel protege-aiguille rigide.