ATE348163T1 - Thrombopoietin substitute - Google Patents

Thrombopoietin substitute

Info

Publication number
ATE348163T1
ATE348163T1 AT99970998T AT99970998T ATE348163T1 AT E348163 T1 ATE348163 T1 AT E348163T1 AT 99970998 T AT99970998 T AT 99970998T AT 99970998 T AT99970998 T AT 99970998T AT E348163 T1 ATE348163 T1 AT E348163T1
Authority
AT
Austria
Prior art keywords
thrombopoietin
substitute
thrombopoietin substitute
Prior art date
Application number
AT99970998T
Other languages
English (en)
Inventor
Chuan-Fa Liu
Ulrich Feige
Janet Cheetham
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Inc filed Critical Amgen Inc
Application granted granted Critical
Publication of ATE348163T1 publication Critical patent/ATE348163T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/524—Thrombopoietin, i.e. C-MPL ligand
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
    • C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT99970998T 1998-10-23 1999-10-22 Thrombopoietin substitute ATE348163T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10534898P 1998-10-23 1998-10-23

Publications (1)

Publication Number Publication Date
ATE348163T1 true ATE348163T1 (de) 2007-01-15

Family

ID=22305310

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99970998T ATE348163T1 (de) 1998-10-23 1999-10-22 Thrombopoietin substitute

Country Status (36)

Country Link
US (8) US6835809B1 (de)
EP (3) EP2319928B9 (de)
JP (2) JP3820105B2 (de)
KR (1) KR100719202B1 (de)
CN (2) CN1810832B (de)
AR (1) AR020934A1 (de)
AT (1) ATE348163T1 (de)
AU (1) AU773891C (de)
BG (3) BG110221A (de)
BR (1) BRPI9914698B8 (de)
CA (1) CA2346996C (de)
CY (4) CY1107526T1 (de)
CZ (1) CZ302155B6 (de)
DE (2) DE69934425T2 (de)
DK (3) DK1783222T3 (de)
EA (1) EA003998B1 (de)
ES (3) ES2279649T3 (de)
FR (1) FR09C0030I2 (de)
HK (2) HK1042114B (de)
HU (1) HU228582B1 (de)
IL (1) IL142023A0 (de)
LT (1) LTC1124961I2 (de)
LU (1) LU91598I2 (de)
ME (2) MEP42108A (de)
MY (1) MY126795A (de)
NL (1) NL300398I2 (de)
NO (2) NO331027B1 (de)
NZ (1) NZ510529A (de)
PL (1) PL219605B1 (de)
PT (3) PT2319928E (de)
RS (1) RS51237B (de)
SI (3) SI1783222T1 (de)
SK (1) SK287737B6 (de)
TW (2) TWI257394B (de)
WO (1) WO2000024770A2 (de)
ZA (1) ZA200102102B (de)

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US20070142295A1 (en) 2007-06-21
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EA003998B1 (ru) 2003-12-25
US20060189531A1 (en) 2006-08-24
ES2388341T3 (es) 2012-10-11
BG105401A (en) 2003-02-28
HU228582B1 (en) 2013-04-29
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CY1114940T1 (el) 2016-12-14
KR100719202B1 (ko) 2007-05-16
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US6835809B1 (en) 2004-12-28
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US20090186822A1 (en) 2009-07-23
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EP1783222B1 (de) 2012-06-06
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