US5521184A
(en)
*
|
1992-04-03 |
1996-05-28 |
Ciba-Geigy Corporation |
Pyrimidine derivatives and processes for the preparation thereof
|
GB9212673D0
(en)
*
|
1992-06-15 |
1992-07-29 |
Celltech Ltd |
Chemical compounds
|
US6171786B1
(en)
|
1992-09-17 |
2001-01-09 |
Board Of Trustees Of University Of Illinois |
Methods for preventing multidrug resistance in cancer cells
|
US5972598A
(en)
*
|
1992-09-17 |
1999-10-26 |
Board Of Trustess Of The University Of Illinois |
Methods for preventing multidrug resistance in cancer cells
|
GB9222253D0
(en)
*
|
1992-10-23 |
1992-12-09 |
Celltech Ltd |
Chemical compounds
|
GB9304919D0
(en)
*
|
1993-03-10 |
1993-04-28 |
Celltech Ltd |
Chemical compounds
|
GB9304920D0
(en)
*
|
1993-03-10 |
1993-04-28 |
Celltech Ltd |
Chemical compounds
|
ES2262137T3
(es)
*
|
1993-10-01 |
2006-11-16 |
Novartis Ag |
Derivados de pirimidinamina farmacologicamente activos y procedimientos para su preparacion.
|
EP0672041B1
(en)
*
|
1993-10-01 |
2001-11-14 |
Novartis AG |
Pharmacologically active pyridine derivatives and processes for the preparation thereof
|
AU693475B2
(en)
*
|
1993-10-01 |
1998-07-02 |
Novartis Ag |
Pyrimidineamine derivatives and processes for the preparation thereof
|
US5543520A
(en)
*
|
1993-10-01 |
1996-08-06 |
Ciba-Geigy Corporation |
Pyrimidine derivatives
|
GB9325217D0
(en)
*
|
1993-12-09 |
1994-02-09 |
Zeneca Ltd |
Pyrimidine derivatives
|
ATE260911T1
(de)
*
|
1993-12-22 |
2004-03-15 |
Celltech R&D Ltd |
Trisubstituierte phenyl-derivate, verfahren zu deren herstellung und deren verwendung als phosphodiesterase (typ iv) hemmstoffe
|
GB9326600D0
(en)
*
|
1993-12-22 |
1994-03-02 |
Celltech Ltd |
Chemical compounds
|
US6245774B1
(en)
|
1994-06-21 |
2001-06-12 |
Celltech Therapeutics Limited |
Tri-substituted phenyl or pyridine derivatives
|
US5786354A
(en)
*
|
1994-06-21 |
1998-07-28 |
Celltech Therapeutics, Limited |
Tri-substituted phenyl derivatives and processes for their preparation
|
GB9412573D0
(en)
*
|
1994-06-22 |
1994-08-10 |
Celltech Ltd |
Chemical compounds
|
GB9412571D0
(en)
*
|
1994-06-22 |
1994-08-10 |
Celltech Ltd |
Chemical compounds
|
GB9412672D0
(en)
*
|
1994-06-23 |
1994-08-10 |
Celltech Ltd |
Chemical compounds
|
US5756527A
(en)
*
|
1995-06-07 |
1998-05-26 |
Ontogen Corporation |
Imidazole derivatives useful as modulators of multi drug resistances
|
GB9523675D0
(en)
*
|
1995-11-20 |
1996-01-24 |
Celltech Therapeutics Ltd |
Chemical compounds
|
GB9526245D0
(en)
*
|
1995-12-21 |
1996-02-21 |
Celltech Therapeutics Ltd |
Chemical compounds
|
GB9526246D0
(en)
*
|
1995-12-21 |
1996-02-21 |
Celltech Therapeutics Ltd |
Chemical compounds
|
GB9608435D0
(en)
*
|
1996-04-24 |
1996-06-26 |
Celltech Therapeutics Ltd |
Chemical compounds
|
EP0812829A1
(en)
*
|
1996-06-14 |
1997-12-17 |
Ontogen Corporation |
Substituted imidazoles as modulators of multi-drug resistance
|
EP0812830A1
(en)
*
|
1996-06-14 |
1997-12-17 |
Ontogen Corporation |
Modulators of multi-drug resistances
|
GB9619284D0
(en)
*
|
1996-09-16 |
1996-10-30 |
Celltech Therapeutics Ltd |
Chemical compounds
|
GB9622363D0
(en)
|
1996-10-28 |
1997-01-08 |
Celltech Therapeutics Ltd |
Chemical compounds
|
GB9625184D0
(en)
*
|
1996-12-04 |
1997-01-22 |
Celltech Therapeutics Ltd |
Chemical compounds
|
US6057329A
(en)
*
|
1996-12-23 |
2000-05-02 |
Celltech Therapeutics Limited |
Fused polycyclic 2-aminopyrimidine derivatives
|
GB9705361D0
(en)
|
1997-03-14 |
1997-04-30 |
Celltech Therapeutics Ltd |
Chemical compounds
|
GB9713087D0
(en)
*
|
1997-06-20 |
1997-08-27 |
Celltech Therapeutics Ltd |
Chemical compounds
|
CO4940418A1
(es)
*
|
1997-07-18 |
2000-07-24 |
Novartis Ag |
Modificacion de cristal de un derivado de n-fenil-2- pirimidinamina, procesos para su fabricacion y su uso
|
GB9914258D0
(en)
|
1999-06-18 |
1999-08-18 |
Celltech Therapeutics Ltd |
Chemical compounds
|
CA2376957A1
(en)
|
1999-06-30 |
2001-01-04 |
Merck & Co., Inc. |
Src kinase inhibitor compounds
|
EP1194152A4
(en)
|
1999-06-30 |
2002-11-06 |
Merck & Co Inc |
SIN KINASE INHIBITOR COMPOUNDS
|
US6498165B1
(en)
|
1999-06-30 |
2002-12-24 |
Merck & Co., Inc. |
Src kinase inhibitor compounds
|
GB9919778D0
(en)
|
1999-08-21 |
1999-10-27 |
Zeneca Ltd |
Chemical compounds
|
ES2250186T3
(es)
|
1999-09-10 |
2006-04-16 |
MERCK & CO., INC. |
Inhibidores de tirosina quinasa.
|
GB9924862D0
(en)
|
1999-10-20 |
1999-12-22 |
Celltech Therapeutics Ltd |
Chemical compounds
|
WO2001060816A1
(en)
*
|
2000-02-17 |
2001-08-23 |
Amgen Inc. |
Kinase inhibitors
|
GB0004887D0
(en)
|
2000-03-01 |
2000-04-19 |
Astrazeneca Uk Ltd |
Chemical compounds
|
GB0004888D0
(en)
|
2000-03-01 |
2000-04-19 |
Astrazeneca Uk Ltd |
Chemical compounds
|
GB0004886D0
(en)
|
2000-03-01 |
2000-04-19 |
Astrazeneca Uk Ltd |
Chemical compounds
|
GB0004890D0
(en)
*
|
2000-03-01 |
2000-04-19 |
Astrazeneca Uk Ltd |
Chemical compounds
|
US7087608B2
(en)
*
|
2000-03-03 |
2006-08-08 |
Robert Charles Atkins |
Use of PDGF receptor tyrosine kinase inhibitors for the treatment of diabetic nephropathy
|
GB0007371D0
(en)
|
2000-03-28 |
2000-05-17 |
Astrazeneca Uk Ltd |
Chemical compounds
|
US7030219B2
(en)
|
2000-04-28 |
2006-04-18 |
Johns Hopkins University |
B7-DC, Dendritic cell co-stimulatory molecules
|
EP2277877A1
(en)
|
2000-08-18 |
2011-01-26 |
Millennium Pharmaceuticals, Inc. |
Quinazoline derivatives as kinase inhibitors
|
GB0022438D0
(en)
*
|
2000-09-13 |
2000-11-01 |
Novartis Ag |
Organic Compounds
|
CZ303944B6
(cs)
*
|
2000-10-27 |
2013-07-10 |
Novartis Ag |
Pouzití 4-(4-methylpiperazin-1-ylmethyl)-N-(4-methyl-3-((4-pyridin-3-yl)pyrimidin-2-ylamino)fenyl)benzamidu pri lécbe gastrointestinálních stromálních tumoru
|
EP1330444B1
(en)
|
2000-11-01 |
2011-03-23 |
Millennium Pharmaceuticals, Inc. |
Nitrogenous heterocyclic compounds and process for making them
|
GB0103926D0
(en)
*
|
2001-02-17 |
2001-04-04 |
Astrazeneca Ab |
Chemical compounds
|
SI3351246T1
(sl)
|
2001-02-19 |
2019-08-30 |
Novartis Pharma Ag |
Derivat rapamicina za zdravljenje trdnega tumorja, povezanega z deregulirano angiogenezo
|
SE0100569D0
(sv)
*
|
2001-02-20 |
2001-02-20 |
Astrazeneca Ab |
New compounds
|
DE60232719D1
(de)
|
2001-02-27 |
2009-08-06 |
Novartis Ag |
Kombination enthaltend einen inhibitor der signaltransduktion und ein epothilonderivat
|
US20040167134A1
(en)
|
2001-05-16 |
2004-08-26 |
Christian Bruns |
Combination comprising n-{5-[4-(4-methyl-piperazino-methyl)-benzoylamido]-2-methylphenyl}-4-(3-pyridyl)-2pyrimidine-amine and a chemotherapeutic agent
|
EP1721609A3
(en)
*
|
2001-05-16 |
2007-01-31 |
GPC Biotech AG |
Pyridylpyrimidine derivatives as effective compounds against prion diseases
|
EP2186901B1
(en)
|
2001-06-14 |
2015-06-03 |
The Regents of The University of California |
Mutations in the BCR-Abl-tyrosine kinase associated with resistance to STI-571
|
AU2002315388A1
(en)
|
2001-06-21 |
2003-01-08 |
Ariad Pharmaceuticals, Inc. |
Novel phenylamino-pyrimidines and uses thereof
|
EP1404672B1
(en)
|
2001-06-22 |
2006-01-18 |
Merck & Co., Inc. |
Tyrosine kinase inhibitors
|
EP1401415B1
(en)
|
2001-06-29 |
2006-06-21 |
AB Science |
Use of n-phenyl-2-pyrimidine-amine derivatives for treating inflammatory diseases
|
JP2004537542A
(ja)
|
2001-06-29 |
2004-12-16 |
アブ サイエンス |
炎症性腸疾患(ibd)を治療するための、チロシンキナーゼ阻害剤の使用
|
DK1401413T3
(da)
|
2001-06-29 |
2007-03-26 |
Ab Science |
Anvendelse af tyrosinkinaseinhibitorer til behandling af allergiske sygdomme
|
CA2452368A1
(en)
*
|
2001-06-29 |
2003-01-09 |
Ab Science |
New potent, selective and non toxic c-kit inhibitors
|
WO2003004006A2
(en)
*
|
2001-06-29 |
2003-01-16 |
Ab Science |
Use of potent, selective and non toxic c-kit inhibitors for treating tumor angiogenesis
|
US20060204459A1
(en)
*
|
2001-09-20 |
2006-09-14 |
Alain Moussy |
Use of tyrosine inhibitors for whitening human skin and treating melanocyted dysfunction associated diseases
|
WO2003040141A1
(en)
*
|
2001-09-28 |
2003-05-15 |
Bayer Pharmaceuticals Corporation |
Oxazolyl-phenyl-2,4-diamino-pyrimidine compounds and methods for treating hyperproliferative disorders
|
WO2003031608A2
(en)
|
2001-10-05 |
2003-04-17 |
Novartis Ag |
Mutated abl kinase domains
|
GB0201508D0
(en)
*
|
2002-01-23 |
2002-03-13 |
Novartis Ag |
Organic compounds
|
AU2007203463B2
(en)
*
|
2002-02-07 |
2010-12-23 |
Novartis Pharma Ag |
N-phenyl-2-pyrimidine-amine derivatives
|
GB0202873D0
(en)
|
2002-02-07 |
2002-03-27 |
Novartis Ag |
Organic compounds
|
GB0202874D0
(en)
*
|
2002-02-07 |
2002-03-27 |
Novartis Ag |
Organic compounds
|
ATE326970T1
(de)
*
|
2002-02-22 |
2006-06-15 |
Us Gov Veterans Affairs |
Verwendung von 4-(4-methylpiperazin-1-ylmethyl)-n 4-methyl-3-(4-pyridin-3-yl) pyrimidin-2-ylamino) phenyl benzamid zur behandlung von seminomen
|
CA2477726A1
(en)
*
|
2002-02-27 |
2003-09-04 |
Ab Science |
Use of tyrosine kinase inhibitors for treating substance use disorders
|
PT1478380E
(pt)
*
|
2002-02-27 |
2006-12-29 |
Ab Science |
Utilização de inibidores de tirosina-cinases para tratar doenças do snc
|
EP1480688A1
(en)
*
|
2002-02-28 |
2004-12-01 |
Novartis AG |
N-(5- 4-(4-methyl-piperazino-methyl)-benzoylamido)-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidine-amine coated stents
|
GB0206215D0
(en)
|
2002-03-15 |
2002-05-01 |
Novartis Ag |
Organic compounds
|
GB0209265D0
(en)
*
|
2002-04-23 |
2002-06-05 |
Novartis Ag |
Organic compounds
|
WO2003095448A1
(en)
*
|
2002-05-06 |
2003-11-20 |
Bayer Pharmaceuticals Corporation |
Pyridinyl amino pyrimidine derivatives useful for treating hyper-proliferative disorders
|
JP5227492B2
(ja)
|
2002-05-16 |
2013-07-03 |
ノバルティス アーゲー |
癌におけるedgレセプター結合剤の使用
|
US7015227B2
(en)
|
2002-06-21 |
2006-03-21 |
Cgi Pharmaceuticals, Inc. |
Certain amino-substituted monocycles as kinase modulators
|
WO2004026930A2
(en)
*
|
2002-06-26 |
2004-04-01 |
The Ohio State University Research Foundation |
The method for reducing inflammation using sti-571 or its salt
|
AU2003246100A1
(en)
*
|
2002-06-28 |
2004-01-19 |
Nippon Shinyaku Co., Ltd. |
Amide derivative
|
GB0215676D0
(en)
*
|
2002-07-05 |
2002-08-14 |
Novartis Ag |
Organic compounds
|
US6872724B2
(en)
|
2002-07-24 |
2005-03-29 |
Merck & Co., Inc. |
Polymorphs with tyrosine kinase activity
|
KR101036866B1
(ko)
*
|
2002-08-02 |
2011-05-25 |
에이비 사이언스 |
2-(3-아미노아릴)아미노-4-아릴-티아졸 및 c-kit억제제로서의 이의 용도
|
GB0222514D0
(en)
*
|
2002-09-27 |
2002-11-06 |
Novartis Ag |
Organic compounds
|
WO2004032925A1
(en)
*
|
2002-10-11 |
2004-04-22 |
Novartis Ag |
Use of imatinib (glivec, sti-571) to inhibit breast cancer resistance protein (bcrp)-mediated resistance to therapeutic agents
|
GB0224455D0
(en)
*
|
2002-10-21 |
2002-11-27 |
Novartis Ag |
Organic compounds
|
US7094785B1
(en)
|
2002-12-18 |
2006-08-22 |
Cornell Research Foundation, Inc. |
Method of treating polycythemia vera
|
US7144911B2
(en)
*
|
2002-12-31 |
2006-12-05 |
Deciphera Pharmaceuticals Llc |
Anti-inflammatory medicaments
|
GB2398565A
(en)
|
2003-02-18 |
2004-08-25 |
Cipla Ltd |
Imatinib preparation and salts
|
KR20060002933A
(ko)
*
|
2003-04-04 |
2006-01-09 |
베이코 테크 리미티드 |
혈관용 스텐트
|
AU2003232650A1
(en)
|
2003-05-06 |
2004-11-26 |
Il Yang Pharm Co., Ltd. |
N-phenyl-2-pyrimidine-amine derivatives and process for the preparation thereof
|
PE20050158A1
(es)
|
2003-05-19 |
2005-05-12 |
Irm Llc |
Compuestos inmunosupresores y composiciones
|
MY150088A
(en)
|
2003-05-19 |
2013-11-29 |
Irm Llc |
Immunosuppressant compounds and compositions
|
KR101102229B1
(ko)
*
|
2003-05-27 |
2012-01-05 |
닐스 리차드 웰쉬 |
당뇨병을 치료하기 위한 티로신 키나제 억제제의 용도
|
CN1805748B
(zh)
*
|
2003-06-13 |
2010-05-26 |
诺瓦提斯公司 |
作为raf激酶抑制剂的2-氨基嘧啶衍生物
|
CA2876822C
(en)
|
2003-08-27 |
2015-11-17 |
David Shima |
Combination therapy for the treatment of ocular neovascular disorders
|
DE602004020654D1
(de)
|
2003-11-18 |
2009-05-28 |
Novartis Ag |
Hemmer der mutanten form von kit
|
EP1702917B1
(en)
*
|
2003-12-25 |
2017-08-02 |
Nippon Shinyaku Co., Ltd. |
Amide derivative and medicine
|
CA2554201C
(en)
*
|
2004-01-21 |
2015-04-14 |
Emory University |
Compositions and use of tyrosine kinase inhibitors to treat pathogenic infection
|
PE20051096A1
(es)
|
2004-02-04 |
2006-01-23 |
Novartis Ag |
Formas de sal de 4-(4-metilpiperazin-1-ilmetil)-n-[4-metil-3-(4-piridin-3-il)pirimidin-2-ilamino)fenil]-benzamida
|
EP1720853B2
(en)
|
2004-02-11 |
2023-06-28 |
Natco Pharma Limited |
Pharmaceutical compositions of the 2 crystalline form of imatinib mesylate for use in the treatment of chronic myelogenous leukemia
|
CN1309719C
(zh)
*
|
2004-02-18 |
2007-04-11 |
陈国庆 |
苯氨基嘧啶衍生物及其用途
|
DK2253614T3
(da)
|
2004-04-07 |
2013-01-07 |
Novartis Ag |
IAP-inhibitorer
|
GB0512324D0
(en)
|
2005-06-16 |
2005-07-27 |
Novartis Ag |
Organic compounds
|
EP1786781A2
(en)
*
|
2004-08-27 |
2007-05-23 |
GPC Biotech AG |
Pyrimidine derivatives
|
US8269003B2
(en)
|
2004-09-02 |
2012-09-18 |
Cipla Limited |
Stable crystal form of imatinib mesylate and process for the preparation thereof
|
US8735415B2
(en)
|
2004-09-09 |
2014-05-27 |
Natco Pharma Limited |
Acid addition salts of (3,5-Bis trifluoromethyl)-N-[4-methyl-3-(4-pyridin-3yl-pyrimidin-2ylamino)-phenyl]-benzamide
|
US7939541B2
(en)
*
|
2004-09-09 |
2011-05-10 |
Natco Pharma Limited |
Intermediates and a process employing the intermediates for the preparation of (3-trifluoromethylsulfonyl)-N-[4-methyl-3-(4-pyridin-3yl-pyrimidin-2ylamino)-phenyl]-benzamide
|
CN101068805B
(zh)
|
2004-09-09 |
2013-04-03 |
纳科法尔马有限公司 |
作为bcr-abl激酶抑制剂的新的苯基氨基嘧啶衍生物
|
WO2006054314A1
(en)
*
|
2004-11-17 |
2006-05-26 |
Natco Pharma Limited |
Polymorphic forms of imatinib mesylate
|
SI1833815T1
(sl)
*
|
2004-12-30 |
2011-01-31 |
Inst Farmaceutyczny |
Postopek priprave baze imatiniba
|
CN1972917B
(zh)
*
|
2004-12-31 |
2010-08-25 |
孙飘扬 |
氨基嘧啶类化合物及其盐和其制备方法与药物用途
|
CN1939910A
(zh)
*
|
2004-12-31 |
2007-04-04 |
孙飘扬 |
氨基嘧啶类化合物及其盐和其制备方法与药物用途
|
WO2006077424A1
(en)
|
2005-01-21 |
2006-07-27 |
Astex Therapeutics Limited |
Pharmaceutical compounds
|
CA2606716C
(en)
|
2005-05-02 |
2013-07-23 |
Novartis Ag |
Use of pyrimidylaminobenzamide derivatives for the treatment of systematic mastocytosis
|
GB0510390D0
(en)
|
2005-05-20 |
2005-06-29 |
Novartis Ag |
Organic compounds
|
UA96139C2
(xx)
|
2005-11-08 |
2011-10-10 |
Дженентек, Інк. |
Антитіло до нейропіліну-1 (nrp1)$антитело к нейропилину-1 (nrp1)
|
NZ568182A
(en)
|
2005-11-21 |
2010-08-27 |
Novartis Ag |
Neuroendocrine tumor treatment using MTOR inhibitors
|
KR20130137721A
(ko)
|
2005-11-25 |
2013-12-17 |
노파르티스 아게 |
이마티니브 메실레이트의 f, g, h, i 및 k 결정형
|
GB0605120D0
(en)
|
2006-03-14 |
2006-04-26 |
Novartis Ag |
Organic Compounds
|
BRPI0709749A2
(pt)
|
2006-04-05 |
2011-07-26 |
Novartis Ag |
combinaÇÕes de agentes terapÊuticos para tratamento de cÂncer
|
AU2007240548A1
(en)
|
2006-04-05 |
2007-11-01 |
Novartis Ag |
Combinations of therapeutic agents for treating cancer
|
PE20110235A1
(es)
|
2006-05-04 |
2011-04-14 |
Boehringer Ingelheim Int |
Combinaciones farmaceuticas que comprenden linagliptina y metmorfina
|
EP2272511A1
(en)
|
2006-05-09 |
2011-01-12 |
Novartis AG |
Combination comprising an iron chelator and an anti-neoplastic agent and use thereof
|
US20060223817A1
(en)
*
|
2006-05-15 |
2006-10-05 |
Chemagis Ltd. |
Crystalline imatinib base and production process therefor
|
CA2651368A1
(en)
|
2006-06-01 |
2007-12-06 |
Japan As Represented By Director General Of Agency Of National Cancer Center |
Tumor suppressor
|
ATE502943T1
(de)
|
2006-09-29 |
2011-04-15 |
Novartis Ag |
Pyrazolopyrimidine als pi3k-lipidkinasehemmer
|
EP2073803B1
(en)
|
2006-10-12 |
2018-09-19 |
Astex Therapeutics Limited |
Pharmaceutical combinations
|
EP2073807A1
(en)
|
2006-10-12 |
2009-07-01 |
Astex Therapeutics Limited |
Pharmaceutical combinations
|
US20080207904A1
(en)
*
|
2006-10-26 |
2008-08-28 |
Macdonald Peter |
Imatinib base, and imatinib mesylate and processes for preparation thereof
|
BRPI0718812A2
(pt)
*
|
2006-11-16 |
2013-12-03 |
Italiana Sint Spa |
Processo para a preparação de imatinib e intermediários deste
|
CN101245061B
(zh)
*
|
2007-02-13 |
2012-09-19 |
天津天士力集团有限公司 |
N-(5-氨基-2-甲基苯基)-4-(3-吡啶基)-2-嘧啶胺类一氧化氮供体型衍生物,制备方法及其用途
|
AR065335A1
(es)
|
2007-02-15 |
2009-06-03 |
Novartis Ag |
Combinaciones de agentes terapeuticos para el tratamiento de cancer
|
RU2329260C1
(ru)
*
|
2007-02-20 |
2008-07-20 |
Юрий Иосифович Копырин |
Способ получения 2-анилинопиримидинов или их солей (варианты)
|
US20100087444A1
(en)
*
|
2007-03-12 |
2010-04-08 |
Dr. Reddy's Laboratories Ltd. |
Imatinib mesylate
|
WO2008117298A1
(en)
*
|
2007-03-26 |
2008-10-02 |
Natco Pharma Limited |
A novel method of preparation of imatinib
|
US7550591B2
(en)
|
2007-05-02 |
2009-06-23 |
Chemagis Ltd. |
Imatinib production process
|
WO2008136010A1
(en)
*
|
2007-05-07 |
2008-11-13 |
Natco Pharma Limited |
A process for the preparation of highly pure imatinib base
|
US9062023B2
(en)
|
2007-06-07 |
2015-06-23 |
Intra-Cellular Therapies, Inc. |
Heterocycle compounds and uses thereof
|
JP5710251B2
(ja)
|
2007-06-07 |
2015-04-30 |
イントラ−セルラー・セラピーズ・インコーポレイテッドIntra−Cellular Therapies, Inc. |
新規ヘテロ環化合物およびその使用
|
US8530480B2
(en)
*
|
2007-09-04 |
2013-09-10 |
The Scripps Research Institute |
Substituted pyrimidinyl-amines as protein kinase inhibitors
|
WO2009060463A1
(en)
*
|
2007-11-05 |
2009-05-14 |
Natco Pharma Limited |
An environmentally friendly process for the preparation of imatinib base
|
EP2062885A1
(en)
*
|
2007-11-21 |
2009-05-27 |
Eczacibasi-Zentiva Kimyasal Ürünler Sanayi ve Ticaret A.S. |
Acid addition salts of imatinib and formulations comprising the same
|
SI2252597T1
(sl)
*
|
2008-02-01 |
2014-07-31 |
Akinion Pharmaceuticals Ab |
Derivati pirazina in njihova uporaba kot inhibitorji protein kinaze
|
US8222424B2
(en)
|
2008-03-24 |
2012-07-17 |
Novartis Ag |
Arylsulfonamide-based matrix metalloprotease inhibitors
|
WO2009118305A1
(en)
|
2008-03-26 |
2009-10-01 |
Novartis Ag |
Hydroxamate-based inhibitors of deacetylases b
|
CN101584696A
(zh)
|
2008-05-21 |
2009-11-25 |
上海艾力斯医药科技有限公司 |
包含喹唑啉衍生物的组合物及制备方法、用途
|
NO2300013T3
(xx)
|
2008-05-21 |
2018-02-03 |
|
|
US9273077B2
(en)
|
2008-05-21 |
2016-03-01 |
Ariad Pharmaceuticals, Inc. |
Phosphorus derivatives as kinase inhibitors
|
PL215042B1
(pl)
*
|
2008-08-01 |
2013-10-31 |
Temapharm Spolka Z Ograniczona Odpowiedzialnoscia |
Sposób wytwarzania imatinibu
|
UY32030A
(es)
|
2008-08-06 |
2010-03-26 |
Boehringer Ingelheim Int |
"tratamiento para diabetes en pacientes inapropiados para terapia con metformina"
|
CN102123704B
(zh)
|
2008-08-15 |
2014-02-12 |
勃林格殷格翰国际有限公司 |
用于治疗fab-相关疾病的嘌呤衍生物
|
KR20110050529A
(ko)
|
2008-08-25 |
2011-05-13 |
앰플리뮨, 인크. |
Pd-1 길항제의 조성물 및 사용 방법
|
US20110223241A1
(en)
|
2008-10-16 |
2011-09-15 |
Celator Pharmaceuticals, Inc. |
Combination methods and compositions
|
EP2186514B1
(en)
|
2008-11-14 |
2016-06-29 |
Kinki University |
Treatment of Malignant Peripheral Nerve Sheath Tumors
|
RU2518114C3
(ru)
|
2008-12-18 |
2021-11-24 |
Новартис Аг |
Гемифумаратная соль 1-[4-[1-(4-циклогексил-3-трифторметилбензилоксиимино)этил]-2-этилбензил] азетидин-3-карбоновой кислоты
|
BRPI0922457A2
(pt)
|
2008-12-18 |
2015-12-15 |
Novartis Ag |
forma polimórfica de ácido 1-(4-{1-[(e)-4-ciclo-hexil-3-trifluormetil-benziloxi-imino]-etil)-2-etil-benzil)-azetidino-3-carboxílico"
|
KR20110101159A
(ko)
|
2008-12-18 |
2011-09-15 |
노파르티스 아게 |
신규 염
|
CN102256976A
(zh)
|
2008-12-23 |
2011-11-23 |
贝林格尔.英格海姆国际有限公司 |
有机化合物的盐形式
|
AR074990A1
(es)
|
2009-01-07 |
2011-03-02 |
Boehringer Ingelheim Int |
Tratamiento de diabetes en pacientes con un control glucemico inadecuado a pesar de la terapia con metformina
|
WO2010083617A1
(en)
|
2009-01-21 |
2010-07-29 |
Oncalis Ag |
Pyrazolopyrimidines as protein kinase inhibitors
|
TWI466672B
(zh)
|
2009-01-29 |
2015-01-01 |
Boehringer Ingelheim Int |
小兒科病人糖尿病之治療
|
US20110281917A1
(en)
|
2009-01-29 |
2011-11-17 |
Darrin Stuart |
Substituted Benzimidazoles for the Treatment of Astrocytomas
|
CN117547538A
(zh)
|
2009-02-13 |
2024-02-13 |
勃林格殷格翰国际有限公司 |
包含dpp-4抑制剂(利格列汀)任选地组合其它抗糖尿病药的抗糖尿病药物
|
WO2010099139A2
(en)
|
2009-02-25 |
2010-09-02 |
Osi Pharmaceuticals, Inc. |
Combination anti-cancer therapy
|
US8642834B2
(en)
|
2009-02-27 |
2014-02-04 |
OSI Pharmaceuticals, LLC |
Methods for the identification of agents that inhibit mesenchymal-like tumor cells or their formation
|
US8465912B2
(en)
|
2009-02-27 |
2013-06-18 |
OSI Pharmaceuticals, LLC |
Methods for the identification of agents that inhibit mesenchymal-like tumor cells or their formation
|
WO2010099138A2
(en)
|
2009-02-27 |
2010-09-02 |
Osi Pharmaceuticals, Inc. |
Methods for the identification of agents that inhibit mesenchymal-like tumor cells or their formation
|
UA103918C2
(xx)
|
2009-03-02 |
2013-12-10 |
Айерем Элелси |
N-(гетеро)арил, 2-(гетеро)арилзаміщені ацетаміди для застосування як модуляторів wnt передачі сигналу$n-(гетеро)арил, 2-(гетеро)арилзамещенные ацетамиды для применения как модуляторов wnt передачи сигнала
|
TW201102068A
(en)
|
2009-06-02 |
2011-01-16 |
Novartis Ag |
Treatment of ophthalmologic disorders mediated by alpha-carbonic anhydrase isoforms
|
CA2765983C
(en)
|
2009-06-26 |
2017-11-14 |
Novartis Ag |
1,3-disubstituted imidazolidin-2-one derivatives as inhibitors of cyp 17
|
WO2011014520A2
(en)
|
2009-07-29 |
2011-02-03 |
Irm Llc |
Compounds and compositions as modulators of gpr119 activity
|
US8389526B2
(en)
|
2009-08-07 |
2013-03-05 |
Novartis Ag |
3-heteroarylmethyl-imidazo[1,2-b]pyridazin-6-yl derivatives
|
AU2010283806A1
(en)
|
2009-08-12 |
2012-03-01 |
Novartis Ag |
Heterocyclic hydrazone compounds and their uses to treat cancer and inflammation
|
SG178454A1
(en)
|
2009-08-17 |
2012-03-29 |
Intellikine Inc |
Heterocyclic compounds and uses thereof
|
WO2011020861A1
(en)
|
2009-08-20 |
2011-02-24 |
Novartis Ag |
Heterocyclic oxime compounds
|
US20120149661A1
(en)
|
2009-08-26 |
2012-06-14 |
Novartis Ag |
Tetra-substituted heteroaryl compounds and their use as mdm2 and/or mdm4 modulators
|
WO2011029915A1
(en)
|
2009-09-10 |
2011-03-17 |
Novartis Ag |
Ether derivatives of bicyclic heteroaryls
|
CN107028924A
(zh)
|
2009-10-02 |
2017-08-11 |
勃林格殷格翰国际有限公司 |
包含bi‑1356和二甲双胍的药物组合物
|
CN102686579A
(zh)
|
2009-10-09 |
2012-09-19 |
Irm责任有限公司 |
作为gpr119活性调节剂的化合物和组合物
|
PL389357A1
(pl)
|
2009-10-22 |
2011-04-26 |
Tomasz Koźluk |
Sole imatinibu z pochodnymi kwasów winowych i sposób ich wytwarzania
|
CN102596951B
(zh)
|
2009-11-04 |
2015-04-15 |
诺华股份有限公司 |
用作mek抑制剂的杂环磺酰胺衍生物
|
EA201200617A1
(ru)
|
2009-11-23 |
2012-11-30 |
Серулин Фарма Инк. |
Полимеры на основе циклодекстрина для доставки лекарственных средств
|
EP2504339A1
(en)
|
2009-11-25 |
2012-10-03 |
Novartis AG |
Benzene-fused 6-membered oxygen-containing heterocyclic derivatives of bicyclic heteroaryls
|
ES2760917T3
(es)
|
2009-11-27 |
2020-05-18 |
Boehringer Ingelheim Int |
Tratamiento de pacientes diabéticos genotipificados con inhibidores DPP-IV como la linagliptina
|
US8394858B2
(en)
|
2009-12-03 |
2013-03-12 |
Novartis Ag |
Cyclohexane derivatives and uses thereof
|
JP5456908B2
(ja)
|
2009-12-08 |
2014-04-02 |
ノバルティス アーゲー |
ヘテロ環式スルホンアミド誘導体
|
WO2011070588A1
(en)
|
2009-12-10 |
2011-06-16 |
Arch Pharmalabs Limited |
Process for the preparation of imatinib and salts thereof
|
CU24130B1
(es)
|
2009-12-22 |
2015-09-29 |
Novartis Ag |
Isoquinolinonas y quinazolinonas sustituidas
|
US8440693B2
(en)
|
2009-12-22 |
2013-05-14 |
Novartis Ag |
Substituted isoquinolinones and quinazolinones
|
WO2011090940A1
(en)
|
2010-01-19 |
2011-07-28 |
Cerulean Pharma Inc. |
Cyclodextrin-based polymers for therapeutic delivery
|
JP2013519665A
(ja)
|
2010-02-15 |
2013-05-30 |
リライアンス ライフ サイエンシズ ピーヴィーティー リミティッド |
メシル酸イマチニブのα形の製造方法
|
PL390611A1
(pl)
|
2010-03-04 |
2011-09-12 |
Tomasz Koźluk |
Sposób otrzymywania polimorficznej formy alfa i nowa forma polimorficzna mesylanu imatinibu
|
CA2792472A1
(en)
|
2010-03-15 |
2011-09-22 |
Natco Pharma Limited |
Process for the preparation of highly pure crystalline imatinib base
|
JP2013522279A
(ja)
|
2010-03-18 |
2013-06-13 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
糖尿病及び関連状態の治療で用いるgpr119作動薬とddp−iv阻害薬リナグリプチンの組合せ
|
WO2011119995A2
(en)
|
2010-03-26 |
2011-09-29 |
Cerulean Pharma Inc. |
Formulations and methods of use
|
WO2011130918A1
(zh)
*
|
2010-04-23 |
2011-10-27 |
上海百灵医药科技有限公司 |
一种伊马替尼的合成方法
|
EP2382976A1
(en)
|
2010-04-30 |
2011-11-02 |
Hiroshima University |
Use of pdgf-r inhibitors for the treatment of lymph node metastasis of gastric cancer
|
CA2797310C
(en)
|
2010-05-05 |
2020-03-31 |
Boehringer Ingelheim International Gmbh |
Glp-1 receptor agonist and dpp-4 inhibitor combination therapy
|
CN102947274A
(zh)
|
2010-06-17 |
2013-02-27 |
诺瓦提斯公司 |
联苯基取代的1,3-二氢-苯并咪唑-2-亚基胺衍生物
|
CN102947275A
(zh)
|
2010-06-17 |
2013-02-27 |
诺瓦提斯公司 |
哌啶基取代的1,3-二氢-苯并咪唑-2-亚基胺衍生物
|
SI2582689T1
(sl)
|
2010-06-18 |
2017-05-31 |
Krka, D.D., Novo Mesto |
Nova polimorfna oblika imatinib baze in priprava njenih soli
|
PL234542B1
(pl)
*
|
2010-06-21 |
2020-03-31 |
Zakl Farmaceutyczne Polpharma Spolka Akcyjna |
Sposób otrzymywania kompozycji farmaceutycznej zawierającej imatinib lub jego farmaceutycznie dopuszczalną sól
|
EA201991014A1
(ru)
|
2010-06-24 |
2019-09-30 |
Бёрингер Ингельхайм Интернациональ Гмбх |
Лечение диабета
|
UA112517C2
(uk)
|
2010-07-06 |
2016-09-26 |
Новартіс Аг |
Тетрагідропіридопіримідинові похідні
|
WO2012006503A1
(en)
|
2010-07-09 |
2012-01-12 |
Genentech, Inc. |
Anti-neuropilin antibodies and methods of use
|
US8697739B2
(en)
|
2010-07-29 |
2014-04-15 |
Novartis Ag |
Bicyclic acetyl-CoA carboxylase inhibitors and uses thereof
|
WO2012019633A1
(en)
|
2010-08-11 |
2012-02-16 |
Synthon B.V. |
Pharmaceutical granulate comprising imatinib mesylate
|
TR201007005A2
(tr)
|
2010-08-23 |
2011-09-21 |
Mustafa Nevzat İlaç Sanayi̇i̇ A.Ş. |
İmatinib baz üretim yöntemi
|
US8946260B2
(en)
|
2010-09-16 |
2015-02-03 |
Novartis Ag |
17α-hydroxylase/C17,20-lyase inhibitors
|
US9034883B2
(en)
|
2010-11-15 |
2015-05-19 |
Boehringer Ingelheim International Gmbh |
Vasoprotective and cardioprotective antidiabetic therapy
|
TR201010618A2
(tr)
|
2010-12-20 |
2012-07-23 |
Bi̇lgi̇ç Mahmut |
İmatinib içeren bir oral dozaj formu ve bu oral dozaj formunun üretimi
|
CN103270026A
(zh)
|
2010-12-21 |
2013-08-28 |
诺瓦提斯公司 |
作为vps34抑制剂的联-杂芳基化合物
|
WO2012090221A1
(en)
|
2010-12-29 |
2012-07-05 |
Cadila Healthcare Limited |
Novel salts of imatinib
|
JP2014505088A
(ja)
|
2011-02-10 |
2014-02-27 |
ノバルティス アーゲー |
C−METチロシンキナーゼ阻害剤としての[1,2,4]トリアゾロ[4,3−b]ピリダジン化合物
|
US9127000B2
(en)
|
2011-02-23 |
2015-09-08 |
Intellikine, LLC. |
Heterocyclic compounds and uses thereof
|
US9295673B2
(en)
|
2011-02-23 |
2016-03-29 |
Intellikine Llc |
Combination of mTOR inhibitors and P13-kinase inhibitors, and uses thereof
|
CZ305457B6
(cs)
|
2011-02-28 |
2015-09-30 |
Ústav organické chemie a biochemie, Akademie věd ČR v. v. i. |
Pyrimidinové sloučeniny inhibující tvorbu oxidu dusnatého a prostaglandinu E2, způsob výroby a použití
|
WO2012120469A1
(en)
|
2011-03-08 |
2012-09-13 |
Novartis Ag |
Fluorophenyl bicyclic heteroaryl compounds
|
PL394169A1
(pl)
|
2011-03-09 |
2012-09-10 |
Adamed Spółka Z Ograniczoną Odpowiedzialnością |
Kompozycja farmaceutyczna metanosulfonianu imatinibu do napełniania jednostkowych postaci dawkowania oraz sposób jej wytwarzania
|
EP2508525A1
(en)
|
2011-04-05 |
2012-10-10 |
Bayer Pharma Aktiengesellschaft |
Substituted 2,3-dihydroimidazo[1,2-c]quinazoline salts
|
US9896730B2
(en)
|
2011-04-25 |
2018-02-20 |
OSI Pharmaceuticals, LLC |
Use of EMT gene signatures in cancer drug discovery, diagnostics, and treatment
|
WO2012149413A1
(en)
|
2011-04-28 |
2012-11-01 |
Novartis Ag |
17α-HYDROXYLASE/C17,20-LYASE INHIBITORS
|
CN103501612B
(zh)
|
2011-05-04 |
2017-03-29 |
阿里亚德医药股份有限公司 |
抑制表皮生长因子受体导致的癌症中细胞增殖的化合物
|
CN102796110B
(zh)
*
|
2011-05-23 |
2016-03-30 |
复旦大学 |
苯胺嘧啶化合物及其制备方法和用途
|
BR112013031201A2
(pt)
|
2011-06-09 |
2017-01-31 |
Novartis Ag |
derivados de sulfonamida heterocíclicos, composição farmacêutica os compreendendo, uso, processo para a fabricação de (r)-n-(4,5-difluoro-6-((2-fluoro-4-iodofenil)amino)benzofuran-7-il)-1-(2,3-di-idroxipropil)ciclopropano-5 1-sulfonamida e kit
|
US8859535B2
(en)
|
2011-06-20 |
2014-10-14 |
Novartis Ag |
Hydroxy substituted isoquinolinone derivatives
|
EP2721007B1
(en)
|
2011-06-20 |
2015-04-29 |
Novartis AG |
Cyclohexyl isoquinolinone compounds
|
US9750700B2
(en)
|
2011-06-22 |
2017-09-05 |
Natco Pharma Limited |
Imatinib mesylate oral pharmaceutical composition and process for preparation thereof
|
CN103608349A
(zh)
|
2011-06-27 |
2014-02-26 |
诺瓦提斯公司 |
四氢-吡啶并-嘧啶衍生物的固体形式和盐
|
ITMI20111309A1
(it)
|
2011-07-14 |
2013-01-15 |
Italiana Sint Spa |
Procedimento di preparazione di imatinib mesilato
|
EA030121B1
(ru)
|
2011-07-15 |
2018-06-29 |
Бёрингер Ингельхайм Интернациональ Гмбх |
Замещенные хиназолины, их получение и их применение в фармацевтических композициях
|
WO2013035102A1
(en)
|
2011-09-05 |
2013-03-14 |
Natco Pharma Limited |
Processes for the preparation of imatinib base and intermediates thereof
|
US9062045B2
(en)
|
2011-09-15 |
2015-06-23 |
Novartis Ag |
Triazolopyridine compounds
|
WO2013067157A1
(en)
|
2011-11-01 |
2013-05-10 |
Modgene, Llc |
Compositions and methods for reduction of amyloid-beta load
|
RU2486180C1
(ru)
*
|
2011-11-02 |
2013-06-27 |
Общество с ограниченной ответственностью "ТехноХим" (ООО "ТехноХим") |
Способ получения 2-ариламино-4-гетарилпиримидинов
|
US8969341B2
(en)
|
2011-11-29 |
2015-03-03 |
Novartis Ag |
Pyrazolopyrrolidine compounds
|
US9408885B2
(en)
|
2011-12-01 |
2016-08-09 |
Vib Vzw |
Combinations of therapeutic agents for treating melanoma
|
CN103159739A
(zh)
*
|
2011-12-09 |
2013-06-19 |
天津市国际生物医药联合研究院有限公司 |
1,4-二取代-1,2,3-三氮唑类化合物及其制备方法
|
JO3398B1
(ar)
|
2011-12-22 |
2019-10-20 |
Novartis Ag |
مشتقات 2،3- ثانى هيدرو- بنزو[1,4] أوكسازين والمركبات المتعلقة بها كمثبطات كيناز فسفواينوسيتيد-3 (pi3k) لمعالجة على سبيل المثال التهاب المفاصل الروماتيدي
|
WO2013093850A1
(en)
|
2011-12-22 |
2013-06-27 |
Novartis Ag |
Quinoline derivatives
|
AU2012355613A1
(en)
|
2011-12-23 |
2014-07-17 |
Novartis Ag |
Compounds for inhibiting the interaction of BCL2 with binding partners
|
US20130178520A1
(en)
|
2011-12-23 |
2013-07-11 |
Duke University |
Methods of treatment using arylcyclopropylamine compounds
|
MX2014007730A
(es)
|
2011-12-23 |
2015-01-12 |
Novartis Ag |
Compuestos para inhibir la interaccion de bcl2 con los componentes de enlace.
|
KR20140107578A
(ko)
|
2011-12-23 |
2014-09-04 |
노파르티스 아게 |
Bcl2와 결합 파트너의 상호작용을 억제하기 위한 화합물
|
KR20140107575A
(ko)
|
2011-12-23 |
2014-09-04 |
노파르티스 아게 |
Bcl2와 결합 파트너의 상호작용을 억제하기 위한 화합물
|
AU2012355624A1
(en)
|
2011-12-23 |
2014-07-17 |
Novartis Ag |
Compounds for inhibiting the interaction of BCL2 with binding partners
|
US20130172244A1
(en)
|
2011-12-29 |
2013-07-04 |
Thomas Klein |
Subcutaneous therapeutic use of dpp-4 inhibitor
|
PL226174B1
(pl)
|
2011-12-30 |
2017-06-30 |
Inst Farm |
Polaczenie analogu witaminy D z imatinibem do stosowania w leczeniu skojarzonym niedrobnokomorkowego raka pluc
|
UY34591A
(es)
|
2012-01-26 |
2013-09-02 |
Novartis Ag |
Compuestos de imidazopirrolidinona
|
GB2514285B
(en)
|
2012-02-13 |
2018-07-18 |
Grindeks Jsc |
Intermediates for a novel process of preparing imatinib and related tyrosine kinase inhibitors
|
IN2012DE00728A
(xx)
|
2012-03-13 |
2015-08-21 |
Fresenius Kabi Oncology Ltd |
|
CN110507654A
(zh)
|
2012-04-03 |
2019-11-29 |
诺华有限公司 |
有酪氨酸激酶抑制剂的组合产品和其应用
|
WO2013152252A1
(en)
|
2012-04-06 |
2013-10-10 |
OSI Pharmaceuticals, LLC |
Combination anti-cancer therapy
|
CA2871453A1
(en)
|
2012-04-24 |
2013-10-31 |
Chugai Seiyaku Kabushiki Kaisha |
Quinazolinedione derivative
|
AR090836A1
(es)
|
2012-04-24 |
2014-12-10 |
Chugai Pharmaceutical Co Ltd |
Derivados de benzamida
|
AU2013204563B2
(en)
|
2012-05-05 |
2016-05-19 |
Takeda Pharmaceutical Company Limited |
Compounds for inhibiting cell proliferation in EGFR-driven cancers
|
US20130303462A1
(en)
|
2012-05-14 |
2013-11-14 |
Boehringer Ingelheim International Gmbh |
Use of a dpp-4 inhibitor in podocytes related disorders and/or nephrotic syndrome
|
US20130303554A1
(en)
|
2012-05-14 |
2013-11-14 |
Boehringer Ingelheim International Gmbh |
Use of a dpp-4 inhibitor in sirs and/or sepsis
|
WO2013174767A1
(en)
|
2012-05-24 |
2013-11-28 |
Boehringer Ingelheim International Gmbh |
A xanthine derivative as dpp -4 inhibitor for use in modifying food intake and regulating food preference
|
JP6374862B2
(ja)
|
2012-05-24 |
2018-08-15 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
自己免疫性糖尿病、特に、ladaの治療に使用するためのdpp−4阻害剤としてのキサンチン誘導体
|
WO2013175417A1
(en)
|
2012-05-24 |
2013-11-28 |
Novartis Ag |
Pyrrolopyrrolidinone compounds
|
BR112014031421A2
(pt)
|
2012-06-15 |
2017-06-27 |
Brigham & Womens Hospital Inc |
composições para tratamento de câncer e métodos para produção das mesmas
|
WO2014016848A2
(en)
|
2012-07-24 |
2014-01-30 |
Laurus Labs Private Limited |
Solid forms of tyrosine kinase inhibitors, process for the preparation and their pharmaceutical composition thereof
|
US9738643B2
(en)
|
2012-08-06 |
2017-08-22 |
Duke University |
Substituted indazoles for targeting Hsp90
|
WO2014041551A1
(en)
|
2012-09-14 |
2014-03-20 |
Natco Pharma Limited |
Formulation comprising imatinib as oral solution
|
CN103664787B
(zh)
|
2012-09-17 |
2015-09-09 |
南京圣和药业股份有限公司 |
炔杂芳环化合物及其应用
|
WO2014052619A1
(en)
|
2012-09-27 |
2014-04-03 |
Irm Llc |
Piperidine derivatives and compositions as modulators of gpr119 activity
|
EP2902028A1
(en)
|
2012-09-28 |
2015-08-05 |
Hangzhou Bensheng Pharmaceutical Co., Ltd. |
Drug composition for treating tumors and application thereof
|
WO2014055938A1
(en)
*
|
2012-10-04 |
2014-04-10 |
Inhibikase Therapeutics, Inc. |
Novel compounds, their preparation and their uses
|
US9950047B2
(en)
|
2012-11-05 |
2018-04-24 |
Dana-Farber Cancer Institute, Inc. |
XBP1, CD138, and CS1 peptides, pharmaceutical compositions that include the peptides, and methods of using such peptides and compositions
|
TW201422625A
(zh)
|
2012-11-26 |
2014-06-16 |
Novartis Ag |
二氫-吡啶并-□衍生物之固體形式
|
CN103848812B
(zh)
*
|
2012-12-04 |
2016-08-03 |
北大方正集团有限公司 |
精制伊马替尼的方法
|
CN103044394A
(zh)
*
|
2012-12-20 |
2013-04-17 |
北京理工大学 |
一种苯基氨基嘧啶衍生物及其制备方法和用途
|
EP2749271A1
(en)
|
2012-12-31 |
2014-07-02 |
Deva Holding Anonim Sirketi |
Optimized manufacturing method and pharmaceutical formulation of imatinib
|
US9556180B2
(en)
|
2013-01-22 |
2017-01-31 |
Novartis Ag |
Pyrazolo[3,4-d]pyrimidinone compounds as inhibitors of the P53/MDM2 interaction
|
EP2948451B1
(en)
|
2013-01-22 |
2017-07-12 |
Novartis AG |
Substituted purinone compounds
|
WO2014124860A1
(en)
|
2013-02-14 |
2014-08-21 |
Boehringer Ingelheim International Gmbh |
Specific pde4b-inhibitors for the treatment of diabetes mellitus
|
SG11201505896YA
(en)
|
2013-02-20 |
2015-09-29 |
Novartis Ag |
Treatment of cancer using humanized anti-egfrviii chimeric antigen receptor
|
WO2014128612A1
(en)
|
2013-02-20 |
2014-08-28 |
Novartis Ag |
Quinazolin-4-one derivatives
|
CA2906542A1
(en)
|
2013-03-15 |
2014-09-25 |
Intellikine, Llc |
Combination of kinase inhibitors and uses thereof
|
EA037712B1
(ru)
|
2013-03-15 |
2021-05-13 |
Бёрингер Ингельхайм Интернациональ Гмбх |
Кардио- и нефропротективная противодиабетическая терапия
|
WO2014155268A2
(en)
|
2013-03-25 |
2014-10-02 |
Novartis Ag |
Fgf-r tyrosine kinase activity inhibitors - use in diseases associated with lack of or reduced snf5 activity
|
US9611283B1
(en)
|
2013-04-10 |
2017-04-04 |
Ariad Pharmaceuticals, Inc. |
Methods for inhibiting cell proliferation in ALK-driven cancers
|
EP2803353B1
(en)
|
2013-05-14 |
2018-05-23 |
Hetero Research Foundation |
Compositions of Imatinib
|
US20150018376A1
(en)
|
2013-05-17 |
2015-01-15 |
Novartis Ag |
Pyrimidin-4-yl)oxy)-1h-indole-1-carboxamide derivatives and use thereof
|
UY35675A
(es)
|
2013-07-24 |
2015-02-27 |
Novartis Ag |
Derivados sustituidos de quinazolin-4-ona
|
WO2015022663A1
(en)
|
2013-08-14 |
2015-02-19 |
Novartis Ag |
Compounds and compositions as inhibitors of mek
|
US9227969B2
(en)
|
2013-08-14 |
2016-01-05 |
Novartis Ag |
Compounds and compositions as inhibitors of MEK
|
WO2015022664A1
(en)
|
2013-08-14 |
2015-02-19 |
Novartis Ag |
Compounds and compositions as inhibitors of mek
|
SG11201600028YA
(en)
|
2013-09-22 |
2016-02-26 |
Calitor Sciences Llc |
Substituted aminopyrimidine compounds and methods of use
|
AU2014336016B2
(en)
|
2013-10-17 |
2019-12-19 |
Sartar Therapeutics Ltd |
Compositions comprising phosphodiesterase inhibitors for use in the treatment of a solid tumor in a human patient
|
CN105829285A
(zh)
|
2013-10-23 |
2016-08-03 |
中外制药株式会社 |
喹唑啉酮和异喹啉酮衍生物
|
TW201605450A
(zh)
|
2013-12-03 |
2016-02-16 |
諾華公司 |
Mdm2抑制劑與BRAF抑制劑之組合及其用途
|
US10000469B2
(en)
|
2014-03-25 |
2018-06-19 |
Duke University |
Heat shock protein 70 (hsp-70) receptor ligands
|
WO2015145388A2
(en)
|
2014-03-27 |
2015-10-01 |
Novartis Ag |
Methods of treating colorectal cancers harboring upstream wnt pathway mutations
|
EP3327006B1
(en)
|
2014-03-28 |
2020-05-20 |
Calitor Sciences, LLC |
Substituted heteroaryl compounds and methods of use
|
AU2015241198A1
(en)
|
2014-04-03 |
2016-11-17 |
Invictus Oncology Pvt. Ltd. |
Supramolecular combinatorial therapeutics
|
US9630944B2
(en)
|
2014-04-04 |
2017-04-25 |
F.I.S.—Fabbrica Italiana Sintetici S.p.A. |
Process for preparing Imatinib and salts thereof, free of genotoxic impurity F
|
US20170027940A1
(en)
|
2014-04-10 |
2017-02-02 |
Stichting Het Nederlands Kanker Instituut |
Method for treating cancer
|
WO2016011658A1
(en)
|
2014-07-25 |
2016-01-28 |
Novartis Ag |
Combination therapy
|
KR20170036037A
(ko)
|
2014-07-31 |
2017-03-31 |
노파르티스 아게 |
조합 요법
|
WO2016059220A1
(en)
|
2014-10-16 |
2016-04-21 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Tcr-activating agents for use in the treatment of t-all
|
CN105585556A
(zh)
*
|
2014-11-13 |
2016-05-18 |
连云港杰瑞药业有限公司 |
一种伊马替尼的合成方法
|
EP3347097B1
(en)
|
2015-09-11 |
2021-02-24 |
Sunshine Lake Pharma Co., Ltd. |
Substituted aminopyrimidine derivatives as modulators of the kinases jak, flt3 and aurora
|
EA035891B1
(ru)
|
2016-01-25 |
2020-08-27 |
КРКА, д.д., НОВО МЕСТО |
Быстродиспергируемая фармацевтическая композиция, включающая ингибитор тирозинкиназы
|
CN108883108B
(zh)
|
2016-03-25 |
2021-08-06 |
Ab科学有限公司 |
马赛替尼用于治疗肌萎缩侧索硬化症患者亚群的用途
|
US11261187B2
(en)
|
2016-04-22 |
2022-03-01 |
Duke University |
Compounds and methods for targeting HSP90
|
EP4233840A3
(en)
|
2016-06-10 |
2023-10-18 |
Boehringer Ingelheim International GmbH |
Combinations of linagliptin and metformin
|
EP3257499A1
(en)
|
2016-06-17 |
2017-12-20 |
Vipharm S.A. |
Process for preparation of imatinib methanesulfonate capsules
|
CN107652269A
(zh)
*
|
2016-07-26 |
2018-02-02 |
江苏豪森药业集团有限公司 |
甲磺酸氟马替尼中间体纯化方法
|
WO2018039203A1
(en)
|
2016-08-23 |
2018-03-01 |
Oncopep, Inc. |
Peptide vaccines and durvalumab for treating multiple myeloma
|
EP3503914A1
(en)
|
2016-08-23 |
2019-07-03 |
Oncopep, Inc. |
Peptide vaccines and durvalumab for treating breast cancer
|
CN107805240A
(zh)
*
|
2016-09-08 |
2018-03-16 |
中国科学院合肥物质科学研究院 |
一种新型的pdgfr激酶抑制剂及其用途
|
CA3035080A1
(en)
|
2016-09-27 |
2018-04-05 |
Cero Therapeutics, Inc. |
Chimeric engulfment receptor molecules
|
US10927083B2
(en)
|
2016-09-29 |
2021-02-23 |
Duke University |
Substituted benzimidazoles as inhibitors of transforming growth factor-β kinase
|
US10207998B2
(en)
|
2016-09-29 |
2019-02-19 |
Duke University |
Substituted benzimidazole and substituted benzothiazole inhibitors of transforming growth factor-β kinase and methods of use thereof
|
EP3333162A1
(en)
|
2016-12-12 |
2018-06-13 |
Silesian Catalysts sp. z o.o. |
Metod for preparing n-(2-methyl-5-nitrophenyl)-4-(pyridin-3-yl)pyrimidin-2-amine
|
CN107089969B
(zh)
*
|
2017-04-26 |
2020-04-24 |
黑龙江鑫创生物科技开发有限公司 |
一种合成伊马替尼中间体的方法
|
RU2020114641A
(ru)
|
2017-09-26 |
2021-10-27 |
Серо Терапьютикс, Инк. |
Молекулы химерных интернализационных рецепторов и способы применения
|
WO2019083960A1
(en)
|
2017-10-24 |
2019-05-02 |
Oncopep, Inc. |
PEPTIDE VACCINES AND HDAC INHIBITORS FOR THE TREATMENT OF MULTIPLE MYELOMA
|
US20200276304A1
(en)
|
2017-10-24 |
2020-09-03 |
Oncopep, Inc. |
Peptide vaccines and pembrolizumab for treating breast cancer
|
US10683297B2
(en)
|
2017-11-19 |
2020-06-16 |
Calitor Sciences, Llc |
Substituted heteroaryl compounds and methods of use
|
EP3730483B1
(en)
|
2017-12-21 |
2023-08-30 |
Hefei Institutes of Physical Science, Chinese Academy of Sciences |
Class of pyrimidine derivative kinase inhibitors
|
US10751339B2
(en)
|
2018-01-20 |
2020-08-25 |
Sunshine Lake Pharma Co., Ltd. |
Substituted aminopyrimidine compounds and methods of use
|
EP3774869A1
(en)
|
2018-03-28 |
2021-02-17 |
Cero Therapeutics, Inc. |
Expression vectors for chimeric engulfment receptors, genetically modified host cells, and uses thereof
|
EP3774865A1
(en)
|
2018-03-28 |
2021-02-17 |
Cero Therapeutics, Inc. |
Cellular immunotherapy compositions and uses thereof
|
US20210087251A1
(en)
|
2018-03-28 |
2021-03-25 |
Cero Therapeutics, Inc. |
Chimeric tim4 receptors and uses thereof
|
KR20210035227A
(ko)
|
2018-07-17 |
2021-03-31 |
베링거 인겔하임 인터내셔날 게엠베하 |
심장 안전성 및 신장 안전성 항당뇨 치료법
|
CA3103992A1
(en)
|
2018-07-17 |
2020-01-23 |
Boehringer Ingelheim International Gmbh |
Cardiosafe antidiabetic therapy
|
EP3826988A4
(en)
|
2018-07-24 |
2023-03-22 |
Hygia Pharmaceuticals, LLC |
COMPOUNDS, DERIVATIVES AND ANALOGS AGAINST CANCER
|
WO2021009686A1
(en)
|
2019-07-15 |
2021-01-21 |
Intas Pharmaceuticals Ltd. |
Pharmaceutical composition of imatinib
|
US20240058446A1
(en)
|
2019-10-03 |
2024-02-22 |
Cero Therapeutics, Inc. |
Chimeric tim4 receptors and uses thereof
|
EP4058465A1
(en)
|
2019-11-14 |
2022-09-21 |
Cohbar Inc. |
Cxcr4 antagonist peptides
|
WO2021233534A1
(en)
|
2020-05-20 |
2021-11-25 |
Pvac Medical Technologies Ltd |
Use of substance and pharmaceutical composition thereof, and medical treatments or uses thereof
|
WO2021185844A1
(en)
|
2020-03-16 |
2021-09-23 |
Pvac Medical Technologies Ltd |
Use of substance and pharmaceutical composition thereof, and medical treatments or uses thereof
|
WO2021228983A1
(en)
|
2020-05-13 |
2021-11-18 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
A pharmaceutical composition comprising an arsenic compound, an inductor of type-1 ifn and a protein kinase inhibitor for treating cancer
|
EP4192509A1
(en)
|
2020-08-05 |
2023-06-14 |
Ellipses Pharma Ltd |
Treatment of cancer using a cyclodextrin-containing polymer-topoisomerase inhibitor conjugate and a parp inhibitor
|
WO2022036287A1
(en)
|
2020-08-14 |
2022-02-17 |
Cero Therapeutics, Inc. |
Anti-cd72 chimeric receptors and uses thereof
|
WO2022036285A1
(en)
|
2020-08-14 |
2022-02-17 |
Cero Therapeutics, Inc. |
Compositions and methods for treating cancer with chimeric tim receptors in combination with inhibitors of poly (adp-ribose) polymerase
|
WO2022036265A1
(en)
|
2020-08-14 |
2022-02-17 |
Cero Therapeutics, Inc. |
Chimeric tim receptors and uses thereof
|
US11999964B2
(en)
|
2020-08-28 |
2024-06-04 |
California Institute Of Technology |
Synthetic mammalian signaling circuits for robust cell population control
|
TW202237638A
(zh)
|
2020-12-09 |
2022-10-01 |
日商武田藥品工業股份有限公司 |
烏苷酸環化酶c(gcc)抗原結合劑之組成物及其使用方法
|
CN117203223A
(zh)
|
2021-02-26 |
2023-12-08 |
凯洛尼亚疗法有限公司 |
淋巴细胞靶向慢病毒载体
|
EP4376874A1
(en)
|
2021-07-28 |
2024-06-05 |
Cero Therapeutics, Inc. |
Chimeric tim4 receptors and uses thereof
|
WO2024030441A1
(en)
|
2022-08-02 |
2024-02-08 |
National University Corporation Hokkaido University |
Methods of improving cellular therapy with organelle complexes
|