US5521184A
(en)
*
|
1992-04-03 |
1996-05-28 |
Ciba-Geigy Corporation |
Pyrimidine derivatives and processes for the preparation thereof
|
GB9212673D0
(en)
*
|
1992-06-15 |
1992-07-29 |
Celltech Ltd |
Chemical compounds
|
US5972598A
(en)
*
|
1992-09-17 |
1999-10-26 |
Board Of Trustess Of The University Of Illinois |
Methods for preventing multidrug resistance in cancer cells
|
US6171786B1
(en)
|
1992-09-17 |
2001-01-09 |
Board Of Trustees Of University Of Illinois |
Methods for preventing multidrug resistance in cancer cells
|
GB9222253D0
(en)
*
|
1992-10-23 |
1992-12-09 |
Celltech Ltd |
Chemical compounds
|
GB9304919D0
(en)
*
|
1993-03-10 |
1993-04-28 |
Celltech Ltd |
Chemical compounds
|
GB9304920D0
(en)
*
|
1993-03-10 |
1993-04-28 |
Celltech Ltd |
Chemical compounds
|
US5543520A
(en)
*
|
1993-10-01 |
1996-08-06 |
Ciba-Geigy Corporation |
Pyrimidine derivatives
|
PT672042E
(en)
*
|
1993-10-01 |
2006-08-31 |
Novartis Ag |
Pharmacologically active pyrimidineamine derivatives and processes for their preparation
|
CA2148931A1
(en)
*
|
1993-10-01 |
1995-04-13 |
Jurg Zimmermann |
Pyrimidineamine derivatives and processes for the preparation thereof
|
PL179417B1
(en)
*
|
1993-10-01 |
2000-09-29 |
Novartis Ag |
Pharmacologically active derivatives of pyridine and methods of obtaining them
|
GB9325217D0
(en)
*
|
1993-12-09 |
1994-02-09 |
Zeneca Ltd |
Pyrimidine derivatives
|
GB9326600D0
(en)
*
|
1993-12-22 |
1994-03-02 |
Celltech Ltd |
Chemical compounds
|
ATE260911T1
(en)
*
|
1993-12-22 |
2004-03-15 |
Celltech R&D Ltd |
TRISUBSUTITUTED PHENYL DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE AS PHOSPHODIESTERASE (TYPE IV) INHIBITORS
|
US5786354A
(en)
*
|
1994-06-21 |
1998-07-28 |
Celltech Therapeutics, Limited |
Tri-substituted phenyl derivatives and processes for their preparation
|
US6245774B1
(en)
|
1994-06-21 |
2001-06-12 |
Celltech Therapeutics Limited |
Tri-substituted phenyl or pyridine derivatives
|
GB9412573D0
(en)
*
|
1994-06-22 |
1994-08-10 |
Celltech Ltd |
Chemical compounds
|
GB9412571D0
(en)
*
|
1994-06-22 |
1994-08-10 |
Celltech Ltd |
Chemical compounds
|
GB9412672D0
(en)
*
|
1994-06-23 |
1994-08-10 |
Celltech Ltd |
Chemical compounds
|
US5756527A
(en)
*
|
1995-06-07 |
1998-05-26 |
Ontogen Corporation |
Imidazole derivatives useful as modulators of multi drug resistances
|
GB9523675D0
(en)
|
1995-11-20 |
1996-01-24 |
Celltech Therapeutics Ltd |
Chemical compounds
|
GB9526245D0
(en)
*
|
1995-12-21 |
1996-02-21 |
Celltech Therapeutics Ltd |
Chemical compounds
|
GB9526246D0
(en)
*
|
1995-12-21 |
1996-02-21 |
Celltech Therapeutics Ltd |
Chemical compounds
|
GB9608435D0
(en)
*
|
1996-04-24 |
1996-06-26 |
Celltech Therapeutics Ltd |
Chemical compounds
|
EP0812829A1
(en)
*
|
1996-06-14 |
1997-12-17 |
Ontogen Corporation |
Substituted imidazoles as modulators of multi-drug resistance
|
EP0812830A1
(en)
*
|
1996-06-14 |
1997-12-17 |
Ontogen Corporation |
Modulators of multi-drug resistances
|
GB9619284D0
(en)
*
|
1996-09-16 |
1996-10-30 |
Celltech Therapeutics Ltd |
Chemical compounds
|
GB9622363D0
(en)
*
|
1996-10-28 |
1997-01-08 |
Celltech Therapeutics Ltd |
Chemical compounds
|
GB9625184D0
(en)
*
|
1996-12-04 |
1997-01-22 |
Celltech Therapeutics Ltd |
Chemical compounds
|
JP2001507349A
(en)
|
1996-12-23 |
2001-06-05 |
セルテック セラピューティックス リミテッド |
Fused polycyclic 2-aminopyrimidine derivatives, their preparation and their use as protein tyrosine kinase inhibitors
|
GB9705361D0
(en)
*
|
1997-03-14 |
1997-04-30 |
Celltech Therapeutics Ltd |
Chemical compounds
|
GB9713087D0
(en)
*
|
1997-06-20 |
1997-08-27 |
Celltech Therapeutics Ltd |
Chemical compounds
|
CO4940418A1
(en)
*
|
1997-07-18 |
2000-07-24 |
Novartis Ag |
MODIFICATION OF A CRYSTAL OF A DERIVATIVE OF N-PHENYL-2-PIRIMIDINAMINE, PROCESSES FOR ITS MANUFACTURE AND USE
|
GB9914258D0
(en)
|
1999-06-18 |
1999-08-18 |
Celltech Therapeutics Ltd |
Chemical compounds
|
AU6605200A
(en)
|
1999-06-30 |
2001-01-31 |
Merck & Co., Inc. |
Src kinase inhibitor compounds
|
US6498165B1
(en)
|
1999-06-30 |
2002-12-24 |
Merck & Co., Inc. |
Src kinase inhibitor compounds
|
CA2376951A1
(en)
|
1999-06-30 |
2001-01-04 |
Peter J. Sinclair |
Src kinase inhibitor compounds
|
GB9919778D0
(en)
|
1999-08-21 |
1999-10-27 |
Zeneca Ltd |
Chemical compounds
|
BR0013899A
(en)
|
1999-09-10 |
2003-07-08 |
Merck & Co Inc |
A compound, pharmaceutical composition, processes for treating or preventing cancer, a disease in which angiogenesis is implicated, retinal vascularization, diabetic retinopathy, age-related macular degeneration, inflammatory diseases, tyrosine-dependent disease or conditions. kinase, bone-associated pathologies, and processes for producing a pharmaceutical composition, and for reducing or preventing tissue damage following a cerebral ischemic event
|
GB9924862D0
(en)
|
1999-10-20 |
1999-12-22 |
Celltech Therapeutics Ltd |
Chemical compounds
|
WO2001060816A1
(en)
*
|
2000-02-17 |
2001-08-23 |
Amgen Inc. |
Kinase inhibitors
|
GB0004886D0
(en)
|
2000-03-01 |
2000-04-19 |
Astrazeneca Uk Ltd |
Chemical compounds
|
GB0004888D0
(en)
|
2000-03-01 |
2000-04-19 |
Astrazeneca Uk Ltd |
Chemical compounds
|
GB0004890D0
(en)
*
|
2000-03-01 |
2000-04-19 |
Astrazeneca Uk Ltd |
Chemical compounds
|
GB0004887D0
(en)
|
2000-03-01 |
2000-04-19 |
Astrazeneca Uk Ltd |
Chemical compounds
|
US7087608B2
(en)
|
2000-03-03 |
2006-08-08 |
Robert Charles Atkins |
Use of PDGF receptor tyrosine kinase inhibitors for the treatment of diabetic nephropathy
|
GB0007371D0
(en)
|
2000-03-28 |
2000-05-17 |
Astrazeneca Uk Ltd |
Chemical compounds
|
US7030219B2
(en)
|
2000-04-28 |
2006-04-18 |
Johns Hopkins University |
B7-DC, Dendritic cell co-stimulatory molecules
|
KR100831116B1
(en)
|
2000-08-18 |
2008-05-20 |
밀레니엄 파머슈티컬스 인코퍼레이티드 |
Quinazoline derivatives as kinase inhibitors
|
GB0022438D0
(en)
*
|
2000-09-13 |
2000-11-01 |
Novartis Ag |
Organic Compounds
|
WO2002034727A2
(en)
*
|
2000-10-27 |
2002-05-02 |
Novartis Ag |
Treatment of gastrointestinal stromal tumors
|
JP4564713B2
(en)
|
2000-11-01 |
2010-10-20 |
ミレニアム・ファーマシューティカルズ・インコーポレイテッド |
Nitrogen heterocyclic compounds, and methods for making nitrogen heterocyclic compounds and intermediates thereof
|
GB0103926D0
(en)
*
|
2001-02-17 |
2001-04-04 |
Astrazeneca Ab |
Chemical compounds
|
PT3351246T
(en)
|
2001-02-19 |
2019-06-07 |
Novartis Pharma Ag |
Rapamycin derivative for the treatment of a solid tumor associated with deregulated angiogenesis
|
SE0100569D0
(en)
*
|
2001-02-20 |
2001-02-20 |
Astrazeneca Ab |
New compounds
|
WO2002067941A2
(en)
|
2001-02-27 |
2002-09-06 |
Novartis Ag |
Combination comprising a signal transduction inhibitor and an epothilone derivative
|
PL392652A1
(en)
|
2001-05-16 |
2010-12-06 |
Novartis Ag |
A combination consisting of N-{5-[4-(4-methyl-piperazine-methyl)-benzoiloamido]-2-methylphenyl} -4-(3-pyridyl)-2-pyrimidine-amine and the chemotherapeutic agent, the use thereof, pharmaceutical composition containing thereof a kit containing such a combination
|
CA2446939C
(en)
*
|
2001-05-16 |
2005-08-02 |
Matthias Stein-Gerlach |
Pyridylpyrimidine derivatives as effective compounds against prion diseases
|
WO2002102976A2
(en)
|
2001-06-14 |
2002-12-27 |
The Regents Of The University Of California |
Mutations in the bcr-abl tyrosine kinase associated with resistance to sti-571
|
WO2003000186A2
(en)
|
2001-06-21 |
2003-01-03 |
Ariad Pharmaceuticals, Inc. |
Novel phenylamino-pyrimidines and uses thereof
|
JP2004535437A
(en)
|
2001-06-22 |
2004-11-25 |
メルク エンド カムパニー インコーポレーテッド |
Tyrosine kinase inhibitor
|
JP2004537542A
(en)
|
2001-06-29 |
2004-12-16 |
アブ サイエンス |
Use of a tyrosine kinase inhibitor for treating inflammatory bowel disease (IBD)
|
JP2005500041A
(en)
|
2001-06-29 |
2005-01-06 |
アブ サイエンス |
Potent, selective and non-toxic C-KIT inhibitor
|
CA2452366A1
(en)
*
|
2001-06-29 |
2003-01-16 |
Ab Science |
Use of potent, selective and non toxic c-kit inhibitors for treating tumor angiogenesis
|
DE60212627T2
(en)
|
2001-06-29 |
2007-06-14 |
Ab Science |
Use of tyrosine kinase inhibitors for the treatment of inflammatory diseases
|
EP1401413B1
(en)
|
2001-06-29 |
2006-11-22 |
AB Science |
Use of tyrosine kinase inhibitions for treating allergic diseases
|
WO2003039550A1
(en)
*
|
2001-09-20 |
2003-05-15 |
Ab Science |
Use of tyrosine kinase inhibitors for whitening human skin and treating melanocyte dysfunction associated diseases
|
WO2003040141A1
(en)
*
|
2001-09-28 |
2003-05-15 |
Bayer Pharmaceuticals Corporation |
Oxazolyl-phenyl-2,4-diamino-pyrimidine compounds and methods for treating hyperproliferative disorders
|
EP2343365A1
(en)
|
2001-10-05 |
2011-07-13 |
Novartis AG |
Mutated Abl kinase domains
|
GB0201508D0
(en)
*
|
2002-01-23 |
2002-03-13 |
Novartis Ag |
Organic compounds
|
GB0202874D0
(en)
*
|
2002-02-07 |
2002-03-27 |
Novartis Ag |
Organic compounds
|
GB0202873D0
(en)
*
|
2002-02-07 |
2002-03-27 |
Novartis Ag |
Organic compounds
|
AU2007203462B2
(en)
*
|
2002-02-07 |
2011-01-06 |
Novartis Pharma Ag |
N-phenyl-2-pyrimidine-amine derivatives
|
DE60305460D1
(en)
*
|
2002-02-22 |
2006-06-29 |
Us Government |
USE OF 4- (4-METHYLPIPERAZINE-1-YLMETHYL) -N 4-METHYL-3- (4-PYRIDIN-3-YL) PYRIMIDIN-2-YLAMINO) PHENYL BENZAMIDE FOR THE TREATMENT OF SEMINOMES
|
WO2003072106A2
(en)
*
|
2002-02-27 |
2003-09-04 |
Ab Science |
Use of tyrosine kinase inhibitors for treating substance use disorders
|
PT1478380E
(en)
*
|
2002-02-27 |
2006-12-29 |
Ab Science |
Use of tyrosine kinase inhibitors for treating cns disorders
|
BR0308053A
(en)
*
|
2002-02-28 |
2004-12-28 |
Novartis Ag |
N- {5- [4- (4-Methyl-piperazine-methyl) -benzoylamido] -2-methyl-phenyl} -4- (3-pyridyl) -2-pyrimidine-amine-coated stents
|
GB0206215D0
(en)
|
2002-03-15 |
2002-05-01 |
Novartis Ag |
Organic compounds
|
GB0209265D0
(en)
*
|
2002-04-23 |
2002-06-05 |
Novartis Ag |
Organic compounds
|
AU2003231231A1
(en)
*
|
2002-05-06 |
2003-11-11 |
Bayer Pharmaceuticals Corporation |
Pyridinyl amino pyrimidine derivatives useful for treating hyper-proliferative disorders
|
EP1944026B1
(en)
|
2002-05-16 |
2013-06-26 |
Novartis AG |
Use of EDG receptor binding agents in cancer
|
US7015227B2
(en)
|
2002-06-21 |
2006-03-21 |
Cgi Pharmaceuticals, Inc. |
Certain amino-substituted monocycles as kinase modulators
|
WO2004026930A2
(en)
*
|
2002-06-26 |
2004-04-01 |
The Ohio State University Research Foundation |
The method for reducing inflammation using sti-571 or its salt
|
BRPI0312288B8
(en)
*
|
2002-06-28 |
2021-05-25 |
Nippon Shinyaku Co Ltd |
amide derivatives
|
GB0215676D0
(en)
*
|
2002-07-05 |
2002-08-14 |
Novartis Ag |
Organic compounds
|
US6872724B2
(en)
|
2002-07-24 |
2005-03-29 |
Merck & Co., Inc. |
Polymorphs with tyrosine kinase activity
|
BRPI0313165B8
(en)
*
|
2002-08-02 |
2021-05-25 |
Ab Science |
2-(3-aminoaryl)amino-4-aryl-thiazoles and their use as c-kit inhibitors
|
GB0222514D0
(en)
|
2002-09-27 |
2002-11-06 |
Novartis Ag |
Organic compounds
|
JP2006504721A
(en)
*
|
2002-10-11 |
2006-02-09 |
ノバルティス アクチエンゲゼルシャフト |
Use of Imatinib (Gleevec, STI-571) to inhibit breast cancer resistance protein (BCRP) -mediated resistance to therapeutic agents
|
GB0224455D0
(en)
*
|
2002-10-21 |
2002-11-27 |
Novartis Ag |
Organic compounds
|
US7094785B1
(en)
|
2002-12-18 |
2006-08-22 |
Cornell Research Foundation, Inc. |
Method of treating polycythemia vera
|
US7144911B2
(en)
*
|
2002-12-31 |
2006-12-05 |
Deciphera Pharmaceuticals Llc |
Anti-inflammatory medicaments
|
GB2398565A
(en)
*
|
2003-02-18 |
2004-08-25 |
Cipla Ltd |
Imatinib preparation and salts
|
BR0318237A
(en)
*
|
2003-04-04 |
2006-04-04 |
Bayco Tech Ltd |
vascular probe
|
AU2003232650A1
(en)
*
|
2003-05-06 |
2004-11-26 |
Il Yang Pharm Co., Ltd. |
N-phenyl-2-pyrimidine-amine derivatives and process for the preparation thereof
|
CA2524048C
(en)
|
2003-05-19 |
2013-06-25 |
Irm Llc |
Immunosuppressant compounds and compositions
|
MY150088A
(en)
|
2003-05-19 |
2013-11-29 |
Irm Llc |
Immunosuppressant compounds and compositions
|
WO2004105763A2
(en)
*
|
2003-05-27 |
2004-12-09 |
Haegerkvist Robert Per |
Use of tyrosine kinase inhibitor to treat diabetes
|
EP1635835B1
(en)
*
|
2003-06-13 |
2010-01-06 |
Novartis AG |
2-aminopyrimidine derivatives as raf kinase inhibitors
|
ES2388138T3
(en)
|
2003-08-27 |
2012-10-09 |
Ophthotech Corporation |
Combination therapy for the treatment of ocular neovascular disorders
|
ES2324917T3
(en)
|
2003-11-18 |
2009-08-19 |
Novartis Ag |
INHIBITORS OF THE MUTANT FORM OF KIT.
|
KR100848067B1
(en)
|
2003-12-25 |
2008-07-23 |
니뽄 신야쿠 가부시키가이샤 |
Amide derivative and medicine
|
EP2233174B1
(en)
*
|
2004-01-21 |
2016-07-20 |
Emory University |
Compositions and use of tyrosine kinase inhibitors to treat pathogenic infection
|
PE20051096A1
(en)
|
2004-02-04 |
2006-01-23 |
Novartis Ag |
SALT FORMS OF 4- (4-METHYLPIPERAZIN-1-ILMETHYL) -N- [4-METHYL-3- (4-PYRIDIN-3-IL) PYRIMIDIN-2-ILAMINO) PHENYL] -BENZAMIDE
|
PL1720853T3
(en)
*
|
2004-02-11 |
2016-06-30 |
Natco Pharma Ltd |
Novel polymorphic form of imatinib mesylate and a process for its preparation
|
CN1309719C
(en)
*
|
2004-02-18 |
2007-04-11 |
陈国庆 |
Derivative of phenylamide pyrimidine and application thereof
|
DK2253614T3
(en)
|
2004-04-07 |
2013-01-07 |
Novartis Ag |
IAP inhibitors
|
GB0512324D0
(en)
|
2005-06-16 |
2005-07-27 |
Novartis Ag |
Organic compounds
|
JP2008510766A
(en)
*
|
2004-08-27 |
2008-04-10 |
ゲーペーツェー ビオテック アーゲー |
Pyrimidine derivatives
|
KR101348625B1
(en)
|
2004-09-02 |
2014-01-07 |
씨아이피엘에이 엘티디. |
Stable crystal form of imatinib mesylate and process for the preparation thereof
|
US7939541B2
(en)
*
|
2004-09-09 |
2011-05-10 |
Natco Pharma Limited |
Intermediates and a process employing the intermediates for the preparation of (3-trifluoromethylsulfonyl)-N-[4-methyl-3-(4-pyridin-3yl-pyrimidin-2ylamino)-phenyl]-benzamide
|
US8735415B2
(en)
|
2004-09-09 |
2014-05-27 |
Natco Pharma Limited |
Acid addition salts of (3,5-Bis trifluoromethyl)-N-[4-methyl-3-(4-pyridin-3yl-pyrimidin-2ylamino)-phenyl]-benzamide
|
AP2470A
(en)
|
2004-09-09 |
2012-09-17 |
Natco Pharma Ltd |
Novel phenylaminopyrimidine derivatives as inhibitors of BCR-ABL kinase
|
WO2006054314A1
(en)
*
|
2004-11-17 |
2006-05-26 |
Natco Pharma Limited |
Polymorphic forms of imatinib mesylate
|
SI1833815T1
(en)
*
|
2004-12-30 |
2011-01-31 |
Inst Farmaceutyczny |
A process for preparation of imatinib base
|
CN1939910A
(en)
*
|
2004-12-31 |
2007-04-04 |
孙飘扬 |
Amino-metadiazine compound and its salt, its preparation and pharmaceutical use
|
CN1972917B
(en)
*
|
2004-12-31 |
2010-08-25 |
孙飘扬 |
Aminopyrimidine compounds and their salts, process for preparation and pharmaceutical use thereof
|
US20080161251A1
(en)
|
2005-01-21 |
2008-07-03 |
Astex Therapeutics Limited |
Pharmaceutical Compounds
|
CN103638028A
(en)
|
2005-05-02 |
2014-03-19 |
诺瓦提斯公司 |
Use of pyrimidylamimobenzamide derivatives for the treatment of systematic mastocytosis
|
GB0510390D0
(en)
|
2005-05-20 |
2005-06-29 |
Novartis Ag |
Organic compounds
|
UA96139C2
(en)
|
2005-11-08 |
2011-10-10 |
Дженентек, Інк. |
Anti-neuropilin-1 (nrp1) antibody
|
CA2629245C
(en)
|
2005-11-21 |
2016-07-12 |
Novartis Ag |
Neuroendocrine tumor treatment
|
US7893076B2
(en)
|
2005-11-25 |
2011-02-22 |
Novartis Ag |
Crystalline form F of Imatinib mesylate
|
GB0605120D0
(en)
|
2006-03-14 |
2006-04-26 |
Novartis Ag |
Organic Compounds
|
EP2606890A1
(en)
|
2006-04-05 |
2013-06-26 |
Novartis AG |
Combinations comprising BCR-ABL/C-KIT/PDGF-R TK inhibitors for treating cancer
|
CN101415409B
(en)
|
2006-04-05 |
2012-12-05 |
诺瓦提斯公司 |
Combinations of therapeutic agents for treating cancer
|
PE20080251A1
(en)
|
2006-05-04 |
2008-04-25 |
Boehringer Ingelheim Int |
USES OF DPP IV INHIBITORS
|
CN101443002B
(en)
|
2006-05-09 |
2012-03-21 |
诺瓦提斯公司 |
Combination comprising an iron chelator and an anti-neoplastic agent and use thereof
|
US20060223817A1
(en)
*
|
2006-05-15 |
2006-10-05 |
Chemagis Ltd. |
Crystalline imatinib base and production process therefor
|
AU2006345660A1
(en)
|
2006-06-01 |
2007-12-06 |
Japan As Represented By Director General Of Agency Of National Cancer Center |
Tumor suppressor
|
WO2008037477A1
(en)
|
2006-09-29 |
2008-04-03 |
Novartis Ag |
Pyrazolopyrimidines as p13k lipid kinase inhibitors
|
EP2073807A1
(en)
|
2006-10-12 |
2009-07-01 |
Astex Therapeutics Limited |
Pharmaceutical combinations
|
US8916552B2
(en)
|
2006-10-12 |
2014-12-23 |
Astex Therapeutics Limited |
Pharmaceutical combinations
|
US20080103305A1
(en)
*
|
2006-10-26 |
2008-05-01 |
Macdonald Peter |
Process for the preparation of imatinib
|
US8168787B2
(en)
|
2006-11-16 |
2012-05-01 |
F.I.S. Fabbrica Italiana Sintetici S.P.A. |
Process for the preparation of imatinib and intermediates thereof
|
CN101245061B
(en)
*
|
2007-02-13 |
2012-09-19 |
天津天士力集团有限公司 |
N-(5-amido-2-methyl phenyl)-4-(3-pyridinyl)-2-aminopyrimidine nitric oxide donating derivant, production method and uses thereof
|
CN101626758A
(en)
|
2007-02-15 |
2010-01-13 |
诺瓦提斯公司 |
Combinations of therapeutic agents for treating cancer
|
RU2329260C1
(en)
*
|
2007-02-20 |
2008-07-20 |
Юрий Иосифович Копырин |
Method of obtaining 2-anilinopyrimidines or their salts (options)
|
BRPI0808840A2
(en)
*
|
2007-03-12 |
2014-09-02 |
Reddy S Laborartories Ltd Dr |
IMATINIB MESILATE
|
WO2008117298A1
(en)
*
|
2007-03-26 |
2008-10-02 |
Natco Pharma Limited |
A novel method of preparation of imatinib
|
US7550591B2
(en)
|
2007-05-02 |
2009-06-23 |
Chemagis Ltd. |
Imatinib production process
|
WO2008136010A1
(en)
*
|
2007-05-07 |
2008-11-13 |
Natco Pharma Limited |
A process for the preparation of highly pure imatinib base
|
WO2008153959A1
(en)
|
2007-06-07 |
2008-12-18 |
Intra-Cellular Therapies, Inc. |
Novel heterocycle compounds and uses thereof
|
JP5559043B2
(en)
|
2007-06-07 |
2014-07-23 |
イントラ−セルラー・セラピーズ・インコーポレイテッド |
Novel heterocyclic compounds and uses thereof
|
ES2535166T3
(en)
*
|
2007-09-04 |
2015-05-06 |
The Scripps Research Institute |
Substituted pyrimidinyl amines as protein kinase inhibitors
|
WO2009060463A1
(en)
*
|
2007-11-05 |
2009-05-14 |
Natco Pharma Limited |
An environmentally friendly process for the preparation of imatinib base
|
EP2062885A1
(en)
*
|
2007-11-21 |
2009-05-27 |
Eczacibasi-Zentiva Kimyasal Ürünler Sanayi ve Ticaret A.S. |
Acid addition salts of imatinib and formulations comprising the same
|
MX2010007973A
(en)
*
|
2008-02-01 |
2010-11-09 |
Akinion Pharmaceuticals Ab |
Pyrazine derivatives and their use as protein kinase inhbitors.
|
MX2010010525A
(en)
|
2008-03-24 |
2010-10-25 |
Novartis Ag |
Arylsulfonamide-based matrix metalloprotease inhibitors.
|
EP2260020B1
(en)
|
2008-03-26 |
2014-07-23 |
Novartis AG |
Hydroxamate-based inhibitors of deacetylases b
|
CN101584696A
(en)
|
2008-05-21 |
2009-11-25 |
上海艾力斯医药科技有限公司 |
Composition containing quinazoline derivatives, preparation method and use
|
US9273077B2
(en)
|
2008-05-21 |
2016-03-01 |
Ariad Pharmaceuticals, Inc. |
Phosphorus derivatives as kinase inhibitors
|
CA2723961C
(en)
|
2008-05-21 |
2017-03-21 |
Ariad Pharmaceuticals, Inc. |
Phosphorous derivatives as kinase inhibitors
|
PL215042B1
(en)
*
|
2008-08-01 |
2013-10-31 |
Temapharm Spolka Z Ograniczona Odpowiedzialnoscia |
Method of imatinib manufacturing
|
UY32030A
(en)
|
2008-08-06 |
2010-03-26 |
Boehringer Ingelheim Int |
"TREATMENT FOR DIABETES IN INAPPROPRIATE PATIENTS FOR THERAPY WITH METFORMIN"
|
WO2010018217A2
(en)
|
2008-08-15 |
2010-02-18 |
Boehringer Ingelheim International Gmbh |
Organic compounds for wound healing
|
NZ591130A
(en)
|
2008-08-25 |
2012-09-28 |
Amplimmune Inc |
Compositions comprising a PD-1 antagonists and cyclophosphamide and methods of use thereof
|
EP2344161B1
(en)
|
2008-10-16 |
2018-12-19 |
Celator Pharmaceuticals, Inc. |
Combinations of a liposomal water-soluble camptothecin with cetuximab or bevacizumab
|
EP2186514B1
(en)
|
2008-11-14 |
2016-06-29 |
Kinki University |
Treatment of Malignant Peripheral Nerve Sheath Tumors
|
JP2012512884A
(en)
|
2008-12-18 |
2012-06-07 |
ノバルティス アーゲー |
Novel polymorphic form of 1- (4- {1-[(E) -4-cyclohexyl-3-trifluoromethyl-benzyloxyimino] -ethyl} -2-ethyl-benzyl) -azetidine-3-carboxylic acid
|
DK2676953T3
(en)
|
2008-12-18 |
2017-07-03 |
Novartis Ag |
Hemifumarate salt of 1- [4- [1- (4-cyclohexyl-3-trifluoromethyl-benzyloxyimino) -ethyl] -2-ethyl-benzyl] -acetidine-3-carboxylic acid for use in the treatment of lymphocyte-mediated diseases
|
MX2011006622A
(en)
|
2008-12-18 |
2011-07-12 |
Novartis Ag |
New salts.
|
CN107011345A
(en)
|
2008-12-23 |
2017-08-04 |
勃林格殷格翰国际有限公司 |
The salt form of organic compound
|
AR074990A1
(en)
|
2009-01-07 |
2011-03-02 |
Boehringer Ingelheim Int |
TREATMENT OF DIABETES IN PATIENTS WITH AN INAPPROPRIATE GLUCEMIC CONTROL THROUGH METFORMIN THERAPY
|
WO2010083617A1
(en)
|
2009-01-21 |
2010-07-29 |
Oncalis Ag |
Pyrazolopyrimidines as protein kinase inhibitors
|
TWI466672B
(en)
|
2009-01-29 |
2015-01-01 |
Boehringer Ingelheim Int |
Treatment for diabetes in paediatric patients
|
DK2391366T3
(en)
|
2009-01-29 |
2013-01-07 |
Novartis Ag |
Substituted benzimidazoles for the treatment of astrocytomas
|
EA029759B1
(en)
|
2009-02-13 |
2018-05-31 |
Бёрингер Ингельхайм Интернациональ Гмбх |
Antidiabetic medications comprising dpp-4 inhibitor (linagliptin) optionally in combination with other antidiabetic agents
|
US20120189641A1
(en)
|
2009-02-25 |
2012-07-26 |
OSI Pharmaceuticals, LLC |
Combination anti-cancer therapy
|
WO2010099363A1
(en)
|
2009-02-27 |
2010-09-02 |
Osi Pharmaceuticals, Inc. |
Methods for the identification of agents that inhibit mesenchymal-like tumor cells or their formation
|
WO2010099138A2
(en)
|
2009-02-27 |
2010-09-02 |
Osi Pharmaceuticals, Inc. |
Methods for the identification of agents that inhibit mesenchymal-like tumor cells or their formation
|
JP2012519282A
(en)
|
2009-02-27 |
2012-08-23 |
オーエスアイ・ファーマシューティカルズ,エルエルシー |
Methods for identifying mesenchymal tumor cells or agents that inhibit their production
|
UA103918C2
(en)
|
2009-03-02 |
2013-12-10 |
Айерем Элелси |
N-(hetero)aryl, 2-(hetero)aryl-substituted acetamides for use as wnt signaling modulators
|
TW201102068A
(en)
|
2009-06-02 |
2011-01-16 |
Novartis Ag |
Treatment of ophthalmologic disorders mediated by alpha-carbonic anhydrase isoforms
|
DK2445903T3
(en)
|
2009-06-26 |
2014-06-23 |
Novartis Ag |
1,3-Disubstituted imidazolidin-2-one derivatives as CYP17 inhibitors
|
WO2011014520A2
(en)
|
2009-07-29 |
2011-02-03 |
Irm Llc |
Compounds and compositions as modulators of gpr119 activity
|
US8389526B2
(en)
|
2009-08-07 |
2013-03-05 |
Novartis Ag |
3-heteroarylmethyl-imidazo[1,2-b]pyridazin-6-yl derivatives
|
AU2010283806A1
(en)
|
2009-08-12 |
2012-03-01 |
Novartis Ag |
Heterocyclic hydrazone compounds and their uses to treat cancer and inflammation
|
JP5819831B2
(en)
|
2009-08-17 |
2015-11-24 |
インテリカイン, エルエルシー |
Heterocyclic compounds and their use
|
KR20120089463A
(en)
|
2009-08-20 |
2012-08-10 |
노파르티스 아게 |
Heterocyclic oxime compounds
|
IN2012DN01693A
(en)
|
2009-08-26 |
2015-06-05 |
Novartis Ag |
|
CN102596963A
(en)
|
2009-09-10 |
2012-07-18 |
诺瓦提斯公司 |
Ether derivatives of bicyclic heteroaryls
|
KR101763659B1
(en)
|
2009-10-02 |
2017-08-01 |
베링거 인겔하임 인터내셔날 게엠베하 |
Pharmaceutical compositions comprising BI-1356 and metformin
|
US8575168B2
(en)
|
2009-10-09 |
2013-11-05 |
Irm Llc |
Compounds and compositions as modulators of GPR119 activity
|
PL389357A1
(en)
|
2009-10-22 |
2011-04-26 |
Tomasz Koźluk |
Tartaric acids derivatives imatinib salts and process for the preparation thereof
|
BR112012010519A2
(en)
|
2009-11-04 |
2017-12-05 |
Novartis Ag |
heterocyclic sulfonamide derivatives
|
CN102781237A
(en)
|
2009-11-23 |
2012-11-14 |
天蓝制药公司 |
Cyclodextrin-based polymers for therapeutic delivery
|
JP2013512215A
(en)
|
2009-11-25 |
2013-04-11 |
ノバルティス アーゲー |
Benzene condensed 6-membered oxygen-containing heterocyclic derivatives of bicyclic heteroaryl
|
EP3646859A1
(en)
|
2009-11-27 |
2020-05-06 |
Boehringer Ingelheim International GmbH |
Treatment of genotyped diabetic patients with dpp-iv inhibitors such as linagliptin
|
US8394858B2
(en)
|
2009-12-03 |
2013-03-12 |
Novartis Ag |
Cyclohexane derivatives and uses thereof
|
EA201200823A1
(en)
|
2009-12-08 |
2013-02-28 |
Новартис Аг |
HETEROCYCLIC DERIVATIVES OF SULPHONAMIDES
|
US20110306763A1
(en)
|
2009-12-10 |
2011-12-15 |
Shanghai Parling Pharmatech Co., Ltd. |
Process for the preparation of imatinib and salts thereof
|
CU24130B1
(en)
|
2009-12-22 |
2015-09-29 |
Novartis Ag |
ISOQUINOLINONES AND REPLACED QUINAZOLINONES
|
US8440693B2
(en)
|
2009-12-22 |
2013-05-14 |
Novartis Ag |
Substituted isoquinolinones and quinazolinones
|
US20110178287A1
(en)
|
2010-01-19 |
2011-07-21 |
Cerulean Pharma Inc. |
Cyclodextrin-based polymers for therapeutic delivery
|
CA2789989A1
(en)
|
2010-02-15 |
2011-08-18 |
Reliance Life Sciences Pvt. Ltd. |
Process for the preparation of alpha form of imatinib mesylate
|
PL390611A1
(en)
|
2010-03-04 |
2011-09-12 |
Tomasz Koźluk |
Process for the preparation of polymorphic alpha form and new polymorphic form of imatinib mesylate
|
WO2011114337A1
(en)
|
2010-03-15 |
2011-09-22 |
Natco Pharma Limited |
Process for the preparation of highly pure crystalline imatinib base
|
US20130109703A1
(en)
|
2010-03-18 |
2013-05-02 |
Boehringer Ingelheim International Gmbh |
Combination of a GPR119 Agonist and the DPP-IV Inhibitor Linagliptin for Use in the Treatment of Diabetes and Related Conditions
|
WO2011119995A2
(en)
|
2010-03-26 |
2011-09-29 |
Cerulean Pharma Inc. |
Formulations and methods of use
|
US8609842B2
(en)
*
|
2010-04-23 |
2013-12-17 |
Fujian South Pharmaceutical Co., Ltd. |
Method for synthesizing Imatinib
|
EP2382976A1
(en)
|
2010-04-30 |
2011-11-02 |
Hiroshima University |
Use of pdgf-r inhibitors for the treatment of lymph node metastasis of gastric cancer
|
AU2011249722B2
(en)
|
2010-05-05 |
2015-09-17 |
Boehringer Ingelheim International Gmbh |
Combination therapy
|
WO2011157787A1
(en)
|
2010-06-17 |
2011-12-22 |
Novartis Ag |
Biphenyl substituted 1,3-dihydro-benzoimidazol-2-ylideneamine derivatives
|
US20130085161A1
(en)
|
2010-06-17 |
2013-04-04 |
Novartis Ag |
Piperidinyl substituted 1,3-dihydro-benzoimidazol-2-ylideneamine derivatives
|
EA024088B1
(en)
|
2010-06-18 |
2016-08-31 |
КРКА, д.д., НОВО МЕСТО |
Alpha-form of imatinib mesylate, processes for preparation thereof and pharmaceutical composition comprising the same
|
EA029416B1
(en)
*
|
2010-06-21 |
2018-03-30 |
Заклады Фармацеутицне Польфарма Са |
Tablet comprising imatinib or a pharmaceutically acceptable salt thereof and process for the preparation thereof
|
BR112012032579B1
(en)
|
2010-06-24 |
2021-05-11 |
Boehringer Ingelheim International Gmbh |
use of linagliptin and pharmaceutical composition comprising linagliptin and long-acting basal insulin
|
UA112517C2
(en)
|
2010-07-06 |
2016-09-26 |
Новартіс Аг |
TETRAHYDROPYRIDOPYRIMIDINE DERIVATIVES
|
NZ605449A
(en)
|
2010-07-09 |
2015-03-27 |
Genentech Inc |
Anti-neuropilin antibodies and methods of use
|
US8697739B2
(en)
|
2010-07-29 |
2014-04-15 |
Novartis Ag |
Bicyclic acetyl-CoA carboxylase inhibitors and uses thereof
|
MX2013001653A
(en)
|
2010-08-11 |
2013-05-22 |
Synthon Bv |
Pharmaceutical granulate comprising imatinib mesylate
|
TR201007005A2
(en)
|
2010-08-23 |
2011-09-21 |
Mustafa Nevzat İlaç Sanayi̇i̇ A.Ş. |
Imatinib base production method
|
WO2012035078A1
(en)
|
2010-09-16 |
2012-03-22 |
Novartis Ag |
17α-HYDROXYLASE/C17,20-LYASE INHIBITORS
|
US9034883B2
(en)
|
2010-11-15 |
2015-05-19 |
Boehringer Ingelheim International Gmbh |
Vasoprotective and cardioprotective antidiabetic therapy
|
TR201010618A2
(en)
*
|
2010-12-20 |
2012-07-23 |
Bi̇lgi̇ç Mahmut |
An oral dosage form comprising imatinib and the manufacture of an oral dosage form
|
JP2014500308A
(en)
|
2010-12-21 |
2014-01-09 |
ノバルティス アーゲー |
Biheteroaryl compounds as VPS34 inhibitors
|
WO2012090221A1
(en)
|
2010-12-29 |
2012-07-05 |
Cadila Healthcare Limited |
Novel salts of imatinib
|
WO2012107500A1
(en)
|
2011-02-10 |
2012-08-16 |
Novartis Ag |
[1, 2, 4] triazolo [4, 3 -b] pyridazine compounds as inhibitors of the c-met tyrosine kinase
|
TWI592411B
(en)
|
2011-02-23 |
2017-07-21 |
英特爾立秦有限責任公司 |
Combination of kinase inhibitors and uses thereof
|
WO2012116237A2
(en)
|
2011-02-23 |
2012-08-30 |
Intellikine, Llc |
Heterocyclic compounds and uses thereof
|
CZ305457B6
(en)
|
2011-02-28 |
2015-09-30 |
Ústav organické chemie a biochemie, Akademie věd ČR v. v. i. |
Pyrimidine compounds inhibiting formation of nitrogen monoxide and prostaglandin E2, process for their preparation and use
|
EP2683722A1
(en)
|
2011-03-08 |
2014-01-15 |
Novartis AG |
Fluorophenyl bicyclic heteroaryl compounds
|
PL394169A1
(en)
|
2011-03-09 |
2012-09-10 |
Adamed Spółka Z Ograniczoną Odpowiedzialnością |
The pharmaceutical composition of imatinib mesylate for filling unit dosage forms and the method for its preparation
|
EP2508525A1
(en)
|
2011-04-05 |
2012-10-10 |
Bayer Pharma Aktiengesellschaft |
Substituted 2,3-dihydroimidazo[1,2-c]quinazoline salts
|
WO2012149014A1
(en)
|
2011-04-25 |
2012-11-01 |
OSI Pharmaceuticals, LLC |
Use of emt gene signatures in cancer drug discovery, diagnostics, and treatment
|
ES2656218T3
(en)
|
2011-04-28 |
2018-02-26 |
Novartis Ag |
17 alpha-hydroxylase / C17,20-lyase inhibitors
|
CN103501612B
(en)
|
2011-05-04 |
2017-03-29 |
阿里亚德医药股份有限公司 |
The compound that cell is bred in cancer caused by suppression EGF-R ELISA
|
CN102796110B
(en)
*
|
2011-05-23 |
2016-03-30 |
复旦大学 |
Aniline pyrimidine compound and its production and use
|
CA2838029A1
(en)
|
2011-06-09 |
2012-12-13 |
Novartis Ag |
Heterocyclic sulfonamide derivatives
|
WO2012175520A1
(en)
|
2011-06-20 |
2012-12-27 |
Novartis Ag |
Hydroxy substituted isoquinolinone derivatives
|
US8859586B2
(en)
|
2011-06-20 |
2014-10-14 |
Novartis Ag |
Cyclohexyl isoquinolinone compounds
|
US9750700B2
(en)
|
2011-06-22 |
2017-09-05 |
Natco Pharma Limited |
Imatinib mesylate oral pharmaceutical composition and process for preparation thereof
|
EP2723740A1
(en)
|
2011-06-27 |
2014-04-30 |
Novartis AG |
Solid forms and salts of tetrahydro-pyrido-pyrimidine derivatives
|
ITMI20111309A1
(en)
|
2011-07-14 |
2013-01-15 |
Italiana Sint Spa |
PREPARATION PROCEDURE OF IMATINIB MESILATO
|
HUE043540T2
(en)
|
2011-07-15 |
2019-08-28 |
Boehringer Ingelheim Int |
Substituted dimeric quinazoline derivative, its preparation and its use in pharmaceutical compositions for the treatment of type i and ii diabetes
|
WO2013035102A1
(en)
|
2011-09-05 |
2013-03-14 |
Natco Pharma Limited |
Processes for the preparation of imatinib base and intermediates thereof
|
EP2755976B1
(en)
|
2011-09-15 |
2018-07-18 |
Novartis AG |
6-substituted 3-(quinolin-6-ylthio)-[1,2,4]triazolo[4,3-a]pyridines as c-met tyrosine kinase inhibitors
|
US9707231B2
(en)
|
2011-11-01 |
2017-07-18 |
Modgene, Llc |
Compositions and methods for reduction of amyloid-beta load
|
RU2486180C1
(en)
*
|
2011-11-02 |
2013-06-27 |
Общество с ограниченной ответственностью "ТехноХим" (ООО "ТехноХим") |
Method for preparing 2-arylamino-4-hetarylpyrimidines
|
JP5992054B2
(en)
|
2011-11-29 |
2016-09-14 |
ノバルティス アーゲー |
Pyrazolopyrrolidine compound
|
US9408885B2
(en)
|
2011-12-01 |
2016-08-09 |
Vib Vzw |
Combinations of therapeutic agents for treating melanoma
|
CN103159739A
(en)
*
|
2011-12-09 |
2013-06-19 |
天津市国际生物医药联合研究院有限公司 |
1, 4-disubstituted-1, 2, 3-triazole compounds and preparation method thereof
|
EP2794594A1
(en)
|
2011-12-22 |
2014-10-29 |
Novartis AG |
Quinoline derivatives
|
AP4055A
(en)
|
2011-12-22 |
2017-03-07 |
Novartis Ag |
Dihydro-benzo-oxazine and dihydro-pyrido-oxazine derivatives
|
BR112014015308A2
(en)
|
2011-12-23 |
2017-06-13 |
Novartis Ag |
compounds for inhibiting bcl2 interaction with binding counterparts
|
CA2859876A1
(en)
|
2011-12-23 |
2013-06-27 |
Novartis Ag |
Compounds for inhibiting the interaction of bcl2 with binding partners
|
CA2859873A1
(en)
|
2011-12-23 |
2013-06-27 |
Novartis Ag |
Compounds for inhibiting the interaction of bcl2 with binding partners
|
US20130178520A1
(en)
|
2011-12-23 |
2013-07-11 |
Duke University |
Methods of treatment using arylcyclopropylamine compounds
|
CA2859869A1
(en)
|
2011-12-23 |
2013-06-27 |
Novartis Ag |
Compounds for inhibiting the interaction of bcl2 with binding partners
|
US9126980B2
(en)
|
2011-12-23 |
2015-09-08 |
Novartis Ag |
Compounds for inhibiting the interaction of BCL2 with binding partners
|
US20130172244A1
(en)
|
2011-12-29 |
2013-07-04 |
Thomas Klein |
Subcutaneous therapeutic use of dpp-4 inhibitor
|
PL226174B1
(en)
|
2011-12-30 |
2017-06-30 |
Inst Farm |
Combination therapy of non-small-cell lung carcinoma
|
JO3357B1
(en)
|
2012-01-26 |
2019-03-13 |
Novartis Ag |
Imidazopyrrolidinone compounds
|
WO2013120852A1
(en)
|
2012-02-13 |
2013-08-22 |
Grindeks, A Joint Stock Company |
Intermediates for a novel process of preparing imatinib and related tyrosine kinase inhibitors
|
WO2013136141A1
(en)
|
2012-03-13 |
2013-09-19 |
Fresenius Kabi Oncology Ltd. |
An improved process for the preparation of alpha form of imatinib mesylate
|
CA2868202C
(en)
|
2012-04-03 |
2021-08-10 |
Novartis Ag |
Combination products with tyrosine kinase inhibitors and their use
|
WO2013152252A1
(en)
|
2012-04-06 |
2013-10-10 |
OSI Pharmaceuticals, LLC |
Combination anti-cancer therapy
|
AU2013253541A1
(en)
|
2012-04-24 |
2014-11-20 |
Chugai Seiyaku Kabushiki Kaisha |
Quinazolinedione derivative
|
TW201348187A
(en)
|
2012-04-24 |
2013-12-01 |
Chugai Pharmaceutical Co Ltd |
Benzamide derivative
|
WO2013169401A1
(en)
|
2012-05-05 |
2013-11-14 |
Ariad Pharmaceuticals, Inc. |
Compounds for inhibiting cell proliferation in egfr-driven cancers
|
WO2013171166A1
(en)
|
2012-05-14 |
2013-11-21 |
Boehringer Ingelheim International Gmbh |
A xanthine derivative as dpp-4 inhibitor for use in the treatment of sirs and/or sepsis
|
EP3685839A1
(en)
|
2012-05-14 |
2020-07-29 |
Boehringer Ingelheim International GmbH |
Linagliptin for use in the treatment of albuminuria and kidney related diseases
|
WO2013174767A1
(en)
|
2012-05-24 |
2013-11-28 |
Boehringer Ingelheim International Gmbh |
A xanthine derivative as dpp -4 inhibitor for use in modifying food intake and regulating food preference
|
EP2854812A1
(en)
|
2012-05-24 |
2015-04-08 |
Boehringer Ingelheim International GmbH |
A xanthine derivative as dpp -4 inhibitor for use in the treatment of autoimmune diabetes, particularly lada
|
US9365576B2
(en)
|
2012-05-24 |
2016-06-14 |
Novartis Ag |
Pyrrolopyrrolidinone compounds
|
JP6427097B2
(en)
|
2012-06-15 |
2018-11-21 |
ザ ブリガム アンド ウィメンズ ホスピタル インコーポレイテッドThe Brigham and Women’s Hospital, Inc. |
Compositions for treating cancer and methods for producing said compositions
|
WO2014016848A2
(en)
|
2012-07-24 |
2014-01-30 |
Laurus Labs Private Limited |
Solid forms of tyrosine kinase inhibitors, process for the preparation and their pharmaceutical composition thereof
|
EP2879675B1
(en)
|
2012-08-06 |
2019-11-13 |
Duke University |
Compounds and methods for targeting hsp90
|
WO2014041551A1
(en)
|
2012-09-14 |
2014-03-20 |
Natco Pharma Limited |
Formulation comprising imatinib as oral solution
|
CN103664787B
(en)
|
2012-09-17 |
2015-09-09 |
南京圣和药业股份有限公司 |
Alkynes heteroaromatic ring compounds and application thereof
|
WO2014052619A1
(en)
|
2012-09-27 |
2014-04-03 |
Irm Llc |
Piperidine derivatives and compositions as modulators of gpr119 activity
|
JP2015531355A
(en)
|
2012-09-28 |
2015-11-02 |
ハンジョウ ベンシェン ファーマシューティカル シーオー., エルティーディー.Hangzhou Bensheng Pharmaceutical Co., Ltd. |
Pharmaceutical composition for tumor treatment and application thereof
|
AU2013326850B2
(en)
*
|
2012-10-04 |
2017-09-21 |
Inhibikase Therapeutics, Inc. |
Novel compounds, their preparation and their uses
|
CN105377288B
(en)
|
2012-11-05 |
2019-11-15 |
达纳-法伯癌症研究所股份有限公司 |
The composition of XBP1, CD138 and CS1 peptide prepares the purposes of drug
|
TW201422625A
(en)
|
2012-11-26 |
2014-06-16 |
Novartis Ag |
Solid form of dihydro-pyrido-oxazine derivative
|
CN103848812B
(en)
*
|
2012-12-04 |
2016-08-03 |
北大方正集团有限公司 |
The method of refined imatinib
|
CN103044394A
(en)
*
|
2012-12-20 |
2013-04-17 |
北京理工大学 |
Phenyl aminopyrimidine derivant and preparation method and application thereof
|
EP2749271A1
(en)
|
2012-12-31 |
2014-07-02 |
Deva Holding Anonim Sirketi |
Optimized manufacturing method and pharmaceutical formulation of imatinib
|
WO2014115077A1
(en)
|
2013-01-22 |
2014-07-31 |
Novartis Ag |
Substituted purinone compounds
|
EP2948453B1
(en)
|
2013-01-22 |
2017-08-02 |
Novartis AG |
Pyrazolo[3,4-d]pyrimidinone compounds as inhibitors of the p53/mdm2 interaction
|
WO2014124860A1
(en)
|
2013-02-14 |
2014-08-21 |
Boehringer Ingelheim International Gmbh |
Specific pde4b-inhibitors for the treatment of diabetes mellitus
|
WO2014128612A1
(en)
|
2013-02-20 |
2014-08-28 |
Novartis Ag |
Quinazolin-4-one derivatives
|
PT2958943T
(en)
|
2013-02-20 |
2019-12-17 |
Novartis Ag |
Treatment of cancer using humanized anti-egfrviii chimeric antigen receptor
|
CA2906542A1
(en)
|
2013-03-15 |
2014-09-25 |
Intellikine, Llc |
Combination of kinase inhibitors and uses thereof
|
WO2014155268A2
(en)
|
2013-03-25 |
2014-10-02 |
Novartis Ag |
Fgf-r tyrosine kinase activity inhibitors - use in diseases associated with lack of or reduced snf5 activity
|
US9611283B1
(en)
|
2013-04-10 |
2017-04-04 |
Ariad Pharmaceuticals, Inc. |
Methods for inhibiting cell proliferation in ALK-driven cancers
|
EP2803353B1
(en)
|
2013-05-14 |
2018-05-23 |
Hetero Research Foundation |
Compositions of Imatinib
|
US20150018376A1
(en)
|
2013-05-17 |
2015-01-15 |
Novartis Ag |
Pyrimidin-4-yl)oxy)-1h-indole-1-carboxamide derivatives and use thereof
|
UY35675A
(en)
|
2013-07-24 |
2015-02-27 |
Novartis Ag |
SUBSTITUTED DERIVATIVES OF QUINAZOLIN-4-ONA
|
WO2015022663A1
(en)
|
2013-08-14 |
2015-02-19 |
Novartis Ag |
Compounds and compositions as inhibitors of mek
|
WO2015022664A1
(en)
|
2013-08-14 |
2015-02-19 |
Novartis Ag |
Compounds and compositions as inhibitors of mek
|
US9227969B2
(en)
|
2013-08-14 |
2016-01-05 |
Novartis Ag |
Compounds and compositions as inhibitors of MEK
|
WO2015042078A2
(en)
|
2013-09-22 |
2015-03-26 |
Calitor Sciences, Llc |
Substituted aminopyrimidine compounds and methods of use
|
US9901579B2
(en)
|
2013-10-17 |
2018-02-27 |
Sartar Therapeutics Ltd |
Compositions comprising phosphodiesterase inhibitors for use in the treatment of a solid tumor in a human patient
|
CN105829285A
(en)
|
2013-10-23 |
2016-08-03 |
中外制药株式会社 |
Quinazolinone and isoquinolinone derivative
|
TW201605450A
(en)
|
2013-12-03 |
2016-02-16 |
諾華公司 |
Combination of Mdm2 inhibitor and BRAF inhibitor and their use
|
WO2015148714A1
(en)
|
2014-03-25 |
2015-10-01 |
Duke University |
Heat shock protein 70 (hsp-70) receptor ligands
|
WO2015145388A2
(en)
|
2014-03-27 |
2015-10-01 |
Novartis Ag |
Methods of treating colorectal cancers harboring upstream wnt pathway mutations
|
US9399637B2
(en)
|
2014-03-28 |
2016-07-26 |
Calitor Sciences, Llc |
Substituted heteroaryl compounds and methods of use
|
AU2015241198A1
(en)
|
2014-04-03 |
2016-11-17 |
Invictus Oncology Pvt. Ltd. |
Supramolecular combinatorial therapeutics
|
EP2927223B1
(en)
|
2014-04-04 |
2016-06-29 |
F.I.S.- Fabbrica Italiana Sintetici S.p.A. |
Process for preparing imatinib and salts thereof, free of genotoxic impurity f
|
WO2015156674A2
(en)
|
2014-04-10 |
2015-10-15 |
Stichting Het Nederlands Kanker Instituut |
Method for treating cancer
|
WO2016011658A1
(en)
|
2014-07-25 |
2016-01-28 |
Novartis Ag |
Combination therapy
|
CA2954862A1
(en)
|
2014-07-31 |
2016-02-04 |
Novartis Ag |
Combination therapy
|
WO2016059220A1
(en)
|
2014-10-16 |
2016-04-21 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Tcr-activating agents for use in the treatment of t-all
|
CN105585556A
(en)
*
|
2014-11-13 |
2016-05-18 |
连云港杰瑞药业有限公司 |
Synthetic method of imatinib
|
WO2017044434A1
(en)
|
2015-09-11 |
2017-03-16 |
Sunshine Lake Pharma Co., Ltd. |
Substituted heteroaryl compounds and methods of use
|
EA035891B1
(en)
|
2016-01-25 |
2020-08-27 |
КРКА, д.д., НОВО МЕСТО |
Fast dispersible pharmaceutical composition comprising tyrosine-kinase inhibitor
|
EA038531B1
(en)
|
2016-03-25 |
2021-09-10 |
Аб Сьянс |
Method for treatment of an amyotrophic lateral sclerosis, use of a pharmaceutical composition comprising masitinib
|
WO2017184956A1
(en)
|
2016-04-22 |
2017-10-26 |
Duke University |
Compounds and methods for targeting hsp90
|
BR112018072401A2
(en)
|
2016-06-10 |
2019-02-19 |
Boehringer Ingelheim International Gmbh |
combinations of linagliptin and metformin
|
EP3257499A1
(en)
|
2016-06-17 |
2017-12-20 |
Vipharm S.A. |
Process for preparation of imatinib methanesulfonate capsules
|
CN107652269A
(en)
*
|
2016-07-26 |
2018-02-02 |
江苏豪森药业集团有限公司 |
Methanesulfonic acid fluorine imatinib purification of intermediate method
|
WO2018039203A1
(en)
|
2016-08-23 |
2018-03-01 |
Oncopep, Inc. |
Peptide vaccines and durvalumab for treating multiple myeloma
|
US20190209669A1
(en)
|
2016-08-23 |
2019-07-11 |
Oncopep, Inc. |
Peptide vaccines and durvalumab for treating breast cancer
|
CN107805240A
(en)
*
|
2016-09-08 |
2018-03-16 |
中国科学院合肥物质科学研究院 |
A kind of new PDGFR kinase inhibitors and application thereof
|
JP2019536471A
(en)
|
2016-09-27 |
2019-12-19 |
セロ・セラピューティクス・インコーポレイテッドCERO Therapeutics, Inc. |
Chimeric engulfment receptor molecule
|
US10927083B2
(en)
|
2016-09-29 |
2021-02-23 |
Duke University |
Substituted benzimidazoles as inhibitors of transforming growth factor-β kinase
|
US10207998B2
(en)
|
2016-09-29 |
2019-02-19 |
Duke University |
Substituted benzimidazole and substituted benzothiazole inhibitors of transforming growth factor-β kinase and methods of use thereof
|
EP3333162A1
(en)
|
2016-12-12 |
2018-06-13 |
Silesian Catalysts sp. z o.o. |
Metod for preparing n-(2-methyl-5-nitrophenyl)-4-(pyridin-3-yl)pyrimidin-2-amine
|
CN107089969B
(en)
*
|
2017-04-26 |
2020-04-24 |
黑龙江鑫创生物科技开发有限公司 |
Method for synthesizing imatinib intermediate
|
CA3073421A1
(en)
|
2017-09-26 |
2019-04-04 |
Daniel Mark COREY |
Chimeric engulfment receptor molecules and methods of use
|
WO2019083960A1
(en)
|
2017-10-24 |
2019-05-02 |
Oncopep, Inc. |
Peptide vaccines and hdac inhibitors for treating multiple myeloma
|
US20200276304A1
(en)
|
2017-10-24 |
2020-09-03 |
Oncopep, Inc. |
Peptide vaccines and pembrolizumab for treating breast cancer
|
EP3710006A4
(en)
|
2017-11-19 |
2021-09-01 |
Sunshine Lake Pharma Co., Ltd. |
Substituted heteroaryl compounds and methods of use
|
JP7021356B2
(en)
|
2017-12-21 |
2022-02-16 |
ヘフェイ インスティテューツ オブ フィジカル サイエンス, チャイニーズ アカデミー オブ サイエンシーズ |
Pyrimidine derivative kinase inhibitors
|
KR20200112900A
(en)
|
2018-01-20 |
2020-10-05 |
선샤인 레이크 파르마 컴퍼니 리미티드 |
Substituted aminopyrimidine compounds and methods of use thereof
|
RU2020135107A
(en)
|
2018-03-28 |
2022-04-29 |
Серо Терапьютикс, Инк. |
CELLULAR IMMUNOTHERAPEUTIC COMPOSITIONS AND THEIR APPLICATIONS
|
US20210087251A1
(en)
|
2018-03-28 |
2021-03-25 |
Cero Therapeutics, Inc. |
Chimeric tim4 receptors and uses thereof
|
US20210024607A1
(en)
|
2018-03-28 |
2021-01-28 |
Cero Therapeutics, Inc. |
Expression vectors for chimeric engulfment receptors, genetically modified host cells, and uses thereof
|
US20210299129A1
(en)
|
2018-07-17 |
2021-09-30 |
Boehringer Ingelheim International Gmbh |
Cardiosafe Antidiabetic Therapy
|
MX2021000554A
(en)
|
2018-07-17 |
2021-03-29 |
Boehringer Ingelheim Int |
Cardio- and renosafe antidiabetic therapy.
|
WO2020023628A1
(en)
|
2018-07-24 |
2020-01-30 |
Hygia Pharmaceuticals, Llc |
Compounds, derivatives, and analogs for cancer
|
US20220265653A1
(en)
|
2019-07-15 |
2022-08-25 |
Intas Pharmaceuticals Ltd. |
Pharmaceutical composition of imatinib
|
EP4038097A1
(en)
|
2019-10-03 |
2022-08-10 |
Cero Therapeutics, Inc. |
Chimeric tim4 receptors and uses thereof
|
US20220395553A1
(en)
|
2019-11-14 |
2022-12-15 |
Cohbar, Inc. |
Cxcr4 antagonist peptides
|
WO2021233534A1
(en)
|
2020-05-20 |
2021-11-25 |
Pvac Medical Technologies Ltd |
Use of substance and pharmaceutical composition thereof, and medical treatments or uses thereof
|
WO2021185844A1
(en)
|
2020-03-16 |
2021-09-23 |
Pvac Medical Technologies Ltd |
Use of substance and pharmaceutical composition thereof, and medical treatments or uses thereof
|
WO2021228983A1
(en)
|
2020-05-13 |
2021-11-18 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
A pharmaceutical composition comprising an arsenic compound, an inductor of type-1 ifn and a protein kinase inhibitor for treating cancer
|
EP4192509A1
(en)
|
2020-08-05 |
2023-06-14 |
Ellipses Pharma Ltd |
Treatment of cancer using a cyclodextrin-containing polymer-topoisomerase inhibitor conjugate and a parp inhibitor
|
WO2022036285A1
(en)
|
2020-08-14 |
2022-02-17 |
Cero Therapeutics, Inc. |
Compositions and methods for treating cancer with chimeric tim receptors in combination with inhibitors of poly (adp-ribose) polymerase
|
WO2022036265A1
(en)
|
2020-08-14 |
2022-02-17 |
Cero Therapeutics, Inc. |
Chimeric tim receptors and uses thereof
|
WO2022036287A1
(en)
|
2020-08-14 |
2022-02-17 |
Cero Therapeutics, Inc. |
Anti-cd72 chimeric receptors and uses thereof
|
TW202237638A
(en)
|
2020-12-09 |
2022-10-01 |
日商武田藥品工業股份有限公司 |
Compositions of guanylyl cyclase c (gcc) antigen binding agents and methods of use thereof
|
CN117203223A
(en)
|
2021-02-26 |
2023-12-08 |
凯洛尼亚疗法有限公司 |
Lymphocyte targeting lentiviral vectors
|
WO2023010097A1
(en)
|
2021-07-28 |
2023-02-02 |
Cero Therapeutics, Inc. |
Chimeric tim4 receptors and uses thereof
|
WO2024030441A1
(en)
|
2022-08-02 |
2024-02-08 |
National University Corporation Hokkaido University |
Methods of improving cellular therapy with organelle complexes
|