CN1357038A - 乳酸细菌的组合及其用于预防和/或治疗感染和炎症的用途 - Google Patents
乳酸细菌的组合及其用于预防和/或治疗感染和炎症的用途 Download PDFInfo
- Publication number
- CN1357038A CN1357038A CN00809309A CN00809309A CN1357038A CN 1357038 A CN1357038 A CN 1357038A CN 00809309 A CN00809309 A CN 00809309A CN 00809309 A CN00809309 A CN 00809309A CN 1357038 A CN1357038 A CN 1357038A
- Authority
- CN
- China
- Prior art keywords
- lactobacillus
- bacterium
- combination
- composition
- lactic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 241000894006 Bacteria Species 0.000 title claims abstract description 32
- 238000011282 treatment Methods 0.000 title claims abstract description 6
- 208000015181 infectious disease Diseases 0.000 title claims abstract description 5
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 title abstract description 10
- 239000004310 lactic acid Substances 0.000 title abstract description 5
- 235000014655 lactic acid Nutrition 0.000 title abstract description 5
- 230000004968 inflammatory condition Effects 0.000 title abstract 2
- 230000002265 prevention Effects 0.000 title abstract 2
- 210000000214 mouth Anatomy 0.000 claims abstract description 13
- 239000000047 product Substances 0.000 claims abstract description 6
- 210000001215 vagina Anatomy 0.000 claims abstract description 5
- 241000700605 Viruses Species 0.000 claims abstract description 4
- 235000015872 dietary supplement Nutrition 0.000 claims abstract description 4
- 210000001331 nose Anatomy 0.000 claims abstract description 4
- 239000000825 pharmaceutical preparation Substances 0.000 claims abstract description 4
- 210000003708 urethra Anatomy 0.000 claims abstract description 4
- 239000000203 mixture Substances 0.000 claims description 37
- 230000001580 bacterial effect Effects 0.000 claims description 26
- 241000186660 Lactobacillus Species 0.000 claims description 21
- 229940039696 lactobacillus Drugs 0.000 claims description 21
- 241000186869 Lactobacillus salivarius Species 0.000 claims description 18
- 241000186840 Lactobacillus fermentum Species 0.000 claims description 15
- 241000218492 Lactobacillus crispatus Species 0.000 claims description 14
- 229940012969 lactobacillus fermentum Drugs 0.000 claims description 12
- 206010061218 Inflammation Diseases 0.000 claims description 9
- 239000003795 chemical substances by application Substances 0.000 claims description 9
- 230000004054 inflammatory process Effects 0.000 claims description 9
- 241000186000 Bifidobacterium Species 0.000 claims description 8
- 241000193830 Bacillus <bacterium> Species 0.000 claims description 7
- 239000002674 ointment Substances 0.000 claims description 7
- 239000003826 tablet Substances 0.000 claims description 7
- 241000186606 Lactobacillus gasseri Species 0.000 claims description 6
- 239000000843 powder Substances 0.000 claims description 6
- 208000011580 syndromic disease Diseases 0.000 claims description 6
- 229940034610 toothpaste Drugs 0.000 claims description 6
- 239000000606 toothpaste Substances 0.000 claims description 6
- 230000002882 anti-plaque Effects 0.000 claims description 5
- 239000000499 gel Substances 0.000 claims description 5
- 239000006189 buccal tablet Substances 0.000 claims description 4
- 229940112822 chewing gum Drugs 0.000 claims description 4
- 235000015218 chewing gum Nutrition 0.000 claims description 4
- 229940120293 vaginal suppository Drugs 0.000 claims description 4
- 239000006216 vaginal suppository Substances 0.000 claims description 4
- 241000186018 Bifidobacterium adolescentis Species 0.000 claims description 3
- 241000186012 Bifidobacterium breve Species 0.000 claims description 3
- 241000186011 Bifidobacterium catenulatum Species 0.000 claims description 3
- 241000186020 Bifidobacterium dentium Species 0.000 claims description 3
- 241001430190 Eggerthia catenaformis Species 0.000 claims description 3
- 241000792859 Enema Species 0.000 claims description 3
- 239000001828 Gelatine Substances 0.000 claims description 3
- 241001134659 Lactobacillus curvatus Species 0.000 claims description 3
- 241001561398 Lactobacillus jensenii Species 0.000 claims description 3
- 241001134654 Lactobacillus leichmannii Species 0.000 claims description 3
- 241000194017 Streptococcus Species 0.000 claims description 3
- 206010046914 Vaginal infection Diseases 0.000 claims description 3
- 201000008100 Vaginitis Diseases 0.000 claims description 3
- 229940046011 buccal tablet Drugs 0.000 claims description 3
- 239000002775 capsule Substances 0.000 claims description 3
- 235000009508 confectionery Nutrition 0.000 claims description 3
- 229940095399 enema Drugs 0.000 claims description 3
- 239000007920 enema Substances 0.000 claims description 3
- 229920000159 gelatin Polymers 0.000 claims description 3
- 235000019322 gelatine Nutrition 0.000 claims description 3
- 201000011486 lichen planus Diseases 0.000 claims description 3
- 244000005700 microbiome Species 0.000 claims description 3
- 229940023488 pill Drugs 0.000 claims description 3
- 239000006187 pill Substances 0.000 claims description 3
- 239000007921 spray Substances 0.000 claims description 3
- 239000000829 suppository Substances 0.000 claims description 3
- 239000000725 suspension Substances 0.000 claims description 3
- 206010010741 Conjunctivitis Diseases 0.000 claims description 2
- 208000005232 Glossitis Diseases 0.000 claims description 2
- 206010028116 Mucosal inflammation Diseases 0.000 claims description 2
- 201000010927 Mucositis Diseases 0.000 claims description 2
- 208000005141 Otitis Diseases 0.000 claims description 2
- 241000721454 Pemphigus Species 0.000 claims description 2
- 206010036774 Proctitis Diseases 0.000 claims description 2
- 208000008117 Salivary Gland Calculi Diseases 0.000 claims description 2
- 206010039796 Seborrhoeic keratosis Diseases 0.000 claims description 2
- 206010040628 Sialoadenitis Diseases 0.000 claims description 2
- 239000003963 antioxidant agent Substances 0.000 claims description 2
- 230000003078 antioxidant effect Effects 0.000 claims description 2
- 208000002399 aphthous stomatitis Diseases 0.000 claims description 2
- 208000002352 blister Diseases 0.000 claims description 2
- 239000003814 drug Substances 0.000 claims description 2
- 208000019258 ear infection Diseases 0.000 claims description 2
- 239000004744 fabric Substances 0.000 claims description 2
- 229910017053 inorganic salt Inorganic materials 0.000 claims description 2
- 239000002324 mouth wash Substances 0.000 claims description 2
- 201000001245 periodontitis Diseases 0.000 claims description 2
- 238000004321 preservation Methods 0.000 claims description 2
- 201000007094 prostatitis Diseases 0.000 claims description 2
- 206010039083 rhinitis Diseases 0.000 claims description 2
- 201000003385 seborrheic keratosis Diseases 0.000 claims description 2
- 208000001050 sialadenitis Diseases 0.000 claims description 2
- 201000009789 sialolithiasis Diseases 0.000 claims description 2
- 201000009890 sinusitis Diseases 0.000 claims description 2
- 208000003265 stomatitis Diseases 0.000 claims description 2
- 208000000143 urethritis Diseases 0.000 claims description 2
- 239000011782 vitamin Substances 0.000 claims description 2
- 229940088594 vitamin Drugs 0.000 claims description 2
- 229930003231 vitamin Natural products 0.000 claims description 2
- 235000013343 vitamin Nutrition 0.000 claims description 2
- 150000003722 vitamin derivatives Chemical class 0.000 claims description 2
- 206010019375 Helicobacter infections Diseases 0.000 claims 1
- 239000003513 alkali Substances 0.000 claims 1
- 125000003277 amino group Chemical group 0.000 claims 1
- 239000002260 anti-inflammatory agent Substances 0.000 claims 1
- 229940121363 anti-inflammatory agent Drugs 0.000 claims 1
- 239000004075 cariostatic agent Substances 0.000 claims 1
- 238000004113 cell culture Methods 0.000 claims 1
- 229940051866 mouthwash Drugs 0.000 claims 1
- 241000233866 Fungi Species 0.000 abstract 1
- 210000005069 ears Anatomy 0.000 abstract 1
- 210000001508 eye Anatomy 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 10
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 8
- 240000001929 Lactobacillus brevis Species 0.000 description 8
- 239000004475 Arginine Substances 0.000 description 6
- 235000013957 Lactobacillus brevis Nutrition 0.000 description 6
- ODKSFYDXXFIFQN-UHFFFAOYSA-N arginine Natural products OC(=O)C(N)CCCNC(N)=N ODKSFYDXXFIFQN-UHFFFAOYSA-N 0.000 description 6
- 208000002064 Dental Plaque Diseases 0.000 description 4
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 4
- DBMJMQXJHONAFJ-UHFFFAOYSA-M Sodium laurylsulphate Chemical compound [Na+].CCCCCCCCCCCCOS([O-])(=O)=O DBMJMQXJHONAFJ-UHFFFAOYSA-M 0.000 description 4
- 230000000694 effects Effects 0.000 description 4
- 235000011187 glycerol Nutrition 0.000 description 4
- HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 description 4
- 239000001683 mentha spicata herb oil Substances 0.000 description 4
- 238000002360 preparation method Methods 0.000 description 4
- 235000019333 sodium laurylsulphate Nutrition 0.000 description 4
- 235000019721 spearmint oil Nutrition 0.000 description 4
- 239000004278 EU approved seasoning Substances 0.000 description 3
- -1 Polyethylene Polymers 0.000 description 3
- 239000004141 Sodium laurylsulphate Substances 0.000 description 3
- 235000011194 food seasoning agent Nutrition 0.000 description 3
- 125000001475 halogen functional group Chemical group 0.000 description 3
- 230000002401 inhibitory effect Effects 0.000 description 3
- 239000000463 material Substances 0.000 description 3
- CVHZOJJKTDOEJC-UHFFFAOYSA-N saccharin Chemical compound C1=CC=C2C(=O)NS(=O)(=O)C2=C1 CVHZOJJKTDOEJC-UHFFFAOYSA-N 0.000 description 3
- 239000000243 solution Substances 0.000 description 3
- 241000196324 Embryophyta Species 0.000 description 2
- 241000207201 Gardnerella vaginalis Species 0.000 description 2
- 244000199866 Lactobacillus casei Species 0.000 description 2
- 235000013958 Lactobacillus casei Nutrition 0.000 description 2
- 240000006024 Lactobacillus plantarum Species 0.000 description 2
- UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 description 2
- 241000194019 Streptococcus mutans Species 0.000 description 2
- 241000194020 Streptococcus thermophilus Species 0.000 description 2
- 208000025865 Ulcer Diseases 0.000 description 2
- 239000002253 acid Substances 0.000 description 2
- 239000007864 aqueous solution Substances 0.000 description 2
- XAAHAAMILDNBPS-UHFFFAOYSA-L calcium hydrogenphosphate dihydrate Chemical compound O.O.[Ca+2].OP([O-])([O-])=O XAAHAAMILDNBPS-UHFFFAOYSA-L 0.000 description 2
- 238000006243 chemical reaction Methods 0.000 description 2
- 230000003203 everyday effect Effects 0.000 description 2
- 239000000706 filtrate Substances 0.000 description 2
- 210000004283 incisor Anatomy 0.000 description 2
- 238000007689 inspection Methods 0.000 description 2
- 229940017800 lactobacillus casei Drugs 0.000 description 2
- 235000019359 magnesium stearate Nutrition 0.000 description 2
- 230000003211 malignant effect Effects 0.000 description 2
- 210000004400 mucous membrane Anatomy 0.000 description 2
- 230000001717 pathogenic effect Effects 0.000 description 2
- 230000000452 restraining effect Effects 0.000 description 2
- 239000000377 silicon dioxide Substances 0.000 description 2
- 231100000397 ulcer Toxicity 0.000 description 2
- 229940044977 vaginal tablet Drugs 0.000 description 2
- 239000000003 vaginal tablet Substances 0.000 description 2
- 241000193815 Atopobium minutum Species 0.000 description 1
- 241000186014 Bifidobacterium angulatum Species 0.000 description 1
- 241000186016 Bifidobacterium bifidum Species 0.000 description 1
- 241001608472 Bifidobacterium longum Species 0.000 description 1
- 241000186015 Bifidobacterium longum subsp. infantis Species 0.000 description 1
- 241000149420 Bothrometopus brevis Species 0.000 description 1
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 description 1
- 241000588724 Escherichia coli Species 0.000 description 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- 206010018612 Gonorrhoea Diseases 0.000 description 1
- 241000589989 Helicobacter Species 0.000 description 1
- 241000590002 Helicobacter pylori Species 0.000 description 1
- 240000001046 Lactobacillus acidophilus Species 0.000 description 1
- 235000013956 Lactobacillus acidophilus Nutrition 0.000 description 1
- 241000186679 Lactobacillus buchneri Species 0.000 description 1
- 241000186673 Lactobacillus delbrueckii Species 0.000 description 1
- 235000013965 Lactobacillus plantarum Nutrition 0.000 description 1
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 description 1
- 229930195725 Mannitol Natural products 0.000 description 1
- 244000246386 Mentha pulegium Species 0.000 description 1
- 235000016257 Mentha pulegium Nutrition 0.000 description 1
- 235000004357 Mentha x piperita Nutrition 0.000 description 1
- 102000003992 Peroxidases Human genes 0.000 description 1
- 239000004698 Polyethylene Substances 0.000 description 1
- 241000607142 Salmonella Species 0.000 description 1
- 208000021386 Sjogren Syndrome Diseases 0.000 description 1
- 235000021355 Stearic acid Nutrition 0.000 description 1
- TVXBFESIOXBWNM-UHFFFAOYSA-N Xylitol Natural products OCCC(O)C(O)C(O)CCO TVXBFESIOXBWNM-UHFFFAOYSA-N 0.000 description 1
- 239000013543 active substance Substances 0.000 description 1
- 239000000908 ammonium hydroxide Substances 0.000 description 1
- 230000008485 antagonism Effects 0.000 description 1
- 230000003110 anti-inflammatory effect Effects 0.000 description 1
- 239000002246 antineoplastic agent Substances 0.000 description 1
- 244000052616 bacterial pathogen Species 0.000 description 1
- HFACYLZERDEVSX-UHFFFAOYSA-N benzidine Chemical group C1=CC(N)=CC=C1C1=CC=C(N)C=C1 HFACYLZERDEVSX-UHFFFAOYSA-N 0.000 description 1
- 229940002008 bifidobacterium bifidum Drugs 0.000 description 1
- 229940004120 bifidobacterium infantis Drugs 0.000 description 1
- 229940009291 bifidobacterium longum Drugs 0.000 description 1
- 230000000740 bleeding effect Effects 0.000 description 1
- 210000001124 body fluid Anatomy 0.000 description 1
- 239000010839 body fluid Substances 0.000 description 1
- 239000001506 calcium phosphate Substances 0.000 description 1
- 229910000389 calcium phosphate Inorganic materials 0.000 description 1
- 235000011010 calcium phosphates Nutrition 0.000 description 1
- 239000000084 colloidal system Substances 0.000 description 1
- 210000001072 colon Anatomy 0.000 description 1
- 229940127089 cytotoxic agent Drugs 0.000 description 1
- 208000002925 dental caries Diseases 0.000 description 1
- 229940095079 dicalcium phosphate anhydrous Drugs 0.000 description 1
- FPAFDBFIGPHWGO-UHFFFAOYSA-N dioxosilane;oxomagnesium;hydrate Chemical compound O.[Mg]=O.[Mg]=O.[Mg]=O.O=[Si]=O.O=[Si]=O.O=[Si]=O.O=[Si]=O FPAFDBFIGPHWGO-UHFFFAOYSA-N 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 239000012153 distilled water Substances 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 238000000855 fermentation Methods 0.000 description 1
- 230000004151 fermentation Effects 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 239000003205 fragrance Substances 0.000 description 1
- 238000004108 freeze drying Methods 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- 229940037467 helicobacter pylori Drugs 0.000 description 1
- 235000001050 hortel pimenta Nutrition 0.000 description 1
- 230000036571 hydration Effects 0.000 description 1
- 238000006703 hydration reaction Methods 0.000 description 1
- 238000011534 incubation Methods 0.000 description 1
- 229940039695 lactobacillus acidophilus Drugs 0.000 description 1
- 229940072205 lactobacillus plantarum Drugs 0.000 description 1
- 239000008101 lactose Substances 0.000 description 1
- 239000000594 mannitol Substances 0.000 description 1
- 235000010355 mannitol Nutrition 0.000 description 1
- 235000012054 meals Nutrition 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- HEBKCHPVOIAQTA-UHFFFAOYSA-N meso ribitol Natural products OCC(O)C(O)C(O)CO HEBKCHPVOIAQTA-UHFFFAOYSA-N 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 239000008368 mint flavor Substances 0.000 description 1
- 239000004570 mortar (masonry) Substances 0.000 description 1
- 230000007935 neutral effect Effects 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 230000035764 nutrition Effects 0.000 description 1
- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 description 1
- OQCDKBAXFALNLD-UHFFFAOYSA-N octadecanoic acid Natural products CCCCCCCC(C)CCCCCCCCC(O)=O OQCDKBAXFALNLD-UHFFFAOYSA-N 0.000 description 1
- 108040007629 peroxidase activity proteins Proteins 0.000 description 1
- 229920000573 polyethylene Polymers 0.000 description 1
- 229920000642 polymer Polymers 0.000 description 1
- 102000004196 processed proteins & peptides Human genes 0.000 description 1
- 108090000765 processed proteins & peptides Proteins 0.000 description 1
- 125000001453 quaternary ammonium group Chemical group 0.000 description 1
- 210000003296 saliva Anatomy 0.000 description 1
- 238000012216 screening Methods 0.000 description 1
- 239000006152 selective media Substances 0.000 description 1
- 235000012239 silicon dioxide Nutrition 0.000 description 1
- 229960001866 silicon dioxide Drugs 0.000 description 1
- 229910000030 sodium bicarbonate Inorganic materials 0.000 description 1
- 235000017557 sodium bicarbonate Nutrition 0.000 description 1
- 241000894007 species Species 0.000 description 1
- 230000002269 spontaneous effect Effects 0.000 description 1
- 239000008117 stearic acid Substances 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 239000013589 supplement Substances 0.000 description 1
- 239000000375 suspending agent Substances 0.000 description 1
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
- 238000005550 wet granulation Methods 0.000 description 1
- 239000000811 xylitol Substances 0.000 description 1
- 235000010447 xylitol Nutrition 0.000 description 1
- HEBKCHPVOIAQTA-SCDXWVJYSA-N xylitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)CO HEBKCHPVOIAQTA-SCDXWVJYSA-N 0.000 description 1
- 229960002675 xylitol Drugs 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q15/00—Anti-perspirants or body deodorants
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
- A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
- A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
- A61K35/745—Bifidobacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
- A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
- A61K35/747—Lactobacilli, e.g. L. acidophilus or L. brevis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/99—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from microorganisms other than algae or fungi, e.g. protozoa or bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/04—Drugs for disorders of the respiratory system for throat disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/853—Lactobacillus
- Y10S435/855—Lactobacillus brevis
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/853—Lactobacillus
- Y10S435/856—Lactobacillus casei
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Oncology (AREA)
- Biotechnology (AREA)
- Communicable Diseases (AREA)
- Virology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pulmonology (AREA)
- Dermatology (AREA)
- Reproductive Health (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Urology & Nephrology (AREA)
- Endocrinology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Otolaryngology (AREA)
- Genetics & Genomics (AREA)
- Birds (AREA)
- Rheumatology (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Ophthalmology & Optometry (AREA)
- Gynecology & Obstetrics (AREA)
Abstract
Description
组合AB唾液乳杆菌+短乳杆菌,比例1∶1 | 4000百万 |
甘露醇 | 400 mg |
糖精 | 5 mg |
聚乙烯 | 50 mg |
硬脂酸镁 | 15 mg |
滑石粉 | 25 mg |
二氧化硅 | 5 mg |
Claims (15)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT1999RM000400A IT1306716B1 (it) | 1999-06-21 | 1999-06-21 | Associazione di batteri lattici e suo uso per la prevenzione e/o iltrattamento terapeutico di infezioni e di stati infiammatori. |
ITRM99A000400 | 1999-06-21 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN1357038A true CN1357038A (zh) | 2002-07-03 |
CN1227354C CN1227354C (zh) | 2005-11-16 |
Family
ID=11406844
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CNB008093091A Expired - Fee Related CN1227354C (zh) | 1999-06-21 | 2000-06-16 | 乳酸细菌的组合及其用于预防和/或治疗感染和炎症的用途 |
Country Status (35)
Country | Link |
---|---|
US (1) | US7052688B2 (zh) |
EP (1) | EP1194525B1 (zh) |
JP (3) | JP4949580B2 (zh) |
KR (1) | KR100712286B1 (zh) |
CN (1) | CN1227354C (zh) |
AR (2) | AR024579A1 (zh) |
AT (1) | ATE325614T1 (zh) |
AU (1) | AU775452B2 (zh) |
BR (2) | BRPI0017622B1 (zh) |
CA (1) | CA2373375C (zh) |
CZ (1) | CZ298682B6 (zh) |
DE (1) | DE60027894T2 (zh) |
DK (1) | DK1194525T3 (zh) |
DZ (1) | DZ3167A1 (zh) |
EA (1) | EA006037B1 (zh) |
EE (1) | EE04620B1 (zh) |
ES (1) | ES2262522T3 (zh) |
HK (1) | HK1047132B (zh) |
HU (1) | HUP0202051A3 (zh) |
IL (2) | IL146889A0 (zh) |
IN (1) | IN2001KO01233A (zh) |
IS (1) | IS6177A (zh) |
IT (1) | IT1306716B1 (zh) |
MA (1) | MA25775A1 (zh) |
MX (1) | MX236443B (zh) |
NO (1) | NO329324B1 (zh) |
NZ (1) | NZ516022A (zh) |
PL (1) | PL352805A1 (zh) |
PT (1) | PT1194525E (zh) |
SI (1) | SI1194525T1 (zh) |
SK (1) | SK17172001A3 (zh) |
TR (1) | TR200103606T2 (zh) |
UA (1) | UA76696C2 (zh) |
WO (1) | WO2000078322A2 (zh) |
ZA (1) | ZA200200461B (zh) |
Cited By (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN100556414C (zh) * | 2005-10-14 | 2009-11-04 | 德阳创新生物工程有限公司 | 一种具免疫调节功能的多菌组合物及其制备方法与用途 |
CN101043856B (zh) * | 2004-12-23 | 2010-05-12 | 艾蒂尔药物有限公司 | 用于鉴定和治疗阴道疾病的装置和方法 |
CN1860219B (zh) * | 2003-01-29 | 2011-07-20 | 生命大地女神有限公司 | 乳酸杆菌在减少龋齿和细菌引发龋齿中的用途 |
CN102389390A (zh) * | 2003-08-11 | 2012-03-28 | 奥洁克公司 | 维持口腔健康的组合物及方法 |
CN102690768A (zh) * | 2012-05-31 | 2012-09-26 | 江南大学 | 一株短乳杆菌及其应用 |
CN102727531A (zh) * | 2012-07-23 | 2012-10-17 | 郑州金森生物科技工程有限公司 | 一种对阴道炎具有治疗和预防作用的活性乳酸菌胶囊 |
CN103409334A (zh) * | 2013-01-16 | 2013-11-27 | 生合生物科技股份有限公司 | 抑制阴道炎病原菌之乳酸杆菌及其用途 |
CN103798392A (zh) * | 2014-03-07 | 2014-05-21 | 内蒙古伊利实业集团股份有限公司 | 具有缓解咽喉部炎症功效的益生菌食品组合物及食品 |
CN104023732A (zh) * | 2011-08-05 | 2014-09-03 | 株式会社养乐多本社 | 口腔疾患的预防或治疗剂 |
CN104232537A (zh) * | 2014-09-03 | 2014-12-24 | 中国科学院微生物研究所 | 一株弯曲乳杆菌及其应用 |
CN104277998A (zh) * | 2008-06-11 | 2015-01-14 | 巴斯夫欧洲公司 | 用于预防和/或治疗口腔恶臭的用途和方法 |
CN104293718A (zh) * | 2014-10-11 | 2015-01-21 | 中国科学院微生物研究所 | 一株詹氏乳杆菌及其应用 |
CN104622914A (zh) * | 2015-01-06 | 2015-05-20 | 占美华 | 阴道益生菌栓 |
CN104769100A (zh) * | 2012-10-25 | 2015-07-08 | 热尔韦·达诺尼公司 | 用于治疗幽门螺杆菌感染的嗜热链球菌菌株 |
CN105263504A (zh) * | 2013-05-14 | 2016-01-20 | 益生菌股份公司 | 用于预防和/或治愈细菌性阴道病的包含乳酸菌的组合物 |
CN105362296A (zh) * | 2015-11-27 | 2016-03-02 | 成都吉氧屋科技有限公司 | 乳酸菌洗鼻液 |
CN105687108A (zh) * | 2008-06-13 | 2016-06-22 | 奥洁克公司 | 产过氧化氢细菌用于牙齿增白的用途 |
CN108473944A (zh) * | 2015-09-15 | 2018-08-31 | 庆熙大学校产学协力团 | 具有各种功能的新型乳酸杆菌及其用途 |
CN109069556A (zh) * | 2016-01-19 | 2018-12-21 | 西姆莱斯有限公司 | 用作口腔内抗炎剂的益生菌 |
CN111548970A (zh) * | 2020-05-29 | 2020-08-18 | 江南大学 | 一株能够预防和/或治疗幽门螺杆菌感染的卷曲乳杆菌 |
CN111617025A (zh) * | 2020-06-12 | 2020-09-04 | 洋浦吉商生物科技有限公司 | 美白祛斑抗糖化的发酵产物化妆品 |
CN112236155A (zh) * | 2018-05-31 | 2021-01-15 | 深圳华大生命科学研究院 | 一种组合物及其应用 |
CN112384611A (zh) * | 2018-05-23 | 2021-02-19 | Ko生物技术有限公司 | 卷曲乳杆菌kbl693菌株及其用途 |
CN112469812A (zh) * | 2018-05-23 | 2021-03-09 | Ko生物技术有限公司 | 格氏乳杆菌kbl697菌株及其用途 |
CN113082149A (zh) * | 2021-04-28 | 2021-07-09 | 宋颖鹰 | 植物草本益生菌口腔含片及其制备方法 |
CN117535209A (zh) * | 2024-01-04 | 2024-02-09 | 四川厌氧生物科技有限责任公司 | 左旋短乳杆菌及其在女性生殖道健康中的应用 |
Families Citing this family (65)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8697051B2 (en) * | 1999-06-09 | 2014-04-15 | Vsl Pharmaceuticals Inc. | Composition comprising alkaline sphingomyelinase for use as a dietetic preparation, food supplement or pharmaceutical product |
IT1306716B1 (it) * | 1999-06-21 | 2001-10-02 | Mendes S U R L | Associazione di batteri lattici e suo uso per la prevenzione e/o iltrattamento terapeutico di infezioni e di stati infiammatori. |
HU227086B1 (en) * | 1999-11-25 | 2010-06-28 | Vakcina Kft | Lactobacillus vaccine for treating prostata inflammatory and benign prostata hyperplasia |
JP4603116B2 (ja) * | 1999-12-02 | 2010-12-22 | わかもと製薬株式会社 | 乳酸菌含有組成物、医薬及び食品 |
SE518097C2 (sv) * | 2000-10-03 | 2002-08-27 | Ellen Ab | Förfarande för framställning av en absorberande sanitetsartikel som innefattar mjölksyraproducerande bakterier samt sådant alster |
KR100484480B1 (ko) * | 2001-05-04 | 2005-04-20 | 정 호 김 | 표면 막처리된 락토바실러스 퍼멘텀 yl-3 캡슐 |
EP1287745A1 (en) | 2001-08-24 | 2003-03-05 | The Procter & Gamble Company | Chewable compositions with probiotic agents |
US20040241149A1 (en) * | 2001-09-05 | 2004-12-02 | Claudio De Simone | Use of unmethylatd cpg |
JP4528472B2 (ja) * | 2001-11-29 | 2010-08-18 | ビオフェルミン製薬株式会社 | 歯周病の予防または治療剤 |
US20040071679A1 (en) * | 2002-10-15 | 2004-04-15 | Claudio De Simone | Identifying and treating vaginal infections |
KR100458008B1 (ko) * | 2002-12-02 | 2004-11-18 | 대한민국 | 가축 생산성 향상 유산균 |
EP1481681A1 (en) * | 2003-05-30 | 2004-12-01 | Claudio De Simone | Lactic acid bacteria combination and compositions thereof |
WO2005000034A2 (en) * | 2003-06-23 | 2005-01-06 | Agtech Products, Inc. | Lactic bacteria and its use in direct-fed microbials |
ATE289514T1 (de) * | 2003-11-03 | 2005-03-15 | Peter-Hansen Volkmann | Vaginalpflegezusammensetzung |
US20050158294A1 (en) | 2003-12-19 | 2005-07-21 | The Procter & Gamble Company | Canine probiotic Bifidobacteria pseudolongum |
WO2005085287A1 (en) * | 2004-03-03 | 2005-09-15 | En-N-Tech, Inc. | Treatments for contaminant reduction in lactoferrin preparations and lactoferrin-containing compositions |
SE528382C2 (sv) * | 2004-10-05 | 2006-10-31 | Probi Ab | Probiotiska lactobacillusstammar för förbättrad vaginal hälsa |
EP1880001B1 (en) | 2005-05-31 | 2011-06-08 | The Iams Company | Feline probiotic lactobacilli |
JP4938006B2 (ja) | 2005-05-31 | 2012-05-23 | ザ・アイムス・カンパニー | ネコ科動物プロバイオティク・ビフィドバクテリア |
RU2459864C2 (ru) * | 2005-09-13 | 2012-08-27 | Басф Се | Микроорганизмы, ингибирующие образование неприятного подмышечного запаха |
EP1934328A1 (en) * | 2005-09-19 | 2008-06-25 | Basf Se | Microorganisms inhibiting the formation of foot malodor |
SI1951272T1 (sl) | 2005-10-06 | 2016-10-28 | Probi Ab | Uporaba lactobacillus za zdravljenje virusnih infekcij |
US7563758B2 (en) * | 2005-10-06 | 2009-07-21 | E. I. Du Pont De Nemours And Company | Enzymatic production of peracids using Lactobacilli having perhydrolysis activity |
BRPI0719279B1 (pt) * | 2006-12-19 | 2018-12-04 | Basf Se | uso de um microorganismo pertencendo ao grupo de bactérias do ácido lático ou a um mutante ou derivado do mesmo |
KR20100014523A (ko) * | 2007-02-22 | 2010-02-10 | 위르겐 슈레첸메이르 | 인간의 알레르기 반응을 예방, 억제 또는 제거하는 프로바이오틱 그램-양성 박테리아 |
WO2009021585A1 (en) * | 2007-08-13 | 2009-02-19 | Dsm Ip Assets B.V. | Probiotic bacteria for rducing the occurence of symptoms of winter infections |
KR100898491B1 (ko) * | 2007-10-10 | 2009-05-19 | 주식회사한국야쿠르트 | 사람의 구강 충치균에 저해능이 있는 스트렙토코커스써머필러스 에이취와이9012 및 이를 이용한 식품 |
US9771199B2 (en) | 2008-07-07 | 2017-09-26 | Mars, Incorporated | Probiotic supplement, process for making, and packaging |
KR101100043B1 (ko) | 2009-06-29 | 2011-12-29 | 주식회사한국야쿠르트 | 항염증 효능을 갖는 락토바실러스 플란타룸 에이취와이7711 및 이를 유효성분으로 함유하는 제품 |
US8506952B2 (en) * | 2009-07-03 | 2013-08-13 | James Madison Innovations, Inc. | Probiotic compositions and process thereof |
US10104903B2 (en) | 2009-07-31 | 2018-10-23 | Mars, Incorporated | Animal food and its appearance |
DE202009011379U1 (de) * | 2009-08-24 | 2010-12-30 | Khalifa, Samir | Orale Präparate zur Mund- und Zahnpflege und Bekämpfung von Mundgeruch |
JP4942831B2 (ja) * | 2010-03-19 | 2012-05-30 | 株式会社キティー | 抗アレルギー用組成物 |
KR101062779B1 (ko) | 2010-04-28 | 2011-09-06 | 삼육대학교산학협력단 | 충치 유발 세균의 성장 억제 활성을 나타내는 비피도박테리움 아돌레센티스 spm1005 균주 및 상기 비피도박테리움 아돌레센티스 spm1005 균주 또는 이의 배양물을 유효 성분으로 하는 충치 예방용 식품 및 약제학 조성물 |
KR101068079B1 (ko) * | 2010-07-12 | 2011-09-28 | 삼육대학교산학협력단 | 단순포진바이러스에 대한 항바이러스 활성을 갖는 비피도박테리움 아돌레센티스 spm 0214 및 상기 비피도박테리움 아돌레센티스 spm 0214 균주 또는 이의 배양물을 유효 성분으로 함유하는 단순 포진 바이러스 감염의 예방 또는 치료용 조성물 |
EP2420580A1 (en) * | 2010-08-18 | 2012-02-22 | AB-Biotics, S.A. | Probiotic composition for oral health |
US20130022586A1 (en) * | 2011-07-21 | 2013-01-24 | James Versalovic | Production and use of bacterial histamine |
FR2981273B1 (fr) * | 2011-10-14 | 2013-12-20 | Gilles Andre Yves Bhat | Nouvelle composition pour les muqueuses: tocopherol, macerat huileux de fleurs de calendula dans de l'huile de rose musquee, palmitate de retinol, ubiquinone, ascorbyl palmitate et lactobacillus |
RU2577994C1 (ru) * | 2011-11-30 | 2016-03-20 | Компани Жервэ Данон | Реутерин-вырабатывающие lactobacillus brevis |
RU2494724C2 (ru) * | 2012-01-13 | 2013-10-10 | Владимир Николаевич Иванов | Зубная паста, содержащая лиофилизированную массу живых бифидобактерий |
US20150079039A1 (en) * | 2012-04-13 | 2015-03-19 | The Regents Of The University Of California | Sinusitis diagnostics and treatments |
KR101506995B1 (ko) * | 2012-05-25 | 2015-03-30 | (주)비타바이오 | 오리나무 수피 추출물 및 유산균을 포함하는 항우식성 조성물 |
FR2992973B1 (fr) * | 2012-07-09 | 2015-12-18 | S P M D | Nouvelle souche de lactobacillus crispatus |
RU2504580C1 (ru) * | 2012-08-01 | 2014-01-20 | Вячеслав Михайлович Абрамов | ПРОБИОТИЧЕСКИЕ ШТАММЫ Lactobacillus И ИХ КОНСОРЦИУМ ДЛЯ ПРОФИЛАКТИКИ И ЛЕЧЕНИЯ УРОГЕНИТАЛЬНЫХ ИНФЕКЦИОННЫХ ЗАБОЛЕВАНИЙ У ЖЕНЩИН |
US9655839B2 (en) | 2013-02-14 | 2017-05-23 | University Of Florida Research Foundation, Inc. | Probiotic arginolytic oral compositions and methods of making and using probiotic arginolytic oral compositions |
US10206959B2 (en) | 2013-02-14 | 2019-02-19 | University Of Florida Research Foundation, Inc. | Probiotic arginolytic oral compositions and methods of making and using probiotic arginolytic oral compositions |
KR20160022909A (ko) | 2013-06-27 | 2016-03-02 | 스타벅스 코포레이션 디/비/에이 스타벅스 커피 컴퍼니 | 음료 및 다른 식품들을 위한 생물보존 방법 |
PL3016667T3 (pl) * | 2013-07-05 | 2023-02-06 | Stellar Biome Inc. | Probiotyczne szczepy bakteryjne do zapobiegania i leczenia chorób w jamie ustnej |
CN104694414B (zh) * | 2014-11-21 | 2019-05-24 | 北京百益恒源科技有限公司 | 一株詹氏乳酸杆菌(Lactobacillus jensenii)及其制药用途 |
KR101980252B1 (ko) | 2015-05-26 | 2019-05-21 | (주)투라인스 | 질증 치료용 조성물 |
RU2619281C2 (ru) * | 2015-07-24 | 2017-05-15 | Федеральное государственное бюджетное научное учреждение Всероссийский научно-исследовательский институт технологии консервирования | Способ выработки ферментированного растительного сырья |
WO2017034460A1 (en) * | 2015-08-25 | 2017-03-02 | Shahram Aghaibeik-Lavasani | Composition and method for treatment and prophylaxis of intestinal infection and inflammation |
GB201600975D0 (en) | 2016-01-19 | 2016-03-02 | Probi Ab | Novel strain of probiotic bacteria and compositions and uses thereof |
EP3196318A1 (en) | 2016-01-19 | 2017-07-26 | Symrise AG | Probiotics for altering the composition of oral biofilms |
KR101720145B1 (ko) * | 2016-07-08 | 2017-04-07 | (주)정가진면역연구소 | 여성 질염 예방 및 개선 기능성 조성물 |
EP3351259A1 (en) | 2017-01-18 | 2018-07-25 | Symrise AG | Probiotics for aggregation with disease-associated species in the oral cavity |
EP3517119B1 (en) | 2018-01-26 | 2021-08-11 | Probisearch, S.L.U. | Composition comprising new lactobacillus salivarius strain and method for the prevention and treatment of otitis and upper respiratory infections |
RU2675110C1 (ru) * | 2018-04-09 | 2018-12-17 | Федеральное государственное бюджетное учреждение науки Институт общей генетики им. Н.И. Вавилова Российской академии наук (ИОГЕН РАН) | Фармацевтическая композиция для терапии воспалительных заболеваний слизистых оболочек кишечника на основе штамма Lactobacillus brevis 47f, проявляющая местную противовоспалительную активность |
KR102164906B1 (ko) * | 2018-09-12 | 2020-10-14 | (주)성운파마코피아 | 락토바실러스 살리바리우스 swpm101 및 락토바실러스 가세리 swpm102를 포함하는 골질환의 예방, 개선 또는 치료용 조성물 |
KR102063554B1 (ko) | 2018-09-12 | 2020-01-09 | (주)성운파마코피아 | 항진균 활성 또는 항균 활성을 갖는 락토바실러스 가세리 swpm102 |
CA3124725A1 (en) * | 2018-10-10 | 2020-04-16 | Servatus Ltd | Methods of treatment of inflammatory conditions and associated infections |
CN111088178B (zh) * | 2018-10-23 | 2022-11-22 | 上海上药信谊药厂有限公司 | 一种产乳酸和h2o2的乳杆菌及其应用 |
KR102364448B1 (ko) * | 2019-12-31 | 2022-02-17 | 심민보 | 프로바이오틱스 및 항생제를 포함하는 항염증용 약학적 조성물 및 이를 이용한 방법 |
KR102162470B1 (ko) | 2020-03-19 | 2020-10-06 | 주식회사 비피도 | 비피도박테리움 슈도카테눌라튬 c-rapo (kctc13986bp), 비피도박테리움 비피덤 att (kctc13474bp) 균주를 포함하는 쇼그렌증후군 억제용 식품 조성물 및 약학 조성물 |
KR102646766B1 (ko) * | 2023-06-14 | 2024-03-13 | 일동바이오사이언스(주) | 잇몸 질환을 예방하고 구취 생성 억제능을 가지는 비피도박테리움 브레베 idcc 4401 균주를 포함하는 조성물 및 건강기능식품 |
Family Cites Families (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS60190707A (ja) * | 1984-03-09 | 1985-09-28 | Advance Res & Dev Co Ltd | 抗う蝕剤 |
JPS6191126A (ja) * | 1984-10-09 | 1986-05-09 | Advance Res & Dev Co Ltd | 抗歯周症剤 |
US5804179A (en) * | 1985-12-31 | 1998-09-08 | Research Corporation Technologies, Inc. | Lactobacillus compositions and methods for treating urinary tract infections |
US5413960A (en) * | 1987-05-01 | 1995-05-09 | Biogaia Ab | Antibiotic reuterin |
US5286478A (en) * | 1987-11-04 | 1994-02-15 | Rhone-Poulenc Chimie | Dentifrice-compatible silica particulates |
IT1227154B (it) * | 1988-08-05 | 1991-03-19 | A Tosi Farmaceutici S R L Nova | Composizioni farmaceutiche per uso ginecologico a base di lattobacilli |
IT1254210B (it) * | 1992-02-10 | 1995-09-14 | Simone Claudio De | Composizioni dietetiche e/o farmaceutiche a base di batteri lattici liofilizzati, loro preparazione e impiego |
RU2031586C1 (ru) * | 1993-02-05 | 1995-03-27 | Тамара Георгиевна Извекова | Биологически активный кисломолочный продукт "ацидолакт-наринэ" и способ его получения |
WO1994019950A1 (en) * | 1993-03-10 | 1994-09-15 | Commonwealth Scientific And Industrial Research Organisation | Biocontrol agents for use in agriculture |
US5747026A (en) * | 1993-10-15 | 1998-05-05 | University Of Alabama At Birmingham Research Foundation | Antioxidants |
ATE187769T1 (de) * | 1994-05-27 | 2000-01-15 | Agrano Ag | Verfahren zur herstellung von kulturmedien, welche für die individuelle kultur von hefen und milchsäurebakterien oder die kokultur von hefen und milchsäurebakterien verwendbar sind. |
JP3004890B2 (ja) * | 1995-03-28 | 2000-01-31 | 雪印乳業株式会社 | 病原体感染防御剤 |
JPH08298982A (ja) * | 1995-05-02 | 1996-11-19 | Aasu Giken:Kk | 複合微生物製剤 |
CA2245810A1 (en) * | 1996-02-14 | 1997-08-21 | The Procter & Gamble Company | Urogenital and intestinal compositions |
JP4021951B2 (ja) * | 1996-03-01 | 2007-12-12 | わかもと製薬株式会社 | 乳酸菌を有効成分とする抗胃炎剤、抗潰瘍剤および醗酵食品 |
IT1283225B1 (it) * | 1996-03-11 | 1998-04-16 | Renata Maria Anna Ve Cavaliere | Ceppi di batteri, composizione farmaceutica contenente uno o piu' di tali ceppi e uso dei medesimi per la prevenzione e la terapia delle |
DE69600525T2 (de) * | 1996-12-23 | 1998-12-10 | Sitia Yomo Spa | Lyophilisierte, lebende Bakerien enthaltende Nahrungszusammensetzung |
JP3028214B2 (ja) * | 1997-06-03 | 2000-04-04 | カルピス株式会社 | 鳥類用生菌剤の投与方法 |
KR100266752B1 (ko) * | 1997-08-07 | 2001-03-02 | 오종석 | 인체 구강내 치태형성을 억제하는 신규한 유산균 |
IT1298918B1 (it) * | 1998-02-20 | 2000-02-07 | Mendes Srl | Uso di batteri dotati di arginina deiminasi per indurre apoptosi e/o ridurre una reazione infiammatoria e composizioni farmaceutiche |
PT956858E (pt) * | 1998-04-30 | 2002-04-29 | Renata Maria Anna Caval Vesely | Composicoes farmaceuticas contendo lactobacilos para o tratamento de infeccoes vaginais |
IT1306716B1 (it) * | 1999-06-21 | 2001-10-02 | Mendes S U R L | Associazione di batteri lattici e suo uso per la prevenzione e/o iltrattamento terapeutico di infezioni e di stati infiammatori. |
-
1999
- 1999-06-21 IT IT1999RM000400A patent/IT1306716B1/it active
-
2000
- 2000-06-16 EE EEP200100682A patent/EE04620B1/xx not_active IP Right Cessation
- 2000-06-16 WO PCT/IT2000/000251 patent/WO2000078322A2/en active IP Right Grant
- 2000-06-16 UA UA2002010459A patent/UA76696C2/uk unknown
- 2000-06-16 HU HU0202051A patent/HUP0202051A3/hu unknown
- 2000-06-16 JP JP2001504385A patent/JP4949580B2/ja not_active Expired - Fee Related
- 2000-06-16 BR BRPI0017622A patent/BRPI0017622B1/pt not_active IP Right Cessation
- 2000-06-16 PT PT00940762T patent/PT1194525E/pt unknown
- 2000-06-16 DK DK00940762T patent/DK1194525T3/da active
- 2000-06-16 AT AT00940762T patent/ATE325614T1/de not_active IP Right Cessation
- 2000-06-16 ES ES00940762T patent/ES2262522T3/es not_active Expired - Lifetime
- 2000-06-16 TR TR2001/03606T patent/TR200103606T2/xx unknown
- 2000-06-16 SI SI200030866T patent/SI1194525T1/sl unknown
- 2000-06-16 NZ NZ516022A patent/NZ516022A/en unknown
- 2000-06-16 BR BRPI0011799A patent/BRPI0011799B1/pt not_active IP Right Cessation
- 2000-06-16 IL IL14688900A patent/IL146889A0/xx unknown
- 2000-06-16 EA EA200200059A patent/EA006037B1/ru not_active IP Right Cessation
- 2000-06-16 CZ CZ20014220A patent/CZ298682B6/cs not_active IP Right Cessation
- 2000-06-16 EP EP00940762A patent/EP1194525B1/en not_active Expired - Lifetime
- 2000-06-16 CA CA2373375A patent/CA2373375C/en not_active Expired - Fee Related
- 2000-06-16 DZ DZ003167A patent/DZ3167A1/xx active
- 2000-06-16 CN CNB008093091A patent/CN1227354C/zh not_active Expired - Fee Related
- 2000-06-16 PL PL00352805A patent/PL352805A1/xx unknown
- 2000-06-16 SK SK1717-2001A patent/SK17172001A3/sk unknown
- 2000-06-16 DE DE60027894T patent/DE60027894T2/de not_active Expired - Lifetime
- 2000-06-16 MX MXPA01013239 patent/MX236443B/es active IP Right Grant
- 2000-06-16 KR KR1020017016367A patent/KR100712286B1/ko active IP Right Grant
- 2000-06-16 AU AU55660/00A patent/AU775452B2/en not_active Ceased
- 2000-06-21 AR ARP000103077A patent/AR024579A1/es not_active Application Discontinuation
-
2001
- 2001-11-21 MA MA26418A patent/MA25775A1/fr unknown
- 2001-11-23 IN IN1233KO2001 patent/IN2001KO01233A/en unknown
- 2001-11-27 IS IS6177A patent/IS6177A/is unknown
- 2001-12-03 IL IL146889A patent/IL146889A/en not_active IP Right Cessation
- 2001-12-20 NO NO20016291A patent/NO329324B1/no not_active IP Right Cessation
- 2001-12-21 US US10/024,199 patent/US7052688B2/en not_active Expired - Lifetime
-
2002
- 2002-01-18 ZA ZA200200461A patent/ZA200200461B/en unknown
- 2002-11-29 HK HK02108628.1A patent/HK1047132B/zh not_active IP Right Cessation
-
2012
- 2012-01-05 JP JP2012000774A patent/JP5969764B2/ja not_active Expired - Lifetime
- 2012-06-05 AR ARP120101984A patent/AR086677A2/es unknown
-
2014
- 2014-10-02 JP JP2014204243A patent/JP6043325B2/ja not_active Expired - Lifetime
Cited By (37)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1860219B (zh) * | 2003-01-29 | 2011-07-20 | 生命大地女神有限公司 | 乳酸杆菌在减少龋齿和细菌引发龋齿中的用途 |
CN102389390A (zh) * | 2003-08-11 | 2012-03-28 | 奥洁克公司 | 维持口腔健康的组合物及方法 |
CN101043856B (zh) * | 2004-12-23 | 2010-05-12 | 艾蒂尔药物有限公司 | 用于鉴定和治疗阴道疾病的装置和方法 |
CN100556414C (zh) * | 2005-10-14 | 2009-11-04 | 德阳创新生物工程有限公司 | 一种具免疫调节功能的多菌组合物及其制备方法与用途 |
CN104277998B (zh) * | 2008-06-11 | 2021-02-02 | 巴斯夫欧洲公司 | 用于预防和/或治疗口腔恶臭的用途和方法 |
CN104277998A (zh) * | 2008-06-11 | 2015-01-14 | 巴斯夫欧洲公司 | 用于预防和/或治疗口腔恶臭的用途和方法 |
CN105687108A (zh) * | 2008-06-13 | 2016-06-22 | 奥洁克公司 | 产过氧化氢细菌用于牙齿增白的用途 |
CN104023732A (zh) * | 2011-08-05 | 2014-09-03 | 株式会社养乐多本社 | 口腔疾患的预防或治疗剂 |
CN104023732B (zh) * | 2011-08-05 | 2017-09-01 | 株式会社养乐多本社 | 口腔疾患的预防或治疗剂 |
CN102690768B (zh) * | 2012-05-31 | 2014-07-30 | 江南大学 | 一株短乳杆菌及其应用 |
CN102690768A (zh) * | 2012-05-31 | 2012-09-26 | 江南大学 | 一株短乳杆菌及其应用 |
CN102727531A (zh) * | 2012-07-23 | 2012-10-17 | 郑州金森生物科技工程有限公司 | 一种对阴道炎具有治疗和预防作用的活性乳酸菌胶囊 |
CN104769100A (zh) * | 2012-10-25 | 2015-07-08 | 热尔韦·达诺尼公司 | 用于治疗幽门螺杆菌感染的嗜热链球菌菌株 |
CN103409334A (zh) * | 2013-01-16 | 2013-11-27 | 生合生物科技股份有限公司 | 抑制阴道炎病原菌之乳酸杆菌及其用途 |
CN105263504A (zh) * | 2013-05-14 | 2016-01-20 | 益生菌股份公司 | 用于预防和/或治愈细菌性阴道病的包含乳酸菌的组合物 |
CN104957260A (zh) * | 2014-03-07 | 2015-10-07 | 内蒙古伊利实业集团股份有限公司 | 具有缓解咽喉部炎症功效的益生菌食品组合物及食品 |
CN103798392B (zh) * | 2014-03-07 | 2015-12-30 | 内蒙古伊利实业集团股份有限公司 | 具有缓解咽喉部炎症功效的益生菌食品组合物及食品 |
CN103798392A (zh) * | 2014-03-07 | 2014-05-21 | 内蒙古伊利实业集团股份有限公司 | 具有缓解咽喉部炎症功效的益生菌食品组合物及食品 |
CN104957260B (zh) * | 2014-03-07 | 2018-07-24 | 内蒙古伊利实业集团股份有限公司 | 具有缓解咽喉部炎症功效的益生菌食品组合物及食品 |
CN104232537A (zh) * | 2014-09-03 | 2014-12-24 | 中国科学院微生物研究所 | 一株弯曲乳杆菌及其应用 |
CN104293718A (zh) * | 2014-10-11 | 2015-01-21 | 中国科学院微生物研究所 | 一株詹氏乳杆菌及其应用 |
CN104622914A (zh) * | 2015-01-06 | 2015-05-20 | 占美华 | 阴道益生菌栓 |
CN108473944A (zh) * | 2015-09-15 | 2018-08-31 | 庆熙大学校产学协力团 | 具有各种功能的新型乳酸杆菌及其用途 |
CN108473944B (zh) * | 2015-09-15 | 2022-02-25 | 庆熙大学校产学协力团 | 具有各种功能的新型乳酸杆菌及其用途 |
CN105362296A (zh) * | 2015-11-27 | 2016-03-02 | 成都吉氧屋科技有限公司 | 乳酸菌洗鼻液 |
CN109069556A (zh) * | 2016-01-19 | 2018-12-21 | 西姆莱斯有限公司 | 用作口腔内抗炎剂的益生菌 |
CN112469812A (zh) * | 2018-05-23 | 2021-03-09 | Ko生物技术有限公司 | 格氏乳杆菌kbl697菌株及其用途 |
CN112384611A (zh) * | 2018-05-23 | 2021-02-19 | Ko生物技术有限公司 | 卷曲乳杆菌kbl693菌株及其用途 |
CN112384611B (zh) * | 2018-05-23 | 2024-01-09 | Ko生物技术有限公司 | 卷曲乳杆菌kbl693菌株及其用途 |
CN112469812B (zh) * | 2018-05-23 | 2024-01-12 | Ko生物技术有限公司 | 格氏乳杆菌kbl697菌株及其用途 |
CN112236155A (zh) * | 2018-05-31 | 2021-01-15 | 深圳华大生命科学研究院 | 一种组合物及其应用 |
CN111548970B (zh) * | 2020-05-29 | 2021-03-26 | 江南大学 | 一株能够预防和/或治疗幽门螺杆菌感染的卷曲乳杆菌 |
CN111548970A (zh) * | 2020-05-29 | 2020-08-18 | 江南大学 | 一株能够预防和/或治疗幽门螺杆菌感染的卷曲乳杆菌 |
CN111617025A (zh) * | 2020-06-12 | 2020-09-04 | 洋浦吉商生物科技有限公司 | 美白祛斑抗糖化的发酵产物化妆品 |
CN113082149A (zh) * | 2021-04-28 | 2021-07-09 | 宋颖鹰 | 植物草本益生菌口腔含片及其制备方法 |
CN117535209A (zh) * | 2024-01-04 | 2024-02-09 | 四川厌氧生物科技有限责任公司 | 左旋短乳杆菌及其在女性生殖道健康中的应用 |
CN117535209B (zh) * | 2024-01-04 | 2024-03-29 | 四川厌氧生物科技有限责任公司 | 左旋短乳杆菌及其在女性生殖道健康中的应用 |
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN1227354C (zh) | 乳酸细菌的组合及其用于预防和/或治疗感染和炎症的用途 | |
CN1211189A (zh) | 含衍自杜鹃花科植物的物质和乳酸菌生长因子的,用于泌尿生殖系统和肠道疾病的组合物 | |
CN1211188A (zh) | 用于泌尿生殖道和肠道疾病的组合物 | |
CN108738308B (zh) | 新颖的胚芽乳杆菌益生菌菌株和其组合物及其在炎症治疗中的用途 | |
JP2003502375A5 (zh) | ||
JP2010053062A (ja) | 口腔用組成物 | |
JP2019502397A (ja) | 口腔バイオフィルムの組成を変化させるプロバイオティクス | |
TW200400262A (en) | Antimicrobial composition | |
CN1863464A (zh) | 维持口腔健康的组合物及方法 | |
TWI842366B (zh) | 抑制植體周圍炎的組成物及其用途 | |
US20240100130A1 (en) | Water soluble composition and production method thereof | |
KR102630615B1 (ko) | 신규한 엔테로코커스 패칼리스 균주 및 락토코커스 락티스 균주, 및 이의 유청 발효물을 포함하는 구강질환 또는 대장질환의 예방 또는 개선용 식품 조성물 | |
JP2008120719A (ja) | 瀉下剤 | |
CN118141842A (zh) | 益生菌组合物在制备用于治疗肠道感染症状的药物中的用途 | |
CN115554320A (zh) | 一株能够缓解牙周炎的发酵乳杆菌灭活菌体及其应用 | |
CN118146972A (zh) | 一种改善口腔健康的瑞士乳杆菌及益生菌组合物 | |
Punia et al. | The Mechanism Of Action Of Probiotics: Current Opinion In Oral Health. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
ASS | Succession or assignment of patent right |
Owner name: ESTELLE PHARM PUR GMBH Free format text: FORMER OWNER: VSL PHARMACEUTICALS LTD Effective date: 20050513 |
|
C41 | Transfer of patent application or patent right or utility model | ||
TA01 | Transfer of patent application right |
Effective date of registration: 20050513 Address after: Portugal Funchal Applicant after: Actial Farmaceutica Lda. Address before: Dublin, Ireland Applicant before: VSL Pharmaceutical Ltd. |
|
C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
C56 | Change in the name or address of the patentee | ||
CP02 | Change in the address of a patent holder |
Address after: Rome Italy Patentee after: Actial Farmaceutica Lda. Address before: Portugal Funchal Patentee before: Actial Farmaceutica Lda. |
|
CF01 | Termination of patent right due to non-payment of annual fee | ||
CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20051116 Termination date: 20170616 |