CN112236155A - 一种组合物及其应用 - Google Patents

一种组合物及其应用 Download PDF

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Publication number
CN112236155A
CN112236155A CN201880093363.0A CN201880093363A CN112236155A CN 112236155 A CN112236155 A CN 112236155A CN 201880093363 A CN201880093363 A CN 201880093363A CN 112236155 A CN112236155 A CN 112236155A
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composition
food
inflammation
bacteria
lactobacillus
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邹远强
薛文斌
肖亮
李晓平
余靖宏
刘传
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BGI Shenzhen Co Ltd
Shenzhen BGI Life Science Research Institute
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BGI Shenzhen Co Ltd
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

一种组合物及其应用。该组合物，包括加氏乳杆菌和/或其代谢产物，以及嗜酸乳杆菌和/或其代谢产物。该组合物，通过加氏乳杆菌和嗜酸乳杆菌两者联合使用，能够对炎症，尤其是溃疡性肠炎，及其相关疾病有良好的治疗和预防效果，为炎症及其相关疾病的治疗和预防提供了一种安全、有效、毒副作用小，且不易产生抗性的组合物。

Description

PCT国内申请，说明书已公开。

Claims (28)

  1. PCT国内申请，权利要求书已公开。
CN201880093363.0A 2018-05-31 2018-05-31 一种组合物及其应用 Pending CN112236155A (zh)

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PCT/CN2018/089317 WO2019227417A1 (zh) 2018-05-31 2018-05-31 一种组合物及其应用

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CN112236155A true CN112236155A (zh) 2021-01-15

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WO (1) WO2019227417A1 (zh)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111093682B (zh) * 2017-12-08 2024-01-16 深圳华大生命科学研究院 丁酸杆菌(Butyribacter intestini)在预防和/或治疗炎症相关疾病的应用

Citations (16)

* Cited by examiner, † Cited by third party
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CN1357038A (zh) * 1999-06-21 2002-07-03 Vsl制药有限公司 乳酸细菌的组合及其用于预防和/或治疗感染和炎症的用途
JP2003095963A (ja) * 2001-09-20 2003-04-03 Snow Brand Milk Prod Co Ltd 炎症性腸疾患及び過敏性腸症候群の予防・治療剤
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CA2683912A1 (en) * 2007-04-11 2008-10-23 Biogaia Ab Use of selected lactic acid bacteria for reducing atherosclerosis
CN101575582A (zh) * 2008-05-08 2009-11-11 景岳生物科技股份有限公司 具有抗炎活性的乳杆菌分离株及其用途
CN102115721A (zh) * 2008-05-08 2011-07-06 景岳生物科技股份有限公司 具有抗炎活性的乳杆菌分离株及其用途
TW201200142A (en) * 2008-04-30 2012-01-01 Genmont Biotech Inc Lactobacillus isolates having anti-inflammatory activities and uses of the same
CN104187710A (zh) * 2014-07-28 2014-12-10 胡安然 炎性肠病全营养配方食品
CN104413334A (zh) * 2013-08-30 2015-03-18 深圳华大基因科技有限公司 可食用组合物及其制备方法和用途
CN104740138A (zh) * 2013-12-31 2015-07-01 深圳华大基因科技有限公司 包含芦荟、益生菌和益生元的组合物及其用途
CN105029407A (zh) * 2015-04-14 2015-11-11 劲膳美生物科技股份有限公司 炎性肠病医学配方食品
CN105163747A (zh) * 2011-04-20 2015-12-16 G·莫格纳 能够恢复在胃酸过多的药物治疗期间丧失的胃的屏障效应的包含益生菌的组合物
CN105343133A (zh) * 2015-12-08 2016-02-24 东北农业大学 一种治疗溃疡性结肠炎的复合益生菌、药物及其制备方法
WO2016038198A1 (en) * 2014-09-12 2016-03-17 Swecure Ab Use of collinsella for treatment of inflammatory bowel disease
CN106479906A (zh) * 2015-08-27 2017-03-08 深圳华大基因研究院 肠道细菌丁酸杆菌（Butyribacter intestini)及其应用
CN108064132A (zh) * 2014-10-31 2018-05-22 霍勒拜欧姆公司 与病症的微生物治疗和诊断有关的方法和组合物

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105343132B (zh) * 2015-12-08 2019-04-26 东北农业大学 治疗结肠炎的组合物、药物及其制备方法

Patent Citations (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1357038A (zh) * 1999-06-21 2002-07-03 Vsl制药有限公司 乳酸细菌的组合及其用于预防和/或治疗感染和炎症的用途
JP2003095963A (ja) * 2001-09-20 2003-04-03 Snow Brand Milk Prod Co Ltd 炎症性腸疾患及び過敏性腸症候群の予防・治療剤
CN1663573A (zh) * 2004-03-04 2005-09-07 青岛东海药业有限公司 一种稳定安全的微生态制剂及其制备方法和用途
CA2683912A1 (en) * 2007-04-11 2008-10-23 Biogaia Ab Use of selected lactic acid bacteria for reducing atherosclerosis
TW201200142A (en) * 2008-04-30 2012-01-01 Genmont Biotech Inc Lactobacillus isolates having anti-inflammatory activities and uses of the same
CN101575582A (zh) * 2008-05-08 2009-11-11 景岳生物科技股份有限公司 具有抗炎活性的乳杆菌分离株及其用途
CN102115721A (zh) * 2008-05-08 2011-07-06 景岳生物科技股份有限公司 具有抗炎活性的乳杆菌分离株及其用途
CN105163747A (zh) * 2011-04-20 2015-12-16 G·莫格纳 能够恢复在胃酸过多的药物治疗期间丧失的胃的屏障效应的包含益生菌的组合物
CN104413334A (zh) * 2013-08-30 2015-03-18 深圳华大基因科技有限公司 可食用组合物及其制备方法和用途
CN104740138A (zh) * 2013-12-31 2015-07-01 深圳华大基因科技有限公司 包含芦荟、益生菌和益生元的组合物及其用途
CN104187710A (zh) * 2014-07-28 2014-12-10 胡安然 炎性肠病全营养配方食品
WO2016038198A1 (en) * 2014-09-12 2016-03-17 Swecure Ab Use of collinsella for treatment of inflammatory bowel disease
CN108064132A (zh) * 2014-10-31 2018-05-22 霍勒拜欧姆公司 与病症的微生物治疗和诊断有关的方法和组合物
CN105029407A (zh) * 2015-04-14 2015-11-11 劲膳美生物科技股份有限公司 炎性肠病医学配方食品
CN106479906A (zh) * 2015-08-27 2017-03-08 深圳华大基因研究院 肠道细菌丁酸杆菌（Butyribacter intestini)及其应用
CN105343133A (zh) * 2015-12-08 2016-02-24 东北农业大学 一种治疗溃疡性结肠炎的复合益生菌、药物及其制备方法

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
史佳鹭等: "益生菌对免疫细胞的影响及其在自身免疫性疾病中的应用", 《食品工业科技》 *

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Application publication date: 20210115

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Denomination of invention: A composition and its application

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Record date: 20221107