BRPI0412125A - molécula de ácido nucleico isolada, polipeptìdeo de fusão, vetor de expressão, método de produzir um polipeptìdeo de fusão de vegf, captador de fator de crescimento de célula endotelial vascular, composição farmacêutica, método de tratar uma doença ou condição que são restabelecidas, melhoradas ou inibidas pela remoção ou inibição do fator de crescimento endotelial vascular, e, artigo de fabricação - Google Patents

molécula de ácido nucleico isolada, polipeptìdeo de fusão, vetor de expressão, método de produzir um polipeptìdeo de fusão de vegf, captador de fator de crescimento de célula endotelial vascular, composição farmacêutica, método de tratar uma doença ou condição que são restabelecidas, melhoradas ou inibidas pela remoção ou inibição do fator de crescimento endotelial vascular, e, artigo de fabricação

Info

Publication number
BRPI0412125A
BRPI0412125A BRPI0412125-2A BRPI0412125A BRPI0412125A BR PI0412125 A BRPI0412125 A BR PI0412125A BR PI0412125 A BRPI0412125 A BR PI0412125A BR PI0412125 A BRPI0412125 A BR PI0412125A
Authority
BR
Brazil
Prior art keywords
growth factor
vascular endothelial
fusion polypeptide
vegf
nucleic acid
Prior art date
Application number
BRPI0412125-2A
Other languages
English (en)
Inventor
Thomas J Daly
James P Fandl
Nicholas J Papadopoulos
Original Assignee
Regeneron Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=33552268&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0412125(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Regeneron Pharma filed Critical Regeneron Pharma
Publication of BRPI0412125A publication Critical patent/BRPI0412125A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Ophthalmology & Optometry (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)

Abstract

"MOLéCULA DE áCIDO NUCLEICO ISOLADA, POLIPEPTìDEO DE FUSãO, VETOR DE EXPRESSãO, MéTODO DE PRODUZIR UM POLIPEPTìDEO DE FUSãO DE VEGF, CAPTADOR DE FATOR DE CRESCIMENTO DE CéLULA ENDOTELIAL VASCULAR, COMPOSIçãO FARMACêUTICA, MéTODO DE TRATAR UMA DOENçA OU CONDIçãO QUE SãO RESTABELECIDAS, MELHORADAS OU INIBIDAS PELA REMOçãO OU INIBIçãO DO FATOR DE CRESCIMENTO ENDOTELIAL VASCULAR, E, ARTIGO DE FABRICAçãO". As moléculas de ácido nucleico e as proteínas multiméricas capazes de ligar o fator de crescimento endotelial vascular (VEGF). Captadores de VEGF são divulgados que são terapeuticamente úteis para tratar condições e doenças associadas com o VEGF e são especificamente planejadas para a administração local aos órgãos, tecidos e/ou células específicos.
BRPI0412125-2A 2003-06-30 2004-06-29 molécula de ácido nucleico isolada, polipeptìdeo de fusão, vetor de expressão, método de produzir um polipeptìdeo de fusão de vegf, captador de fator de crescimento de célula endotelial vascular, composição farmacêutica, método de tratar uma doença ou condição que são restabelecidas, melhoradas ou inibidas pela remoção ou inibição do fator de crescimento endotelial vascular, e, artigo de fabricação BRPI0412125A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/609,775 US7087411B2 (en) 1999-06-08 2003-06-30 Fusion protein capable of binding VEGF
PCT/US2004/021059 WO2005000895A2 (en) 2003-06-30 2004-06-29 Vegf traps and therapeutic uses thereof

Publications (1)

Publication Number Publication Date
BRPI0412125A true BRPI0412125A (pt) 2006-08-15

Family

ID=33552268

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0412125-2A BRPI0412125A (pt) 2003-06-30 2004-06-29 molécula de ácido nucleico isolada, polipeptìdeo de fusão, vetor de expressão, método de produzir um polipeptìdeo de fusão de vegf, captador de fator de crescimento de célula endotelial vascular, composição farmacêutica, método de tratar uma doença ou condição que são restabelecidas, melhoradas ou inibidas pela remoção ou inibição do fator de crescimento endotelial vascular, e, artigo de fabricação

Country Status (29)

Country Link
US (4) US7087411B2 (pt)
EP (2) EP1639007B1 (pt)
JP (2) JP2007528708A (pt)
KR (1) KR101131429B1 (pt)
CN (1) CN1816566B (pt)
AR (1) AR044938A1 (pt)
AT (2) ATE427962T1 (pt)
AU (1) AU2004252175B2 (pt)
BR (1) BRPI0412125A (pt)
CA (1) CA2529660C (pt)
CY (2) CY1109204T1 (pt)
DE (2) DE602004029833D1 (pt)
DK (2) DK1639007T3 (pt)
ES (2) ES2354847T3 (pt)
HK (1) HK1082511A1 (pt)
IL (2) IL172404A (pt)
MX (1) MXPA05013641A (pt)
MY (1) MY154826A (pt)
NO (1) NO339766B1 (pt)
NZ (2) NZ572107A (pt)
PL (2) PL1947118T3 (pt)
PT (2) PT1947118E (pt)
RU (1) RU2376373C2 (pt)
SI (2) SI1947118T1 (pt)
TW (1) TWI330197B (pt)
UA (2) UA90657C2 (pt)
UY (1) UY28396A1 (pt)
WO (1) WO2005000895A2 (pt)
ZA (1) ZA200600157B (pt)

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* Cited by examiner, † Cited by third party
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US20090062200A1 (en) 2009-03-05
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US20040014667A1 (en) 2004-01-22
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