ZA987394B - Process for selective derivatization of taxanes - Google Patents
Process for selective derivatization of taxanesInfo
- Publication number
- ZA987394B ZA987394B ZA987394A ZA987394A ZA987394B ZA 987394 B ZA987394 B ZA 987394B ZA 987394 A ZA987394 A ZA 987394A ZA 987394 A ZA987394 A ZA 987394A ZA 987394 B ZA987394 B ZA 987394B
- Authority
- ZA
- South Africa
- Prior art keywords
- sup
- taxanes
- hydroxytaxane
- acyloxy
- selective derivatization
- Prior art date
Links
- 229940123237 Taxane Drugs 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 3
- 238000001212 derivatisation Methods 0.000 title 1
- 125000001183 hydrocarbyl group Chemical group 0.000 abstract 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- DHKHKXVYLBGOIT-UHFFFAOYSA-N acetaldehyde Diethyl Acetal Natural products CCOC(C)OCC DHKHKXVYLBGOIT-UHFFFAOYSA-N 0.000 abstract 1
- 125000002777 acetyl group Chemical class [H]C([H])([H])C(*)=O 0.000 abstract 1
- 239000003377 acid catalyst Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 125000001072 heteroaryl group Chemical group 0.000 abstract 1
- DKPFODGZWDEEBT-QFIAKTPHSA-N taxane Chemical class C([C@]1(C)CCC[C@@H](C)[C@H]1C1)C[C@H]2[C@H](C)CC[C@@H]1C2(C)C DKPFODGZWDEEBT-QFIAKTPHSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
- C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
- C07F7/1872—Preparation; Treatments not provided for in C07F7/20
- C07F7/1892—Preparation; Treatments not provided for in C07F7/20 by reactions not provided for in C07F7/1876 - C07F7/1888
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epoxy Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Saccharide Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Soil Working Implements (AREA)
- Fats And Perfumes (AREA)
- Percussion Or Vibration Massage (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US5600097P | 1997-08-18 | 1997-08-18 | |
US8126598P | 1998-04-09 | 1998-04-09 | |
US09/063,477 US7288665B1 (en) | 1997-08-18 | 1998-04-20 | Process for selective derivatization of taxanes |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA987394B true ZA987394B (en) | 1999-05-14 |
Family
ID=27368950
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA987394A ZA987394B (en) | 1997-08-18 | 1998-08-17 | Process for selective derivatization of taxanes |
Country Status (25)
Country | Link |
---|---|
US (5) | US7288665B1 (fr) |
EP (6) | EP1170292B1 (fr) |
JP (1) | JP2001504864A (fr) |
KR (1) | KR100596989B1 (fr) |
CN (3) | CN1205196C (fr) |
AT (3) | ATE326455T1 (fr) |
AU (1) | AU744987B2 (fr) |
BR (1) | BR9806145A (fr) |
CA (2) | CA2268662A1 (fr) |
CY (1) | CY1105399T1 (fr) |
CZ (1) | CZ296580B6 (fr) |
DE (3) | DE69837684T2 (fr) |
DK (3) | DK1170293T3 (fr) |
ES (3) | ES2274579T3 (fr) |
HU (1) | HUP0300425A3 (fr) |
ID (1) | ID21654A (fr) |
IL (3) | IL129386A0 (fr) |
NO (4) | NO325139B1 (fr) |
NZ (1) | NZ335156A (fr) |
PL (3) | PL193674B1 (fr) |
PT (3) | PT956284E (fr) |
RU (1) | RU2225402C2 (fr) |
SG (1) | SG97986A1 (fr) |
WO (1) | WO1999009021A1 (fr) |
ZA (1) | ZA987394B (fr) |
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-
1998
- 1998-04-20 US US09/063,477 patent/US7288665B1/en not_active Expired - Fee Related
- 1998-08-17 ES ES98942080T patent/ES2274579T3/es not_active Expired - Lifetime
- 1998-08-17 AU AU90211/98A patent/AU744987B2/en not_active Ceased
- 1998-08-17 JP JP51349899A patent/JP2001504864A/ja not_active Ceased
- 1998-08-17 WO PCT/US1998/017016 patent/WO1999009021A1/fr active Application Filing
- 1998-08-17 SG SG200006873A patent/SG97986A1/en unknown
- 1998-08-17 DE DE69837684T patent/DE69837684T2/de not_active Expired - Lifetime
- 1998-08-17 DK DK01203288T patent/DK1170293T3/da active
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- 1998-08-17 CA CA002268662A patent/CA2268662A1/fr not_active Abandoned
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- 1998-08-17 PT PT98942080T patent/PT956284E/pt unknown
- 1998-08-17 EP EP01203287A patent/EP1170292B1/fr not_active Expired - Lifetime
- 1998-08-17 EP EP01203288A patent/EP1170293B1/fr not_active Expired - Lifetime
- 1998-08-17 EP EP05108674A patent/EP1671960A2/fr not_active Withdrawn
- 1998-08-17 CN CNB2005100641228A patent/CN100351246C/zh not_active Expired - Fee Related
- 1998-08-17 PT PT01203287T patent/PT1170292E/pt unknown
- 1998-08-17 EP EP01203286A patent/EP1193262A1/fr not_active Withdrawn
- 1998-08-17 CN CNA2006101492418A patent/CN1974563A/zh active Pending
- 1998-08-17 PL PL377991A patent/PL201641B1/pl not_active IP Right Cessation
- 1998-08-17 RU RU99110384/04A patent/RU2225402C2/ru not_active IP Right Cessation
- 1998-08-17 DE DE69834584T patent/DE69834584T2/de not_active Expired - Fee Related
- 1998-08-17 AT AT01203288T patent/ATE326455T1/de not_active IP Right Cessation
- 1998-08-17 ES ES01203288T patent/ES2259646T3/es not_active Expired - Lifetime
- 1998-08-17 DE DE69836072T patent/DE69836072T2/de not_active Expired - Lifetime
- 1998-08-17 PT PT01203288T patent/PT1170293E/pt unknown
- 1998-08-17 ES ES01203287T patent/ES2286073T3/es not_active Expired - Lifetime
- 1998-08-17 AT AT01203287T patent/ATE360624T1/de not_active IP Right Cessation
- 1998-08-17 ID IDW990217A patent/ID21654A/id unknown
- 1998-08-17 HU HU0300425A patent/HUP0300425A3/hu unknown
- 1998-08-17 DK DK98942080T patent/DK0956284T3/da active
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- 1998-08-17 CA CA002597799A patent/CA2597799A1/fr not_active Abandoned
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- 1998-08-17 EP EP98942080A patent/EP0956284B1/fr not_active Expired - Lifetime
- 1998-08-17 EP EP07104179A patent/EP1795528A1/fr not_active Withdrawn
- 1998-08-17 DK DK01203287T patent/DK1170292T3/da active
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1999
- 1999-04-16 NO NO19991838A patent/NO325139B1/no not_active IP Right Cessation
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2000
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2005
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