BR9806145A - Processo para derivatização seletiva de taxanos - Google Patents
Processo para derivatização seletiva de taxanosInfo
- Publication number
- BR9806145A BR9806145A BR9806145-3A BR9806145A BR9806145A BR 9806145 A BR9806145 A BR 9806145A BR 9806145 A BR9806145 A BR 9806145A BR 9806145 A BR9806145 A BR 9806145A
- Authority
- BR
- Brazil
- Prior art keywords
- taxanes
- selective derivatization
- dab
- hydroxyl group
- derivatized
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 4
- 238000001212 derivatisation Methods 0.000 title abstract 3
- 229940123237 Taxane Drugs 0.000 title abstract 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 3
- YWLXLRUDGLRYDR-UHFFFAOYSA-N 10-deacetylbaccatin Chemical compound CC(=O)OC12COC1CC(O)C(C(C(O)C1=C(C)C(O)CC3(O)C1(C)C)=O)(C)C2C3OC(=O)C1=CC=CC=C1 YWLXLRUDGLRYDR-UHFFFAOYSA-N 0.000 abstract 2
- 229930012538 Paclitaxel Natural products 0.000 abstract 1
- 229960001592 paclitaxel Drugs 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- RCINICONZNJXQF-MZXODVADSA-N taxol Chemical compound O([C@@H]1[C@@]2(C[C@@H](C(C)=C(C2(C)C)[C@H](C([C@]2(C)[C@@H](O)C[C@H]3OC[C@]3([C@H]21)OC(C)=O)=O)OC(=O)C)OC(=O)[C@H](O)[C@@H](NC(=O)C=1C=CC=CC=1)C=1C=CC=CC=1)O)C(=O)C1=CC=CC=C1 RCINICONZNJXQF-MZXODVADSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
- C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
- C07F7/1872—Preparation; Treatments not provided for in C07F7/20
- C07F7/1892—Preparation; Treatments not provided for in C07F7/20 by reactions not provided for in C07F7/1876 - C07F7/1888
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epoxy Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Saccharide Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Plural Heterocyclic Compounds (AREA)
- Fats And Perfumes (AREA)
- Percussion Or Vibration Massage (AREA)
- Soil Working Implements (AREA)
Abstract
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US5600097P | 1997-08-18 | 1997-08-18 | |
US8126598P | 1998-04-09 | 1998-04-09 | |
US09/063,477 US7288665B1 (en) | 1997-08-18 | 1998-04-20 | Process for selective derivatization of taxanes |
PCT/US1998/017016 WO1999009021A1 (en) | 1997-08-18 | 1998-08-17 | Process for selective derivatization of taxanes |
Publications (1)
Publication Number | Publication Date |
---|---|
BR9806145A true BR9806145A (pt) | 2000-01-18 |
Family
ID=27368950
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR9806145-3A BR9806145A (pt) | 1997-08-18 | 1998-08-17 | Processo para derivatização seletiva de taxanos |
Country Status (25)
Country | Link |
---|---|
US (5) | US7288665B1 (pt) |
EP (6) | EP1170292B1 (pt) |
JP (1) | JP2001504864A (pt) |
KR (1) | KR100596989B1 (pt) |
CN (3) | CN1974563A (pt) |
AT (3) | ATE326455T1 (pt) |
AU (1) | AU744987B2 (pt) |
BR (1) | BR9806145A (pt) |
CA (2) | CA2597799A1 (pt) |
CY (1) | CY1105399T1 (pt) |
CZ (1) | CZ296580B6 (pt) |
DE (3) | DE69837684T2 (pt) |
DK (3) | DK1170293T3 (pt) |
ES (3) | ES2259646T3 (pt) |
HU (1) | HUP0300425A3 (pt) |
ID (1) | ID21654A (pt) |
IL (3) | IL129386A0 (pt) |
NO (4) | NO325139B1 (pt) |
NZ (1) | NZ335156A (pt) |
PL (3) | PL193674B1 (pt) |
PT (3) | PT956284E (pt) |
RU (1) | RU2225402C2 (pt) |
SG (1) | SG97986A1 (pt) |
WO (1) | WO1999009021A1 (pt) |
ZA (1) | ZA987394B (pt) |
Families Citing this family (74)
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1998
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