DK3300745T3 - Kimærisk antigenreceptor og fremgangsmåder til anvendelse deraf - Google Patents

Kimærisk antigenreceptor og fremgangsmåder til anvendelse deraf Download PDF

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Publication number
DK3300745T3
DK3300745T3 DK17187293T DK17187293T DK3300745T3 DK 3300745 T3 DK3300745 T3 DK 3300745T3 DK 17187293 T DK17187293 T DK 17187293T DK 17187293 T DK17187293 T DK 17187293T DK 3300745 T3 DK3300745 T3 DK 3300745T3
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methods
antigen receptor
chemical antigen
chemical
receptor
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DK17187293T
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English (en)
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Chia-Yung Wu
James Onuffer
Wendell A Lim
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Univ California
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K39/46
    • A61K2239/10—Indexing codes associated with cellular immunotherapy of group A61K39/46 characterized by the structure of the chimeric antigen receptor [CAR]
    • A61K2239/23—On/off switch
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K39/46
    • A61K2239/10—Indexing codes associated with cellular immunotherapy of group A61K39/46 characterized by the structure of the chimeric antigen receptor [CAR]
    • A61K2239/23—On/off switch
    • A61K2239/24—Dimerizable CARs; CARs with adapter
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K39/46
    • A61K2239/31—Indexing codes associated with cellular immunotherapy of group A61K39/46 characterized by the route of administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K39/46
    • A61K2239/38—Indexing codes associated with cellular immunotherapy of group A61K39/46 characterised by the dose, timing or administration schedule
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    • A61K39/46—Cellular immunotherapy
    • A61K39/461—Cellular immunotherapy characterised by the cell type used
    • A61K39/4611—T-cells, e.g. tumor infiltrating lymphocytes [TIL], lymphokine-activated killer cells [LAK] or regulatory T cells [Treg]
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    • A61K39/463—Cellular immunotherapy characterised by recombinant expression
    • A61K39/4631—Chimeric Antigen Receptors [CAR]
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    • A61K39/4643—Vertebrate antigens
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    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
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    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70575—NGF/TNF-superfamily, e.g. CD70, CD95L, CD153, CD154
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    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70578—NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
    • C—CHEMISTRY; METALLURGY
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    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
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    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
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    • C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
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    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2878—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
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    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
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DK17187293T 2013-02-15 2014-02-14 Kimærisk antigenreceptor og fremgangsmåder til anvendelse deraf DK3300745T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361765585P 2013-02-15 2013-02-15
EP14751227.1A EP2956175B1 (en) 2013-02-15 2014-02-14 Chimeric antigen receptor and methods of use thereof

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DK3300745T3 true DK3300745T3 (da) 2019-11-04

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DK14751227.1T DK2956175T3 (da) 2013-02-15 2014-02-14 Kimærisk antigenreceptor og fremgangsmåder til anvendelse deraf
DK17187293T DK3300745T3 (da) 2013-02-15 2014-02-14 Kimærisk antigenreceptor og fremgangsmåder til anvendelse deraf

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US (9) US20150368342A1 (da)
EP (5) EP3881868B1 (da)
JP (5) JP6450690B2 (da)
KR (5) KR20210147101A (da)
CN (2) CN110423282B (da)
AU (5) AU2014216130B2 (da)
CA (1) CA2901115A1 (da)
CY (1) CY1122386T1 (da)
DK (2) DK2956175T3 (da)
ES (3) ES2653487T3 (da)
HK (2) HK1218625A1 (da)
HR (1) HRP20192123T1 (da)
HU (2) HUE036250T2 (da)
IL (3) IL272279B2 (da)
LT (2) LT3300745T (da)
MX (2) MX369545B (da)
NO (1) NO2929995T3 (da)
PL (3) PL3300745T3 (da)
PT (3) PT3300745T (da)
SI (2) SI3613439T1 (da)
WO (1) WO2014127261A1 (da)

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DK2956175T3 (da) 2013-02-15 2017-11-27 Univ California Kimærisk antigenreceptor og fremgangsmåder til anvendelse deraf
JP6541639B2 (ja) 2013-03-14 2019-07-10 ベリカム ファーマシューティカルズ， インコーポレイテッド Ｔ細胞増殖をコントロールするための方法
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