MX369545B - Receptor de antígeno químerico y métodos para usarlo. - Google Patents

Receptor de antígeno químerico y métodos para usarlo.

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Publication number
MX369545B
MX369545B MX2015010522A MX2015010522A MX369545B MX 369545 B MX369545 B MX 369545B MX 2015010522 A MX2015010522 A MX 2015010522A MX 2015010522 A MX2015010522 A MX 2015010522A MX 369545 B MX369545 B MX 369545B
Authority
MX
Mexico
Prior art keywords
car
antigen receptor
chimeric antigen
methods
present disclosure
Prior art date
Application number
MX2015010522A
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English (en)
Other versions
MX2015010522A (es
Inventor
Onuffer James
A Lim Wendell
Wu Chia-Yung
Original Assignee
Univ California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ California filed Critical Univ California
Publication of MX2015010522A publication Critical patent/MX2015010522A/es
Publication of MX369545B publication Critical patent/MX369545B/es

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    • A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K39/46
    • A61K2239/10—Indexing codes associated with cellular immunotherapy of group A61K39/46 characterized by the structure of the chimeric antigen receptor [CAR]
    • A61K2239/23—On/off switch
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    • A61K2239/10—Indexing codes associated with cellular immunotherapy of group A61K39/46 characterized by the structure of the chimeric antigen receptor [CAR]
    • A61K2239/23—On/off switch
    • A61K2239/24—Dimerizable CARs; CARs with adapter
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    • A61K2239/31—Indexing codes associated with cellular immunotherapy of group A61K39/46 characterized by the route of administration
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    • A61K39/4631—Chimeric Antigen Receptors [CAR]
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    • C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
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    • C07K16/2878—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
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Abstract

La presente invención se refiere a un receptor de antígeno quimérico (CAR) condicionalmente activo y heterodimérico, y un ácido nucleico que comprende una secuencia de nucleótidos que codifica el CAR. La presente descripción proporciona células genéticamente modificadas para producir el CAR. Un CAR de la presente descripción se puede utilizar en varios métodos, que también se proporcionan.
MX2015010522A 2013-02-15 2014-02-14 Receptor de antígeno químerico y métodos para usarlo. MX369545B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361765585P 2013-02-15 2013-02-15
PCT/US2014/016527 WO2014127261A1 (en) 2013-02-15 2014-02-14 Chimeric antigen receptor and methods of use thereof

Publications (2)

Publication Number Publication Date
MX2015010522A MX2015010522A (es) 2016-06-23
MX369545B true MX369545B (es) 2019-11-12

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MX2015010522A MX369545B (es) 2013-02-15 2014-02-14 Receptor de antígeno químerico y métodos para usarlo.
MX2019013498A MX2019013498A (es) 2013-02-15 2015-08-14 Receptor de antigeno quimerico y metodos para usarlo.

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MX2019013498A MX2019013498A (es) 2013-02-15 2015-08-14 Receptor de antigeno quimerico y metodos para usarlo.

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US (9) US20150368342A1 (es)
EP (5) EP3300745B9 (es)
JP (5) JP6450690B2 (es)
KR (5) KR20230022452A (es)
CN (2) CN110423282B (es)
AU (5) AU2014216130B2 (es)
CA (1) CA2901115A1 (es)
CY (1) CY1122386T1 (es)
DK (2) DK3300745T3 (es)
ES (3) ES2758227T3 (es)
HK (2) HK1218625A1 (es)
HR (1) HRP20192123T1 (es)
HU (2) HUE047487T2 (es)
IL (3) IL305629A (es)
LT (2) LT3300745T (es)
MX (2) MX369545B (es)
NO (1) NO2929995T3 (es)
PL (3) PL3613439T3 (es)
PT (3) PT2956175T (es)
SI (2) SI3300745T1 (es)
WO (1) WO2014127261A1 (es)

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