IT1261489B - Procedimento per la produzione di r amminocarnitina e s amminocarnitina. - Google Patents

Procedimento per la produzione di r amminocarnitina e s amminocarnitina.

Info

Publication number
IT1261489B
IT1261489B ITRM930502A ITRM930502A IT1261489B IT 1261489 B IT1261489 B IT 1261489B IT RM930502 A ITRM930502 A IT RM930502A IT RM930502 A ITRM930502 A IT RM930502A IT 1261489 B IT1261489 B IT 1261489B
Authority
IT
Italy
Prior art keywords
amminocarnitina
procedure
production
azide
methanesulfonylcarnitine
Prior art date
Application number
ITRM930502A
Other languages
English (en)
Inventor
Maria Ornella Tinti
Original Assignee
Sigma Tau Ind Farmaceuti
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma Tau Ind Farmaceuti filed Critical Sigma Tau Ind Farmaceuti
Publication of ITRM930502A0 publication Critical patent/ITRM930502A0/it
Priority to ITRM930502A priority Critical patent/IT1261489B/it
Priority to EP94830354A priority patent/EP0636603B1/en
Priority to ES94830354T priority patent/ES2081230T3/es
Priority to DE69400032T priority patent/DE69400032T2/de
Priority to DK94830354.0T priority patent/DK0636603T3/da
Priority to AT94830354T priority patent/ATE130597T1/de
Priority to JP17075294A priority patent/JP3550423B2/ja
Priority to US08/317,658 priority patent/US5532409A/en
Publication of ITRM930502A1 publication Critical patent/ITRM930502A1/it
Priority to GR950402586T priority patent/GR3018197T3/el
Application granted granted Critical
Publication of IT1261489B publication Critical patent/IT1261489B/it
Priority to HK98104935A priority patent/HK1005860A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/30—Preparation of optical isomers
    • C07C227/32—Preparation of optical isomers by stereospecific synthesis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
    • C07C227/16—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions not involving the amino or carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/26—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having more than one amino group bound to the carbon skeleton, e.g. lysine

Abstract

Viene descritto un procedimento per la preparazione di amminocarnitina in cui la metansolfonilcarnitina viene convertita in lattone che per trattamento con una azide si trasforma in azido carnitina che per idrogenazione catalitica fornisce il composto desiderato.
ITRM930502A 1993-07-29 1993-07-29 Procedimento per la produzione di r amminocarnitina e s amminocarnitina. IT1261489B (it)

Priority Applications (10)

Application Number Priority Date Filing Date Title
ITRM930502A IT1261489B (it) 1993-07-29 1993-07-29 Procedimento per la produzione di r amminocarnitina e s amminocarnitina.
DK94830354.0T DK0636603T3 (da) 1993-07-29 1994-07-13 Fremgangsmåde til fremstilling af R-aminocarnitin og S-aminocarnitin
ES94830354T ES2081230T3 (es) 1993-07-29 1994-07-13 Procedimiento para producir r-aminocarnitina y s-aminocarnitina.
DE69400032T DE69400032T2 (de) 1993-07-29 1994-07-13 Verfahren zur Herstellung von R-Aminocarnitin und S-Aminocarnitin.
EP94830354A EP0636603B1 (en) 1993-07-29 1994-07-13 Process for producing R-aminicarnitine and S-aminocarnitine
AT94830354T ATE130597T1 (de) 1993-07-29 1994-07-13 Verfahren zur herstellung von r-aminocarnitin und s-aminocarnitin.
JP17075294A JP3550423B2 (ja) 1993-07-29 1994-07-22 Ｒ−およびｓ−アミノカルニチンの製造法
US08/317,658 US5532409A (en) 1993-07-29 1994-09-30 Process for producing R-aminocarnitine and S-aminocarnitine
GR950402586T GR3018197T3 (en) 1993-07-29 1995-11-23 Process for producing R-aminicarnitine and S-aminocarnitine.
HK98104935A HK1005860A1 (en) 1993-07-29 1998-06-05 Process for producing r-aminicarnitine and s-aminocarnitine

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITRM930502A IT1261489B (it) 1993-07-29 1993-07-29 Procedimento per la produzione di r amminocarnitina e s amminocarnitina.

Publications (3)

Publication Number Publication Date
ITRM930502A0 ITRM930502A0 (it) 1993-07-29
ITRM930502A1 ITRM930502A1 (it) 1995-01-29
IT1261489B true IT1261489B (it) 1996-05-23

Family

ID=11401885

Family Applications (1)

Application Number Title Priority Date Filing Date
ITRM930502A IT1261489B (it) 1993-07-29 1993-07-29 Procedimento per la produzione di r amminocarnitina e s amminocarnitina.

Country Status (10)

Country Link
US (1) US5532409A (it)
EP (1) EP0636603B1 (it)
JP (1) JP3550423B2 (it)
AT (1) ATE130597T1 (it)
DE (1) DE69400032T2 (it)
DK (1) DK0636603T3 (it)
ES (1) ES2081230T3 (it)
GR (1) GR3018197T3 (it)
HK (1) HK1005860A1 (it)
IT (1) IT1261489B (it)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1261828B (it) 1993-07-14 1996-06-03 Sigma Tau Ind Farmaceuti Esteri di acil l-carnitine e composizioni farmaceutiche che li contengono per il trattamento dello shock endotossico.
IT1276207B1 (it) * 1995-09-29 1997-10-27 Sigma Tau Ind Farmaceuti Procedimento per la preparazione del (s)-b-idrossi-gamma- butirrolattone
IT1297120B1 (it) * 1997-12-16 1999-08-03 Sigma Tau Ind Farmaceuti Procedimento per la produzione di (r)-3-idrossi-4-butirrolattone utile nella preparazione della (r)-carnitina
IT1299182B1 (it) * 1998-05-29 2000-02-29 Sigma Tau Ind Farmaceuti Procedimento chimico per la sintesi stereoselettiva della r-(-)- carnitina.
IT1306162B1 (it) 1999-06-30 2001-05-30 Sigma Tau Ind Farmaceuti Sintesi di (r) e (s)-amminocarnitina e di suoi derivati a partire daacido d e l-aspartico.
US6822115B2 (en) 1999-06-30 2004-11-23 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Synthesis of (R) and (S)-aminocarnitine, (R) and (S)-4-phosphonium-3-amino-butanoate, (R) and (S) 3,4-diaminobutanoic acid, and their derivatives starting from D- and L-aspartic acid
IT1306184B1 (it) 1999-08-05 2001-05-30 Sigma Tau Ind Farmaceuti Nitrilossi derivati della (r) e (s)-carnitina.
ITRM20010456A1 (it) * 2001-07-26 2003-01-27 Sigma Tau Ind Farmaceuti Procedimento per la preparazione di (r)- o (s)- amminocarnitina sale interno, dei suoi sali e dei suoi derivati.
US7776915B2 (en) * 2005-03-24 2010-08-17 Tracie Martyn International, Llc Topical formulations and methods of use

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3105082A (en) * 1960-12-02 1963-09-24 Dow Chemical Co Synthesis of amino acids
US4521432A (en) * 1981-11-26 1985-06-04 Takeda Chemical Industries, Ltd. Physiologically active substance FA-5859, its derivative, their production and use
EP0127098B1 (en) * 1983-05-25 1989-02-08 Takeda Chemical Industries, Ltd. Derivatives of beta-amino-gamma-trimethylammonio-butyrate, their production and use
IT1205758B (it) * 1987-03-18 1989-03-31 Sigma Tau Ind Farmaceuti Procedimento per la produzione di (-) n-acetil ammino carnitina e di (+) n-acetil ammino carnitina
IT1231751B (it) * 1989-04-12 1991-12-21 Sigma Tau Ind Farmaceuti Procedimento per la produzione di r(+) amminocarnitina e s(-) amminocarnitina

Also Published As

Publication number Publication date
GR3018197T3 (en) 1996-02-29
ES2081230T3 (es) 1996-02-16
HK1005860A1 (en) 1999-01-29
DE69400032D1 (de) 1996-01-04
ITRM930502A1 (it) 1995-01-29
DE69400032T2 (de) 1996-04-18
JP3550423B2 (ja) 2004-08-04
EP0636603B1 (en) 1995-11-22
JPH0770017A (ja) 1995-03-14
ATE130597T1 (de) 1995-12-15
EP0636603A1 (en) 1995-02-01
DK0636603T3 (da) 1995-12-18
ITRM930502A0 (it) 1993-07-29
US5532409A (en) 1996-07-02

Similar Documents

Publication Publication Date Title
IL184320A0 (en) Process for selective derivatization of taxanes
EP1589017A3 (en) 12,13-modified epothilone derivatives
CA2164685A1 (en) Method for producing an alcohol
ATE234092T1 (de) 2-alkylpyrrolidine
EP0701112A3 (en) Method for manufacturing a ceramic membrane structure having a convex part and membrane structure obtained by this method
IT1261489B (it) Procedimento per la produzione di r amminocarnitina e s amminocarnitina.
PH31685A (en) Method of producing l-glutamic acid by fermentation.
IT1250692B (it) Procedimento per la preparazione di demetilepipodofillotossina- beta-d-glucosidi.
ES2112433T3 (es) Sintesis de derivados del acido n-acetil neuraminico.
PT92726A (pt) Processo de eliminacao de etanol de bebidas produzidas por fermentacao
AU3345599A (en) A process for preparing chiral (s)-2,3-disubstituted-1-propylamine derivatives
PT633928E (pt) Microrganismos processo de preparacao e utilizacao
BR9606916A (pt) Processo de fabricação do palatinitol
ATE126794T1 (de) Verfahren zur herstellung von formyltetrahydropyranen.
PT1032580E (pt) Processo para a n-desmetilacao de eritromicinas e seus derivados
DE69529514T2 (de) Verfahren zur herstellung von (r)-2-amino-1-phenylethanol oder seinen halogenierten derivaten, verfahren zur herstellung von optisch aktivem phenylserin und seinen halogenierten derivaten, und die neuartige verbindung 3-(3-chlorophenyl)serin
DE69420586D1 (de) Verfahren zur herstellung eines zeoliths
BG102535A (en) Dihydrate of (2r,3s)-3-tert-butoxycarbonylamino-2-hydroxy-3-phenylpropionate of 4,10 beta-diacetoxy-2 alpha-benzoyloxy-5 beta, 20-epoxy-1-hydroxy-9-oxo-19-nor-cyclopropa[g]tax-11-ene 13-alpha -yl and method for its preparaton
ES2166881T3 (es) Sintesis de la (+)-pancratistatina.
MX9405030A (es) Procedimiento para la obtencion de n,n'-dibencilbispidina.
ES2128698T3 (es) Procedimiento para la obtencion de 8-alfa,12-oxido-13,14,15,16-tetranorlabdano.
ES2101653A1 (es) (+)-6-(5-cloropirid-2-il)-7-oxo-vinilocarboniloxi-5,6-dihidro pirrolo(3,4b)pirazina y su uso para un procedimiento de preparacion de (+)-6-(cloropirid-2-il)-5-(4-metilpiperazin-1-il)-carboniloxi-7-oxo-5,6-dihidropirrolo(3,4)pirazina.
MX9604879A (es) Metodos para la sintesis de retinoides 9-cis y sus intermediarios novedosos.
EP0352817A3 (en) Monoclonal antibody to catecholamine metabolite and quantitative assay for catecholamine metabolite
FR2738576B1 (fr) Anticorps specifiques de la 5 alpha reductase, kit de diagnostic, et procede de production des anticorps

Legal Events

Date Code Title Description
0001 Granted