US20080253911A1 - Pumping Cassette - Google Patents

Pumping Cassette Download PDF

Info

Publication number
US20080253911A1
US20080253911A1 US11/871,787 US87178707A US2008253911A1 US 20080253911 A1 US20080253911 A1 US 20080253911A1 US 87178707 A US87178707 A US 87178707A US 2008253911 A1 US2008253911 A1 US 2008253911A1
Authority
US
United States
Prior art keywords
fluid
cassette
membrane
pump
housing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
US11/871,787
Other languages
English (en)
Inventor
Jason A. Demers
Michael J. Wilt
Kevin L. Grant
James D. Dale
Brian Tracey
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Deka Products LP
Original Assignee
Deka Products LP
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Deka Products LP filed Critical Deka Products LP
Priority to US11/871,787 priority Critical patent/US20080253911A1/en
Assigned to DEKA PRODUCTS LIMITED PARTNERSHIP reassignment DEKA PRODUCTS LIMITED PARTNERSHIP ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: DALE, JAMES D., TRACEY, BRIAN, WILT, MICHAEL J., DEMERS, JASON A., GRANT, KEVIN L.
Priority to US12/199,196 priority patent/US8425471B2/en
Priority to US12/199,055 priority patent/US8393690B2/en
Priority to US12/199,166 priority patent/US20090107335A1/en
Priority to US12/199,077 priority patent/US9028691B2/en
Priority to US12/199,068 priority patent/US8562834B2/en
Priority to CA3075012A priority patent/CA3075012C/en
Priority to EP17159187.8A priority patent/EP3228337B1/en
Priority to EP08838971.3A priority patent/EP2197513B1/en
Priority to KR1020147023314A priority patent/KR101934142B1/ko
Priority to KR1020107010384A priority patent/KR101573948B1/ko
Priority to EP16152813.8A priority patent/EP3037117B1/en
Priority to KR1020197035516A priority patent/KR102196471B1/ko
Priority to CA3177048A priority patent/CA3177048A1/en
Priority to JP2010528896A priority patent/JP5324587B2/ja
Priority to CN200880121285.7A priority patent/CN101986776B/zh
Priority to MX2010003880A priority patent/MX340356B/es
Priority to EP11150584.8A priority patent/EP2319551B1/en
Priority to KR1020187037352A priority patent/KR101973034B1/ko
Priority to KR1020177002616A priority patent/KR101769521B1/ko
Priority to KR1020217043402A priority patent/KR102413969B1/ko
Priority to KR1020157011558A priority patent/KR101657569B1/ko
Priority to CA2702385A priority patent/CA2702385C/en
Priority to KR1020187006667A priority patent/KR101881911B1/ko
Priority to BR122019005896A priority patent/BR122019005896B8/pt
Priority to CA2971041A priority patent/CA2971041C/en
Priority to EP21158380.2A priority patent/EP3848067A1/en
Priority to KR1020177022556A priority patent/KR101838530B1/ko
Priority to KR1020167024526A priority patent/KR101702643B1/ko
Priority to CA2971046A priority patent/CA2971046C/en
Priority to KR1020147009763A priority patent/KR101574748B1/ko
Priority to CN201510086488.9A priority patent/CN104689393B/zh
Priority to CA2971044A priority patent/CA2971044C/en
Priority to CA3075014A priority patent/CA3075014C/en
Priority to KR1020167027838A priority patent/KR101780620B1/ko
Priority to PCT/US2008/011663 priority patent/WO2009051669A1/en
Priority to KR1020197011369A priority patent/KR102052692B1/ko
Priority to EP19155956.6A priority patent/EP3508231B1/en
Priority to KR1020217043220A priority patent/KR20220003166A/ko
Priority to AU2008312005A priority patent/AU2008312005B2/en
Priority to KR1020207036973A priority patent/KR20210000735A/ko
Priority to BRPI0818056A priority patent/BRPI0818056B8/pt
Priority to KR1020187020812A priority patent/KR101921878B1/ko
Publication of US20080253911A1 publication Critical patent/US20080253911A1/en
Priority to JP2011243747A priority patent/JP5270745B2/ja
Priority to US13/352,250 priority patent/US9649418B2/en
Priority to US13/619,266 priority patent/US8992075B2/en
Priority to US13/790,974 priority patent/US9539379B2/en
Priority to JP2013149599A priority patent/JP5749767B2/ja
Priority to US14/059,806 priority patent/US10441697B2/en
Priority to US14/132,838 priority patent/US9597442B2/en
Priority to US14/672,764 priority patent/US9535021B2/en
Priority to US14/692,801 priority patent/US9987407B2/en
Priority to JP2015099430A priority patent/JP5782207B2/ja
Priority to JP2015142465A priority patent/JP5824183B2/ja
Priority to JP2015200155A priority patent/JP6027206B2/ja
Priority to JP2016201759A priority patent/JP6389219B2/ja
Priority to US15/399,895 priority patent/US9795728B2/en
Priority to US15/463,888 priority patent/US10098998B2/en
Priority to US15/789,916 priority patent/US10780210B2/en
Priority to US15/996,247 priority patent/US10500327B2/en
Priority to JP2018153084A priority patent/JP6703054B2/ja
Priority to US16/594,181 priority patent/US11311656B2/en
Priority to US16/707,839 priority patent/US11110212B2/en
Priority to JP2020081788A priority patent/JP6955607B2/ja
Priority to US17/466,806 priority patent/US11752244B2/en
Priority to JP2021162808A priority patent/JP7410104B2/ja
Priority to US17/718,533 priority patent/US20220241479A1/en
Priority to US18/358,840 priority patent/US20230364312A1/en
Priority to JP2023215656A priority patent/JP2024023777A/ja
Abandoned legal-status Critical Current

Links

Images

Classifications

    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B43/00—Machines, pumps, or pumping installations having flexible working members
    • F04B43/02—Machines, pumps, or pumping installations having flexible working members having plate-like flexible members, e.g. diaphragms
    • F04B43/025—Machines, pumps, or pumping installations having flexible working members having plate-like flexible members, e.g. diaphragms two or more plate-like pumping members in parallel
    • F04B43/026—Machines, pumps, or pumping installations having flexible working members having plate-like flexible members, e.g. diaphragms two or more plate-like pumping members in parallel each plate-like pumping flexible member working in its own pumping chamber
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/15—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with a cassette forming partially or totally the flow circuit for the treating fluid, e.g. the dialysate fluid circuit or the treating gas circuit
    • A61M1/154—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with a cassette forming partially or totally the flow circuit for the treating fluid, e.g. the dialysate fluid circuit or the treating gas circuit with sensing means or components thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/15—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with a cassette forming partially or totally the flow circuit for the treating fluid, e.g. the dialysate fluid circuit or the treating gas circuit
    • A61M1/155—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with a cassette forming partially or totally the flow circuit for the treating fluid, e.g. the dialysate fluid circuit or the treating gas circuit with treatment-fluid pumping means or components thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/15—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with a cassette forming partially or totally the flow circuit for the treating fluid, e.g. the dialysate fluid circuit or the treating gas circuit
    • A61M1/156—Constructional details of the cassette, e.g. specific details on material or shape
    • A61M1/1561—Constructional details of the cassette, e.g. specific details on material or shape at least one cassette surface or portion thereof being flexible, e.g. the cassette having a rigid base portion with preformed channels and being covered with a foil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/15—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with a cassette forming partially or totally the flow circuit for the treating fluid, e.g. the dialysate fluid circuit or the treating gas circuit
    • A61M1/156—Constructional details of the cassette, e.g. specific details on material or shape
    • A61M1/1562—Details of incorporated reservoirs
    • A61M1/15625—Details of incorporated reservoirs the reservoirs acting as balance chambers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/15—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with a cassette forming partially or totally the flow circuit for the treating fluid, e.g. the dialysate fluid circuit or the treating gas circuit
    • A61M1/156—Constructional details of the cassette, e.g. specific details on material or shape
    • A61M1/1565—Details of valves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1601—Control or regulation
    • A61M1/1603—Regulation parameters
    • A61M1/1605—Physical characteristics of the dialysate fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1621—Constructional aspects thereof
    • A61M1/1635—Constructional aspects thereof with volume chamber balancing devices between used and fresh dialysis fluid
    • A61M1/1639—Constructional aspects thereof with volume chamber balancing devices between used and fresh dialysis fluid linked by membranes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1654—Dialysates therefor
    • A61M1/1656—Apparatus for preparing dialysates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1654—Dialysates therefor
    • A61M1/1656—Apparatus for preparing dialysates
    • A61M1/166—Heating
    • A61M1/1664—Heating with temperature control
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1654—Dialysates therefor
    • A61M1/1656—Apparatus for preparing dialysates
    • A61M1/1666—Apparatus for preparing dialysates by dissolving solids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/28—Peritoneal dialysis ; Other peritoneal treatment, e.g. oxygenation
    • A61M1/287—Dialysates therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/10—Location thereof with respect to the patient's body
    • A61M60/104—Extracorporeal pumps, i.e. the blood being pumped outside the patient's body
    • A61M60/109—Extracorporeal pumps, i.e. the blood being pumped outside the patient's body incorporated within extracorporeal blood circuits or systems
    • A61M60/113—Extracorporeal pumps, i.e. the blood being pumped outside the patient's body incorporated within extracorporeal blood circuits or systems in other functional devices, e.g. dialysers or heart-lung machines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/20—Type thereof
    • A61M60/247—Positive displacement blood pumps
    • A61M60/253—Positive displacement blood pumps including a displacement member directly acting on the blood
    • A61M60/268—Positive displacement blood pumps including a displacement member directly acting on the blood the displacement member being flexible, e.g. membranes, diaphragms or bladders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/30—Medical purposes thereof other than the enhancement of the cardiac output
    • A61M60/36—Medical purposes thereof other than the enhancement of the cardiac output for specific blood treatment; for specific therapy
    • A61M60/37—Haemodialysis, haemofiltration or diafiltration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/40—Details relating to driving
    • A61M60/424—Details relating to driving for positive displacement blood pumps
    • A61M60/427—Details relating to driving for positive displacement blood pumps the force acting on the blood contacting member being hydraulic or pneumatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/80—Constructional details other than related to driving
    • A61M60/835—Constructional details other than related to driving of positive displacement blood pumps
    • A61M60/837—Aspects of flexible displacement members, e.g. shapes or materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/80—Constructional details other than related to driving
    • A61M60/845—Constructional details other than related to driving of extracorporeal blood pumps
    • A61M60/847—Constructional details other than related to driving of extracorporeal blood pumps arranged in a cassette
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/80—Constructional details other than related to driving
    • A61M60/845—Constructional details other than related to driving of extracorporeal blood pumps
    • A61M60/849—Disposable parts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/80—Constructional details other than related to driving
    • A61M60/845—Constructional details other than related to driving of extracorporeal blood pumps
    • A61M60/851—Valves
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B13/00—Pumps specially modified to deliver fixed or variable measured quantities
    • F04B13/02—Pumps specially modified to deliver fixed or variable measured quantities of two or more fluids at the same time
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B23/00—Pumping installations or systems
    • F04B23/04—Combinations of two or more pumps
    • F04B23/06—Combinations of two or more pumps the pumps being all of reciprocating positive-displacement type
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B41/00—Pumping installations or systems specially adapted for elastic fluids
    • F04B41/06—Combinations of two or more pumps
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B43/00—Machines, pumps, or pumping installations having flexible working members
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B43/00—Machines, pumps, or pumping installations having flexible working members
    • F04B43/02—Machines, pumps, or pumping installations having flexible working members having plate-like flexible members, e.g. diaphragms
    • F04B43/06—Pumps having fluid drive
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B43/00—Machines, pumps, or pumping installations having flexible working members
    • F04B43/02—Machines, pumps, or pumping installations having flexible working members having plate-like flexible members, e.g. diaphragms
    • F04B43/06—Pumps having fluid drive
    • F04B43/073—Pumps having fluid drive the actuating fluid being controlled by at least one valve
    • F04B43/0733—Pumps having fluid drive the actuating fluid being controlled by at least one valve with fluid-actuated pump inlet or outlet valves; with two or more pumping chambers in series
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B43/00—Machines, pumps, or pumping installations having flexible working members
    • F04B43/02—Machines, pumps, or pumping installations having flexible working members having plate-like flexible members, e.g. diaphragms
    • F04B43/06—Pumps having fluid drive
    • F04B43/073—Pumps having fluid drive the actuating fluid being controlled by at least one valve
    • F04B43/0736—Pumps having fluid drive the actuating fluid being controlled by at least one valve with two or more pumping chambers in parallel
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B45/00—Pumps or pumping installations having flexible working members and specially adapted for elastic fluids
    • F04B45/02—Pumps or pumping installations having flexible working members and specially adapted for elastic fluids having bellows
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B45/00—Pumps or pumping installations having flexible working members and specially adapted for elastic fluids
    • F04B45/04—Pumps or pumping installations having flexible working members and specially adapted for elastic fluids having plate-like flexible members, e.g. diaphragms
    • F04B45/053—Pumps having fluid drive
    • F04B45/0536—Pumps having fluid drive the actuating fluid being controlled by one or more valves
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B49/00—Control, e.g. of pump delivery, or pump pressure of, or safety measures for, machines, pumps, or pumping installations, not otherwise provided for, or of interest apart from, groups F04B1/00 - F04B47/00
    • F04B49/02—Stopping, starting, unloading or idling control
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B49/00—Control, e.g. of pump delivery, or pump pressure of, or safety measures for, machines, pumps, or pumping installations, not otherwise provided for, or of interest apart from, groups F04B1/00 - F04B47/00
    • F04B49/22—Control, e.g. of pump delivery, or pump pressure of, or safety measures for, machines, pumps, or pumping installations, not otherwise provided for, or of interest apart from, groups F04B1/00 - F04B47/00 by means of valves
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B53/00—Component parts, details or accessories not provided for in, or of interest apart from, groups F04B1/00 - F04B23/00 or F04B39/00 - F04B47/00
    • F04B53/06—Venting
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B53/00—Component parts, details or accessories not provided for in, or of interest apart from, groups F04B1/00 - F04B23/00 or F04B39/00 - F04B47/00
    • F04B53/10—Valves; Arrangement of valves
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B53/00—Component parts, details or accessories not provided for in, or of interest apart from, groups F04B1/00 - F04B23/00 or F04B39/00 - F04B47/00
    • F04B53/16—Casings; Cylinders; Cylinder liners or heads; Fluid connections
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B7/00—Piston machines or pumps characterised by having positively-driven valving
    • F04B7/02—Piston machines or pumps characterised by having positively-driven valving the valving being fluid-actuated
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B9/00—Piston machines or pumps characterised by the driving or driven means to or from their working members
    • F04B9/08—Piston machines or pumps characterised by the driving or driven means to or from their working members the means being fluid
    • F04B9/10—Piston machines or pumps characterised by the driving or driven means to or from their working members the means being fluid the fluid being liquid
    • F04B9/109—Piston machines or pumps characterised by the driving or driven means to or from their working members the means being fluid the fluid being liquid having plural pumping chambers
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F17—STORING OR DISTRIBUTING GASES OR LIQUIDS
    • F17D—PIPE-LINE SYSTEMS; PIPE-LINES
    • F17D3/00—Arrangements for supervising or controlling working operations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/12—General characteristics of the apparatus with interchangeable cassettes forming partially or totally the fluid circuit
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/12—General characteristics of the apparatus with interchangeable cassettes forming partially or totally the fluid circuit
    • A61M2205/128—General characteristics of the apparatus with interchangeable cassettes forming partially or totally the fluid circuit with incorporated valves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/33—Controlling, regulating or measuring
    • A61M2205/3317—Electromagnetic, inductive or dielectric measuring means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/33—Controlling, regulating or measuring
    • A61M2205/3324—PH measuring means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/33—Controlling, regulating or measuring
    • A61M2205/3368—Temperature
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/40—Details relating to driving
    • A61M60/424—Details relating to driving for positive displacement blood pumps
    • A61M60/427—Details relating to driving for positive displacement blood pumps the force acting on the blood contacting member being hydraulic or pneumatic
    • A61M60/43—Details relating to driving for positive displacement blood pumps the force acting on the blood contacting member being hydraulic or pneumatic using vacuum at the blood pump, e.g. to accelerate filling
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/80—Constructional details other than related to driving
    • A61M60/855—Constructional details other than related to driving of implantable pumps or pumping devices
    • A61M60/89—Valves
    • A61M60/892—Active valves, i.e. actuated by an external force
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/80—Constructional details other than related to driving
    • A61M60/855—Constructional details other than related to driving of implantable pumps or pumping devices
    • A61M60/89—Valves
    • A61M60/894—Passive valves, i.e. valves actuated by the blood
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A90/00—Technologies having an indirect contribution to adaptation to climate change
    • Y02A90/10—Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T137/00—Fluid handling
    • Y10T137/0318—Processes
    • Y10T137/0324—With control of flow by a condition or characteristic of a fluid
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T137/00—Fluid handling
    • Y10T137/0318—Processes
    • Y10T137/0324—With control of flow by a condition or characteristic of a fluid
    • Y10T137/0379—By fluid pressure
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T137/00—Fluid handling
    • Y10T137/2496—Self-proportioning or correlating systems
    • Y10T137/2514—Self-proportioning flow systems
    • Y10T137/2521—Flow comparison or differential response
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T137/00—Fluid handling
    • Y10T137/8593—Systems
    • Y10T137/85978—With pump
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T137/00—Fluid handling
    • Y10T137/8593—Systems
    • Y10T137/85978—With pump
    • Y10T137/86131—Plural
    • Y10T137/86139—Serial

Definitions

  • the present invention relates to a pumping cassette for pumping fluid.
  • the cassette includes housing.
  • the housing includes at least one fluid inlet line and at least one fluid outlet line.
  • the cassette includes at least one reciprocating pressure displacement membrane pump within the housing. The pressure pump pumps at least one fluid from the fluid inlet line to at least one of the fluid outlet line.
  • the cassette includes at least one mixing chamber within the housing. The mixing chamber is fluidly connected to the fluid outlet line.
  • the reciprocating pressure displacement pump includes a curved rigid chamber wall and a flexible membrane attached to the rigid chamber wall.
  • the flexible membrane and the rigid chamber wall define a pumping chamber.
  • the cassette housing includes a top plate, a midplate and a bottom plate.
  • the cassette also includes at least one valve.
  • the at least one valve includes a valve housing having a membrane. The membrane divides the housing into two chambers.
  • the mixing chamber includes a curved rigid chamber wall having at least one fluid inlet and at least one fluid outlet.
  • the cassette also includes at least one metering membrane pump within the housing.
  • the metering pump fluidly connects to the mixing chamber on the housing and to a metering pump fluid line.
  • the metering pump fluid line is fluidly connected to the at least one of the at least one fluid inlet lines.
  • the cassette includes a housing including at least two fluid inlet lines and at least one fluid outlet line. Also included is at least one reciprocating pressure displacement membrane pump within the housing. The pressure pump pumps a fluid from at least one of the fluid inlet line to at lease one of the fluid outlet line.
  • the cassette also includes at least one mixing chamber within the housing, the mixing chamber fluidly connected to the fluid outlet line.
  • at least one metering membrane pump within the housing. The metering membrane pump fluidly connects to the mixing chamber on the housing and to a metering pump fluid line. The metering pump fluid line is fluidly connected to the at least one of the at least two fluid inlet lines.
  • the cassette include one or more of the following.
  • the reciprocating pressure displacement pump includes a curved rigid chamber wall and a flexible membrane attached to the rigid chamber wall.
  • the flexible membrane and the rigid chamber wall define a pumping chamber.
  • the cassette housing includes a top plate, a midplate and a bottom plate.
  • the mixing chamber includes a curved rigid chamber wall having at least one fluid inlet and at least one fluid outlet.
  • the cassette further includes at least one valve.
  • the valve includes a valve housing having a membrane dividing the housing into two chambers.
  • the pump cassette includes a housing.
  • the housing includes at least three fluid inlet lines and at least one fluid outlet line.
  • the cassette also includes at least two reciprocating pressure displacement membrane pumps within the housing that pump a fluid from at least one of the fluid inlet lines to at lease one of the fluid outlet line.
  • the cassette includes at least one mixing chamber within the housing that is fluidly connected to the fluid outlet line.
  • the cassette also includes at least two metering membrane pumps within the housing. The metering pumps are fluidly connected to respective fluid inlet lines and to the mixing chamber on the housing. The metering pumps pump a volume of a respective fluid from the fluid inlet lines to a fluid line fluidly connected to the mixing chamber.
  • the reciprocating pressure displacement pump includes a curved rigid chamber wall and a flexible membrane attached to the rigid chamber wall.
  • the flexible membrane and the rigid chamber wall define a pumping chamber.
  • the cassette housing includes a top plate, a midplate and a bottom plate.
  • the cassette includes at least one valve.
  • the valve includes a valve housing having a membrane, the membrane dividing the housing into two chambers.
  • FIG. 1A is a sectional view of one embodiment of a pod-pump that is incorporated into embodiments of cassette;
  • FIG. 1B is a sectional view of an exemplary embodiment of a pod pump that is incorporated into embodiments of the cassette;
  • FIG. 2A is an illustrative sectional view of one embodiment of one type of pneumatically controlled valve that is incorporated into some embodiments of the cassette;
  • FIG. 2B is a sectional view of another embodiment of one type of pneumatically controlled valve that is incorporated into some embodiments of the cassette;
  • FIG. 2C is a sectional view of another embodiment of one type of pneumatically controlled valve that is incorporated into some embodiments of the cassette;
  • FIG. 2D is a sectional view of another embodiment of one type of pneumatically controlled valve that is incorporated into some embodiments of the cassette;
  • FIGS. 2E-2F are top and bottom views of embodiments of the valving membrane
  • FIG. 2G shows pictorial, top and cross sectional views of one embodiment of the valving membrane
  • FIG. 3 is a sectional view of a pod pump within a cassette
  • FIG. 4 is a sectional view of a pod pump within a cassette having a variable membrane
  • FIGS. 4A and 4B are top and section views respectively of a pod pump within a cassette having a dimpled/variable membrane
  • FIGS. 4C and 4D are pictorial views of a single ring membrane with a variable surface
  • FIGS. 5A-5D are side views of various embodiments of variable membranes
  • FIGS. 5E-5H are pictorial views of various embodiments of the metering pump membrane
  • FIGS. 6A and 6B are pictorial views of a double ring membrane with a smooth surface
  • FIGS. 6C and 6D are pictorial views of a double ring membrane with a dimple surface
  • FIGS. 6E and 6F are pictorial views of double ring membranes with variable surfaces
  • FIG. 6G is a cross sectional view of a double ring membrane with a variable surface
  • FIG. 7 is a schematic showing a pressure actuation system that may be used to actuate a pod pump
  • FIG. 8 is one embodiment of the fluid flow-path schematic of the cassette
  • FIG. 9 is an alternate embodiment fluid flow-path schematic for an alternate embodiment of the cassette.
  • FIG. 10 is an isometric front view of the exemplary embodiment of the actuation side of the midplate of the cassette with the valves indicated corresponding to FIG. 8 ;
  • FIG. 11A are front and isometric views of the exemplary embodiment of the outer top plate of the cassette.
  • FIG. 11B are front and isometric views of the exemplary embodiment of the inner top plate of the cassette.
  • FIG. 11C is a side view of the exemplary embodiment of the top plate of the cassette.
  • FIG. 12A are front and isometric views of the exemplary embodiment of the fluid side of the midplate of the cassette
  • FIG. 12B are front and isometric views of the exemplary embodiment of the air side of the midplate of the cassette
  • FIG. 12C is a side view of the exemplary embodiment of the midplate of the cassette.
  • FIG. 13A are front and isometric views of the exemplary embodiment of the inner side of the bottom plate of the cassette
  • FIG. 13B are front and isometric views of the exemplary embodiment of the outer side of the bottom plate of the cassette.
  • FIG. 13C is a side view of the exemplary embodiment of the midplate of the cassette.
  • FIG. 14A is a top view of the assembled exemplary embodiment of the cassette
  • FIG. 14B is a bottom view of the assembled exemplary embodiment of the cassette
  • FIG. 14C is an exploded view of the assembled exemplary embodiment of the cassette
  • FIG. 14D is an exploded view of the assembled exemplary embodiment of the cassette
  • FIGS. 15A-15C show cross sectional views of the exemplary embodiment of the assembled cassette
  • FIG. 16A show isometric and top views of an alternate embodiment of the top plate according to an alternate embodiment of the cassette
  • FIG. 16B show bottom views of an alternate embodiment of the top plate according to an alternate embodiment of the cassette
  • FIG. 16C shows a side view of the alternate embodiment of the top plate
  • FIG. 17A show isometric and top views of an alternate embodiment of the midplate according to an alternate embodiment of the cassette
  • FIG. 17B show isometric and bottom views of an alternate embodiment of the midplate according to an alternate embodiment of the cassette
  • FIG. 17C shows a side view of the alternate embodiment of the midplate
  • FIG. 18A show isometric and top views of an alternate embodiment of the bottom plate according to an alternate embodiment of the cassette
  • FIG. 18B show isometric and bottom views of an alternate embodiment of the bottom according to an alternate embodiment of the cassette
  • FIG. 18C shows a side view of the alternate embodiment of the bottom plate
  • FIG. 19A is a top view of an assembled alternate embodiment of the cassette
  • FIG. 19B is an exploded view of the assembled alternate embodiment of the cassette.
  • FIG. 19C is an exploded view of the assembled alternate embodiment of the cassette.
  • FIGS. 20A-20B shows a cross sectional view of the exemplary embodiment of the assembled cassette.
  • the pumping cassette includes various features, namely, pod pumps, fluid lines and in some embodiment, valves.
  • the cassette embodiments shown and described in this description include exemplary and some alternate embodiments. However, any variety of cassettes having a similar functionality is contemplated.
  • the cassette embodiments described herein are implementations of the fluid schematics as shown in FIGS. 8A and 8B , in other embodiments, the cassette may have varying fluid paths and/or valve placement and/or pod pump placements and numbers and thus, is still within the scope of the invention.
  • the cassette includes a top plate, a midplate and a bottom plate.
  • the top plate includes pump chambers and fluid lines
  • the midplate includes complementary fluid lines
  • metering pumps and valves and the bottom plate includes actuation chambers (and in some embodiments, the top plate and the bottom plate include complementary portions of a balancing chamber).
  • the membranes are located between the midplate and the bottom plate, however, with respect to balancing chambers, a portion of a membrane is located between the midplate and the top plate.
  • Some embodiments include where the membrane is attached to the cassette, either overmolded, captured, bonded, press fit, welded in or any other process or method for attachment, however, in the exemplary embodiments, the membranes are separate from the top plate, midplate and bottom plate until the plates are assembled.
  • the cassettes may be constructed of a variety of materials. Generally, in the various embodiment, the materials used are solid and nan flexible. In the preferred embodiment, the plates are constructed of polysulfone, but in other embodiments, the cassettes are constructed of any other solid material and in exemplary embodiment, of any thermoplastic or thermoset.
  • the cassettes are formed by placing the membranes in their correct locations, assembling the plates in order and connecting the plates.
  • the plates are connected using a laser welding technique.
  • the plates may be glued, mechanically fastened, strapped together, ultrasonically welded or any other mode of attaching the plates together.
  • the cassette may be used to pump any type of fluid from any source to any location.
  • the types of fluid include nutritive, nonnutritive, inorganic chemicals, organic chemicals, bodily fluids or any other type of fluid.
  • fluid in some embodiments include a gas, thus, in some embodiments, the cassette is used to pump a gas.
  • the cassette serves to pump and direct the fluid from and to the desired locations.
  • outside pumps pump the fluid into the cassette and the cassette pumps the fluid out.
  • the pod pumps serve to pull the fluid into the cassette and pump the fluid out of the cassette.
  • valves being in different locations or additional valves are alternate embodiments of this cassette.
  • the fluid lines and paths shown in the figures described above are mere examples of fluid lines and paths. Other embodiments may have more, less and/or different fluid paths. In still other embodiments, valves are not present in the cassette.
  • the number of pod pumps described above may also vary depending on the embodiment.
  • the cassette includes one.
  • the cassette includes more than two pod pumps.
  • the pod pumps can be single pumps or work in tandem to provide a more continuous flow. Either or both may be used in various embodiments of the cassette.
  • the various fluid inlets and fluid outlets are fluid ports.
  • a fluid inlet can be a fluid outlet.
  • the designation of the fluid port as a fluid inlet or a fluid outlet is only for description purposes.
  • the various embodiments have interchangeable fluid ports.
  • the fluid ports are provided to impart particular fluid paths onto the cassette. These fluid ports are not necessarily all used all of the time; instead, the variety of fluid ports provides flexibility of use of the cassette in practice.
  • FIG. 1A is a sectional view of an exemplary pod pump 100 that is incorporated into a fluid control or pump cassette (see also FIGS. 3 and 4 ), in accordance with an exemplary embodiment of the cassette.
  • the pod pump is formed from three rigid pieces, namely a “top” plate 106 , a midplate 108 , and a “bottom” plate 110 (it should be noted that the terms “top” and “bottom” are relative and are used here for convenience with reference to the orientation shown in FIG. 1A ).
  • the top and bottom plates 106 and 110 include generally hemispheroid portions that when assembled together define a hemispheroid chamber, which is a pod pump 100 .
  • a membrane 112 separates the central cavity of the pod pump into two chambers.
  • these chambers are: the pumping chamber that receives the fluid to be pumped and an actuation chamber for receiving the control gas that pneumatically actuates the pump.
  • An inlet 102 allows fluid to enter the pumping chamber, and an outlet 104 allows fluid to exit the pumping chamber.
  • the inlet 102 and the outlet 104 may be formed between midplate 108 and the top plate 106 .
  • Pneumatic pressure is provided through a pneumatic port 114 to either force, with positive gas pressure, the membrane 112 against one wall of the pod pump cavity to minimize the pumping chamber's volume, or to draw, with negative gas pressure, the membrane 112 towards the other wail of the pod pump 100 cavity to maximize the pumping chamber's volume.
  • the membrane 112 is provided with a thickened rim 116 , which is held tightly by a protrusion 118 in the midplate 108 .
  • the membrane 112 can be placed in and held by the groove 108 before the bottom plate 110 is connected (in the exemplary embodiment) to the midplate 108 .
  • a groove is present on the chamber wall.
  • the groove acts to prevent folds in the membrane from trapping fluid in the chamber when emptying.
  • FIG. 1A a cross sectional view of a reciprocating positive-displacement pump 100 in a cassette is shown.
  • the pod pump 100 includes a flexible membrane 112 (also referred to as the “pump diaphragm” or “membrane”) mounted where the pumping chamber (also referred to as a “liquid chamber” or “liquid pumping chamber”) wall 122 and the actuation chamber (also referred to as the “pneumatic chamber”) wall 120 meet.
  • the pumping chamber also referred to as a “liquid chamber” or “liquid pumping chamber”
  • actuation chamber also referred to as the “pneumatic chamber”
  • the membrane 112 effectively divides that interior cavity into a variable-volume pumping chamber (defined by the rigid interior surface of the pumping chamber wall 122 and a surface of the membrane 112 ) and a complementary variable-volume actuation chamber (defined by the rigid interior surface of the actuation chamber wall 120 and a surface of the membrane 112 ).
  • the top portion 106 includes a fluid inlet 102 and a fluid outlet 104 , both of which are in fluid communication with the pumping/liquid chamber.
  • the bottom portion 110 includes an actuation or pneumatic interface 114 in fluid communication with the actuation chamber.
  • the membrane 112 can be urged to move back and forth within the cavity by alternately applying negative or vent to atmosphere and positive pneumatic pressure at the pneumatic interface 114 . As the membrane 112 reciprocates back and forth, the sum of the volumes of the pumping and actuation chambers remains constant.
  • the application of negative or vent to atmosphere pneumatic pressure to the actuation or pneumatic interface 114 tends to withdraw the membrane 112 toward the actuation chamber wall 120 so as to expand the pumping/liquid chamber and draw fluid into the pumping chamber through the inlet 102
  • the application of positive pneumatic pressure tends to push the membrane 112 toward the pumping chamber wall 122 so as to collapse the pumping chamber and expel fluid in the pumping chamber through the outlet 104
  • the interior surfaces of the pumping chamber wall 122 and the actuation chamber wall 120 limit movement of the membrane 112 as it reciprocates back and forth. In the embodiment shown in FIG.
  • the interior surfaces of the pumping chamber wall 122 and the actuation chamber wall 120 are rigid, smooth, and hemispherical.
  • an alternative rigid limit structure for example, a portion of a bezel used for providing pneumatic pressure and/or a set of ribs—may be used to limit the movement of the membrane as the pumping chamber approaches maximum value.
  • Bezels and rib structures are described generally in U.S. patent application Ser. No. 10/697,450 entitled BEZEL ASSEMBLY FOR PNEUMATIC CONTROL filed on Oct. 30, 2003 and published as Publication No. U.S. 2005/0095154 (Attorney Docket No. 1062/D75) and related PCT Application No.
  • the rigid limit structure such as the rigid actuation chamber wall 120 , a bezel, or a set of ribs—defines the shape of the membrane 112 when the pumping chamber is at its maximum value.
  • the membrane 112 (when urged against the rigid limit structure) and the rigid interior surface of the pumping chamber wall 122 define a spherical pumping chamber volume when the pumping chamber volume is at a minimum.
  • movement of the membrane 112 is limited by the pumping chamber wall 122 and the actuation chamber wall 120 .
  • the membrane 112 will move from a position limited by the actuation chamber wall 120 to a position limited by the pumping chamber wall 122 .
  • the membrane and the pumping chamber wall 122 define the maximum volume of the pumping chamber.
  • the pumping chamber is at its minimum volume.
  • the pumping chamber wall 122 and the actuation chamber wall 120 both have a hemispheroid shape so that the pumping chamber will have a spheroid shape when it is at its maximum volume.
  • a pumping chamber that attains a spheroid shape—and particularly a spherical shape—at maximum volume circulating flow may be attained throughout the pumping chamber.
  • Such shapes accordingly tend to avoid stagnant pockets of fluid in the pumping chamber.
  • the orientations of the inlet 102 and outlet 104 also tend to have an impact on the flow of fluid through the pumping chamber and in some embodiments, reduce the likelihood of stagnant pockets of fluid forming.
  • the spherical shape (and spheroid shapes in general) tends to create less shear and turbulence as the fluid circulates into, through, and out of the pumping chamber.
  • a raised flow path 30 is shown in the pumping chamber.
  • This raised flow path 30 allows for the fluid to continue flowing through the pod pumps after the membrane reaches the end of stroke.
  • the raised flow path 30 minimizes the chances of the membrane causing air or fluid to be trapped in the pod pump or the membrane blocking the inlet or outlet of the pod pump which would inhibit continuous flow.
  • the raised flow path 30 is shown in the exemplary embodiment having particular dimensions, however, in alternate embodiments, as seen in FIGS. 18A-18E , the raised flow path 30 is narrower, or in still other embodiments, the raised flow path 30 can be any dimensions as the purpose is to control fluid flow so as to achieve a desired flow rate or behavior of the fluid.
  • the dimensions shown and described here with respect to the raised flow path, the pod pumps, the valves or any other aspect are mere exemplary and alternate embodiments. Other embodiments are readily apparent.
  • a balancing pod is constructed similar to the pod pump described above with respect to FIG. 1A .
  • a balancing pod includes two fluid balancing chambers, rather than an actuation chamber and a pumping chamber, and does not include an actuation port.
  • each balancing chamber includes an inlet 102 and an outlet 104 .
  • a groove 126 is included on each of the balancing chamber walls 120 , 122 . The groove 126 is described in further detail below.
  • the membrane 112 provides a seal between the two chambers.
  • the balancing chambers work to balance the flow of fluid into and out of the chambers such that both chambers maintain an equal volume rate flow.
  • the inlets 102 and outlets 104 for each chamber are shown to be on the same side, in other embodiments, the inlets 102 and outlets 104 for each chamber are on different sides. Also, the inlets 102 and outlets 104 can be on either side, depending on the flow path in which the balancing chamber is integrated.
  • the membrane 112 includes an embodiment similar to the one described below with respect to FIG. 6A-6G .
  • the membrane 112 can be over molded or otherwise constructed such that a double-ring seal is not applicable.
  • the metering pump can he any pump that is capable of adding any fluid or removing any fluid.
  • the fluids include but are not limited to pharmaceuticals, inorganic compounds or elements, organic compounds or elements, nutraceuticals, nutritional elements or compounds or solutions, or any other fluid capable of being pumped.
  • the metering pump is a membrane pump.
  • the metering pump is a smaller volume pod pump.
  • the metering pump includes an inlet and an outlet, similar to a larger pod pump (as shown in FIG. 1A for example). However, the inlet and outlet are generally much smaller than a pod pump and, in one exemplary embodiment, includes a volcano valve-like raised ring around either the inlet or outlet.
  • Metering pumps include a membrane, and various embodiments of a metering pump membrane are shown in FIGS. 5E-5H .
  • the metering pump in some embodiments, pumps a volume of fluid out of the fluid line. Once the fluid is in the pod pump, a reference chamber, located outside the cassette, using the FMS, determines the volume that has been removed.
  • this volume of fluid that has been removed will not then flow to the fluid outlet, the balance chambers or to a pod pump.
  • the metering pump is used to remove a volume of fluid from a fluid line. In other embodiments, the metering pump is used to remove a volume of fluid to produce other results.
  • FMS may be used to perform certain fluid management system measurements, such as, for example, measuring the volume of subject fluid pumped through the pump chamber during a stroke of the membrane or detecting air in the pumping chamber, e.g., using techniques described in U.S. Pat. Nos. 4,808,161; 4,826,482; 4,976,162; 5,088,515; and 5,350,357, which are hereby incorporated herein by reference in their entireties.
  • Metering pumps are also used in various embodiments to pump a second fluid info the fluid line, in some embodiments, the metering pump is used to pump a therapeutic or a compound into a fluid line.
  • the metering pump uses the metering pump to pump a volume of compound into a mixing chamber in order to constitute a solution.
  • the metering pumps are configured for FMS volume measurement. In other embodiments, the metering pumps are not.
  • a small fixed reference air chamber is located outside of the cassette, for example, in the pneumatic manifold (not shown).
  • a valve isolates the reference chamber and a second pressure sensor.
  • the stroke volume of the metering pump may be precisely computed by charging the reference chamber with air, measuring the pressure, and then opening the valve to the pumping chamber.
  • the volume of air on the chamber side may be computed based on the fixed volume of the reference chamber and the change in pressure when the reference chamber was connected to the pump chamber.
  • the exemplary embodiment of the cassette includes one or more valves. Valves are used to regulate flow by opening and closing fluid lines.
  • the valves included in the various embodiments of the cassette include one or more of the following: volcano valves or smooth valves. In some embodiment of the cassette, check valves may be included Embodiments of the volcano valve are shown in FIGS. 2A and 2B , while an embodiment of the smooth valve is shown in FIG. 2C . Additionally, FIGS. 3 and 4 show cross sections of one embodiment of a pod pump in a cassette with an inlet and an outlet valve.
  • reciprocating positive-displacement pumps of the types just described may include, or may be used in conjunction with, various valves to control fluid flow through the pump.
  • the reciprocating positive-displacement pump or the balancing pods may include, or be used in conjunction with, an inlet valve and/or an outlet valve.
  • the valves may be passive or active.
  • the membrane is urged back and forth by positive and negative pressurizations, or by positive and vent to atmosphere pressurizations, of a gas provided through the pneumatic port, which connects the actuation chamber to a pressure actuation system.
  • active valves control the fluid flow through the pump(s) and the cassette.
  • the active valves may be actuated by a controller in such a manner as to direct flow in a desired direction.
  • a controller in such a manner as to direct flow in a desired direction.
  • Such an arrangement would generally permit the controller to cause flow in either direction through the pod pump.
  • the flow would normally be in a first direction, e.g., from the inlet, to the outlet. At certain other times, the flow may be directed in the opposite direction, e.g., from the outlet to the inlet.
  • Such reversal of flow may be employed, for example, during priming of the pump, to check for an aberrant line condition (e.g., a line occlusion, blockage, disconnect, or leak), or to clear an aberrant line condition (e.g., to try to dislodge a blockage).
  • an aberrant line condition e.g., a line occlusion, blockage, disconnect, or leak
  • an aberrant line condition e.g., to try to dislodge a blockage
  • Pneumatic actuation of valves provides pressure control and a natural limit to the maximum pressure that may be developed in a system.
  • pneumatic actuation has the added benefit of providing the opportunity to locate all the solenoid control valves on one side of the system away from the fluid paths.
  • the volcano valves are pneumatically controlled valves that may be used in embodiments of the cassette.
  • a membrane 202 along with the midplate 204 , defines a valving chamber 206 .
  • Pneumatic pressure is provided through a pneumatic port 208 to either force, with positive gas pressure, the membrane 202 against a valve seat 210 to close the valve, or to draw, with negative gas pressure, or in some embodiments, with vent to atmospheric pressure, the membrane away from the valve seat 210 to open the valve.
  • a control gas chamber 212 is defined by the membrane 202 , the top plate 214 , and the midplate 204 .
  • the midplate 204 has an indentation formed on it, into which the membrane 202 is placed so as to form the control gas chamber 212 on one side of the membrane 202 and the valving chamber 206 on the other side.
  • the pneumatic port 208 is defined by a channel formed in the top plate 214 .
  • valves can be ganged together so that all the valves ganged together can be opened or closed at the same time by a single source of pneumatic pressure.
  • Channels formed on the midplate 204 corresponding with fluid paths along with the bottom plate 216 , define the valve inlet 218 and the valve outlet 220 . Holes formed through the midplate 204 provide communication between the inlet 218 and the valving chamber 206 and between the valving chamber 206 and the outlet 220 .
  • the membrane 202 is provided with a thickened rim 222 , which fits tightly in a groove 224 in the midplate 204 .
  • the membrane 202 can be placed in and held by the groove 224 before the top plate 214 is connected to the midplate 204 .
  • this valve design may impart benefits in manufacturing.
  • the top plate 214 may include additional material extending into control gas chamber 212 so as to prevent the membrane 202 from being urged too much in a direction away from the groove 224 , so as to prevent the membrane's thickened rim 222 from popping out of the groove 224 .
  • the location of the pneumatic port 208 with respect to the control gas chamber 212 varies in the two embodiments shown in FIGS. 2A and 2B .
  • FIG. 2C shows an embodiment in which the valving chamber lacks a valve seat feature. Rather, in FIG. 2C , the valve in this embodiment does not include any volcano features and thus, the valving chamber 206 , i.e., the fluid side, does not include any raised features and thus is smooth. This embodiment is used in cassettes used to pump fluid sensitive to shearing.
  • FIG. 2D shows an embodiment in which the valving chamber has a raised area to aid in the sealing of the valving membrane.
  • FIGS. 2E-2G various embodiments of the valve membrane are shown. Although some exemplary embodiments have been shown and described, in other embodiments, variations of the valve and valving membrane may be used.
  • the membrane has a variable cross-sectional thickness, as shown in FIG. 4 .
  • Thinner, thicker or variable thickness membranes may be used to accommodate the strength, flexural and other properties of the chosen membranes materials.
  • Thinner, thicker or variable membrane wall thickness may also be used to manage the membrane thereby encouraging it to flex more easily in some areas than in other areas, thereby aiding in the management of pumping action and flow of subject fluid in the pump chamber.
  • the membrane is shown having its thickest cross-sectional area closest to its center.
  • the thickest and thinnest areas may be in any location on the membrane.
  • the thinner cross-section may be located near the center and the thicker cross-sections located closer to the perimeter of the membrane. Still other configurations are possible.
  • FIGS. 5A-5D one embodiment of a membrane is shown having various surface embodiments, these include smooth ( FIG. 5A ), rings ( FIG. 5D ), ribs ( FIG. 5C ), dimples or dots ( FIG. 5B ) of variable thickness and or geometry located at various locations on the actuation and or pumping side of the membrane.
  • the membrane has a tangential slope in at least one section, but in other embodiments, the membrane is completely smooth or substantially smooth.
  • the membrane has a dimpled or dotted surface.
  • the membrane may be made of any flexible material having a desired durability and compatibility with the subject fluid.
  • the membrane can be made from any material that may ilex in response to fluid, liquid or gas pressure or vacuum applied to the actuation chamber.
  • the membrane material may also be chosen for particular bio-compatibility, temperature compatibility or compatibility with various subject fluids that may be pumped by the membrane or introduced to the chambers to facilitate movement of the membrane.
  • the membrane is made from high elongation silicone.
  • the membrane is made from any elastomer or rubber, including, but not limited to, silicone, urethane, nitrile, EPDM or any other rubber, elastomer or flexible material.
  • the shape of the membrane is dependent on multiple variables. These variables include, but are not limited to; the shape of the chamber; the size of the chamber; the subject fluid characteristics; the volume of subject fluid pumped per stroke; and the means or mode of attachment of the membrane to the housing.
  • the size of the membrane is dependent on multiple variables. These variables include, but are not limited to: the shape of the chamber; the size of the chamber; the subject fluid characteristics; the volume of subject fluid pumped per stroke; and the means or mode of attachment of the membrane to the housing. Thus, depending on these or other variables, the shape and size of the membrane may vary in various embodiments.
  • the membrane can have any thickness. However, in some embodiments, the range of thickness is between 0.002 inches to 0.125 inches. Depending on the material used for the membrane, the desired thickness may vary. In one embodiment, high elongation silicone is used in a thickness ranging from 0.015 inches to 0.050 inches. However in other embodiments, the thickness may vary.
  • the membrane is pre-formed to include a substantially dome-shape in at least part of the area of the membrane.
  • a substantially dome-shape in at least part of the area of the membrane.
  • FIGS. 4E and 4F One embodiment of the dome-shaped membrane is shown in FIGS. 4E and 4F . Again, the dimensions of the dome may vary based on some or more of the variables described above. However, in other embodiments, the membrane may not include a pre-formed dome shape.
  • the membrane dome is formed using liquid injection molding.
  • the dome may be formed by using compression molding.
  • the membrane is substantially flat.
  • the dome size, width or height may vary.
  • the membrane may be held in place by various means and methods.
  • the membrane is clamped between the portions of the cassette, and in some of these embodiments, the rim of the cassette may include features to grab the membrane.
  • the membrane is clamped to the cassette using at least one bolt or another device.
  • the membrane is over-molded with a piece of plastic and then the plastic is welded or otherwise attached to the cassette.
  • the membrane is pinched between the mid plate described with respect to FIGS. 1A and 1B and the bottom plate.
  • any method or means for attaching the membrane to the cassette can be used.
  • the membrane in one alternate embodiment, is attached directly to one portion of the cassette.
  • the membrane is thicker at the edge, where the membrane is pinched by the plates, than in other areas of the membrane. In some embodiments, this thicker area is a gasket, in some embodiments an O-ring, ring or any other shaped gasket.
  • a gasket in some embodiments an O-ring, ring or any other shaped gasket.
  • the membrane is shown with two gaskets 62 , 64 . In some of these embodiments, the gasket(s) 62 , 64 provides the attachment, point of the membrane to the cassette. In other embodiments, the membrane includes more than two gaskets. Membranes with one gasket are also included in some embodiments (see FIGS. 4A-4D ).
  • the gasket is contiguous with the membrane. However, in other embodiments, the gasket is a separate part of the membrane. In some embodiments, the gasket is made from the same material as the membrane. However, in other embodiments, the gasket is made of a material different from the membrane. In some embodiments, the gasket, is formed by over-molding a ring around the membrane. The gasket can be any shape ring or seal desired so as to complement the pod pump housing embodiment. In some embodiments, the gasket is a compression type gasket.
  • a mixing pod includes a chamber for mixing.
  • the mixing pod is a flexible structure, and in some embodiments, at least a section of the mixing pod is a flexible structure.
  • the mixing pod can include a seal, such as an o-ring, or a membrane.
  • the mixing pod can be any shape desired, in the exemplary embodiment, the mixing pod is similar to a pod pump except it does not include a membrane and does not include an actuation port.
  • Some embodiments of this embodiment of the mixing pod include an o-ring seal to seal the mixing pod chamber.
  • the mixing pod is a spherical hollow pod with a fluid inlet and a fluid outlet.
  • the chamber size can be any size desired.
  • FIG. 7 is a schematic showing an embodiment of a pressure actuation system that may be used to actuate a pod pump with both positive and negative pressure, such as the pod pump shown in FIG. 1A .
  • the pressure actuation system is capable of intermittently or alternately providing positive and negative pressurizations to the gas in the actuation chamber of the pod pump.
  • FIG. 7 does not apply in these embodiments, actuation of the pod pump is accomplished by applying positive pressure and vent to atmosphere (again, not shown in FIG. 7 ).
  • the pod pump including the flexible membrane, the inlet, the outlet, the pneumatic port, the pumping chamber, the actuation chamber, and possibly including an inlet check valve and an outlet check valve or other valves—is part of a larger disposable system.
  • the pneumatic actuation system including an actuation-chamber pressure transducer, a positive-supply valve, a negative-supply valve, a positive-pressure gas reservoir, a negative-pressure gas reservoir, a positive-pressure-reservoir pressure transducer, a negative-pressure-reservoir pressure transducer, as well as an electronic controller including, in some embodiments, a user interface console (such as a touch-panel screen)—may be part of a base unit.
  • the positive-pressure reservoir provides to the actuation chamber the positive pressurization of a control gas to urge the membrane towards a position where the pumping chamber is at its minimum volume (i.e., the position where the membrane is against the rigid pumping-chamber wall).
  • the negative-pressure reservoir provides to the actuation chamber the negative pressurization of the control gas to urge the membrane in the opposite direction, towards a position where the pumping chamber is at its maximum volume (i.e., the position where the membrane is against the rigid actuation-chamber wall).
  • a valving mechanism is used to control fluid communication between each of these reservoirs and the actuation chamber.
  • a separate valve is used for each of the reservoirs; a positive-supply valve controls fluid communication between the positive-pressure reservoir and the actuation chamber, and a negative-supply valve controls fluid communication between the negative-pressure reservoir and the actuation chamber.
  • These two valves are controlled by the controller.
  • a single three-way valve may be used in lieu of the two separate valves.
  • the valves may be binary on-off valves or variable-restriction valves.
  • the controller also receives pressure information from the three pressure transducers: an actuation-chamber pressure transducer, a positive-pressure-reservoir pressure transducer, and a negative-pressure-reservoir pressure transducer. As their names suggest, these transducers respectively measure the pressure in the actuation chamber, the positive-pressure reservoir, and the negative-pressure reservoir.
  • the actuation-chamber-pressure transducer is located in a base unit but is in fluid communication with the actuation chamber through the pod pump pneumatic port.
  • the controller monitors the pressure in the two reservoirs to ensure they are properly pressurized (either positively or negatively).
  • the positive-pressure reservoir may be maintained at around 750 mmHG, while the negative-pressure reservoir may be maintained at around ⁇ 450 mmHG.
  • a compressor-type pump or pumps may be used to maintain the desired pressures in these reservoirs.
  • two independent compressors may be used to respectively service the reservoirs.
  • Pressure in the reservoirs may be managed using a simple bang-bang control technique in which the compressor servicing the positive-pressure reservoir is turned on if the pressure in the reservoir falls below a predetermined threshold and the compressor servicing the negative-pressure reservoir is turned on if the pressure in the reservoir is above a predetermined threshold.
  • the amount of hysteresis may be the same for both reservoirs or may be different. Tighter control of the pressure in the reservoirs can be achieved by reducing the size of the hysteresis band, although this will generally result in higher cycling frequencies of the compressors. If very tight control of the reservoir pressures is required or otherwise desirable for a particular application, the bang-bang technique could be replaced with a PID control technique and could use PWM signals on the compressors.
  • the pressure provided by the positive-pressure reservoir is preferably strong enough—under normal conditions—to urge the membrane all the way against the rigid pumping-chamber wall.
  • the negative pressure (i.e., the vacuum) provided by the negative-pressure reservoir is preferably strong enough—under normal conditions—to urge the membrane all the way against the actuation-chamber wall.
  • these positive and negative pressures provided by the reservoirs are within safe enough limits that even with either the positive-supply valve or the negative-supply valve open all the way, the positive or negative pressure applied against the membrane is not so strong as to damage the pod pump or create unsafe fluid pressures (e.g., that may harm a patient receiving pumped blood or other fluid).
  • pneumatic actuation systems may be used to move the membrane back and forth instead of the two-reservoir pneumatic actuation system shown in FIG. 7 , although a two-reservoir pneumatic actuation system is generally preferred.
  • alternative pneumatic actuation systems may include either a single positive-pressure reservoir or a single negative-pressure reservoir along with a single supply valve and a single tank pressure sensor, particularly in combination with a resilient membrane.
  • Such pneumatic actuation systems may intermittently provide either a positive gas pressure or a negative gas pressure to the actuation chamber of the pod pump.
  • the pump may be operated by intermittently providing positive gas pressure to the actuation chamber, causing the membrane to move toward the pumping chamber wall and expel the contents of the pumping chamber, and releasing the gas pressure, causing the membrane to return to its relaxed position and draw fluid into the pumping chamber.
  • the pump may be operated by intermittently providing negative gas pressure to the actuation chamber, causing the membrane to move toward the actuation chamber wall and draw fluid into the pumping chamber, and releasing the gas pressure, causing the membrane to return to its relaxed position and expel fluid from the pumping chamber.
  • a fluid valve in the exemplary embodiment consists of a small chamber with a flexible membrane or membrane across the center dividing the chamber into a fluid half and a pneumatic half.
  • the fluid valve in the exemplary embodiment, has 3 entry/exit ports, two on the fluid half of the chamber and one the pneumatic half of the chamber.
  • the port on the pneumatic half of the chamber can supply either positive pressure or vacuum (or rather than vacuum, in some embodiments, there is a vent to atmosphere) to the chamber.
  • a vacuum is applied to the pneumatic portion of the chamber, the membrane is pulled towards the pneumatic side of the chamber, clearing the fluid path and allowing fluid to flow into and out of the fluid side of the chamber.
  • the membrane When positive pressure is applied to the pneumatic portion of the chamber, the membrane is pushed towards the fluid side of the chamber, blocking the fluid path and preventing fluid flow.
  • the membrane In the volcano valve embodiment (as shown in FIGS. 2A-2B ) on one of the fluid ports, that port seals off first when closing the valve and the remainder of any fluid in the valve is expelled through the port without the volcano feature.
  • the raised feature between the two ports allows for the membrane to seal the two ports from each other earlier in the actuation stroke (i.e., before the membrane seals the ports directly).
  • pressure valves are used to operate the pumps located at different points in the flow path.
  • This architecture supports pressure control by using two variable-orifice valves and a pressure sensor at each pump chamber which requires pressure control.
  • one valve is connected to a high-pressure source and the other valve is connected to a low-pressure sink.
  • a high-speed control loop monitors the pressure sensor and controls the valve positions to maintain the necessary pressure in the pump chamber.
  • Pressure sensors are used to monitor pressure in the pneumatic portion of the chambers themselves. By alternating between positive pressure and vacuum on the pneumatic side of the chamber, the membrane is cycled back and forth across the total chamber volume. With each cycle, fluid is drawn through the upstream valve of the inlet fluid port when the pneumatics pull a vacuum on the pods. The fluid is then subsequently expelled through the outlet port and the downstream valve when the pneumatics deliver positive pressure to the pods.
  • pressure pumps consist of a pair of chambers. When the two chambers are run 180 degrees out of phase from one another the flow is essentially continuous.
  • pressure pod pumps which can defect end-of-stroke.
  • An outer control loop determines the correct pressure values to deliver the required flow.
  • Pressure pumps can run an end of stroke algorithm to detect when each stroke completes. While the membrane is moving, the measured pressure in the chamber tracks a desired sinusoidal pressure. When the membrane contacts a chamber wall, the pressure becomes constant, no longer tracking the sinusoid. This change in the pressure signal is used to detect when the stroke has ended, i.e., the end of stroke.
  • the pressure pumps have a known volume.
  • an end of stroke indicates a known volume of fluid is in the chamber.
  • fluid flow may be controlled using rate equating to volume.
  • FMS may be used to determine the volume of fluid pumped by the metering pumps.
  • the metering pump may pump fluid without using the FMS volume measurement system, however, in the exemplary embodiments, the FMS volume measurement system is used to calculate the exact volume of fluid pumped.
  • first valving path an inlet can be an outlet, as well, an indication of a first, second, third fluid does not denote that they are different fluids or are in a particular hierarchy.
  • the denotations simply refer to separate entrance areas into the cassette and the first, second, third, etc, fluids may be different fluids or the same fluid types or composition or two or more may be the same.
  • the designation of the first, second, third, etc. valving paths do not have any particular meaning, but are used for clearness of description.
  • fluid inlets which can also be fluid outlets
  • first, fluid outlet, second fluid outlet merely indicate that a fluid may travel out of or into the cassette via that inlet/outlet.
  • more than one inlet/outlet on the schematic is designated with an identical name. This merely describes that all of the inlet/outlets having that designation are pumped by the same metering pump or set of pod pumps (which in alternate embodiments, can be a single pod pump).
  • the cassette 800 includes at least one pod pump 828 , 820 and at least one mixing chamber 818 .
  • the cassette 800 also includes a first fluid inlet 810 , where a first fluid enters the cassette.
  • the first fluid includes a flow rate provided by one of the at least one pod pump 820 , 828 in the cassette 800 .
  • the cassette 800 also includes a first fluid outlet 824 where fluid exits the cassette 800 having a flow rate provided by one of the at least one pod pump 820 , 828 .
  • the cassette 800 includes at least one metering fluid line 812 , 814 , 816 that is in fluid connection with the first fluid outlet.
  • the cassette also includes at least one second fluid inlet 826 where the second fluid enters the cassette 800 .
  • a third fluid inlet 825 is also included.
  • Metering pumps 822 , 830 pump the second fluid and the third fluid into the first fluid outlet line.
  • the second fluid and, in some embodiments, the third fluid, connected to the cassette 800 at the second fluid inlet 826 and third fluid inlet 825 respectively, are each fluidly connected to a metering pump 822 , 830 and to the first fluid outlet line through a metering fluid line 812 , 814 , 816 .
  • the metering pumps 822 , 830 described in more detail below, in the exemplary embodiment, include a volume measurement capacity such that the volume of fluid pumped by the metering pumps 822 , 830 is readily discernible.
  • the mixing chamber 818 is connected to the first fluid outlet line 824 and includes a fluid inlet and a fluid outlet.
  • sensors are located upstream and downstream from the mixing chamber 818 . The location of the sensors in the exemplary embodiment are shown and described below with respect to FIGS. 14C , 14 D and FIGS. 15B and 15C .
  • the cassette 800 is capable of internally mixing a solution made up of at least two components.
  • the cassette 800 also includes the capability of constituting a powder to a fluid prior to pumping the fluid into the mixing chamber. These capabilities will be described in greater detail below.
  • valves 832 - 860 impart the various capabilities of the cassette 800 .
  • the components of the cassette 800 may be used differently in the different embodiments based on various valving controls.
  • the fluid schematic of the cassette 800 shown in FIG. 8 may be embodied into various cassette apparatus.
  • the embodiments of the cassette 800 including the fluid schematic shown in FIG. 8 are not the only cassette embodiments that may incorporate this or an alternate embodiment of this fluid schematic.
  • the types of valves, the ganging of the valves, the number of pumps and chambers may vary in various cassette embodiments of this fluid schematic.
  • a fluid flow-path schematic 800 is shown with the fluid paths indicated based on different valving flow paths.
  • the fluid flow-path schematic 800 is described herein corresponding to the valving flow paths in one embodiment of the cassette.
  • the exemplary embodiment of the midplate 900 of the cassette are shown in FIG. 10 with the valves indicated corresponding to the respective fluid flow-path schematic 800 in FIG. 8 .
  • the fluid flow paths will be described based on the valving.
  • the term “valving path” refers to a fluid path that may, in some embodiments, be available based on the control of particular valves.
  • the corresponding fluid side structures of FIG. 10 are shown in FIG. 12A .
  • the first valving path includes valves 858 , 860 .
  • This valving path 858 , 860 includes the metering fluid line 812 , which connects to the second fluid inlet 826 .
  • these two second fluid inlets 826 can be connected to the same fluid source or a different fluid source. Either way, the same fluid or a different fluid may be connected to each second fluid inlet 826 .
  • Each second fluid inlet 826 is connected to a different metering fluid line 812 , 814 .
  • the first of the two metering fluid lines connected to the second fluid inlet 826 is as follows.
  • valve 858 opens and valve 860 is closed and metering pump 822 is actuated, fluid is drawn from the second fluid inlet 826 and into metering fluid line 812 .
  • valve 860 is open and valve 858 is closed and the metering pump 822 is actuated, second fluid continues on metering fluid line 812 into pod pump 820 .
  • valve 842 when valve 842 is open and pod pump 820 is actuated, fluid is pumped from pod pump 820 to one of the third fluid inlet 825 .
  • this valving path is provided to send liquid into a container or source connected to third fluid inlet 825 .
  • this valving path 832 , 835 includes the metering fluid line 816 , which connects to the third fluid inlet 825 .
  • the metering fluid line 816 connects to the third fluid inlet 825 .
  • these two third fluid inlets 825 can be connected to the same fluid source or a different fluid source. Either way, the same fluid or a different fluid may be connected to each third fluid inlet 825 .
  • Each third fluid inlet 825 is connected to a different metering fluid line 862 , 868 .
  • valve 832 opens and valve 836 is closed and metering pump 830 is actuated, fluid is drawn from the third fluid inlet 825 and into metering fluid line 830 .
  • valve 836 is open and valve 832 is closed and the metering pump 830 is actuated, third fluid continues on metering fluid line 816 into first fluid outlet line 824 .
  • valve 846 when valve 846 is open and pod pump 820 is actuated, fluid is pumped from pod pump 820 to one of the third fluid inlet 825 .
  • this valving path is provided to send liquid into a container or source connected to third fluid inlet 825 .
  • valve 850 opens and pod pump 820 is actuated, fluid is pumped into the cassette 800 through the first fluid inlet 810 , and into pod pump 820 .
  • valve 838 when valve 838 is open and pod pump 820 is actuated, fluid is pumped from pod pump 820 to the mixing chamber 818 and to the first fluid outlet 824 .
  • the seventh valving path includes valves 858 , 856 .
  • This valving path 858 , 856 includes the metering fluid line 812 , which connects to the second fluid inlet 826 .
  • these two second fluid inlets 826 can be connected the same fluid source or a different fluid source. Either way, the same fluid or a different fluid may be connected to each second fluid inlet 826 .
  • Each second fluid inlet 826 is connected to a different metering fluid line 812 , 814 .
  • valve 858 opens and valve 856 is closed and metering pump 822 is actuated, fluid is drawn from the second fluid inlet 826 and info metering fluid line 812 .
  • valve 856 is open and valve 858 is closed, and the metering pump is actuated, second fluid continues on metering fluid line 814 into pod pump 828 .
  • valve 848 when valve 848 is open and pod pump 828 is actuated, fluid is pumped from pod pump 828 to one of the third fluid inlet 825 .
  • this valving path is provided to send fluid/liquid into a container or source connected to third fluid inlet 825 .
  • valve 844 when valve 844 is open and pod pump 828 is actuated, fluid is pumped from pod pump 828 to one of the third fluid inlet 825 .
  • this valving path is provided to send liquid into a container or source connected to third fluid inlet 825 .
  • valve 848 when valve 848 is open and pod pump 828 is actuated, fluid is pumped from pod pump 828 to one of the third fluid inlet 825 .
  • this valving path is provided to send fluid/liquid into a container or source connected to third fluid inlet 825 .
  • the eleventh valving path including valves 854 and 856 is shown.
  • This valving path 854 , 856 includes the metering fluid line 814 , which connects to the second fluid inlet 826 .
  • these two second fluid inlets 826 can be connected the same fluid source or a different fluid source. Either way, the same fluid or a different fluid may be connected to each second fluid inlet 826 .
  • Each second fluid inlet 826 is connected to a different metering fluid line 812 , 814 .
  • the second of the two metering fluid lines connected to the second fluid inlet 826 is shown in FIG. 8 .
  • the twelfth valving path is as follows. When valve 854 opens and valve 856 is closed and metering pump 822 is actuated, fluid is drawn from the second fluid inlet 826 and into metering fluid line 814 . When valve 856 is open and valve 854 is closed and the metering pump 822 is actuated, the second fluid continues on metering fluid line 814 into pod pump 828 .
  • valve 854 opens and valve 860 is closed and metering pump 822 is actuated, fluid is drawn from the second fluid inlet 826 and into metering fluid line 814 .
  • valve 860 is open and valve 854 is closed, and the metering pump 822 is actuated, the second fluid continues on metering fluid line 814 into pod pump 820 .
  • valve 852 opens and pod pump 828 is actuated, fluid is pumped into the cassette 800 through the first fluid inlet 810 , and into pod pump 828 .
  • valve 840 when valve 840 is open and pod pump 828 is actuated, fluid is pumped from pod pump 828 to the mixing chamber 818 and to the first fluid outlet 824 .
  • the sixteenth valving path including valve 834 when valve 834 is open and valve 836 opens, and the metering pump 830 is actuated, fluid from the third fluid inlet 825 flows on metering fluid line 862 and to metering fluid line 816 .
  • valves are open individually.
  • the valves are pneumatically open.
  • the fluid valves are volcano valves, as described in more detail in this specification.
  • the top plate 1100 of exemplary embodiment of the cassette is shown.
  • the pod pumps 820 , 828 and the mixing chambers 818 on the top plate 1100 are formed in a similar fashion.
  • the pod pumps 820 , 828 and mixing chamber 818 when assembled with the bottom plate, have a total volume of capacity of 38 ml.
  • the mixing chamber can have any size volume desired.
  • FIG. 11B the bottom view of the top plate 1100 is shown.
  • the fluid paths are shown in this view. These fluid paths correspond to the fluid paths shown in FIGS. 12A-12B in the midplate 1200 .
  • the top plate 1100 and the top of the midplate 1200 form the liquid or fluid side of the cassette for the pod pumps 820 , 828 and for one side of the mixing chamber 818 . Thus, most of the liquid flow paths are on the top 1100 and midplates 1200 .
  • FIG. 12B the first fluid inlet 810 and the first fluid outlet 824 are shown.
  • the pod pumps 820 , 828 include a groove 1002 (in alternate embodiments, this is a groove).
  • the groove 1002 is shown having a particular size and shape, however, in other embodiments, the size and shape of the groove 1002 can be any size or shape desirable.
  • the size and shape shown in FIGS. 11 A and 11 B is the exemplary embodiment.
  • the groove 1002 forms a path between the fluid inlet side and the fluid outlet side of the pod pumps 820 , 828 .
  • the groove 1002 is a groove in the inner pumping chamber wall of the pod pump.
  • the groove 1002 provides a fluid path whereby when the membrane is at the end-of-stroke there is still a fluid path between the inlet and outlet such that the pockets of fluid or air do not get trapped in the pod pump.
  • the groove 1002 is included in both the liquid/fluid and air/actuation sides of the pod pumps 820 , 828 .
  • the groove 1002 may also be included in the mixing chamber 818 (see FIGS. 13A-13B with respect to the actuation/air side of the pod pumps 820 , 828 and the opposite side of the mixing chamber 818 .
  • the groove 1002 is either not included or on only one side of the pod pumps 820 , 828 .
  • the liquid/fluid side of the pod pumps 820 , 828 may include a feature (not shown) whereby the inlet and outlet flow paths are continuous and a rigid outer ring (not shown) is molded about the circumference of the pumping chamber is also continuous. This feature allows for the seal, formed with the membrane (not shown) to be maintained.
  • FIG. 11E the side view of the exemplary embodiment of the top plate 1100 is shown.
  • FIGS. 12A-12B the exemplary embodiment of the midplate 1200 is shown.
  • the midplate 1200 is also shown in FIGS. 9A-9F and 10 A- 10 F, where these FIGS. correspond with FIGS. 12A-12B .
  • FIGS. 9A-9F and 10 A- 10 F indicate the locations of the various valves and valving paths.
  • the locations of the membranes (not shown) for the respective pod pumps 820 , 828 as well as the location of the mixing chamber 818 are shown.
  • sensor elements are incorporated into the cassette so as to discern various properties of the fluid being pumped.
  • three sensor elements are included.
  • six sensor elements (two sets of three) are included.
  • the sensor elements are located in the sensor cell 1314 , 1316 .
  • a sensor cell 1314 , 1316 is included as an area on the cassette for sensor(s) elements.
  • the three sensor elements of the two sensor cells 1314 , 1316 are housed in respective sensor elements housings 1308 , 1310 , 1312 and 1318 , 1320 , 1322 .
  • two of the sensor elements housings 1308 , 1312 and 1318 , 1320 accommodate a conductivity sensor elements and the third sensor elements housing 1310 , 1322 accommodates a temperature sensor elements.
  • the conductivity sensor elements and temperature sensor elements can be any conductivity or temperature sensor elements in the art.
  • the conductivity sensors are graphite posts.
  • the conductivity sensor elements are posts made from stainless steel, titanium, platinum or any other metal coated to be corrosion resistant and still be electrically conductive.
  • the conductivity sensor elements will include an electrical lead that transmits the probe information to a controller or other device.
  • the temperature sensor is a thermister potted in a stainless steel probe.
  • a combination temperature and conductivity sensor elements is used similar to the one described U.S. Patent Application entitled Sensor Apparatus Systems, Devices and Methods filed Oct. 12, 2007 (DEKA-024XX).
  • FIG. 12C the side view of the exemplary embodiment of the midplate 1200 is shown.
  • FIGS. 13A-13B the bottom plate 1300 is shown.
  • the inner or inside surface of the bottom plate 1300 is shown.
  • the inner or inside surface is the side that contacts the bottom surface of the midplate (not shown, see FIG. 9B ).
  • the bottom plate 1300 attaches to the air or actuation lines (not shown).
  • the corresponding entrance holes for the air that actuates the pod pumps 820 , 828 and valves (not shown, see FIGS. 10A-10F ) in the midplate 1300 can be seen.
  • Holes 810 , 824 correspond to the first fluid inlet and first fluid outlet shown in FIG. 12B , 810 , 824 respectively.
  • the corresponding halves of the pod pumps 820 , 828 and mixing chamber 818 are also shown, as are the grooves 1002 for the fluid paths.
  • the actuation holes in the pumps are also shown.
  • the bottom plate 1300 corresponding halves of the pod pumps 820 , 828 and mixing chamber 818 make apparent the difference between the pod pumps 820 , 828 and mixing chamber 818 .
  • the pod pumps 820 , 828 include an air/actuation path on the bottom plate 1300 , while the mixing chamber 818 has identical construction to the half in the top plate.
  • the mixing chamber 818 mixes liquid and therefore, does not include a membrane (not shown) nor an air/actuation path.
  • the sensor cell 1314 , 1316 with the three sensor element housings 1308 , 1310 , 1312 and 1318 , 1320 , 1322 are also shown.
  • the actuation ports 1306 are shown on the outside or outer bottom plate 1300 .
  • An actuation source is connected to these actuation ports 1306 .
  • the mixing chamber 818 does not have an actuation port as it is not actuated by air.
  • FIG. 13C a side view of the exemplary embodiment of the bottom plate 1300 is shown.
  • the membrane is a gasket o-ring membrane as shown in FIG. 5A .
  • a gasket o-ring membranes having texture including, but not limited to, the various embodiments in FIG. 4D , or 5 B- 5 D may be used.
  • the membranes shown in FIGS. 6A-6G may also be used.
  • FIGS. 14C and 14D are an exploded view of the exemplary embodiment of the cassette 1400 .
  • the membranes 1600 are shown.
  • the membrane for the pod pumps is identical.
  • any membrane may be used, and one pod pump could use one embodiment of the membrane while the second pod pump can use a different embodiment of the membrane (or each pod pump can use the same membrane).
  • the various embodiments of the membrane used in the metering pumps 1604 are shown in more detail in FIGS. 5E-5H .
  • the various embodiments of the membrane used in the valves 1222 is shown in more detail in FIGS. 2E-2G .
  • the metering pump membrane as well as the valve membranes may contain textures for example, but not limited to, the textures shown on the pod pump membranes shown in FIGS. 5A-5D .
  • FIGS. 14C and 14D One embodiment of the conductivity sensor elements 1314 , 1316 and the temperature sensor element 1310 , which make up the sensor cell 1322 , are also shown in FIGS. 14C and 14D . Still referring to FIGS. 14C and 14D , the sensor elements are housed in sensor blocks (shown as 1314 , 1316 in FIGS. 12B and 13A ) which include areas on the bottom plate 1300 and the midplate 1200 . O-rings seal the sensor housings from the fluid lines located on the upper side of the midplate 1200 and the inner side of the top plate 1100 . However, in other embodiments, an o-ring is molded into the sensor block or any other method of sealing can be used.
  • FIGS. 15A-15C various cross sectional views of the assembled cassette are shown.
  • the membranes 1602 are shown in a pod pumps 820 , 828 .
  • the o-ring of the membrane 1602 is sandwiched by the midplate 1200 and the bottom plate 1300 .
  • a valve membrane 1606 can also be seen. As discussed above, each valve includes a membrane.
  • the two conductivity sensors 1308 , 1312 and the temperature sensor 1310 are shown. As can be seen from the cross section, the sensors 1308 , 1310 , 1312 are in the fluid line 824 . Thus, the sensors 1308 , 1310 , 1312 are in fluid connection with the fluid line and can determine sensor data of the fluid exiting fluid outlet one 824 . Still referring to FIG. 15B , a valve 836 cross section is shown. As shown in this FIG., in the exemplary embodiment, the valves are volcano valves similar to the embodiment shown and described above with respect to FIG. 2B . However, as discussed above, in alternate embodiment, other valves are used including, but not limited, to those described and shown above with respect to FIGS. 2A , 2 C and 2 D.
  • the two conductivity sensor elements 1318 , 1320 and the temperature sensor element 1322 are shown. As can be seen from the cross section, the sensor elements 1318 , 1320 , 1322 are in the fluid line 824 . Thus, the sensor elements 1318 , 1320 , 1322 are in fluid connection with the fluid line and can be used to determine sensor data of the fluid entering the mixing chamber (not shown in this figure). Thus, in the exemplary embodiment, the sensor elements 1318 , 1320 , 1322 are used to collect data regarding fluid being pumped into the mixing chamber. Referring back to FIG. 12B , sensor elements 1308 , 1310 , 1312 are used to collect data regarding fluid being pumped from the mixing chamber and to the fluid outlet.
  • no sensors are or only one set, or only one type of sensor element (i.e., either temperature or conductivity sensor element) is used. Any type of sensor may be used and additionally, any embodiment of a temperature, a conductivity sensor element or a combined temperature/conductivity sensor element.
  • the exemplary embodiment is one cassette embodiment that incorporates the exemplary fluid flow-path schematic shown in FIG. 8 .
  • the cassette incorporate many of the same features of the exemplary embodiment, but in a different structural design and with slightly different flow paths.
  • One of these alternate embodiments is the embodiment shown in FIGS. 16A-20B .
  • FIGS. 16A-16C views of an alternate embodiment of the top plate 1600 are shown.
  • the features of the top plate 1600 are alternate embodiments of corresponding features in the exemplary embodiment.
  • This alternate embodiment includes two mixing chambers 1622 , 1624 and three metering pumps.
  • this embodiment represents the flexibility in the cassette design.
  • the cassette can mix any number of fluids, as well, can meter them separately or together.
  • FIG. 9 shows a fluid flow-path schematic of the cassette shown in FIGS. 16A-20B .
  • FIGS. 17A-17C views of an alternate embodiment of the midplate 1700 are shown.
  • FIGS. 18A-18C show views of an alternate embodiment of the bottom plate 1800 .
  • FIGS. 19C-19D show exploded views of the cassette 1900 where the pod pump membranes 1910 , valve membranes 1914 and metering pump membranes 1912 are shown.
  • the three metering pumps 1616 , 1618 , 1620 can be seen as well as the respective membranes 1912 .
  • three fluids can be metered and controlled volumes of each can be mixed together in the mixing chambers 1622 , 1624 .
  • FIGS. 20A and 20B show a cross sectional view of the assembled cassette 1900 .
  • the cassette may be used to pump any type of fluid from any source to any location.
  • the types of fluid include nutritive, nonnutritive, inorganic chemicals, organic chemicals, bodily fluids or any other type of fluid.
  • fluid in some embodiments includes a gas, thus, in some embodiments; the cassette is used to pump a gas.
  • the cassette serves to pump and direct the fluid from and to the desired locations.
  • outside pumps pump the fluid into the cassette and the cassette pumps the fluid out.
  • the pod pumps serve to pull the fluid into the cassette and pump the fluid out of the cassette.
  • valves being in different locations or additional valves are alternate embodiments of this cassette.
  • the fluid lines and paths shown in the figures described above are mere examples of fluid lines and paths. Other embodiments may have more, less and/or different fluid paths. In still other embodiments, valves are not present in the cassette.
  • the number of pod pumps described above may also vary depending on the embodiment.
  • the cassette includes one.
  • the cassette includes more than two pod pumps.
  • the pod pumps can be single pumps or work in tandem to provide a more continuous flow. Either or both may be used in various embodiments of the cassette.
  • the various ports are provided to impart particular fluid paths onto the cassette. These ports are not necessarily all used all of the time, instead, the variety of ports provide flexibility of use of the cassette in practice.
  • the pumping cassette can be used in a myriad of applications. However, in one exemplary embodiment, the pumping cassette is used to mix a solution that includes at least two ingredients/compounds. In the exemplary embodiment, three ingredients are mixed. However, in other embodiments, less than three or more than three can be mixed by adding metering pumps, mixing chambers, inlets/outlets, valves and fluid lines. These variations to the cassette design are readily discernable.
  • source ingredient or “sources of ingredients” refers to ingredients other than the fluid pumped into the cassette from the first fluid inlet. These source ingredients are contained in a container, or provided by a source, connected to the cassette.
  • the pumping cassette includes the ability to connect four sources of ingredients to the cassette in addition to the fluid inlet line.
  • the fluid inlet is connected to a water source.
  • the fluid inlet line is connected to a container of a liquid/fluid solution or to another source of fluid/liquid.
  • the four additional sources of ingredients can be four of the same source ingredients, or two of one source ingredient and two of another. Using two of each source ingredient, or four of one source ingredient, pumping and mixing can be done in a continuous manner without having to replace the sources.
  • the number of redundant sources of each ingredient will vary.
  • the source could be a connection to a very large container, a smaller container or a seemingly “endless” source.
  • the number of containers of a source ingredient may vary.
  • One of the fluid paths described above with respect to FIG. 8 includes a path where the pod pumps pump liquid into the cassette and to two of the source ingredients sources or containers.
  • This available functionality of the cassette allows two of the source ingredients to be, at least initially, powder that is constituted with the fluid/liquid from the fluid inlet line.
  • the valves are controlled for a period of time such that continuous pumping of fluid into the fluid inlet and to two source ingredient containers is accomplished.
  • This same valving path can be instituted to the other two source ingredient containers or to one of the other two source ingredient containers in addition to or in lieu of the valving path shown in FIG. 8 .
  • fluid inlet liquid is pumped to only one source ingredient container.
  • fluid is pumped into the fluid inlet and to the source ingredients where the source ingredients are fluid.
  • This embodiment may be used in situations where the fluid inlet fluid is a source ingredient that needs to be mixed with one of the source ingredients prior to pumping.
  • This functionality can be designed into any embodiment of the pumping cassette. However, in some embodiments, this valving path is not included.
  • the metering pumps allow for the pumping of the source ingredients in known volumes. Thus, careful pumping allows for mixing a solution requiring exact concentrations of the various ingredients.
  • a single metering pump could pump multiple source ingredients. However, as an ingredient is pumped, small amounts of that ingredient may be present in the metering fluid line and thus, could contaminate the ingredient and thus, provide for an incorrect assessment of the volume of that second ingredient being pumped. Therefore, in the exemplary embodiment, at least one metering pump is provided for each source ingredient, and thus, a single metering pump is provided for two sources of source ingredients where those two sources contain identical source ingredients.
  • a metering pump for each source ingredient, a metering pump is provided for each source ingredient.
  • additional metering pumps may be included for each additional source ingredient in the pumping cassette.
  • a single metering pump is connected to two source, ingredients because in the exemplary embodiment, these two source ingredients are the same.
  • one metering pump can pump more than one source ingredient and be connected to more than one source ingredient even if they are not the same.
  • Sensors or sensor elements may be included in the fluid lines to determine the concentration, temperature or other characteristic of the fluid being pumped.
  • a sensor could be used to ensure the correct concentration of the source ingredient.
  • sensor elements may be included in the fluid outlet line downstream from the mixing chamber to determine characteristics of the mixed solution prior to the mixed solution exiting the cassette through the fluid outlet. Additionally, a downstream valve can be provided to ensure badly mixed solution is not pumped outside the cassette through the fluid outlet. Discussion of the exemplary embodiment of the sensor elements is included above.
  • the pumping cassette in use is as a mixing cassette as part of a hemodialysis system.
  • the mixing cassette would be used to mix dialysate to feed a dialysate reservoir outside the cassette.
  • the cassette would be connected to two containers of each citric acid and NaCl/bicarbonate.
  • Two metering pumps are present in the cassette, one dedicated to the citric acid and the other to the NaCl/Bicarbonate.
  • one metering pump works with two source ingredient containers.
  • the NaCl/Bicarbonate is a powder and requires the addition of water to create the fluid source ingredient solution.
  • wafer is pumped into the first fluid inlet and into the source containers of NaCl/Bicarbonate.
  • Both pod pumps can pump out of phase to rapidly and continuously provide the necessary water to the source containers of NaCl/Bicarbonate.
  • the citric acid is pumped by a metering pump into a pod pump and then towards the mixing chamber. Water is pumped into the pod pumps as well, resulting in a desired concentration of citric acid. Sensor elements are located upstream from the mixing chamber to determine if the citric acid is in the proper concentration and also, the pod pumps can pump additional water towards the mixing chamber if necessary to achieve the proper concentration.
  • the NaCl/Bicarbonate is pumped by the second metering pump and into the fluid outlet line upstream from the mixing chamber.
  • the citric acid and fluid NaCl/Bicarbonate will enter the mixing chamber.
  • the two source ingredients will then mix and be pumped out the fluid outlet.
  • sensor elements are located downstream from the mixing chamber. These sensor elements can ensure the concentration of the finished solution is proper. Also, in some embodiments, a valve may be located downstream from the fluid outlet. In situations where the sensor data shows the mixing has not been successful or as desired, this valve can block the dialysate from flowing into the reservoir located outside the cassette.
  • addition metering pumps can be includes to remove fluid from the fluid lines. Also, additional pod pumps may be included for additional pumping features. In alternate embodiments of this dialysate mixing process, three metering pumps and two mixing chambers are used (as shown in FIG. 9 ). The citric acid, salt, and bicarbonate are each pumped separately in this embodiment. One mixing chamber is similar to the one described above, and the second mixing chamber is used to mix the salt and bicarbonate prior to flowing to the other mixing chamber, where the mixing between the citric acid, NaCl/Bicarbonate will be accomplished.
  • the fluid lines, valving, metering pumps, mixing chambers, pod pumps and inlet/outlets are modular elements that can be mixed and matched to impart the desired mixing functionality onto the cassette.
  • the valve architecture varies in order to alter the fluid flow-path. Additionally, the sizes of the pod pumps, metering pump and mixing chambers may also vary, as well as the number of valves, pod pumps, metering pumps, sensors, mixing chambers and source ingredient containers connected to the cassette. Although in this embodiment, the valves are volcano valves, in other embodiments, the valves are not volcano valves and in some embodiments are smooth surface valves.
US11/871,787 2007-02-27 2007-10-12 Pumping Cassette Abandoned US20080253911A1 (en)

Priority Applications (69)

Application Number Priority Date Filing Date Title
US11/871,787 US20080253911A1 (en) 2007-02-27 2007-10-12 Pumping Cassette
US12/199,196 US8425471B2 (en) 2007-02-27 2008-08-27 Reagent supply for a hemodialysis system
US12/199,055 US8393690B2 (en) 2007-02-27 2008-08-27 Enclosure for a portable hemodialysis system
US12/199,166 US20090107335A1 (en) 2007-02-27 2008-08-27 Air trap for a medical infusion device
US12/199,077 US9028691B2 (en) 2007-02-27 2008-08-27 Blood circuit assembly for a hemodialysis system
US12/199,068 US8562834B2 (en) 2007-02-27 2008-08-27 Modular assembly for a portable hemodialysis system
CA3075012A CA3075012C (en) 2007-10-12 2008-10-10 Apparatus and methods for hemodialysis
EP17159187.8A EP3228337B1 (en) 2007-10-12 2008-10-10 Connector system for a hemodialysis apparatus
EP08838971.3A EP2197513B1 (en) 2007-10-12 2008-10-10 Blood circuit assembly for a dialysis unit
KR1020147023314A KR101934142B1 (ko) 2007-10-12 2008-10-10 혈액 투석을 위한 장치 및 방법
KR1020107010384A KR101573948B1 (ko) 2007-10-12 2008-10-10 혈액 투석을 위한 장치 및 방법
EP16152813.8A EP3037117B1 (en) 2007-10-12 2008-10-10 Blood line connector
KR1020197035516A KR102196471B1 (ko) 2007-10-12 2008-10-10 혈액 투석을 위한 장치 및 방법
CA3177048A CA3177048A1 (en) 2007-10-12 2008-10-10 Apparatus and methods for hemodialysis
JP2010528896A JP5324587B2 (ja) 2007-10-12 2008-10-10 血液透析用装置および方法
CN200880121285.7A CN101986776B (zh) 2007-10-12 2008-10-10 血液透析装置及方法
MX2010003880A MX340356B (es) 2007-10-12 2008-10-10 Aparato y metodo para hemodialisis.
EP11150584.8A EP2319551B1 (en) 2007-10-12 2008-10-10 Apparatus for hemodialysis
KR1020187037352A KR101973034B1 (ko) 2007-10-12 2008-10-10 혈액 투석을 위한 장치 및 방법
KR1020177002616A KR101769521B1 (ko) 2007-10-12 2008-10-10 혈액 투석을 위한 장치 및 방법
KR1020217043402A KR102413969B1 (ko) 2007-10-12 2008-10-10 혈액 투석을 위한 장치 및 방법
KR1020157011558A KR101657569B1 (ko) 2007-10-12 2008-10-10 혈액 투석을 위한 장치 및 방법
CA2702385A CA2702385C (en) 2007-10-12 2008-10-10 Apparatus and methods for hemodialysis
KR1020187006667A KR101881911B1 (ko) 2007-10-12 2008-10-10 휴대용 혈액 투석 유닛을 수용하는 포위체
BR122019005896A BR122019005896B8 (pt) 2007-10-12 2008-10-10 aparelho e métodos para hemodiálise
CA2971041A CA2971041C (en) 2007-10-12 2008-10-10 Apparatus and methods for hemodialysis
EP21158380.2A EP3848067A1 (en) 2007-10-12 2008-10-10 Apparatus for hemodialysis
KR1020177022556A KR101838530B1 (ko) 2007-10-12 2008-10-10 휴대용 혈액 투석 유닛을 수용하는 포위체
KR1020167024526A KR101702643B1 (ko) 2007-10-12 2008-10-10 혈액 투석을 위한 장치 및 방법
CA2971046A CA2971046C (en) 2007-10-12 2008-10-10 Apparatus and methods for hemodialysis
KR1020147009763A KR101574748B1 (ko) 2007-10-12 2008-10-10 혈액 투석을 위한 장치 및 방법
CN201510086488.9A CN104689393B (zh) 2007-10-12 2008-10-10 血液透析装置及方法
CA2971044A CA2971044C (en) 2007-10-12 2008-10-10 Apparatus and methods for hemodialysis
CA3075014A CA3075014C (en) 2007-10-12 2008-10-10 Apparatus and methods for hemodialysis
KR1020167027838A KR101780620B1 (ko) 2007-10-12 2008-10-10 혈액 투석을 위한 장치 및 방법
PCT/US2008/011663 WO2009051669A1 (en) 2007-10-12 2008-10-10 Apparatus and methods for hemodialysis
KR1020197011369A KR102052692B1 (ko) 2007-10-12 2008-10-10 혈액 투석을 위한 장치 및 방법
EP19155956.6A EP3508231B1 (en) 2007-10-12 2008-10-10 Apparatus for hemodialysis
KR1020217043220A KR20220003166A (ko) 2007-10-12 2008-10-10 혈액 투석을 위한 장치 및 방법
AU2008312005A AU2008312005B2 (en) 2007-10-12 2008-10-10 Apparatus and methods for hemodialysis
KR1020207036973A KR20210000735A (ko) 2007-10-12 2008-10-10 혈액 투석을 위한 장치 및 방법
BRPI0818056A BRPI0818056B8 (pt) 2007-10-12 2008-10-10 aparelho e métodos para hemodiálise
KR1020187020812A KR101921878B1 (ko) 2007-10-12 2008-10-10 휴대용 혈액 투석 유닛을 수용하는 포위체
JP2011243747A JP5270745B2 (ja) 2007-10-12 2011-11-07 血液透析用装置および方法
US13/352,250 US9649418B2 (en) 2007-02-27 2012-01-17 Pumping cassette
US13/619,266 US8992075B2 (en) 2007-02-27 2012-09-14 Sensor apparatus systems, devices and methods
US13/790,974 US9539379B2 (en) 2007-02-27 2013-03-08 Enclosure for a portable hemodialysis system
JP2013149599A JP5749767B2 (ja) 2007-10-12 2013-07-18 血液透析装置における３叉試薬供給コネクタシステム
US14/059,806 US10441697B2 (en) 2007-02-27 2013-10-22 Modular assembly for a portable hemodialysis system
US14/132,838 US9597442B2 (en) 2007-02-27 2013-12-18 Air trap for a medical infusion device
US14/672,764 US9535021B2 (en) 2007-02-27 2015-03-30 Sensor apparatus systems, devices and methods
US14/692,801 US9987407B2 (en) 2007-02-27 2015-04-22 Blood circuit assembly for a hemodialysis system
JP2015099430A JP5782207B2 (ja) 2007-10-12 2015-05-14 携帯型血液透析部用のモジュール式アセンブリシステム
JP2015142465A JP5824183B2 (ja) 2007-10-12 2015-07-16 携帯型血液透析部を収容するための筐体
JP2015200155A JP6027206B2 (ja) 2007-10-12 2015-10-08 携帯型血液透析部を収容するための筐体
JP2016201759A JP6389219B2 (ja) 2007-10-12 2016-10-13 ３叉試薬供給コネクタ及び３叉消毒コネクタ
US15/399,895 US9795728B2 (en) 2007-02-27 2017-01-06 Enclosure for a portable hemodialysis system
US15/463,888 US10098998B2 (en) 2007-02-27 2017-03-20 Air trap for a medical infusion device
US15/789,916 US10780210B2 (en) 2007-02-27 2017-10-20 Enclosure for a portable hemodialysis system
US15/996,247 US10500327B2 (en) 2007-02-27 2018-06-01 Blood circuit assembly for a hemodialysis system
JP2018153084A JP6703054B2 (ja) 2007-10-12 2018-08-16 透析ユニット内の血液流から空気または他の未溶解ガスを除去する方法および透析システム
US16/594,181 US11311656B2 (en) 2007-02-27 2019-10-07 Modular assembly for a portable hemodialysis system
US16/707,839 US11110212B2 (en) 2007-02-27 2019-12-09 Blood circuit assembly for a hemodialysis system
JP2020081788A JP6955607B2 (ja) 2007-10-12 2020-05-07 透析ユニット内の血液流から空気または他の未溶解ガスを除去する方法および透析システム
US17/466,806 US11752244B2 (en) 2007-02-27 2021-09-03 Blood circuit assembly for a hemodialysis system
JP2021162808A JP7410104B2 (ja) 2007-10-12 2021-10-01 透析ユニット内の血液流から空気または他の未溶解ガスを除去する方法および透析システム
US17/718,533 US20220241479A1 (en) 2007-02-27 2022-04-12 Modular assembly for a portable hemodialysis system
US18/358,840 US20230364312A1 (en) 2007-02-27 2023-07-25 Blood circuit assembly for a hemodialysis system
JP2023215656A JP2024023777A (ja) 2007-10-12 2023-12-21 透析ユニット内の血液流から空気または他の未溶解ガスを除去する方法および透析システム

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US90402407P 2007-02-27 2007-02-27
US92131407P 2007-04-02 2007-04-02
US11/871,787 US20080253911A1 (en) 2007-02-27 2007-10-12 Pumping Cassette

Related Parent Applications (2)

Application Number Title Priority Date Filing Date
US11/871,793 Continuation-In-Part US8888470B2 (en) 2007-02-27 2007-10-12 Pumping cassette
US11/871,712 Continuation-In-Part US8317492B2 (en) 2007-02-27 2007-10-12 Pumping cassette

Related Child Applications (7)

Application Number Title Priority Date Filing Date
US11/871,793 Continuation-In-Part US8888470B2 (en) 2007-02-27 2007-10-12 Pumping cassette
US11/871,712 Continuation-In-Part US8317492B2 (en) 2007-02-27 2007-10-12 Pumping cassette
US12/199,068 Continuation-In-Part US8562834B2 (en) 2007-02-27 2008-08-27 Modular assembly for a portable hemodialysis system
US12/199,077 Continuation-In-Part US9028691B2 (en) 2007-02-27 2008-08-27 Blood circuit assembly for a hemodialysis system
US12/199,166 Continuation-In-Part US20090107335A1 (en) 2007-02-27 2008-08-27 Air trap for a medical infusion device
US12/199,055 Continuation-In-Part US8393690B2 (en) 2007-02-27 2008-08-27 Enclosure for a portable hemodialysis system
US13/352,250 Division US9649418B2 (en) 2007-02-27 2012-01-17 Pumping cassette

Publications (1)

Publication Number Publication Date
US20080253911A1 true US20080253911A1 (en) 2008-10-16

Family

ID=39714513

Family Applications (21)

Application Number Title Priority Date Filing Date
US11/871,712 Active 2028-10-08 US8317492B2 (en) 2007-02-27 2007-10-12 Pumping cassette
US11/871,828 Active 2029-01-17 US8366655B2 (en) 2007-02-27 2007-10-12 Peritoneal dialysis sensor apparatus systems, devices and methods
US11/871,803 Active 2029-01-03 US7967022B2 (en) 2006-04-14 2007-10-12 Cassette system integrated apparatus
US11/871,680 Active 2030-12-20 US8273049B2 (en) 2006-04-14 2007-10-12 Pumping cassette
US11/871,787 Abandoned US20080253911A1 (en) 2007-02-27 2007-10-12 Pumping Cassette
US11/871,793 Active 2031-12-31 US8888470B2 (en) 2007-02-27 2007-10-12 Pumping cassette
US13/156,282 Active US8459292B2 (en) 2006-04-14 2011-06-08 Cassette system integrated apparatus
US13/352,250 Active 2030-02-18 US9649418B2 (en) 2007-02-27 2012-01-17 Pumping cassette
US13/624,460 Active 2028-11-16 US9272082B2 (en) 2006-04-14 2012-09-21 Pumping cassette
US13/684,995 Active US8926294B2 (en) 2007-02-27 2012-11-26 Pumping cassette
US13/914,138 Active US8985133B2 (en) 2006-04-14 2013-06-10 Cassette system integrated apparatus
US14/589,829 Active 2028-09-30 US9700660B2 (en) 2007-02-27 2015-01-05 Pumping cassette
US14/666,059 Active US9951768B2 (en) 2006-04-14 2015-03-23 Cassette system integrated apparatus
US15/056,701 Active US9550018B2 (en) 2006-04-14 2016-02-29 Pumping cassette
US15/413,369 Active 2027-11-03 US10415559B2 (en) 2006-04-14 2017-01-23 Pumping cassette
US15/635,780 Active US10077766B2 (en) 2007-02-27 2017-06-28 Pumping cassette
US15/960,426 Abandoned US20180372084A1 (en) 2007-02-27 2018-04-23 Cassette system integrated apparatus
US16/133,279 Active US10851769B2 (en) 2007-02-27 2018-09-17 Pumping cassette
US16/573,676 Active 2028-07-11 US11419965B2 (en) 2006-04-14 2019-09-17 Pumping cassette
US17/107,495 Active 2028-10-20 US11779691B2 (en) 2007-02-27 2020-11-30 Pumping cassette
US18/460,492 Pending US20240066197A1 (en) 2007-02-27 2023-09-01 Pumping cassette

Family Applications Before (4)

Application Number Title Priority Date Filing Date
US11/871,712 Active 2028-10-08 US8317492B2 (en) 2007-02-27 2007-10-12 Pumping cassette
US11/871,828 Active 2029-01-17 US8366655B2 (en) 2007-02-27 2007-10-12 Peritoneal dialysis sensor apparatus systems, devices and methods
US11/871,803 Active 2029-01-03 US7967022B2 (en) 2006-04-14 2007-10-12 Cassette system integrated apparatus
US11/871,680 Active 2030-12-20 US8273049B2 (en) 2006-04-14 2007-10-12 Pumping cassette

Family Applications After (16)

Application Number Title Priority Date Filing Date
US11/871,793 Active 2031-12-31 US8888470B2 (en) 2007-02-27 2007-10-12 Pumping cassette
US13/156,282 Active US8459292B2 (en) 2006-04-14 2011-06-08 Cassette system integrated apparatus
US13/352,250 Active 2030-02-18 US9649418B2 (en) 2007-02-27 2012-01-17 Pumping cassette
US13/624,460 Active 2028-11-16 US9272082B2 (en) 2006-04-14 2012-09-21 Pumping cassette
US13/684,995 Active US8926294B2 (en) 2007-02-27 2012-11-26 Pumping cassette
US13/914,138 Active US8985133B2 (en) 2006-04-14 2013-06-10 Cassette system integrated apparatus
US14/589,829 Active 2028-09-30 US9700660B2 (en) 2007-02-27 2015-01-05 Pumping cassette
US14/666,059 Active US9951768B2 (en) 2006-04-14 2015-03-23 Cassette system integrated apparatus
US15/056,701 Active US9550018B2 (en) 2006-04-14 2016-02-29 Pumping cassette
US15/413,369 Active 2027-11-03 US10415559B2 (en) 2006-04-14 2017-01-23 Pumping cassette
US15/635,780 Active US10077766B2 (en) 2007-02-27 2017-06-28 Pumping cassette
US15/960,426 Abandoned US20180372084A1 (en) 2007-02-27 2018-04-23 Cassette system integrated apparatus
US16/133,279 Active US10851769B2 (en) 2007-02-27 2018-09-17 Pumping cassette
US16/573,676 Active 2028-07-11 US11419965B2 (en) 2006-04-14 2019-09-17 Pumping cassette
US17/107,495 Active 2028-10-20 US11779691B2 (en) 2007-02-27 2020-11-30 Pumping cassette
US18/460,492 Pending US20240066197A1 (en) 2007-02-27 2023-09-01 Pumping cassette

Country Status (10)

Country Link
US (21) US8317492B2 (es)
EP (11) EP3189863B1 (es)
JP (25) JP5174044B2 (es)
KR (17) KR102410172B1 (es)
CN (4) CN104174077B (es)
AU (7) AU2008221455B2 (es)
BR (3) BRPI0808038B8 (es)
CA (10) CA2681914C (es)
MX (10) MX359478B (es)
WO (2) WO2008106440A1 (es)

Cited By (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100327849A1 (en) * 2006-04-14 2010-12-30 Deka Products Limited Partnership Sensor apparatus systems, devices and methods
US20110071465A1 (en) * 2008-01-23 2011-03-24 Deka Research & Development Fluid volume determination for medical treatment system
US7967022B2 (en) 2007-02-27 2011-06-28 Deka Products Limited Partnership Cassette system integrated apparatus
US8042563B2 (en) 2007-02-27 2011-10-25 Deka Products Limited Partnership Cassette system integrated apparatus
US8114276B2 (en) 2007-10-24 2012-02-14 Baxter International Inc. Personal hemodialysis system
US8246826B2 (en) 2007-02-27 2012-08-21 Deka Products Limited Partnership Hemodialysis systems and methods
US8292594B2 (en) 2006-04-14 2012-10-23 Deka Products Limited Partnership Fluid pumping systems, devices and methods
US8357298B2 (en) 2007-02-27 2013-01-22 Deka Products Limited Partnership Hemodialysis systems and methods
US8393690B2 (en) 2007-02-27 2013-03-12 Deka Products Limited Partnership Enclosure for a portable hemodialysis system
US8409441B2 (en) 2007-02-27 2013-04-02 Deka Products Limited Partnership Blood treatment systems and methods
US8425471B2 (en) 2007-02-27 2013-04-23 Deka Products Limited Partnership Reagent supply for a hemodialysis system
US8491184B2 (en) 2007-02-27 2013-07-23 Deka Products Limited Partnership Sensor apparatus systems, devices and methods
US8562834B2 (en) 2007-02-27 2013-10-22 Deka Products Limited Partnership Modular assembly for a portable hemodialysis system
US8708950B2 (en) 2010-07-07 2014-04-29 Deka Products Limited Partnership Medical treatment system and methods using a plurality of fluid lines
US8771508B2 (en) 2008-08-27 2014-07-08 Deka Products Limited Partnership Dialyzer cartridge mounting arrangement for a hemodialysis system
US8863772B2 (en) 2008-08-27 2014-10-21 Deka Products Limited Partnership Occluder for a medical infusion system
US9028691B2 (en) 2007-02-27 2015-05-12 Deka Products Limited Partnership Blood circuit assembly for a hemodialysis system
US9078971B2 (en) 2008-01-23 2015-07-14 Deka Products Limited Partnership Medical treatment system and methods using a plurality of fluid lines
US9364655B2 (en) 2012-05-24 2016-06-14 Deka Products Limited Partnership Flexible tubing occlusion assembly
US9517295B2 (en) 2007-02-27 2016-12-13 Deka Products Limited Partnership Blood treatment systems and methods
US9597442B2 (en) 2007-02-27 2017-03-21 Deka Products Limited Partnership Air trap for a medical infusion device
US9724458B2 (en) 2011-05-24 2017-08-08 Deka Products Limited Partnership Hemodialysis system
US9861732B2 (en) 2011-11-04 2018-01-09 Deka Products Limited Partnership Medical treatment system and methods using a plurality of fluid lines
US9861733B2 (en) 2012-03-23 2018-01-09 Nxstage Medical Inc. Peritoneal dialysis systems, devices, and methods
US9907897B2 (en) 2011-03-23 2018-03-06 Nxstage Medical, Inc. Peritoneal dialysis systems, devices, and methods
US9999717B2 (en) 2011-05-24 2018-06-19 Deka Products Limited Partnership Systems and methods for detecting vascular access disconnection
US10201650B2 (en) 2009-10-30 2019-02-12 Deka Products Limited Partnership Apparatus and method for detecting disconnection of an intravascular access device
US10463774B2 (en) 2007-02-27 2019-11-05 Deka Products Limited Partnership Control systems and methods for blood or fluid handling medical devices
US10537671B2 (en) 2006-04-14 2020-01-21 Deka Products Limited Partnership Automated control mechanisms in a hemodialysis apparatus
US11207454B2 (en) 2018-02-28 2021-12-28 Nxstage Medical, Inc. Fluid preparation and treatment devices methods and systems
US11371498B2 (en) 2018-03-30 2022-06-28 Deka Products Limited Partnership Liquid pumping cassettes and associated pressure distribution manifold and related methods
US11939566B2 (en) 2016-11-07 2024-03-26 Deka Products Limited Partnership System and method for creating tissue

Families Citing this family (192)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6877713B1 (en) 1999-07-20 2005-04-12 Deka Products Limited Partnership Tube occluder and method for occluding collapsible tubes
AU2003230862A1 (en) 2002-04-11 2003-10-27 Deka Products Limited Partnership System and method for delivering a target volume of fluid
DE10224750A1 (de) 2002-06-04 2003-12-24 Fresenius Medical Care De Gmbh Vorrichtung zur Behandlung einer medizinischen Flüssigkeit
US8038639B2 (en) 2004-11-04 2011-10-18 Baxter International Inc. Medical fluid system with flexible sheeting disposable unit
US20060217771A1 (en) 2005-02-07 2006-09-28 Medtronic, Inc. Potassium monitoring
US7935074B2 (en) 2005-02-28 2011-05-03 Fresenius Medical Care Holdings, Inc. Cassette system for peritoneal dialysis machine
US8197231B2 (en) 2005-07-13 2012-06-12 Purity Solutions Llc Diaphragm pump and related methods
US20140199193A1 (en) 2007-02-27 2014-07-17 Deka Products Limited Partnership Blood treatment systems and methods
US8287724B2 (en) * 2007-07-05 2012-10-16 Baxter International Inc. Dialysis fluid measurement systems using conductive contacts
US20090007642A1 (en) * 2007-07-05 2009-01-08 Baxter International Inc. Dialysis fluid measurement method and apparatus using conductive contacts
WO2009028963A2 (en) * 2007-08-30 2009-03-05 Fisher & Paykel Appliances Limited Variable pressure water delivery system
US8057437B2 (en) * 2007-08-31 2011-11-15 Hospira, Inc. Radially sealing vavle for an infusion set
US9199022B2 (en) 2008-09-12 2015-12-01 Fresenius Medical Care Holdings, Inc. Modular reservoir assembly for a hemodialysis and hemofiltration system
US9308307B2 (en) * 2007-09-13 2016-04-12 Fresenius Medical Care Holdings, Inc. Manifold diaphragms
US8105487B2 (en) 2007-09-25 2012-01-31 Fresenius Medical Care Holdings, Inc. Manifolds for use in conducting dialysis
US8240636B2 (en) 2009-01-12 2012-08-14 Fresenius Medical Care Holdings, Inc. Valve system
US9358331B2 (en) 2007-09-13 2016-06-07 Fresenius Medical Care Holdings, Inc. Portable dialysis machine with improved reservoir heating system
US8597505B2 (en) 2007-09-13 2013-12-03 Fresenius Medical Care Holdings, Inc. Portable dialysis machine
CA2702385C (en) * 2007-10-12 2017-07-18 Deka Products Limited Partnership Apparatus and methods for hemodialysis
EP2246080B1 (en) * 2007-10-12 2016-02-10 DEKA Products Limited Partnership An extracorporeal blood flow system
US20100056975A1 (en) * 2008-08-27 2010-03-04 Deka Products Limited Partnership Blood line connector for a medical infusion device
CA2960103C (en) 2007-11-29 2020-03-10 Fredenius Medical Care Holdings, Inc. System and method for conducting hemodialysis and hemofiltration
US11738130B2 (en) 2008-01-23 2023-08-29 Deka Products Limited Partnership Fluid line autoconnect apparatus and methods for medical treatment system
US11833281B2 (en) 2008-01-23 2023-12-05 Deka Products Limited Partnership Pump cassette and methods for use in medical treatment system using a plurality of fluid lines
US10195330B2 (en) 2008-01-23 2019-02-05 Deka Products Limited Partnership Medical treatment system and methods using a plurality of fluid lines
US10201647B2 (en) 2008-01-23 2019-02-12 Deka Products Limited Partnership Medical treatment system and methods using a plurality of fluid lines
DE102008011828A1 (de) * 2008-02-29 2009-09-10 Fresenius Medical Care Deutschland Gmbh Verfahren und Vorrichtung zum Erwärmen von Lösungen, vorzugsweise Dialyselösungen
US8057679B2 (en) * 2008-07-09 2011-11-15 Baxter International Inc. Dialysis system having trending and alert generation
JP5654466B2 (ja) * 2008-08-27 2015-01-14 デカ・プロダクツ・リミテッド・パートナーシップ 透析システムの作動方法
EP2334412B1 (en) 2008-10-07 2019-08-21 Fresenius Medical Care Holdings, Inc. Priming system and method for dialysis systems
EP2342003B1 (en) * 2008-10-30 2018-09-26 Fresenius Medical Care Holdings, Inc. Modular, portable dialysis system
DE102009000802A1 (de) * 2009-02-12 2010-08-19 Robert Bosch Gmbh Überdruckventil für einen Verpackungsbehälter
US8192401B2 (en) 2009-03-20 2012-06-05 Fresenius Medical Care Holdings, Inc. Medical fluid pump systems and related components and methods
WO2011008858A1 (en) 2009-07-15 2011-01-20 Fresenius Medical Care Holdings, Inc. Medical fluid cassettes and related systems and methods
CA2921304C (en) 2009-07-30 2018-06-05 Tandem Diabetes Care, Inc. Infusion pump system with disposable cartridge having pressure venting and pressure feedback
US8720913B2 (en) 2009-08-11 2014-05-13 Fresenius Medical Care Holdings, Inc. Portable peritoneal dialysis carts and related systems
US9399091B2 (en) 2009-09-30 2016-07-26 Medtronic, Inc. System and method to regulate ultrafiltration
WO2011045167A1 (en) 2009-10-15 2011-04-21 Gambro Lundia Ab Membrane pump system
JP5837823B2 (ja) * 2009-10-23 2015-12-24 旭化成メディカル株式会社 血液透析装置、血液透析装置の作動方法及び水分除去システム
US8460228B2 (en) * 2009-10-27 2013-06-11 Nxstage Medical Inc. Methods, devices, and systems for parallel control of infusion device
DE102009060330A1 (de) * 2009-12-23 2011-06-30 Fresenius Medical Care Deutschland GmbH, 61352 Dialysemaschine, insbesondere Peritonealdialysemaschine
EP2759311B1 (en) * 2009-12-24 2017-02-22 VR Medical Technology Co., Ltd. Automated peritoneal dialysis cycler and methods of use
DE102010005745A1 (de) * 2010-01-26 2011-07-28 Fresenius Medical Care Deutschland GmbH, 61352 Dialysemaschine
JP5569014B2 (ja) * 2010-02-03 2014-08-13 セイコーエプソン株式会社 流体輸送装置
JP5908667B2 (ja) * 2010-02-25 2016-04-26 ザマ・ジャパン株式会社 回転絞り弁式気化器における弁軸の防塵シール構造
DE102010003642A1 (de) 2010-03-15 2011-09-15 Fresenius Medical Care Deutschland Gmbh Kassette mit einem Sensor zur Bestimmung der Differenz eines ersten und eines zweiten Flüssigkeitsstroms
NZ602489A (en) * 2010-03-19 2014-10-31 Ambrosios Kambouris Valve assembly
US9132219B2 (en) 2010-04-16 2015-09-15 Baxter International Inc. Therapy prediction and optimization of serum potassium for renal failure blood therapy, especially home hemodialysis
US8845570B2 (en) 2010-04-16 2014-09-30 Baxter International Inc. Therapy prediction and optimization for renal failure blood therapy, especially home hemodialysis
AU2011239488B2 (en) 2010-04-16 2015-05-21 Baxter Healthcare S.A. Therapy prediction and optimization for renal failure blood therapy, especially home hemodialysis
WO2012012758A2 (en) * 2010-07-23 2012-01-26 Medela Holding Ag Pumping device, as for enteral feeding assembly
JP2012075574A (ja) * 2010-09-30 2012-04-19 Terumo Corp 自動腹膜透析装置
DE102010053973A1 (de) 2010-12-09 2012-06-14 Fresenius Medical Care Deutschland Gmbh Medizinisches Gerät mit einer Heizung
CN102553040B (zh) * 2010-12-17 2014-07-02 陈庆堂 滤出药粉吸入器
WO2012087798A2 (en) 2010-12-20 2012-06-28 Fresenius Medical Care Holdings, Inc. Medical fluid cassettes and related systems and methods
US9624915B2 (en) 2011-03-09 2017-04-18 Fresenius Medical Care Holdings, Inc. Medical fluid delivery sets and related systems and methods
MX341315B (es) 2011-04-21 2016-08-12 Fresenius Medical Care Holdings Inc Sistemas de bombeo de fluido medico y dispositivos y metodos relacionados.
US9750862B2 (en) 2011-04-29 2017-09-05 Medtronic, Inc. Adaptive system for blood fluid removal
US9456755B2 (en) 2011-04-29 2016-10-04 Medtronic, Inc. Method and device to monitor patients with kidney disease
US9848778B2 (en) 2011-04-29 2017-12-26 Medtronic, Inc. Method and device to monitor patients with kidney disease
DE102011108784A1 (de) * 2011-07-29 2013-01-31 Fresenius Medical Care Deutschland Gmbh Verfahren sowie Vorrichtungen zum Überprüfen wenigstens einer Funktion einer medizinischen Funktionseinrichtung
EP2739325B1 (en) 2011-08-02 2017-10-04 Medtronic, Inc. Hemodialysis system having a flow path with a controlled compliant volume
US10857277B2 (en) 2011-08-16 2020-12-08 Medtronic, Inc. Modular hemodialysis system
US9186449B2 (en) 2011-11-01 2015-11-17 Fresenius Medical Care Holdings, Inc. Dialysis machine support assemblies and related systems and methods
WO2013103906A1 (en) 2012-01-04 2013-07-11 Medtronic, Inc. Multi-staged filtration system for blood fluid removal
AU2013232848B2 (en) * 2012-03-15 2018-03-22 Fisher & Paykel Healthcare Limited Respiratory gas humidification system
DE202012003948U1 (de) * 2012-04-20 2012-05-15 Bürkert Werke GmbH Pneumatische Dosiereinheit sowie pneumatische Dosiersystem
US9180242B2 (en) 2012-05-17 2015-11-10 Tandem Diabetes Care, Inc. Methods and devices for multiple fluid transfer
US9555186B2 (en) 2012-06-05 2017-01-31 Tandem Diabetes Care, Inc. Infusion pump system with disposable cartridge having pressure venting and pressure feedback
US9610392B2 (en) 2012-06-08 2017-04-04 Fresenius Medical Care Holdings, Inc. Medical fluid cassettes and related systems and methods
US9500188B2 (en) 2012-06-11 2016-11-22 Fresenius Medical Care Holdings, Inc. Medical fluid cassettes and related systems and methods
SG11201501278PA (en) * 2012-10-31 2015-03-30 Pluristem Ltd Method and device for thawing biological material
US10905816B2 (en) 2012-12-10 2021-02-02 Medtronic, Inc. Sodium management system for hemodialysis
AU2013201553B1 (en) * 2012-12-13 2014-05-29 Gambro Lundia Ab Cassette for pumping a treatment solution through a dialyzer
WO2014100732A1 (en) 2012-12-21 2014-06-26 Micronics, Inc. Fluidic circuits and related manufacturing methods
US9201036B2 (en) 2012-12-21 2015-12-01 Fresenius Medical Care Holdings, Inc. Method and system of monitoring electrolyte levels and composition using capacitance or induction
EP2935559B1 (en) 2012-12-21 2020-09-16 PerkinElmer Health Sciences, Inc. Fluorescence detection system
US10518262B2 (en) 2012-12-21 2019-12-31 Perkinelmer Health Sciences, Inc. Low elasticity films for microfluidic use
US9157786B2 (en) 2012-12-24 2015-10-13 Fresenius Medical Care Holdings, Inc. Load suspension and weighing system for a dialysis machine reservoir
US9707328B2 (en) 2013-01-09 2017-07-18 Medtronic, Inc. Sorbent cartridge to measure solute concentrations
US9713666B2 (en) 2013-01-09 2017-07-25 Medtronic, Inc. Recirculating dialysate fluid circuit for blood measurement
US11565029B2 (en) 2013-01-09 2023-01-31 Medtronic, Inc. Sorbent cartridge with electrodes
US11154648B2 (en) 2013-01-09 2021-10-26 Medtronic, Inc. Fluid circuits for sorbent cartridge with sensors
US10543052B2 (en) 2013-02-01 2020-01-28 Medtronic, Inc. Portable dialysis cabinet
US10010663B2 (en) 2013-02-01 2018-07-03 Medtronic, Inc. Fluid circuit for delivery of renal replacement therapies
US9623164B2 (en) 2013-02-01 2017-04-18 Medtronic, Inc. Systems and methods for multifunctional volumetric fluid control
US10850016B2 (en) 2013-02-01 2020-12-01 Medtronic, Inc. Modular fluid therapy system having jumpered flow paths and systems and methods for cleaning and disinfection
US9526822B2 (en) 2013-02-01 2016-12-27 Medtronic, Inc. Sodium and buffer source cartridges for use in a modular controlled compliant flow path
US9144640B2 (en) 2013-02-02 2015-09-29 Medtronic, Inc. Sorbent cartridge configurations for improved dialysate regeneration
US9827361B2 (en) 2013-02-02 2017-11-28 Medtronic, Inc. pH buffer measurement system for hemodialysis systems
DE102013102397B4 (de) * 2013-03-11 2020-01-02 Bürkert Werke GmbH Dosiersystem, Gehäuseteil für eine Dosiereinheit und Dosiereinheit
US9188490B2 (en) * 2013-03-12 2015-11-17 Rosemount Inc. Thermowell insert
US9561323B2 (en) 2013-03-14 2017-02-07 Fresenius Medical Care Holdings, Inc. Medical fluid cassette leak detection methods and devices
US9173998B2 (en) 2013-03-14 2015-11-03 Tandem Diabetes Care, Inc. System and method for detecting occlusions in an infusion pump
US9180243B2 (en) 2013-03-15 2015-11-10 Tandem Diabetes Care, Inc. Detection of infusion pump conditions
US9421329B2 (en) 2013-03-15 2016-08-23 Tandem Diabetes Care, Inc. Infusion device occlusion detection system
WO2014144909A2 (en) 2013-03-15 2014-09-18 Deka Products Limited Partnership Blood treatment systems and methods
GB201305758D0 (en) * 2013-03-28 2013-05-15 Quanta Fluid Solutions Ltd Blood Pump
JP6484222B2 (ja) 2013-05-07 2019-03-13 マイクロニクス， インコーポレイテッド 核酸の調製および分析のためのデバイス
US10386377B2 (en) 2013-05-07 2019-08-20 Micronics, Inc. Microfluidic devices and methods for performing serum separation and blood cross-matching
CN105189750B (zh) 2013-05-07 2020-07-28 珀金埃尔默健康科学有限公司 使用粘土矿物和碱性溶液制备含核酸样品的方法
US10350352B2 (en) 2013-05-23 2019-07-16 Turnpoint Medical Devices, Inc. Pneumatically coupled fluid control system and process with air detection and elimination
DE102013013415A1 (de) * 2013-08-09 2015-02-12 Fresenius Medical Care Deutschland Gmbh Kassettenmodul
DE102013013414B3 (de) 2013-08-09 2015-01-29 Fresenius Medical Care Deutschland Gmbh Kassettenmodul
JP6477704B2 (ja) 2013-08-16 2019-03-06 バクスター・インターナショナル・インコーポレイテッドＢａｘｔｅｒ Ｉｎｔｅｒｎａｔｉｏｎａｌ Ｉｎｃｏｒｐ０Ｒａｔｅｄ 腎不全血液療法、特に在宅血液透析のための血清カリウムの療法予測及び最適化
US10117985B2 (en) 2013-08-21 2018-11-06 Fresenius Medical Care Holdings, Inc. Determining a volume of medical fluid pumped into or out of a medical fluid cassette
EP3102107A4 (en) 2013-11-04 2018-02-07 Medtronic, Inc. Method and device to manage fluid volumes in the body
US9354640B2 (en) 2013-11-11 2016-05-31 Fresenius Medical Care Holdings, Inc. Smart actuator for valve
US20150133861A1 (en) 2013-11-11 2015-05-14 Kevin P. McLennan Thermal management system and method for medical devices
US20150131022A1 (en) * 2013-11-13 2015-05-14 Shenzhen China Star Optoelectronics Technology Co. Ltd. Multiple display monitor
US10537875B2 (en) 2013-11-26 2020-01-21 Medtronic, Inc. Precision recharging of sorbent materials using patient and session data
US9884145B2 (en) 2013-11-26 2018-02-06 Medtronic, Inc. Parallel modules for in-line recharging of sorbents using alternate duty cycles
US10595775B2 (en) 2013-11-27 2020-03-24 Medtronic, Inc. Precision dialysis monitoring and synchronization system
US8960010B1 (en) 2013-12-23 2015-02-24 Fresenius Medical Care Holdings, Inc. Automatic detection and adjustment of a pressure pod diaphragm
NL1040590C2 (nl) * 2014-01-07 2015-07-08 Alcmair Partners B V Leidingsysteem voor een inrichting voor het beademen van patiënten.
DE102014103507A1 (de) * 2014-03-14 2015-09-17 Fresenius Medical Care Deutschland Gmbh Medizinische Funktionsvorrichtung mit einem Ventilsitz für ein remanentes Rückschlagventil
DK2921705T3 (en) * 2014-03-20 2019-01-07 Annovi Reverberi Spa Diaphragm plate group for diaphragm pumps
EP2999497A4 (en) * 2014-04-22 2016-10-26 Fresenius Med Care Hldg Inc COLLECTOR DIAPHRAGMS
EP3698826A1 (en) 2014-06-05 2020-08-26 DEKA Products Limited Partnership System for calculating a change in fluid volume in a pumping chamber
US10172991B2 (en) 2014-06-24 2019-01-08 Medtronic, Inc. Modular dialysate regeneration assembly
EP3160534A4 (en) 2014-06-24 2018-03-07 Medtronic Inc. Stacked sorbent assembly
US10143795B2 (en) 2014-08-18 2018-12-04 Icu Medical, Inc. Intravenous pole integrated power, control, and communication system and method for an infusion pump
US10478544B2 (en) 2014-09-25 2019-11-19 Nxstage Medical, Inc. Medicament preparation and treatment devices, methods, and systems
US9757505B2 (en) * 2014-09-26 2017-09-12 Fresenius Medical Care Holdings, Inc. Pressure output device for extracorporeal hemodialysis machine
US9903364B2 (en) * 2014-12-05 2018-02-27 Aktiebolaget Skf Backup lubricant supply system
US10098993B2 (en) 2014-12-10 2018-10-16 Medtronic, Inc. Sensing and storage system for fluid balance
US9713665B2 (en) 2014-12-10 2017-07-25 Medtronic, Inc. Degassing system for dialysis
US10874787B2 (en) 2014-12-10 2020-12-29 Medtronic, Inc. Degassing system for dialysis
US9895479B2 (en) 2014-12-10 2018-02-20 Medtronic, Inc. Water management system for use in dialysis
US9931447B2 (en) * 2014-12-16 2018-04-03 Novartis Ag Quick-opening vent valve for phaco fluidics aspiration system
NZ737340A (en) 2015-05-26 2019-06-28 Icu Medical Inc Disposable infusion fluid delivery device for programmable large volume drug delivery
CN116206744A (zh) 2015-06-25 2023-06-02 甘布罗伦迪亚股份公司 具有分布式数据库的医疗装置系统和方法
CA2990670C (en) 2015-07-02 2022-08-16 Northgate Technologies Inc. Gas recirculation system
US10518014B2 (en) * 2015-10-30 2019-12-31 Nxstage Medical, Inc. Treatment fluid devices methods and systems
WO2017078965A1 (en) 2015-11-06 2017-05-11 Medtronic, Inc Dialysis prescription optimization for decreased arrhythmias
EP3708835A1 (en) 2015-11-10 2020-09-16 Repligen Corporation Disposable alternating tangential flow filtration units
DE102015016670A1 (de) * 2015-12-21 2017-06-22 Fresenius Medical Care Deutschland Gmbh Blutbehandlungsgerät umfassend eine Dosierleitung mit einer Membranpumpe und einem Ventil und Verfahren zur Dosierung
US10617809B2 (en) 2015-12-29 2020-04-14 Fresenius Medical Care Holdings, Inc. Electrical sensor for fluids
US10406269B2 (en) 2015-12-29 2019-09-10 Fresenius Medical Care Holdings, Inc. Electrical sensor for fluids
US10578092B2 (en) 2016-03-18 2020-03-03 Deka Products Limited Partnership Pressure control gaskets for operating pump cassette membranes
US10874790B2 (en) 2016-08-10 2020-12-29 Medtronic, Inc. Peritoneal dialysis intracycle osmotic agent adjustment
US20180021500A1 (en) * 2016-04-04 2018-01-25 Medtronic, Inc. Peritoneal dialysate temperature regulation system
US10994064B2 (en) 2016-08-10 2021-05-04 Medtronic, Inc. Peritoneal dialysate flow path sensing
US10126176B2 (en) 2016-04-21 2018-11-13 Thermo Fisher Scientific (Asheville) Llc Sensor container for mounting a temperature sensor, and associated refrigerator
EP3474807A4 (en) * 2016-06-22 2019-07-17 Mego Afek Ac Ltd. VARIABLE PRESSURE VALVE WITH MULTIPLE CHAMBERS
DE102016009174B3 (de) * 2016-07-29 2017-11-02 W. O. M. World of Medicine GmbH Schlauchkassette für eine peristaltische Pumpe mit elastischen Schenkeln
US20190162177A1 (en) * 2016-08-01 2019-05-30 Walbro Llc Fluid driven diaphragm pump
CN109863308B (zh) 2016-08-10 2020-09-15 可克斯塔特国际股份有限公司 模块化多级泵组件
DE102016010222A1 (de) * 2016-08-20 2018-02-22 Fresenius Medical Care Deutschland Gmbh Vorrichtung und Verfahren zur Bereitstellung von Dialysierflüssigkeit und Dialysevorrichtung
WO2018041760A1 (en) * 2016-09-02 2018-03-08 Gambro Lundia Ab Apparatus for providing automated peritoneal dialysis
US11013843B2 (en) 2016-09-09 2021-05-25 Medtronic, Inc. Peritoneal dialysis fluid testing system
US10981148B2 (en) 2016-11-29 2021-04-20 Medtronic, Inc. Zirconium oxide module conditioning
EP3559951B1 (en) 2016-12-21 2022-01-12 Gambro Lundia AB Medical device system including information technology infrastructure having secure cluster domain supporting external domain
DE102016015207A1 (de) * 2016-12-21 2018-06-21 Fresenius Medical Care Deutschland Gmbh Betätigungseinrichtung und Verfahren zum Betreiben einer Betätigungseinrichtung sowie Membranpumpe mit einer Betätigungseinrichtung und einer Membranpumpeneinrichtung und eine Blutbehandlungsvorrichtung mit einer Membranpumpe
US10960381B2 (en) 2017-06-15 2021-03-30 Medtronic, Inc. Zirconium phosphate disinfection recharging and conditioning
US11179516B2 (en) * 2017-06-22 2021-11-23 Baxter International Inc. Systems and methods for incorporating patient pressure into medical fluid delivery
US10729839B2 (en) * 2017-10-03 2020-08-04 Baxter International Inc. Modular medical fluid management assemblies, machines and methods
US10722635B2 (en) * 2017-10-03 2020-07-28 Baxter International Inc. Modular medical fluid management assemblies and associated machines and methods
AU2018345627A1 (en) * 2017-10-03 2020-04-23 Baxter Healthcare Sa Modular medical fluid management assemblies and associated machines and methods
AU2018223035A1 (en) * 2017-10-03 2019-04-18 Medtronic, Inc. Peritoneal dialysate temperature regulation system
EP3717041A4 (en) * 2017-11-29 2021-06-09 Serenno Medical ACTIVE DOUBLE VALVE FLUID PRESSURE ACTUATED POSITIVE DISPLACEMENT PUMP
US11278654B2 (en) 2017-12-07 2022-03-22 Medtronic, Inc. Pneumatic manifold for a dialysis system
USD872260S1 (en) * 2017-12-11 2020-01-07 Deka Products Limited Partnership Reservoir
CA3082240A1 (en) 2017-12-21 2019-06-27 Gambro Lundia Ab Dialysis system having carbon dioxide generation and prime
CN108204836B (zh) * 2017-12-25 2020-04-17 宁波精致诚检测技术服务有限公司 一种便携式可移动的环境监测箱
US11033667B2 (en) 2018-02-02 2021-06-15 Medtronic, Inc. Sorbent manifold for a dialysis system
US11110215B2 (en) 2018-02-23 2021-09-07 Medtronic, Inc. Degasser and vent manifolds for dialysis
EP3566728A1 (en) * 2018-05-09 2019-11-13 ETH Zürich Corrugated membranes
US10969031B2 (en) * 2018-07-02 2021-04-06 Xiamen Koge Micro Tech Co., Ltd. Movable valve core and electromagnetic valve comprising the same
BR112020026823A2 (pt) * 2018-07-03 2021-04-06 Baxter International Inc. Sistema e método de condicionamento de cassete descartável
CN108799073A (zh) * 2018-07-25 2018-11-13 上海江浪流体机械制造有限公司 一种智能隔膜泵
KR102346844B1 (ko) 2018-07-25 2022-01-03 주식회사 엘지에너지솔루션 고분자 전해질 및 이의 제조방법
US11213616B2 (en) 2018-08-24 2022-01-04 Medtronic, Inc. Recharge solution for zirconium phosphate
CN109080556A (zh) * 2018-08-28 2018-12-25 赣州蓉江新区车来养汽车养护店 一种汽车隔味小便装置
US11806457B2 (en) 2018-11-16 2023-11-07 Mozarc Medical Us Llc Peritoneal dialysis adequacy meaurements
US11806456B2 (en) 2018-12-10 2023-11-07 Mozarc Medical Us Llc Precision peritoneal dialysis therapy based on dialysis adequacy measurements
JP6737373B2 (ja) * 2019-04-05 2020-08-05 ニプロ株式会社 圧力測定部を有する血液回路
US11396417B2 (en) * 2019-07-30 2022-07-26 Voyager Products Inc. System and method for dispensing liquids
USD939079S1 (en) 2019-08-22 2021-12-21 Icu Medical, Inc. Infusion pump
CN114728116A (zh) 2019-11-12 2022-07-08 费森尤斯医疗护理德国有限责任公司 血液治疗系统
CA3160853A1 (en) 2019-11-12 2021-05-20 Fresenius Medical Care Deutschland Gmbh Blood treatment systems
EP4058088A1 (en) 2019-11-12 2022-09-21 Fresenius Medical Care Deutschland GmbH Blood treatment systems
EP4058093A1 (en) 2019-11-12 2022-09-21 Fresenius Medical Care Deutschland GmbH Blood treatment systems
JP2023514620A (ja) 2020-02-20 2023-04-06 デカ・プロダクツ・リミテッド・パートナーシップ 器官維持および輸送のためのシステムならびに方法
CN116538437A (zh) * 2020-04-07 2023-08-04 添可智能科技有限公司 液体供给系统和残留液体清理方法
WO2022175933A1 (en) * 2021-02-18 2022-08-25 Flight Medical Innovations Ltd. Valve cassette for a turbine mechanical ventilator method for holding airway pressure
AU2022326540A1 (en) 2021-08-09 2024-03-21 Deka Products Limited Partnership System and method for ventilating an organ
US11850344B2 (en) 2021-08-11 2023-12-26 Mozarc Medical Us Llc Gas bubble sensor
US11965763B2 (en) 2021-11-12 2024-04-23 Mozarc Medical Us Llc Determining fluid flow across rotary pump
US11944733B2 (en) 2021-11-18 2024-04-02 Mozarc Medical Us Llc Sodium and bicarbonate control
WO2023110682A2 (en) * 2021-12-15 2023-06-22 Norgren LLC Bioprocessing system and associated sensor manifold
US11635134B1 (en) * 2022-01-14 2023-04-25 Zulu Pods, Inc. Packaged oil delivery for short term lubrication

Citations (76)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2816514A (en) * 1954-09-17 1957-12-17 Designers For Industry Inc Vibratory pump
US3539081A (en) * 1968-07-05 1970-11-10 Jet Spray Cooler Inc Valve for beverage dispensers
US3759483A (en) * 1971-05-14 1973-09-18 T Baxter Fluid actuated control valve
US3827561A (en) * 1972-09-20 1974-08-06 Milton Roy Co Deaerator for dialysis system
US3882861A (en) * 1973-09-24 1975-05-13 Vital Assists Auxiliary control for a blood pump
US4096859A (en) * 1977-04-04 1978-06-27 Agarwal Mahesh C Apparatus for peritoneal dialysis
US4155852A (en) * 1976-11-19 1979-05-22 Halbert Fischel Low leakage current medical instrument
US4266814A (en) * 1979-03-23 1981-05-12 Vfp Corporation Plastic tube adapter
US4282099A (en) * 1979-12-10 1981-08-04 Jones John L Integral partitioned hemodialysis unit
US4322054A (en) * 1980-12-29 1982-03-30 Red Valve Company, Inc. Pinch valve
US4398908A (en) * 1980-11-28 1983-08-16 Siposs George G Insulin delivery system
US4439188A (en) * 1980-09-15 1984-03-27 Baxter Travenol Laboratories, Inc. Tube connector
US4490254A (en) * 1980-02-25 1984-12-25 Bentley Laboratories, Inc. Blood filter
US4501405A (en) * 1983-06-21 1985-02-26 Bunnell Life Systems, Inc. Frictionless valve/pump
US4585442A (en) * 1984-07-26 1986-04-29 Ivy Medical, Inc. Miniature intravenous infusion rate controller
US4623450A (en) * 1981-06-16 1986-11-18 Hospal Industrie Artificial kidney
US4695385A (en) * 1985-04-29 1987-09-22 Colorado Medical, Inc. Dialyzer reuse system
US4828543A (en) * 1986-04-03 1989-05-09 Weiss Paul I Extracorporeal circulation apparatus
US4833329A (en) * 1987-11-20 1989-05-23 Mallinckrodt, Inc. System for generating and containerizing radioisotopes
US5033513A (en) * 1980-10-29 1991-07-23 Proprietary Technology, Inc. Swivelable quick connector assembly
US5061241A (en) * 1989-01-19 1991-10-29 Stephens Jr Harry W Rapid infusion device
US5105981A (en) * 1990-11-19 1992-04-21 Thomas Gehman Selectively shakeable freestanding particulate matter reservoir
US5110477A (en) * 1990-02-13 1992-05-05 Howard David B Dialyzer clearance check system
US5300044A (en) * 1991-09-26 1994-04-05 Baxter International Inc. Intravenous tube safety apparatus
USD350850S (en) * 1993-04-20 1994-09-27 Paolo Maniglio Jewelry case
US5351686A (en) * 1990-10-06 1994-10-04 In-Line Diagnostics Corporation Disposable extracorporeal conduit for blood constituent monitoring
US5385540A (en) * 1993-05-26 1995-01-31 Quest Medical, Inc. Cardioplegia delivery system
US5411472A (en) * 1992-07-30 1995-05-02 Galen Medical, Inc. Low trauma blood recovery system
US5441636A (en) * 1993-02-12 1995-08-15 Cobe Laboratories, Inc. Integrated blood treatment fluid module
US5441343A (en) * 1993-09-27 1995-08-15 Topometrix Corporation Thermal sensing scanning probe microscope and method for measurement of thermal parameters of a specimen
US5527507A (en) * 1992-10-01 1996-06-18 American Sterilizer Company Accumulator based liquid metering system and method
US5541344A (en) * 1994-06-30 1996-07-30 G. D. Searle & Co. Intermediates useful in a process for the preparation of azanoradamantane benzamides
US5591344A (en) * 1995-02-13 1997-01-07 Aksys, Ltd. Hot water disinfection of dialysis machines, including the extracorporeal circuit thereof
US5632894A (en) * 1994-06-24 1997-05-27 Gish Biomedical, Inc. Arterial blood filter with upwardly inclining delivery inlet conduit
US5651765A (en) * 1995-04-27 1997-07-29 Avecor Cardiovascular Inc. Blood filter with concentric pleats and method of use
US5692729A (en) * 1996-02-16 1997-12-02 Vision-Sciences, Inc. Pressure equalized flow control apparatus and method for endoscope channels
US5782508A (en) * 1980-10-29 1998-07-21 Proprietary Technologies, Inc. Swivelable quick connector assembly
US5879316A (en) * 1990-12-28 1999-03-09 University Of Pittsburgh Of The Commonwealth System Of Higher Education Portable and modular cardiopulmonary bypass apparatus and associated aortic balloon catheter and associated method
US5931648A (en) * 1995-05-30 1999-08-03 Servicio Regional De Salud, De La Consejeria De Salud De La Comunidad De Madrid Vacuum actuated tubular blood pumping device with active values and application of the same
US6139819A (en) * 1995-06-07 2000-10-31 Imarx Pharmaceutical Corp. Targeted contrast agents for diagnostic and therapeutic use
US6146523A (en) * 1995-02-13 2000-11-14 Aksys, Ltd. User interface and method for control of medical instruments, such as dialysis machines
US6171261B1 (en) * 1999-08-06 2001-01-09 Becton Dickinson And Company Specimen collection device and method of delivering fluid specimens to test tubes
US6176904B1 (en) * 1999-07-02 2001-01-23 Brij M. Gupta Blood filter
US6491656B1 (en) * 1996-11-22 2002-12-10 Therakos, Inc. Integrated cassette for controlling fluid having an integral filter
US6543814B2 (en) * 2000-08-10 2003-04-08 John M. Bartholomew Quick connector
US6595948B2 (en) * 2000-10-04 2003-07-22 Terumo Kabushiki Kaisha Peritoneal dialysis apparatus
US20030220607A1 (en) * 2002-05-24 2003-11-27 Don Busby Peritoneal dialysis apparatus
US20030220599A1 (en) * 2002-05-24 2003-11-27 Lundtveit Loren M. One-piece tip protector and organizer
US6663359B2 (en) * 1999-07-20 2003-12-16 Deka Products Limited Partnership Pump chamber having at least one spacer for inhibiting the pumping of a gas
US6723062B1 (en) * 1999-09-03 2004-04-20 Baxter International Inc. Fluid pressure actuated blood pumping systems and methods with continuous inflow and pulsatile outflow conditions
US20040101026A1 (en) * 2001-05-23 2004-05-27 Metran Co., Ltd. Inspired air temperature measuring device in respiratory circuit
US20050069427A1 (en) * 2002-09-02 2005-03-31 Christiane Roemuss Housing for a fluid flow engine
US20050095141A1 (en) * 2003-10-30 2005-05-05 Deka Products Limited Partnership System and method for pumping fluid using a pump cassette
US20050126988A1 (en) * 2003-02-19 2005-06-16 Thacker Kris O. Water clarification system with weir
US20050274658A1 (en) * 2004-06-09 2005-12-15 Rosenbaum Benjamin P Dialysis system
US20060002823A1 (en) * 2000-09-11 2006-01-05 Feldstein Mark J Fluidics system
US7124996B2 (en) * 2004-07-16 2006-10-24 Cardinal Health 303, Inc. Automatic clamp apparatus for IV infusion sets used in pump devices
US7175606B2 (en) * 2002-05-24 2007-02-13 Baxter International Inc. Disposable medical fluid unit having rigid frame
US7214210B2 (en) * 1997-08-22 2007-05-08 Deka Products Limited Partnership Cassette and method for drug preparation and delivery
US20070166181A1 (en) * 2002-03-14 2007-07-19 Billy Nilson Ambulatory infusion membrane pump
US7303540B2 (en) * 2004-04-26 2007-12-04 Chf Solutions, Inc. User interface for blood treatment device
US7465285B2 (en) * 2003-09-03 2008-12-16 Therakos, Inc. Control system for driving fluids through an extracorporeal blood circuit
US7488448B2 (en) * 2004-03-01 2009-02-10 Indian Wells Medical, Inc. Method and apparatus for removal of gas bubbles from blood
US7500962B2 (en) * 2002-05-24 2009-03-10 Baxter International Inc. Medical fluid machine with air purging pump
US20090107335A1 (en) * 2007-02-27 2009-04-30 Deka Products Limited Partnership Air trap for a medical infusion device
US20090154524A1 (en) * 2006-04-28 2009-06-18 Agostino Girelli Integrated System for Hydro-Thermo-Sanitary Apparatuses
US20090173682A1 (en) * 2007-11-29 2009-07-09 Thomas Patrick Robinson System and Method for Conducting Hemodialysis and Hemofiltration
US7559524B2 (en) * 1999-07-20 2009-07-14 Deka Products Limited Partnership Tube occluder for occluding collapsible tubes
US7561968B2 (en) * 2004-10-13 2009-07-14 The Boeing Company Scale factor calibration and compensation for angular position resolver
US7727176B2 (en) * 2003-02-07 2010-06-01 Gambro Lundia Ab Machine for extracorporeal blood treatment coupled to a support element
US7776301B2 (en) * 2005-03-17 2010-08-17 Nox Ii, Ltd. Reducing mercury emissions from the burning of coal
US7815595B2 (en) * 2002-05-24 2010-10-19 Baxter International Inc. Automated dialysis pumping system
US7867214B2 (en) * 2002-07-19 2011-01-11 Baxter International Inc. Systems and methods for performing peritoneal dialysis
US7896022B2 (en) * 2006-06-07 2011-03-01 Eaton Corporation On-board refueling vapor recovery system with vent line check valve
US20110092875A1 (en) * 2008-04-30 2011-04-21 Gambro Lundia Ab Degassing device
US20110218600A1 (en) * 2006-04-14 2011-09-08 Deka Products Limited Partnership Heat exchange systems, devices and methods

Family Cites Families (465)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4826A (en) 1846-10-24 Boiler fob
US356997A (en) 1887-02-01 Simeon gil
US482A (en) 1837-11-25 Improvement in spring-saddles
US1693526A (en) 1927-06-15 1928-11-27 Charles S Owens Hinge
US2203859A (en) 1936-05-28 1940-06-11 Brendlin Adolf High pressure membrane
US2339876A (en) 1941-01-13 1944-01-25 Pesco Products Co Accumulator
US2529028A (en) 1947-07-31 1950-11-07 Landon Standard Pools Chemical feeder
US2741099A (en) 1953-02-11 1956-04-10 Brewer Titchener Corp Apparatus for indicating and controlling the temperature of products within predetermined limits
US3016563A (en) 1959-03-04 1962-01-16 Jong George Edward De Combined hinge and catch
US3083943A (en) 1959-07-06 1963-04-02 Anbrey P Stewart Jr Diaphragm-type valve
US3200648A (en) 1963-02-04 1965-08-17 William H Waggaman Method and apparatus for comparing smoking properties of various cigarettes
US3508656A (en) * 1968-04-10 1970-04-28 Milton Roy Co Portable dialysate supply system
US3656873A (en) 1970-11-06 1972-04-18 Peter Schiff Pulsatile by-pass blood pump
US3847408A (en) 1971-09-13 1974-11-12 J King Single shaft sulky
USRE27849E (en) 1971-11-30 1973-12-25 Dynamic action valveless artifjcial heart utilizing dual fluid oscillator
US3936729A (en) * 1974-02-28 1976-02-03 Petrolite Corporation Conductivity measurement probe
FR2326235A1 (fr) 1975-10-01 1977-04-29 Renault Buse elastique a debit variable
AT344309B (de) 1975-11-27 1978-07-10 Felix Dr Med Unger Kuenstliche herzkammer
CA1119971A (en) 1976-09-07 1982-03-16 James T. Hutchisson Hemodialysis system with modular dialysate manifold assembly
US4133312A (en) 1976-10-13 1979-01-09 Cordis Dow Corp. Connector for attachment of blood tubing to external arteriovenous shunts and fistulas
US4161264A (en) 1977-06-17 1979-07-17 Johnson Bryan E Fluid metering and mixing device having inlet and outlet valves
FR2405610A1 (fr) * 1977-10-07 1979-05-04 Leboeuf Lola Dispositif a plaques chauffantes electriques pour appareil de transfusion du sang
US4222127A (en) 1978-06-02 1980-09-16 Donachy And Pierce Blood pump and method of pumping blood
DE2838414C2 (de) 1978-09-02 1984-10-31 Fresenius AG, 6380 Bad Homburg Vorrichtung zur Hämodialyse und zum Entziehen von Ultrafiltrat
DE2843756B2 (de) 1978-10-06 1981-07-09 Hense GmbH & Co, 4930 Detmold Vorrichtung zum Erzeugen eines Aerosols
US4362156A (en) 1979-04-18 1982-12-07 Riverain Corporation Intravenous infusion assembly
US4305702A (en) 1979-09-17 1981-12-15 Hartley E Dale Pump with expandable chamber
FR2487679B1 (fr) 1980-08-01 1985-07-12 Hospal Sodip Rein artificiel - regulation de la pression du liquide de dialyse
US4386634A (en) 1980-10-10 1983-06-07 Renal Systems, Inc. Proportioning system
US4369781A (en) 1981-02-11 1983-01-25 Sherwood Medical Industries Inc. Luer connector
US4731072A (en) 1981-05-11 1988-03-15 Mcneilab, Inc. Apparatus for heating or cooling fluids
US4574876A (en) 1981-05-11 1986-03-11 Extracorporeal Medical Specialties, Inc. Container with tapered walls for heating or cooling fluids
JPS5855863A (ja) 1981-09-30 1983-04-02 Futaba Denjiki Kk 過電流表示器
US4411783A (en) 1981-12-23 1983-10-25 Shiley Incorporated Arterial blood filter with improved gas venting
US4441357A (en) 1982-03-04 1984-04-10 Meadox Instruments, Inc. Pressure monitoring and leak detection method and apparatus
US4479760A (en) 1982-12-28 1984-10-30 Baxter Travenol Laboratories, Inc. Actuator apparatus for a prepackaged fluid processing module having pump and valve elements operable in response to applied pressures
US4479761A (en) 1982-12-28 1984-10-30 Baxter Travenol Laboratories, Inc. Actuator apparatus for a prepackaged fluid processing module having pump and valve elements operable in response to externally applied pressures
WO1984002473A1 (en) 1982-12-28 1984-07-05 Baxter Travenol Lab Prepackaged fluid processing module having pump and valve elements operable in response to applied pressures
US4479762A (en) 1982-12-28 1984-10-30 Baxter Travenol Laboratories, Inc. Prepackaged fluid processing module having pump and valve elements operable in response to applied pressures
US4623334A (en) 1983-03-07 1986-11-18 Vanderbilt University Intravenous drug infusion apparatus
JPS6030489A (ja) 1983-07-30 1985-02-16 Iwaki:Kk ダイヤフラム・ポンプのダイヤフラム
DE3328744A1 (de) 1983-08-09 1985-02-28 Fresenius AG, 6380 Bad Homburg Haemodialysevorrichtung
JPS6077782U (ja) 1983-11-01 1985-05-30 山田油機製造株式会社 ダイアフラム
JPS60102003U (ja) * 1983-12-17 1985-07-11 テルモ株式会社 体外血液循環回路用器具
US4583920A (en) 1983-12-28 1986-04-22 M&T Chemicals Inc. Positive displacement diaphragm pumps employing displacer valves
SE8401778L (sv) 1984-03-30 1985-10-01 Astra Tech Ab Pump, serskilt for blod och liknande
US4664891A (en) 1984-07-23 1987-05-12 Renal Systems, Inc. Dialysis solution preparation from prepackaged dry chemicals
US4680445A (en) 1984-09-06 1987-07-14 Genshiro Ogawa Electronically-controlled heating device for infusion liquids
US4718022A (en) 1985-02-21 1988-01-05 Cochran Michael J Dialysis machine which anticipates concentration changes
JPS61167492U (es) 1985-04-05 1986-10-17
US4666598A (en) 1985-06-25 1987-05-19 Cobe Laboratories, Inc. Apparatus for use with fluid flow transfer device
US4826482A (en) 1986-03-04 1989-05-02 Kamen Dean L Enhanced pressure measurement flow control system
US5178182A (en) 1986-03-04 1993-01-12 Deka Products Limited Partnership Valve system with removable fluid interface
US5575310A (en) 1986-03-04 1996-11-19 Deka Products Limited Partnership Flow control system with volume-measuring system using a resonatable mass
US5401342A (en) 1986-03-04 1995-03-28 Deka Products Limited Partnership Process and energy director for ultrasonic welding and joint produced thereby
US4976162A (en) 1987-09-03 1990-12-11 Kamen Dean L Enhanced pressure measurement flow control system
US5088515A (en) 1989-05-01 1992-02-18 Kamen Dean L Valve system with removable fluid interface
US4778451A (en) 1986-03-04 1988-10-18 Kamen Dean L Flow control system using boyle's law
US5160325A (en) 1986-10-06 1992-11-03 C. R. Bard, Inc. Catheter with novel lumens shapes
US4897184A (en) 1986-10-31 1990-01-30 Cobe Laboratories, Inc. Fluid flow apparatus control and monitoring
JPH04845Y2 (es) 1986-12-29 1992-01-13
US4784495A (en) 1987-02-06 1988-11-15 Gambro Ab System for preparing a fluid intended for a medical procedure by mixing at least one concentrate in powder form with water
EP0288145A1 (en) 1987-03-17 1988-10-26 Kenneth Arthur Logan Disposable pump element for dialysis pump
US4927411A (en) 1987-05-01 1990-05-22 Abbott Laboratories Drive mechanism for disposable fluid infusion pumping cassette
NL8701233A (nl) 1987-05-22 1988-12-16 Medistad Holland Bloedverwarmingstoestel.
JP2513243B2 (ja) 1987-07-24 1996-07-03 東洋紡績株式会社 血液ポンプ
US4822343A (en) 1987-09-21 1989-04-18 Louise Beiser Blood collection device with ejectable tips
DE3734072A1 (de) * 1987-10-08 1989-04-27 Liba Maschf Kettenwirkmaschine mit mittels versatzschrittmotoren verstellbaren legebarren
US4781535A (en) 1987-11-13 1988-11-01 Pulsafeeder, Inc. Apparatus and method for sensing diaphragm failures in reciprocating pumps
EP0544653B1 (en) 1988-01-25 1996-06-05 Baxter International Inc. Injection site
SE465404B (sv) 1988-03-03 1991-09-09 Gambro Ab Dialyssystem
US4863461A (en) 1988-03-21 1989-09-05 Symbion, Inc. Artificial ventricle
DE3882519T2 (de) 1988-04-13 1993-11-11 Med Tech Inc Methode zur Regelung des Wasserentzuges durch Ultrafiltration und Regelungsvorrichtung zur Regelung als Wasserentzugs durch Ultrafiltration während der Hämodialyse.
US4950235A (en) 1988-05-10 1990-08-21 Pacesetter Infusion, Ltd. Container-side occlusion detection system for a medication infusion system
US4976729A (en) 1988-08-15 1990-12-11 University Of Utah Research Foundation Elliptical artificial heart
US5110447A (en) 1988-09-12 1992-05-05 Kasten, Eadie Technology Ltd. Process and apparatus for partial upgrading of a heavy oil feedstock
DE3837498A1 (de) 1988-11-04 1990-05-17 Fresenius Ag Verfahren und vorrichtung zur ultrafiltration bei der haemodialyse
US5074838A (en) 1988-11-07 1991-12-24 Kr Phi Yer Karl K K Extracorporal thermo-therapy device and method for curing diseases using penetrants
JP2975105B2 (ja) 1988-12-29 1999-11-10 アン・ルイス・チヤング ダイヤフラムポンプ
DE3907735A1 (de) 1989-03-10 1990-09-20 Bran & Luebbe Membranpumpe mit freischwingender metallmembran
IE72466B1 (en) 1989-03-17 1997-04-09 Baxter Int Blunt-ended cannula device
US5167837A (en) 1989-03-28 1992-12-01 Fas-Technologies, Inc. Filtering and dispensing system with independently activated pumps in series
US5046496A (en) * 1989-04-26 1991-09-10 Ppg Industries, Inc. Sensor assembly for measuring analytes in fluids
US5000664A (en) 1989-06-07 1991-03-19 Abbott Laboratories Apparatus and method to test for valve leakage in a pump assembly
US5702371A (en) 1989-07-24 1997-12-30 Venetec International, Inc. Tube fitting anchoring system
US5242384A (en) 1989-11-13 1993-09-07 Davol, Inc. Blood pumping and processing system
DE3938662A1 (de) * 1989-11-21 1991-07-18 Fresenius Ag Verfahren zur in-vivo-bestimmung von parametern der haemodialyse
US5062774A (en) 1989-12-01 1991-11-05 Abbott Laboratories Solution pumping system including disposable pump cassette
US5125069A (en) 1989-12-22 1992-06-23 Netherlands Health Sciences Blood warmer
US5278072A (en) 1990-04-26 1994-01-11 Minnesota Mining And Manufacturing Company Calibration system and housing
CN1057786A (zh) 1990-07-06 1992-01-15 张任谦 隔膜泵
GB2248927B (en) * 1990-10-17 1994-04-20 Danby Medical Ltd A device for detecting air in fluid conducting tubing
US5098262A (en) 1990-12-28 1992-03-24 Abbott Laboratories Solution pumping system with compressible pump cassette
US5116316A (en) 1991-02-25 1992-05-26 Baxter International Inc. Automatic in-line reconstitution system
US5381510A (en) 1991-03-15 1995-01-10 In-Touch Products Co. In-line fluid heating apparatus with gradation of heat energy from inlet to outlet
US5245693A (en) 1991-03-15 1993-09-14 In-Touch Products Co. Parenteral fluid warmer apparatus and disposable cassette utilizing thin, flexible heat-exchange membrane
US5247434A (en) 1991-04-19 1993-09-21 Althin Medical, Inc. Method and apparatus for kidney dialysis
US5326476A (en) 1991-04-19 1994-07-05 Althin Medical, Inc. Method and apparatus for kidney dialysis using machine with programmable memory
US5486286A (en) 1991-04-19 1996-01-23 Althin Medical, Inc. Apparatus for performing a self-test of kidney dialysis membrane
US5336165A (en) 1991-08-21 1994-08-09 Twardowski Zbylut J Artificial kidney for frequent (daily) Hemodialysis
US5902476A (en) 1991-08-21 1999-05-11 Twardowski; Zbylut J. Artificial kidney for frequent (daily) hemodialysis
JPH0523123U (ja) * 1991-09-05 1993-03-26 株式会社三陽電機製作所 透析液濃度測定用電極
US5755683A (en) 1995-06-07 1998-05-26 Deka Products Limited Partnership Stopcock valve
US5275724A (en) 1991-12-10 1994-01-04 Millipore Corporation Connector apparatus and system
WO1993012825A1 (en) 1991-12-20 1993-07-08 Abbott Laboratories Automated drug infusion system with autopriming
IT1250558B (it) 1991-12-30 1995-04-20 Hospal Dasco Spa Macchina per dialisi con controllo della sicurezza e relativo metodo di controllo della sicurezza.
US5267956A (en) 1992-02-05 1993-12-07 Alcon Surgical, Inc. Surgical cassette
US5423738A (en) 1992-03-13 1995-06-13 Robinson; Thomas C. Blood pumping and processing system
US5616248A (en) 1992-04-06 1997-04-01 Schal; Wilfried Method for the preparation of hemodialysis fluids containing bicarbonate
US5302093A (en) * 1992-05-01 1994-04-12 Mcgaw, Inc. Disposable cassette with negative head height fluid supply and method
IE930532A1 (en) * 1993-07-19 1995-01-25 Elan Med Tech Liquid material dispenser and valve
US5476368A (en) 1992-08-20 1995-12-19 Ryder International Corporation Sterile fluid pump diaphragm construction
US5476444A (en) 1992-09-04 1995-12-19 Idt, Inc. Specialized perfusion protocol for whole-body hyperthermia
SE505801C2 (sv) 1992-09-25 1997-10-13 Atlas Copco Tools Ab Skåp för inrymmande av elektronisk utrustning anslutbar till maskiner eller kraftverktyg
USD356997S (en) 1992-09-29 1995-04-04 Helmut H. Lehmann GmbH Multi-plug connector
US5469070A (en) 1992-10-16 1995-11-21 Rosemount Analytical Inc. Circuit for measuring source resistance of a sensor
US5274245A (en) 1992-11-06 1993-12-28 Lee Thomas E Optical liquid level detector using dual varying light emitters
CA2149246C (en) 1992-11-12 2001-08-28 Jeffrey B. Grogan Method and apparatus for kidney dialysis
DE4336336A1 (de) 1992-11-23 1994-05-26 Lang Volker Kasetteninfusionssystem
DE4239937C2 (de) 1992-11-27 1995-08-24 Fresenius Ag Verfahren zur Feststellung der Funktionsfähigkeit einer Teileinrichtung eines Hämodialysegerätes und Vorrichtung zur Durchführung dieses Verfahrens
US5306242A (en) 1992-12-15 1994-04-26 Abbott Laboratories Recirculation through plural pump cassettes for a solution compounding apparatus
GB2273533B (en) 1992-12-18 1996-09-25 Minnesota Mining & Mfg Pumping cassette with integral manifold
WO1994016226A1 (en) 1992-12-30 1994-07-21 Abbott Laboratories Diaphragm for solution pumping system
US5362383A (en) 1993-01-13 1994-11-08 Ecowater Systems, Inc. Self-contained reverse osmosis electronic monitoring system
JPH06237988A (ja) 1993-02-19 1994-08-30 Aisin Seiki Co Ltd 人工心臓ポンプ装置
USD350823S (en) 1993-02-24 1994-09-20 Deka Products Limited Partnership Rigid portion of disposable parenteral-fluid cassette
US5324422A (en) 1993-03-03 1994-06-28 Baxter International Inc. User interface for automated peritoneal dialysis systems
US5431626A (en) * 1993-03-03 1995-07-11 Deka Products Limited Partnership Liquid pumping mechanisms for peritoneal dialysis systems employing fluid pressure
WO1994020154A1 (en) 1993-03-03 1994-09-15 Deka Products Limited Partnership Peritoneal dialysis systems and methods employing a liquid distribution and pump cassette with self-contained air isolation and removal
US5350357A (en) 1993-03-03 1994-09-27 Deka Products Limited Partnership Peritoneal dialysis systems employing a liquid distribution and pumping cassette that emulates gravity flow
US5474683A (en) 1993-03-03 1995-12-12 Deka Products Limited Partnership Peritoneal dialysis systems and methods employing pneumatic pressure and temperature-corrected liquid volume measurements
US5438510A (en) 1993-03-03 1995-08-01 Deka Products Limited Partnership User interface and monitoring functions for automated peritoneal dialysis systems
US5413566A (en) 1993-03-16 1995-05-09 Micropump Corporation Line clamp
FR2702962B1 (fr) 1993-03-22 1995-04-28 Hospal Ind Dispositif et procédé de contrôle de la balance des fluides sur un circuit extracorporel de sang.
US5410255A (en) 1993-05-07 1995-04-25 Perma-Pipe, Inc. Method and apparatus for detecting and distinguishing leaks using reflectometry and conductivity tests
US5645531A (en) 1993-05-26 1997-07-08 Quest Medical, Inc. Constant pressure blood mixture delivery system and method
JP2576760B2 (ja) 1993-06-08 1997-01-29 日本電気株式会社 微小電界放出冷陰極とその製造方法
US5349896A (en) 1993-06-14 1994-09-27 W. L. Gore & Associates, Inc. Pump diaphragm
US5398851A (en) 1993-08-06 1995-03-21 River Medical, Inc. Liquid delivery device
US5395316A (en) 1993-08-11 1995-03-07 Med-Pro Design, Inc. Triple lumen catheter
GB9325591D0 (en) 1993-12-14 1994-02-16 Somerset Technical Lab Ltd Leakage detection
JP2912801B2 (ja) * 1993-10-06 1999-06-28 株式会社三陽電機製作所 血液透析装置
US5420962A (en) 1993-10-25 1995-05-30 Bakke; Allan P. Convection blood warming system with disposable flattened tube envelope having vent incorporating a hydrophobic filter
US5431627A (en) 1993-11-12 1995-07-11 Abbott Laboratories Cassette identification system for use with a multi-program drug infusion pump
US5499909A (en) 1993-11-17 1996-03-19 Aisin Seiki Kabushiki Kaisha Of Kariya Pneumatically driven micro-pump
US5482440A (en) 1993-12-22 1996-01-09 Baxter Int Blood processing systems using a peristaltic pump module with valve and sensing station for operating a peristaltic pump tube cassette
US5427509A (en) * 1993-12-22 1995-06-27 Baxter International Inc. Peristaltic pump tube cassette with angle pump tube connectors
US5480294A (en) * 1993-12-22 1996-01-02 Baxter International Inc. Peristaltic pump module having jaws for gripping a peristaltic pump tube cassett
US5462416A (en) * 1993-12-22 1995-10-31 Baxter International Inc. Peristaltic pump tube cassette for blood processing systems
US5680111A (en) 1994-02-05 1997-10-21 Baxter International Inc. Dual sensor air-in-line detector
US5460619A (en) 1994-04-04 1995-10-24 Esrock; Bernard S. Disposable tubular device and method
US5441231A (en) 1994-05-17 1995-08-15 Payne; Barrett M. M. Valve closing actuator
DE4421126A1 (de) * 1994-06-16 1995-12-21 Fresenius Ag Peritonealdialysegerät
FR2723002B1 (fr) 1994-07-26 1996-09-06 Hospal Ind Dispositif et procede pour preparer un liquide de traitement par filtration
US5581687A (en) 1994-11-10 1996-12-03 Baxter International Inc. Interactive control systems for medical processing devices
US5593290A (en) * 1994-12-22 1997-01-14 Eastman Kodak Company Micro dispensing positive displacement pump
US5755275A (en) 1995-01-25 1998-05-26 Delta Temax Inc. Tubed lamination heat transfer articles and method of manufacture
US6153102A (en) 1995-02-13 2000-11-28 Aksys, Ltd. Disinfection of dead-ended lines in medical instruments
US5932103A (en) 1995-02-13 1999-08-03 Aksys, Ltd. Withdrawal of priming fluid from extracorporeal circuit of hemodialysis machines or the like
US5932110A (en) 1995-02-13 1999-08-03 Aksys, Ltd. Dialysate conductivity adjustment in a batch dialysate preparation system
SE9500557D0 (sv) 1995-02-15 1995-02-15 Astra Ab Pump chamber and valve for a pumpchamber
US6044868A (en) 1995-02-24 2000-04-04 Arlington Industries, Inc. Watertight fitting for flexible non-metallic conduit
US5640995A (en) * 1995-03-14 1997-06-24 Baxter International Inc. Electrofluidic standard module and custom circuit board assembly
US5586438A (en) 1995-03-27 1996-12-24 Organ, Inc. Portable device for preserving organs by static storage or perfusion
US5578012A (en) 1995-04-24 1996-11-26 Deka Products Limited Partnership Medical fluid pump
US5839715A (en) 1995-05-16 1998-11-24 Alaris Medical Systems, Inc. Medical adapter having needleless valve and sharpened cannula
US5729653A (en) 1995-06-07 1998-03-17 Urosurge, Inc. Fluid warming system
US5676644A (en) 1995-06-07 1997-10-14 Cobe Laboratories, Inc. Extracorporeal blood processing methods and apparatus
US6709417B1 (en) 1995-06-07 2004-03-23 Deka Products Limited Partnership Valve for intravenous-line flow-control system
US5609770A (en) 1995-06-07 1997-03-11 Cobe Laboratories, Inc. Graphical operator machine interface and method for information entry and selection in a dialysis machine
US5650071A (en) 1995-06-07 1997-07-22 Cobe Laboratories, Inc. Technique for priming and recirculating fluid through a dialysis machine to prepare the machine for use
US6165154A (en) 1995-06-07 2000-12-26 Deka Products Limited Partnership Cassette for intravenous-line flow-control system
US5772624A (en) 1995-07-20 1998-06-30 Medisystems Technology Corporation Reusable blood lines
US5776098A (en) 1995-08-03 1998-07-07 Medela, Incorporated Diaphragm pump and pump mounted in a carrying case useful in breast pumping
US5730720A (en) 1995-08-18 1998-03-24 Ip Scientific, Inc. Perfusion hyperthermia treatment system and method
US5674190A (en) 1995-08-28 1997-10-07 Organetics, Ltd. Extracorporeal whole body hyperthermia using alpha-stat regulation of blood pH and pCO2
US5938634A (en) 1995-09-08 1999-08-17 Baxter International Inc. Peritoneal dialysis system with variable pressure drive
US5674109A (en) 1995-09-13 1997-10-07 Ebara Corporation Apparatus and method for polishing workpiece
US6331778B1 (en) 1995-09-27 2001-12-18 Leak Location Services, Inc. Methods for detecting and locating leaks in containment facilities using electrical potential data and electrical resistance tomographic imaging techniques
JPH0999060A (ja) 1995-10-04 1997-04-15 Terumo Corp 拍動型血液ポンプ
US5638737A (en) 1995-11-27 1997-06-17 Quest Medical, Inc. Spline pumping assembly
CA2186805C (en) * 1995-12-01 2001-03-27 Christopher C. Jung Apparatus and method for sensing fluid level
DE19546028C2 (de) 1995-12-09 2000-04-27 Fresenius Ag Bilanzierdisposable zum Bilanzieren von Flüssigkeiten für eine medizinische Behandlungsvorrichtung sowie eine medizinische Behandlungsvorrichtung mit einem Systemeinschub zur Aufnahme eines derartigen Bilanzierdisposables
GB9607471D0 (en) * 1996-04-10 1996-06-12 Baxter Int Volumetric infusion pump
JPH09287441A (ja) * 1996-04-25 1997-11-04 Tenetsukusu:Kk エンジンの排気処理用二次空気の制御弁
US6146354A (en) 1996-05-24 2000-11-14 Horizon Medical Products Asymmetrical multi-lumen apheresis catheter with balanced flow rates
JPH09327511A (ja) * 1996-06-12 1997-12-22 A S A Sangyo Kk 腹膜透析液の回収・再生方法並びにそのための処理装置及び付属器具
JP3865150B2 (ja) 1996-09-18 2007-01-10 株式会社ジェイ・エム・エス 血液浄化装置
US6783328B2 (en) 1996-09-30 2004-08-31 Terumo Cardiovascular Systems Corporation Method and apparatus for controlling fluid pumps
US6047108A (en) 1996-10-01 2000-04-04 Baxter International Inc. Blood warming apparatus
US5875282A (en) 1996-10-21 1999-02-23 Gaymar Industries, Inc. Medical apparatus for warming patient fluids
US5952168A (en) 1996-11-07 1999-09-14 21St Century Medicine, Inc. Method for vitrification of biological materials using alkoxylated compounds
US5882047A (en) 1996-12-20 1999-03-16 Itt Automotive, Inc. Quick connector fluid coupling
JPH10196814A (ja) * 1997-01-17 1998-07-31 Aisan Ind Co Ltd ダイアフラム式流量制御弁
US6673314B1 (en) 1997-02-14 2004-01-06 Nxstage Medical, Inc. Interactive systems and methods for supporting hemofiltration therapies
US6638478B1 (en) 1997-02-14 2003-10-28 Nxstage Medical, Inc. Synchronized volumetric fluid balancing systems and methods
US6852090B2 (en) 1997-02-14 2005-02-08 Nxstage Medical, Inc. Fluid processing systems and methods using extracorporeal fluid flow panels oriented within a cartridge
US6579253B1 (en) 1997-02-14 2003-06-17 Nxstage Medical, Inc. Fluid processing systems and methods using extracorporeal fluid flow panels oriented within a cartridge
WO2001037786A2 (en) * 1997-02-14 2001-05-31 Nxstage Medical, Inc. Fluid processing systems and methods using extracorporeal fluid flow panels oriented within a cartridge
US6419462B1 (en) * 1997-02-24 2002-07-16 Ebara Corporation Positive displacement type liquid-delivery apparatus
JP2001513675A (ja) * 1997-02-27 2001-09-04 ミネソタ マイニング アンド マニュファクチャリング カンパニー 血液のパラメタを測定するためのカセット
DE19708391C1 (de) 1997-03-01 1998-10-22 Fresenius Medical Care De Gmbh Verfahren und Vorrichtung zur Ultrafiltration bei der Hämodialyse
US5899873A (en) 1997-03-24 1999-05-04 Quest Medical, Inc. Biological fluid delivery system
US6768085B2 (en) 2001-07-02 2004-07-27 Medical Solutions, Inc. Medical solution warming system and method of heating and maintaining medical solutions at desired temperatures
US6660974B2 (en) 1997-04-07 2003-12-09 Medical Solutions, Inc. Warming system and method for heating various items utilized in surgical procedures
JP3580661B2 (ja) * 1997-04-08 2004-10-27 愛三工業株式会社 圧力制御弁
SE512266C2 (sv) 1997-07-09 2000-02-21 Gambro Med Tech Ab Förfarande och anordning för integritetstest av ett slangset avsett för användning i en cykler för peritonealdialys
US6070761A (en) 1997-08-22 2000-06-06 Deka Products Limited Partnership Vial loading method and apparatus for intelligent admixture and delivery of intravenous drugs
US6159192A (en) 1997-12-04 2000-12-12 Fowles; Thomas A. Sliding reconstitution device with seal
US6109881A (en) 1998-01-09 2000-08-29 Snodgrass; Ocie T. Gas driven pump for the dispensing and filtering of process fluid
JPH11210633A (ja) 1998-01-30 1999-08-03 Matsushita Electric Works Ltd 吸引装置
US6142164A (en) 1998-03-09 2000-11-07 Ultra Clean Technology Systems & Service, Inc. Method and apparatus for removing leaking gas in an integrated gas panel system
US6325159B1 (en) 1998-03-27 2001-12-04 Hydril Company Offshore drilling system
DE19814695C2 (de) 1998-04-01 2001-09-13 Fresenius Medical Care De Gmbh Kassette zur Förderung von Flüssigkeiten, insbesondere Dialyseflüssigkeiten, Dialysegerät und Verfahren zum Fördern, Bilanzieren, Dosieren und Beheizen eines medizinischen Fluids
US6343614B1 (en) 1998-07-01 2002-02-05 Deka Products Limited Partnership System for measuring change in fluid flow rate within a line
US6041801A (en) 1998-07-01 2000-03-28 Deka Products Limited Partnership System and method for measuring when fluid has stopped flowing within a line
US6175688B1 (en) 1998-07-10 2001-01-16 Belmont Instrument Corporation Wearable intravenous fluid heater
US6331252B1 (en) 1998-07-31 2001-12-18 Baxter International Inc. Methods for priming a blood compartment of a hemodialyzer
SE513522C2 (sv) 1998-09-10 2000-09-25 Gambro Ab Anordning för övervakande av ett fluidrör
JP2000107283A (ja) 1998-10-07 2000-04-18 Nissho Corp 透析装置および洗浄プライミング方法
JP4638986B2 (ja) 1998-10-16 2011-02-23 テルモ メディカル コーポレイション 血液処理装置
US6223130B1 (en) 1998-11-16 2001-04-24 Deka Products Limited Partnership Apparatus and method for detection of a leak in a membrane of a fluid flow control system
JP3997630B2 (ja) 1998-12-03 2007-10-24 ニプロ株式会社 医療用ポンピングカセットおよび医療用ポンピング装置
CN2374187Y (zh) 1999-01-29 2000-04-19 暨南大学 血液透析机
DE19906317C1 (de) 1999-02-16 2000-10-19 Knf Flodos Ag Sursee Membranpumpe
EP1159019B1 (en) * 1999-03-09 2002-11-06 Augustine Medical, Inc. Iv fluid warming system with detection of presence and alignment of cassette
SE9901165D0 (sv) 1999-03-30 1999-03-30 Gambro Lundia Ab Method, apparatus and components of dialysis systems
EP1165148A1 (en) 1999-03-30 2002-01-02 Gambro Lundia AB Method and apparatus for sterilising a heat sensitive fluid
WO2002043864A2 (en) * 2000-11-03 2002-06-06 Clinical Micro Sensors, Inc. Devices and methods for biochip multiplexing
US6579496B1 (en) 1999-05-25 2003-06-17 Viacirq, Inc. Apparatus for implementing hyperthermia
US6321597B1 (en) 1999-05-28 2001-11-27 Deka Products Limited Partnership System and method for measuring volume of liquid in a chamber
DE19925297C1 (de) 1999-06-02 2000-07-13 Braun Melsungen Ag Kartuschenhalter für eine Dialysemaschine
US6406452B1 (en) 1999-06-16 2002-06-18 First Circle Medical, Inc. Bladder catheter for hyperthermia system
US6336911B1 (en) * 1999-06-16 2002-01-08 First Circle Medical, Inc. Thermal sensor for hyperthermia system
DE19928407C1 (de) 1999-06-22 2000-10-26 Fresenius Medical Care De Gmbh Verfahren zur Bestimmung der Leistungsfähigkeit eines Dialysators einer Dialysevorrichtung und Dialysevorrichtung zur Durchführung des Verfahrens
JP2001009025A (ja) 1999-06-30 2001-01-16 Shibuya Kogyo Co Ltd 個人用透析装置
US6302653B1 (en) 1999-07-20 2001-10-16 Deka Products Limited Partnership Methods and systems for detecting the presence of a gas in a pump and preventing a gas from being pumped from a pump
US6905479B1 (en) 1999-07-20 2005-06-14 Deka Products Limited Partnership Pumping cartridge having an integrated filter and method for filtering a fluid with the cartridge
US6604908B1 (en) 1999-07-20 2003-08-12 Deka Products Limited Partnership Methods and systems for pulsed delivery of fluids from a pump
US6416293B1 (en) 1999-07-20 2002-07-09 Deka Products Limited Partnership Pumping cartridge including a bypass valve and method for directing flow in a pumping cartridge
US6284142B1 (en) 1999-09-03 2001-09-04 Baxter International Inc. Sensing systems and methods for differentiating between different cellular blood species during extracorporeal blood separation or processing
IL142692A (en) * 1999-09-03 2005-08-31 Baxter Int Systems and methods for control of pumps
US6270673B1 (en) 1999-09-03 2001-08-07 Baxter International Inc. Door latching assembly for holding a fluid pressure actuated cassette during use
US6261065B1 (en) 1999-09-03 2001-07-17 Baxter International Inc. System and methods for control of pumps employing electrical field sensing
US6481980B1 (en) 1999-09-03 2002-11-19 Baxter International Inc. Fluid flow cassette with pressure actuated pump and valve stations
US6949079B1 (en) 1999-09-03 2005-09-27 Baxter International Inc. Programmable, fluid pressure actuated blood processing systems and methods
US20060178612A9 (en) 1999-09-03 2006-08-10 Baxter International Inc. Blood processing systems with fluid flow cassette with a pressure actuated pump chamber and in-line air trap
JP3806859B2 (ja) 1999-09-24 2006-08-09 応研精工株式会社 ダイヤフラムポンプ
US6464666B1 (en) 1999-10-08 2002-10-15 Augustine Medical, Inc. Intravenous fluid warming cassette with stiffening member and integral handle
US6295918B1 (en) 1999-10-15 2001-10-02 John M. Simmons Suspended diaphragm
US6406426B1 (en) 1999-11-03 2002-06-18 Criticare Systems Medical monitoring and alert system for use with therapeutic devices
US6423053B1 (en) 2000-01-12 2002-07-23 Han-Pin Lee Releasable tube assembly
US6347633B1 (en) * 2000-01-14 2002-02-19 First Circle Medical, Inc. Treatment of hepatitis C using hyperthermia
US6497676B1 (en) 2000-02-10 2002-12-24 Baxter International Method and apparatus for monitoring and controlling peritoneal dialysis therapy
WO2001060428A1 (fr) 2000-02-16 2001-08-23 Teijin Limited Dispositif pour preparer une solution de dialyse et substance chimique pulverulente servant a preparer cette derniere
CA2724266C (en) 2000-02-29 2012-12-04 Gen-Probe Incorporated Fluid dispense and liquid surface verification system and method
US7168334B1 (en) 2000-05-30 2007-01-30 Gambro Lundia Ab Arrangement for measuring a property of a fluid present in a tube
US6752599B2 (en) * 2000-06-09 2004-06-22 Alink M, Inc. Apparatus for photoresist delivery
US6595944B2 (en) * 2000-06-17 2003-07-22 Fresenius Medical Care Deutschland Gmbh Dialysis machine and method of operating a dialysis machine
US6517510B1 (en) 2000-06-26 2003-02-11 Gaymar Industries, Inc. Automatic patient control device
US6293108B1 (en) 2000-06-30 2001-09-25 Vortex Aircon Regenerative refrigeration system with mixed refrigerants
US6415797B1 (en) 2000-07-07 2002-07-09 First Circle Medical, Inc. Treatment of human herpesviruses using hyperthermia
AU2001265253A1 (en) 2000-07-07 2002-01-21 First Circle Medical, Inc. Treatment of hiv using hyperthermia
US6503062B1 (en) 2000-07-10 2003-01-07 Deka Products Limited Partnership Method for regulating fluid pump pressure
IT1318743B1 (it) 2000-08-08 2003-09-10 Dideco Spa Unita' pompante pulsatile per fluido, particolarmente sangue.
US6788885B2 (en) 2000-09-01 2004-09-07 Michael Mitsunaga System for heating instillation or transfusion liquids
US6336003B1 (en) 2000-09-01 2002-01-01 Automatic Medical Technologies, Inc. Max one I.V. warmer
DE10046651A1 (de) * 2000-09-20 2002-04-04 Fresenius Medical Care De Gmbh Ventil
IT1320264B1 (it) 2000-09-29 2003-11-26 Gambro Dasco Spa Apparecchiatura di dialisi e metodo di verifica della funzionalita' diuna apparecchiatura di dialisi.
US6785934B2 (en) 2000-10-02 2004-09-07 Cornice Technologies Inc Universal vacuum extension kit
JP4643815B2 (ja) * 2000-10-04 2011-03-02 テルモ株式会社 腹膜透析装置
EP2044965B1 (en) 2000-10-12 2012-12-19 Renal Solutions, Inc. Apparatus for body fluid flow control in extracorporeal fluid treatments
US6468241B1 (en) 2000-10-26 2002-10-22 Chf Solutions, Inc. Artificial kidney set with electronic key
DE10053441B4 (de) 2000-10-27 2004-04-15 Fresenius Medical Care Deutschland Gmbh Disposablekassette mit Dichtungsmembran sowie Ventilaktor hierfür
US6689083B1 (en) 2000-11-27 2004-02-10 Chf Solutions, Inc. Controller for ultrafiltration blood circuit which prevents hypotension by monitoring osmotic pressure in blood
JP4405664B2 (ja) * 2000-12-28 2010-01-27 株式会社ミクニ ダイアフラム式燃料ポンプ
US6814718B2 (en) 2001-01-09 2004-11-09 Rex Medical, L.P Dialysis catheter
US6529775B2 (en) 2001-01-16 2003-03-04 Alsius Corporation System and method employing indwelling RF catheter for systemic patient warming by application of dielectric heating
US6539172B2 (en) 2001-01-31 2003-03-25 Kabushiki Kaisha Sanko Fluid heating device and cartridge for the same
DK1399193T3 (da) 2001-02-16 2014-03-31 Piedmont Renal Clinics P A Automatiseret peritoneal-dialysesystem og fremgangsmåde med in-line-sterilisation af dialysatet
US6531708B1 (en) * 2001-04-16 2003-03-11 Zevex, Inc. Optical bubble detection system
DE10126134B4 (de) 2001-05-29 2004-02-26 W.E.T. Automotive Systems Ag Flächiger Heizelement
US6527758B2 (en) 2001-06-11 2003-03-04 Kam Ko Vial docking station for sliding reconstitution with diluent container
US7641864B2 (en) 2001-06-15 2010-01-05 Avure Technologies Incorporated Thermal sensor connector for pressure vessel
JP2003000706A (ja) 2001-06-19 2003-01-07 Terumo Corp 腹膜透析用回路
EP1453592B1 (en) * 2001-07-16 2009-12-23 Miox Corporation Dual head pump driven membrane system
US6905314B2 (en) 2001-10-16 2005-06-14 Baxter International Inc. Pump having flexible liner and compounding apparatus having such a pump
US6722865B2 (en) 2001-09-07 2004-04-20 Terumorcardiovascular Systems Corporation Universal tube clamp assembly
US6868309B1 (en) 2001-09-24 2005-03-15 Aksys, Ltd. Dialysis machine with symmetric multi-processing (SMP) control system and method of operation
US7241272B2 (en) 2001-11-13 2007-07-10 Baxter International Inc. Method and composition for removing uremic toxins in dialysis processes
US7645253B2 (en) 2001-11-16 2010-01-12 National Quality Care, Inc. Wearable ultrafiltration device
US6608968B2 (en) 2001-11-23 2003-08-19 Allan P Bakke Convection blood warming system with disposable flattened tube envelope incorporating paperboard “needle” for inserting envelope between heating plates and employing active and passive insulation of outlet flow path to provide normothermic fluid at zero to 600 milliliters per minute
US8226605B2 (en) 2001-12-17 2012-07-24 Medical Solutions, Inc. Method and apparatus for heating solutions within intravenous lines to desired temperatures during infusion
ITMI20012829A1 (it) 2001-12-28 2003-06-28 Gambro Dasco Spa Apparecchiatura e metodo di controllo in un circuito extracorporeo disangue
US7122210B2 (en) 2002-01-11 2006-10-17 Baxter International Inc. Bicarbonate-based solutions for dialysis therapies
US7107837B2 (en) * 2002-01-22 2006-09-19 Baxter International Inc. Capacitance fluid volume measurement
US6692457B2 (en) 2002-03-01 2004-02-17 Insulet Corporation Flow condition sensor assembly for patient infusion device
JP2003265599A (ja) 2002-03-15 2003-09-24 Nextier:Kk 血液浄化システム
DE10212247C1 (de) 2002-03-19 2003-12-18 Fresenius Medical Care De Gmbh Verfahren zur Bestimmung eines Behandlungsparameters an einer Hämofiltrationsvorrichtung und Hämofiltrationsvorrichtung zur Anwendung des Verfahrens
AUPS140902A0 (en) 2002-03-27 2002-05-09 Lazer Safe Pty Ltd Multiple laser safety system
US20040254513A1 (en) * 2002-04-10 2004-12-16 Sherwin Shang Conductive polymer materials and applications thereof including monitoring and providing effective therapy
US7138088B2 (en) 2002-04-10 2006-11-21 Baxter International Inc. Access disconnection system and methods
US7052480B2 (en) 2002-04-10 2006-05-30 Baxter International Inc. Access disconnection systems and methods
AU2003230862A1 (en) * 2002-04-11 2003-10-27 Deka Products Limited Partnership System and method for delivering a target volume of fluid
US20040109769A1 (en) 2002-04-12 2004-06-10 Bayer Aktiengesellschaft Diaphragm pump
DE10216146A1 (de) 2002-04-12 2003-10-30 Bayer Ag Membranpumpe
US20040136843A1 (en) * 2002-04-12 2004-07-15 Bayer Aktiengesellschaft Diaphragm pump
DE10218846C1 (de) 2002-04-27 2003-09-18 Fresenius Medical Care De Gmbh Verfahren zur Unterbrechung oder Fortführung einer extrakorporalen Blutbehandlung mit veränderten Flussraten und Vorrichtung zur extrakorporalen Blutbehandlung
ITMI20021028A1 (it) 2002-05-14 2003-11-14 Dideco Spa Unita' pompante di fluido in particolare sangue
MXPA04011616A (es) 2002-05-24 2005-03-31 Baxter Healtchare S A SISTEMAS DE HARDWARE, METODOS Y APARATOS PARA UNA MAQUINA DE DIáLISIS AUTOMáTICA.
US6929751B2 (en) 2002-05-24 2005-08-16 Baxter International Inc. Vented medical fluid tip protector methods
JP4902117B2 (ja) * 2002-05-24 2012-03-21 バクスター・インターナショナル・インコーポレイテッド 自動化透析システム
DE10224750A1 (de) 2002-06-04 2003-12-24 Fresenius Medical Care De Gmbh Vorrichtung zur Behandlung einer medizinischen Flüssigkeit
US20050209547A1 (en) 2002-06-06 2005-09-22 Burbank Jeffrey H Last-chance quality check and/or air/pathogen filter for infusion systems
US20040009096A1 (en) 2002-06-08 2004-01-15 Wellman Parris S. Substantially inertia free hemodialysis
JP3971659B2 (ja) * 2002-06-14 2007-09-05 日機装株式会社 透析液供給装置
DE10227193B4 (de) 2002-06-18 2007-05-10 Ulman Dichtungstechnik Gmbh Verbundmembran für Membranpumpen
DE10227192B4 (de) 2002-06-18 2009-08-06 Ulman Dichtungstechnik Gmbh Verbundmembran für Membranpumpen
JP4133020B2 (ja) * 2002-06-21 2008-08-13 株式会社サカエ 加温器及びこれに用いられるセンサユニット並びに制御システム
JP4066242B2 (ja) * 2002-07-25 2008-03-26 テルモ株式会社 腹膜透析装置及びその制御方法
US7238164B2 (en) 2002-07-19 2007-07-03 Baxter International Inc. Systems, methods and apparatuses for pumping cassette-based therapies
US7175397B2 (en) 2002-09-27 2007-02-13 Pulsafeeder, Inc. Effervescent gas bleeder apparatus
US20040138607A1 (en) * 2002-10-08 2004-07-15 Burbank Jeffrey H. Cartridge-based medical fluid processing system
AU2003287486A1 (en) 2002-11-01 2004-06-07 Nxstage Medical, Inc. Functional isolation of upgradeable components to reduce risk in medical treatment devices
DE10256923B4 (de) 2002-12-05 2013-10-24 Liebherr-France S.A. Verfahren und Vorrichtung zur Bewegungsdämpfung von Hydraulikzylindern mobiler Arbeitsmaschinen
US7232418B2 (en) 2003-02-07 2007-06-19 Gambro Lundia Ab Support element, an integrated module for extracorporeal blood treatment comprising the support element, an apparatus for extracorporeal blood treatment equipped with the integrated module, and an assembly process for an integrated module for extracorporeal blood treatment
DE10317024A1 (de) 2003-04-11 2004-11-11 Fresenius Medical Care Deutschland Gmbh Blutbehandlungsvorrichtung
US7169303B2 (en) 2003-05-28 2007-01-30 Hemocleanse Technologies, Llc Sorbent reactor for extracorporeal blood treatment systems, peritoneal dialysis systems, and other body fluid treatment systems
JP4286073B2 (ja) 2003-06-18 2009-06-24 ニプロ株式会社 透析器接続用カプラ
JP4041018B2 (ja) * 2003-06-25 2008-01-30 Ｔｄｋ株式会社 温度センサ
JP2005013502A (ja) 2003-06-26 2005-01-20 Aisin Seiki Co Ltd 血液ポンプ駆動装置
JP4278450B2 (ja) * 2003-07-24 2009-06-17 三井金属鉱業株式会社 液種検知装置および液種検知方法
ATE422938T1 (de) 2003-08-15 2009-03-15 Gambro Lundia Ab Verbindungsvorrichtung und verfahren zur verbindung von medizinischen untersystemen
JP4732726B2 (ja) 2003-09-09 2011-07-27 セイコーインスツル株式会社 半導体装置の製造方法
GB2405934A (en) * 2003-09-09 2005-03-16 Qinetiq Ltd Resistance strain/moisture gauge
US6826948B1 (en) 2003-10-09 2004-12-07 Delphi Technologies, Inc. Leak detection apparatus for a liquid circulation cooling system
SE0302698L (sv) 2003-10-13 2005-04-14 Gambro Lundia Ab Anordning för genomförande av en peritonealdialys -behandling
US7029456B2 (en) 2003-10-15 2006-04-18 Baxter International Inc. Medical fluid therapy flow balancing and synchronization system
EP1680155B2 (en) 2003-10-28 2015-11-04 Baxter International Inc. Dialysis machine with improved integrity test
US8029454B2 (en) 2003-11-05 2011-10-04 Baxter International Inc. High convection home hemodialysis/hemofiltration and sorbent system
US7776006B2 (en) 2003-11-05 2010-08-17 Baxter International Inc. Medical fluid pumping system having real time volume determination
US8038639B2 (en) 2004-11-04 2011-10-18 Baxter International Inc. Medical fluid system with flexible sheeting disposable unit
US7744553B2 (en) 2003-12-16 2010-06-29 Baxter International Inc. Medical fluid therapy flow control systems and methods
US8672875B2 (en) 2003-12-31 2014-03-18 Carefusion 303, Inc. Medication safety enhancement for secondary infusion
DE602005006748D1 (de) 2004-01-21 2008-06-26 Imi Vision Ltd Fluiddosierung mit pumpeneinheit mit wegwerfmembran
CA2496646A1 (en) * 2004-02-12 2005-08-12 Flowtec Medical Inc. Fluid monitoring device
JP2005253747A (ja) * 2004-03-12 2005-09-22 Medicalseed:Kk 血液浄化装置及びその交換型血液浄化デバイスユニット
JP2005261558A (ja) 2004-03-17 2005-09-29 Toray Medical Co Ltd 血液透析装置の脱血圧測定システム
US20050209563A1 (en) * 2004-03-19 2005-09-22 Peter Hopping Cassette-based dialysis medical fluid therapy systems, apparatuses and methods
US7407443B2 (en) * 2004-09-07 2008-08-05 Nike, Inc. Structure of a golf club head or other ball striking device
US7476209B2 (en) * 2004-12-21 2009-01-13 Therakos, Inc. Method and apparatus for collecting a blood component and performing a photopheresis treatment
JP2006198141A (ja) 2005-01-20 2006-08-03 Toray Medical Co Ltd 血液体外循環装置における異常検知システム
JP2006204343A (ja) 2005-01-25 2006-08-10 Hiroshima Univ 補助人工心臓
GB2423241A (en) 2005-01-25 2006-08-23 Spaceace Ltd Object sensing device associated with moving furniture
JP2006218130A (ja) 2005-02-10 2006-08-24 Terumo Corp 腹膜透析装置、透析液セットおよび腹膜透析装置の制御方法
SE532147C2 (sv) 2005-02-16 2009-11-03 Triomed Ab Bärbart dialyssystem
US7935074B2 (en) 2005-02-28 2011-05-03 Fresenius Medical Care Holdings, Inc. Cassette system for peritoneal dialysis machine
US20060195064A1 (en) 2005-02-28 2006-08-31 Fresenius Medical Care Holdings, Inc. Portable apparatus for peritoneal dialysis therapy
US7563248B2 (en) * 2005-03-17 2009-07-21 Smisson-Cartledge Biomedical Llc Infusion fluid heat exchanger and cartridge
WO2006120415A1 (en) * 2005-05-06 2006-11-16 Imi Vision Limited Dialysis machine
DE102005024363B4 (de) 2005-05-27 2012-09-20 Fresenius Medical Care Deutschland Gmbh Vorrichtung und Verfahren zur Förderung von Flüssigkeiten
US8197231B2 (en) 2005-07-13 2012-06-12 Purity Solutions Llc Diaphragm pump and related methods
US7717682B2 (en) 2005-07-13 2010-05-18 Purity Solutions Llc Double diaphragm pump and related methods
JP2007035582A (ja) 2005-07-29 2007-02-08 Time Engineering Co Ltd 流量制御装置および燃料電池システム
EP1919550B1 (en) 2005-08-05 2013-07-03 Fresenius Medical Care Holdings, Inc. Dual-channel pump for dialysis use
US7857506B2 (en) 2005-12-05 2010-12-28 Sencal Llc Disposable, pre-calibrated, pre-validated sensors for use in bio-processing applications
US20070179436A1 (en) 2005-12-21 2007-08-02 Braig James R Analyte detection system with periodic sample draw and laboratory-grade analyzer
JP2007215557A (ja) 2006-02-14 2007-08-30 Kawasumi Lab Inc 着脱式体外循環回路
US8469331B2 (en) 2006-04-07 2013-06-25 Nxstage Medical, Inc. Filtration system for preparation of fluids for medical applications
CN100460026C (zh) 2006-04-12 2009-02-11 重庆山外山科技有限公司 医用血液透析滤过机
US20140199193A1 (en) 2007-02-27 2014-07-17 Deka Products Limited Partnership Blood treatment systems and methods
US20080240929A1 (en) 2007-03-30 2008-10-02 Deka Products Limited Partnership Pumping Cassette
US8366316B2 (en) 2006-04-14 2013-02-05 Deka Products Limited Partnership Sensor apparatus systems, devices and methods
US10537671B2 (en) 2006-04-14 2020-01-21 Deka Products Limited Partnership Automated control mechanisms in a hemodialysis apparatus
EP2012848B1 (en) 2006-04-27 2019-07-24 Gambro Lundia AB Remote controlled medical apparatus
US20080287854A1 (en) 2006-06-24 2008-11-20 Jiandong Sun Emergency-Disengagement Device for Patients Undergoing Hemodialysis
US20080015515A1 (en) 2006-06-29 2008-01-17 Mark Alan Hopkins Top and bottom clamping for a surgical cassette
EP2046416B1 (en) 2006-07-14 2015-09-16 Gambro Lundia AB Blood processing apparatus
US8926550B2 (en) 2006-08-31 2015-01-06 Fresenius Medical Care Holdings, Inc. Data communication system for peritoneal dialysis machine
US8870811B2 (en) 2006-08-31 2014-10-28 Fresenius Medical Care Holdings, Inc. Peritoneal dialysis systems and related methods
US20080058712A1 (en) 2006-08-31 2008-03-06 Plahey Kulwinder S Peritoneal dialysis machine with dual voltage heater circuit and method of operation
DE102006042336A1 (de) 2006-09-08 2008-03-27 Fresenius Medical Care Deutschland Gmbh Vorrichtung und Verfahren zur Überwachung eines Zugangs zu einem Patienten, insbesondere eines Gefäßzugangs bei einer extrakorporalen Blutbehandlung
FR2907259A1 (fr) 2006-10-13 2008-04-18 St Microelectronics Sa Realisation d'une barriere metallique dans un circuit electronique integre
JP2008104737A (ja) 2006-10-26 2008-05-08 Terumo Corp 腹膜透析装置
CN101206517B (zh) 2006-12-22 2011-06-22 群康科技(深圳)有限公司 电脑
US20080161751A1 (en) 2006-12-29 2008-07-03 Plahey Kulwinder S Peritoneal dialysis therapy validation
US8226293B2 (en) 2007-02-22 2012-07-24 Medical Solutions, Inc. Method and apparatus for measurement and control of temperature for infused liquids
US8042563B2 (en) 2007-02-27 2011-10-25 Deka Products Limited Partnership Cassette system integrated apparatus
US8491184B2 (en) 2007-02-27 2013-07-23 Deka Products Limited Partnership Sensor apparatus systems, devices and methods
US9028691B2 (en) 2007-02-27 2015-05-12 Deka Products Limited Partnership Blood circuit assembly for a hemodialysis system
KR101385448B1 (ko) 2007-02-27 2014-04-15 삼성디스플레이 주식회사 소스 구동 회로 및 이를 구비한 표시 장치
US8357298B2 (en) 2007-02-27 2013-01-22 Deka Products Limited Partnership Hemodialysis systems and methods
US8317492B2 (en) 2007-02-27 2012-11-27 Deka Products Limited Partnership Pumping cassette
CA2681912C (en) 2007-02-27 2015-09-29 Deka Products Limited Partnership Hemodialysis systems and methods
US8425471B2 (en) 2007-02-27 2013-04-23 Deka Products Limited Partnership Reagent supply for a hemodialysis system
US8393690B2 (en) 2007-02-27 2013-03-12 Deka Products Limited Partnership Enclosure for a portable hemodialysis system
WO2008106452A1 (en) 2007-02-27 2008-09-04 Deka Products Limited Partnership Peritoneal dialysis sensor apparatus systems, devices and methods
US8409441B2 (en) 2007-02-27 2013-04-02 Deka Products Limited Partnership Blood treatment systems and methods
US10463774B2 (en) 2007-02-27 2019-11-05 Deka Products Limited Partnership Control systems and methods for blood or fluid handling medical devices
US9517295B2 (en) 2007-02-27 2016-12-13 Deka Products Limited Partnership Blood treatment systems and methods
US8562834B2 (en) 2007-02-27 2013-10-22 Deka Products Limited Partnership Modular assembly for a portable hemodialysis system
WO2008129084A1 (es) 2007-04-23 2008-10-30 Fundación Para La Investigación Biomédica Del Hospital Gregorio Marañon Método y aparato de hemodiafiltración
JP4513824B2 (ja) 2007-04-26 2010-07-28 株式会社ジェイ・エム・エス 腹膜透析装置用液体自動給排装置および該装置を使用した自動腹膜透析装置
US7835074B2 (en) * 2007-06-05 2010-11-16 Sterling Lc Mini-scope for multi-directional imaging
EP2002855B1 (en) 2007-06-14 2012-07-11 RenApta B.V. Artificial kidney
US7957927B2 (en) 2007-07-05 2011-06-07 Baxter International Inc. Temperature compensation for pneumatic pumping system
US8287724B2 (en) 2007-07-05 2012-10-16 Baxter International Inc. Dialysis fluid measurement systems using conductive contacts
US20090007642A1 (en) 2007-07-05 2009-01-08 Baxter International Inc. Dialysis fluid measurement method and apparatus using conductive contacts
US7955295B2 (en) 2007-07-05 2011-06-07 Baxter International Inc. Fluid delivery system with autoconnect features
US7909795B2 (en) 2007-07-05 2011-03-22 Baxter International Inc. Dialysis system having disposable cassette and interface therefore
US7736328B2 (en) 2007-07-05 2010-06-15 Baxter International Inc. Dialysis system having supply container autoconnection
US8496609B2 (en) 2007-07-05 2013-07-30 Baxter International Inc. Fluid delivery system with spiked cassette
US8057423B2 (en) 2007-07-05 2011-11-15 Baxter International Inc. Dialysis system having disposable cassette
US8330579B2 (en) 2007-07-05 2012-12-11 Baxter International Inc. Radio-frequency auto-identification system for dialysis systems
US8512553B2 (en) 2007-07-05 2013-08-20 Baxter International Inc. Extracorporeal dialysis ready peritoneal dialysis machine
US8715235B2 (en) 2007-07-05 2014-05-06 Baxter International Inc. Dialysis system having disposable cassette and heated cassette interface
US7901376B2 (en) 2007-07-05 2011-03-08 Baxter International Inc. Dialysis cassette having multiple outlet valve
US8764702B2 (en) 2007-07-05 2014-07-01 Baxter International Inc. Dialysis system having dual patient line connection and prime
US7790103B2 (en) 2007-07-05 2010-09-07 Baxter International Inc. Extended use dialysis system
US8105266B2 (en) 2007-07-05 2012-01-31 Baxter International Inc. Mobile dialysis system having supply container detection
US7905855B2 (en) 2007-07-05 2011-03-15 Baxter International Inc. Dialysis system having non-invasive temperature sensing
US20090076434A1 (en) 2007-09-13 2009-03-19 Mischelevich David J Method and System for Achieving Volumetric Accuracy in Hemodialysis Systems
US8597505B2 (en) 2007-09-13 2013-12-03 Fresenius Medical Care Holdings, Inc. Portable dialysis machine
EP3150238B1 (en) * 2007-09-19 2018-03-14 Fresenius Medical Care Holdings, Inc. Dialysis systems and related components
US7892197B2 (en) 2007-09-19 2011-02-22 Fresenius Medical Care Holdings, Inc. Automatic prime of an extracorporeal blood circuit
US8444587B2 (en) 2007-10-01 2013-05-21 Baxter International Inc. Fluid and air handling in blood and dialysis circuits
US7938792B2 (en) 2007-10-01 2011-05-10 Baxter International Inc. Adaptive algorithm for access disconnect detection
US7892331B2 (en) 2007-10-01 2011-02-22 Baxter International Inc. Dialysis systems having air separation chambers with internal structures to enhance air removal
ATE536195T1 (de) 2007-10-04 2011-12-15 Gambro Lundia Ab Infusionsgerät
EP2246080B1 (en) * 2007-10-12 2016-02-10 DEKA Products Limited Partnership An extracorporeal blood flow system
US8863772B2 (en) 2008-08-27 2014-10-21 Deka Products Limited Partnership Occluder for a medical infusion system
CA2702385C (en) 2007-10-12 2017-07-18 Deka Products Limited Partnership Apparatus and methods for hemodialysis
US20100056975A1 (en) 2008-08-27 2010-03-04 Deka Products Limited Partnership Blood line connector for a medical infusion device
US8771508B2 (en) 2008-08-27 2014-07-08 Deka Products Limited Partnership Dialyzer cartridge mounting arrangement for a hemodialysis system
US7887495B2 (en) 2007-10-18 2011-02-15 Boyd Lawrence M Protective and cosmetic covering for external fixators
US8858787B2 (en) 2007-10-22 2014-10-14 Baxter International Inc. Dialysis system having non-invasive fluid velocity sensing
US8114276B2 (en) 2007-10-24 2012-02-14 Baxter International Inc. Personal hemodialysis system
US20090113335A1 (en) 2007-10-30 2009-04-30 Baxter International Inc. Dialysis system user interface
US7905853B2 (en) 2007-10-30 2011-03-15 Baxter International Inc. Dialysis system having integrated pneumatic manifold
US8038640B2 (en) 2007-11-26 2011-10-18 Purity Solutions Llc Diaphragm pump and related systems and methods
JP2009125421A (ja) 2007-11-27 2009-06-11 Jms Co Ltd 血液透析装置
US10195330B2 (en) 2008-01-23 2019-02-05 Deka Products Limited Partnership Medical treatment system and methods using a plurality of fluid lines
US9248225B2 (en) 2008-01-23 2016-02-02 Deka Products Limited Partnership Medical treatment system and methods using a plurality of fluid lines
US8708950B2 (en) 2010-07-07 2014-04-29 Deka Products Limited Partnership Medical treatment system and methods using a plurality of fluid lines
EP2096566B1 (en) 2008-02-29 2018-04-04 Fresenius Medical Care Holdings, Inc. Instructional media system for dialysis machine
US20090294359A1 (en) 2008-06-03 2009-12-03 Baxter International Inc. Priming system and method using pumping and gravity
JP5654466B2 (ja) 2008-08-27 2015-01-14 デカ・プロダクツ・リミテッド・パートナーシップ 透析システムの作動方法
EP2334412B1 (en) 2008-10-07 2019-08-21 Fresenius Medical Care Holdings, Inc. Priming system and method for dialysis systems
US8142649B2 (en) 2009-01-29 2012-03-27 Baxter International Inc. Method for optimizing tidal therapies employing ultrafiltrate trending
US8182673B2 (en) 2009-01-29 2012-05-22 Baxter International Inc. Drain and fill logic for automated peritoneal dialysis
WO2010141326A1 (en) 2009-06-02 2010-12-09 Integenx Inc. Fluidic devices with diaphragm valves
WO2010139918A1 (en) 2009-06-03 2010-12-09 The Technology Partnership Plc Pump with disc-shaped cavity
CA2779296C (en) 2009-10-30 2018-02-13 Deka Products Limited Partnership Apparatus and method for detecting disconnection of an intravascular access device
DE102009060330A1 (de) 2009-12-23 2011-06-30 Fresenius Medical Care Deutschland GmbH, 61352 Dialysemaschine, insbesondere Peritonealdialysemaschine
EP3542840B1 (en) 2011-03-23 2023-04-26 NxStage Medical, Inc. Peritoneal dialysis systems
CA3166031A1 (en) 2011-05-24 2012-11-29 Deka Products Limited Partnership Hemodialysis system
US9999717B2 (en) 2011-05-24 2018-06-19 Deka Products Limited Partnership Systems and methods for detecting vascular access disconnection
US8906240B2 (en) 2011-08-29 2014-12-09 Fresenius Medical Care Holdings, Inc. Early detection of low bicarbonate level
WO2013067359A2 (en) 2011-11-04 2013-05-10 Deka Products Limited Partnership Medical treatment system and methods using a plurality of fluid lines
US9364655B2 (en) 2012-05-24 2016-06-14 Deka Products Limited Partnership Flexible tubing occlusion assembly
WO2014144909A2 (en) 2013-03-15 2014-09-18 Deka Products Limited Partnership Blood treatment systems and methods
EP3524291B1 (en) 2014-05-27 2023-11-29 DEKA Products Limited Partnership System for detecting replacement of blood by dialysate solution
EP3148607B1 (en) 2014-05-27 2019-07-10 DEKA Products Limited Partnership Control systems for blood or fluid handling medical devices
CN108884823B (zh) 2016-07-29 2020-01-24 株式会社村田制作所 阀、气体控制装置以及血压计
BR112020019993A2 (pt) 2018-03-30 2021-01-26 Deka Products Limited Partnership cassetes de bombeamento de líquidos e coletor de distribuição de pressão associado e métodos relacionados

Patent Citations (79)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2816514A (en) * 1954-09-17 1957-12-17 Designers For Industry Inc Vibratory pump
US3539081A (en) * 1968-07-05 1970-11-10 Jet Spray Cooler Inc Valve for beverage dispensers
US3759483A (en) * 1971-05-14 1973-09-18 T Baxter Fluid actuated control valve
US3827561A (en) * 1972-09-20 1974-08-06 Milton Roy Co Deaerator for dialysis system
US3882861A (en) * 1973-09-24 1975-05-13 Vital Assists Auxiliary control for a blood pump
US4155852A (en) * 1976-11-19 1979-05-22 Halbert Fischel Low leakage current medical instrument
US4096859A (en) * 1977-04-04 1978-06-27 Agarwal Mahesh C Apparatus for peritoneal dialysis
US4266814A (en) * 1979-03-23 1981-05-12 Vfp Corporation Plastic tube adapter
US4282099A (en) * 1979-12-10 1981-08-04 Jones John L Integral partitioned hemodialysis unit
US4490254A (en) * 1980-02-25 1984-12-25 Bentley Laboratories, Inc. Blood filter
US4439188A (en) * 1980-09-15 1984-03-27 Baxter Travenol Laboratories, Inc. Tube connector
US5033513A (en) * 1980-10-29 1991-07-23 Proprietary Technology, Inc. Swivelable quick connector assembly
US5782508A (en) * 1980-10-29 1998-07-21 Proprietary Technologies, Inc. Swivelable quick connector assembly
US4398908A (en) * 1980-11-28 1983-08-16 Siposs George G Insulin delivery system
US4322054A (en) * 1980-12-29 1982-03-30 Red Valve Company, Inc. Pinch valve
US4623450A (en) * 1981-06-16 1986-11-18 Hospal Industrie Artificial kidney
US4501405A (en) * 1983-06-21 1985-02-26 Bunnell Life Systems, Inc. Frictionless valve/pump
US4585442A (en) * 1984-07-26 1986-04-29 Ivy Medical, Inc. Miniature intravenous infusion rate controller
US4695385A (en) * 1985-04-29 1987-09-22 Colorado Medical, Inc. Dialyzer reuse system
US4828543A (en) * 1986-04-03 1989-05-09 Weiss Paul I Extracorporeal circulation apparatus
US4833329A (en) * 1987-11-20 1989-05-23 Mallinckrodt, Inc. System for generating and containerizing radioisotopes
US5061241A (en) * 1989-01-19 1991-10-29 Stephens Jr Harry W Rapid infusion device
US5110477A (en) * 1990-02-13 1992-05-05 Howard David B Dialyzer clearance check system
US5351686A (en) * 1990-10-06 1994-10-04 In-Line Diagnostics Corporation Disposable extracorporeal conduit for blood constituent monitoring
US5105981A (en) * 1990-11-19 1992-04-21 Thomas Gehman Selectively shakeable freestanding particulate matter reservoir
US5879316A (en) * 1990-12-28 1999-03-09 University Of Pittsburgh Of The Commonwealth System Of Higher Education Portable and modular cardiopulmonary bypass apparatus and associated aortic balloon catheter and associated method
US5300044A (en) * 1991-09-26 1994-04-05 Baxter International Inc. Intravenous tube safety apparatus
US5411472A (en) * 1992-07-30 1995-05-02 Galen Medical, Inc. Low trauma blood recovery system
US5527507A (en) * 1992-10-01 1996-06-18 American Sterilizer Company Accumulator based liquid metering system and method
US5441636A (en) * 1993-02-12 1995-08-15 Cobe Laboratories, Inc. Integrated blood treatment fluid module
USD350850S (en) * 1993-04-20 1994-09-27 Paolo Maniglio Jewelry case
US5385540A (en) * 1993-05-26 1995-01-31 Quest Medical, Inc. Cardioplegia delivery system
US5441343A (en) * 1993-09-27 1995-08-15 Topometrix Corporation Thermal sensing scanning probe microscope and method for measurement of thermal parameters of a specimen
US5632894A (en) * 1994-06-24 1997-05-27 Gish Biomedical, Inc. Arterial blood filter with upwardly inclining delivery inlet conduit
US5541344A (en) * 1994-06-30 1996-07-30 G. D. Searle & Co. Intermediates useful in a process for the preparation of azanoradamantane benzamides
US6146523A (en) * 1995-02-13 2000-11-14 Aksys, Ltd. User interface and method for control of medical instruments, such as dialysis machines
US5591344A (en) * 1995-02-13 1997-01-07 Aksys, Ltd. Hot water disinfection of dialysis machines, including the extracorporeal circuit thereof
US5651765A (en) * 1995-04-27 1997-07-29 Avecor Cardiovascular Inc. Blood filter with concentric pleats and method of use
US5931648A (en) * 1995-05-30 1999-08-03 Servicio Regional De Salud, De La Consejeria De Salud De La Comunidad De Madrid Vacuum actuated tubular blood pumping device with active values and application of the same
US6139819A (en) * 1995-06-07 2000-10-31 Imarx Pharmaceutical Corp. Targeted contrast agents for diagnostic and therapeutic use
US5692729A (en) * 1996-02-16 1997-12-02 Vision-Sciences, Inc. Pressure equalized flow control apparatus and method for endoscope channels
US6491656B1 (en) * 1996-11-22 2002-12-10 Therakos, Inc. Integrated cassette for controlling fluid having an integral filter
US7214210B2 (en) * 1997-08-22 2007-05-08 Deka Products Limited Partnership Cassette and method for drug preparation and delivery
US6176904B1 (en) * 1999-07-02 2001-01-23 Brij M. Gupta Blood filter
US20100296953A1 (en) * 1999-07-20 2010-11-25 Deka Products Limited Partnership Pump chamber configured to contain a residual fluid volume for inhibiting the pumping of a gas
US20090202367A1 (en) * 1999-07-20 2009-08-13 Deka Products Limited Partnership Tube occluder and method for occluding collapsible tubes
US7559524B2 (en) * 1999-07-20 2009-07-14 Deka Products Limited Partnership Tube occluder for occluding collapsible tubes
US6663359B2 (en) * 1999-07-20 2003-12-16 Deka Products Limited Partnership Pump chamber having at least one spacer for inhibiting the pumping of a gas
US6171261B1 (en) * 1999-08-06 2001-01-09 Becton Dickinson And Company Specimen collection device and method of delivering fluid specimens to test tubes
US6723062B1 (en) * 1999-09-03 2004-04-20 Baxter International Inc. Fluid pressure actuated blood pumping systems and methods with continuous inflow and pulsatile outflow conditions
US6543814B2 (en) * 2000-08-10 2003-04-08 John M. Bartholomew Quick connector
US20060002823A1 (en) * 2000-09-11 2006-01-05 Feldstein Mark J Fluidics system
US6595948B2 (en) * 2000-10-04 2003-07-22 Terumo Kabushiki Kaisha Peritoneal dialysis apparatus
US20040101026A1 (en) * 2001-05-23 2004-05-27 Metran Co., Ltd. Inspired air temperature measuring device in respiratory circuit
US20070166181A1 (en) * 2002-03-14 2007-07-19 Billy Nilson Ambulatory infusion membrane pump
US7500962B2 (en) * 2002-05-24 2009-03-10 Baxter International Inc. Medical fluid machine with air purging pump
US7815595B2 (en) * 2002-05-24 2010-10-19 Baxter International Inc. Automated dialysis pumping system
US7175606B2 (en) * 2002-05-24 2007-02-13 Baxter International Inc. Disposable medical fluid unit having rigid frame
US20030220599A1 (en) * 2002-05-24 2003-11-27 Lundtveit Loren M. One-piece tip protector and organizer
US20030220607A1 (en) * 2002-05-24 2003-11-27 Don Busby Peritoneal dialysis apparatus
US7867214B2 (en) * 2002-07-19 2011-01-11 Baxter International Inc. Systems and methods for performing peritoneal dialysis
US20050069427A1 (en) * 2002-09-02 2005-03-31 Christiane Roemuss Housing for a fluid flow engine
US7727176B2 (en) * 2003-02-07 2010-06-01 Gambro Lundia Ab Machine for extracorporeal blood treatment coupled to a support element
US20050126988A1 (en) * 2003-02-19 2005-06-16 Thacker Kris O. Water clarification system with weir
US7465285B2 (en) * 2003-09-03 2008-12-16 Therakos, Inc. Control system for driving fluids through an extracorporeal blood circuit
US20050095141A1 (en) * 2003-10-30 2005-05-05 Deka Products Limited Partnership System and method for pumping fluid using a pump cassette
US7632080B2 (en) * 2003-10-30 2009-12-15 Deka Products Limited Partnership Bezel assembly for pneumatic control
US7488448B2 (en) * 2004-03-01 2009-02-10 Indian Wells Medical, Inc. Method and apparatus for removal of gas bubbles from blood
US7303540B2 (en) * 2004-04-26 2007-12-04 Chf Solutions, Inc. User interface for blood treatment device
US20050274658A1 (en) * 2004-06-09 2005-12-15 Rosenbaum Benjamin P Dialysis system
US7124996B2 (en) * 2004-07-16 2006-10-24 Cardinal Health 303, Inc. Automatic clamp apparatus for IV infusion sets used in pump devices
US7561968B2 (en) * 2004-10-13 2009-07-14 The Boeing Company Scale factor calibration and compensation for angular position resolver
US7776301B2 (en) * 2005-03-17 2010-08-17 Nox Ii, Ltd. Reducing mercury emissions from the burning of coal
US20110218600A1 (en) * 2006-04-14 2011-09-08 Deka Products Limited Partnership Heat exchange systems, devices and methods
US20090154524A1 (en) * 2006-04-28 2009-06-18 Agostino Girelli Integrated System for Hydro-Thermo-Sanitary Apparatuses
US7896022B2 (en) * 2006-06-07 2011-03-01 Eaton Corporation On-board refueling vapor recovery system with vent line check valve
US20090107335A1 (en) * 2007-02-27 2009-04-30 Deka Products Limited Partnership Air trap for a medical infusion device
US20090173682A1 (en) * 2007-11-29 2009-07-09 Thomas Patrick Robinson System and Method for Conducting Hemodialysis and Hemofiltration
US20110092875A1 (en) * 2008-04-30 2011-04-21 Gambro Lundia Ab Degassing device

Cited By (133)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8366316B2 (en) 2006-04-14 2013-02-05 Deka Products Limited Partnership Sensor apparatus systems, devices and methods
US11828279B2 (en) 2006-04-14 2023-11-28 Deka Products Limited Partnership System for monitoring and controlling fluid flow in a hemodialysis apparatus
US11754064B2 (en) 2006-04-14 2023-09-12 Deka Products Limited Partnership Fluid pumping systems, devices and methods
US11725645B2 (en) 2006-04-14 2023-08-15 Deka Products Limited Partnership Automated control mechanisms and methods for controlling fluid flow in a hemodialysis apparatus
US11419965B2 (en) 2006-04-14 2022-08-23 Deka Products Limited Partnership Pumping cassette
US20100327849A1 (en) * 2006-04-14 2010-12-30 Deka Products Limited Partnership Sensor apparatus systems, devices and methods
US10871157B2 (en) 2006-04-14 2020-12-22 Deka Products Limited Partnership Fluid pumping systems, devices and methods
US10537671B2 (en) 2006-04-14 2020-01-21 Deka Products Limited Partnership Automated control mechanisms in a hemodialysis apparatus
US8292594B2 (en) 2006-04-14 2012-10-23 Deka Products Limited Partnership Fluid pumping systems, devices and methods
US10302075B2 (en) 2006-04-14 2019-05-28 Deka Products Limited Partnership Fluid pumping systems, devices and methods
US8968232B2 (en) 2006-04-14 2015-03-03 Deka Products Limited Partnership Heat exchange systems, devices and methods
US8870549B2 (en) 2006-04-14 2014-10-28 Deka Products Limited Partnership Fluid pumping systems, devices and methods
US11110212B2 (en) 2007-02-27 2021-09-07 Deka Products Limited Partnership Blood circuit assembly for a hemodialysis system
US11568043B2 (en) 2007-02-27 2023-01-31 Deka Products Limited Partnership Control systems and methods for blood or fluid handling medical devices
US8366655B2 (en) 2007-02-27 2013-02-05 Deka Products Limited Partnership Peritoneal dialysis sensor apparatus systems, devices and methods
US8393690B2 (en) 2007-02-27 2013-03-12 Deka Products Limited Partnership Enclosure for a portable hemodialysis system
US8409441B2 (en) 2007-02-27 2013-04-02 Deka Products Limited Partnership Blood treatment systems and methods
US8425471B2 (en) 2007-02-27 2013-04-23 Deka Products Limited Partnership Reagent supply for a hemodialysis system
US8459292B2 (en) 2007-02-27 2013-06-11 Deka Products Limited Partnership Cassette system integrated apparatus
US8491184B2 (en) 2007-02-27 2013-07-23 Deka Products Limited Partnership Sensor apparatus systems, devices and methods
US8499780B2 (en) 2007-02-27 2013-08-06 Deka Products Limited Partnership Cassette system integrated apparatus
US8545698B2 (en) 2007-02-27 2013-10-01 Deka Products Limited Partnership Hemodialysis systems and methods
US8562834B2 (en) 2007-02-27 2013-10-22 Deka Products Limited Partnership Modular assembly for a portable hemodialysis system
US10077766B2 (en) 2007-02-27 2018-09-18 Deka Products Limited Partnership Pumping cassette
US8721884B2 (en) 2007-02-27 2014-05-13 Deka Products Limited Partnership Hemodialysis systems and methods
US8721879B2 (en) 2007-02-27 2014-05-13 Deka Products Limited Partnership Hemodialysis systems and methods
US11885758B2 (en) 2007-02-27 2024-01-30 Deka Products Limited Partnership Sensor apparatus systems, devices and methods
US10500327B2 (en) 2007-02-27 2019-12-10 Deka Products Limited Partnership Blood circuit assembly for a hemodialysis system
US11793915B2 (en) 2007-02-27 2023-10-24 Deka Products Limited Partnership Hemodialysis systems and methods
US11779691B2 (en) 2007-02-27 2023-10-10 Deka Products Limited Partnership Pumping cassette
US10463774B2 (en) 2007-02-27 2019-11-05 Deka Products Limited Partnership Control systems and methods for blood or fluid handling medical devices
US8888470B2 (en) 2007-02-27 2014-11-18 Deka Products Limited Partnership Pumping cassette
US8926294B2 (en) 2007-02-27 2015-01-06 Deka Products Limited Partnership Pumping cassette
US10449280B2 (en) 2007-02-27 2019-10-22 Deka Products Limited Partnership Hemodialysis systems and methods
US10441697B2 (en) 2007-02-27 2019-10-15 Deka Products Limited Partnership Modular assembly for a portable hemodialysis system
US8985133B2 (en) 2007-02-27 2015-03-24 Deka Products Limited Partnership Cassette system integrated apparatus
US8992189B2 (en) 2007-02-27 2015-03-31 Deka Products Limited Partnership Cassette system integrated apparatus
US8992075B2 (en) 2007-02-27 2015-03-31 Deka Products Limited Partnership Sensor apparatus systems, devices and methods
US7967022B2 (en) 2007-02-27 2011-06-28 Deka Products Limited Partnership Cassette system integrated apparatus
US9028691B2 (en) 2007-02-27 2015-05-12 Deka Products Limited Partnership Blood circuit assembly for a hemodialysis system
US11752244B2 (en) 2007-02-27 2023-09-12 Deka Products Limited Partnership Blood circuit assembly for a hemodialysis system
US8042563B2 (en) 2007-02-27 2011-10-25 Deka Products Limited Partnership Cassette system integrated apparatus
US9115708B2 (en) 2007-02-27 2015-08-25 Deka Products Limited Partnership Fluid balancing systems and methods
US11724011B2 (en) 2007-02-27 2023-08-15 Deka Products Limited Partnership Blood treatment systems and methods
US11666690B2 (en) 2007-02-27 2023-06-06 Deka Products Limited Partnership Blood treatment systems and methods
US9302037B2 (en) 2007-02-27 2016-04-05 Deka Products Limited Partnership Hemodialysis systems and methods
US11633526B2 (en) 2007-02-27 2023-04-25 Deka Products Limited Partnership Cassette system integrated apparatus
US8273049B2 (en) 2007-02-27 2012-09-25 Deka Products Limited Partnership Pumping cassette
US11529444B2 (en) 2007-02-27 2022-12-20 Deka Products Limited Partnership Blood treatment systems and methods
US9517295B2 (en) 2007-02-27 2016-12-13 Deka Products Limited Partnership Blood treatment systems and methods
US9535021B2 (en) 2007-02-27 2017-01-03 Deka Products Limited Partnership Sensor apparatus systems, devices and methods
US9539379B2 (en) 2007-02-27 2017-01-10 Deka Products Limited Partnership Enclosure for a portable hemodialysis system
US9555179B2 (en) 2007-02-27 2017-01-31 Deka Products Limited Partnership Hemodialysis systems and methods
US9597442B2 (en) 2007-02-27 2017-03-21 Deka Products Limited Partnership Air trap for a medical infusion device
US9603985B2 (en) 2007-02-27 2017-03-28 Deka Products Limited Partnership Blood treatment systems and methods
US9649418B2 (en) 2007-02-27 2017-05-16 Deka Products Limited Partnership Pumping cassette
US9677554B2 (en) 2007-02-27 2017-06-13 Deka Products Limited Partnership Cassette system integrated apparatus
US9700660B2 (en) 2007-02-27 2017-07-11 Deka Products Limited Partnership Pumping cassette
US8317492B2 (en) 2007-02-27 2012-11-27 Deka Products Limited Partnership Pumping cassette
US11311656B2 (en) 2007-02-27 2022-04-26 Deka Products Limited Partnership Modular assembly for a portable hemodialysis system
US10682450B2 (en) 2007-02-27 2020-06-16 Deka Products Limited Partnership Blood treatment systems and methods
US11154646B2 (en) 2007-02-27 2021-10-26 Deka Products Limited Partnership Hemodialysis systems and methods
US11052181B2 (en) 2007-02-27 2021-07-06 Deka Products Limited Partnership Cassette system integrated apparatus
US10098998B2 (en) 2007-02-27 2018-10-16 Deka Products Limited Partnership Air trap for a medical infusion device
US8246826B2 (en) 2007-02-27 2012-08-21 Deka Products Limited Partnership Hemodialysis systems and methods
US10851769B2 (en) 2007-02-27 2020-12-01 Deka Products Limited Partnership Pumping cassette
US10799628B2 (en) 2007-02-27 2020-10-13 Deka Products Limited Partnership Cassette system integrated apparatus
US8357298B2 (en) 2007-02-27 2013-01-22 Deka Products Limited Partnership Hemodialysis systems and methods
US9951768B2 (en) 2007-02-27 2018-04-24 Deka Products Limited Partnership Cassette system integrated apparatus
US10780210B2 (en) 2007-02-27 2020-09-22 Deka Products Limited Partnership Enclosure for a portable hemodialysis system
US10697913B2 (en) 2007-02-27 2020-06-30 Deka Products Limited Partnership Pump and mixing cassette apparatus systems, devices and methods
US9987407B2 (en) 2007-02-27 2018-06-05 Deka Products Limited Partnership Blood circuit assembly for a hemodialysis system
US9272082B2 (en) 2007-02-27 2016-03-01 Deka Products Limited Partnership Pumping cassette
US9925320B2 (en) 2007-10-24 2018-03-27 Baxter International Inc. Renal therapy machine and system including a priming sequence
US10695479B2 (en) 2007-10-24 2020-06-30 Baxter International Inc. Renal therapy machine and method including a priming sequence
US9855377B2 (en) 2007-10-24 2018-01-02 Baxter International Inc. Dialysis system including heparin injection
US11291752B2 (en) 2007-10-24 2022-04-05 Baxter International Inc. Hemodialysis system including a disposable set and a dialysis instrument
US8114276B2 (en) 2007-10-24 2012-02-14 Baxter International Inc. Personal hemodialysis system
US8323492B2 (en) 2007-10-24 2012-12-04 Baxter International Inc. Hemodialysis system having clamping mechanism for peristaltic pumping
US8932469B2 (en) 2007-10-24 2015-01-13 Baxter International Inc. Personal hemodialysis system including priming sequence and methods of same
US8329030B2 (en) 2007-10-24 2012-12-11 Baxter International Inc. Hemodialysis system with cassette and pinch clamp
US8834719B2 (en) 2007-10-24 2014-09-16 Baxter International Inc. Personal hemodialysis system
US9839775B2 (en) 2008-01-23 2017-12-12 Deka Products Limited Partnership Disposable components for fluid line autoconnect systems and methods
US9248225B2 (en) 2008-01-23 2016-02-02 Deka Products Limited Partnership Medical treatment system and methods using a plurality of fluid lines
US9358332B2 (en) 2008-01-23 2016-06-07 Deka Products Limited Partnership Pump cassette and methods for use in medical treatment system using a plurality of fluid lines
US9839776B2 (en) 2008-01-23 2017-12-12 Deka Products Limited Partnership Fluid flow occluder and methods of use for medical treatment systems
US8197439B2 (en) 2008-01-23 2012-06-12 Deka Products Limited Partnership Fluid volume determination for medical treatment system
US9078971B2 (en) 2008-01-23 2015-07-14 Deka Products Limited Partnership Medical treatment system and methods using a plurality of fluid lines
US9028440B2 (en) 2008-01-23 2015-05-12 Deka Products Limited Partnership Fluid flow occluder and methods of use for medical treatment systems
US9987410B2 (en) 2008-01-23 2018-06-05 Deka Products Limited Partnership Fluid line autoconnect apparatus and methods for medical treatment system
US9022969B2 (en) 2008-01-23 2015-05-05 Deka Products Limited Partnership Fluid line autoconnect apparatus and methods for medical treatment system
US20110071465A1 (en) * 2008-01-23 2011-03-24 Deka Research & Development Fluid volume determination for medical treatment system
US8840581B2 (en) 2008-01-23 2014-09-23 Deka Products Limited Partnership Disposable components for fluid line autoconnect systems and methods
US8863772B2 (en) 2008-08-27 2014-10-21 Deka Products Limited Partnership Occluder for a medical infusion system
US8771508B2 (en) 2008-08-27 2014-07-08 Deka Products Limited Partnership Dialyzer cartridge mounting arrangement for a hemodialysis system
US10201650B2 (en) 2009-10-30 2019-02-12 Deka Products Limited Partnership Apparatus and method for detecting disconnection of an intravascular access device
US11197951B2 (en) 2009-10-30 2021-12-14 Deka Products Limited Partnership Apparatus and method for detecting disconnection of an intravascular access device
US9366781B2 (en) 2010-07-07 2016-06-14 Deka Products Limited Partnership Medical treatment system and methods using a plurality of fluid lines
US8708950B2 (en) 2010-07-07 2014-04-29 Deka Products Limited Partnership Medical treatment system and methods using a plurality of fluid lines
US11135348B2 (en) 2011-03-23 2021-10-05 Nxstage Medical, Inc. Peritoneal dialysis systems, devices, and methods
US10688234B2 (en) 2011-03-23 2020-06-23 Nxstage Medical, Inc. Peritoneal dialysis systems, devices, and methods
US9907897B2 (en) 2011-03-23 2018-03-06 Nxstage Medical, Inc. Peritoneal dialysis systems, devices, and methods
US10688235B2 (en) 2011-03-23 2020-06-23 Nxstage Medical, Inc. Peritoneal dialysis systems, devices, and methods
US10046100B2 (en) 2011-03-23 2018-08-14 Nxstage Medical, Inc. Peritoneal dialysis systems, devices, and methods
US11433169B2 (en) 2011-03-23 2022-09-06 Nxstage Medical, Inc. Dialysis systems, devices, and methods
US11224684B2 (en) 2011-03-23 2022-01-18 Nxstage Medical, Inc. Peritoneal dialysis systems, devices, and methods
US11717601B2 (en) 2011-03-23 2023-08-08 Nxstage Medical, Inc. Dialysis systems, devices, and methods
US10603424B2 (en) 2011-03-23 2020-03-31 Nxstage Medical, Inc. Peritoneal dialysis systems, devices, and methods
US11690941B2 (en) 2011-03-23 2023-07-04 Nxstage Medical, Inc. Peritoneal dialysis systems, devices, and methods
US10610630B2 (en) 2011-03-23 2020-04-07 Nxstage Medical, Inc. Peritoneal dialysis systems, devices, and methods
US10898630B2 (en) 2011-03-23 2021-01-26 Nxstage Medical, Inc. Peritoneal dialysis systems, devices, and methods
US11433170B2 (en) 2011-03-23 2022-09-06 Nxstage Medical, Inc. Dialysis systems, devices, and methods
US9717834B2 (en) 2011-05-24 2017-08-01 Deka Products Limited Partnership Blood treatment systems and methods
US11103625B2 (en) 2011-05-24 2021-08-31 Deka Products Limited Partnership Blood treatment systems and methods
US11890403B2 (en) 2011-05-24 2024-02-06 Deka Products Limited Partnership Hemodialysis system
US10780213B2 (en) 2011-05-24 2020-09-22 Deka Products Limited Partnership Hemodialysis system
US11779689B2 (en) 2011-05-24 2023-10-10 Deka Products Limited Partnership Blood treatment systems and methods
US9999717B2 (en) 2011-05-24 2018-06-19 Deka Products Limited Partnership Systems and methods for detecting vascular access disconnection
US11033671B2 (en) 2011-05-24 2021-06-15 Deka Products Limited Partnership Systems and methods for detecting vascular access disconnection
US9724458B2 (en) 2011-05-24 2017-08-08 Deka Products Limited Partnership Hemodialysis system
US9861732B2 (en) 2011-11-04 2018-01-09 Deka Products Limited Partnership Medical treatment system and methods using a plurality of fluid lines
US9981079B2 (en) 2011-11-04 2018-05-29 Deka Products Limited Partnership Medical treatment system and methods using a plurality of fluid lines
US9861733B2 (en) 2012-03-23 2018-01-09 Nxstage Medical Inc. Peritoneal dialysis systems, devices, and methods
US9700711B2 (en) 2012-05-24 2017-07-11 Deka Products Limited Partnership Flexible tubing occlusion assembly
US11766554B2 (en) 2012-05-24 2023-09-26 Deka Products Limited Partnership Flexible tubing occlusion assembly
US10850089B2 (en) 2012-05-24 2020-12-01 Deka Products Limited Partnership Flexible tubing occlusion assembly
US9364655B2 (en) 2012-05-24 2016-06-14 Deka Products Limited Partnership Flexible tubing occlusion assembly
US11939566B2 (en) 2016-11-07 2024-03-26 Deka Products Limited Partnership System and method for creating tissue
US11207454B2 (en) 2018-02-28 2021-12-28 Nxstage Medical, Inc. Fluid preparation and treatment devices methods and systems
US11364328B2 (en) 2018-02-28 2022-06-21 Nxstage Medical, Inc. Fluid preparation and treatment devices methods and systems
US11872337B2 (en) 2018-02-28 2024-01-16 Nxstage Medical, Inc. Fluid preparation and treatment devices methods and systems
US11371498B2 (en) 2018-03-30 2022-06-28 Deka Products Limited Partnership Liquid pumping cassettes and associated pressure distribution manifold and related methods
US11598329B2 (en) 2018-03-30 2023-03-07 Deka Products Limited Partnership Liquid pumping cassettes and associated pressure distribution manifold and related methods

Also Published As

Publication number Publication date
US20140153356A1 (en) 2014-06-05
CN101801432A (zh) 2010-08-11
US20090004033A1 (en) 2009-01-01
JP5319558B2 (ja) 2013-10-16
CN101678159B (zh) 2014-06-04
JP2010519006A (ja) 2010-06-03
EP3195889B1 (en) 2018-11-07
JP6701399B2 (ja) 2020-05-27
US20110299358A1 (en) 2011-12-08
JP6788142B2 (ja) 2020-11-18
JP2023165719A (ja) 2023-11-17
CA3045352C (en) 2022-10-04
JP2022186751A (ja) 2022-12-15
JP2020034002A (ja) 2020-03-05
CN103623472B (zh) 2017-10-03
KR101780501B1 (ko) 2017-09-21
US10851769B2 (en) 2020-12-01
JP2013063325A (ja) 2013-04-11
KR101780501B9 (ko) 2023-08-16
MX368024B (es) 2019-09-13
EP2131886B1 (en) 2017-04-05
BRPI0808038B1 (pt) 2019-05-28
EP3492120A1 (en) 2019-06-05
EP2131886A1 (en) 2009-12-16
JP6891336B2 (ja) 2021-06-18
CA3056513C (en) 2023-01-10
KR101949907B1 (ko) 2019-02-20
US20150196698A1 (en) 2015-07-16
JP7163269B2 (ja) 2022-10-31
MX2022006458A (es) 2022-06-23
JP2019069154A (ja) 2019-05-09
US9272082B2 (en) 2016-03-01
EP4302818A2 (en) 2024-01-10
AU2017200864B2 (en) 2019-08-22
CA3177986A1 (en) 2008-10-02
JP2015083274A (ja) 2015-04-30
KR101839941B9 (ko) 2023-08-16
KR102208486B9 (ko) 2023-08-16
CA2681914C (en) 2017-01-03
US7967022B2 (en) 2011-06-28
CA2681916C (en) 2020-01-07
US20130074959A1 (en) 2013-03-28
KR101949907B9 (ko) 2023-08-16
US8273049B2 (en) 2012-09-25
WO2008106538A2 (en) 2008-09-04
JP2017023766A (ja) 2017-02-02
JP5291003B2 (ja) 2013-09-18
US20080202591A1 (en) 2008-08-28
EP2735324A1 (en) 2014-05-28
AU2008221370B2 (en) 2014-02-20
US8459292B2 (en) 2013-06-11
US20080253912A1 (en) 2008-10-16
CA3169110A1 (en) 2008-09-04
CA3061102A1 (en) 2008-09-04
EP2131887A2 (en) 2009-12-16
US20160175505A1 (en) 2016-06-23
KR101881916B9 (ko) 2023-08-16
CA3191446A1 (en) 2008-09-04
AU2008231167A1 (en) 2008-10-02
MX336999B (es) 2016-02-08
US9550018B2 (en) 2017-01-24
MX2023002425A (es) 2023-03-22
US20200191132A1 (en) 2020-06-18
JP6093083B2 (ja) 2017-03-08
KR20190018554A (ko) 2019-02-22
US20240066197A1 (en) 2024-02-29
US20190186483A1 (en) 2019-06-20
AU2019268166A1 (en) 2019-12-12
JP5643803B2 (ja) 2014-12-17
AU2014202773B2 (en) 2016-11-10
KR102410172B1 (ko) 2022-06-22
JP6010151B2 (ja) 2016-10-19
US8366655B2 (en) 2013-02-05
US20180038357A1 (en) 2018-02-08
CN104174077A (zh) 2014-12-03
KR20160040304A (ko) 2016-04-12
US10415559B2 (en) 2019-09-17
JP2017227218A (ja) 2017-12-28
US20150125319A1 (en) 2015-05-07
KR20210011072A (ko) 2021-01-29
CN104174077B (zh) 2017-07-18
EP2735324B1 (en) 2017-01-04
US20130177457A1 (en) 2013-07-11
EP2131890B1 (en) 2020-07-08
KR20180027652A (ko) 2018-03-14
WO2008106538A3 (en) 2009-02-12
US9649418B2 (en) 2017-05-16
EP4302818A3 (en) 2024-03-27
JP2015033638A (ja) 2015-02-19
JP2023001146A (ja) 2023-01-04
JP7009347B2 (ja) 2022-01-25
KR20150001853A (ko) 2015-01-06
MX2009009219A (es) 2009-10-20
KR102061802B9 (ko) 2023-08-16
KR102410172B9 (ko) 2023-08-16
JP2020127769A (ja) 2020-08-27
EP2131893A1 (en) 2009-12-16
EP3189863A1 (en) 2017-07-12
KR101608166B1 (ko) 2016-03-31
CA3056513A1 (en) 2008-10-02
BRPI0808040B8 (pt) 2021-06-22
EP3195889A1 (en) 2017-07-26
JP6096400B2 (ja) 2017-03-15
US8317492B2 (en) 2012-11-27
WO2008106538A8 (en) 2008-12-31
BR122019010041B8 (pt) 2021-06-22
KR20180029281A (ko) 2018-03-20
KR102208486B1 (ko) 2021-01-27
KR102061802B1 (ko) 2020-01-03
BRPI0808040A2 (pt) 2014-06-17
AU2008221455A1 (en) 2008-09-04
JP2024003214A (ja) 2024-01-11
CA3045352A1 (en) 2008-09-04
KR101881916B1 (ko) 2018-07-26
KR102013245B1 (ko) 2019-08-23
AU2019268166B2 (en) 2022-01-27
JP6001614B2 (ja) 2016-10-05
CA2937204C (en) 2019-07-23
CA2682073C (en) 2019-10-29
JP2015039639A (ja) 2015-03-02
JP2013176633A (ja) 2013-09-09
US20080208103A1 (en) 2008-08-28
US8888470B2 (en) 2014-11-18
BRPI0808040B1 (pt) 2019-09-17
JP2010519007A (ja) 2010-06-03
JP2021094414A (ja) 2021-06-24
EP2131893B1 (en) 2015-07-22
BRPI0808038A2 (pt) 2014-06-17
KR20170029018A (ko) 2017-03-14
AU2008221455B2 (en) 2014-02-27
US9951768B2 (en) 2018-04-24
MX2009009217A (es) 2009-11-09
KR20210011069A (ko) 2021-01-29
EP3578211A1 (en) 2019-12-11
KR20150058389A (ko) 2015-05-28
KR20100014608A (ko) 2010-02-10
WO2008106440A1 (en) 2008-09-04
US20120207627A1 (en) 2012-08-16
CA2937204A1 (en) 2008-09-04
US9700660B2 (en) 2017-07-11
KR20180086287A (ko) 2018-07-30
KR102390789B1 (ko) 2022-04-26
AU2008221370A1 (en) 2008-09-04
JP2010519463A (ja) 2010-06-03
KR101881910B1 (ko) 2018-07-26
KR101769500B1 (ko) 2017-08-18
MX359478B (es) 2018-09-27
US10077766B2 (en) 2018-09-18
KR20190014593A (ko) 2019-02-12
US20080208111A1 (en) 2008-08-28
JP7389073B2 (ja) 2023-11-29
US20170130705A1 (en) 2017-05-11
JP2017124186A (ja) 2017-07-20
JP2019111367A (ja) 2019-07-11
MX2009009218A (es) 2009-11-09
US8926294B2 (en) 2015-01-06
US11419965B2 (en) 2022-08-23
MX2019010859A (es) 2019-10-30
CA3061102C (en) 2023-09-12
KR20180085073A (ko) 2018-07-25
BR122019010041B1 (pt) 2020-11-17
EP2131890A1 (en) 2009-12-16
EP3782669A1 (en) 2021-02-24
JP6625103B2 (ja) 2019-12-25
CN101801432B (zh) 2013-11-13
AU2008231167B2 (en) 2013-10-31
EP3578211B1 (en) 2023-11-29
KR20190100424A (ko) 2019-08-28
JP2021035527A (ja) 2021-03-04
KR101838459B1 (ko) 2018-03-13
US11779691B2 (en) 2023-10-10
EP3189863B1 (en) 2019-04-10
JP2010519011A (ja) 2010-06-03
US20180372084A1 (en) 2018-12-27
KR101713905B1 (ko) 2017-03-09
JP2022008115A (ja) 2022-01-13
KR20200003253A (ko) 2020-01-08
MX2022006460A (es) 2022-06-23
KR102208243B1 (ko) 2021-01-27
US8985133B2 (en) 2015-03-24
CA2681916A1 (en) 2008-09-04
AU2014202773A1 (en) 2014-06-19
JP2013221524A (ja) 2013-10-28
KR20090127144A (ko) 2009-12-09
CA2682073A1 (en) 2008-10-02
JP6208111B2 (ja) 2017-10-04
JP5695129B2 (ja) 2015-04-01
CA2681914A1 (en) 2008-09-04
KR101608166B9 (ko) 2023-08-16
BRPI0808038B8 (pt) 2021-06-22
JP2016195793A (ja) 2016-11-24
CN101678159A (zh) 2010-03-24
EP2131887B1 (en) 2015-04-08
JP7342226B2 (ja) 2023-09-11
KR101945926B1 (ko) 2019-02-11
KR20170096230A (ko) 2017-08-23
AU2017200864A1 (en) 2017-03-16
JP7155335B2 (ja) 2022-10-18
KR101839941B1 (ko) 2018-05-04
CN103623472A (zh) 2014-03-12
JP5174044B2 (ja) 2013-04-03
US20210146028A1 (en) 2021-05-20
MX2009009216A (es) 2009-11-09
AU2022202714A1 (en) 2022-05-19

Similar Documents

Publication Publication Date Title
US11779691B2 (en) Pumping cassette
US20220355006A1 (en) Pumping cassette
US11633526B2 (en) Cassette system integrated apparatus

Legal Events

Date Code Title Description
AS Assignment

Owner name: DEKA PRODUCTS LIMITED PARTNERSHIP, NEW HAMPSHIRE

Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNORS:DEMERS, JASON A.;WILT, MICHAEL J.;GRANT, KEVIN L.;AND OTHERS;REEL/FRAME:020115/0843;SIGNING DATES FROM 20071106 TO 20071107

STCB Information on status: application discontinuation

Free format text: ABANDONED -- FAILURE TO RESPOND TO AN OFFICE ACTION