TWI412368B - 用於治療病毒感染之化合物及醫藥組合物 - Google Patents

用於治療病毒感染之化合物及醫藥組合物 Download PDF

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Publication number
TWI412368B
TWI412368B TW096150890A TW96150890A TWI412368B TW I412368 B TWI412368 B TW I412368B TW 096150890 A TW096150890 A TW 096150890A TW 96150890 A TW96150890 A TW 96150890A TW I412368 B TWI412368 B TW I412368B
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Taiwan
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group
alkyl
compound
substituted
benzyl
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TW096150890A
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English (en)
Chinese (zh)
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TW200843783A (en
Inventor
Jean-Pierre Sommadossi
Gilles Gosselin
Claire Pierra
Christian Perigaud
Suzanne Peyrottes
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Idenix Pharmaceuticals Inc
Centre Nat Rech Scient
Univ Montpellier Ii
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Publication of TW200843783A publication Critical patent/TW200843783A/zh
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    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
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    • A61K31/708—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid having oxo groups directly attached to the purine ring system, e.g. guanosine, guanylic acid
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    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
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    • C07F9/65586—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system at least one of the hetero rings does not contain nitrogen as ring hetero atom
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    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
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    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
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  • Animal Behavior & Ethology (AREA)
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  • Diabetes (AREA)
  • Biotechnology (AREA)
  • Virology (AREA)
  • Cardiology (AREA)
  • Genetics & Genomics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Ophthalmology & Optometry (AREA)
  • Rheumatology (AREA)
  • Urology & Nephrology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Neurology (AREA)
  • Vascular Medicine (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
TW096150890A 2006-12-28 2007-12-28 用於治療病毒感染之化合物及醫藥組合物 TWI412368B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US87794406P 2006-12-28 2006-12-28
US93629007P 2007-06-18 2007-06-18
US98589107P 2007-11-06 2007-11-06

Publications (2)

Publication Number Publication Date
TW200843783A TW200843783A (en) 2008-11-16
TWI412368B true TWI412368B (zh) 2013-10-21

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TW096150890A TWI412368B (zh) 2006-12-28 2007-12-28 用於治療病毒感染之化合物及醫藥組合物
TW096150931A TW200844108A (en) 2006-12-28 2007-12-28 Compounds and pharmaceutical compositions for the treatment of liver disorders

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US (5) US20080261913A1 (enExample)
EP (2) EP2107909A4 (enExample)
JP (3) JP2010514769A (enExample)
KR (1) KR101508018B1 (enExample)
AU (1) AU2007339226B2 (enExample)
BR (1) BRPI0720637A2 (enExample)
CA (2) CA2673722A1 (enExample)
IL (1) IL200116A0 (enExample)
ME (1) ME00816B (enExample)
MX (1) MX2009006851A (enExample)
MY (1) MY169568A (enExample)
NO (1) NO20092585L (enExample)
NZ (1) NZ577999A (enExample)
RU (1) RU2525392C2 (enExample)
SG (1) SG177923A1 (enExample)
TW (2) TWI412368B (enExample)
UA (1) UA96975C2 (enExample)
WO (2) WO2008082601A2 (enExample)

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AU2001272923A1 (en) 2000-05-26 2001-12-11 Idenix (Cayman) Limited Methods and compositions for treating flaviviruses and pestiviruses
CN1849142A (zh) 2002-11-15 2006-10-18 埃迪尼克斯(开曼)有限公司 2′－支链核苷和黄病毒突变
WO2006137953A1 (en) 2005-04-01 2006-12-28 The Regents Of The Univerisity Of California Phosphono-pent-2-en-1-yl nucleosides and analogs
KR20090024834A (ko) 2006-07-05 2009-03-09 인터뮨, 인크. Ｃ형 간염 바이러스 복제의 신규 억제제
EP2103212B1 (en) 2006-12-11 2014-08-06 Japan Science and Technology Agency Plant growth regulator and use thereof
US20080261913A1 (en) * 2006-12-28 2008-10-23 Idenix Pharmaceuticals, Inc. Compounds and pharmaceutical compositions for the treatment of liver disorders
US7964580B2 (en) 2007-03-30 2011-06-21 Pharmasset, Inc. Nucleoside phosphoramidate prodrugs
BRPI0811447A2 (pt) 2007-05-10 2014-10-29 Intermune Inc Compostos, composição farmacêutica e métodos de inibição da atividade da protease ns3/ns4, de tratamento da fibrose hepática e de intensificação da função hepática num indivíduo tendo infecção de vírus da hepatite c.
GB0709791D0 (en) * 2007-05-22 2007-06-27 Angeletti P Ist Richerche Bio Antiviral agents
CA2718396C (en) 2008-03-14 2016-01-05 Toyota Jidosha Kabushiki Kaisha Gene for increasing the production of plant biomass and/or seeds and method for use thereof
WO2009142842A2 (en) 2008-04-15 2009-11-26 Intermune, Inc. Novel macrocyclic inhibitors of hepatitis c virus replication
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