SK286995B6 - Farmaceutický prostriedok na orálne podávanie v tuhej forme obsahujúci kryštalickú polymorfnú hydrochloridovú soľ N-(3-etinylfenyl)-6,7-bis-(2-metoxyetoxy)-4-chinazolínamínu a jeho použitie - Google Patents
Farmaceutický prostriedok na orálne podávanie v tuhej forme obsahujúci kryštalickú polymorfnú hydrochloridovú soľ N-(3-etinylfenyl)-6,7-bis-(2-metoxyetoxy)-4-chinazolínamínu a jeho použitie Download PDFInfo
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- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A—HUMAN NECESSITIES
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
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- A—HUMAN NECESSITIES
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- A61P35/00—Antineoplastic agents
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P35/04—Antineoplastic agents specific for metastasis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
- C07D239/88—Oxygen atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
- C07D239/94—Nitrogen atoms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Oncology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US16490799P | 1999-11-11 | 1999-11-11 | |
| US19319100P | 2000-03-30 | 2000-03-30 | |
| US20642000P | 2000-05-23 | 2000-05-23 | |
| PCT/US2000/031009 WO2001034574A1 (en) | 1999-11-11 | 2000-11-09 | Stable polymorph of n-(3-ethynylphenylamino)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine hydrochloride, methods of production, and pharmaceutical uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SK5812002A3 SK5812002A3 (en) | 2002-09-10 |
| SK286995B6 true SK286995B6 (sk) | 2009-09-07 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SK581-2002A SK286995B6 (sk) | 1999-11-11 | 2000-11-09 | Farmaceutický prostriedok na orálne podávanie v tuhej forme obsahujúci kryštalickú polymorfnú hydrochloridovú soľ N-(3-etinylfenyl)-6,7-bis-(2-metoxyetoxy)-4-chinazolínamínu a jeho použitie |
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| EP (4) | EP2168581A3 (cs) |
| JP (1) | JP4689916B2 (cs) |
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| CN (1) | CN100351241C (cs) |
| AP (1) | AP1434A (cs) |
| AR (1) | AR035563A1 (cs) |
| AT (1) | ATE420645T1 (cs) |
| AU (3) | AU784243B2 (cs) |
| BG (1) | BG65880B1 (cs) |
| BR (1) | BR0015544A (cs) |
| CA (2) | CA2389333C (cs) |
| CL (1) | CL2010000616A1 (cs) |
| CY (1) | CY1112671T1 (cs) |
| CZ (1) | CZ303897B6 (cs) |
| DE (1) | DE60041415D1 (cs) |
| DK (1) | DK1233948T3 (cs) |
| EA (1) | EA005318B1 (cs) |
| ES (1) | ES2320408T3 (cs) |
| GE (1) | GEP20053503B (cs) |
| HK (1) | HK1049663B (cs) |
| HR (1) | HRP20020388B1 (cs) |
| HU (1) | HU226857B1 (cs) |
| IL (2) | IL149222A0 (cs) |
| IS (1) | IS2612B (cs) |
| MA (1) | MA25570A1 (cs) |
| ME (2) | ME00328B (cs) |
| MY (1) | MY129348A (cs) |
| NO (1) | NO327082B1 (cs) |
| NZ (1) | NZ518406A (cs) |
| PL (1) | PL223486B1 (cs) |
| PT (1) | PT1233948E (cs) |
| RS (1) | RS51198B (cs) |
| SI (1) | SI1233948T1 (cs) |
| SK (1) | SK286995B6 (cs) |
| TW (1) | TWI249528B (cs) |
| UA (1) | UA74803C2 (cs) |
| WO (1) | WO2001034574A1 (cs) |
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