SG11201702175YA - Peptidomimetic macrocycles and formulations thereof - Google Patents

Peptidomimetic macrocycles and formulations thereof

Info

Publication number
SG11201702175YA
SG11201702175YA SG11201702175YA SG11201702175YA SG11201702175YA SG 11201702175Y A SG11201702175Y A SG 11201702175YA SG 11201702175Y A SG11201702175Y A SG 11201702175YA SG 11201702175Y A SG11201702175Y A SG 11201702175YA SG 11201702175Y A SG11201702175Y A SG 11201702175YA
Authority
SG
Singapore
Prior art keywords
formulations
peptidomimetic macrocycles
macrocycles
peptidomimetic
Prior art date
Application number
SG11201702175YA
Other languages
English (en)
Inventor
David Allen Annis
Krzysztof Darlak
Chris Rhodes
Sonoko Kanai
Joerg Hoernschemeyer
Michaela Grass
Original Assignee
Aileron Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aileron Therapeutics Inc filed Critical Aileron Therapeutics Inc
Publication of SG11201702175YA publication Critical patent/SG11201702175YA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10Peptides having 12 to 20 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Dermatology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
SG11201702175YA 2014-09-24 2015-09-24 Peptidomimetic macrocycles and formulations thereof SG11201702175YA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201462054842P 2014-09-24 2014-09-24
PCT/US2015/052018 WO2016049355A1 (en) 2014-09-24 2015-09-24 Peptidomimetic macrocycles and formulations thereof

Publications (1)

Publication Number Publication Date
SG11201702175YA true SG11201702175YA (en) 2017-04-27

Family

ID=55582019

Family Applications (2)

Application Number Title Priority Date Filing Date
SG11201702175YA SG11201702175YA (en) 2014-09-24 2015-09-24 Peptidomimetic macrocycles and formulations thereof
SG10201902598VA SG10201902598VA (en) 2014-09-24 2015-09-24 Peptidomimetic macrocycles and formulations thereof

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG10201902598VA SG10201902598VA (en) 2014-09-24 2015-09-24 Peptidomimetic macrocycles and formulations thereof

Country Status (12)

Country Link
US (3) US10905739B2 (https=)
EP (1) EP3197477A4 (https=)
JP (3) JP2018503595A (https=)
KR (1) KR102570210B1 (https=)
CN (2) CN112972378A (https=)
AU (1) AU2015320545C1 (https=)
BR (1) BR112017005736A2 (https=)
CA (1) CA2961029A1 (https=)
IL (1) IL251122B (https=)
MX (1) MX389354B (https=)
SG (2) SG11201702175YA (https=)
WO (1) WO2016049355A1 (https=)

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CN105061577A (zh) 2006-12-14 2015-11-18 爱勒让治疗公司 双巯基大环化系统
ES2398310T3 (es) 2007-02-23 2013-03-15 Aileron Therapeutics, Inc. Péptidos macrocíclicos unidos a triazol
AU2008232709C1 (en) 2007-03-28 2015-01-15 President And Fellows Of Harvard College Stitched polypeptides
WO2010083347A2 (en) 2009-01-14 2010-07-22 Aileron Therapeutics, Inc. Peptidomimetic macrocycles
US20130072439A1 (en) 2009-09-22 2013-03-21 Huw M. Nash Peptidomimetic macrocycles
KR20170058446A (ko) 2010-08-13 2017-05-26 에일러론 테라퓨틱스 인코포레이티드 펩티도미메틱 거대고리
AR088392A1 (es) 2011-10-18 2014-05-28 Aileron Therapeutics Inc Macrociclos peptidomimeticos
BR112015009470A2 (pt) 2012-11-01 2019-12-17 Aileron Therapeutics Inc aminoácidos dissubstituídos e seus métodos de preparação e uso
SG11201702175YA (en) 2014-09-24 2017-04-27 Aileron Therapeutics Inc Peptidomimetic macrocycles and formulations thereof
WO2016049359A1 (en) 2014-09-24 2016-03-31 Aileron Therapeutics, Inc. Peptidomimetic macrocycles and uses thereof
US10253067B2 (en) * 2015-03-20 2019-04-09 Aileron Therapeutics, Inc. Peptidomimetic macrocycles and uses thereof
US10059741B2 (en) 2015-07-01 2018-08-28 Aileron Therapeutics, Inc. Peptidomimetic macrocycles
WO2017040990A1 (en) * 2015-09-03 2017-03-09 Aileron Therapeutics, Inc. Peptidomimetic macrocycles and uses thereof
WO2017173346A1 (en) * 2016-04-01 2017-10-05 Arizona Board Of Regents On Behalf Of The University Of Arizona Par3 mimetic peptides and uses thereof
WO2017205786A1 (en) * 2016-05-27 2017-11-30 Aileron Therapeutics, Inc. Cell permeable peptidomimetic macrocycles
US20170360881A1 (en) * 2016-06-17 2017-12-21 Aileron Therapeutics, Inc. Peptidomimetic macrocycles and uses thereof
WO2018098534A1 (en) * 2016-12-02 2018-06-07 Garvan Institute Of Medical Research Methods of treating cancer and reagents thereof
WO2020023502A1 (en) 2018-07-23 2020-01-30 Aileron Therapeutics, Inc. Peptidomimetic macrocycles and uses thereof
AU2019363588A1 (en) 2018-10-24 2021-05-13 Allysta Pharmaceuticals, Inc. Adiponectin peptidomimetics formulations
EP3938051A4 (en) * 2019-03-15 2022-12-07 Aileron Therapeutics, Inc. PEPTIDOMIMETIC MACROCYCLES AND USES THEREOF
MX2022010320A (es) * 2020-02-21 2023-01-30 Spitfire Pharma Llc Agonistas, formulaciones y metodos de uso de glp-1r y gcgr.
WO2021185382A1 (en) * 2020-03-20 2021-09-23 Techfields Pharma Co. Ltd. Method for improving the stability of a pharmaceutical composition comprising a high penetration drug, and the pharmaceutical composition obtained therefrom
KR20230037502A (ko) * 2020-05-20 2023-03-16 바이사이클티엑스 리미티드 넥틴-4에 특이적인 바이사이클릭 펩티드 리간드 및 이의 용도
AU2021360898A1 (en) * 2020-10-14 2023-03-23 Dana-Farber Cancer Institute, Inc. Chimeric conjugates for degradation of viral and host proteins and methods of use
CN118103047A (zh) * 2021-08-27 2024-05-28 美国瑞根特有限公司 铁组合物及其制备和使用方法
CN120732847B (zh) * 2025-07-16 2026-02-03 安徽农业大学 维替泊芬在制备防治家蚕核型多角体病毒药物中的应用

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