BRPI0920889A2 - macrociclos peptidomiméticos. - Google Patents

macrociclos peptidomiméticos.

Info

Publication number
BRPI0920889A2
BRPI0920889A2 BRPI0920889A BRPI0920889A BRPI0920889A2 BR PI0920889 A2 BRPI0920889 A2 BR PI0920889A2 BR PI0920889 A BRPI0920889 A BR PI0920889A BR PI0920889 A BRPI0920889 A BR PI0920889A BR PI0920889 A2 BRPI0920889 A2 BR PI0920889A2
Authority
BR
Brazil
Prior art keywords
peptidomimetic macrocycles
macrocycles
peptidomimetic
Prior art date
Application number
BRPI0920889A
Other languages
English (en)
Inventor
M Nasch Huw
Han Jia-Wen
Noehre Justin
Kapeller-Libermann Rosana
K Sawyer Tomi
Original Assignee
Aileron Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aileron Therapeutics Inc filed Critical Aileron Therapeutics Inc
Publication of BRPI0920889A2 publication Critical patent/BRPI0920889A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
BRPI0920889A 2008-09-22 2009-09-22 macrociclos peptidomiméticos. BRPI0920889A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US9916508P 2008-09-22 2008-09-22
PCT/US2009/057930 WO2010034031A1 (en) 2008-09-22 2009-09-22 Peptidomimetic macrocycles

Publications (1)

Publication Number Publication Date
BRPI0920889A2 true BRPI0920889A2 (pt) 2017-10-10

Family

ID=41692050

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0920889A BRPI0920889A2 (pt) 2008-09-22 2009-09-22 macrociclos peptidomiméticos.

Country Status (8)

Country Link
US (1) US20120178700A1 (pt)
EP (1) EP2334697A1 (pt)
JP (1) JP2012510430A (pt)
CN (1) CN102884074A (pt)
AU (1) AU2009294874A1 (pt)
BR (1) BRPI0920889A2 (pt)
CA (1) CA2737920A1 (pt)
WO (1) WO2010034031A1 (pt)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7960506B2 (en) 2006-12-14 2011-06-14 Aileron Therapeutics, Inc. Bis-sulfhydryl macrocyclization systems
ES2648687T3 (es) 2007-02-23 2018-01-05 Aileron Therapeutics, Inc. Péptidos macrocíclicos unidos a triazol
CA2682174C (en) 2007-03-28 2021-04-06 President And Fellows Of Harvard College Stitched polypeptides
CN102482336B (zh) 2008-09-22 2015-05-06 爱勒让治疗公司 拟肽大环化合物
BRPI0920899A2 (pt) 2008-11-24 2016-04-26 Aileron Therapeutics Inc macrociclos peptidomiméticos com propriedades melhoradas
AU2010204648B2 (en) 2009-01-14 2016-09-01 Aileron Therapeutics, Inc. Peptidomimetic macrocycles
CN102712675A (zh) 2009-09-22 2012-10-03 爱勒让治疗公司 拟肽大环化合物
WO2012021876A2 (en) 2010-08-13 2012-02-16 Aileron Therapeutics, Inc. Peptidomimetic macrocycles
US9169295B2 (en) 2010-10-13 2015-10-27 Bristol-Myers Squibb Company Macrocycles and macrocycle stabilized peptides
CN108929375A (zh) 2011-10-18 2018-12-04 爱勒让治疗公司 拟肽大环化合物
US9376469B2 (en) 2011-12-21 2016-06-28 New York University Proteolytically resistant hydrogen bond surrogate helices
WO2013123267A1 (en) 2012-02-15 2013-08-22 Aileron Therapeutics, Inc. Triazole-crosslinked and thioether-crosslinked peptidomimetic macrocycles
ES2817877T3 (es) 2012-02-15 2021-04-08 Aileron Therapeutics Inc Macrociclos peptidomiméticos
JP6526563B2 (ja) 2012-11-01 2019-06-05 エイルロン セラピューティクス，インコーポレイテッド 二置換アミノ酸ならびにその調製および使用の方法
JP6822839B2 (ja) 2013-09-13 2021-01-27 ザ・スクリップス・リサーチ・インスティテュート 修飾された治療剤、及びその組成物
KR102455171B1 (ko) 2013-12-18 2022-10-14 더 스크립스 리서치 인스티튜트 변형된 치료제, 스테이플드 펩티드 지질 접합체, 및 이의 조성물
BR112017005736A2 (pt) * 2014-09-24 2017-12-12 Aileron Therapeutics Inc macrociclos peptidomiméticos e formulações dos mesmos
SG10201902594QA (en) 2014-09-24 2019-04-29 Aileron Therapeutics Inc Peptidomimetic macrocycles and uses thereof
CA2979847A1 (en) 2015-03-20 2016-09-29 Aileron Therapeutics, Inc. Peptidomimetic macrocycles and uses thereof
WO2017004548A1 (en) 2015-07-01 2017-01-05 Aileron Therapeutics, Inc. Peptidomimetic macrocycles
CN108368161A (zh) 2015-09-10 2018-08-03 艾瑞朗医疗公司 作为mcl-1调节剂的拟肽大环化合物
US10639348B2 (en) * 2016-03-15 2020-05-05 Idp Discovery Pharma, S.L. Peptides with anti-cancer activity
EP3658576A1 (en) 2017-07-25 2020-06-03 IDP Discovery Pharma, S.L. Anticancer peptides
AU2018311129B2 (en) * 2017-08-01 2022-09-29 Idp Discovery Pharma, S.L. Anticancer peptides
EP3678679A1 (en) * 2017-09-08 2020-07-15 IDP Discovery Pharma, S.L. New treatments of multiple myeloma

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0633933A1 (en) * 1992-03-23 1995-01-18 Imperial Cancer Research Technology Limited Leucine zippers
US7192713B1 (en) * 1999-05-18 2007-03-20 President And Fellows Of Harvard College Stabilized compounds having secondary structure motifs
WO2005118620A2 (en) * 2004-05-27 2005-12-15 New York University Methods for preparing internally constraied peptides and peptidomimetics
US7960506B2 (en) * 2006-12-14 2011-06-14 Aileron Therapeutics, Inc. Bis-sulfhydryl macrocyclization systems
ES2648687T3 (es) * 2007-02-23 2018-01-05 Aileron Therapeutics, Inc. Péptidos macrocíclicos unidos a triazol
CA2682174C (en) * 2007-03-28 2021-04-06 President And Fellows Of Harvard College Stitched polypeptides

Also Published As

Publication number Publication date
US20120178700A1 (en) 2012-07-12
EP2334697A1 (en) 2011-06-22
WO2010034031A1 (en) 2010-03-25
CA2737920A1 (en) 2010-03-25
AU2009294874A1 (en) 2010-03-25
CN102884074A (zh) 2013-01-16
JP2012510430A (ja) 2012-05-10

Similar Documents

Publication Publication Date Title
BRPI0920889A2 (pt) macrociclos peptidomiméticos.
BRPI0918948A2 (pt) macrociclos peptidomiméticos
BRPI0918833A2 (pt) macrociclos peptidomiméticos
BRPI1006139A2 (pt) macrociclos peptidomiméticos
BRPI0920899A2 (pt) macrociclos peptidomiméticos com propriedades melhoradas
BRPI0907754A2 (pt) Macrociclos peptidomiméticos terapêuticos
BRPI0813235A2 (pt) Combinação anti-helmíntica.
BRPI0920428A2 (pt) inalador.
BRPI0912260A2 (pt) tonalizador.
BRPI0920648A2 (pt) Combinações pesticidas contendo sulfoxaflor
BRPI0922391A2 (pt) pneumático.
BRPI0907925A2 (pt) Ativadores de glicoquinase.
BRPI0923418A2 (pt) pneumático.
BRPI0907108A2 (pt) escova de dentes.
BRPI0917446A2 (pt) derivados de acilaminobenzamida.
BRPI0907448A2 (pt) Instrumentos.
BRPI1011794A2 (pt) compartimento.
BRPI0923387A2 (pt) pneumático.
IT1391534B1 (it) Barriera.
IT1392420B1 (it) Lavastoviglie.
IT1396642B1 (it) Statore.
CL2008000325S1 (es) Automovil.
CL2008000916S1 (es) Automovil.
NL2002599A1 (nl) Hoogwerker.
ITME20080002A1 (it) Filcomplex - potabilizzatore di acque.

Legal Events

Date Code Title Description
B08F Application fees: application dismissed [chapter 8.6 patent gazette]
B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]