ES2133295T3 - Peptidos ciclicos y su uso. - Google Patents

Peptidos ciclicos y su uso.

Info

Publication number
ES2133295T3
ES2133295T3 ES92117182T ES92117182T ES2133295T3 ES 2133295 T3 ES2133295 T3 ES 2133295T3 ES 92117182 T ES92117182 T ES 92117182T ES 92117182 T ES92117182 T ES 92117182T ES 2133295 T3 ES2133295 T3 ES 2133295T3
Authority
ES
Spain
Prior art keywords
amino acid
acid waste
waste
formula
cyclic peptides
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92117182T
Other languages
English (en)
Inventor
Mitsuhiro Wakimasu
Takashi Kikuchi
Akira Kawada
Hideo Shirahuji
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP4216019A external-priority patent/JP2677489B2/ja
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Application granted granted Critical
Publication of ES2133295T3 publication Critical patent/ES2133295T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/57536—Endothelin, vasoactive intestinal contractor [VIC]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Endocrinology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Vascular Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

SE PRESENTAN (1) UN HEXAPEPTIDO CICLICO REPRESENTADO POR LA FORMULA [I] O UNA SAL DEL MISMO: EN DONDE X E Y REPRESENTAN CADA UNA RESIDUOS O-AMINOACIDOS. A REPRESENTA UN RESIDUO D-O-AMINOACIDO ACIDICO, B REPRESENTA UN RESIDUO O-AMINOACIDO NEUTRO, C REPRESENTA UN RESIDUO L-OAMINOACIDO Y D REPRESENTA UN RESIDUO D-O-AMINOACIDO QUE TIENE UN GRUPO DE ANILLO AROMATICO; Y (2) UNA COMPOSICION FARMACEUTICA QUE CONTIENE EL PEPTIDO REPRESENTADO POR LA FORMULA [I] O UNA SAL FARMACEUTICAMENTE ACEPTABLE DEL MISMO COMO INGREDIENTE ACTIVO.
ES92117182T 1991-11-19 1992-10-08 Peptidos ciclicos y su uso. Expired - Lifetime ES2133295T3 (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP30363591 1991-11-19
JP3543692 1992-02-21
JP11179292 1992-04-30
JP4216019A JP2677489B2 (ja) 1991-08-13 1992-08-13 環状ペプチドおよびその用途

Publications (1)

Publication Number Publication Date
ES2133295T3 true ES2133295T3 (es) 1999-09-16

Family

ID=27460094

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92117182T Expired - Lifetime ES2133295T3 (es) 1991-11-19 1992-10-08 Peptidos ciclicos y su uso.

Country Status (3)

Country Link
EP (1) EP0552417B1 (es)
ES (1) ES2133295T3 (es)
GR (1) GR3031296T3 (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2135151A1 (en) * 1993-11-08 1995-05-09 Mitsuhiro Wakimasu Cyclic hexapeptides, their production and use
EP0714909A1 (en) * 1994-12-01 1996-06-05 Takeda Chemical Industries, Ltd. Composition for prophylaxis or treatment of pulmonary circulatory diseases
US6251861B1 (en) * 1996-06-27 2001-06-26 Takeda Chemical Industries, Ltd. Treatment of cerebral infarction using cyclic hexapeptides
ATE393783T1 (de) 1999-03-29 2008-05-15 Procter & Gamble Melanocortinrezeptor-liganden
CA2939778C (en) 2007-01-31 2019-01-29 Dana-Farber Cancer Institute, Inc. Stabilized p53 peptides and uses thereof
CA2682174C (en) 2007-03-28 2021-04-06 President And Fellows Of Harvard College Stitched polypeptides
GB2453589A (en) * 2007-10-12 2009-04-15 King S College London Protease inhibition
KR20130099938A (ko) 2010-08-13 2013-09-06 에일러론 테라퓨틱스 인코포레이티드 펩티도미메틱 거대고리
CN104039342A (zh) 2011-10-18 2014-09-10 爱勒让治疗公司 拟肽大环化合物
NZ627528A (en) 2012-02-15 2016-05-27 Aileron Therapeutics Inc Peptidomimetic macrocycles
HK1205454A1 (en) 2012-02-15 2015-12-18 Aileron Therapeutics, Inc. Triazole-crosslinked and thioether-crosslinked peptidomimetic macrocycles
SG11201503052RA (en) 2012-11-01 2015-05-28 Aileron Therapeutics Inc Disubstituted amino acids and methods of preparation and use thereof
MX2017003797A (es) 2014-09-24 2017-06-15 Aileron Therapeutics Inc Macrociclos peptidomimeticos y usos de los mismos.
MX389354B (es) 2014-09-24 2025-03-20 Aileron Therapeutics Inc Macrociclos peptidomimeticos y formulaciones de los mismos.
WO2016154058A1 (en) 2015-03-20 2016-09-29 Aileron Therapeutics, Inc. Peptidomimetic macrocycles and uses thereof
JP2018528217A (ja) 2015-09-10 2018-09-27 エルロン・セラピューティクス・インコーポレイテッドＡｉｌｅｒｏｎ Ｔｈｅｒａｐｅｕｔｉｃｓ，Ｉｎｃ． Ｍｃｌ−１のモジュレーターとしてのペプチド模倣大環状分子

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2032559C (en) * 1989-12-28 2001-11-06 Kiyofumi Ishikawa Endothelin antagonistic cyclic pentapeptides

Also Published As

Publication number Publication date
GR3031296T3 (en) 1999-12-31
EP0552417B1 (en) 1999-07-07
EP0552417A1 (en) 1993-07-28

Similar Documents

Publication Publication Date Title
ES2103857T3 (es) Peptidos ciclicos y su uso.
ES2133295T3 (es) Peptidos ciclicos y su uso.
ES2163444T3 (es) Composiciones y metodos para la administracion oral de farmacos.
SE8602723L (sv) Tiazoler, deras framstellning och farmaceutiska kompositioner innehallande dem
CO4790174A1 (es) Analogos del peptido lh-rh, sus usos y composiciones farmaceuticas que los contienen
ATE189228T1 (de) Peptide mit zyklischen hauptketten, deren herstellung und diese enthaltende pharmazeutische zusammensetzungen
NO20064159L (no) Nye, biologisk aktive polypeptider, deres fremstilling og farmasoytiske preparater inneholdende polypeptidene
EP0695171A1 (en) GONADOTROPINE CONTAINING FREEZER DRIED DROPS
NO870441L (no) Farmasoeytiske preparatformer for stabilisering av alfa-interferon.
DE69521693D1 (de) Taxanderivate enthaltende arzneizubereitungen
PA8451701A1 (es) Formulacion inyectable transparente de compuesto anestesico
NO870560L (no) Nytt farmasoeytisk preparat.
ES2180699T3 (es) Agentes antifungicos peptidicos ciclicos.
ES2064398T3 (es) Un nuevo antibiotico, mersacidina, un procedimiento para su preparacion y su utilizacion como medicamento.
ES2099828T3 (es) Derivado aminoacido.
ATE90359T1 (de) Peptide.
ES2086528T3 (es) Nuevos compuestos biciclicos sustituidos con amino.
DE68906572D1 (de) Peptide mit inhibitorischer wirkung auf enzymatische systeme, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzungen.
GEP20002271B (en) Bicyclic Tachykinins Antagonists, Pharmaceutical Composition on Its Basis and Their Use
ATE216254T1 (de) Pharmazeutische zusammensetzungen enthaltend cyclosporin und einen träger mit mindestens einer ester-alpha-glycerophosphorsäure
RU95109891A (ru) 19,11-перекрытые мостиками 4-эстрены, способ их получения, содержащая их фармацевтическая композиция и промежуточные соединения для их получения
DE69412612D1 (de) Desoxyazaphospholipid-derivate mit inhibierender aktivität auf phospholipase
NO20000424D0 (no) Streptograminer, deres fremstilling samt preparater inneholdende forbindelsene
ES2087178T3 (es) Disulfato de ws7622a, procedimiento para su preparacion y su uso.
DE69433999D1 (de) Entzündungshemmende peptide

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 552417

Country of ref document: ES