PL3229772T3 - 6-arylo-9-glikozylopuryny i ich zastosowanie - Google Patents

6-arylo-9-glikozylopuryny i ich zastosowanie

Info

Publication number
PL3229772T3
PL3229772T3 PL15816356T PL15816356T PL3229772T3 PL 3229772 T3 PL3229772 T3 PL 3229772T3 PL 15816356 T PL15816356 T PL 15816356T PL 15816356 T PL15816356 T PL 15816356T PL 3229772 T3 PL3229772 T3 PL 3229772T3
Authority
PL
Poland
Prior art keywords
glycosylpurines
aryl
Prior art date
Application number
PL15816356T
Other languages
English (en)
Inventor
Karel Dolezal
Lucie PLIHALOVA
Hana VYLICILOVA
Marek Zatloukal
Ondrej PLIHAL
Jiri Voller
Miroslav Strnad
Johannes Van Staden
Ponnusamy BASKARAN
Aloka KUMARI
Adeyemi Oladapo AREMU
Original Assignee
Univerzita Palackého v Olomouci
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univerzita Palackého v Olomouci filed Critical Univerzita Palackého v Olomouci
Publication of PL3229772T3 publication Critical patent/PL3229772T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60—Sugars; Derivatives thereof
    • A61K8/606—Nucleosides; Nucleotides; Nucleic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/08—Anti-ageing preparations
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C07H19/173—Purine radicals with 2-deoxyribosyl as the saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C07H19/19—Purine radicals with arabinosyl as the saccharide radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/7056—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing five-membered rings with nitrogen as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
PL15816356T 2014-12-09 2015-12-02 6-arylo-9-glikozylopuryny i ich zastosowanie PL3229772T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CZ2014875A CZ308881B6 (cs) 2014-12-09 2014-12-09 6-aryl-9-glykosylpuriny a jejich použití
EP15816356.8A EP3229772B1 (en) 2014-12-09 2015-12-02 6-aryl-9-glycosylpurines and use thereof
PCT/CZ2015/050013 WO2016091236A1 (en) 2014-12-09 2015-12-02 6-aryl-9-glycosylpurines and use thereof

Publications (1)

Publication Number Publication Date
PL3229772T3 true PL3229772T3 (pl) 2020-11-02

Family

ID=54251269

Family Applications (1)

Application Number Title Priority Date Filing Date
PL15816356T PL3229772T3 (pl) 2014-12-09 2015-12-02 6-arylo-9-glikozylopuryny i ich zastosowanie

Country Status (6)

Country Link
US (2) US10100077B2 (pl)
EP (2) EP3229771B1 (pl)
CZ (1) CZ308881B6 (pl)
PL (1) PL3229772T3 (pl)
SG (1) SG11201704019TA (pl)
WO (2) WO2016091235A1 (pl)

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1063952A (en) * 1964-03-17 1967-04-05 Takeda Chemical Industries Ltd A process for producing purine-ribosides
CA989341A (en) * 1971-02-26 1976-05-18 Kyowa Hakko Kogyo Co. Process for producing ribosides of heterocyclic organic bases by fermentation
UA55406C2 (uk) 1996-03-15 2003-04-15 Новартіс Аг Гербіцидна синергічна композиція і спосіб боротьби з бур'янами
US6294522B1 (en) * 1999-12-03 2001-09-25 Cv Therapeutics, Inc. N6 heterocyclic 8-modified adenosine derivatives
CZ294538B6 (cs) * 2002-12-30 2005-01-12 Ústav Experimentální Botaniky Akademie Vědčeské Re Substituční deriváty N6-benzyladenosinu, způsob jejich přípravy, jejich použití pro přípravu léčiv, kosmetických přípravků a růstových regulátorů, farmaceutické přípravky, kosmetické přípravky a růstové regulátory tyto sloučeniny obsahující
WO2005030152A1 (ja) * 2003-09-30 2005-04-07 Lion Corporation 養育毛剤組成物
US7893227B2 (en) 2006-12-05 2011-02-22 Lasergen, Inc. 3′-OH unblocked nucleotides and nucleosides base modified with non-cleavable, terminating groups and methods for their use in DNA sequencing
CZ2009298A3 (cs) * 2009-05-14 2010-11-24 Univerzita Palackého v Olomouci Substituované 6-benzylaminopurin ribosidy, jejich použití a farmaceutický prípravek tyto slouceniny obsahující
JP2013513551A (ja) * 2009-12-10 2013-04-22 中国医学科学院葯物研究所 Ｎ６−置換アデノシン誘導体とｎ６−置換アデニン誘導体の鎮静、催眠，抗うつ，抗痙攣，抗てんかん，抗パーキンソン病と認知証予防・治療の用途
EP2657246B1 (en) 2010-10-27 2016-04-13 Public University Corporation Yokohama City University Modulator of activity of adenylate cyclase
US20120164641A1 (en) 2010-12-22 2012-06-28 Roche Molecular Systems, Inc. Methods and Compositions for Detecting Mutation in the Human Epidermal Growth Factor Receptor Gene

Also Published As

Publication number Publication date
US20170326168A1 (en) 2017-11-16
EP3229772A1 (en) 2017-10-18
US10100077B2 (en) 2018-10-16
WO2016091235A1 (en) 2016-06-16
US20170334943A1 (en) 2017-11-23
WO2016091236A1 (en) 2016-06-16
US10550144B2 (en) 2020-02-04
EP3229771A1 (en) 2017-10-18
CZ2014875A3 (cs) 2016-06-22
SG11201704019TA (en) 2017-06-29
CZ308881B6 (cs) 2021-08-04
EP3229771B1 (en) 2024-04-03
EP3229772B1 (en) 2020-04-29

Similar Documents

Publication Publication Date Title
IL252216B (en) Difluoromethyl-aminopyridines and difluoromethyl-aminopyrimidines
HK1231471A1 (zh) -雜芳氧基-和 芳氧基-喹啉- -甲酰胺及其用途
GB201411197D0 (en) Composition and use thereof
PL3015526T3 (pl) Kompozycja na bazie wodorofluoroolefiny i jej zastosowanie
HUE044571T2 (hu) Módosított ciklopentapeptidek és alkalmazásaik
GB201401617D0 (en) Novel combination and use
HK1223969A1 (zh) 試劑盒及其用途
IL247315A0 (en) Anti-acth antibodies and their uses
HK1243950A1 (zh) 新型組合物和用途
PL3194656T3 (pl) Uchwyt listwy uszczelniającej oraz jego zastosowanie
SG11201704473WA (en) New methods and uses
ZA201704105B (en) Refractories and use thereof
HK1243077A1 (zh) 呱啶基吡唑並嘧啶酮及其用途
GB201411196D0 (en) Composition and use thereof
GB201408091D0 (en) Methods and uses
GB201620840D0 (en) Catalyst and use thereof
GB201420805D0 (en) Ligatures and use thereof
GB2545167B (en) Cloches and use thereof
PL3229772T3 (pl) 6-arylo-9-glikozylopuryny i ich zastosowanie
PT2923578T (pt) Método para a produção de um produto alimentar
GB201500278D0 (en) Novel combination and use
GB201416086D0 (en) Methods and uses
GB201416073D0 (en) Methods and uses
GB201413411D0 (en) Novel compounds and their use
GB201404728D0 (en) Disc-over incorporating disc-heads and disc-earning