PL3152226T3 - Modyfikowane cyklopentapeptydy i ich zastosowania - Google Patents

Modyfikowane cyklopentapeptydy i ich zastosowania

Info

Publication number
PL3152226T3
PL3152226T3 PL14733548T PL14733548T PL3152226T3 PL 3152226 T3 PL3152226 T3 PL 3152226T3 PL 14733548 T PL14733548 T PL 14733548T PL 14733548 T PL14733548 T PL 14733548T PL 3152226 T3 PL3152226 T3 PL 3152226T3
Authority
PL
Poland
Prior art keywords
cyclopentapeptides
modified
modified cyclopentapeptides
Prior art date
Application number
PL14733548T
Other languages
English (en)
Inventor
Hans-Jürgen Wester
Margret Schottelius
Theresa Osl
Andreas Poschenrieder
Marina Willibald
Original Assignee
Univ Muenchen Tech
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Muenchen Tech filed Critical Univ Muenchen Tech
Publication of PL3152226T3 publication Critical patent/PL3152226T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/082—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins the peptide being a RGD-containing peptide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Epidemiology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PL14733548T 2014-06-06 2014-06-06 Modyfikowane cyklopentapeptydy i ich zastosowania PL3152226T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP14733548.3A EP3152226B1 (en) 2014-06-06 2014-06-06 Modified cyclopentapeptides and uses thereof
PCT/EP2014/061875 WO2015185162A1 (en) 2014-06-06 2014-06-06 Modified cyclopentapeptides and uses thereof

Publications (1)

Publication Number Publication Date
PL3152226T3 true PL3152226T3 (pl) 2019-10-31

Family

ID=51022816

Family Applications (1)

Application Number Title Priority Date Filing Date
PL14733548T PL3152226T3 (pl) 2014-06-06 2014-06-06 Modyfikowane cyklopentapeptydy i ich zastosowania

Country Status (7)

Country Link
US (1) US10919938B2 (pl)
EP (1) EP3152226B1 (pl)
CN (1) CN106573959B (pl)
AU (1) AU2014396468B2 (pl)
HU (1) HUE044571T2 (pl)
PL (1) PL3152226T3 (pl)
WO (1) WO2015185162A1 (pl)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUE054006T2 (hu) 2011-12-28 2021-08-30 Chugai Pharmaceutical Co Ltd Eljárás peptid vegyület ciklizálására
US10815489B2 (en) 2015-03-13 2020-10-27 Chugai Seiyaku Kabushiki Kaisha Modified aminoacyl-tRNA synthetase and use thereof
CN109789207B (zh) * 2016-07-25 2022-11-18 威斯康星校友研究基金会 用于原位免疫调节的癌症疫苗接种的靶向放射治疗螯合物
US12391971B2 (en) 2017-01-31 2025-08-19 Chugai Seiyaku Kabushiki Kaisha Method for synthesizing peptides in cell-free translation system
KR102744693B1 (ko) * 2017-06-09 2024-12-18 추가이 세이야쿠 가부시키가이샤 N-치환 아미노산을 포함하는 펩타이드의 합성 방법
KR20200043970A (ko) * 2017-09-05 2020-04-28 메인라인 바이오사이언스 고친화성 cxcr4 선택적 결합 콘쥬게이트 및 그 사용 방법
US10639379B2 (en) * 2017-09-05 2020-05-05 Mainline Biosciences Llc High affinity CXCR4 selective binding conjugate and method for using the same
US11123437B2 (en) * 2017-09-05 2021-09-21 Mainline Biosciences, Inc. Selective CXCR4 binding peptide conjugate and methods for making and using the same
CN111479819B (zh) 2017-12-15 2024-06-14 中外制药株式会社 制备肽的方法和处理碱的方法
JP2021165234A (ja) * 2018-07-03 2021-10-14 富士フイルム富山化学株式会社 Ｃｘｃｒ４結合性化合物もしくはその塩またはそれらと金属との錯体
EA202190755A1 (ru) 2018-09-12 2021-06-11 Технише Универзитет Мюнхен Агенты для терапии и диагностики рака
EP3849997B1 (en) * 2018-09-12 2024-05-01 Technische Universität München Cxcr4-targeted diagnostic and therapeutic agents with reduced species selectivity
KR102841441B1 (ko) 2018-11-07 2025-07-31 추가이 세이야쿠 가부시키가이샤 O-치환 세린 유도체의 제조 방법
CN113056475B (zh) 2018-11-30 2024-09-24 中外制药株式会社 用于肽化合物或酰胺化合物的脱保护方法和在固相反应中的树脂脱除方法以及用于生产肽化合物的方法
JP7472101B2 (ja) 2019-03-15 2024-04-22 中外製薬株式会社 芳香族アミノ酸誘導体の製造方法
BR112022007535A2 (pt) 2019-11-07 2022-07-12 Chugai Pharmaceutical Co Ltd Composto peptídico cíclico tendo ação inibitória de kras
EP4055020A4 (en) * 2019-11-08 2024-01-10 The University of Queensland RADIOLABELED TARGETING LIGANDS
EP4097120A4 (en) * 2020-01-26 2024-05-01 Mainline Biosciences (Shanghai) Co., Ltd. ISOTOPE-LABELED CXCR4 SELECTIVELY BINDING PEPTIDE CONJUGATE AND METHODS OF MAKING AND USE THEREOF
WO2022115778A1 (en) 2020-11-30 2022-06-02 Rayzebio, Inc. Radiopharmaceutical conjugate compositions and uses thereof
EP4043041A1 (en) 2021-02-15 2022-08-17 Technische Universität München Cxcr4-ligands for diagnostic and therapeutic use and precursors thereof
CN114163499B (zh) * 2021-11-11 2024-08-02 浙江大学 一种神经钙粘蛋白抑制剂及其制备方法和应用

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1989007456A1 (en) 1988-02-09 1989-08-24 Mallinckrodt, Inc. Method of preparing a metal-radionuclide-labelled protein
CA2247430A1 (en) 1996-02-27 1997-09-04 Mallinckrodt Medical, Inc. Use of labelled cck-b receptor ligands for the detection and localization of malignant human tumors
NO20004795D0 (no) * 2000-09-26 2000-09-26 Nycomed Imaging As Peptidbaserte forbindelser
WO2002042259A2 (en) 2000-11-27 2002-05-30 University Of Maryland, Baltimore Methods of synthesizing and using derivatives of [2-(2-aminoethoxy)ethoxy] acetic acid
ATE427125T1 (de) * 2001-04-23 2009-04-15 Mallinckrodt Inc Tc und re markierte radioaktive glycosylierte octreotid-derivate
US20060029544A1 (en) * 2004-08-06 2006-02-09 The Regents Of The University Of California Office Of Technology Transfer Receptor-binding cyclic peptides and methods of use
GB0603901D0 (en) * 2006-02-27 2006-04-05 Mallinckrodt Inc Cancer imaging and treatment
US8628750B2 (en) * 2006-02-27 2014-01-14 Technische Universitat Munchen Cancer imaging and treatment
US8080659B2 (en) 2006-07-11 2011-12-20 Emory University CXCR4 antagonists including diazine and triazine structures for the treatment of medical disorders
GB0716897D0 (en) 2007-08-30 2007-10-10 Univ Muenchen Tech Cancer imaging and treatment
EP2100900A1 (en) 2008-03-07 2009-09-16 Universitätsspital Basel Bombesin analog peptide antagonist conjugates
US8133472B2 (en) 2008-04-30 2012-03-13 Siemens Medical Solutions Usa, Inc. Cyclopeptides containing RGD mimetics as imaging markers for integrins
EP2380596A1 (en) * 2010-04-20 2011-10-26 Technische Universität München Cyclopentapeptide derivatives and uses thereof
EP2380597A1 (en) * 2010-04-20 2011-10-26 Technische Universität München Cyclopeptide derivatives and uses thereof

Also Published As

Publication number Publication date
AU2014396468B2 (en) 2019-02-21
EP3152226B1 (en) 2019-05-29
AU2014396468A1 (en) 2016-12-01
US20180037608A1 (en) 2018-02-08
HUE044571T2 (hu) 2019-11-28
WO2015185162A1 (en) 2015-12-10
US10919938B2 (en) 2021-02-16
CN106573959B (zh) 2022-03-25
EP3152226A1 (en) 2017-04-12
CN106573959A (zh) 2017-04-19

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