SG10202012179RA - Arylmethoxy isoindoline derivatives and compositions comprising and methods of using the same - Google Patents

Arylmethoxy isoindoline derivatives and compositions comprising and methods of using the same

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Publication number
SG10202012179RA
SG10202012179RA SG10202012179RA SG10202012179RA SG10202012179RA SG 10202012179R A SG10202012179R A SG 10202012179RA SG 10202012179R A SG10202012179R A SG 10202012179RA SG 10202012179R A SG10202012179R A SG 10202012179RA SG 10202012179R A SG10202012179R A SG 10202012179RA
Authority
SG
Singapore
Prior art keywords
compositions
methods
same
isoindoline derivatives
arylmethoxy isoindoline
Prior art date
Application number
SG10202012179RA
Other languages
English (en)
Inventor
Hon-Wah Man
George Muller
Alexander Ruchelman
Ehab Khalil
Roger Chen
Weihong Zhang
Original Assignee
Celgene Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Celgene Corp filed Critical Celgene Corp
Publication of SG10202012179RA publication Critical patent/SG10202012179RA/en

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    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4412—Non condensed pyridines; Hydrogenated derivatives thereof having oxo groups directly attached to the heterocyclic ring
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    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
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    • C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
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    • C07D498/08—Bridged systems

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  • Chemical & Material Sciences (AREA)
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  • Animal Behavior & Ethology (AREA)
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  • Immunology (AREA)
  • Neurology (AREA)
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  • Biomedical Technology (AREA)
  • Diabetes (AREA)
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  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Vascular Medicine (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Pain & Pain Management (AREA)
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  • Tropical Medicine & Parasitology (AREA)
  • Epidemiology (AREA)
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  • Pulmonology (AREA)
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  • AIDS & HIV (AREA)
  • Urology & Nephrology (AREA)
  • Dermatology (AREA)
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SG10202012179RA 2010-02-11 2011-02-10 Arylmethoxy isoindoline derivatives and compositions comprising and methods of using the same SG10202012179RA (en)

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US30361810P 2010-02-11 2010-02-11

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SG10202012179RA SG10202012179RA (en) 2010-02-11 2011-02-10 Arylmethoxy isoindoline derivatives and compositions comprising and methods of using the same
SG10201501062SA SG10201501062SA (en) 2010-02-11 2011-02-10 Arylmethoxy isoindoline derivatives and compositions comprising and methods of using the same
SG2012059259A SG183257A1 (en) 2010-02-11 2011-02-10 Arylmethoxy isoindoline derivatives and compositions comprising and methods of using the same

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SG2012059259A SG183257A1 (en) 2010-02-11 2011-02-10 Arylmethoxy isoindoline derivatives and compositions comprising and methods of using the same

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US (8) US8518972B2 (pl)
EP (6) EP3202460B1 (pl)
JP (5) JP2013519675A (pl)
KR (2) KR101812356B1 (pl)
CN (2) CN104693193B (pl)
AR (1) AR081058A1 (pl)
AU (1) AU2011215877C1 (pl)
CA (1) CA2787823C (pl)
CO (1) CO6571916A2 (pl)
CR (1) CR20120414A (pl)
CY (3) CY1119177T1 (pl)
DK (3) DK3202460T3 (pl)
EC (1) ECSP12012098A (pl)
ES (5) ES2730763T3 (pl)
HR (3) HRP20171078T1 (pl)
HU (3) HUE042011T2 (pl)
IL (2) IL220992A (pl)
LT (3) LT3202460T (pl)
ME (2) ME03441B (pl)
MX (3) MX2012009237A (pl)
NI (1) NI201200132A (pl)
NZ (3) NZ717149A (pl)
PH (1) PH12014501082B1 (pl)
PL (3) PL3202460T3 (pl)
PT (3) PT3202460T (pl)
RS (3) RS59275B1 (pl)
RU (1) RU2567753C2 (pl)
SG (3) SG10202012179RA (pl)
SI (3) SI3202460T1 (pl)
TR (1) TR201903027T4 (pl)
UA (2) UA114856C2 (pl)
WO (1) WO2011100380A1 (pl)

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CN104718202B (zh) 2012-08-09 2018-11-20 细胞基因公司 用于制备(s)-3-(4-((4-(吗啉基甲基)苄基)氧基)-1-氧代异吲哚啉-2-基)哌啶-2,6-二酮及其可药用形式的方法
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