MX367522B - Derivados de arilmetoxi isoindolina y composiciones que los comprenden y métodos para utilizar los mismos. - Google Patents

Derivados de arilmetoxi isoindolina y composiciones que los comprenden y métodos para utilizar los mismos.

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Publication number
MX367522B
MX367522B MX2016001880A MX2016001880A MX367522B MX 367522 B MX367522 B MX 367522B MX 2016001880 A MX2016001880 A MX 2016001880A MX 2016001880 A MX2016001880 A MX 2016001880A MX 367522 B MX367522 B MX 367522B
Authority
MX
Mexico
Prior art keywords
methods
compositions
same
compounds
isoindoline derivatives
Prior art date
Application number
MX2016001880A
Other languages
English (en)
Inventor
W Muller George
Man Hon-Wah
Ruchelman Alexander
M Khalil Ehab
Zhang Weihong
Shen- Chu Chen Roger
Original Assignee
Celgene Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Celgene Corp filed Critical Celgene Corp
Publication of MX367522B publication Critical patent/MX367522B/es

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    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4412—Non condensed pyridines; Hydrogenated derivatives thereof having oxo groups directly attached to the heterocyclic ring
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    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
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    • C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
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Abstract

Se proporcionan compuestos de 4' -arilmetoxi isoindolina, y sales, solvatos, clatratos, estereoisómeros y profármacos farmacéuticamente aceptables de los mismos. Se describen los métodos de uso, y las composiciones farmacéuticas de estos compuestos. Los compuestos son derivados de hidroxi talidomida activa contra el cáncer.
MX2016001880A 2010-02-11 2011-02-10 Derivados de arilmetoxi isoindolina y composiciones que los comprenden y métodos para utilizar los mismos. MX367522B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US30361810P 2010-02-11 2010-02-11
PCT/US2011/024269 WO2011100380A1 (en) 2010-02-11 2011-02-10 Arylmethoxy isoindoline derivatives and compositions comprising and methods of using the same

Publications (1)

Publication Number Publication Date
MX367522B true MX367522B (es) 2019-08-26

Family

ID=43708752

Family Applications (3)

Application Number Title Priority Date Filing Date
MX2013011071A MX337169B (es) 2010-02-11 2011-02-10 Derivados de arilmetoxi isoindolina y composiciones que los comprenden y metodos para utilizar los mismos.
MX2016001880A MX367522B (es) 2010-02-11 2011-02-10 Derivados de arilmetoxi isoindolina y composiciones que los comprenden y métodos para utilizar los mismos.
MX2012009237A MX2012009237A (es) 2010-02-11 2011-02-10 Derivados de arilmetoxi isoindolina y composiciones que los comprenden y metodos para utilizar los mismos.

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MX2013011071A MX337169B (es) 2010-02-11 2011-02-10 Derivados de arilmetoxi isoindolina y composiciones que los comprenden y metodos para utilizar los mismos.

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MX2012009237A MX2012009237A (es) 2010-02-11 2011-02-10 Derivados de arilmetoxi isoindolina y composiciones que los comprenden y metodos para utilizar los mismos.

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US (8) US8518972B2 (es)
EP (6) EP4289838A3 (es)
JP (5) JP2013519675A (es)
KR (2) KR101812356B1 (es)
CN (2) CN102822165B (es)
AR (1) AR081058A1 (es)
AU (1) AU2011215877C1 (es)
CA (1) CA2787823C (es)
CO (1) CO6571916A2 (es)
CR (1) CR20120414A (es)
CY (3) CY1119177T1 (es)
DK (3) DK2536706T3 (es)
EC (1) ECSP12012098A (es)
ES (5) ES2956743T3 (es)
HR (3) HRP20171078T1 (es)
HU (3) HUE044652T2 (es)
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LT (3) LT3202461T (es)
ME (2) ME02766B (es)
MX (3) MX337169B (es)
NI (1) NI201200132A (es)
NZ (3) NZ601289A (es)
PH (1) PH12014501082B1 (es)
PL (3) PL2536706T3 (es)
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SI (3) SI3202460T1 (es)
TR (1) TR201903027T4 (es)
UA (2) UA114856C2 (es)
WO (1) WO2011100380A1 (es)

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US9090585B2 (en) 2011-03-28 2015-07-28 Deuterx, Llc 2,6-dioxo-3-deutero-piperdin-3-yl-isoindoline compounds
KR20140024914A (ko) 2011-04-29 2014-03-03 셀진 코포레이션 예측인자로 세레브론을 사용하는 암 및 염증성 질환의 치료를 위한 방법
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