MX346608B - Compuestos de isoindol 5-sustituidos. - Google Patents
Compuestos de isoindol 5-sustituidos.Info
- Publication number
- MX346608B MX346608B MX2016008319A MX2016008319A MX346608B MX 346608 B MX346608 B MX 346608B MX 2016008319 A MX2016008319 A MX 2016008319A MX 2016008319 A MX2016008319 A MX 2016008319A MX 346608 B MX346608 B MX 346608B
- Authority
- MX
- Mexico
- Prior art keywords
- substituted isoindoline
- isoindoline compounds
- compounds
- substituted
- prodrugs
- Prior art date
Links
- -1 5-substituted isoindoline compounds Chemical class 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000000651 prodrug Substances 0.000 abstract 1
- 229940002612 prodrug Drugs 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
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- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
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- A61K31/47—Quinolines; Isoquinolines
- A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
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- A61K31/47—Quinolines; Isoquinolines
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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Abstract
La invención se refiere a compuestos de isoindolina 5-sustituida y las sales, solvatos, esteroisómeros y profármacos de los mismos aceptables farmacéuticamente. Se describen métodos de uso y composiciones farmacéuticas de estos compuestos.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US12/130,445 US8877780B2 (en) | 2006-08-30 | 2008-05-30 | 5-substituted isoindoline compounds |
PCT/US2009/003258 WO2009145899A1 (en) | 2008-05-30 | 2009-05-28 | 5-substituted isoindoline compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
MX346608B true MX346608B (es) | 2017-03-27 |
Family
ID=41048037
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2010013107A MX2010013107A (es) | 2008-05-30 | 2009-05-28 | Compuestos de isoindol 5-sustiuidos. |
MX2014002740A MX341197B (es) | 2008-05-30 | 2009-05-28 | Compuestos de isoindol 5 - sustituidos. |
MX2016008319A MX346608B (es) | 2008-05-30 | 2009-05-28 | Compuestos de isoindol 5-sustituidos. |
Family Applications Before (2)
Application Number | Title | Priority Date | Filing Date |
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US8877780B2 (en) * | 2006-08-30 | 2014-11-04 | Celgene Corporation | 5-substituted isoindoline compounds |
WO2008039489A2 (en) * | 2006-09-26 | 2008-04-03 | Celgene Corporation | 5-substituted quinazolinone derivatives as antitumor agents |
WO2009085234A2 (en) * | 2007-12-20 | 2009-07-09 | Signal Pharmaceuticals, Inc. | Use of micro-rna as a biomarker of immunomodulatory drug activity |
WO2009143899A1 (en) | 2008-05-30 | 2009-12-03 | Gva Consultants Ab | Mating |
KR101696938B1 (ko) * | 2008-10-29 | 2017-01-16 | 셀진 코포레이션 | 암의 치료에 사용하기 위한 이소인돌린 화합물 |
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