MX346608B - Compuestos de isoindol 5-sustituidos. - Google Patents

Compuestos de isoindol 5-sustituidos.

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Publication number
MX346608B
MX346608B MX2016008319A MX2016008319A MX346608B MX 346608 B MX346608 B MX 346608B MX 2016008319 A MX2016008319 A MX 2016008319A MX 2016008319 A MX2016008319 A MX 2016008319A MX 346608 B MX346608 B MX 346608B
Authority
MX
Mexico
Prior art keywords
substituted isoindoline
isoindoline compounds
compounds
substituted
prodrugs
Prior art date
Application number
MX2016008319A
Other languages
English (en)
Inventor
W Muller George
Man Hon-Wah
M Khalil Ehab
Zhang Weihong
L Ruchelman Alexander
S C Chen Roger
Original Assignee
Celgene Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Celgene Corp filed Critical Celgene Corp
Publication of MX346608B publication Critical patent/MX346608B/es

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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4523Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • AHUMAN NECESSITIES
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    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4523Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4545Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
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    • A61K31/47Quinolines; Isoquinolines
    • A61K31/4709Non-condensed quinolines and containing further heterocyclic rings
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Abstract

La invención se refiere a compuestos de isoindolina 5-sustituida y las sales, solvatos, esteroisómeros y profármacos de los mismos aceptables farmacéuticamente. Se describen métodos de uso y composiciones farmacéuticas de estos compuestos.
MX2016008319A 2008-05-30 2009-05-28 Compuestos de isoindol 5-sustituidos. MX346608B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12/130,445 US8877780B2 (en) 2006-08-30 2008-05-30 5-substituted isoindoline compounds
PCT/US2009/003258 WO2009145899A1 (en) 2008-05-30 2009-05-28 5-substituted isoindoline compounds

Publications (1)

Publication Number Publication Date
MX346608B true MX346608B (es) 2017-03-27

Family

ID=41048037

Family Applications (3)

Application Number Title Priority Date Filing Date
MX2010013107A MX2010013107A (es) 2008-05-30 2009-05-28 Compuestos de isoindol 5-sustiuidos.
MX2014002740A MX341197B (es) 2008-05-30 2009-05-28 Compuestos de isoindol 5 - sustituidos.
MX2016008319A MX346608B (es) 2008-05-30 2009-05-28 Compuestos de isoindol 5-sustituidos.

Family Applications Before (2)

Application Number Title Priority Date Filing Date
MX2010013107A MX2010013107A (es) 2008-05-30 2009-05-28 Compuestos de isoindol 5-sustiuidos.
MX2014002740A MX341197B (es) 2008-05-30 2009-05-28 Compuestos de isoindol 5 - sustituidos.

Country Status (19)

Country Link
US (3) US8877780B2 (es)
EP (4) EP2291365B1 (es)
JP (2) JP5990379B2 (es)
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CN (1) CN102112463A (es)
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