PL3202460T3 - Pochodne arylometoksyizoindoliny i zawierające je kompozycje oraz sposoby ich zastosowania - Google Patents

Pochodne arylometoksyizoindoliny i zawierające je kompozycje oraz sposoby ich zastosowania

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Publication number
PL3202460T3
PL3202460T3 PL17157170T PL17157170T PL3202460T3 PL 3202460 T3 PL3202460 T3 PL 3202460T3 PL 17157170 T PL17157170 T PL 17157170T PL 17157170 T PL17157170 T PL 17157170T PL 3202460 T3 PL3202460 T3 PL 3202460T3
Authority
PL
Poland
Prior art keywords
compositions
methods
same
isoindoline derivatives
arylmethoxy isoindoline
Prior art date
Application number
PL17157170T
Other languages
English (en)
Inventor
Hon-Wah Man
George W. Muller
Alexander L Ruchelman
Ehab M. Khalil
Roger Shen-Chu Chen
Weihong Zhang
Original Assignee
Celgene Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Celgene Corporation filed Critical Celgene Corporation
Publication of PL3202460T3 publication Critical patent/PL3202460T3/pl

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    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4412—Non condensed pyridines; Hydrogenated derivatives thereof having oxo groups directly attached to the heterocyclic ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
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    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
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    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
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    • C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
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    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10—Spiro-condensed systems
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    • C07D493/04—Ortho-condensed systems
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    • C07D495/04—Ortho-condensed systems
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    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/08—Bridged systems
PL17157170T 2010-02-11 2011-02-10 Pochodne arylometoksyizoindoliny i zawierające je kompozycje oraz sposoby ich zastosowania PL3202460T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US30361810P 2010-02-11 2010-02-11
EP11704156.6A EP2536706B1 (en) 2010-02-11 2011-02-10 Arylmethoxy isoindoline derivatives and compositions comprising and methods of using the same
EP17157170.6A EP3202460B1 (en) 2010-02-11 2011-02-10 Arylmethoxy isoindoline derivatives and compositions comprising and methods of using the same
PCT/US2011/024269 WO2011100380A1 (en) 2010-02-11 2011-02-10 Arylmethoxy isoindoline derivatives and compositions comprising and methods of using the same

Publications (1)

Publication Number Publication Date
PL3202460T3 true PL3202460T3 (pl) 2019-12-31

Family

ID=43708752

Family Applications (3)

Application Number Title Priority Date Filing Date
PL17157178T PL3202461T3 (pl) 2010-02-11 2011-02-10 Pochodne arylometoksyizoindoliny i zawierające je kompozycje oraz sposoby ich zastosowania
PL11704156T PL2536706T3 (pl) 2010-02-11 2011-02-10 Pochodne arylometoksyizoindoliny i zawierające je kompozycje oraz sposoby ich zastosowania
PL17157170T PL3202460T3 (pl) 2010-02-11 2011-02-10 Pochodne arylometoksyizoindoliny i zawierające je kompozycje oraz sposoby ich zastosowania

Family Applications Before (2)

Application Number Title Priority Date Filing Date
PL17157178T PL3202461T3 (pl) 2010-02-11 2011-02-10 Pochodne arylometoksyizoindoliny i zawierające je kompozycje oraz sposoby ich zastosowania
PL11704156T PL2536706T3 (pl) 2010-02-11 2011-02-10 Pochodne arylometoksyizoindoliny i zawierające je kompozycje oraz sposoby ich zastosowania

Country Status (32)

Country Link
US (8) US8518972B2 (pl)
EP (6) EP3202461B1 (pl)
JP (5) JP2013519675A (pl)
KR (2) KR101931468B1 (pl)
CN (2) CN102822165B (pl)
AR (1) AR081058A1 (pl)
AU (1) AU2011215877C1 (pl)
CA (1) CA2787823C (pl)
CO (1) CO6571916A2 (pl)
CR (1) CR20120414A (pl)
CY (3) CY1119177T1 (pl)
DK (3) DK2536706T3 (pl)
EC (1) ECSP12012098A (pl)
ES (5) ES2638517T3 (pl)
HR (3) HRP20171078T1 (pl)
HU (3) HUE042011T2 (pl)
IL (2) IL220992A (pl)
LT (3) LT2536706T (pl)
ME (2) ME02766B (pl)
MX (3) MX367522B (pl)
NI (1) NI201200132A (pl)
NZ (3) NZ717149A (pl)
PH (1) PH12014501082A1 (pl)
PL (3) PL3202461T3 (pl)
PT (3) PT2536706T (pl)
RS (3) RS59275B1 (pl)
RU (1) RU2567753C2 (pl)
SG (3) SG10201501062SA (pl)
SI (3) SI2536706T1 (pl)
TR (1) TR201903027T4 (pl)
UA (2) UA115220C2 (pl)
WO (1) WO2011100380A1 (pl)

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SI2536706T1 (sl) 2010-02-11 2017-10-30 Celgene Corporation Derivati arilmetoksi izoindolina in sestavki,ki jih vsebujejo ter metode uporabe le-teh
CA2867134C (en) 2011-03-28 2019-05-07 Sheila Dewitt 2',6'-dioxo-3'-deutero-piperdin-3-yl-isoindoline compounds
KR20140024914A (ko) 2011-04-29 2014-03-03 셀진 코포레이션 예측인자로 세레브론을 사용하는 암 및 염증성 질환의 치료를 위한 방법
JP6318152B2 (ja) 2012-06-29 2018-04-25 セルジーン コーポレイション セレブロン関連タンパク質を利用して薬物効能を決定する方法
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TWI653977B (zh) * 2012-08-09 2019-03-21 美商西建公司 利用３－（４－（（４－（嗎啉基甲基）苄基）氧基）－１－氧異吲哚啉－２－基）六氫吡啶－２，６－二酮治療癌症之方法
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UA114521C2 (uk) 2012-08-09 2017-06-26 Селджин Корпорейшн Солі і тверді форми (s)-3-(4-((4-морфолінометил)-бензил)оксі)-1-оксоізоіндолін-2-іл)-піперидин-2,6-діону і композиції, які їх включають, і способи їхнього застосування
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