NO323104B1 - Analoger av humant erytropoietin, DNA-sekvenser som koder for disse, eukaryot vertscelle transfektert med DNA-sekvensene, preparat som omfatter analogene, anvendelse av analogene til okning av hematokritt, og fremgangsmate for fremstilling av analogene. - Google Patents
Analoger av humant erytropoietin, DNA-sekvenser som koder for disse, eukaryot vertscelle transfektert med DNA-sekvensene, preparat som omfatter analogene, anvendelse av analogene til okning av hematokritt, og fremgangsmate for fremstilling av analogene. Download PDFInfo
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- NO323104B1 NO323104B1 NO19951445A NO951445A NO323104B1 NO 323104 B1 NO323104 B1 NO 323104B1 NO 19951445 A NO19951445 A NO 19951445A NO 951445 A NO951445 A NO 951445A NO 323104 B1 NO323104 B1 NO 323104B1
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- erythropoietin
- analogue
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/505—Erythropoietin [EPO]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Toxicology (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicinal Preparation (AREA)
- Preparation Of Fruits And Vegetables (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
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US10801693A | 1993-08-17 | 1993-08-17 | |
PCT/US1994/009257 WO1995005465A1 (en) | 1993-08-17 | 1994-08-16 | Erythropoietin analogs |
Publications (3)
Publication Number | Publication Date |
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NO951445D0 NO951445D0 (no) | 1995-04-12 |
NO951445L NO951445L (no) | 1995-06-16 |
NO323104B1 true NO323104B1 (no) | 2007-01-02 |
Family
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Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO19951445A NO323104B1 (no) | 1993-08-17 | 1995-04-12 | Analoger av humant erytropoietin, DNA-sekvenser som koder for disse, eukaryot vertscelle transfektert med DNA-sekvensene, preparat som omfatter analogene, anvendelse av analogene til okning av hematokritt, og fremgangsmate for fremstilling av analogene. |
NO2007008C NO2007008I2 (no) | 1993-08-17 | 2007-06-29 | Analoger av humant erytropoietin,DNA-sekvenser somkoder for disse, eukaryot vertscelle transfektert med DNA-sekvensene, preparat som omfatter analoge ne, anvendelse av analogene til økning av hematokritt, og fremgangsmåte for fremstilling av analogene. |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
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NO2007008C NO2007008I2 (no) | 1993-08-17 | 2007-06-29 | Analoger av humant erytropoietin,DNA-sekvenser somkoder for disse, eukaryot vertscelle transfektert med DNA-sekvensene, preparat som omfatter analoge ne, anvendelse av analogene til økning av hematokritt, og fremgangsmåte for fremstilling av analogene. |
Country Status (27)
Country | Link |
---|---|
EP (1) | EP0640619B2 (zh) |
JP (3) | JP2938572B2 (zh) |
KR (2) | KR100328769B1 (zh) |
CN (1) | CN1057534C (zh) |
AT (1) | ATE155796T1 (zh) |
AU (1) | AU677097B2 (zh) |
CA (1) | CA2147124C (zh) |
CZ (3) | CZ291229B6 (zh) |
DE (2) | DE69404401T3 (zh) |
DK (1) | DK0640619T4 (zh) |
ES (1) | ES2105442T5 (zh) |
FI (1) | FI117136B (zh) |
GR (1) | GR3024815T3 (zh) |
HK (1) | HK1001589A1 (zh) |
HU (1) | HU220334B (zh) |
IL (4) | IL110669A (zh) |
LU (1) | LU90850I2 (zh) |
LV (1) | LV10972B (zh) |
NL (1) | NL300075I2 (zh) |
NO (2) | NO323104B1 (zh) |
NZ (1) | NZ273134A (zh) |
RU (1) | RU2159814C2 (zh) |
SI (1) | SI0640619T2 (zh) |
SK (1) | SK282003B6 (zh) |
UA (1) | UA49793C2 (zh) |
WO (1) | WO1995005465A1 (zh) |
ZA (1) | ZA946122B (zh) |
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US7217689B1 (en) | 1989-10-13 | 2007-05-15 | Amgen Inc. | Glycosylation analogs of erythropoietin |
US5614184A (en) * | 1992-07-28 | 1997-03-25 | New England Deaconess Hospital | Recombinant human erythropoietin mutants and therapeutic methods employing them |
US5989538A (en) * | 1995-02-15 | 1999-11-23 | Amgen Inc. | Mpl ligand analogs |
US5696250A (en) * | 1995-02-15 | 1997-12-09 | Amgen Inc. | DNA encoding megakaryocyte growth and development factor analogs |
WO1997013783A1 (en) * | 1995-10-09 | 1997-04-17 | Pharmacia & Upjohn Company | An acceptor polypeptide for an n-acetylgalactosaminyltransferase |
KR100400637B1 (ko) * | 1996-02-06 | 2004-03-10 | 씨제이 주식회사 | 생물학적으로유용한펩타이드 |
CA2246768C (en) | 1996-03-14 | 2013-12-31 | Genentech, Inc. | Uses of gdnf and gdnf receptor |
US5952226A (en) * | 1996-11-05 | 1999-09-14 | Modex Therapeutiques | Hypoxia responsive EPO producing cells |
ES2208798T3 (es) * | 1997-09-01 | 2004-06-16 | Aventis Pharma Deutschland Gmbh | Eritropoyetina humana recombinante con un perfil de glicosilacion ventajoso. |
EP1037927B1 (en) | 1997-12-08 | 2004-05-19 | Lexigen Pharmaceuticals Corp. | Heterodimeric fusion proteins useful for targeted immune therapy and general immune stimulation |
EP1088084B1 (en) | 1998-06-15 | 2006-09-13 | GTC Biotherapeutics, Inc. | Erythropoietin analog-human serum albumin fusion protein |
SI1813624T1 (sl) * | 1998-10-23 | 2010-12-31 | Amgen Inc | Postopki in sestavki za prepeäśevanje in zdravljenje anemije |
US7304150B1 (en) | 1998-10-23 | 2007-12-04 | Amgen Inc. | Methods and compositions for the prevention and treatment of anemia |
DE19857609A1 (de) | 1998-12-14 | 2000-06-15 | Hannelore Ehrenreich | Verwendung von Erythropoietin zur Behandlung von cerebralen Ischämien des Menschen |
JP4841037B2 (ja) * | 1999-02-12 | 2011-12-21 | アムジエン・インコーポレーテツド | グリコシル化レプチン組成物および関連する方法 |
US7345019B1 (en) | 1999-04-13 | 2008-03-18 | The Kenneth S. Warren Institute, Inc. | Modulation of excitable tissue function by peripherally administered erythropoietin |
US7410941B1 (en) | 1999-04-13 | 2008-08-12 | The Kenneth S. Warren Institute, Inc. | Methods for treatment of neurodegenerative conditions by peripherally administered erythropoietin |
US8236561B2 (en) | 1999-04-15 | 2012-08-07 | Crucell Holland B.V. | Efficient production of IgA in recombinant mammalian cells |
US6855544B1 (en) | 1999-04-15 | 2005-02-15 | Crucell Holland B.V. | Recombinant protein production in a human cell |
WO2003048348A2 (en) | 2001-12-07 | 2003-06-12 | Crucell Holland B.V. | Production of viruses, viral isolates and vaccines |
US7297680B2 (en) | 1999-04-15 | 2007-11-20 | Crucell Holland B.V. | Compositions of erythropoietin isoforms comprising Lewis-X structures and high sialic acid content |
US7604960B2 (en) | 1999-04-15 | 2009-10-20 | Crucell Holland B.V. | Transient protein expression methods |
US6555343B1 (en) | 1999-05-07 | 2003-04-29 | Genentech Inc. | Chimpanzee erythropoietin (CHEPO) polypeptides and nucleic acids encoding the same |
WO2000068376A1 (en) * | 1999-05-07 | 2000-11-16 | Genentech, Inc. | Novel chimpanzee erythropoietin (chepo) polypeptides and nucleic acids encoding the same |
US6831060B2 (en) | 1999-05-07 | 2004-12-14 | Genentech, Inc. | Chimpanzee erythropoietin (CHEPO) polypeptides and nucleic acids encoding the same |
CZ299516B6 (cs) * | 1999-07-02 | 2008-08-20 | F. Hoffmann-La Roche Ag | Konjugát erythropoetinového glykoproteinu, zpusobjeho výroby a použití a farmaceutická kompozice sjeho obsahem |
PE20010288A1 (es) * | 1999-07-02 | 2001-03-07 | Hoffmann La Roche | Derivados de eritropoyetina |
SK782002A3 (en) | 1999-07-21 | 2003-08-05 | Lexigen Pharm Corp | FC fusion proteins for enhancing the immunogenicity of protein and peptide antigens |
JP2003514552A (ja) * | 1999-11-12 | 2003-04-22 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフトング | 改善された性質を有するエリトロポエチンの形態 |
US7521220B2 (en) | 1999-11-26 | 2009-04-21 | Crucell Holland B.V. | Production of vaccines |
US7192759B1 (en) | 1999-11-26 | 2007-03-20 | Crucell Holland B.V. | Production of vaccines |
US7527961B2 (en) | 1999-11-26 | 2009-05-05 | Crucell Holland B.V. | Production of vaccines |
CA2399832C (en) | 2000-02-11 | 2011-09-20 | Stephen D. Gillies | Enhancing the circulating half-life of antibody-based fusion proteins |
US6586398B1 (en) * | 2000-04-07 | 2003-07-01 | Amgen, Inc. | Chemically modified novel erythropoietin stimulating protein compositions and methods |
JP5022551B2 (ja) * | 2000-04-21 | 2012-09-12 | アムジエン・インコーポレーテツド | 貧血の予防及び治療用の方法及び組成物 |
EP1525889A1 (en) | 2000-05-15 | 2005-04-27 | F. Hoffmann-La Roche Ag | Liquid pharmaceutical composition containing an erythropoietin derivative |
US7259146B2 (en) | 2000-05-26 | 2007-08-21 | Ortho-Mcneil Pharmaceutical, Inc. | Neuroprotective peptides |
AU2001276737A1 (en) | 2000-08-04 | 2002-02-18 | Chugai Seiyaku Kabushiki Kaisha | Protein injection preparations |
JP5485489B2 (ja) | 2000-08-11 | 2014-05-07 | 中外製薬株式会社 | 抗体含有安定化製剤 |
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NZ210501A (en) * | 1983-12-13 | 1991-08-27 | Kirin Amgen Inc | Erythropoietin produced by procaryotic or eucaryotic expression of an exogenous dna sequence |
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KR100263845B1 (ko) * | 1989-10-13 | 2000-08-16 | 스튜어트 엘.왓트 | 에리트로포이에틴 동형체와 그의 제조방법 및 그를 포함하는제약학적 조성물 |
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