NO178234C - Fremgangsmåte for fremstilling av et kimærisk antistoffmolekyl - Google Patents

Fremgangsmåte for fremstilling av et kimærisk antistoffmolekyl

Info

Publication number
NO178234C
NO178234C NO884771A NO884771A NO178234C NO 178234 C NO178234 C NO 178234C NO 884771 A NO884771 A NO 884771A NO 884771 A NO884771 A NO 884771A NO 178234 C NO178234 C NO 178234C
Authority
NO
Norway
Prior art keywords
preparation
antibody molecule
chimeric antibody
chimeric
molecule
Prior art date
Application number
NO884771A
Other languages
English (en)
Norwegian (no)
Other versions
NO178234B (no
NO884771D0 (no
NO884771L (no
Inventor
Kim R Folger Bruce
Jr Henry Perry Fell
Original Assignee
Oncogen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oncogen filed Critical Oncogen
Publication of NO884771D0 publication Critical patent/NO884771D0/no
Publication of NO884771L publication Critical patent/NO884771L/no
Priority to NO952051A priority Critical patent/NO952051L/no
Publication of NO178234B publication Critical patent/NO178234B/no
Publication of NO178234C publication Critical patent/NO178234C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/64—General methods for preparing the vector, for introducing it into the cell or for selecting the vector-containing host
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/46—Hybrid immunoglobulins
    • C07K16/461—Igs containing Ig-regions, -domains or -residues form different species
    • C07K16/462—Igs containing a variable region (Fv) from one specie and a constant region (Fc) from another
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C07K2317/732—Antibody-dependent cellular cytotoxicity [ADCC]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Plant Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
NO884771A 1987-10-27 1988-10-26 Fremgangsmåte for fremstilling av et kimærisk antistoffmolekyl NO178234C (no)

Priority Applications (1)

Application Number Priority Date Filing Date Title
NO952051A NO952051L (no) 1987-10-27 1995-05-23 Fremgangsmåte for fremstilling av et kimærisk antistoffmolekyl

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11380087A 1987-10-27 1987-10-27
US07/243,873 US5204244A (en) 1987-10-27 1988-09-14 Production of chimeric antibodies by homologous recombination

Publications (4)

Publication Number Publication Date
NO884771D0 NO884771D0 (no) 1988-10-26
NO884771L NO884771L (no) 1989-04-28
NO178234B NO178234B (no) 1995-11-06
NO178234C true NO178234C (no) 1996-02-14

Family

ID=26811495

Family Applications (1)

Application Number Title Priority Date Filing Date
NO884771A NO178234C (no) 1987-10-27 1988-10-26 Fremgangsmåte for fremstilling av et kimærisk antistoffmolekyl

Country Status (17)

Country Link
US (1) US5204244A (xx)
EP (1) EP0315062B1 (xx)
JP (1) JP2624314B2 (xx)
CN (1) CN1033290A (xx)
AU (1) AU607013B2 (xx)
CA (1) CA1334177C (xx)
CY (1) CY1778A (xx)
DE (1) DE3887085T2 (xx)
DK (1) DK174339B1 (xx)
ES (1) ES2061598T3 (xx)
FI (1) FI97303C (xx)
HK (1) HK63094A (xx)
IE (1) IE61733B1 (xx)
IL (1) IL88149A (xx)
NO (1) NO178234C (xx)
NZ (1) NZ226695A (xx)
PT (1) PT88858B (xx)

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CA1334177C (en) 1995-01-31
NO178234B (no) 1995-11-06
IE883244L (en) 1989-04-27
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CN1033290A (zh) 1989-06-07
FI884907A0 (fi) 1988-10-24
DE3887085T2 (de) 1994-05-19
CY1778A (en) 1995-10-20
IL88149A (en) 1993-06-10
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DK594588A (da) 1989-04-28
AU607013B2 (en) 1991-02-21
FI97303C (fi) 1996-11-25
ES2061598T3 (es) 1994-12-16
IL88149A0 (en) 1989-06-30
FI884907A (fi) 1989-04-28
NO884771L (no) 1989-04-28
EP0315062A2 (en) 1989-05-10
EP0315062A3 (en) 1990-03-28
DK174339B1 (da) 2002-12-16
JPH02477A (ja) 1990-01-05
EP0315062B1 (en) 1994-01-12
FI97303B (fi) 1996-08-15
JP2624314B2 (ja) 1997-06-25
PT88858B (pt) 1993-01-29
HK63094A (en) 1994-07-01
DE3887085D1 (de) 1994-02-24
DK594588D0 (da) 1988-10-26
US5204244A (en) 1993-04-20
AU2444688A (en) 1989-04-27

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