MX9602656A - Dispositivo transdermico que contiene pirrolidona polivinilica como mejorador de solubilidad. - Google Patents

Dispositivo transdermico que contiene pirrolidona polivinilica como mejorador de solubilidad.

Info

Publication number
MX9602656A
MX9602656A MX9602656A MX9602656A MX9602656A MX 9602656 A MX9602656 A MX 9602656A MX 9602656 A MX9602656 A MX 9602656A MX 9602656 A MX9602656 A MX 9602656A MX 9602656 A MX9602656 A MX 9602656A
Authority
MX
Mexico
Prior art keywords
pressure
sensitive adhesive
adhesive composition
drug
device containing
Prior art date
Application number
MX9602656A
Other languages
English (en)
Inventor
Jesus Miranda
Steven Sablotsky
Original Assignee
Noven Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22653013&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX9602656(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Noven Pharma filed Critical Noven Pharma
Publication of MX9602656A publication Critical patent/MX9602656A/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00Bandages or dressings; Absorbent pads
    • A61F13/02Adhesive bandages or dressings
    • A61F13/0276Apparatus or processes for manufacturing adhesive dressings or bandages
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061Polyacrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7069Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. polysiloxane, polyesters, polyurethane, polyethylene oxide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/18Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing inorganic materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42Use of materials characterised by their function or physical properties
    • A61L15/58Adhesives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42Use of materials characterised by their function or physical properties
    • A61L15/58Adhesives
    • A61L15/585Mixtures of macromolecular compounds
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B26HAND CUTTING TOOLS; CUTTING; SEVERING
    • B26FPERFORATING; PUNCHING; CUTTING-OUT; STAMPING-OUT; SEVERING BY MEANS OTHER THAN CUTTING
    • B26F1/00Perforating; Punching; Cutting-out; Stamping-out; Apparatus therefor
    • B26F1/38Cutting-out; Stamping-out
    • B26F1/384Cutting-out; Stamping-out using rotating drums

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • Materials Engineering (AREA)
  • Inorganic Chemistry (AREA)
  • Manufacturing & Machinery (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)

Abstract

La presente invencion se refiere en general a sistemas de aplicacion transdérmica de fármacos, y más particularmente, a una composicion de aplicacion transdérmica de fármacos en donde se utiliza una mezcla de polímeros para afectar la solubilidad del fármaco y la velocidad de aplicacion del fármaco a partir de la composicion. De una manera más específica, una pluralidad de polímeros, de preferencia polivinílica ("PVP) soluble, la cual puede incrementar la máxima concentracion disponible del fármaco en la mezcla, permitiendo de esta manera una reduccion mayor en el tamaño del sistema necesario par alcanzar niveles terapéuticos, mientras que se mantienen las propiedades de aplicacion y adhesivas deseadas.
MX9602656A 1994-01-07 1996-07-05 Dispositivo transdermico que contiene pirrolidona polivinilica como mejorador de solubilidad. MX9602656A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/178,558 US5656286A (en) 1988-03-04 1994-01-07 Solubility parameter based drug delivery system and method for altering drug saturation concentration

Publications (1)

Publication Number Publication Date
MX9602656A true MX9602656A (es) 1998-06-30

Family

ID=22653013

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9602656A MX9602656A (es) 1994-01-07 1996-07-05 Dispositivo transdermico que contiene pirrolidona polivinilica como mejorador de solubilidad.

Country Status (22)

Country Link
US (3) US5656286A (es)
EP (2) EP1329225A3 (es)
JP (1) JP4339398B2 (es)
KR (1) KR100363052B1 (es)
CN (1) CN1121854C (es)
AT (1) ATE235898T1 (es)
BR (1) BR9506470B8 (es)
CA (1) CA2180530C (es)
DE (1) DE69530177T2 (es)
DK (1) DK0737066T3 (es)
ES (1) ES2196055T3 (es)
FI (1) FI121527B (es)
HU (1) HU227814B1 (es)
IL (1) IL112269A (es)
MX (1) MX9602656A (es)
NO (1) NO319377B1 (es)
NZ (1) NZ278769A (es)
PT (1) PT737066E (es)
SG (1) SG49331A1 (es)
TW (1) TW464511B (es)
WO (1) WO1995018603A1 (es)
ZA (1) ZA95108B (es)

Families Citing this family (498)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5252334A (en) * 1989-09-08 1993-10-12 Cygnus Therapeutic Systems Solid matrix system for transdermal drug delivery
US6492349B1 (en) * 1993-03-31 2002-12-10 Nutramax Laboratories, Inc. Aminosugar and glycosaminoglycan composition for the treatment and repair of connective tissue
US5919478A (en) * 1993-06-25 1999-07-06 Alza Corporation Incorporating poly-N-vinyl amide in a transdermal system
DE4442999A1 (de) 1994-12-02 1996-06-05 Hexal Pharma Gmbh Pharmazeutische Zusammensetzung mit einem aktiven Loratidin-Metaboliten
DE4443888A1 (de) * 1994-12-09 1996-06-13 Bayer Ag Dermal applizierbare Formulierungen von Parasitiziden
IL116539A (en) * 1995-01-06 2002-02-10 Noven Pharma Preparations given through the skin of unstable anti-acid drugs
US6024974A (en) * 1995-01-06 2000-02-15 Noven Pharmaceuticals, Inc. Composition and methods for transdermal delivery of acid labile drugs
DE19503338C2 (de) * 1995-02-02 1998-07-30 Lohmann Therapie Syst Lts Arzneiform zur Abgabe von Kollagenase an Wunden und Verfahren zu ihrer Herstellung und ihre Verwendung
DE19512181C2 (de) * 1995-03-31 2003-11-06 Hexal Pharma Gmbh Transdermales System mit Ramipril und/oder Trandolapril als ACE-Hemmer
AUPN262595A0 (en) * 1995-04-24 1995-05-18 Novapharm Research (Australia) Pty Limited Biocidal surface films
US6730294B1 (en) 1995-04-24 2004-05-04 Novapharm Research (Australia) Pty Limited Method of forming a water soluble biocidal film on a solid surface
HU228434B1 (en) 1995-06-07 2013-03-28 Ortho Mcneil Pharm Inc Transdermal medicament for administering 17-deacetyl norgestimate alone or in combination with an estrogen
AU718096C (en) * 1995-06-07 2001-11-22 Noven Pharmaceuticals, Inc. Transdermal compositions containing low molecular weight drugs which are liquid at room temperatures
US6316022B1 (en) * 1995-06-07 2001-11-13 Noven Pharmaceuticals, Inc. Transdermal compositions containing low molecular weight drugs which are liquid at room temperatures
US5780050A (en) * 1995-07-20 1998-07-14 Theratech, Inc. Drug delivery compositions for improved stability of steroids
FR2739031B1 (fr) * 1995-09-27 1997-11-21 Lhd Lab Hygiene Dietetique Systeme matriciel transdermique d'administration d'un oestrogene et/ou d'un progestatif a base de copolymere styrene-isoprene-styrene, procede de preparation et utilisation en therapeutique
US5702720A (en) * 1995-12-22 1997-12-30 Minnesota Mining And Manufacturing Company Transdermal device for the delivery of flurbiprofen
ATE222759T1 (de) * 1996-02-07 2002-09-15 Lead Chem Co Ltd Tranilast enthaltendes externum und verfahren zu dessen herstellung
US5725876A (en) * 1996-05-17 1998-03-10 Noven Pharmaceuticals Inc., Compositions and methods for using low-swell clays in nicotine containing dermal compositions
US6623752B1 (en) * 1996-07-02 2003-09-23 Hexal Ag Patch for transdermal application for pergolid
DE19635883A1 (de) * 1996-09-04 1998-03-05 Lohmann Therapie Syst Lts Transdermales therapeutisches System mit einer Östriol enthaltenden Wirkstoffkombination
WO1999011208A1 (en) * 1997-08-28 1999-03-11 Williams C Donald Method and composition for transdermal administration of pharmacologic agents
US6479074B2 (en) 1996-10-24 2002-11-12 Pharmaceutical Applications Associates Llc Methods and transdermal compositions for pain relief
US6290986B1 (en) 1996-10-24 2001-09-18 Pharmaceutical Applications Associates, Llc Method and composition for transdermal administration of pharmacologic agents
US6572880B2 (en) 1996-10-24 2003-06-03 Pharmaceutical Applications Associates Llc Methods and transdermal compositions for pain relief
DE19646392A1 (de) 1996-11-11 1998-05-14 Lohmann Therapie Syst Lts Zubereitung zur Anwendung in der Mundhöhle mit einer an der Schleimhaut haftklebenden, Pharmazeutika oder Kosmetika zur dosierten Abgabe enthaltenden Schicht
US20060002949A1 (en) 1996-11-14 2006-01-05 Army Govt. Of The Usa, As Rep. By Secretary Of The Office Of The Command Judge Advocate, Hq Usamrmc. Transcutaneous immunization without heterologous adjuvant
EP1004304A4 (en) * 1996-12-24 2002-10-16 Sumitomo Pharma COMPOSITION WITH ACORBIC ACID
US5968547A (en) * 1997-02-24 1999-10-19 Euro-Celtique, S.A. Method of providing sustained analgesia with buprenorphine
DK48997A (da) 1997-04-30 1999-01-05 Coloplast As Klæbemiddel samt anvendelse af dette middel
IT1292129B1 (it) * 1997-06-11 1999-01-25 Sunnimex Ltd Medicamento utile per ridurre la massa grassa ed aumentare la massa magra nella donna in menopausa ed in entrambi i sessi nella
EP0998274B1 (en) 1997-06-23 2006-01-18 Cellegy Pharmaceuticals, Inc Microdose therapy of vascular conditions by no donors
US7150881B2 (en) * 1997-06-26 2006-12-19 Mylan Technologies, Inc. Adhesive mixture for transdermal delivery of highly plasticizing drugs
DE69805305T2 (de) * 1997-08-21 2002-12-05 P.N. Gerolymatos S.A., Kruoneri Verwendung von phanquinon zur behandlung von alzheimer's krankheit
JP2001515026A (ja) * 1997-08-21 2001-09-18 ジョンソン・アンド・ジョンソン・コンシューマー・カンパニーズ・インコーポレイテッド 加齢または日光により損傷した皮膚および/または皮膚萎縮の処置のための17−α−エストラジオールの使用
US6488940B2 (en) 1997-08-21 2002-12-03 Johnson & Johnson Consumer Companies, Inc. Use of 17-α-estradiol for the treatment of aged or sundamaged skin and/or skin atrophy
DE19738643C2 (de) * 1997-09-04 2001-10-04 Lohmann Therapie Syst Lts Transdermales therapeutisches System mit dem Wirkstoff Scopolaminbase und Verfahren zu seiner Herstellung
US6767902B2 (en) * 1997-09-17 2004-07-27 The Population Council, Inc. Androgen as a male contraceptive and non-contraceptive androgen replacement
GB9720470D0 (en) 1997-09-25 1997-11-26 Ethical Pharmaceuticals South Inhibition of crystallization in transdermal devices
US20040018241A1 (en) * 1997-09-26 2004-01-29 Noven Pharmaceuticals, Inc. Bioadhesive compositions and methods for topical administration of active agents
DE69833000T2 (de) * 1997-09-26 2006-09-07 Noven Pharmaceuticals, Inc., Miami Bio-klebemittelzusammensetzungen
JP3460538B2 (ja) * 1997-10-08 2003-10-27 救急薬品工業株式会社 速溶性フィルム製剤
WO1999026571A1 (en) * 1997-11-25 1999-06-03 Theratech, Inc. Transdermal delivery devices containing polydiorganosiloxane polymers to regulate adhesive properties
JP3930984B2 (ja) * 1997-12-12 2007-06-13 日東電工株式会社 経皮吸収型製剤
US20020102291A1 (en) * 1997-12-15 2002-08-01 Noven Pharmaceuticals, Inc. Compositions and method for treatment of attention deficit disorder and attention deficit/hyperactivity disorder with methylphenidate
US6210705B1 (en) 1997-12-15 2001-04-03 Noven Pharmaceuticals, Nc. Compositions and methods for treatment of attention deficit disorder and attention deficit/hyperactivity disorder with methylphenidate
US6146656A (en) * 1998-01-22 2000-11-14 Nitto Denko Corporation Percutaneous absorption preparation
EP1058546A4 (en) * 1998-03-06 2004-07-28 Univ Texas COMPILATIONS AND METHODS FOR THE TREATMENT OF MACULA DISEASES
DE19814084B4 (de) * 1998-03-30 2005-12-22 Lts Lohmann Therapie-Systeme Ag D2-Agonist enthaltendes transdermales therapeutisches System zur Behandlung des Parkinson-Syndroms und Verfahren zu seiner Herstellung
DE19814257A1 (de) * 1998-03-31 1999-10-07 Asta Medica Ag Brauseformulierungen
US6372254B1 (en) * 1998-04-02 2002-04-16 Impax Pharmaceuticals Inc. Press coated, pulsatile drug delivery system suitable for oral administration
ATE219693T1 (de) 1998-04-27 2002-07-15 Surmodics Inc Bioaktive wirkstoffe freisetzende beschichtungen
US6455064B1 (en) 1998-04-30 2002-09-24 Closure Medical Corporation Method of applying an adhesive composition over a bioactive polymerization initiator or accelerator
US20050196431A1 (en) * 1998-04-30 2005-09-08 Upvan Narang Adhesive applicator tip with a polymerization initiator, polymerization rate modifier, and/or bioactive material
US6197347B1 (en) 1998-06-29 2001-03-06 Andrx Pharmaceuticals, Inc. Oral dosage for the controlled release of analgesic
IT1299566B1 (it) * 1998-07-17 2000-03-16 Ifi Istituto Farmacoterapico I Cerotto transdermico e composizioni farmaceutiche comprendenti r (-)- norapropilapomorfina cloridrato e/o s (+) - norapropilapomorfina
US6699497B1 (en) * 1998-07-24 2004-03-02 Alza Corporation Formulations for the transdermal administration of fenoldopam
JP2002521324A (ja) * 1998-07-24 2002-07-16 アルザ コーポレイション フェノルドパムの経皮投与のための配合物
JP3943724B2 (ja) * 1998-07-31 2007-07-11 東光薬品工業株式会社 フェンタニル含有経皮投与マトリックス型貼付剤
US20040170675A1 (en) * 1998-08-03 2004-09-02 Easterling W. Jerry Noninvasive method for treating cellulite through transdermal delivery of calcium channel blocker agents and medicament for use in such method
DK1105096T3 (da) * 1998-08-19 2004-03-08 Skyepharma Canada Inc Injicerbare vandige propofoldispersioner
NZ509618A (en) * 1998-08-20 2003-09-26 3M Innovative Properties Co A patch-in-a-bottle that provides a fluid composition, which is applied to a surface and subsequently dries to form a covering, such as a patch
PT1117390E (pt) * 1998-10-02 2005-01-31 3M Innovative Properties Co Sistemas de distribuicao de farmacos originarios da mucosa e aplicacoes em animais
US7001609B1 (en) 1998-10-02 2006-02-21 Regents Of The University Of Minnesota Mucosal originated drug delivery systems and animal applications
US6475514B1 (en) 1998-12-03 2002-11-05 Andrew Blitzer Athletic patch
NZ512788A (en) * 1998-12-07 2003-07-25 Elan Corp Plc Transdermal patch for delivering volatile liquid drugs
US20030170195A1 (en) * 2000-01-10 2003-09-11 Noven Pharmaceuticals, Inc. Compositions and methods for drug delivery
PT1061900E (pt) * 1999-01-14 2005-04-29 Noven Pharma Composicoes e metodos para libertacao de uma droga
US6337086B1 (en) 1999-02-06 2002-01-08 Dow Corning Corporation Pressure sensitive adhesive compositions for transdermal drug delivery devices
DE19906152B4 (de) 1999-02-10 2005-02-10 Jenapharm Gmbh & Co. Kg Wirkstoffhaltige Laminate für Transdermalsysteme
US6455055B1 (en) 1999-02-12 2002-09-24 The Procter & Gamble Company Cosmetic compositions
US6309657B2 (en) 1999-02-12 2001-10-30 The Procter & Gamble Company Cosmetic compositions
US6224888B1 (en) * 1999-02-12 2001-05-01 The Procter & Gamble Company Cosmetic compositions
US6325993B1 (en) * 1999-03-03 2001-12-04 Nitto Denko Corporation Oral adhesive sheet and oral adhesive preparation
US7063859B1 (en) 1999-04-28 2006-06-20 Noven Pharmaceuticals, Inc. Barrier film lined backing layer composition and method for topical administration of active agents
WO2000074661A2 (en) 1999-06-05 2000-12-14 Noven Pharmaceuticals, Inc. Solubility enhancement of drugs in transdermal drug delivery systems and methods of use
DE19929197A1 (de) * 1999-06-25 2000-12-28 Novosis Pharma Ag Transdermalsysteme zur Abgabe von 5-HT3-Rezeptor-Antagonisten und ihre Verwendung zur antiemitischen Behandlung
PL197492B1 (pl) * 1999-07-02 2008-04-30 Lohmann Therapie Syst Lts Transdermalny system terapeutyczny zawierający warstwę polimerową z zawartymi w niej mikrozbiornikami i sposób wytwarzania błon
US6780880B1 (en) * 1999-08-26 2004-08-24 Robert R. Whittle FT-Raman spectroscopic measurement
US6312723B1 (en) 1999-08-26 2001-11-06 Robert R. Whittle Pharmaceutical unit dosage form
US6262085B1 (en) 1999-08-26 2001-07-17 Robert R. Whittle Alkoxy substituted Benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same
US6369087B1 (en) 1999-08-26 2002-04-09 Robert R. Whittle Alkoxy substituted benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same
US6262086B1 (en) 1999-08-26 2001-07-17 Robert R. Whittle Pharmaceutical unit dosage form
US6326384B1 (en) 1999-08-26 2001-12-04 Robert R. Whittle Dry blend pharmaceutical unit dosage form
US6316020B1 (en) 1999-08-26 2001-11-13 Robert R. Whittle Pharmaceutical formulations
US6268385B1 (en) 1999-08-26 2001-07-31 Robert R. Whittle Dry blend pharmaceutical formulations
US6312712B1 (en) 1999-08-26 2001-11-06 Robert R. Whittle Method of improving bioavailability
EP1221315A4 (en) * 1999-10-13 2007-12-12 Senju Pharma Co ADHESIVE OPHTHALMIC PREPARATIONS FOR PERCUTANEOUS SPREADING
CA2389865A1 (en) * 1999-11-04 2001-05-10 Xel Herbaceuticals Transdermal administration of huperzine
AU1780101A (en) * 1999-11-19 2001-05-30 Xel Herbaceuticals Transdermal delivery system for alkaloids of aconitum species
US6896898B1 (en) 1999-11-19 2005-05-24 Xel Herbaceuticals, Inc. Transdermal delivery system for alkaloids of aconitum species
US20050042271A1 (en) * 1999-11-19 2005-02-24 Xel Herbaceuticals, Inc . Transdermal delivery system for alkaloids of aconitum species
US6974588B1 (en) * 1999-12-07 2005-12-13 Elan Pharma International Limited Transdermal patch for delivering volatile liquid drugs
US7732404B2 (en) * 1999-12-30 2010-06-08 Dexcel Ltd Pro-nanodispersion for the delivery of cyclosporin
US20020004065A1 (en) 2000-01-20 2002-01-10 David Kanios Compositions and methods to effect the release profile in the transdermal administration of active agents
US6730691B1 (en) 2000-02-10 2004-05-04 Miles A. Galin Uses of alpha adrenergic blocking agents
US6905016B2 (en) * 2000-03-14 2005-06-14 Noven Pharmaceuticals, Inc. Packaging system for transdermal drug delivery systems
US9522217B2 (en) 2000-03-15 2016-12-20 Orbusneich Medical, Inc. Medical device with coating for capturing genetically-altered cells and methods for using same
US20070141107A1 (en) * 2000-03-15 2007-06-21 Orbusneich Medical, Inc. Progenitor Endothelial Cell Capturing with a Drug Eluting Implantable Medical Device
US8088060B2 (en) 2000-03-15 2012-01-03 Orbusneich Medical, Inc. Progenitor endothelial cell capturing with a drug eluting implantable medical device
DE10012908B4 (de) * 2000-03-16 2005-03-17 Lts Lohmann Therapie-Systeme Ag Stabilisierte übersättigte transdermale therapeutische Matrixsysteme und Verfahren zu ihrer Herstellung
FR2806625B1 (fr) * 2000-03-23 2002-08-30 Pf Medicament Dispositif matriciel pour l'administration transdermique de rilmenidine et son procede de preparation
JP2003528914A (ja) * 2000-04-03 2003-09-30 エフ.ホフマン−ラ ロシュ アーゲー カルベジロールの濃縮溶液
US7179483B2 (en) * 2000-04-26 2007-02-20 Watson Pharmaceuticals, Inc. Compositions and methods for transdermal oxybutynin therapy
KR100452972B1 (ko) * 2000-05-16 2004-10-14 주식회사 삼양사 경피투여용 하이드로젤 조성물
DE10025971B4 (de) * 2000-05-25 2004-09-02 Lts Lohmann Therapie-Systeme Ag Transdermales therapeutisches System in Plasterform mit verminderter Tendenz zur Wirkstoffkristallisation und seine Verwendung
US6579544B1 (en) 2000-05-31 2003-06-17 Nutriex, L.L.C. Method for supplementing the diet
USRE44145E1 (en) 2000-07-07 2013-04-09 A.V. Topchiev Institute Of Petrochemical Synthesis Preparation of hydrophilic pressure sensitive adhesives having optimized adhesive properties
US8980290B2 (en) 2000-08-03 2015-03-17 Antares Pharma Ipl Ag Transdermal compositions for anticholinergic agents
JP4837877B2 (ja) * 2000-08-22 2011-12-14 日油株式会社 コンタクトレンズ用装着液
DE10041478A1 (de) * 2000-08-24 2002-03-14 Sanol Arznei Schwarz Gmbh Neue pharmazeutische Zusammensetzung
DE10066158B4 (de) * 2000-08-24 2007-08-09 Neurobiotec Gmbh Verwendung eines transdermalen therapeutischen Systems zur Behandlung des Restless-Legs-Syndroms
DE10053397A1 (de) * 2000-10-20 2002-05-02 Schering Ag Verwendung eines dopaminergen Wirkstoffes zur Behandlung von dopaminerg behandelbaren Erkrankungen
US20070243240A9 (en) * 2000-08-24 2007-10-18 Fred Windt-Hanke Transdermal therapeutic system
US6503894B1 (en) 2000-08-30 2003-01-07 Unimed Pharmaceuticals, Inc. Pharmaceutical composition and method for treating hypogonadism
EP1318843B1 (en) * 2000-09-19 2013-04-17 Henkel AG & Co. KGaA Acryl adhesive useful in transdermal drug delivery systems
US20020119187A1 (en) 2000-09-29 2002-08-29 Cantor Adam S. Composition for the transdermal delivery of fentanyl
EP1334724A4 (en) * 2000-10-16 2007-05-02 Hisamitsu Pharmaceutical Co COMPOSITIONS FOR TOPICAL PREPARATIONS
HUP0303719A2 (hu) * 2000-10-16 2004-03-01 Neopharm, Inc. Mitoxantron hatóanyag-tartalmú liposzómás gyógyszerkészítmények és eljárás az előállításukra
US20020198215A1 (en) * 2000-10-23 2002-12-26 Lino Tavares Terazosin transdermal device and methods
GB0026137D0 (en) * 2000-10-25 2000-12-13 Euro Celtique Sa Transdermal dosage form
US20040028724A1 (en) * 2000-11-07 2004-02-12 Takaaki Terahara Pharmaceutical preparation of percutaneous absorption type
KR20020037616A (ko) * 2000-11-15 2002-05-22 서경배 케토롤락의 경피흡수제제
WO2002045701A2 (en) * 2000-12-05 2002-06-13 Noven Pharmaceuticals, Inc. Crystallization inhibition of drugs in transdermal drug delivery systems
DE10064453A1 (de) * 2000-12-16 2002-07-04 Schering Ag Verwendung eines dopaminergen Wirkstoffes zur Behandlung von dopaminerg behandelbaren Erkrankungen
EP1216699A1 (de) * 2000-12-21 2002-06-26 Schering Aktiengesellschaft Transdermalsystem enthaltend ein hochpotentes Gestagen
US6479076B2 (en) * 2001-01-12 2002-11-12 Izhak Blank Nicotine delivery compositions
CA2438641A1 (en) * 2001-02-15 2002-08-22 King Pharmaceuticals, Inc. Stabilized pharmaceutical and thyroid hormone compositions and method of preparation
US20030032675A1 (en) * 2001-02-15 2003-02-13 Franz G. Andrew Manufacture of thyroid hormone tablets having consistent active moiety amounts
US6555581B1 (en) 2001-02-15 2003-04-29 Jones Pharma, Inc. Levothyroxine compositions and methods
US20030224047A1 (en) * 2001-02-15 2003-12-04 Franz G. Andrew Levothyroxine compositions and methods
EP1366762B1 (en) * 2001-03-07 2015-12-30 Hisamitsu Pharmaceutical Co., Inc. Adhesive patch
DE20220982U1 (de) 2001-03-16 2004-11-25 Alza Corp., Mountain View Transdermal-Pflaster zum Verabreichen von Fentanyl
CA2440884C (en) * 2001-03-16 2012-05-22 Alza Corporation Transdermal patch for administering fentanyl
US20050208117A1 (en) * 2001-03-16 2005-09-22 Venkatraman Subramanian S Transdermal administration of fentanyl and analogs thereof
US6509007B2 (en) * 2001-03-19 2003-01-21 The Procter & Gamble Company Oral care kits and compositions
US6500406B1 (en) * 2001-03-19 2002-12-31 The Procter & Gamble Company Denture care compositions and kits
US6514484B2 (en) * 2001-03-19 2003-02-04 The Procter & Gamble Company Systems for delivering a cosmetic and/or therapeutic active to oral surfaces using an integral carrier
US6491896B1 (en) * 2001-03-19 2002-12-10 The Proctor & Gamble Company Polybutene containing denture cleanser compositions
DE10118282A1 (de) * 2001-04-12 2002-12-05 Lohmann Therapie Syst Lts Haftkleber auf Basis von Ethylen-Vinylacetat-Copolymeren und Klebharzen, für medizinische Verwendungszwecke
US8728445B2 (en) 2001-05-01 2014-05-20 A.V. Topchiev Institute Of Petrochemical Synthesis, Russian Academy Of Sciences Hydrogel Compositions
US8541021B2 (en) 2001-05-01 2013-09-24 A.V. Topchiev Institute Of Petrochemical Synthesis Hydrogel compositions demonstrating phase separation on contact with aqueous media
US20050113510A1 (en) 2001-05-01 2005-05-26 Feldstein Mikhail M. Method of preparing polymeric adhesive compositions utilizing the mechanism of interaction between the polymer components
US8206738B2 (en) 2001-05-01 2012-06-26 Corium International, Inc. Hydrogel compositions with an erodible backing member
DE60239528D1 (de) * 2001-05-01 2011-05-05 Corium International Redwood City Zweiphasige, wasserabsorbierende bioadhäsive zusammenstezung
US8840918B2 (en) 2001-05-01 2014-09-23 A. V. Topchiev Institute of Petrochemical Synthesis, Russian Academy of Sciences Hydrogel compositions for tooth whitening
US20050215727A1 (en) * 2001-05-01 2005-09-29 Corium Water-absorbent adhesive compositions and associated methods of manufacture and use
CA2446060A1 (en) * 2001-05-07 2002-11-14 Corium International Compositions and delivery systems for administration of a local anesthetic agent
PT1256339E (pt) * 2001-05-08 2004-02-27 Lohmann Therapie Syst Lts Sistema terapeutico transdermico para doenca de parkinson que induz niveis plasmaticos altos de rotigotina
US20030026830A1 (en) * 2001-05-08 2003-02-06 Thomas Lauterback Transdermal therapeutic system for parkinson's disease inducing high plasma levels of rotigotine
US20030027793A1 (en) * 2001-05-08 2003-02-06 Thomas Lauterback Transdermal treatment of parkinson's disease
JP4865958B2 (ja) * 2001-05-23 2012-02-01 株式会社トクホン 鎮痛抗炎症局所作用型の貼付剤
TWI277418B (en) 2001-06-18 2007-04-01 Noven Pharma Enhanced drug delivery in transdermal systems
US7244703B2 (en) * 2001-06-22 2007-07-17 Bentley Pharmaceuticals, Inc. Pharmaceutical compositions and methods for peptide treatment
DE10141651B4 (de) * 2001-08-24 2007-02-15 Lts Lohmann Therapie-Systeme Ag Transdermales Therapeutisches System (TTS) mit dem Wirkstoff Fentanyl und Verfahren zu seiner Herstellung
DE10137082A1 (de) * 2001-07-28 2003-02-13 Hexal Ag Matrixkontrolliertes transdermales therapeutisches System zur Anwendung von Pramiprexol und Ropinirol
DE10137162A1 (de) * 2001-07-30 2003-02-20 Hexal Ag Matrixkontrolliertes transdermales therapeutisches System zur Anwendung von Pramiprexol und Ropinirol
US20030198667A1 (en) * 2001-08-10 2003-10-23 Franz Andrew G. Methods of producing dispersible pharmaceutical compositions
US20030190349A1 (en) * 2001-08-10 2003-10-09 Franz G. Andrew Methods of stabilizing pharmaceutical compositions
US20030198671A1 (en) * 2001-08-10 2003-10-23 Franz G. Andrew Levothyroxine compositions having unique plasma AUC properties
US20030180353A1 (en) * 2001-08-10 2003-09-25 Franz G. Andrew Stabilized pharmaceutical compositions
US20030198672A1 (en) * 2001-08-14 2003-10-23 Franz G. Andrew Levothyroxine compositions having unique triidothyronine plasma AUC properties
US20030195253A1 (en) * 2001-08-14 2003-10-16 Franz G. Andrew Unadsorbed levothyroxine pharmaceutical compositions, methods of making and methods of administration
US20030203967A1 (en) * 2001-08-14 2003-10-30 Franz G. Andrew Levothyroxine compositions having unique Tmax properties
US20030199587A1 (en) * 2001-08-14 2003-10-23 Franz G. Andrew Levothyroxine compositions having unique Cmax properties
US20030199586A1 (en) * 2001-08-14 2003-10-23 Franz G. Andrew Unique levothyroxine aqueous materials
US7101569B2 (en) 2001-08-14 2006-09-05 Franz G Andrew Methods of administering levothyroxine pharmaceutical compositions
DE10141650C1 (de) 2001-08-24 2002-11-28 Lohmann Therapie Syst Lts Transdermales Therapeutisches System mit Fentanyl bzw. verwandten Substanzen
WO2003022270A1 (en) * 2001-09-13 2003-03-20 Noven Pharmaceuticals, Inc. Transdermal administration of an enalapril ester
US6805878B2 (en) * 2001-09-13 2004-10-19 Noven Pharmaceuticals, Inc. Transdermal administration of ACE inhibitors
US20030082225A1 (en) * 2001-10-19 2003-05-01 Mason Paul Arthur Sterile, breathable patch for treating wound pain
US20030191185A1 (en) * 2001-10-29 2003-10-09 Franz G. Andrew Levothyroxine compositions having unique triiodothyronine Tmax properties
DE10157745A1 (de) * 2001-11-24 2003-06-26 Hf Arzneimittelforsch Gmbh Transdermales therapeutisches System zur Verabreichung von 17alpha-Estradiol
WO2003048579A2 (en) * 2001-12-04 2003-06-12 Kag Holding A/S Screw pump for transporting emulsions susceptible to mechanical handling
CN100594027C (zh) * 2001-12-05 2010-03-17 张喜田 番木鳖碱、马钱子碱和一叶秋碱及其盐的透皮剂
US20030147972A1 (en) * 2002-02-05 2003-08-07 Christopher W. Denver Method and composition for diminishing loss of color in flavors and fragrances
DK1482948T3 (da) * 2002-03-11 2006-11-27 Janssen Pharmaceutica Nv Kontinuerlig sulfataseinhiberende progestogen-hormonsubstitutionsbehandling
EP1482949A1 (en) * 2002-03-11 2004-12-08 Janssen Pharmaceutica N.V. Sulfatase inhibiting progestogen-only contraceptive regimens
US20030219471A1 (en) * 2002-03-11 2003-11-27 Caubel Patrick Michel Extended cycle estrogen and sulfatase inhibiting progestogen contraceptive regimens
DE10212864B4 (de) * 2002-03-22 2005-12-22 Beiersdorf Ag Polymermatrizes umfassend ein Mischsystem zur Löslichkeitsvermittlung von pharmazeutischen Wirkstoffen, Verfahren zu deren Herstellung und deren Verwendung
JP4478757B2 (ja) * 2002-04-19 2010-06-09 日東電工株式会社 ビソプロロール含有貼付剤
AR039336A1 (es) 2002-04-23 2005-02-16 Alza Corp Sistemas analgesicos transdermicos con potencial de abuso reducido
DE10220230A1 (de) * 2002-05-06 2003-11-27 Sanol Arznei Schwarz Gmbh Verwendung von Rotigotine zur Behandlung des Restless Leg Syndroms
AR033748A1 (es) * 2002-05-15 2004-01-07 Thalas Group Inc Un dispositivo para la administracion transdermica de sustancias farmacologicamente activas que comprende dos capas adhesivas superpuestas y un procedimiento para prepararlo
US7217853B2 (en) * 2002-05-24 2007-05-15 Corium International, Inc. Composition for cushions, wound dressings and other skin-contacting products
US20040018237A1 (en) * 2002-05-31 2004-01-29 Perricone Nicholas V. Topical drug delivery using phosphatidylcholine
US7097850B2 (en) * 2002-06-18 2006-08-29 Surmodics, Inc. Bioactive agent release coating and controlled humidity method
BRPI0312007B1 (pt) 2002-06-25 2015-04-14 Acrux Dds Pty Ltd Composição farmacêutica para administração transcutânea de testosterona ou fentanil e uso da dita composição
BR0312501A (pt) * 2002-07-10 2005-04-12 Warner Lambert Co Combinação de um inibidor alostérico ou metaloproteinase de matriz-13 com um inibidor de ciclooxigenase-2 diferente de celecoxib ou valdecoxib
US20040010035A1 (en) * 2002-07-15 2004-01-15 Ciociola Arthur A. Gastrointestinal compositions
US6986901B2 (en) * 2002-07-15 2006-01-17 Warner-Lambert Company Llc Gastrointestinal compositions
US8246979B2 (en) 2002-07-30 2012-08-21 Ucb Pharma Gmbh Transdermal delivery system for the administration of rotigotine
DE10234673B4 (de) * 2002-07-30 2007-08-16 Schwarz Pharma Ag Heißschmelz-TTS zur Verabreichung von Rotigotin und Verfahren zu seiner Herstellung sowie Verwendung von Rotigotin bei der Herstellung eines TTS im Heißschmelzverfahren
US8211462B2 (en) * 2002-07-30 2012-07-03 Ucb Pharma Gmbh Hot-melt TTS for administering rotigotine
US8246980B2 (en) * 2002-07-30 2012-08-21 Ucb Pharma Gmbh Transdermal delivery system
US6958142B2 (en) * 2002-08-02 2005-10-25 Balance Pharmaceuticals, Inc. Nasal spray formulation and method
JP4792193B2 (ja) * 2002-08-28 2011-10-12 久光製薬株式会社 貼付剤
AU2003268376A1 (en) * 2002-08-30 2004-11-26 Watson Pharmaceuticals, Inc. Transdermal delivery systems and methods
US20040086551A1 (en) 2002-10-30 2004-05-06 Miller Kenneth J. Fentanyl suspension-based silicone adhesive formulations and devices for transdermal delivery of fentanyl
ES2239196T3 (es) * 2002-12-02 2005-09-16 Schwarz Pharma Ag Suministro iontoforetico de rotigotina para el tratamiento de la enfermedad de parkinson.
DE10261696A1 (de) 2002-12-30 2004-07-15 Schwarz Pharma Ag Vorrichtung zur transdermalen Verabreichung von Rotigotin-Base
CN1738623A (zh) * 2003-01-23 2006-02-22 夏尔控股公司 治疗血小板增多症的制剂和方法
US20040147534A1 (en) * 2003-01-23 2004-07-29 Foote Mary Ann Topical composition and method for treating occlusive wounds
GB0302662D0 (en) * 2003-02-05 2003-03-12 Strakan Ltd Transdermal granisetron
DE10305137A1 (de) * 2003-02-07 2004-08-26 Novosis Ag Transdermale therapeutische Abgabesysteme mit einem Butenolid
US9498454B2 (en) * 2003-02-24 2016-11-22 Pharmaceutical Productions Inc. Transmucosal drug delivery system
JO2505B1 (en) 2003-03-14 2009-10-05 باير شيرنغ فارما اكتنجيسيلشافت Pharmacy methods and formulations for obtaining acceptable serum testosterone levels
US20040208917A1 (en) * 2003-04-16 2004-10-21 Wilfried Fischer Transdermal systems for the release of clonidine
ES2646813T3 (es) * 2003-06-19 2017-12-18 Coloplast A/S Un dispositivo para el cuidado de heridas
US7576226B2 (en) * 2003-06-30 2009-08-18 Richter Gedeon Vegyeszeti Gyar Rt. Process of making isomers of norelgestromin and methods using the same
US20120058993A1 (en) * 2003-07-23 2012-03-08 Douglas Pharmaceuticals Ltd. Stable Suspension Formulation
DE10334187A1 (de) * 2003-07-26 2005-03-03 Schwarz Pharma Ag Substituierte 2-Aminotetraline zur Behandlung von Depressionen
DE10334188B4 (de) * 2003-07-26 2007-07-05 Schwarz Pharma Ag Verwendung von Rotigotin zur Behandlung von Depressionen
US8815215B2 (en) 2003-08-15 2014-08-26 Colgate-Palmolive Company Hydrophobic tooth whitening system and methods of use
US20050036957A1 (en) 2003-08-15 2005-02-17 Michael Prencipe Tooth whitening dental tray and method of use
US20050187278A1 (en) * 2003-08-28 2005-08-25 Pharmacia Corporation Treatment or prevention of vascular disorders with Cox-2 inhibitors in combination with cyclic AMP-specific phosphodiesterase inhibitors
US8784874B2 (en) 2003-09-10 2014-07-22 Noven Pharmaceuticals, Inc. Multi-layer transdermal drug delivery device
WO2005033198A1 (en) * 2003-10-07 2005-04-14 Coloplast A/S A composition useful as an adhesive and use of such a composition
US20070009582A1 (en) * 2003-10-07 2007-01-11 Madsen Niels J Composition useful as an adhesive and use of such a composition
US7387788B1 (en) 2003-10-10 2008-06-17 Antares Pharma Ipl Ag Pharmaceutical compositions of nicotine and methods of use thereof
JP5619337B2 (ja) 2003-10-10 2014-11-05 フェリング ビー.ブイ. 皮膚残渣を最小限に抑えるための経皮的医薬製剤
JP2007509951A (ja) * 2003-10-28 2007-04-19 ノーヴェン ファーマシューティカルズ インコーポレイテッド 経皮的なドラッグデリバリーシステムにおける医薬品の損失及び送達を制御するための組成物及び方法
KR20060120678A (ko) * 2003-10-30 2006-11-27 알자 코포레이션 남용될 가능성이 감소된 경피용 진통제 시스템
MXPA06003769A (es) * 2003-11-04 2006-07-03 Shire Lab Inc Liberacion sostenida de moleculas farmacologicamente activas cargadas positivamente a partir de una matriz que contiene polimeros con atomos de oxigeno polarizados.
WO2005046663A1 (en) 2003-11-04 2005-05-26 Shire Laboratories, Inc. Compositions of quaternary ammonium containing bioavailability enhancers
ES2359375T3 (es) 2003-11-04 2011-05-20 Supernus Pharmaceuticals, Inc. Formas de dosificación de dosis única diaria de trospio.
CN101829319A (zh) 2003-12-08 2010-09-15 Cpex药品公司 用于胰岛素治疗的药用组合物及方法
KR20070007299A (ko) 2004-01-30 2007-01-15 코리움 인터네셔널, 인크. 활성제의 전달을 위한 급속 용해 필름
US20070128262A1 (en) * 2004-01-30 2007-06-07 Satoshi Amano Package containing adhesive patch and method of inhibiting drug migration
US20070149618A1 (en) 2004-02-17 2007-06-28 Action Medicines, S.L. Methods of use for 2,5-dihydroxybenzene sulfonic acid compounds for the treatment of cancer, rosacea and psoriasis
ES2238924B1 (es) 2004-02-17 2006-12-01 Investread Europa, S.L. Uso del acido 2,5-dihidroxibencenosulfonico, en la fabricacion de medicamentos de aplicacion en el tratamiento de enfermedades angiodependientes.
US20080125485A1 (en) 2004-02-17 2008-05-29 Action Medicines Use of 2,5-Dihydroxybenzene Derivatives for Treating Actinic Keratosis
US20050202073A1 (en) * 2004-03-09 2005-09-15 Mylan Technologies, Inc. Transdermal systems containing multilayer adhesive matrices to modify drug delivery
US9205062B2 (en) 2004-03-09 2015-12-08 Mylan Pharmaceuticals, Inc. Transdermal systems containing multilayer adhesive matrices to modify drug delivery
WO2005099786A1 (en) 2004-04-06 2005-10-27 Surmodics, Inc. Coating compositions for bioactive agents
JP2007532577A (ja) * 2004-04-07 2007-11-15 ダーマトレンズ,インコーポレイティド 塩基性浸透促進剤と共に用いるための経皮デリバリー・システム
WO2005102393A1 (ja) * 2004-04-21 2005-11-03 Hisamitsu Pharmaceutical Co., Inc. 粘着基剤中の吸収促進剤の含有率を高めた外用貼付剤
AU2005244214B2 (en) * 2004-04-29 2010-02-18 Teikoku Pharma Usa, Inc. Topical methadone compositions and methods for using the same
EP1743645A4 (en) * 2004-06-01 2012-11-14 Hisamitsu Pharmaceutical Co ADHESIVE PATCH
DE602005020393D1 (de) * 2004-06-01 2010-05-20 Hisamitsu Pharmaceutical Co Adhäsive Pflaster
US20060024246A1 (en) * 2004-07-29 2006-02-02 Prithwiraj Maitra Oral care compositions with film forming polymers
US20060030574A1 (en) * 2004-08-04 2006-02-09 Shire Holdings Ag Quinazoline derivatives useful for the treatment of peripheral arterial disease and as phosphodiesterase inhibitors
US7700608B2 (en) * 2004-08-04 2010-04-20 Shire Holdings Ag Quinazoline derivatives and their use in the treatment of thrombocythemia
CN103497713B (zh) 2004-08-05 2018-07-17 考里安国际公司 粘合剂组合物
WO2006036899A2 (en) * 2004-09-27 2006-04-06 Corium International, Inc. Transdermal systems for the delivery of estrogens and progestins
WO2006041907A2 (en) 2004-10-08 2006-04-20 Noven Pharmaceuticals, Inc. Transdermal delivery of estradiol
US20060078604A1 (en) * 2004-10-08 2006-04-13 Noven Pharmaceuticals, Inc. Transdermal drug delivery device including an occlusive backing
WO2006041911A2 (en) * 2004-10-08 2006-04-20 Noven Pharmaceuticals, Inc. Device transdermal administration of drugs including acrylic polymers
TW200616589A (en) * 2004-10-08 2006-06-01 Noven Pharma Transdermal delivery of drugs based on crystal size
JP2008517142A (ja) * 2004-10-19 2008-05-22 スリーエム イノベイティブ プロパティズ カンパニー 感圧接着剤の製造方法
EP2216018B1 (en) 2004-10-21 2012-04-04 Durect Corporation Transdermal delivery systems
US8252320B2 (en) 2004-10-21 2012-08-28 Durect Corporation Transdermal delivery system for sufentanil
KR100810947B1 (ko) * 2005-01-28 2008-03-10 롬 앤드 하아스 컴패니 에멀젼 폴리머로부터 제조된 의료용 필름 및 제품
EP1847264B1 (en) * 2005-01-31 2017-05-03 Hisamitsu Pharmaceutical Co., Inc. Bisoprolol patch
JP4704764B2 (ja) * 2005-02-03 2011-06-22 日東電工株式会社 爪貼付用粘着組成物および爪用貼付剤
US20080138388A1 (en) * 2005-02-04 2008-06-12 Hisamitsu Pharmaceutical Co., Inc. Transdermal Absorption Patch
FR2881653A1 (fr) * 2005-02-04 2006-08-11 Frederic Khodja Dispositif permettant l'administration en continu d'une dose physiologique controlee d'au moins un mineral ou une vitamine
ATE476970T1 (de) 2005-02-18 2010-08-15 Universitaetsklinikum Freiburg Kontrolle der androgen rezeptor-abhängigen gen expression durch hemmung der aminoxidase aktivität der lysin spezifischen demethylase (lsd1)
TW200640526A (en) * 2005-02-24 2006-12-01 Alza Corp Transdermal electrotransport drug delivery systems with reduced abuse potential
JP4873871B2 (ja) * 2005-02-28 2012-02-08 久光製薬株式会社 粘着剤及び貼付剤
US7914810B2 (en) * 2005-05-06 2011-03-29 Synthes Usa, Llc Methods for the in situ treatment of bone cancer
ES2785999T3 (es) * 2005-05-16 2020-10-08 Novapharm Res Australia Pty Limited Composición para su uso en la preparación de un paciente para cirugía
US20060263421A1 (en) * 2005-05-18 2006-11-23 Abeille Pharmaceuticals Inc Transdermal Method and Patch for Nausea
US8277780B2 (en) * 2005-05-27 2012-10-02 Taro Pharmaceutical North America, Inc. Stable liquid desoximethasone compositions with reduced oxidized impurity
WO2006125642A1 (en) 2005-05-27 2006-11-30 Antares Pharma Ipl Ag Methods and apparatus for transdermal or transmucosal application of testosterone
CA2611224C (en) * 2005-06-10 2014-01-21 3M Innovative Properties Company Method for handling adhesive laminate sections
US20060281775A1 (en) * 2005-06-14 2006-12-14 Applied Pharmacy Services, Inc. Two-component pharmaceutical composition for the treatment of pain
ATE477833T1 (de) 2005-06-27 2010-09-15 3M Innovative Properties Co Mikronadelkartuschenanordnung
JP5058531B2 (ja) 2005-09-09 2012-10-24 日東電工株式会社 ビソプロロール含有貼付製剤
EP2308480B1 (en) 2005-09-23 2014-08-13 ALZA Corporation High Enhancer-Loading Polyacrylate Formulation for Transdermal Applications
US9056061B2 (en) * 2005-09-23 2015-06-16 Alza Corporation Transdermal nicotine salt delivery system
WO2007035941A2 (en) * 2005-09-23 2007-03-29 Alza Corporation Transdermal galantamine delivery system
US20090130188A9 (en) * 2005-09-29 2009-05-21 National Starch And Chemical Investment Holding Company Acrylic pressure sensitive adhesives
PT1937276E (pt) 2005-10-12 2013-02-21 Besins Healthcare Luxembourg Gel de testosterona melhorado e método para a sua utilização
US20070087055A1 (en) * 2005-10-14 2007-04-19 David Jan Directly compressible extended release alprazolam formulation
CN101370486B (zh) * 2005-12-09 2012-12-05 北京康倍得医药技术开发有限公司 含有硝酸异山梨酯和比索洛尔的透皮贴剂
JP4945228B2 (ja) 2005-12-13 2012-06-06 日東電工株式会社 ビソプロロール含有貼付製剤
JP5801528B2 (ja) * 2005-12-14 2015-10-28 スリーエム イノベイティブ プロパティズ カンパニー 抗菌接着フィルム
US8124169B2 (en) * 2005-12-14 2012-02-28 3M Innovative Properties Company Antimicrobial coating system
US20070138439A1 (en) * 2005-12-21 2007-06-21 3M Innovative Properties Company Denaturant for ethanol
SE530184C2 (sv) * 2005-12-23 2008-03-18 Kjell Stenberg Bioadhesiv farmaceutisk filmkomposition innehållande lågviskösa alginater
FR2895679B1 (fr) * 2005-12-29 2012-06-08 Pf Medicament Stabilisation de testosterone au sein de dispositifs transdermiques
WO2007095147A2 (en) * 2006-02-13 2007-08-23 Aveva Drug Delivery Systems Adhesive preparation comprising sufentanil and methods of using the same
JP5037831B2 (ja) * 2006-02-15 2012-10-03 久光製薬株式会社 凝集力向上及び徐放化の外用貼付剤
EP1998756A2 (en) * 2006-02-27 2008-12-10 Noven Pharmaceuticals, Inc. Compositions and methods for delivery of amino-functional drugs
EP1992363B1 (en) * 2006-02-28 2012-12-19 Hisamitsu Pharmaceutical Co., Inc. Transdermal absorption preparation
DE102006019293A1 (de) * 2006-04-21 2007-10-25 LABTEC Gesellschaft für technologische Forschung und Entwicklung mbH Pflaster, enthaltend ein Fentanyl Analogum
CA2646667C (en) 2006-04-21 2014-03-11 Antares Pharma Ipl Ag Methods of treating hot flashes with formulations for transdermal or transmucosal application
US8758739B2 (en) * 2006-05-03 2014-06-24 L'oreal Cosmetic compositions containing block copolymers, tackifiers and gelling agents
US8673284B2 (en) * 2006-05-03 2014-03-18 L'oreal Cosmetic compositions containing block copolymers, tackifiers and a selective solvent for hard blocks
US8673283B2 (en) * 2006-05-03 2014-03-18 L'oreal Cosmetic compositions containing block copolymers, tackifiers and a solvent mixture
US8673282B2 (en) * 2006-05-03 2014-03-18 L'oreal Cosmetic compositions containing block copolymers, tackifiers and a selective solvent for soft blocks
US8778323B2 (en) * 2006-05-03 2014-07-15 L'oréal Cosmetic compositions containing block copolymers, tackifiers and modified silicones
US8557230B2 (en) * 2006-05-03 2013-10-15 L'oreal Cosmetic compositions containing block copolymers, tackifiers and shine enhancing agents
US8614278B2 (en) 2006-06-06 2013-12-24 Dow Corning Corporation Silicone acrylate hybrid composition and method of making same
WO2007145996A2 (en) * 2006-06-06 2007-12-21 Dow Corning Corporation A silicone acrylate hybrid composition
US8569416B2 (en) 2006-06-06 2013-10-29 Dow Corning Corporation Single phase silicone acrylate formulation
US20070287727A1 (en) * 2006-06-08 2007-12-13 Jacob Hiller Anti-Nicotine Treatment
US9386770B2 (en) * 2006-06-13 2016-07-12 Phibro Animal Health Corp. Use of predissolved pristinamycin-type and polyether ionophore type antimicrobial agents in the production of ethanol
WO2008001204A2 (en) * 2006-06-29 2008-01-03 Antares Pharma Ipl Ag Transdermal compositions of pramipexole having enhanced permeation properties
TW200815045A (en) * 2006-06-29 2008-04-01 Jazz Pharmaceuticals Inc Pharmaceutical compositions of ropinirole and methods of use thereof
WO2008008281A2 (en) 2006-07-07 2008-01-17 Proteus Biomedical, Inc. Smart parenteral administration system
US10208158B2 (en) 2006-07-10 2019-02-19 Medipacs, Inc. Super elastic epoxy hydrogel
WO2008007554A1 (fr) * 2006-07-14 2008-01-17 Hisamitsu Pharmaceutical Co., Inc. Préparation d'adhésif
US7731604B2 (en) * 2006-10-31 2010-06-08 Taylor Made Golf Company, Inc. Golf club iron head
DE102006054731B4 (de) 2006-11-21 2013-02-28 Lts Lohmann Therapie-Systeme Ag Transdermales therapeutisches System zur Verabreichung des Wirkstoffs Buprenorphin und Verwendung desselben in der Schmerztherapie
US7910597B2 (en) * 2006-11-28 2011-03-22 Shire Llc Substituted quinazolines
US8304420B2 (en) 2006-11-28 2012-11-06 Shire Llc Substituted quinazolines for reducing platelet count
US8658141B2 (en) * 2007-01-12 2014-02-25 L'oreal Cosmetic composition containing a block copolymer, a tackifier, a silsesquioxane wax and/or resin
US8603444B2 (en) * 2007-01-12 2013-12-10 L'oréal Cosmetic compositions containing a block copolymer, a tackifier and a high viscosity ester
KR20090118957A (ko) 2007-03-08 2009-11-18 닛토덴코 가부시키가이샤 비소프롤롤 경피 투여 디바이스
WO2008116004A2 (en) 2007-03-19 2008-09-25 Vita Sciences, Llc Transdermal patch and method for delivery of vitamin b12
DE102007020799A1 (de) 2007-05-03 2008-11-06 Novosis Ag Transdermales therapeutisches System mit Remifentanil
EP2167105A1 (en) * 2007-06-13 2010-03-31 3M Innovative Properties Company Antimicrobial film-forming composition, antimicrobial film, and method of verifying the presence of an antimicrobial film
CN101147739B (zh) * 2007-07-06 2010-12-08 北京康倍得医药技术开发有限公司 含罗替戈汀的组合物及其制药用途以及含该组合物的透皮贴剂
AU2008289109B2 (en) * 2007-08-17 2012-02-02 Centrexion Therapeutics Corporation High concentration local anesthetic formulations
KR101583680B1 (ko) * 2007-10-15 2016-01-08 알자 코퍼레이션 펜타닐의 1일-1회 교체 경피 투여
EP2211974A4 (en) 2007-10-25 2013-02-27 Proteus Digital Health Inc INFORMATION SYSTEM FOR LIQUID FLOW CHANNEL
US8419638B2 (en) 2007-11-19 2013-04-16 Proteus Digital Health, Inc. Body-associated fluid transport structure evaluation devices
CL2008003507A1 (es) 2007-11-26 2009-11-27 Neuroderm Ltd Composicion farmaceutica que comprende nicotina y un inhibidor de la desensibilizacion del receptor de acetilcolina nicotinico (nachr) opipramol; kit farmaceutico; dispositivo medico; y uso para tratar una enfermedad o trastorno del sistema nervioso central o periferico.
WO2009073734A2 (en) 2007-12-03 2009-06-11 Medipacs, Inc. Fluid metering device
DE102008013701A1 (de) * 2008-03-11 2009-09-17 Lts Lohmann Therapie-Systeme Ag Transdermales Therapeutisches System mit stabilisierter Membran
CA2662499A1 (en) 2008-04-16 2009-10-16 Nitto Denko Corporation Transdermal drug administration device
EP2111857A1 (de) * 2008-04-25 2009-10-28 Acino AG Transdermales therapeutisches System zur Verabreichung von Fentanyl oder einem Analogstoff hiervon
NZ589542A (en) * 2008-05-30 2012-10-26 Mylan Inc Transdermal drug delivery system comprising an active agent in amorphous form and polyvinylpyrrolidone
JP5368168B2 (ja) * 2008-06-16 2013-12-18 日東電工株式会社 貼付剤及び貼付製剤
US20090318520A1 (en) * 2008-06-20 2009-12-24 Afecta Pharmaceuticals Drive Use of isoindoles for the treatment of neurobehavioral disorders
US8231906B2 (en) 2008-07-10 2012-07-31 Noven Pharmaceuticals, Inc. Transdermal estrogen device and delivery
WO2010006292A1 (en) * 2008-07-11 2010-01-14 Neumedics Tetracycline derivatives with reduced antibiotic activity and neuroprotective benefits
US8734944B2 (en) * 2008-07-28 2014-05-27 Dow Corning Corporation Composite article
WO2010019953A1 (en) 2008-08-15 2010-02-18 Arcion Therapeutics, Inc. High concentration local anesthetic formulations for treating non-neuropathic pain
EP2328561B1 (en) * 2008-08-19 2015-11-25 Adcock Ingram Intellectual Property (Pty) Limited Rate Modulated Delivery of Drugs from a Three-Layer Tablet Comprising Tramadol, Diclofenac, Paracetamol
JP5704801B2 (ja) * 2008-08-21 2015-04-22 ニプロパッチ株式会社 粘着性組成物及び経皮吸収型製剤
CA2735418A1 (en) * 2008-08-26 2010-03-11 Ray L. Hauser Substance delivery to skin and other tissues
CA2738524C (en) 2008-10-02 2013-11-26 Mylan Inc. Method for making a multilayer adhesive laminate
WO2010083035A2 (en) 2009-01-14 2010-07-22 Corium International, Inc. Transdermal administration of tamsulosin
JP5664991B2 (ja) * 2009-03-27 2015-02-04 トーアエイヨー株式会社 経皮吸収製剤
KR101452788B1 (ko) 2009-04-24 2014-10-21 헨켈 유에스 아이피 엘엘씨 실리콘 아크릴 혼성 중합체-기재 접착제
US20100298335A1 (en) * 2009-05-22 2010-11-25 Kaufman Herbert E Preparations and Methods for Ameliorating or Reducing Presbyopia
US8299079B2 (en) 2009-05-22 2012-10-30 Kaufman Herbert E Preparations and methods for ameliorating or reducing presbyopia
JP5281973B2 (ja) * 2009-07-06 2013-09-04 日東電工株式会社 ビソプロロール含有貼付剤
CN101618030B (zh) * 2009-08-10 2010-12-29 辽宁亿灵科创生物医药科技有限公司 一种雷公藤内酯醇透皮贴剂及其制备方法
US20110037455A1 (en) * 2009-08-17 2011-02-17 Oren Navot System for measuring electrical power
US20090318568A1 (en) * 2009-08-26 2009-12-24 Hauser Ray L Adherent coating for tissue surface and/or trans-tissue surface substance delivery
WO2011032011A1 (en) 2009-09-10 2011-03-17 Medipacs, Inc. Low profile actuator and improved method of caregiver controlled administration of therapeutics
US8221994B2 (en) * 2009-09-30 2012-07-17 Cilag Gmbh International Adhesive composition for use in an immunosensor
US8551781B2 (en) 2009-11-19 2013-10-08 The Regents Of The University Of California Vault complexes for facilitating biomolecule delivery
CN102666714B (zh) 2009-11-19 2015-04-29 3M创新有限公司 包含合成橡胶和与丙烯酸类聚合物结合的官能化合成橡胶的共混物的压敏粘合剂
JP5695658B2 (ja) 2009-11-19 2015-04-08 スリーエム イノベイティブ プロパティズ カンパニー アクリルポリマーに水素結合した官能化ポリイソブチレンを含む感圧性接着剤
US9320742B2 (en) * 2009-12-01 2016-04-26 Noven Pharmaceuticals, Inc. Transdermal testosterone device and delivery
EA025584B1 (ru) 2009-12-22 2017-01-30 ЮСиБи ФАРМА ГМБХ Поливинилпирролидон для стабилизации твердой дисперсии некристаллической формы ротиготина
US20110172637A1 (en) * 2010-01-08 2011-07-14 Ratio, Inc. Drug delivery device including tissue support structure
US20110172645A1 (en) * 2010-01-08 2011-07-14 Ratio, Inc. Wearable drug delivery device including integrated pumping and activation elements
US20110172609A1 (en) * 2010-01-08 2011-07-14 Ratio, Inc. Microneedle component assembly for drug delivery device
US20110172639A1 (en) * 2010-01-08 2011-07-14 Ratio, Inc. Device and method for delivery of microneedle to desired depth within the skin
JP5330609B2 (ja) 2010-02-01 2013-10-30 プロテウス デジタル ヘルス, インコーポレイテッド 2つの手首におけるデータ収集システム
MX2012008922A (es) 2010-02-01 2012-10-05 Proteus Digital Health Inc Sistema de recoleccion de datos.
US9500186B2 (en) 2010-02-01 2016-11-22 Medipacs, Inc. High surface area polymer actuator with gas mitigating components
DE102010026879A1 (de) 2010-02-11 2011-08-11 AMW GmbH, 83627 Transdermales System mit Immunmodulator
DE102010026883A1 (de) 2010-03-11 2011-12-15 Amw Gmbh Transdermales System mit Aromatasehemmer
JP5927506B2 (ja) 2010-04-13 2016-06-01 レルマダ セラピューティクス、インク. 1−メチル−2’,6’−ピペコロキシリダイドの皮膚医薬組成物および使用方法
DE102011100619A1 (de) 2010-05-05 2012-01-05 Amw Gmbh Transdermales therapeutisches System (TTS) mit einem Gehalt an einem Opiod-Analgetikum
DE102010024105A1 (de) * 2010-06-17 2011-12-22 Grünenthal GmbH Transdermale Verabreichung von Memantin
DE102010026903A1 (de) 2010-07-12 2012-01-12 Amw Gmbh Transdermales therapeutisches System mit Avocadoöl oder Palmöl als Hilfsstoff
CA2807336A1 (en) 2010-08-05 2012-02-09 Biofilm Ip, Llc Cyclosiloxane-substituted polysiloxane compounds, compositions containing the compounds and methods of use thereof
US8668675B2 (en) 2010-11-03 2014-03-11 Flugen, Inc. Wearable drug delivery device having spring drive and sliding actuation mechanism
WO2012092165A1 (en) 2010-12-29 2012-07-05 Noven Pharmaceuticals, Inc. Transdermal drug delivery system comprising levonorgestrel acetate
US20120219516A1 (en) 2011-02-25 2012-08-30 L'oreal S.A. Cosmetic compositions having long lasting shine
KR20120107153A (ko) * 2011-03-15 2012-10-02 아이큐어 주식회사 펜타닐 경피 패치제
CN103547258B (zh) 2011-03-17 2017-10-20 特兰斯德梅尔生物工艺股份有限公司 局部一氧化氮系统及其使用方法
US9925264B2 (en) 2011-05-10 2018-03-27 Itochu Chemical Frontier Corporation Non-aqueous patch
US11786455B2 (en) 2011-05-10 2023-10-17 Itochu Chemical Frontier Corporation Non-aqueous patch
BR112013028802B1 (pt) * 2011-05-10 2021-10-26 Itochu Chemical Frontier Corporation Curativo adesivo não-aquoso
WO2012165254A1 (ja) * 2011-05-31 2012-12-06 久光製薬株式会社 ロピニロール含有貼付剤及びその包装体
ITMI20111355A1 (it) * 2011-07-20 2013-01-21 Epifarma Srl Cerotto transdermico contenente diclofenac e tiocolchicoside
LT2823815T (lt) 2011-09-27 2018-08-27 Itochu Chemical Frontier Corporation Nevandeninis pleistras
EP2584016A1 (en) 2011-10-21 2013-04-24 Dow Corning Corporation Single phase silicone acrylate formulation
CA2854164C (en) * 2011-11-04 2021-04-13 Agile Therapeutics, Inc. Dermal delivery compositions and methods
US9301920B2 (en) 2012-06-18 2016-04-05 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
HUE055562T2 (hu) 2011-11-23 2021-11-29 Therapeuticsmd Inc Természetes kombinációjú hormon helyettesítõ kiszerelések, és terápiák ezekkel
JP2013139554A (ja) 2011-11-29 2013-07-18 Dow Corning Corp シリコーンアクリレートハイブリッド組成物及び該組成物の製造方法
US9849270B2 (en) 2011-12-16 2017-12-26 3M Innovative Properties Company Foldable adhesive composite dressing
US10426739B2 (en) 2011-12-21 2019-10-01 3M Innovative Properties Company Adhesive patch assembly with overlay liner and system and method for making same
WO2013096026A1 (en) 2011-12-21 2013-06-27 3M Innovative Properties Company Transdermal adhesive patch assembly with removable microneedle array and method of using same
DE102011090178A1 (de) 2011-12-30 2013-07-04 Lts Lohmann Therapie-Systeme Ag Transdermales therapeutisches System mit geringer Neigung zur Spontankristallisation
CN104302689A (zh) 2012-03-14 2015-01-21 麦德医像公司 含有过量活性分子的智能聚合物材料
US9084839B2 (en) 2012-03-27 2015-07-21 Berry Plastics Corporation Adhesive for use on skin
DE102012205493A1 (de) * 2012-04-03 2013-10-10 Acino Ag Einen Dopamin-Agonisten enthaltendes transdermales Applikationssystem
EP2845241A4 (en) 2012-05-02 2016-02-10 Henkel US IP LLC CURABLE ENCAPSULATION AGENTS AND USE THEREOF
US20150196640A1 (en) 2012-06-18 2015-07-16 Therapeuticsmd, Inc. Progesterone formulations having a desirable pk profile
US10806697B2 (en) 2012-12-21 2020-10-20 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US20130338122A1 (en) 2012-06-18 2013-12-19 Therapeuticsmd, Inc. Transdermal hormone replacement therapies
US10806740B2 (en) 2012-06-18 2020-10-20 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US8871255B2 (en) 2012-09-19 2014-10-28 Transdermal Biotechnology, Inc. Treatment of skin and soft tissue infection with nitric oxide
US8871260B2 (en) 2012-09-19 2014-10-28 Transdermal Biotechnology, Inc. Methods and compositions for muscular and neuromuscular diseases
US8871262B2 (en) 2012-09-19 2014-10-28 Transdermal Biotechnology, Inc. Compositions and methods for treatment of osteoporosis and other indications
US8871261B2 (en) 2012-09-19 2014-10-28 Transdermal Biotechnology, Inc. Cancer treatments and compositions for use thereof
US8871254B2 (en) 2012-09-19 2014-10-28 Transdermal Biotechnology, Inc. Systems and methods for treatment of acne vulgaris and other conditions with a topical nitric oxide delivery system
US8871256B2 (en) 2012-09-19 2014-10-28 Transdermal Biotechnology, Inc. Methods and systems for treatment of inflammatory diseases with nitric oxide
US8871259B2 (en) 2012-09-19 2014-10-28 Transdermal Biotechnology, Inc. Techniques and systems for treatment of neuropathic pain and other indications
US8871257B2 (en) 2012-09-19 2014-10-28 Transdermal Biotechnology, Inc. Prevention and treatment of cardiovascular diseases using systems and methods for transdermal nitric oxide delivery
US8871258B2 (en) 2012-09-19 2014-10-28 Transdermal Biotechnology, Inc. Treatment and prevention of learning and memory disorders
WO2014058746A1 (en) 2012-10-10 2014-04-17 3M Innovative Properties Company Force-controlled applicator for applying a microneedle device to skin
EP2906285B1 (en) 2012-10-10 2019-06-12 3M Innovative Properties Company Applicator for applying a microneedle device to skin
WO2014062494A1 (en) 2012-10-15 2014-04-24 Noven Pharmaceuticals, Inc. Compositions and methods for the transdermal delivery of methylphenidate
CN104797287B (zh) 2012-11-16 2017-12-26 3M创新有限公司 力控施用装置
TW201431570A (zh) 2012-11-22 2014-08-16 Ucb Pharma Gmbh 用於經皮投服羅替戈汀(Rotigotine)之多天式貼片
US20140172118A1 (en) * 2012-12-19 2014-06-19 Cook Medical Technologies Llc Bioactive Compositions, Bioactive Eluting Devices and Methods of Use Thereof
US9180091B2 (en) 2012-12-21 2015-11-10 Therapeuticsmd, Inc. Soluble estradiol capsule for vaginal insertion
US11246875B2 (en) 2012-12-21 2022-02-15 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10537581B2 (en) 2012-12-21 2020-01-21 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10471072B2 (en) 2012-12-21 2019-11-12 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11266661B2 (en) 2012-12-21 2022-03-08 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10568891B2 (en) 2012-12-21 2020-02-25 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
JP2016505006A (ja) 2012-12-28 2016-02-18 ノーヴェン ファーマシューティカルズ インコーポレイテッド レボノルゲストレル及びエチニルエストラジオール用の経皮薬物送達システム
MX2015008284A (es) * 2012-12-28 2015-12-03 Noven Pharma Composiciones y metodos para suministro transdermico de agentes no esteroidales anti-inflamatorios.
EP2938335B1 (en) 2012-12-28 2021-03-17 Noven Pharmaceuticals, INC. Multi-polymer compositions for transdermal drug delivery
CA2896055C (en) 2012-12-28 2021-02-16 Noven Pharmaceuticals, Inc. Compositions and methods for transdermal delivery of amphetamine and clonidine
US9072682B2 (en) 2012-12-31 2015-07-07 Mylan Inc. Transdermal dosage form for low-melting point active agent
WO2014130846A1 (en) 2013-02-22 2014-08-28 Seungpyo Hong Transdermal drug delivery using amphiphilic dendron-coil micelles
US9339457B2 (en) 2013-03-13 2016-05-17 Transdermal Biotechnology, Inc. Cardiovascular disease treatment and prevention
US9314423B2 (en) 2013-03-13 2016-04-19 Transdermal Biotechnology, Inc. Hair treatment systems and methods using peptides and other compositions
US9314417B2 (en) 2013-03-13 2016-04-19 Transdermal Biotechnology, Inc. Treatment of skin, including aging skin, to improve appearance
US9724419B2 (en) 2013-03-13 2017-08-08 Transdermal Biotechnology, Inc. Peptide systems and methods for metabolic conditions
US20140271937A1 (en) 2013-03-13 2014-09-18 Transdermal Biotechnology, Inc. Brain and neural treatments comprising peptides and other compositions
US20140271731A1 (en) 2013-03-13 2014-09-18 Transdermal Biotechnology, Inc. Cardiovascular disease treatment and prevention
US9320706B2 (en) 2013-03-13 2016-04-26 Transdermal Biotechnology, Inc. Immune modulation using peptides and other compositions
US9295637B2 (en) 2013-03-13 2016-03-29 Transdermal Biotechnology, Inc. Compositions and methods for affecting mood states
US20140271938A1 (en) 2013-03-13 2014-09-18 Transdermal Biotechnology, Inc. Systems and methods for delivery of peptides
EP2968652B1 (en) 2013-03-13 2020-07-22 Avery Dennison Corporation Improving adhesive properties
US9750787B2 (en) 2013-03-13 2017-09-05 Transdermal Biotechnology, Inc. Memory or learning improvement using peptide and other compositions
US9687520B2 (en) 2013-03-13 2017-06-27 Transdermal Biotechnology, Inc. Memory or learning improvement using peptide and other compositions
US9314422B2 (en) 2013-03-13 2016-04-19 Transdermal Biotechnology, Inc. Peptide systems and methods for metabolic conditions
US9241899B2 (en) 2013-03-13 2016-01-26 Transdermal Biotechnology, Inc. Topical systems and methods for treating sexual dysfunction
US9295647B2 (en) 2013-03-13 2016-03-29 Transdermal Biotechnology, Inc. Systems and methods for delivery of peptides
US9314433B2 (en) 2013-03-13 2016-04-19 Transdermal Biotechnology, Inc. Methods and systems for treating or preventing cancer
US9849160B2 (en) 2013-03-13 2017-12-26 Transdermal Biotechnology, Inc. Methods and systems for treating or preventing cancer
US9393264B2 (en) 2013-03-13 2016-07-19 Transdermal Biotechnology, Inc. Immune modulation using peptides and other compositions
US9393265B2 (en) 2013-03-13 2016-07-19 Transdermal Biotechnology, Inc. Wound healing using topical systems and methods
WO2014159801A1 (en) * 2013-03-13 2014-10-02 Avery Dennison Corporation Enhanced drug delivery from adhesives
US9295636B2 (en) 2013-03-13 2016-03-29 Transdermal Biotechnology, Inc. Wound healing using topical systems and methods
US9320758B2 (en) 2013-03-13 2016-04-26 Transdermal Biotechnology, Inc. Brain and neural treatments comprising peptides and other compositions
US9387159B2 (en) 2013-03-13 2016-07-12 Transdermal Biotechnology, Inc. Treatment of skin, including aging skin, to improve appearance
WO2014159582A1 (en) 2013-03-14 2014-10-02 Noven Pharmaceuticals, Inc Amphetamine transdermal compositions with acrylic block copolymer
AR095260A1 (es) 2013-03-15 2015-09-30 Noven Pharma Composiciones de anfetaminas transdérmicas estables y métodos de fabricación
AR095259A1 (es) 2013-03-15 2015-09-30 Noven Pharma Composiciones y métodos para la administración transdérmica de fármacos de amina terciaria
SG11201507885TA (en) 2013-03-22 2015-11-27 3M Innovative Properties Co Microneedle applicator comprising a counter assembly
WO2014188329A2 (en) * 2013-05-20 2014-11-27 Mylan, Inc. Transdermal therapeutic system for extended dosing of pramipexole in treating neurological disorders
EP3003459B1 (en) 2013-05-31 2018-06-20 3M Innovative Properties Company Microneedle injection apparatus comprising an inverted actuator
EP3003457B8 (en) 2013-05-31 2021-02-24 Kindeva Drug Delivery L.P. Microneedle injection and infusion apparatus
US9895520B2 (en) 2013-05-31 2018-02-20 3M Innovative Properties Company Microneedle injection apparatus comprising a dual cover
JP5415645B1 (ja) 2013-06-28 2014-02-12 久光製薬株式会社 貼付剤の製造方法、貼付剤及び包装体
WO2015001012A1 (de) 2013-07-03 2015-01-08 Lts Lohmann Therapie-Systeme Ag Transdermales therapeutisches system mit elektronischem bauteil
ITTO20130663A1 (it) * 2013-08-02 2015-02-03 Abc Farmaceutici S P A Sistema di somministrazione transdermico per l'impiego nel trattamento di patologie croniche bronco-polmonari
WO2015023649A2 (en) 2013-08-12 2015-02-19 3M Innovative Properties Company Peptides for enhancing transdermal delivery
EP3038608B1 (en) * 2013-08-30 2018-01-03 3M Innovative Properties Company Estradiol containing transdermal drug delivery systems and compositions
WO2015054059A2 (en) 2013-10-07 2015-04-16 Teikoku Pharma Usa, Inc. Methods and compositions for treating attention deficit hyperactivity disorder, anxiety and insomnia using dexmedetomidine transdermal compositions
CN105764494A (zh) 2013-10-07 2016-07-13 帝国制药美国公司 右旋美托咪啶经皮递送装置及其使用方法
EP3054930B1 (en) 2013-10-07 2020-12-02 Teikoku Pharma USA, Inc. Methods and compositions for transdermal delivery of a non-sedative amount of dexmedetomidine
WO2015177204A1 (en) 2014-05-20 2015-11-26 Lts Lohmann Therapie-Systeme Ag Transdermal delivery system containing rotigotine
US11752110B2 (en) * 2014-05-20 2023-09-12 Lts Lohmann Therapie-Systeme Ag Transdermal delivery system including an interface mediator
EP3145503A1 (en) 2014-05-20 2017-03-29 LTS Lohmann Therapie-Systeme AG Method for adjusting the release of active agent in a transdermal delivery system
RU2016143081A (ru) 2014-05-22 2018-06-26 Терапьютиксмд, Инк. Натуральные комбинированные гормонозаместительные составы и терапии
EP3020398A1 (en) 2014-11-17 2016-05-18 Nitto Denko Corporation Compounds and formulations for reducing scarring
US10028904B2 (en) 2014-12-04 2018-07-24 Wisconsin Alumni Research Foundation Transdermal cannabinoid formulations
US9375417B2 (en) 2014-12-04 2016-06-28 Mary's Medicinals LLC Transdermal cannabinoid formulations
CN107107598B (zh) 2014-12-18 2019-11-22 3M创新有限公司 处理粘合层合物贴剂的方法
US10406116B2 (en) 2015-02-06 2019-09-10 Noven Pharmaceuticals, Inc. Pressure-sensitive adhesives for transdermal drug delivery
JP6807848B2 (ja) 2015-02-06 2021-01-06 ノーヴェン ファーマシューティカルズ インコーポレイテッド 経皮薬物送達のための感圧粘着剤
WO2016149077A2 (en) * 2015-03-13 2016-09-22 Amneal Pharmaceuticals Llc Fentanyl transdermal delivery system
US20180169034A1 (en) 2015-06-14 2018-06-21 Trs Ii, Llc Transdermal delivery formulation
WO2017004507A1 (en) 2015-07-02 2017-01-05 Noven Pharmaceuticals, Inc. Transdermal drug delivery systems for levonorgestrel and ethinyl estradiol
US10328087B2 (en) 2015-07-23 2019-06-25 Therapeuticsmd, Inc. Formulations for solubilizing hormones
CN107921141A (zh) * 2015-08-27 2018-04-17 东洋油墨Sc控股株式会社 贴剂
CN108601749A (zh) 2016-02-05 2018-09-28 3M创新有限公司 具有氟代硅氧烷剥离衬件的透皮药物递送体系
US10286077B2 (en) 2016-04-01 2019-05-14 Therapeuticsmd, Inc. Steroid hormone compositions in medium chain oils
KR20180126582A (ko) 2016-04-01 2018-11-27 쎄러퓨틱스엠디, 인코퍼레이티드 스테로이드 호르몬 약제학적 조성물
WO2017223402A1 (en) 2016-06-23 2017-12-28 Corium International, Inc. Adhesive matrix with hydrophilic and hydrophobic domains and a therapeutic agent
US9650338B1 (en) 2016-07-29 2017-05-16 VDM Biochemicals, Inc. Opioid antagonist compounds and methods of making and using
EP3287462A1 (en) 2016-08-25 2018-02-28 Nitto Denko Corporation Isosorbide derivatives to treat bacterial biofilms
MX2019007389A (es) 2016-12-20 2019-08-16 Lts Lohmann Therapie Systeme Ag Sistema terapeutico transdermico que contiene asenapina y polisiloxano o poliisobutileno.
US20180193283A1 (en) 2016-12-20 2018-07-12 Lts Lohmann Therapie-Systeme Ag Transdermal therapeutic system containing asenapine
DE102017104026A1 (de) 2017-02-27 2018-08-30 Lts Lohmann Therapie-Systeme Ag Nicotin enthaltendes transparentes transdermales therapeutisches System
JP2020525545A (ja) 2017-06-26 2020-08-27 エルテーエス ローマン テラピー−ジステーメ アーゲー アセナピンおよびシリコーンアクリルハイブリッドポリマーを含有する経皮治療システム
ES2954714T3 (es) 2017-10-11 2023-11-23 Lts Lohmann Therapie Systeme Ag Sistema terapéutico transdérmico para la administración transdérmica de guanfacina que comprende un polímero híbrido acrílico de silicona
WO2019072997A1 (en) * 2017-10-11 2019-04-18 Lts Lohmann Therapie-Systeme Ag TRANSDERMAL THERAPEUTIC SYSTEM FOR TRANSDERMAL GUANFACIN ADMINISTRATION COMPRISING A SILICONE POLYMER
EP3694498A1 (en) * 2017-10-11 2020-08-19 LTS Lohmann Therapie-Systeme AG Transdermal therapeutic system for the transdermal administration of guanfacine comprising at least one additive
EP3775086B1 (en) 2018-04-05 2022-09-14 3M Innovative Properties Company Gel adhesive comprising crosslinked blend of polydiorganosiloxane and acrylic polymer
AU2019261403A1 (en) * 2018-04-25 2020-11-12 Shinkei Therapeutics, Inc. Tetrabenazine transdermal delivery device
CA3101420A1 (en) 2018-06-20 2019-12-26 Lts Lohmann Therapie-Systeme Ag Transdermal therapeutic system containing asenapine
US20210347978A1 (en) * 2018-09-19 2021-11-11 Isp Investments Llc Peroxide stable polymer composition and process for its preparation and applications thereof
US20210346662A1 (en) 2018-10-23 2021-11-11 Kindeva Drug Delivery L.P. Tamper evident transdermal patch
KR102054346B1 (ko) * 2019-06-20 2019-12-10 한국지질자원연구원 알파 교감신경 차단제 화합물 및 점토광물의 복합체를 포함하는 방출성이 제어된 경구투여용 조성물
DE102019120403A1 (de) * 2019-07-29 2021-02-04 Lts Lohmann Therapie-Systeme Ag Verfahren zur Herstellung von Haftklebemassen zur Verwendung in einem transdermalen therapeutischen System
US11389409B2 (en) 2019-08-30 2022-07-19 Remedy Diagnostics LLC Transdermal device comprising acetaminophen prodrug
CN110693857B (zh) * 2019-10-17 2023-08-11 宜昌人福药业有限责任公司 一种舒芬太尼透皮贴剂及其制备方法
RU2736081C1 (ru) * 2019-12-02 2020-11-11 федеральное государственное бюджетное образовательное учреждение высшего образования "Волгоградский государственный медицинский университет" Министерства здравоохранения Российской Федерации Пластырь трансдермальный с гликлазидом
US11633405B2 (en) 2020-02-07 2023-04-25 Therapeuticsmd, Inc. Steroid hormone pharmaceutical formulations

Family Cites Families (54)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE786957A (fr) * 1968-08-01 1973-01-29 Raychem Corp Compositions de polymeres.
US3972995A (en) * 1975-04-14 1976-08-03 American Home Products Corporation Dosage form
JPS5489017A (en) * 1977-12-26 1979-07-14 Lion Dentifrice Co Ltd Ointment agent
US4291015A (en) * 1979-08-14 1981-09-22 Key Pharmaceuticals, Inc. Polymeric diffusion matrix containing a vasodilator
US4438139A (en) * 1979-08-14 1984-03-20 Key Pharmaceuticals, Inc. Polymeric diffusion matrix containing estrogens
JPS5843368B2 (ja) * 1980-10-30 1983-09-27 日東電工株式会社 消炎鎮痛貼付剤
US4542013A (en) * 1981-07-08 1985-09-17 Key Pharmaceuticals, Inc. Trinitroglycerol sustained release vehicles and preparation therefrom
GB2105990B (en) * 1981-08-27 1985-06-19 Nitto Electric Ind Co Adhesive skin patches
US4699146A (en) * 1982-02-25 1987-10-13 Valleylab, Inc. Hydrophilic, elastomeric, pressure-sensitive adhesive
US4750482A (en) * 1982-02-25 1988-06-14 Pfizer Inc. Hydrophilic, elastomeric, pressure-sensitive adhesive
JPS58225010A (ja) * 1982-06-25 1983-12-27 Dai Ichi Seiyaku Co Ltd コルチコステロイド類外用製剤
US4769013A (en) * 1982-09-13 1988-09-06 Hydromer, Inc. Bio-effecting medical material and device
US4585452A (en) * 1983-04-12 1986-04-29 Key Pharmaceuticals, Inc. Transdermal systemic dosage forms
US4693887A (en) * 1983-09-15 1987-09-15 The Kendall Company Microphase separated hydrogels for controlled release of bioactive materials
US4696821A (en) * 1983-10-11 1987-09-29 Warner-Lambert Company Transdermal delivery system for administration of nitroglycerin
GB8629639D0 (en) * 1986-12-11 1987-01-21 Beecham Group Plc Composition & method
US4845081A (en) * 1984-10-18 1989-07-04 University Of Florida Aminomethyl derivatives of biologically active substances, and enhanced delivery thereof across topical membranes
US4593053A (en) * 1984-12-07 1986-06-03 Medtronic, Inc. Hydrophilic pressure sensitive biomedical adhesive composition
ATE95430T1 (de) * 1984-12-22 1993-10-15 Sanol Arznei Schwarz Gmbh Wirkstoffpflaster.
US4883669A (en) * 1985-02-25 1989-11-28 Rutgers, The State University Of New Jersey Transdermal absorption dosage unit for estradiol and other estrogenic steroids and process for administration
DE3517080A1 (de) * 1985-05-11 1986-11-13 Bayer Ag, 5090 Leverkusen Komponente fuer therapeutische wirkstoffabgabesysteme
GB8512358D0 (en) * 1985-05-16 1985-06-19 Euro Celtique Sa Transdermal delivery system
US4690683A (en) * 1985-07-02 1987-09-01 Rutgers, The State University Of New Jersey Transdermal varapamil delivery device
EP0243891B1 (en) * 1986-04-29 1991-08-14 Hoechst-Roussel Pharmaceuticals Incorporated A laminar structure for administering a chemical at a controlled release rate
ES2028074T3 (es) * 1986-06-13 1992-07-01 Alza Corporation Activacion por humedad de un sistema de suministro transdermico de farmacos.
AU607172B2 (en) * 1986-12-22 1991-02-28 Cygnus, Inc. Diffusion matrix for transdermal drug administration
US4906169A (en) * 1986-12-29 1990-03-06 Rutgers, The State University Of New Jersey Transdermal estrogen/progestin dosage unit, system and process
US5071656A (en) * 1987-03-05 1991-12-10 Alza Corporation Delayed onset transdermal delivery device
IL86211A (en) * 1987-05-04 1992-03-29 Ciba Geigy Ag Oral forms of administration for carbamazepine in the forms of stable aqueous suspension with delayed release and their preparation
US5059189A (en) * 1987-09-08 1991-10-22 E. R. Squibb & Sons, Inc. Method of preparing adhesive dressings containing a pharmaceutically active ingredient
US5474783A (en) * 1988-03-04 1995-12-12 Noven Pharmaceuticals, Inc. Solubility parameter based drug delivery system and method for altering drug saturation concentration
US4814168A (en) * 1988-03-04 1989-03-21 Noven Pharmaceuticals, Inc. Transdermal multipolymer drug delivery system
US4994267A (en) * 1988-03-04 1991-02-19 Noven Pharmaceuticals, Inc. Transdermal acrylic multipolymer drug delivery system
EP0343807A3 (en) * 1988-05-27 1991-01-02 SMITH & NEPHEW UNITED, INC. Absorptive adhesive dressing with controlled hydration
DE58906975D1 (de) * 1988-08-02 1994-03-24 Ciba Geigy Mehrschichtiges Pflaster.
US4987893A (en) * 1988-10-12 1991-01-29 Rochal Industries, Inc. Conformable bandage and coating material
ZA899112B (en) * 1988-12-01 1990-08-29 Schering Corp Compositions for transdermal delivery of estradiol
DE3910543A1 (de) * 1989-04-01 1990-10-11 Lohmann Therapie Syst Lts Transdermales therapeutisches system mit erhoehtem wirkstofffluss und verfahren zu seiner herstellung
US5232703A (en) * 1989-07-21 1993-08-03 Izhak Blank Estradiol compositions and methods for topical application
EP0409383B1 (en) * 1989-07-21 1994-04-06 Izhak Blank Estradiol compositions and methods for topical applications
US5262165A (en) * 1992-02-04 1993-11-16 Schering Corporation Transdermal nitroglycerin patch with penetration enhancers
US5252334A (en) * 1989-09-08 1993-10-12 Cygnus Therapeutic Systems Solid matrix system for transdermal drug delivery
CA2065311C (en) * 1989-09-08 2000-01-11 Chia-Ming Chiang Solid matrix system for transdermal drug delivery
DE3933460A1 (de) * 1989-10-06 1991-04-18 Lohmann Therapie Syst Lts Oestrogenhaltiges wirkstoffpflaster
US5230896A (en) * 1989-10-12 1993-07-27 Warner-Lambert Company Transdermal nicotine delivery system
AU6712090A (en) * 1989-10-13 1991-05-16 Watson Laboratories, Inc. Drug delivery systems and matrix therefor
JP2820306B2 (ja) * 1990-02-27 1998-11-05 積水化学工業株式会社 経皮吸収製剤
JPH07116032B2 (ja) * 1990-04-06 1995-12-13 積水化学工業株式会社 ニトログリセリン貼付剤
IT1243745B (it) * 1990-10-17 1994-06-21 Vectorpharma Int Composizioni terapeutiche transdermali contenenti farmaco e/o agente promotore dell'assorbimento cutaneo supportato su particelle microporose e microsfere polimeriche e loro preparazione.
US5232702A (en) * 1991-07-22 1993-08-03 Dow Corning Corporation Silicone pressure sensitive adhesive compositons for transdermal drug delivery devices and related medical devices
US5203768A (en) * 1991-07-24 1993-04-20 Alza Corporation Transdermal delivery device
DE4210711A1 (de) * 1991-10-31 1993-05-06 Schering Ag Berlin Und Bergkamen, 1000 Berlin, De Transdermale therapeutische systeme mit kristallisationsinhibitoren
US5676968A (en) * 1991-10-31 1997-10-14 Schering Aktiengesellschaft Transdermal therapeutic systems with crystallization inhibitors
FR2739031B1 (fr) * 1995-09-27 1997-11-21 Lhd Lab Hygiene Dietetique Systeme matriciel transdermique d'administration d'un oestrogene et/ou d'un progestatif a base de copolymere styrene-isoprene-styrene, procede de preparation et utilisation en therapeutique

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US6024976A (en) 2000-02-15
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US6221383B1 (en) 2001-04-24
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