AR033748A1 - Un dispositivo para la administracion transdermica de sustancias farmacologicamente activas que comprende dos capas adhesivas superpuestas y un procedimiento para prepararlo - Google Patents
Un dispositivo para la administracion transdermica de sustancias farmacologicamente activas que comprende dos capas adhesivas superpuestas y un procedimiento para prepararloInfo
- Publication number
- AR033748A1 AR033748A1 ARP020101791A ARP020101791A AR033748A1 AR 033748 A1 AR033748 A1 AR 033748A1 AR P020101791 A ARP020101791 A AR P020101791A AR P020101791 A ARP020101791 A AR P020101791A AR 033748 A1 AR033748 A1 AR 033748A1
- Authority
- AR
- Argentina
- Prior art keywords
- active substances
- procedure
- transdermal administration
- pharmacologically active
- prepare
- Prior art date
Links
- 239000013543 active substance Substances 0.000 title abstract 4
- 239000012790 adhesive layer Substances 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- 239000010410 layer Substances 0.000 abstract 3
- 239000004820 Pressure-sensitive adhesive Substances 0.000 abstract 2
- 239000000853 adhesive Substances 0.000 abstract 2
- 230000001070 adhesive effect Effects 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 238000004519 manufacturing process Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7092—Transdermal patches having multiple drug layers or reservoirs, e.g. for obtaining a specific release pattern, or for combining different drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4468—Non condensed piperidines, e.g. piperocaine having a nitrogen directly attached in position 4, e.g. clebopride, fentanyl
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
- A61K9/7061—Polyacrylates
Abstract
Un dispositivo para la administración transdérmica de sustancias farmacológicamente activas que comprende dos capas adhesivas superpuesta en el cual la primera capa está compuesta por un adhesivo sensible a la presión y la segunda capa está compuesta por un adhesivo o por una mezcla de adhesivos sensibles a la presión y en las cuales una o más sustancias activas se encuentran disueltas, porque cada una de las capas presenta una composición adhesiva diferentes y una afinidad diferente por la o las sustancias activas y porque cada capa adhesiva posee un grado de saturación similar y menor al 100%. Un procedimiento para la manufactura de dicho dispositivo.
Priority Applications (11)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ARP020101791A AR033748A1 (es) | 2002-05-15 | 2002-05-15 | Un dispositivo para la administracion transdermica de sustancias farmacologicamente activas que comprende dos capas adhesivas superpuestas y un procedimiento para prepararlo |
AU2003230032A AU2003230032A1 (en) | 2002-05-15 | 2003-05-15 | Transdermal delivery system with two superimposed adhesive layers having different affinities to the active substance comprised |
MXPA04011214A MXPA04011214A (es) | 2002-05-15 | 2003-05-15 | Sistema de adminsitracion transdermica con dos capas adhesivas superpuestas que tienen afinidades diferentes por la sustancia activa incluida. |
PCT/GB2003/002118 WO2003097020A1 (en) | 2002-05-15 | 2003-05-15 | Transdermal delivery system with two superimposed adhesive layers having different affinities to the active substance comprised |
PCT/GB2003/002120 WO2003097008A2 (en) | 2002-05-15 | 2003-05-15 | Transdermal delivery device for the administration of fentanyl |
AT03722872T ATE352294T1 (de) | 2002-05-15 | 2003-05-15 | Transdermales therapeutisches system mit zwei übereinanderliegenden matrixschichten, die verschiedene affinitäten zum enthaltenen wirkstoff ausweisen |
ES03722872T ES2281641T3 (es) | 2002-05-15 | 2003-05-15 | Sistema de administracion transdermica con dos capas adhesivas superpuestas que tienen diferente afinidad por la sustancia activa. |
US10/514,047 US8017146B2 (en) | 2002-05-15 | 2003-05-15 | Transdermal delivery system with two superimposed adhesive layers having different affinities to the active substance comprised |
AU2003230034A AU2003230034A1 (en) | 2002-05-15 | 2003-05-15 | Transdermal delivery device for the administration of fentanyl |
EP03722872A EP1503743B1 (en) | 2002-05-15 | 2003-05-15 | Transdermal delivery system with two superimposed adhesive layers having different affinities to the active substance comprised |
DE60311449T DE60311449T2 (de) | 2002-05-15 | 2003-05-15 | Transdermales therapeutisches system mit zwei übereinanderliegenden matrixschichten, die verschiedene affinitäten zum enthaltenen wirkstoff ausweisen |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ARP020101791A AR033748A1 (es) | 2002-05-15 | 2002-05-15 | Un dispositivo para la administracion transdermica de sustancias farmacologicamente activas que comprende dos capas adhesivas superpuestas y un procedimiento para prepararlo |
Publications (1)
Publication Number | Publication Date |
---|---|
AR033748A1 true AR033748A1 (es) | 2004-01-07 |
Family
ID=38561712
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP020101791A AR033748A1 (es) | 2002-05-15 | 2002-05-15 | Un dispositivo para la administracion transdermica de sustancias farmacologicamente activas que comprende dos capas adhesivas superpuestas y un procedimiento para prepararlo |
Country Status (9)
Country | Link |
---|---|
US (1) | US8017146B2 (es) |
EP (1) | EP1503743B1 (es) |
AR (1) | AR033748A1 (es) |
AT (1) | ATE352294T1 (es) |
AU (1) | AU2003230032A1 (es) |
DE (1) | DE60311449T2 (es) |
ES (1) | ES2281641T3 (es) |
MX (1) | MXPA04011214A (es) |
WO (1) | WO2003097020A1 (es) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE102004009903A1 (de) | 2004-02-26 | 2005-09-22 | Grünenthal GmbH | Pflaster mit reduzierter Hautirritation |
US9205062B2 (en) | 2004-03-09 | 2015-12-08 | Mylan Pharmaceuticals, Inc. | Transdermal systems containing multilayer adhesive matrices to modify drug delivery |
US20050202073A1 (en) † | 2004-03-09 | 2005-09-15 | Mylan Technologies, Inc. | Transdermal systems containing multilayer adhesive matrices to modify drug delivery |
WO2007095147A2 (en) * | 2006-02-13 | 2007-08-23 | Aveva Drug Delivery Systems | Adhesive preparation comprising sufentanil and methods of using the same |
DE102006054733A1 (de) | 2006-11-21 | 2008-05-29 | Lts Lohmann Therapie-Systeme Ag | Transdermales therapeutisches Systems mit hoher Wirkstoffausnutzungsrate und Dosiergenauigkeit |
WO2008083034A1 (en) * | 2006-12-27 | 2008-07-10 | Nexagen Usa, Llc | Transdermal vitamin b12 delivery patch |
WO2008093772A1 (ja) * | 2007-01-31 | 2008-08-07 | Hisamitsu Pharmaceutical Co., Inc. | 経皮または経粘膜投与のためのアジュバントおよびこれを含む医薬製剤 |
CN104398496B (zh) * | 2007-10-15 | 2018-03-20 | 阿尔扎公司 | 芬太尼的一天更换一次透皮施用 |
US20100087768A1 (en) * | 2008-10-02 | 2010-04-08 | Forlano Paula | Transdermal drug delivery system for liquid active ingredient |
US8952038B2 (en) | 2010-03-26 | 2015-02-10 | Philip Morris Usa Inc. | Inhibition of undesired sensory effects by the compound camphor |
PL2552245T3 (pl) | 2010-03-26 | 2019-05-31 | Philip Morris Products Sa | Inhibicja podrażnienia sensorycznego podczas konsumpcji produktów tytoniowych niepalnych |
US8481560B2 (en) * | 2010-04-02 | 2013-07-09 | Alltranz Inc. | Abuse deterrent transdermal formulations of opiate agonists and agonist-antagonists |
US9546219B2 (en) | 2012-02-08 | 2017-01-17 | North Carolina State University | Treatment of allergic diseases with recombinant antibodies |
AR095259A1 (es) * | 2013-03-15 | 2015-09-30 | Noven Pharma | Composiciones y métodos para la administración transdérmica de fármacos de amina terciaria |
JP6188933B2 (ja) | 2013-10-07 | 2017-08-30 | テイコク ファーマ ユーエスエー インコーポレーテッド | 非鎮静量のデクスメデトミジンの経皮送達用方法及び組成物 |
WO2015054058A1 (en) * | 2013-10-07 | 2015-04-16 | Teikoku Pharma Usa, Inc. | Dexmedetomidine Transdermal Delivery Devices and Methods for Using the Same |
JP6310070B2 (ja) | 2013-10-07 | 2018-04-11 | テイコク ファーマ ユーエスエー インコーポレーテッド | デクスメデトミジン経皮組成物を用いる、注意欠陥多動性障害、不安症及び不眠症の治療法及び組成物 |
JP6940407B2 (ja) * | 2014-12-19 | 2021-09-29 | キンデーバ ドラッグ デリバリー リミティド パートナーシップ | フェンタニルを含む経皮薬物送達デバイス |
WO2018089335A1 (en) | 2016-11-09 | 2018-05-17 | North Carolina State University | Treatment of allergic diseases with chimeric protein |
KR20220163495A (ko) * | 2017-06-08 | 2022-12-09 | 애프리컷 지엠비에이치 | 피부 관리 및 피부 노화 방지를 위한 활성 물질이 포함된 실리콘 패드 |
Family Cites Families (27)
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US4262003A (en) | 1975-12-08 | 1981-04-14 | Alza Corporation | Method and therapeutic system for administering scopolamine transdermally |
US4031894A (en) | 1975-12-08 | 1977-06-28 | Alza Corporation | Bandage for transdermally administering scopolamine to prevent nausea |
US4436741A (en) | 1975-12-08 | 1984-03-13 | Alza Corporation | Method for administering scopolamine transdermally |
US4060084A (en) | 1976-09-07 | 1977-11-29 | Alza Corporation | Method and therapeutic system for providing chemotherapy transdermally |
US4201211A (en) | 1977-07-12 | 1980-05-06 | Alza Corporation | Therapeutic system for administering clonidine transdermally |
US4286592A (en) | 1980-02-04 | 1981-09-01 | Alza Corporation | Therapeutic system for administering drugs to the skin |
US5310559A (en) | 1982-09-01 | 1994-05-10 | Hercon Laboratories Corporation | Device for controlled release and delivery to mammalian tissue of pharmacologically active agents incorporating a rate controlling member which comprises an alkylene-alkyl acrylate copolymer |
DE3315272C2 (de) | 1983-04-27 | 1986-03-27 | Lohmann Gmbh & Co Kg, 5450 Neuwied | Pharmazeutisches Produkt und Verfahren zu seiner Herstellung |
US4938759A (en) | 1986-09-02 | 1990-07-03 | Alza Corporation | Transdermal delivery device having a rate controlling adhesive |
US4906463A (en) | 1986-12-22 | 1990-03-06 | Cygnus Research Corporation | Transdermal drug-delivery composition |
US5006342A (en) | 1986-12-22 | 1991-04-09 | Cygnus Corporation | Resilient transdermal drug delivery device |
US5474783A (en) | 1988-03-04 | 1995-12-12 | Noven Pharmaceuticals, Inc. | Solubility parameter based drug delivery system and method for altering drug saturation concentration |
US5656286A (en) | 1988-03-04 | 1997-08-12 | Noven Pharmaceuticals, Inc. | Solubility parameter based drug delivery system and method for altering drug saturation concentration |
US5004610A (en) | 1988-06-14 | 1991-04-02 | Alza Corporation | Subsaturated nicotine transdermal therapeutic system |
DE3908432A1 (de) * | 1989-03-14 | 1990-09-27 | Lohmann Therapie Syst Lts | Pflaster als therapeutisches system zur verabreichung von wirkstoffen an die haut mit einer abgestuften wirkstoffabgabe, verfahren zu seiner herstellung sowie verwendung |
DE3910543A1 (de) * | 1989-04-01 | 1990-10-11 | Lohmann Therapie Syst Lts | Transdermales therapeutisches system mit erhoehtem wirkstofffluss und verfahren zu seiner herstellung |
CA2075517C (en) * | 1992-04-01 | 1997-03-11 | John Wick | Transdermal patch incorporating a polymer film incorporated with an active agent |
DE4223360C1 (es) * | 1992-07-16 | 1993-04-08 | Lts Lohmann Therapie-Systeme Gmbh & Co Kg, 5450 Neuwied, De | |
DE4310012A1 (de) * | 1993-03-27 | 1994-09-29 | Roehm Gmbh | Dermales therapeutisches System aus einer schmelzfähigen Poly(meth)acrylat-Mischung |
US5494680A (en) * | 1993-12-08 | 1996-02-27 | Minnesota Mining And Manufacturing Company | Transdermal delivery device |
DE19527925C2 (de) | 1995-07-29 | 1997-07-03 | Lohmann Therapie Syst Lts | Transdermales therapeutisches System mit einer trennmittelbeschichteten Schutzschicht |
US6174545B1 (en) | 1997-07-01 | 2001-01-16 | Alza Corporation | Drug delivery devices and process of manufacture |
CA2331264C (en) | 1999-01-14 | 2008-09-23 | Noven Pharmaceuticals, Inc. | Compositions and methods for drug delivery |
KR20010036685A (ko) * | 1999-10-11 | 2001-05-07 | 김윤 | 펜타닐을 함유하는 매트릭스형 경피투여제 |
FR2801507B1 (fr) | 1999-11-30 | 2003-06-27 | Pf Medicament | Dispositif transdermique auto-adhesif comprenant un reservoir et une matrice contenant le meme principe actif, son procede de preparation et ses utilisations |
US20020119187A1 (en) | 2000-09-29 | 2002-08-29 | Cantor Adam S. | Composition for the transdermal delivery of fentanyl |
AU2003268376A1 (en) | 2002-08-30 | 2004-11-26 | Watson Pharmaceuticals, Inc. | Transdermal delivery systems and methods |
-
2002
- 2002-05-15 AR ARP020101791A patent/AR033748A1/es unknown
-
2003
- 2003-05-15 AU AU2003230032A patent/AU2003230032A1/en not_active Abandoned
- 2003-05-15 MX MXPA04011214A patent/MXPA04011214A/es active IP Right Grant
- 2003-05-15 US US10/514,047 patent/US8017146B2/en not_active Expired - Fee Related
- 2003-05-15 ES ES03722872T patent/ES2281641T3/es not_active Expired - Lifetime
- 2003-05-15 WO PCT/GB2003/002118 patent/WO2003097020A1/en active IP Right Grant
- 2003-05-15 EP EP03722872A patent/EP1503743B1/en not_active Expired - Lifetime
- 2003-05-15 AT AT03722872T patent/ATE352294T1/de not_active IP Right Cessation
- 2003-05-15 DE DE60311449T patent/DE60311449T2/de not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
EP1503743A1 (en) | 2005-02-09 |
DE60311449T2 (de) | 2007-11-08 |
AU2003230032A1 (en) | 2003-12-02 |
ES2281641T3 (es) | 2007-10-01 |
DE60311449D1 (de) | 2007-03-15 |
ATE352294T1 (de) | 2007-02-15 |
US8017146B2 (en) | 2011-09-13 |
WO2003097020A1 (en) | 2003-11-27 |
US20050208116A1 (en) | 2005-09-22 |
EP1503743B1 (en) | 2007-01-24 |
MXPA04011214A (es) | 2005-11-04 |
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Legal Events
Date | Code | Title | Description |
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FB | Suspension of granting procedure |