HUP0303719A2 - Mitoxantron hatóanyag-tartalmú liposzómás gyógyszerkészítmények és eljárás az előállításukra - Google Patents

Mitoxantron hatóanyag-tartalmú liposzómás gyógyszerkészítmények és eljárás az előállításukra

Info

Publication number
HUP0303719A2
HUP0303719A2 HU0303719A HUP0303719A HUP0303719A2 HU P0303719 A2 HUP0303719 A2 HU P0303719A2 HU 0303719 A HU0303719 A HU 0303719A HU P0303719 A HUP0303719 A HU P0303719A HU P0303719 A2 HUP0303719 A2 HU P0303719A2
Authority
HU
Hungary
Prior art keywords
mitoxantrone
liposomal
pharmaceutical composition
amitoxantrone
preparation
Prior art date
Application number
HU0303719A
Other languages
English (en)
Inventor
Imran Ahmad
Aquilur Rahman
Original Assignee
Neopharm, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neopharm, Inc. filed Critical Neopharm, Inc.
Publication of HUP0303719A2 publication Critical patent/HUP0303719A2/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/136—Amines having aromatic rings, e.g. ketamine, nortriptyline having the amino group directly attached to the aromatic ring, e.g. benzeneamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Abstract

Jelen találmány mitoxantron hatóanyag-tartalmú liposzómásgyógyszerkészítményekre, ezek előállítási eljárásaira és alkalmazásáravonatkozik. A jelen találmány szerinti gyógyszerkészítmények amitoxantron liposzómás összetételeit tartalmazzák, amelyekben aliposzóma a különféle semleges vagy töltéssel rendelkezőliposzómaképző vegyületekkel együtt egy olyan anyagot tartalmaz,amelyről ismert, hogy megköti a mitoxantront. Ilyen anyag például akardiolipin. A liposzómás készítmények előnyösen alkalmazhatók amitoxantrontól különböző másodlagos terápiás szerekkel együtt, példáulantineoplazmás, gombaellenes szerekkel, antibiotikumokkal stb. Atalálmány a gyógyszerkészítmény-összetétel terápiásan hatékonymennyiségének adagolásából álló eljárásokra is vonatkozik. Ó
HU0303719A 2000-10-16 2001-10-16 Mitoxantron hatóanyag-tartalmú liposzómás gyógyszerkészítmények és eljárás az előállításukra HUP0303719A2 (hu)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US24106900P 2000-10-16 2000-10-16
PCT/US2001/042757 WO2002032400A1 (en) 2000-10-16 2001-10-16 Liposomal formulation of mitoxantrone

Publications (1)

Publication Number Publication Date
HUP0303719A2 true HUP0303719A2 (hu) 2004-03-01

Family

ID=22909113

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0303719A HUP0303719A2 (hu) 2000-10-16 2001-10-16 Mitoxantron hatóanyag-tartalmú liposzómás gyógyszerkészítmények és eljárás az előállításukra

Country Status (15)

Country Link
US (1) US20030219476A1 (hu)
EP (1) EP1333811A4 (hu)
JP (1) JP2004511510A (hu)
CN (1) CN1469735A (hu)
AU (1) AU2002214649A1 (hu)
BR (1) BR0114713A (hu)
CA (1) CA2424345A1 (hu)
CZ (1) CZ20031262A3 (hu)
EA (1) EA200300473A1 (hu)
HU (1) HUP0303719A2 (hu)
IL (1) IL155291A0 (hu)
MX (1) MXPA03003401A (hu)
NO (1) NO20031623L (hu)
WO (1) WO2002032400A1 (hu)
ZA (1) ZA200302670B (hu)

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Also Published As

Publication number Publication date
CZ20031262A3 (en) 2004-03-17
ZA200302670B (en) 2004-07-05
IL155291A0 (en) 2003-11-23
MXPA03003401A (es) 2004-06-30
CA2424345A1 (en) 2002-04-25
NO20031623D0 (no) 2003-04-09
AU2002214649A1 (en) 2002-04-29
EP1333811A4 (en) 2004-03-03
EP1333811A1 (en) 2003-08-13
WO2002032400A1 (en) 2002-04-25
US20030219476A1 (en) 2003-11-27
NO20031623L (no) 2003-06-05
CN1469735A (zh) 2004-01-21
BR0114713A (pt) 2004-01-13
EA200300473A1 (ru) 2003-08-28
JP2004511510A (ja) 2004-04-15

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