BR9907270A - Composto, composição farmacêutica, uso de um composto, e, processos para tratamento ou profilaxia de doenças inflamatórias, por exemplo, asma ou copd, e para a preparação de um composto - Google Patents
Composto, composição farmacêutica, uso de um composto, e, processos para tratamento ou profilaxia de doenças inflamatórias, por exemplo, asma ou copd, e para a preparação de um compostoInfo
- Publication number
- BR9907270A BR9907270A BR9907270-0A BR9907270A BR9907270A BR 9907270 A BR9907270 A BR 9907270A BR 9907270 A BR9907270 A BR 9907270A BR 9907270 A BR9907270 A BR 9907270A
- Authority
- BR
- Brazil
- Prior art keywords
- compound
- processes
- treatment
- inflammatory diseases
- copd
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H1/00—Processes for the preparation of sugar derivatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
Abstract
"COMPOSTO, COMPOSIçãO FARMACêUTICA, USO DE UM COMPOSTO, E, PROCESSOS PARA TRATAMENTO OU PROFILAXIA DE DOENçAS INFLAMATóRIAS, POR EXEMPLO, ASMA OU COPD, E PARA A PREPARAçãO DE UM COMPOSTO" São fornecidos de acordo, com a invenção, novos compostos da fórmula (I) em que R^ 1^, R^ 2^ e R^ 3^ são como descritos no relatório descritivo, processos para prepará-los, formulações que os contenham e seu uso em terapia para o tratamento de doenças inflamatórias.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9802066.2A GB9802066D0 (en) | 1998-01-31 | 1998-01-31 | Chemical compounds |
GBGB9813528.8A GB9813528D0 (en) | 1998-06-23 | 1998-06-23 | Chemical compounds |
PCT/EP1999/000503 WO1999038877A2 (en) | 1998-01-31 | 1999-01-29 | 2-(PURIN-9-yl)-TETRAHYDROFURAN-3,4-DIOL DERIVATIVES |
Publications (1)
Publication Number | Publication Date |
---|---|
BR9907270A true BR9907270A (pt) | 2000-10-24 |
Family
ID=26313042
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR9907270-0A BR9907270A (pt) | 1998-01-31 | 1999-01-29 | Composto, composição farmacêutica, uso de um composto, e, processos para tratamento ou profilaxia de doenças inflamatórias, por exemplo, asma ou copd, e para a preparação de um composto |
Country Status (39)
Country | Link |
---|---|
US (1) | US6762170B1 (pt) |
EP (1) | EP1051425B1 (pt) |
JP (1) | JP2002501928A (pt) |
KR (1) | KR20010034473A (pt) |
CN (1) | CN1289338A (pt) |
AP (1) | AP2000001875A0 (pt) |
AR (1) | AR014508A1 (pt) |
AT (1) | ATE226957T1 (pt) |
AU (1) | AU757183B2 (pt) |
BG (1) | BG63783B1 (pt) |
BR (1) | BR9907270A (pt) |
CA (1) | CA2318278A1 (pt) |
CO (1) | CO4980872A1 (pt) |
DE (1) | DE69903708T2 (pt) |
DK (1) | DK1051425T3 (pt) |
EA (1) | EA003194B1 (pt) |
EE (1) | EE200000441A (pt) |
ES (1) | ES2186330T3 (pt) |
GE (1) | GEP20022839B (pt) |
HK (1) | HK1030611A1 (pt) |
HR (1) | HRP20000511A2 (pt) |
HU (1) | HUP0101305A3 (pt) |
ID (1) | ID26326A (pt) |
IL (1) | IL137042A0 (pt) |
IS (1) | IS5550A (pt) |
MA (1) | MA26601A1 (pt) |
NO (1) | NO20003867L (pt) |
NZ (1) | NZ505452A (pt) |
OA (1) | OA11447A (pt) |
PE (1) | PE20000280A1 (pt) |
PL (1) | PL342670A1 (pt) |
PT (1) | PT1051425E (pt) |
SI (1) | SI1051425T1 (pt) |
SK (1) | SK11192000A3 (pt) |
SV (1) | SV1999000009A (pt) |
TR (1) | TR200002218T2 (pt) |
TW (1) | TW434250B (pt) |
WO (1) | WO1999038877A2 (pt) |
YU (1) | YU44900A (pt) |
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US6232297B1 (en) | 1999-02-01 | 2001-05-15 | University Of Virginia Patent Foundation | Methods and compositions for treating inflammatory response |
US7427606B2 (en) | 1999-02-01 | 2008-09-23 | University Of Virginia Patent Foundation | Method to reduce inflammatory response in transplanted tissue |
US7378400B2 (en) | 1999-02-01 | 2008-05-27 | University Of Virginia Patent Foundation | Method to reduce an inflammatory response from arthritis |
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US20040162422A1 (en) * | 2001-03-20 | 2004-08-19 | Adrian Hall | Chemical compounds |
WO2003029264A2 (en) | 2001-10-01 | 2003-04-10 | University Of Virginia Patent Foundation | 2-propynyl adenosine analogs having a2a agonist activity and compositions thereof |
GB0206657D0 (en) * | 2002-03-21 | 2002-05-01 | Glaxo Group Ltd | Novel intermediate and process |
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AR044519A1 (es) | 2003-05-02 | 2005-09-14 | Novartis Ag | Derivados de piridin-tiazol amina y de pirimidin-tiazol amina |
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GB0401334D0 (en) | 2004-01-21 | 2004-02-25 | Novartis Ag | Organic compounds |
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US7442687B2 (en) | 2004-08-02 | 2008-10-28 | The University Of Virginia Patent Foundation | 2-polycyclic propynyl adenosine analogs having A2A agonist activity |
AU2005267706B2 (en) | 2004-08-02 | 2011-12-08 | University Of Virginia Patent Foundation | 2-propynyl adenosine analogs with modified 5'-ribose groups having A2A agonist activity |
US7576069B2 (en) | 2004-08-02 | 2009-08-18 | University Of Virginia Patent Foundation | 2-polycyclic propynyl adenosine analogs having A2A agonist activity |
GB0424284D0 (en) | 2004-11-02 | 2004-12-01 | Novartis Ag | Organic compounds |
GB0426164D0 (en) | 2004-11-29 | 2004-12-29 | Novartis Ag | Organic compounds |
GB0510390D0 (en) | 2005-05-20 | 2005-06-29 | Novartis Ag | Organic compounds |
GB0514809D0 (en) | 2005-07-19 | 2005-08-24 | Glaxo Group Ltd | Compounds |
CA2625664C (en) | 2005-10-21 | 2016-01-05 | Novartis Ag | Human antibodies against il13 and therapeutic uses |
GB0601951D0 (en) | 2006-01-31 | 2006-03-15 | Novartis Ag | Organic compounds |
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TW528755B (en) | 1996-12-24 | 2003-04-21 | Glaxo Group Ltd | 2-(purin-9-yl)-tetrahydrofuran-3,4-diol derivatives |
YU44900A (sh) | 1998-01-31 | 2003-01-31 | Glaxo Group Limited | Derivati 2-(purin-9-il)tetrahidrofuran-3,4-diola |
CO4990969A1 (es) * | 1998-02-14 | 2000-12-26 | Glaxo Group Ltd | Derivados de 2-(purin-9-il)-tetrahidrofuran-3,4-diol |
ATE246701T1 (de) | 1998-06-23 | 2003-08-15 | Glaxo Group Ltd | 2-(purin-9-yl)-tetrahydrofuran-3,4-diol derivate |
GB9813535D0 (en) | 1998-06-23 | 1998-08-19 | Glaxo Group Ltd | Chemical compounds |
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1998
- 1998-01-31 YU YU44900A patent/YU44900A/sh unknown
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1999
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- 1999-01-29 CN CN99802548A patent/CN1289338A/zh active Pending
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- 1999-01-29 ES ES99907427T patent/ES2186330T3/es not_active Expired - Lifetime
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- 1999-01-29 JP JP2000529344A patent/JP2002501928A/ja active Pending
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2000
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