DE69123974T2 - Verbindungen welche antihypertensive und antiischemische eigenschaften besitzen - Google Patents

Verbindungen welche antihypertensive und antiischemische eigenschaften besitzen

Info

Publication number
DE69123974T2
DE69123974T2 DE69123974T DE69123974T DE69123974T2 DE 69123974 T2 DE69123974 T2 DE 69123974T2 DE 69123974 T DE69123974 T DE 69123974T DE 69123974 T DE69123974 T DE 69123974T DE 69123974 T2 DE69123974 T2 DE 69123974T2
Authority
DE
Germany
Prior art keywords
hypertensive
connections
chemical properties
compounds
adenosine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69123974T
Other languages
English (en)
Other versions
DE69123974D1 (de
Inventor
Alfred P Spada
Cynthia A Fink
Michael Myers
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rhone Poulenc Rorer International Holdings Inc
Original Assignee
Rhone Poulenc Rorer International Holdings Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer International Holdings Inc filed Critical Rhone Poulenc Rorer International Holdings Inc
Publication of DE69123974D1 publication Critical patent/DE69123974D1/de
Application granted granted Critical
Publication of DE69123974T2 publication Critical patent/DE69123974T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/052—Imidazole radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
DE69123974T 1990-09-25 1991-09-25 Verbindungen welche antihypertensive und antiischemische eigenschaften besitzen Expired - Fee Related DE69123974T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US58788490A 1990-09-25 1990-09-25
PCT/US1991/006990 WO1992005177A1 (en) 1990-09-25 1991-09-25 Compounds having antihypertensive and anti-ischemic properties

Publications (2)

Publication Number Publication Date
DE69123974D1 DE69123974D1 (de) 1997-02-13
DE69123974T2 true DE69123974T2 (de) 1997-05-07

Family

ID=24351576

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69123974T Expired - Fee Related DE69123974T2 (de) 1990-09-25 1991-09-25 Verbindungen welche antihypertensive und antiischemische eigenschaften besitzen

Country Status (14)

Country Link
US (1) US5364862A (de)
EP (1) EP0550631B1 (de)
JP (1) JP2505085B2 (de)
AT (1) ATE147074T1 (de)
AU (1) AU654507B2 (de)
CA (1) CA2092305C (de)
DE (1) DE69123974T2 (de)
DK (1) DK0550631T3 (de)
ES (1) ES2095960T3 (de)
GR (1) GR3022207T3 (de)
HK (1) HK1002031A1 (de)
MX (1) MX9203771A (de)
SG (1) SG80526A1 (de)
WO (1) WO1992005177A1 (de)

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US5364862A (en) 1994-11-15
AU654507B2 (en) 1994-11-10
SG80526A1 (en) 2001-05-22
DE69123974D1 (de) 1997-02-13
MX9203771A (es) 1992-09-01
AU8726691A (en) 1992-04-15
GR3022207T3 (en) 1997-04-30
EP0550631B1 (de) 1997-01-02
WO1992005177A1 (en) 1992-04-02
JPH05508864A (ja) 1993-12-09
JP2505085B2 (ja) 1996-06-05
DK0550631T3 (da) 1997-01-20
CA2092305C (en) 2003-02-11
EP0550631A1 (de) 1993-07-14
EP0550631A4 (en) 1994-08-10
CA2092305A1 (en) 1992-03-26
ES2095960T3 (es) 1997-03-01
ATE147074T1 (de) 1997-01-15
HK1002031A1 (en) 1998-07-24

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