ES2667729T3
(es)
|
2007-09-26 |
2018-05-14 |
Ucb Biopharma Sprl |
Fusiones de anticuerpos con doble especificidad
|
US20090162359A1
(en)
|
2007-12-21 |
2009-06-25 |
Christian Klein |
Bivalent, bispecific antibodies
|
US9266967B2
(en)
|
2007-12-21 |
2016-02-23 |
Hoffmann-La Roche, Inc. |
Bivalent, bispecific antibodies
|
EP2334705B1
(en)
|
2008-09-26 |
2016-12-14 |
UCB Biopharma SPRL |
Biological products
|
WO2010040105A2
(en)
|
2008-10-02 |
2010-04-08 |
Trubion Pharmaceuticals, Inc. |
Cd86 antagonist multi-target binding proteins
|
EP2414391B1
(en)
|
2009-04-02 |
2018-11-28 |
Roche Glycart AG |
Multispecific antibodies comprising full length antibodies and single chain fab fragments
|
WO2010115589A1
(en)
|
2009-04-07 |
2010-10-14 |
Roche Glycart Ag |
Trivalent, bispecific antibodies
|
US9676845B2
(en)
|
2009-06-16 |
2017-06-13 |
Hoffmann-La Roche, Inc. |
Bispecific antigen binding proteins
|
US8703132B2
(en)
|
2009-06-18 |
2014-04-22 |
Hoffmann-La Roche, Inc. |
Bispecific, tetravalent antigen binding proteins
|
JO3182B1
(ar)
*
|
2009-07-29 |
2018-03-08 |
Regeneron Pharma |
مضادات حيوية بشرية عالية الالفة مع تولد الاوعية البشرية - 2
|
RU2573915C2
(ru)
|
2009-09-16 |
2016-01-27 |
Дженентек, Инк. |
Содержащие суперспираль и/или привязку белковые комплексы и их применение
|
EP2519544A1
(en)
*
|
2009-12-29 |
2012-11-07 |
Emergent Product Development Seattle, LLC |
Polypeptide heterodimers and uses thereof
|
GB201000467D0
(en)
*
|
2010-01-12 |
2010-02-24 |
Ucb Pharma Sa |
Antibodies
|
AR080793A1
(es)
|
2010-03-26 |
2012-05-09 |
Roche Glycart Ag |
Anticuerpos biespecificos
|
WO2011147834A1
(en)
|
2010-05-26 |
2011-12-01 |
Roche Glycart Ag |
Antibodies against cd19 and uses thereof
|
KR20130126576A
(ko)
|
2010-07-19 |
2013-11-20 |
에프. 호프만-라 로슈 아게 |
항암요법에 반응할 가능성이 증가된 환자를 확인하는 방법
|
BR112013001431A2
(pt)
|
2010-07-19 |
2016-05-31 |
Hoffmann La Roche |
método de identificação de pacientes com maior probabilidade de reação a terapia anticâncer
|
WO2012010582A1
(en)
|
2010-07-21 |
2012-01-26 |
Roche Glycart Ag |
Anti-cxcr5 antibodies and methods of use
|
EP2600898A1
(en)
|
2010-08-05 |
2013-06-12 |
F.Hoffmann-La Roche Ag |
Anti-mhc antibody anti-viral cytokine fusion protein
|
WO2012025530A1
(en)
|
2010-08-24 |
2012-03-01 |
F. Hoffmann-La Roche Ag |
Bispecific antibodies comprising a disulfide stabilized - fv fragment
|
MX352929B
(es)
|
2010-11-05 |
2017-12-13 |
Zymeworks Inc |
DISEÑO DE ANTICUERPOS HETERODIMÉRICOS ESTABLES CON MUTACIONES EN EL DOMINIO Fc.
|
US11066483B2
(en)
|
2010-11-30 |
2021-07-20 |
Chugai Seiyaku Kabushiki Kaisha |
Cytotoxicity-inducing therapeutic agent
|
WO2012085111A1
(en)
|
2010-12-23 |
2012-06-28 |
F. Hoffmann-La Roche Ag |
Polypeptide-polynucleotide-complex and its use in targeted effector moiety delivery
|
TW201309330A
(zh)
*
|
2011-01-28 |
2013-03-01 |
Abbott Lab |
包含糖基化抗體之組合物及其用途
|
JP5768147B2
(ja)
|
2011-02-28 |
2015-08-26 |
エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft |
一価抗原結合タンパク質
|
KR101638224B1
(ko)
|
2011-02-28 |
2016-07-08 |
에프. 호프만-라 로슈 아게 |
항원 결합 단백질
|
MX336197B
(es)
|
2011-04-19 |
2016-01-11 |
Merrimack Pharmaceuticals Inc |
Anicuerpos anti-igf-1r y anti-erbb3 monoespecificos y biespecificos.
|
JP2014514313A
(ja)
|
2011-04-20 |
2014-06-19 |
ロシュ グリクアート アクチェンゲゼルシャフト |
血液脳関門のpH依存性通過のための方法及び構築物
|
EP2721067B1
(en)
|
2011-06-15 |
2019-07-31 |
F.Hoffmann-La Roche Ag |
Anti-human epo receptor antibodies and methods of use
|
CN110229235A
(zh)
|
2011-06-22 |
2019-09-13 |
霍夫曼-拉罗奇有限公司 |
利用包含mhc i类的复合物通过循环中的病毒特异性细胞毒性t细胞清除靶细胞
|
EP2747781B1
(en)
*
|
2011-08-23 |
2017-11-15 |
Roche Glycart AG |
Bispecific antibodies specific for t-cell activating antigens and a tumor antigen and methods of use
|
US20130078250A1
(en)
*
|
2011-08-23 |
2013-03-28 |
Oliver Ast |
Bispecific t cell activating antigen binding molecules
|
PE20141521A1
(es)
*
|
2011-08-23 |
2014-10-25 |
Roche Glycart Ag |
Moleculas biespecificas de union a antigeno activadoras de celulas t
|
CN103781801B
(zh)
*
|
2011-08-23 |
2018-02-09 |
罗切格利卡特公司 |
包含两个Fab片段的无Fc的抗体及使用方法
|
DK2748202T3
(en)
*
|
2011-08-23 |
2018-09-17 |
Roche Glycart Ag |
BISPECIFIC ANTI-BINDING MOLECULES
|
JP2014530009A
(ja)
|
2011-09-29 |
2014-11-17 |
エーピーオー‐ティー ビー.ヴイ. |
異常細胞を標的とする多重特異性結合分子
|
DK2773671T3
(da)
|
2011-11-04 |
2021-11-15 |
Zymeworks Inc |
Udformning af stabilt heterodimert antistof med mutationer i fc-domænet
|
CA2853917A1
(en)
|
2011-12-19 |
2013-06-27 |
F. Hoffmann-La Roche Ag |
Method for the detection of free binding partner of a multispecific binder
|
SG10201900915WA
(en)
|
2011-12-22 |
2019-03-28 |
Hoffmann La Roche |
Expression vector element combinations, novel production cell generation methods and their use for the recombinant production of polypeptides
|
JP2015503907A
(ja)
|
2011-12-22 |
2015-02-05 |
エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft |
真核細胞のための全長抗体提示システムおよびその使用
|
SI2794878T1
(sl)
|
2011-12-22 |
2020-07-31 |
F. Hoffmann-La Roche Ag |
Organizacija ekspresijskega vektorja, postopki izdelave nove proizvodne celice in njihova uporaba za rekombinantno proizvodnjo polipeptidov
|
SG10201705698PA
(en)
|
2012-01-13 |
2017-08-30 |
Apo-T B V |
Aberrant Cell-Restricted Immunoglobulins Provided With A Toxic Moiety
|
JP2015507193A
(ja)
|
2012-02-01 |
2015-03-05 |
エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft |
多重特異性結合物の結合パートナーを検出するための方法
|
CN104379601B
(zh)
|
2012-02-03 |
2021-04-09 |
霍夫曼-拉罗奇有限公司 |
双特异性抗体分子和抗原-转染的t-细胞以及它们在医药中的用途
|
BR112014019579A2
(pt)
|
2012-02-10 |
2019-10-15 |
Genentech, Inc |
Anticorpo de cadeia única, polinucleotídeo, vetor, célula hospedeira, método de produção de um anticorpo de cadeia única, heteromultímero e método de produção do heteromultímero
|
RU2624128C2
(ru)
|
2012-02-15 |
2017-06-30 |
Ф. Хоффманн-Ля Рош Аг |
Аффинная хроматография с применением fc-рецепторов
|
WO2013134414A1
(en)
*
|
2012-03-06 |
2013-09-12 |
Galaxy Biotech, Llc |
Bispecific antibodies with an fgf2 binding domain
|
WO2013158856A2
(en)
|
2012-04-20 |
2013-10-24 |
Emergent Product Development Seattle, Llc |
Cd3 binding polypeptides
|
EP2855531A1
(en)
|
2012-05-24 |
2015-04-08 |
F. Hoffmann-La Roche AG |
Multispecific antibodies
|
WO2014004586A1
(en)
|
2012-06-25 |
2014-01-03 |
Zymeworks Inc. |
Process and methods for efficient manufacturing of highly pure asymmetric antibodies in mammalian cells
|
BR112014032193A2
(pt)
|
2012-06-27 |
2017-06-27 |
Hoffmann La Roche |
métodos de produção de anticorpos biespecíficos e de determinação de combinação, anticorpo biespecífico, formulação e uso de anticorpo biespecífico
|
CA2871882A1
(en)
|
2012-06-27 |
2014-01-03 |
F. Hoffmann-La Roche Ag |
Method for making antibody fc-region conjugates comprising at least one binding entity that specifically binds to a target and uses thereof
|
ES2600154T3
(es)
|
2012-07-04 |
2017-02-07 |
F. Hoffmann-La Roche Ag |
Anticuerpos antiteofilina y métodos de uso
|
CN104411725B
(zh)
|
2012-07-04 |
2018-09-28 |
弗·哈夫曼-拉罗切有限公司 |
抗生物素抗体及使用方法
|
KR102090849B1
(ko)
|
2012-07-04 |
2020-03-19 |
에프. 호프만-라 로슈 아게 |
공유 결합된 항원-항체 접합체
|
RU2636822C2
(ru)
|
2012-07-13 |
2017-11-28 |
Ф.Хоффманн-Ля Рош Аг |
Способ обнаружения мультиспецифического связывающего агента
|
AU2013293092A1
(en)
*
|
2012-07-23 |
2015-02-26 |
Zymeworks Inc. |
Immunoglobulin constructs comprising selective pairing of the light and heavy chains
|
CN104619715B
(zh)
|
2012-09-14 |
2018-06-05 |
弗·哈夫曼-拉罗切有限公司 |
包含至少两个不同实体的分子的生产和选择方法及其用途
|
US9714291B2
(en)
|
2012-10-05 |
2017-07-25 |
Kyowa Hakko Kirin Co., Ltd |
Heterodimer protein composition
|
WO2014056783A1
(en)
|
2012-10-08 |
2014-04-17 |
Roche Glycart Ag |
Fc-free antibodies comprising two fab-fragments and methods of use
|
PE20150956A1
(es)
|
2012-11-08 |
2015-06-20 |
Hoffmann La Roche |
Proteinas ligantes de antigeno her3 de union a la horquilla beta de her3
|
KR102168562B1
(ko)
*
|
2012-11-19 |
2020-10-22 |
발리오팜 아게 |
Cd20 및 cd95에 결합하는 재조합 이중특이성 항체
|
US9914785B2
(en)
|
2012-11-28 |
2018-03-13 |
Zymeworks Inc. |
Engineered immunoglobulin heavy chain-light chain pairs and uses thereof
|
JP6347490B2
(ja)
|
2012-11-28 |
2018-06-27 |
ザイムワークス,インコーポレイテッド |
遺伝子操作された免疫グロブリン重鎖−軽鎖対およびその使用
|
GB201223276D0
(en)
*
|
2012-12-21 |
2013-02-06 |
Ucb Pharma Sa |
Antibodies and methods of producing same
|
US10968276B2
(en)
|
2013-03-12 |
2021-04-06 |
Xencor, Inc. |
Optimized anti-CD3 variable regions
|
US11053316B2
(en)
|
2013-01-14 |
2021-07-06 |
Xencor, Inc. |
Optimized antibody variable regions
|
US9605084B2
(en)
|
2013-03-15 |
2017-03-28 |
Xencor, Inc. |
Heterodimeric proteins
|
US10487155B2
(en)
|
2013-01-14 |
2019-11-26 |
Xencor, Inc. |
Heterodimeric proteins
|
WO2014110601A1
(en)
|
2013-01-14 |
2014-07-17 |
Xencor, Inc. |
Novel heterodimeric proteins
|
MX2015010843A
(es)
*
|
2013-02-26 |
2016-04-04 |
Roche Glycart Ag |
Moleculas biespecificas de union al antigeno que activan celulas t.
|
MX2015010350A
(es)
*
|
2013-02-26 |
2015-10-29 |
Roche Glycart Ag |
Moleculas de union a antigeno biespecificas que activan la celula t.
|
CA2891493C
(en)
*
|
2013-02-26 |
2022-03-15 |
Roche Glycart Ag |
Bispecific t cell activating antigen binding molecules
|
MX2015012059A
(es)
*
|
2013-03-15 |
2016-01-12 |
Merck Patent Gmbh |
Anticuerpos biespecificos tetravalentes.
|
EP3421495A3
(en)
|
2013-03-15 |
2019-05-15 |
Xencor, Inc. |
Modulation of t cells with bispecific antibodies and fc fusions
|
US10858417B2
(en)
|
2013-03-15 |
2020-12-08 |
Xencor, Inc. |
Heterodimeric proteins
|
KR102049990B1
(ko)
*
|
2013-03-28 |
2019-12-03 |
삼성전자주식회사 |
c-Met 항체 및 VEGF 결합 단편이 연결된 융합 단백질
|
UA118028C2
(uk)
|
2013-04-03 |
2018-11-12 |
Рош Глікарт Аг |
Біспецифічне антитіло, специфічне щодо fap і dr5, антитіло, специфічне щодо dr5, і спосіб їх застосування
|
RU2019108429A
(ru)
|
2013-04-29 |
2019-05-06 |
Ф. Хоффманн-Ля Рош Аг |
Модифицированные асимметричные антитела, связывающие fc-рецептор, и способы их применения
|
ES2746136T3
(es)
|
2013-04-29 |
2020-03-04 |
Hoffmann La Roche |
Anticuerpos modificados de unión a FcRn humano y procedimientos de uso
|
CN105164158A
(zh)
|
2013-04-29 |
2015-12-16 |
豪夫迈·罗氏有限公司 |
消除对FcRn-结合的抗-IGF-1R抗体及其在血管性眼病治疗中的用途
|
WO2015025054A1
(en)
|
2013-08-22 |
2015-02-26 |
Medizinische Universität Wien |
Dye-specific antibodies for prestained molecular weight markers and methods producing the same
|
MX2016003593A
(es)
|
2013-10-11 |
2016-06-02 |
Hoffmann La Roche |
Anticuerpos de cadena ligera variable comun intercambiada de dominio multiespecifico.
|
CN104558194B
(zh)
*
|
2013-10-17 |
2018-04-27 |
泰州迈博太科药业有限公司 |
一类抗CD20-Flex双功能融合蛋白、其制备方法及用途
|
SG10202007189VA
(en)
|
2013-11-21 |
2020-09-29 |
Hoffmann La Roche |
ANTI-alpha-SYNUCLEIN ANTIBODIES AND METHODS OF USE
|
JP6510532B2
(ja)
|
2013-12-20 |
2019-05-08 |
エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト |
二重特異性her2抗体及び使用方法
|
EP3083680B1
(en)
|
2013-12-20 |
2020-01-15 |
F. Hoffmann-La Roche AG |
Humanized anti-tau(ps422) antibodies and methods of use
|
TW201609805A
(zh)
*
|
2013-12-23 |
2016-03-16 |
美國禮來大藥廠 |
結合egfr及met之多功能抗體
|
EP3089759B1
(en)
|
2014-01-03 |
2018-12-05 |
F. Hoffmann-La Roche AG |
Covalently linked polypeptide toxin-antibody conjugates
|
WO2015101586A1
(en)
|
2014-01-03 |
2015-07-09 |
F. Hoffmann-La Roche Ag |
Bispecific anti-hapten/anti-blood brain barrier receptor antibodies, complexes thereof and their use as blood brain barrier shuttles
|
WO2015101587A1
(en)
|
2014-01-03 |
2015-07-09 |
F. Hoffmann-La Roche Ag |
Covalently linked helicar-anti-helicar antibody conjugates and uses thereof
|
EP3851452A1
(en)
|
2014-01-06 |
2021-07-21 |
F. Hoffmann-La Roche AG |
Monovalent blood brain barrier shuttle modules
|
CN110903398B
(zh)
|
2014-01-15 |
2023-08-15 |
豪夫迈·罗氏有限公司 |
具有修饰的FCRN和保持的蛋白A结合性质的Fc区变体
|
CR20160506A
(es)
|
2014-03-28 |
2017-03-10 |
Xencor Inc |
Anticuerpos biespecíficos que se unen a cd38 y cd3
|
SG11201608054YA
(en)
|
2014-04-02 |
2016-10-28 |
Hoffmann La Roche |
Method for detecting multispecific antibody light chain mispairing
|
CA2943943C
(en)
|
2014-04-07 |
2023-01-10 |
Chugai Seiyaku Kabushiki Kaisha |
Immunoactivating antigen-binding molecule
|
EP2930188A1
(en)
*
|
2014-04-13 |
2015-10-14 |
Affimed Therapeutics AG |
Trifunctional antigen-binding molecule
|
KR102223502B1
(ko)
*
|
2014-05-09 |
2021-03-05 |
삼성전자주식회사 |
항 c-Met/항 EGFR/항 Her3 다중 특이 항체 및 이의 이용
|
MX2016014434A
(es)
*
|
2014-05-13 |
2017-02-23 |
Chugai Pharmaceutical Co Ltd |
Molecula de union a antigeno redirigida a celulas t para celulas que tienen funcion de inmunosupresion.
|
EP4026850A1
(en)
|
2014-05-28 |
2022-07-13 |
Zymeworks Inc. |
Modified antigen binding polypeptide constructs and uses thereof
|
US10647768B2
(en)
*
|
2014-05-29 |
2020-05-12 |
Macrogenics, Inc. |
Multi-chain polypeptide-containing tri-specific binding molecules
|
GB201411320D0
(en)
|
2014-06-25 |
2014-08-06 |
Ucb Biopharma Sprl |
Antibody construct
|
MX2016015280A
(es)
|
2014-06-26 |
2017-03-03 |
Hoffmann La Roche |
Anticuerpos anti-bromodesoxiuridina(brdu) y metodos de uso.
|
AR100978A1
(es)
|
2014-06-26 |
2016-11-16 |
Hoffmann La Roche |
LANZADERAS CEREBRALES DE ANTICUERPO HUMANIZADO ANTI-Tau(pS422) Y USOS DE LAS MISMAS
|
TWI693232B
(zh)
|
2014-06-26 |
2020-05-11 |
美商宏觀基因股份有限公司 |
與pd-1和lag-3具有免疫反應性的共價結合的雙抗體和其使用方法
|
US9840553B2
(en)
|
2014-06-28 |
2017-12-12 |
Kodiak Sciences Inc. |
Dual PDGF/VEGF antagonists
|
TW201623329A
(zh)
|
2014-06-30 |
2016-07-01 |
亞佛瑞司股份有限公司 |
針對骨調素截斷變異體的疫苗及單株抗體暨其用途
|
JP2017520575A
(ja)
|
2014-07-01 |
2017-07-27 |
ファイザー・インク |
二重特異的ヘテロ二量体ダイアボディおよびその使用
|
RU2742493C2
(ru)
|
2014-07-10 |
2021-02-08 |
Аффирис Аг |
Вещества и способы для применения при предупреждении и/или лечении болезни гентингтона
|
PE20211533A1
(es)
|
2014-08-04 |
2021-08-16 |
Hoffmann La Roche |
Moleculas biespecificas de unon a antigeno activadoras de celulas t
|
UY36316A
(es)
|
2014-09-26 |
2016-04-29 |
Macrogenics Inc |
Diacuerpos monovalentes biespecíficos que son capaces de unir cd19 y cd3, y usos de los mismos
|
MX2017005148A
(es)
|
2014-11-06 |
2017-08-08 |
Hoffmann La Roche |
Variantes de region fc con union del receptor fc neonatal (fcrn) modificado y metodos de uso.
|
MX2017005150A
(es)
|
2014-11-06 |
2017-08-08 |
Hoffmann La Roche |
Variantes de region fc con propiedades modificadas de union a receptor neonatal fc (fcrn) y proteina a.
|
DK3221355T3
(da)
|
2014-11-20 |
2020-12-07 |
Hoffmann La Roche |
Kombinationsbehandling med T-celleaktiverende bispecifikke antigenbindende molekyler CD3 og folatreceptor 1 (FolR1) samt PD-1-aksebindende antagonister
|
CA2968878A1
(en)
|
2014-11-26 |
2016-06-02 |
Xencor, Inc. |
Heterodimeric antibodies that bind cd3 and cd38
|
US10259887B2
(en)
|
2014-11-26 |
2019-04-16 |
Xencor, Inc. |
Heterodimeric antibodies that bind CD3 and tumor antigens
|
DK3223845T3
(da)
|
2014-11-26 |
2021-08-16 |
Xencor Inc |
Heterodimere antistoffer, der binder cd3 og cd20
|
WO2016087514A1
(en)
|
2014-12-02 |
2016-06-09 |
Cemm - Forschungszentrum Für Molekulare Medizin Gmbh |
Anti-mutant calreticulin antibodies and their use in the diagnosis and therapy of myeloid malignancies
|
WO2016087416A1
(en)
*
|
2014-12-03 |
2016-06-09 |
F. Hoffmann-La Roche Ag |
Multispecific antibodies
|
US10982008B2
(en)
*
|
2014-12-05 |
2021-04-20 |
Merck Patent Gmbh |
Domain-exchanged antibody
|
CA2966551A1
(en)
|
2014-12-18 |
2016-06-23 |
F. Hoffmann-La Roche Ag |
Assay and method for determining cdc eliciting antibodies
|
EP3237449A2
(en)
*
|
2014-12-22 |
2017-11-01 |
Xencor, Inc. |
Trispecific antibodies
|
KR20170105622A
(ko)
|
2015-01-26 |
2017-09-19 |
마크로제닉스, 인크. |
Dr5-결합 도메인을 포함하는 다가 분자
|
TWI773646B
(zh)
|
2015-06-08 |
2022-08-11 |
美商宏觀基因股份有限公司 |
結合lag-3的分子和其使用方法
|
US9862763B2
(en)
|
2015-06-24 |
2018-01-09 |
Hoffmann-La Roche Inc. |
Humanized anti-tau(pS422) antibodies and methods of use
|
WO2017004149A1
(en)
*
|
2015-06-30 |
2017-01-05 |
Boehringer Ingelheim International Gmbh |
Multi-specific binding proteins
|
LT3328419T
(lt)
|
2015-07-30 |
2021-11-10 |
Macrogenics, Inc. |
Pd-1 surišančios molekulės ir jų panaudojimo būdai
|
JP7002446B2
(ja)
|
2015-09-21 |
2022-03-04 |
アプティーボ リサーチ アンド デベロップメント エルエルシー |
Cd3結合ポリペプチド
|
AR106188A1
(es)
|
2015-10-01 |
2017-12-20 |
Hoffmann La Roche |
Anticuerpos anti-cd19 humano humanizados y métodos de utilización
|
PL3356404T3
(pl)
|
2015-10-02 |
2022-01-03 |
F. Hoffmann-La Roche Ag |
Przeciwciała anty-pd1 i sposoby ich stosowania
|
JP6734919B2
(ja)
|
2015-10-02 |
2020-08-05 |
エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft |
同時結合を測定するための細胞ベースのfretアッセイ法
|
AR106201A1
(es)
|
2015-10-02 |
2017-12-20 |
Hoffmann La Roche |
Moléculas biespecíficas de unión a antígeno activadoras de células t
|
AU2016334063B2
(en)
|
2015-10-08 |
2023-05-25 |
Zymeworks Bc Inc. |
Antigen-binding polypeptide constructs comprising kappa and lambda light chains and uses thereof
|
MX2018004177A
(es)
|
2015-10-08 |
2018-09-11 |
Macrogenics Inc |
Terapia de combinacion para el tratamiento de cancer.
|
EP3368568B1
(en)
|
2015-10-29 |
2022-04-06 |
F. Hoffmann-La Roche AG |
Anti-variant fc-region antibodies and methods of use
|
EP3184547A1
(en)
|
2015-10-29 |
2017-06-28 |
F. Hoffmann-La Roche AG |
Anti-tpbg antibodies and methods of use
|
WO2017086367A1
(ja)
|
2015-11-18 |
2017-05-26 |
中外製薬株式会社 |
免疫抑制機能を有する細胞に対するt細胞リダイレクト抗原結合分子を用いた併用療法
|
EP3378488A4
(en)
|
2015-11-18 |
2019-10-30 |
Chugai Seiyaku Kabushiki Kaisha |
METHOD FOR ENHANCING THE HUMORAL IMMUNE RESPONSE
|
CN108699136B
(zh)
|
2015-12-07 |
2022-03-18 |
Xencor股份有限公司 |
结合cd3和psma的异二聚抗体
|
KR20180085740A
(ko)
|
2015-12-09 |
2018-07-27 |
에프. 호프만-라 로슈 아게 |
항-약물 항체의 형성을 감소시키기 위한 ii형 항-cd20 항체
|
EP3389714A4
(en)
|
2015-12-14 |
2019-11-13 |
MacroGenics, Inc. |
BISPECIFIC MOLECULES HAVING IMMUNOREACTIVITY TO PD-1 AND CTLA-4 AND METHODS OF USE
|
BR112018013407A2
(pt)
|
2015-12-30 |
2018-12-18 |
Kodiak Sciences Inc |
anticorpos e conjugados dos mesmos
|
IL259588B2
(en)
|
2016-01-08 |
2023-09-01 |
Hoffmann La Roche |
Methods for the treatment of cea-positive cancer using pd-1 spindle-binding antagonists and bispecific antibodies against anti-cea and anti-cd3
|
TW201730212A
(zh)
|
2016-02-17 |
2017-09-01 |
宏觀基因股份有限公司 |
Ror1-結合分子及其使用方法
|
ES2947230T3
(es)
|
2016-03-22 |
2023-08-03 |
Hoffmann La Roche |
Moléculas biespecíficas para linfocitos T activadas por proteasa
|
US10894823B2
(en)
*
|
2016-03-24 |
2021-01-19 |
Gensun Biopharma Inc. |
Trispecific inhibitors for cancer treatment
|
IL262396B2
(en)
|
2016-04-15 |
2023-09-01 |
Macrogenics Inc |
New b7-h3 binding molecules, drug-antibody conjugates and their uses
|
WO2017218707A2
(en)
|
2016-06-14 |
2017-12-21 |
Xencor, Inc. |
Bispecific checkpoint inhibitor antibodies
|
AR108800A1
(es)
|
2016-06-17 |
2018-09-26 |
Genentech Inc |
Purificación de anticuerpos multiespecíficos
|
CN116063545A
(zh)
|
2016-06-28 |
2023-05-05 |
Xencor股份有限公司 |
结合生长抑素受体2的异源二聚抗体
|
EP3484516A4
(en)
|
2016-07-14 |
2020-03-18 |
Fred Hutchinson Cancer Research Center |
MULTIPLE CONSTRUCTIONS OF BI-SPECIFIC LINK AREAS HAVING A DIFFERENT EPITOPE LINK TO TREAT CANCER
|
US10793632B2
(en)
|
2016-08-30 |
2020-10-06 |
Xencor, Inc. |
Bispecific immunomodulatory antibodies that bind costimulatory and checkpoint receptors
|
JP6976315B2
(ja)
|
2016-09-19 |
2021-12-08 |
エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft |
補体因子に基づくアフィニティークロマトグラフィー
|
JP6785372B2
(ja)
|
2016-09-30 |
2020-11-18 |
エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft |
多重特異性分子の機能分析のためのsprに基づく二重結合アッセイ
|
JP7022123B2
(ja)
|
2016-09-30 |
2022-02-17 |
エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト |
Cd3に対する二重特異性抗体
|
CA3038552A1
(en)
|
2016-09-30 |
2018-04-05 |
Baylor College Of Medicine |
Antibody based gene therapy with tissue-directed expression
|
EP3526241A1
(en)
|
2016-10-14 |
2019-08-21 |
Xencor, Inc. |
Il15/il15r heterodimeric fc-fusion proteins
|
TW201829463A
(zh)
|
2016-11-18 |
2018-08-16 |
瑞士商赫孚孟拉羅股份公司 |
抗hla-g抗體及其用途
|
WO2018098363A2
(en)
|
2016-11-23 |
2018-05-31 |
Bioverativ Therapeutics Inc. |
Bispecific antibodies binding to coagulation factor ix and coagulation factor x
|
WO2018114878A1
(en)
|
2016-12-21 |
2018-06-28 |
F. Hoffmann-La Roche Ag |
Re-use of enzymes in in vitro glycoengineering of antibodies
|
MX2019006123A
(es)
|
2016-12-21 |
2019-08-12 |
Hoffmann La Roche |
Metodo para glicomanipulacion in vitro de anticuerpos.
|
CN110088291A
(zh)
|
2016-12-21 |
2019-08-02 |
豪夫迈·罗氏有限公司 |
用于体外糖工程化抗体的方法
|
EP3558368A4
(en)
|
2016-12-23 |
2020-12-30 |
MacroGenics, Inc. |
ADAM9 BINDING MOLECULES AND THEIR METHODS FOR USE
|
US20190352429A1
(en)
|
2017-02-02 |
2019-11-21 |
Merck Patent Gmbh |
Preferred pairing of antibody domains
|
CN110325209A
(zh)
|
2017-02-24 |
2019-10-11 |
宏观基因有限公司 |
能够结合cd137和肿瘤抗原的双特异性结合分子及其用途
|
SG11201909218RA
(en)
|
2017-04-03 |
2019-11-28 |
Hoffmann La Roche |
Antibodies binding to steap-1
|
CN116375876A
(zh)
|
2017-04-05 |
2023-07-04 |
豪夫迈·罗氏有限公司 |
特异性结合pd1和lag3的双特异性抗体
|
KR102294136B1
(ko)
|
2017-04-05 |
2021-08-26 |
에프. 호프만-라 로슈 아게 |
항-lag3 항체
|
EP3645049A4
(en)
*
|
2017-06-25 |
2021-06-30 |
Systimmune, Inc. |
MULTISPECIFIC ANTIBODIES AND ASSOCIATED PREPARATION AND USE PROCESSES
|
AU2018295119A1
(en)
*
|
2017-06-25 |
2020-02-06 |
Baili-Bio (Chengdu) Pharmaceutical Co., Ltd. |
Multi-specific antibodies and methods of making and using thereof
|
BR112019025105A2
(pt)
|
2017-06-30 |
2020-10-20 |
Zymeworks Inc. |
fabs quiméricos estabilizados
|
CN111132733A
(zh)
|
2017-06-30 |
2020-05-08 |
Xencor股份有限公司 |
含有IL-15/IL-15Rα和抗原结合结构域的靶向异源二聚体Fc融合蛋白
|
EP3625250B1
(en)
|
2017-07-21 |
2021-04-14 |
Trianni, Inc. |
Single chain vh and heavy chain antibodies
|
US11161911B2
(en)
|
2017-10-23 |
2021-11-02 |
Go Therapeutics, Inc. |
Anti-glyco-MUC1 antibodies and their uses
|
US11312770B2
(en)
|
2017-11-08 |
2022-04-26 |
Xencor, Inc. |
Bispecific and monospecific antibodies using novel anti-PD-1 sequences
|
US10981992B2
(en)
|
2017-11-08 |
2021-04-20 |
Xencor, Inc. |
Bispecific immunomodulatory antibodies that bind costimulatory and checkpoint receptors
|
MX2020004921A
(es)
|
2017-11-29 |
2020-08-27 |
Hoffmann La Roche |
Ensayo de anticuerpo antifarmaco con supresion de interferencia del objetivo.
|
RU2020122822A
(ru)
|
2017-12-12 |
2022-01-13 |
Макродженикс, Инк. |
Биспецифичные связывающие cd16 молекулы и их применение при лечении заболеваний
|
CA3086199A1
(en)
|
2017-12-19 |
2019-06-27 |
Xencor, Inc. |
Engineered il-2 fc fusion proteins
|
EP3728317A2
(en)
|
2017-12-21 |
2020-10-28 |
F. Hoffmann-La Roche AG |
Antibodies binding to hla-a2/wt1
|
US11945839B2
(en)
|
2017-12-22 |
2024-04-02 |
Hoffmann-La Roche Inc. |
Depletion of light chain mispaired antibody variants by hydrophobic interaction chromatography
|
JP7436365B2
(ja)
|
2017-12-29 |
2024-02-21 |
エフ. ホフマン-ラ ロシュ アーゲー |
抗vegf抗体及び使用の方法
|
CN111630063A
(zh)
|
2018-01-31 |
2020-09-04 |
豪夫迈·罗氏有限公司 |
稳定化的免疫球蛋白结构域
|
US20200354457A1
(en)
|
2018-01-31 |
2020-11-12 |
Hoffmann-La Roche Inc. |
Bispecific antibodies comprising an antigen-binding site binding to lag3
|
AU2019218959A1
(en)
|
2018-02-08 |
2020-09-03 |
Genentech, Inc. |
Bispecific antigen-binding molecules and methods of use
|
TWI829667B
(zh)
|
2018-02-09 |
2024-01-21 |
瑞士商赫孚孟拉羅股份公司 |
結合gprc5d之抗體
|
JP7337079B2
(ja)
|
2018-02-15 |
2023-09-01 |
マクロジェニクス,インコーポレーテッド |
変異型cd3結合ドメイン、及び疾患の治療のための併用療法におけるその使用
|
KR20230042407A
(ko)
|
2018-03-29 |
2023-03-28 |
제넨테크, 인크. |
포유류 세포들에서 젖분비자극 활성의 조절
|
US10982006B2
(en)
|
2018-04-04 |
2021-04-20 |
Xencor, Inc. |
Heterodimeric antibodies that bind fibroblast activation protein
|
WO2019204655A1
(en)
|
2018-04-18 |
2019-10-24 |
Xencor, Inc. |
Tim-3 targeted heterodimeric fusion proteins containing il-15/il-15ra fc-fusion proteins and tim-3 antigen binding domains
|
KR20210010862A
(ko)
|
2018-04-18 |
2021-01-28 |
젠코어 인코포레이티드 |
IL-15/IL-15Rα Fc-융합 단백질 및 PD-1 항원 결합 도메인을 함유하는 PD-1 표적화 이종이량체 융합 단백질 및 이의 용도
|
AR114789A1
(es)
|
2018-04-18 |
2020-10-14 |
Hoffmann La Roche |
Anticuerpos anti-hla-g y uso de los mismos
|
AR115052A1
(es)
|
2018-04-18 |
2020-11-25 |
Hoffmann La Roche |
Anticuerpos multiespecíficos y utilización de los mismos
|
EP3802609A2
(en)
|
2018-05-24 |
2021-04-14 |
Janssen Biotech, Inc. |
Psma binding agents and uses thereof
|
TW202016151A
(zh)
|
2018-06-09 |
2020-05-01 |
德商百靈佳殷格翰國際股份有限公司 |
針對癌症治療之多特異性結合蛋白
|
TWI754157B
(zh)
|
2018-07-25 |
2022-02-01 |
大陸商信達生物製藥(蘇州)有限公司 |
抗tigit抗體及其用途
|
MA50586A
(fr)
|
2018-08-09 |
2020-09-16 |
Regeneron Pharma |
Procédés d'évaluation de l'affinité de liaison d'une variante d'anticorps au récepteur fc néonatal
|
JP2022503959A
(ja)
|
2018-10-03 |
2022-01-12 |
ゼンコア インコーポレイテッド |
Il-12ヘテロ二量体fc-融合タンパク質
|
CN109633053B
(zh)
*
|
2018-12-19 |
2021-04-30 |
杭州奕安济世生物药业有限公司 |
细胞培养物蛋白质表达量和蛋白质聚集体量的检测方法
|
MX2021007307A
(es)
|
2018-12-21 |
2021-07-07 |
Hoffmann La Roche |
Anticuerpos que se unen a cd3.
|
CA3124796A1
(en)
|
2018-12-24 |
2020-07-02 |
Sanofi |
Multispecific binding proteins with mutant fab domains
|
US20220073630A1
(en)
|
2018-12-28 |
2022-03-10 |
Hoffmann-La Roche, Inc. |
A peptide-mhc-i-antibody fusion protein for therapeutic use in a patient with amplified immune response
|
CN113227789A
(zh)
|
2018-12-30 |
2021-08-06 |
豪夫迈·罗氏有限公司 |
基于pH梯度SPR的结合测定
|
EP3930850A1
(en)
|
2019-03-01 |
2022-01-05 |
Xencor, Inc. |
Heterodimeric antibodies that bind enpp3 and cd3
|
CN113677701A
(zh)
|
2019-03-29 |
2021-11-19 |
豪夫迈·罗氏有限公司 |
产生亲合结合多特异性抗体的方法
|
CN113646622A
(zh)
|
2019-03-29 |
2021-11-12 |
豪夫迈·罗氏有限公司 |
用于多价分子的功能分析的基于spr的结合测定
|
AR118720A1
(es)
|
2019-04-19 |
2021-10-27 |
Janssen Biotech Inc |
Métodos para tratar el cáncer de próstata con un anticuerpo anti-psma / cd3
|
EP3969907A1
(en)
|
2019-05-13 |
2022-03-23 |
F. Hoffmann-La Roche AG |
Interference-suppressed pharmacokinetic immunoassay
|
WO2020254356A1
(en)
|
2019-06-19 |
2020-12-24 |
F. Hoffmann-La Roche Ag |
Method for the generation of a multivalent, bispecific antibody expressing cell by targeted integration of multiple expression cassettes in a defined organization
|
MX2021015536A
(es)
|
2019-06-19 |
2022-02-10 |
Hoffmann La Roche |
Metodo para la generacion de una celula que expresa proteina mediante integracion dirigida usando acido ribonucleico mensajero (arnm) de cre.
|
CN114258403A
(zh)
|
2019-06-19 |
2022-03-29 |
豪夫迈·罗氏有限公司 |
通过以限定的组织形式靶向整合多个表达盒来产生多价多特异性抗体表达细胞的方法
|
MX2021015538A
(es)
|
2019-06-19 |
2022-02-10 |
Hoffmann La Roche |
Metodo para la generacion de una celula que expresa un anticuerpo biespecifico bivalente mediante la integracion dirigida de multiples casetes de expresion en una organizacion definida.
|
KR20220024637A
(ko)
|
2019-06-19 |
2022-03-03 |
에프. 호프만-라 로슈 아게 |
정의된 조직의 다수 발현 카세트들의 표적화 통합에 의한 3가 항체 발현 세포의 생성 방법
|
AU2020306672B2
(en)
|
2019-06-26 |
2023-08-24 |
F. Hoffmann-La Roche Ag |
Mammalian cell lines with SIRT-1 gene knockout
|
AR119393A1
(es)
|
2019-07-15 |
2021-12-15 |
Hoffmann La Roche |
Anticuerpos que se unen a nkg2d
|
EP4003526A2
(en)
|
2019-07-31 |
2022-06-01 |
F. Hoffmann-La Roche AG |
Antibodies binding to gprc5d
|
CN114174338A
(zh)
|
2019-07-31 |
2022-03-11 |
豪夫迈·罗氏有限公司 |
与gprc5d结合的抗体
|
JP2022543669A
(ja)
*
|
2019-08-08 |
2022-10-13 |
リジェネロン・ファーマシューティカルズ・インコーポレイテッド |
新規抗原結合分子フォーマット
|
MX2022003212A
(es)
|
2019-09-18 |
2022-04-25 |
Genentech Inc |
Anticuerpos anti-klk7, anticuerpos anti-klk5, anticuerpos multiespecificos anti-klk5/klk7 y metodos de uso.
|
EP4041312A4
(en)
|
2019-10-10 |
2023-12-20 |
Kodiak Sciences Inc. |
METHOD FOR TREATING AN EYE DISORDER
|
CN114641270A
(zh)
|
2019-11-15 |
2022-06-17 |
豪夫迈·罗氏有限公司 |
防止水性蛋白质溶液中可见颗粒的形成
|
AU2020403913A1
(en)
|
2019-12-18 |
2022-06-09 |
F. Hoffmann-La Roche Ag |
Bispecific anti-CCL2 antibodies
|
US20210230278A1
(en)
|
2019-12-18 |
2021-07-29 |
Hoffmann-La Roche Inc. |
Antibodies binding to HLA-A2/MAGE-A4
|
EP4081294A2
(en)
|
2019-12-23 |
2022-11-02 |
Genentech, Inc. |
Apolipoprotein l1-specific antibodies and methods of use
|
TWI766512B
(zh)
|
2020-01-02 |
2022-06-01 |
瑞士商赫孚孟拉羅股份公司 |
用於判定腦中的治療性抗體量之方法
|
CA3167657A1
(en)
|
2020-01-15 |
2021-07-22 |
F. Hoffmann-La Roche Ag |
Methods to decrease impurities from recombinant protein manufacturing processes
|
CN115315512A
(zh)
|
2020-03-26 |
2022-11-08 |
基因泰克公司 |
具有降低的宿主细胞蛋白质的经修饰的哺乳动物细胞
|
US11919956B2
(en)
|
2020-05-14 |
2024-03-05 |
Xencor, Inc. |
Heterodimeric antibodies that bind prostate specific membrane antigen (PSMA) and CD3
|
CN115605184A
(zh)
|
2020-05-15 |
2023-01-13 |
豪夫迈·罗氏有限公司(Ch) |
防止胃肠外蛋白质溶液中的可见颗粒形成
|
CN115605185A
(zh)
|
2020-05-19 |
2023-01-13 |
豪夫迈·罗氏有限公司(Ch) |
螯合剂用于防止胃肠外蛋白质溶液中形成可见颗粒的用途
|
AU2021288916A1
(en)
|
2020-06-08 |
2022-11-24 |
F.Hoffmann-La Roche Ag |
Anti-HBV antibodies and methods of use
|
IL298923A
(en)
|
2020-06-16 |
2023-02-01 |
Hoffmann La Roche |
A method for determining the free antigen of an antibody in a sample
|
BR112022025574A2
(pt)
|
2020-06-19 |
2023-01-03 |
Hoffmann La Roche |
Anticorpos que se ligam a cd3, polinucleotídeo isolado, célula hospedeira, método para produzir um anticorpo que se liga a cd3 e para tratar uma doença em um indivíduo, composição farmacêutica, anticorpo para uso e invenção
|
WO2021255146A1
(en)
|
2020-06-19 |
2021-12-23 |
F. Hoffmann-La Roche Ag |
Antibodies binding to cd3 and cea
|
US11780920B2
(en)
|
2020-06-19 |
2023-10-10 |
Hoffmann-La Roche Inc. |
Antibodies binding to CD3 and CD19
|
AR122656A1
(es)
|
2020-06-19 |
2022-09-28 |
Hoffmann La Roche |
Anticuerpos que se unen a cd3 / folr1
|
WO2021262783A1
(en)
|
2020-06-24 |
2021-12-30 |
Genentech, Inc. |
Apoptosis resistant cell lines
|
EP4175650A1
(en)
|
2020-07-06 |
2023-05-10 |
Kiromic BioPharma, Inc. |
Mesothelin isoform binding molecules and chimeric pd1 receptor molecules, cells containing the same and uses thereof
|
JP2023532764A
(ja)
|
2020-07-07 |
2023-07-31 |
エフ. ホフマン-ラ ロシュ アーゲー |
治療用タンパク質製剤の安定剤としての代替界面活性剤
|
AU2021308653A1
(en)
|
2020-07-17 |
2023-02-16 |
Genentech, Inc. |
Anti-Notch2 antibodies and methods of use
|
AU2021329378A1
(en)
|
2020-08-19 |
2023-03-23 |
Xencor, Inc. |
Anti-CD28 compositions
|
JP2023539201A
(ja)
|
2020-08-28 |
2023-09-13 |
ジェネンテック, インコーポレイテッド |
宿主細胞タンパク質のCRISPR/Cas9マルチプレックスノックアウト
|
CA3191328A1
(en)
|
2020-09-21 |
2022-03-24 |
Genentech, Inc. |
Purification of multispecific antibodies
|
IL301366A
(en)
|
2020-09-24 |
2023-05-01 |
Hoffmann La Roche |
Mammalian cell lines with genetic knockout
|
TW202233671A
(zh)
|
2020-10-20 |
2022-09-01 |
美商建南德克公司 |
Peg結合抗mertk抗體及其使用方法
|
CA3202233A1
(en)
|
2020-11-18 |
2022-05-27 |
Kiromic BioPharma, Inc. |
Gamma-delta t cell manufacturing processes and chimeric pd1 receptor molecules
|
CN116782937A
(zh)
|
2020-12-10 |
2023-09-19 |
优特力克斯有限公司 |
抗pd-1抗体及其用途
|
EP4263609A1
(en)
|
2020-12-17 |
2023-10-25 |
F. Hoffmann-La Roche AG |
Anti-hla-g antibodies and use thereof
|
WO2022136140A1
(en)
|
2020-12-22 |
2022-06-30 |
F. Hoffmann-La Roche Ag |
Oligonucleotides targeting xbp1
|
WO2022135467A1
(zh)
|
2020-12-23 |
2022-06-30 |
信达生物制药(苏州)有限公司 |
抗b7-h3抗体及其用途
|
JP2024502095A
(ja)
*
|
2020-12-29 |
2024-01-17 |
サムソン バイオロジクス カンパニー リミテッド |
二重または多重特異性抗体{Bi or Multi-Specific Antibody}
|
CN114716548A
(zh)
|
2021-01-05 |
2022-07-08 |
(株)爱恩德生物 |
抗-fgfr3抗体及其用途
|
US20240059789A1
(en)
|
2021-01-28 |
2024-02-22 |
Janssen Biotech, Inc. |
Psma binding proteins and uses thereof
|
JP2024509695A
(ja)
|
2021-02-03 |
2024-03-05 |
ジェネンテック, インコーポレイテッド |
多重特異性結合タンパク質分解プラットフォームおよび使用方法
|
EP4295154A1
(en)
|
2021-02-18 |
2023-12-27 |
F. Hoffmann-La Roche AG |
Method for resolving complex, multistep antibody interactions
|
WO2022174813A1
(zh)
*
|
2021-02-19 |
2022-08-25 |
信达生物制药(苏州)有限公司 |
抗GPRC5DxBCMAxCD3三特异性抗体及其用途
|
CN117157319A
(zh)
|
2021-03-09 |
2023-12-01 |
Xencor股份有限公司 |
结合cd3和cldn6的异二聚抗体
|
WO2022192586A1
(en)
|
2021-03-10 |
2022-09-15 |
Xencor, Inc. |
Heterodimeric antibodies that bind cd3 and gpc3
|
WO2022192647A1
(en)
|
2021-03-12 |
2022-09-15 |
Genentech, Inc. |
Anti-klk7 antibodies, anti-klk5 antibodies, multispecific anti-klk5/klk7 antibodies, and methods of use
|
EP4320444A1
(en)
|
2021-04-09 |
2024-02-14 |
F. Hoffmann-La Roche AG |
Process for selecting cell clones expressing a heterologous polypeptide
|
CA3215965A1
(en)
|
2021-04-19 |
2022-10-27 |
Amy Shen |
Modified mammalian cells
|
EP4341385A1
(en)
|
2021-05-21 |
2024-03-27 |
Genentech, Inc. |
Modified cells for the production of a recombinant product of interest
|
CN113278071B
(zh)
|
2021-05-27 |
2021-12-21 |
江苏荃信生物医药股份有限公司 |
抗人干扰素α受体1单克隆抗体及其应用
|
TW202317625A
(zh)
*
|
2021-06-17 |
2023-05-01 |
德商百靈佳殷格翰國際股份有限公司 |
新穎三特異性結合分子
|
WO2022263501A1
(en)
|
2021-06-18 |
2022-12-22 |
F. Hoffmann-La Roche Ag |
Bispecific anti-ccl2 antibodies
|
KR20240032930A
(ko)
|
2021-07-13 |
2024-03-12 |
제넨테크, 인크. |
사이토카인 방출 증후군을 예측하기 위한 다변량 모델
|
CN117642427A
(zh)
*
|
2021-07-14 |
2024-03-01 |
江苏恒瑞医药股份有限公司 |
特异性结合cd38、bcma和cd3的抗原结合分子及其医药用途
|
AU2022315528A1
(en)
|
2021-07-22 |
2023-10-19 |
F. Hoffmann-La Roche Ag |
Heterodimeric fc domain antibodies
|
WO2023012147A1
(en)
|
2021-08-03 |
2023-02-09 |
F. Hoffmann-La Roche Ag |
Bispecific antibodies and methods of use
|
CN113683694B
(zh)
|
2021-09-03 |
2022-05-13 |
江苏荃信生物医药股份有限公司 |
一种抗人tslp单克隆抗体及其应用
|
CN113603775B
(zh)
|
2021-09-03 |
2022-05-20 |
江苏荃信生物医药股份有限公司 |
抗人白介素-33单克隆抗体及其应用
|
WO2023094282A1
(en)
|
2021-11-25 |
2023-06-01 |
F. Hoffmann-La Roche Ag |
Quantification of low amounts of antibody sideproducts
|
AR127887A1
(es)
|
2021-12-10 |
2024-03-06 |
Hoffmann La Roche |
Anticuerpos que se unen a cd3 y plap
|
WO2023117325A1
(en)
|
2021-12-21 |
2023-06-29 |
F. Hoffmann-La Roche Ag |
Method for the determination of hydrolytic activity
|
WO2023129974A1
(en)
|
2021-12-29 |
2023-07-06 |
Bristol-Myers Squibb Company |
Generation of landing pad cell lines
|
WO2023141445A1
(en)
|
2022-01-19 |
2023-07-27 |
Genentech, Inc. |
Anti-notch2 antibodies and conjugates and methods of use
|
WO2023175171A1
(en)
|
2022-03-18 |
2023-09-21 |
Inserm (Institut National De La Sante Et De La Recherche Medicale) |
Bk polyomavirus antibodies and uses thereof
|
WO2023202967A1
(en)
|
2022-04-19 |
2023-10-26 |
F. Hoffmann-La Roche Ag |
Improved production cells
|
WO2023232961A1
(en)
|
2022-06-03 |
2023-12-07 |
F. Hoffmann-La Roche Ag |
Improved production cells
|
WO2024020564A1
(en)
|
2022-07-22 |
2024-01-25 |
Genentech, Inc. |
Anti-steap1 antigen-binding molecules and uses thereof
|
WO2024079010A1
(en)
|
2022-10-10 |
2024-04-18 |
F. Hoffmann-La Roche Ag |
Combination therapy of a gprc5d tcb and cd38 antibodies
|
WO2024079015A1
(en)
|
2022-10-10 |
2024-04-18 |
F. Hoffmann-La Roche Ag |
Combination therapy of a gprc5d tcb and imids
|
WO2024079009A1
(en)
|
2022-10-10 |
2024-04-18 |
F. Hoffmann-La Roche Ag |
Combination therapy of a gprc5d tcb and proteasome inhibitors
|
WO2024079069A1
(en)
|
2022-10-12 |
2024-04-18 |
F. Hoffmann-La Roche Ag |
Method for classifying cells
|
CN117805397A
(zh)
*
|
2024-02-29 |
2024-04-02 |
军科正源(北京)药物研究有限责任公司 |
检测游离vegf的方法
|