KR102698327B1 - Pi3k 억제제의 염 및 이의 제조 공정 - Google Patents

Pi3k 억제제의 염 및 이의 제조 공정 Download PDF

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KR102698327B1
KR102698327B1 KR1020177027583A KR20177027583A KR102698327B1 KR 102698327 B1 KR102698327 B1 KR 102698327B1 KR 1020177027583 A KR1020177027583 A KR 1020177027583A KR 20177027583 A KR20177027583 A KR 20177027583A KR 102698327 B1 KR102698327 B1 KR 102698327B1
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compound
formula
lymphoma
salt
cancer
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KR20170132185A (ko
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레이 차오
링카이 웡
지아청 저우
융춘 판
마이클 샤
중지앙 지아
핑리 류
치옌 린
윌리암 프릿제
데이비드 멜로니
충성 에릭 스
타이-위웬 웨
바카르 샤리프
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인사이트 홀딩스 코포레이션
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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
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KR1020177027583A 2015-02-27 2016-02-26 Pi3k 억제제의 염 및 이의 제조 공정 Active KR102698327B1 (ko)

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US201562121697P 2015-02-27 2015-02-27
US62/121,697 2015-02-27
PCT/US2016/019741 WO2016138363A1 (en) 2015-02-27 2016-02-26 Salts of pi3k inhibitor and processes for their preparation

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US (4) US10336759B2 (https=)
EP (3) EP4183789A1 (https=)
JP (2) JP6816005B2 (https=)
KR (2) KR102698327B1 (https=)
CN (4) CN117777139A (https=)
AR (1) AR103804A1 (https=)
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KR101763656B1 (ko) 2009-06-29 2017-08-01 인사이트 홀딩스 코포레이션 Ｐｉ3ｋ 저해물질로서의 피리미디논
EP3660016A1 (en) 2010-12-20 2020-06-03 Incyte Holdings Corporation N-(1-(substituted-phenyl)ethyl)-9h-purin-6-amines as pi3k inhibitors
PT3513793T (pt) 2011-09-02 2021-05-10 Incyte Holdings Corp Heterociclilaminas como inibidores de pi3k
AR090548A1 (es) 2012-04-02 2014-11-19 Incyte Corp Azaheterociclobencilaminas biciclicas como inhibidores de pi3k
TWI687220B (zh) * 2013-03-01 2020-03-11 美商英塞特控股公司 吡唑并嘧啶衍生物治療PI3Kδ相關病症之用途
SI3129021T1 (sl) 2014-04-08 2021-07-30 Incyte Corporation Zdravljenje malignosti B-celic s kombinacijo zaviralcev JAK in PI3K
WO2015191677A1 (en) 2014-06-11 2015-12-17 Incyte Corporation Bicyclic heteroarylaminoalkyl phenyl derivatives as pi3k inhibitors
SG10201907576SA (en) 2015-02-27 2019-09-27 Incyte Corp Salts of pi3k inhibitor and processes for their preparation
US9732097B2 (en) 2015-05-11 2017-08-15 Incyte Corporation Process for the synthesis of a phosphoinositide 3-kinase inhibitor
US9988401B2 (en) 2015-05-11 2018-06-05 Incyte Corporation Crystalline forms of a PI3K inhibitor
ES2830446T3 (es) 2015-12-11 2021-06-03 Sichuan Kelun Biotech Biopharmaceutical Co Ltd Derivado de azetidina, método de preparación del mismo y uso del mismo
BR112020018094A2 (pt) 2018-03-08 2020-12-22 Incyte Corporation Compostos de aminopirazina diol como inibidores de pi3k-¿
SG11202011680YA (en) * 2018-06-01 2020-12-30 Incyte Corp Dosing regimen for the treatment of pi3k related disorders
US11046658B2 (en) 2018-07-02 2021-06-29 Incyte Corporation Aminopyrazine derivatives as PI3K-γ inhibitors
WO2022115120A1 (en) 2020-11-30 2022-06-02 Incyte Corporation Combination therapy with an anti-cd19 antibody and parsaclisib
EP4251138A1 (en) 2020-11-30 2023-10-04 Incyte Corporation Combination therapy with an anti-cd19 antibody and parsaclisib
US20230190755A1 (en) 2021-12-16 2023-06-22 Incyte Corporation Topical formulations of PI3K-delta inhibitors
CN114409654A (zh) * 2021-12-30 2022-04-29 安徽普利药业有限公司 一种btk抑制剂的中间体合成方法

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