JPS52106897A - Synthesis of piperazine derivatives - Google Patents
Synthesis of piperazine derivativesInfo
- Publication number
- JPS52106897A JPS52106897A JP176877A JP176877A JPS52106897A JP S52106897 A JPS52106897 A JP S52106897A JP 176877 A JP176877 A JP 176877A JP 176877 A JP176877 A JP 176877A JP S52106897 A JPS52106897 A JP S52106897A
- Authority
- JP
- Japan
- Prior art keywords
- piperazine derivatives
- lower alkyl
- synthesis
- alkyl
- alcyclic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 150000004885 piperazines Chemical class 0.000 title abstract 2
- 229940066771 systemic antihistamines piperazine derivative Drugs 0.000 title abstract 2
- 230000015572 biosynthetic process Effects 0.000 title 1
- 238000003786 synthesis reaction Methods 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 5
- 125000003118 aryl group Chemical group 0.000 abstract 1
- JOHZPMXAZQZXHR-UHFFFAOYSA-N pipemidic acid Chemical compound N1=C2N(CC)C=C(C(O)=O)C(=O)C2=CN=C1N1CCNCC1 JOHZPMXAZQZXHR-UHFFFAOYSA-N 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Landscapes
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
PURPOSE: Piperazine derivatives of formula I (R is H, lower alkyl, alcyclic alkyl, aryl, etc.; R1 is lower alkyl; R2 is H, lower alkyl; R', R" are H, lower alkyl) and inorganic salts thereof; for example, 2-(1-piperazinyl)-8-ethyl-5,8-dihydro5-oxo-pyrido [2,3-d] pyrimidine-6-carboxylic acid.
COPYRIGHT: (C)1977,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP176877A JPS52106897A (en) | 1977-01-10 | 1977-01-10 | Synthesis of piperazine derivatives |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP176877A JPS52106897A (en) | 1977-01-10 | 1977-01-10 | Synthesis of piperazine derivatives |
Related Parent Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP8128872A Division JPS5336478B2 (en) | 1972-03-16 | 1972-08-14 |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS52106897A true JPS52106897A (en) | 1977-09-07 |
JPS5625234B2 JPS5625234B2 (en) | 1981-06-11 |
Family
ID=11510749
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP176877A Granted JPS52106897A (en) | 1977-01-10 | 1977-01-10 | Synthesis of piperazine derivatives |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS52106897A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0721402U (en) * | 1993-09-24 | 1995-04-18 | 株式会社小原産業 | Caster folding storage type carrier |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SI2448938T1 (en) | 2009-06-29 | 2014-08-29 | Incyte Corporation Experimental Station | Pyrimidinones as pi3k inhibitors |
US9062055B2 (en) | 2010-06-21 | 2015-06-23 | Incyte Corporation | Fused pyrrole derivatives as PI3K inhibitors |
ES2764848T3 (en) | 2010-12-20 | 2020-06-04 | Incyte Holdings Corp | N- (1- (substituted phenyl) ethyl) -9H-purine-6-amines as PI3K inhibitors |
WO2012135009A1 (en) | 2011-03-25 | 2012-10-04 | Incyte Corporation | Pyrimidine-4,6-diamine derivatives as pi3k inhibitors |
HUE030869T2 (en) | 2011-09-02 | 2017-06-28 | Incyte Holdings Corp | Heterocyclylamines as pi3k inhibitors |
AR090548A1 (en) | 2012-04-02 | 2014-11-19 | Incyte Corp | BICYCLIC AZAHETEROCICLOBENCILAMINS AS PI3K INHIBITORS |
WO2015191677A1 (en) | 2014-06-11 | 2015-12-17 | Incyte Corporation | Bicyclic heteroarylaminoalkyl phenyl derivatives as pi3k inhibitors |
TWI748941B (en) | 2015-02-27 | 2021-12-11 | 美商英塞特公司 | Salts and processes of preparing a pi3k inhibitor |
WO2016183063A1 (en) | 2015-05-11 | 2016-11-17 | Incyte Corporation | Crystalline forms of a pi3k inhibitor |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS4955694A (en) * | 1972-08-02 | 1974-05-30 |
-
1977
- 1977-01-10 JP JP176877A patent/JPS52106897A/en active Granted
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS4955694A (en) * | 1972-08-02 | 1974-05-30 |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0721402U (en) * | 1993-09-24 | 1995-04-18 | 株式会社小原産業 | Caster folding storage type carrier |
Also Published As
Publication number | Publication date |
---|---|
JPS5625234B2 (en) | 1981-06-11 |
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