MX342128B - Compuestos farmaceuticos. - Google Patents

Compuestos farmaceuticos.

Info

Publication number
MX342128B
MX342128B MX2011006643A MX2011006643A MX342128B MX 342128 B MX342128 B MX 342128B MX 2011006643 A MX2011006643 A MX 2011006643A MX 2011006643 A MX2011006643 A MX 2011006643A MX 342128 B MX342128 B MX 342128B
Authority
MX
Mexico
Prior art keywords
compounds
pharmaceutical compounds
compositions
faah
enzyme
Prior art date
Application number
MX2011006643A
Other languages
English (en)
Other versions
MX2011006643A (es
Inventor
Alexander Learmonth David
Manuel Vieira Araújo Soares Da Silva Patricio
Beliaev Alexander
Erno Kiss Laszlo
Patricia Da Costa Pereira Rosa Carla
Gusmão De Noronha Rita
Nuno Leal Palma Pedro
Original Assignee
Bial - Portela & C A S A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42288334&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX342128(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bial - Portela & C A S A filed Critical Bial - Portela & C A S A
Publication of MX2011006643A publication Critical patent/MX2011006643A/es
Publication of MX342128B publication Critical patent/MX342128B/es

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    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
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    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
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    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
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    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
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    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10—Spiro-condensed systems
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Abstract

La invención se refiere a compuesto y composiciones para inhibir la enzima hidrolasa de amida de ácido graso (FAAH), el uso de los compuestos en la terapia y, en particular, para el tratamiento o prevención de afecciones cuyo desarrollo o síntomas están relacionados con los sustratos de la enzima FAAH, y métodos de tratamiento o prevención usando los compuestos y composiciones.
MX2011006643A 2008-12-24 2009-12-23 Compuestos farmaceuticos. MX342128B (es)

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US14064008P 2008-12-24 2008-12-24
US15928109P 2009-03-11 2009-03-11
US17471209P 2009-05-01 2009-05-01
US22116609P 2009-06-29 2009-06-29
US24247209P 2009-09-15 2009-09-15
PCT/PT2009/000080 WO2010074588A2 (en) 2008-12-24 2009-12-23 Pharmaceutical compounds

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JP2015071622A (ja) 2015-04-16
WO2010074588A2 (en) 2010-07-01
CA2747784C (en) 2018-07-31
KR20110130388A (ko) 2011-12-05
US20120065191A1 (en) 2012-03-15
KR101715190B1 (ko) 2017-03-10
JP2012513990A (ja) 2012-06-21
RU2011129416A (ru) 2013-01-27
BRPI0923819A2 (pt) 2019-11-19
CN105399731A (zh) 2016-03-16
ZA201104336B (en) 2016-10-26
IL213747A (en) 2017-01-31
MX2011006643A (es) 2011-07-29
TW201028408A (en) 2010-08-01
CN102333568A (zh) 2012-01-25
WO2010074588A3 (en) 2011-05-19
AU2009330821A1 (en) 2011-06-23
WO2010074588A8 (en) 2011-10-06
NZ593418A (en) 2013-10-25
RU2553451C2 (ru) 2015-06-20
SG172301A1 (en) 2011-07-28
US9353082B2 (en) 2016-05-31
JP5657566B2 (ja) 2015-01-21
TWI469979B (zh) 2015-01-21
CN102333568B (zh) 2016-01-20
AU2009330821B2 (en) 2015-06-11
CA2747784A1 (en) 2010-07-01
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