MX342128B - Compuestos farmaceuticos. - Google Patents
Compuestos farmaceuticos.Info
- Publication number
- MX342128B MX342128B MX2011006643A MX2011006643A MX342128B MX 342128 B MX342128 B MX 342128B MX 2011006643 A MX2011006643 A MX 2011006643A MX 2011006643 A MX2011006643 A MX 2011006643A MX 342128 B MX342128 B MX 342128B
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- MX
- Mexico
- Prior art keywords
- compounds
- pharmaceutical compounds
- compositions
- faah
- enzyme
- Prior art date
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- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
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- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
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- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
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- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
- C07D491/113—Spiro-condensed systems with two or more oxygen atoms as ring hetero atoms in the oxygen-containing ring
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Abstract
La invención se refiere a compuesto y composiciones para inhibir la enzima hidrolasa de amida de ácido graso (FAAH), el uso de los compuestos en la terapia y, en particular, para el tratamiento o prevención de afecciones cuyo desarrollo o síntomas están relacionados con los sustratos de la enzima FAAH, y métodos de tratamiento o prevención usando los compuestos y composiciones.
Applications Claiming Priority (6)
Application Number | Priority Date | Filing Date | Title |
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US14064008P | 2008-12-24 | 2008-12-24 | |
US15928109P | 2009-03-11 | 2009-03-11 | |
US17471209P | 2009-05-01 | 2009-05-01 | |
US22116609P | 2009-06-29 | 2009-06-29 | |
US24247209P | 2009-09-15 | 2009-09-15 | |
PCT/PT2009/000080 WO2010074588A2 (en) | 2008-12-24 | 2009-12-23 | Pharmaceutical compounds |
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MX2011006643A MX2011006643A (es) | 2011-07-29 |
MX342128B true MX342128B (es) | 2016-09-14 |
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MX2011006643A MX342128B (es) | 2008-12-24 | 2009-12-23 | Compuestos farmaceuticos. |
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US (1) | US9353082B2 (es) |
EP (1) | EP2382012A2 (es) |
JP (2) | JP5657566B2 (es) |
KR (1) | KR101715190B1 (es) |
CN (2) | CN102333568B (es) |
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AU (1) | AU2009330821B2 (es) |
BR (2) | BR122013027950A2 (es) |
CA (1) | CA2747784C (es) |
IL (1) | IL213747A (es) |
MX (1) | MX342128B (es) |
NZ (1) | NZ593418A (es) |
RU (1) | RU2553451C2 (es) |
SG (1) | SG172301A1 (es) |
TW (1) | TWI469979B (es) |
WO (1) | WO2010074588A2 (es) |
ZA (1) | ZA201104336B (es) |
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- 2009-12-23 SG SG2011045465A patent/SG172301A1/en unknown
- 2009-12-23 TW TW98144476A patent/TWI469979B/zh not_active IP Right Cessation
- 2009-12-23 AU AU2009330821A patent/AU2009330821B2/en not_active Ceased
- 2009-12-23 JP JP2011543458A patent/JP5657566B2/ja not_active Expired - Fee Related
- 2009-12-23 RU RU2011129416/04A patent/RU2553451C2/ru active
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2011
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- 2011-06-23 IL IL213747A patent/IL213747A/en not_active IP Right Cessation
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Also Published As
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JP2012513990A (ja) | 2012-06-21 |
WO2010074588A2 (en) | 2010-07-01 |
BRPI0923819B1 (pt) | 2021-11-09 |
AU2009330821B2 (en) | 2015-06-11 |
JP5657566B2 (ja) | 2015-01-21 |
MX2011006643A (es) | 2011-07-29 |
RU2011129416A (ru) | 2013-01-27 |
CA2747784C (en) | 2018-07-31 |
CN102333568B (zh) | 2016-01-20 |
JP2015071622A (ja) | 2015-04-16 |
US9353082B2 (en) | 2016-05-31 |
CA2747784A1 (en) | 2010-07-01 |
RU2553451C2 (ru) | 2015-06-20 |
IL213747A (en) | 2017-01-31 |
NZ593418A (en) | 2013-10-25 |
BRPI0923819A2 (pt) | 2019-11-19 |
TW201028408A (en) | 2010-08-01 |
SG172301A1 (en) | 2011-07-28 |
WO2010074588A8 (en) | 2011-10-06 |
ZA201104336B (en) | 2016-10-26 |
AU2009330821A1 (en) | 2011-06-23 |
AR075111A1 (es) | 2011-03-09 |
EP2382012A2 (en) | 2011-11-02 |
KR101715190B1 (ko) | 2017-03-10 |
BR122013027950A2 (pt) | 2019-12-10 |
US20120065191A1 (en) | 2012-03-15 |
WO2010074588A3 (en) | 2011-05-19 |
TWI469979B (zh) | 2015-01-21 |
CN102333568A (zh) | 2012-01-25 |
CN105399731A (zh) | 2016-03-16 |
KR20110130388A (ko) | 2011-12-05 |
IL213747A0 (en) | 2011-07-31 |
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