JP6463672B2 - Tcrアルファ欠損t細胞を増殖させるためのプレtアルファまたはその機能性変種の使用 - Google Patents
Tcrアルファ欠損t細胞を増殖させるためのプレtアルファまたはその機能性変種の使用 Download PDFInfo
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- JP6463672B2 JP6463672B2 JP2015514051A JP2015514051A JP6463672B2 JP 6463672 B2 JP6463672 B2 JP 6463672B2 JP 2015514051 A JP2015514051 A JP 2015514051A JP 2015514051 A JP2015514051 A JP 2015514051A JP 6463672 B2 JP6463672 B2 JP 6463672B2
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0636—T lymphocytes
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- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
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- C07K14/70578—NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
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- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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- C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
- C07K2317/14—Specific host cells or culture conditions, e.g. components, pH or temperature
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- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
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- C07K2317/569—Single domain, e.g. dAb, sdAb, VHH, VNAR or nanobody®
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- C07K2319/00—Fusion polypeptide
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- C07K2319/00—Fusion polypeptide
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261651933P | 2012-05-25 | 2012-05-25 | |
| US61/651,933 | 2012-05-25 | ||
| US201261696612P | 2012-09-04 | 2012-09-04 | |
| US61/696,612 | 2012-09-04 | ||
| PCT/US2013/040766 WO2013176916A1 (en) | 2012-05-25 | 2013-05-13 | Use of pre t alpha or functional variant thereof for expanding tcr alpha deficient t cells |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017163088A Division JP6655049B2 (ja) | 2012-05-25 | 2017-08-28 | Tcrアルファ欠損t細胞を増殖させるためのプレtアルファまたはその機能性変種の使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015525065A JP2015525065A (ja) | 2015-09-03 |
| JP2015525065A5 JP2015525065A5 (enExample) | 2016-06-30 |
| JP6463672B2 true JP6463672B2 (ja) | 2019-02-06 |
Family
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Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015514051A Active JP6463672B2 (ja) | 2012-05-25 | 2013-05-13 | Tcrアルファ欠損t細胞を増殖させるためのプレtアルファまたはその機能性変種の使用 |
| JP2015514050A Active JP6463671B2 (ja) | 2012-05-25 | 2013-05-13 | 免疫療法のための同種および免疫抑制耐性t細胞を操作するための方法 |
| JP2017163088A Active JP6655049B2 (ja) | 2012-05-25 | 2017-08-28 | Tcrアルファ欠損t細胞を増殖させるためのプレtアルファまたはその機能性変種の使用 |
| JP2018137466A Active JP7257749B2 (ja) | 2012-05-25 | 2018-07-23 | 免疫療法のための同種および免疫抑制耐性t細胞を操作するための方法 |
| JP2019000204A Active JP6991167B2 (ja) | 2012-05-25 | 2019-01-04 | 免疫療法のための同種および免疫抑制耐性t細胞を操作するための方法 |
Family Applications After (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015514050A Active JP6463671B2 (ja) | 2012-05-25 | 2013-05-13 | 免疫療法のための同種および免疫抑制耐性t細胞を操作するための方法 |
| JP2017163088A Active JP6655049B2 (ja) | 2012-05-25 | 2017-08-28 | Tcrアルファ欠損t細胞を増殖させるためのプレtアルファまたはその機能性変種の使用 |
| JP2018137466A Active JP7257749B2 (ja) | 2012-05-25 | 2018-07-23 | 免疫療法のための同種および免疫抑制耐性t細胞を操作するための方法 |
| JP2019000204A Active JP6991167B2 (ja) | 2012-05-25 | 2019-01-04 | 免疫療法のための同種および免疫抑制耐性t細胞を操作するための方法 |
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| PT (2) | PT3473707T (enExample) |
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| UA (1) | UA118652C2 (enExample) |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2016539117A (ja) * | 2013-11-22 | 2016-12-15 | セレクティスCellectis | 平均化された効力を持つ同種異系t細胞のバッチを生成するための方法 |
Families Citing this family (437)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9273283B2 (en) * | 2009-10-29 | 2016-03-01 | The Trustees Of Dartmouth College | Method of producing T cell receptor-deficient T cells expressing a chimeric receptor |
| WO2013066438A2 (en) | 2011-07-22 | 2013-05-10 | President And Fellows Of Harvard College | Evaluation and improvement of nuclease cleavage specificity |
| US10704021B2 (en) | 2012-03-15 | 2020-07-07 | Flodesign Sonics, Inc. | Acoustic perfusion devices |
| US9950282B2 (en) | 2012-03-15 | 2018-04-24 | Flodesign Sonics, Inc. | Electronic configuration and control for acoustic standing wave generation |
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| JP2016539117A (ja) * | 2013-11-22 | 2016-12-15 | セレクティスCellectis | 平均化された効力を持つ同種異系t細胞のバッチを生成するための方法 |
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Free format text: JAPANESE INTERMEDIATE CODE: R250 |