|
US3941790A
(en)
|
1967-07-03 |
1976-03-02 |
National Research Development Corporation |
Bis diketopiperazines
|
|
BE765030A
(fr)
|
1970-04-02 |
1971-08-16 |
Snam Progetti |
Composes contenant un noyau de dicetopiperazine et leur procedede fabrication
|
|
GB1353304A
(en)
|
1971-03-30 |
1974-05-15 |
Sagami Chem Res |
Process for production of diketopiperazine dihydroxamates and intermediate therefor
|
|
US4006261A
(en)
|
1973-09-28 |
1977-02-01 |
Firmenich S.A. |
Flavoring with mixtures of theobromine and cyclic dipeptides
|
|
US3928330A
(en)
|
1973-12-19 |
1975-12-23 |
Ciba Geigy Corp |
Substituted piperazinedione carboxylic acids and metal salts thereof
|
|
GB1459488A
(en)
|
1974-03-19 |
1976-12-22 |
Wyeth John & Brother Ltd |
Piperazinedione derivatives
|
|
US4088649A
(en)
|
1975-07-02 |
1978-05-09 |
Firmenich S.A. |
Process for preparing a diketo-piperazine
|
|
JPS5225019A
(en)
|
1975-08-19 |
1977-02-24 |
New Zealand Inventions Dev |
Production of serum albumin
|
|
US4205057A
(en)
|
1978-01-17 |
1980-05-27 |
Government Of The United States |
Cerebrospinal fluid protein fragments
|
|
DE2940654A1
(de)
|
1979-10-06 |
1981-04-16 |
Bayer Ag, 5090 Leverkusen |
Dimeres keten der 1,2,,-triazol-3-carbonsaeure
|
|
US4289759A
(en)
|
1980-06-23 |
1981-09-15 |
Ortho Pharmaceutical Corporation |
Immunoregulatory diketopiperazine compounds
|
|
US4331595A
(en)
|
1980-06-23 |
1982-05-25 |
Ortho Pharmaceutical Corporation |
Immunoregulatory diketopiperazine compounds
|
|
JPS5836225U
(ja)
|
1981-08-31 |
1983-03-09 |
株式会社東芝 |
金属製平パレツト
|
|
JPS5973574A
(ja)
|
1982-10-21 |
1984-04-25 |
Grelan Pharmaceut Co Ltd |
環状ジペプチド類
|
|
US4694061A
(en)
|
1983-10-12 |
1987-09-15 |
Ciba-Geigy Corporation |
Radiation-sensitive polycondensates, processes for their preparation coated material and its use
|
|
NZ212051A
(en)
|
1984-05-18 |
1988-10-28 |
Univ Australian |
Immune response suppression; certain epipolythio- dioxopiperazine derivatives and their preparation
|
|
US4806538A
(en)
|
1984-11-02 |
1989-02-21 |
Fujisawa Pharmaceutical Co., Ltd. |
Piperazine compound as PAF-antagonist
|
|
JPS61112060A
(ja)
|
1984-11-02 |
1986-05-30 |
Fujisawa Pharmaceut Co Ltd |
ピペラジン化合物
|
|
CS254868B1
(cs)
|
1985-06-11 |
1988-02-15 |
Jiri Vanzura |
Způsob výroby cyklických dipeptidů
|
|
JPS6236331A
(ja)
|
1985-08-12 |
1987-02-17 |
Kenji Suzuki |
抗感染症剤ならびに免疫賦活剤
|
|
US4771056A
(en)
|
1985-08-29 |
1988-09-13 |
Roman Rozencwaig |
Method of medical treatment with serotonin antagonists
|
|
US4661500A
(en)
|
1985-08-29 |
1987-04-28 |
Roman Rozencwaig |
Method of medical treatment with serotonin antagonists
|
|
US5047401A
(en)
|
1985-09-09 |
1991-09-10 |
Board Of Regents, The University Of Texas System |
Use of dipeptide alkyl esters to treat GVHD
|
|
US4694081A
(en)
|
1985-09-23 |
1987-09-15 |
Monsanto Company |
Process to prepare 2,5-diketopiperazines
|
|
PT83613B
(en)
|
1985-10-28 |
1988-11-21 |
Lilly Co Eli |
Process for the selective chemical removal of a protein amino-terminal residue
|
|
JPS63290868A
(ja)
|
1987-05-22 |
1988-11-28 |
Fujisawa Pharmaceut Co Ltd |
ジケトピペラジン誘導体およびその塩類
|
|
JPS6413075A
(en)
|
1987-07-03 |
1989-01-17 |
Nippon Chemiphar Co |
Production of 2, 5-piperazinedione derivative
|
|
US5512544A
(en)
|
1987-09-13 |
1996-04-30 |
Yeda Research And Development Co. Ltd. |
Pharmaceutical compositions comprising an anticytokine
|
|
US4992552A
(en)
|
1988-08-31 |
1991-02-12 |
Eastman Kodak Company |
Process for preparation of amino acids
|
|
US5144073A
(en)
|
1988-08-31 |
1992-09-01 |
Hubbs John C |
Process for preparation of dipeptides
|
|
JP2001055340A
(ja)
|
1988-10-31 |
2001-02-27 |
Welfide Corp |
アルブミン製剤の製造方法
|
|
US5238938A
(en)
|
1989-02-10 |
1993-08-24 |
Otsuka Pharmaceutical Co., Ltd. |
Indole derivatives
|
|
DE3906952A1
(de)
|
1989-03-04 |
1990-09-06 |
Boehringer Mannheim Gmbh |
(3-(c(pfeil abwaerts)1(pfeil abwaerts)(pfeil abwaerts)6(pfeil abwaerts)-c(pfeil abwaerts)1(pfeil abwaerts)(pfeil abwaerts)8(pfeil abwaerts))alkansulfinyl- und sulfonyl-2-methoxymethyl-propyl)-(2-trimethylammonio-ethyl) phosphate, verfahren zu deren herstellung diese verbindungen enthaltende arzneimittel
|
|
US5902790A
(en)
|
1995-10-03 |
1999-05-11 |
Cytran, Inc. |
Pharmaceutical angiostatic dipeptide compositions and method of use thereof
|
|
ATE120777T1
(de)
|
1989-10-13 |
1995-04-15 |
Phobos Nv |
Verfahren zur kontinuierlichen herstellung von hochmolekularen polyester-harzen.
|
|
JPH03176478A
(ja)
|
1989-12-05 |
1991-07-31 |
Snow Brand Milk Prod Co Ltd |
新規なジケトピペラジン誘導体及びこれを有効成分とする免疫抑制剤
|
|
DK0478729T3
(da)
|
1990-03-15 |
1996-09-16 |
Nutrasweet Co |
Fremgangsmåde til fremstilling af aspartam ud fra et diketopiperazin, og hidtil ukendte mellemprodukter og derivater dertil
|
|
US6180616B1
(en)
|
1990-05-10 |
2001-01-30 |
Atsuo F. Fukunaga |
Use of purine receptor agonists to alleviate or normalize physiopathologically excited sensory nerve function
|
|
US6331318B1
(en)
|
1994-09-30 |
2001-12-18 |
Emisphere Technologies Inc. |
Carbon-substituted diketopiperazine delivery systems
|
|
US5693338A
(en)
|
1994-09-29 |
1997-12-02 |
Emisphere Technologies, Inc. |
Diketopiperazine-based delivery systems
|
|
US5578323A
(en)
|
1992-06-15 |
1996-11-26 |
Emisphere Technologies, Inc. |
Proteinoid carriers and methods for preparation and use thereof
|
|
US6099856A
(en)
|
1992-06-15 |
2000-08-08 |
Emisphere Technologies, Inc. |
Active agent transport systems
|
|
GB9022543D0
(en)
|
1990-10-17 |
1990-11-28 |
Wellcome Found |
Antibody production
|
|
CA2095539A1
(en)
|
1990-11-14 |
1992-05-15 |
Robert D. Cook |
Diagnosis and treatment of multiple sclerosis
|
|
US5776892A
(en)
|
1990-12-21 |
1998-07-07 |
Curative Health Services, Inc. |
Anti-inflammatory peptides
|
|
JPH04234374A
(ja)
|
1990-12-27 |
1992-08-24 |
Ajinomoto Co Inc |
ジケトピペラジン誘導体の製造方法
|
|
GB9102997D0
(en)
|
1991-02-13 |
1991-03-27 |
Pfizer Ltd |
Therapeutic agents
|
|
US5543503A
(en)
|
1991-03-29 |
1996-08-06 |
Genentech Inc. |
Antibodies to human IL-8 type A receptor
|
|
US5538993A
(en)
|
1991-09-12 |
1996-07-23 |
Yissum Research Development Company |
Certain tetrahydrocannabinol-7-oic acid derivatives
|
|
DE69230500D1
(de)
|
1991-10-28 |
2000-02-03 |
Cytran Ltd |
Pharmazeutische Dipeptid Zusammensetzungen und Verwendungsmethoden.
|
|
JPH05244982A
(ja)
|
1991-12-06 |
1993-09-24 |
Sumitomo Chem Co Ltd |
擬人化ｂ−ｂ１０
|
|
JPH05163148A
(ja)
|
1991-12-18 |
1993-06-29 |
Kanebo Ltd |
抗腫瘍剤
|
|
GB9200210D0
(en)
|
1992-01-07 |
1992-02-26 |
British Bio Technology |
Compounds
|
|
US5352461A
(en)
|
1992-03-11 |
1994-10-04 |
Pharmaceutical Discovery Corporation |
Self assembling diketopiperazine drug delivery system
|
|
JP3176478B2
(ja)
|
1992-05-29 |
2001-06-18 |
いすゞ自動車株式会社 |
居眠り運転防止装置
|
|
US5418218A
(en)
|
1992-07-10 |
1995-05-23 |
The University Of Maryland At Baltimore |
Histidyl-proline diketopiperazine (cyclo his-pro) a cns-active pharmacologic agent
|
|
US5358938A
(en)
|
1992-07-13 |
1994-10-25 |
Cytomed, Inc. |
Compounds and methods for the treatment of disorders mediated by platelet activating factor or products of 5-lipoxygenase
|
|
US5648486A
(en)
|
1992-07-13 |
1997-07-15 |
Cytomed, Inc. |
Compounds and methods for the treatment of inflammatory and immune disorders
|
|
US5434151A
(en)
|
1992-08-24 |
1995-07-18 |
Cytomed, Inc. |
Compounds and methods for the treatment of disorders mediated by platelet activating factor or products of 5-lipoxygenase
|
|
US5463083A
(en)
|
1992-07-13 |
1995-10-31 |
Cytomed, Inc. |
Compounds and methods for the treatment of cardiovascular, inflammatory and immune disorders
|
|
GB9217331D0
(en)
|
1992-08-14 |
1992-09-30 |
Xenova Ltd |
Pharmaceutical compounds
|
|
WO1994004537A2
(en)
|
1992-08-20 |
1994-03-03 |
Cytomed, Inc. |
Dual functional anti-inflammatory and immunosuppressive agents
|
|
US5728553A
(en)
|
1992-09-23 |
1998-03-17 |
Delta Biotechnology Limited |
High purity albumin and method of producing
|
|
EP0674661B1
(en)
|
1992-12-18 |
2003-07-02 |
Molecular Rx., Inc. |
Assay and treatment for demyelinating diseases such as multiple sclerosis
|
|
ES2068742B1
(es)
|
1993-02-11 |
1995-11-16 |
Uriach & Cia Sa J |
Nuevos derivados de piridinio.
|
|
AU6359594A
(en)
|
1993-03-04 |
1994-09-26 |
Cytoven International N.V. |
Pharmaceutical tryptophan containing dipeptide compositions and methods of use thereof
|
|
US6107050A
(en)
|
1993-05-03 |
2000-08-22 |
The United States Of America As Represented By The Department Of Health And Human Services |
Diagnostic test for alzheimers disease
|
|
US5523226A
(en)
*
|
1993-05-14 |
1996-06-04 |
Biotechnology Research And Development Corp. |
Transgenic swine compositions and methods
|
|
CA2167805A1
(en)
|
1993-07-23 |
1995-02-02 |
L. David Tomei |
Methods of treating apoptosis and associated conditions
|
|
GB9324872D0
(en)
|
1993-12-03 |
1994-01-19 |
Univ Pasteur |
Pharmaceutical compounds
|
|
IL112627A0
(en)
|
1994-02-14 |
1995-05-26 |
Xenova Ltd |
Diketopiperazines, their preparation and pharmaceutical or veterinary compositions containing them
|
|
JP2921731B2
(ja)
|
1994-03-10 |
1999-07-19 |
日清製油株式会社 |
有機溶媒または油脂類のゲル化剤
|
|
FR2717484A1
(fr)
|
1994-03-16 |
1995-09-22 |
Pf Medicament |
Nouveaux composés pseudo-bis-peptidiques analogues de la CCK, leur procédé de préparation, leur utilisation à titre de médicament et les compositions pharmaceutiques les comprenant .
|
|
GB9410387D0
(en)
|
1994-05-24 |
1994-07-13 |
Xenova Ltd |
Pharmaceutical compounds
|
|
US5550132A
(en)
|
1994-06-22 |
1996-08-27 |
University Of North Carolina |
Hydroxyalkylammonium-pyrimidines or purines and nucleoside derivatives, useful as inhibitors of inflammatory cytokines
|
|
US5990112A
(en)
|
1996-06-18 |
1999-11-23 |
Affymax Technologies N.V. |
Inhibitors of metalloproteases pharmaceutical compositions comprising same and methods of their use
|
|
AU2871195A
(en)
|
1994-06-23 |
1996-01-19 |
Affymax Technologies N.V. |
Methods for the synthesis of diketopiperazines
|
|
US5817751A
(en)
|
1994-06-23 |
1998-10-06 |
Affymax Technologies N.V. |
Method for synthesis of diketopiperazine and diketomorpholine derivatives
|
|
US5750565A
(en)
|
1995-05-25 |
1998-05-12 |
Cytomed, Inc. |
Compounds and methods for the treatment of cardiovascular, inflammatory and immune disorders
|
|
CN1151125C
(zh)
|
1994-06-27 |
2004-05-26 |
千年药品公司 |
治疗心血管疾病,炎症和免疫疾病的化合物和方法
|
|
US5792776A
(en)
|
1994-06-27 |
1998-08-11 |
Cytomed, Inc., |
Compounds and methods for the treatment of cardiovascular, inflammatory and immune disorders
|
|
US5703093A
(en)
|
1995-05-31 |
1997-12-30 |
Cytomed, Inc. |
Compounds and methods for the treatment of cardiovascular, inflammatory and immune disorders
|
|
US5843950A
(en)
|
1994-07-29 |
1998-12-01 |
Nikken Chemicals Co., Ltd. |
1,4-dihydropyridine compound and pharmaceutical composition containing the same
|
|
US5561115A
(en)
|
1994-08-10 |
1996-10-01 |
Bayer Corporation |
Low temperature albumin fractionation using sodium caprylate as a partitioning agent
|
|
NZ293642A
(en)
|
1994-10-05 |
1998-10-28 |
Cari Loder |
Prevention or treatment of nerve damage caused by multiple sclerosis and other demyelinating conditions with a tri- or tetracyclic antidepressant or a monoamine oxidase inhibitor and a neurotransmitter-inducer
|
|
ES2087038B1
(es)
|
1994-11-07 |
1997-03-16 |
Uriach & Cia Sa J |
Nuevas piperidinas con actividad antagonista del paf.
|
|
CZ282794A3
(en)
|
1994-11-16 |
1996-04-17 |
Galena |
Pentapeptidic precursors of biologically active cyclic dipeptides
|
|
AU691361B2
(en)
|
1994-12-01 |
1998-05-14 |
Toyama Chemical Co. Ltd. |
Novel 2,3-diketopiperazine derivative or salt thereof
|
|
JP3634891B2
(ja)
|
1995-04-06 |
2005-03-30 |
株式会社海洋バイオテクノロジー研究所 |
キチナーゼ阻害物質
|
|
US6096871A
(en)
|
1995-04-14 |
2000-08-01 |
Genentech, Inc. |
Polypeptides altered to contain an epitope from the Fc region of an IgG molecule for increased half-life
|
|
JPH11508583A
(ja)
|
1995-07-06 |
1999-07-27 |
ゼネカ・リミテッド |
ペプチド系のフィブロネクチン阻害薬
|
|
US5811241A
(en)
|
1995-09-13 |
1998-09-22 |
Cortech, Inc. |
Method for preparing and identifying N-substitued 1,4-piperazines and N-substituted 1,4-piperazinediones
|
|
US5665714A
(en)
|
1995-12-07 |
1997-09-09 |
Clarion Pharmaceuticals Inc. |
N-substituted glycerophosphoethanolamines
|
|
US6060452A
(en)
|
1996-03-13 |
2000-05-09 |
Cytran, Inc. |
Analogs of L-Glu-L-Trp having pharmacological activity
|
|
US6541224B2
(en)
|
1996-03-14 |
2003-04-01 |
Human Genome Sciences, Inc. |
Tumor necrosis factor delta polypeptides
|
|
EP0891349A4
(en)
|
1996-04-03 |
2001-01-24 |
Merck & Co Inc |
INHIBITORS OF FARNESYL PROTEIN TRANSFERASE
|
|
CN1215404A
(zh)
|
1996-04-03 |
1999-04-28 |
佩普里瑟奇公司 |
非树状骨架肽载体
|
|
US5919785A
(en)
|
1996-04-03 |
1999-07-06 |
Merck & Co., Inc. |
Inhibitors of farnesyl-protein transferase
|
|
US6262119B1
(en)
|
1996-04-12 |
2001-07-17 |
Peptide Technology Limited |
Methods of treating immunopathologies using polyunsaturated fatty acids
|
|
US5932579A
(en)
|
1996-06-18 |
1999-08-03 |
Affymax Technologies N.V. |
Collagenase-1 and stromelysin-1 inhibitors, pharmaceutical compositions comprising same and methods of their use
|
|
US5985581A
(en)
|
1996-07-25 |
1999-11-16 |
The Mclean Hospital Corporation |
Use of presenilin-1 for diagnosis of alzheimers disease
|
|
WO1998009968A1
(en)
|
1996-09-09 |
1998-03-12 |
Novartis Animal Health Australasia Pty. Limited |
Terpenylated diketopiperazines, (drimentines)
|
|
NZ335544A
(en)
|
1996-10-04 |
2001-08-31 |
Neuronz Ltd |
Use of GPE (tripeptide or dipeptide) in form of Gly-Pro-Glu or Gly-Pro or Pro-Glu as a neuromodulator
|
|
RU2125728C1
(ru)
|
1996-10-10 |
1999-01-27 |
Пермская государственная медицинская академия |
Способ иммунодиагностики рассеянного склероза
|
|
EP0835660A1
(en)
|
1996-10-14 |
1998-04-15 |
Gaston Edmond Filomena Merckx |
Products containing methylcobalamin for the treatment of multiple sclerosis or other demyelinating conditions
|
|
US6441172B1
(en)
|
1996-11-07 |
2002-08-27 |
Torrey Pines Institute For Molecular Studies |
Diketodiazacyclic compounds, diazacyclic compounds and combinatorial libraries thereof
|
|
US5932112A
(en)
|
1996-11-27 |
1999-08-03 |
Browning Transport Management, Inc. |
Method and apparatus for killing microorganisms in ship ballast water
|
|
RU2112242C1
(ru)
|
1996-12-09 |
1998-05-27 |
Пермская государственная медицинская академия |
Способ диагностики рассеянного склероза
|
|
JPH10226615A
(ja)
|
1997-02-18 |
1998-08-25 |
Pola Chem Ind Inc |
アスパラギン酸フェニルアラニン環状ジペプタイド誘導体を含有する組成物
|
|
JPH10245315A
(ja)
|
1997-03-05 |
1998-09-14 |
Pola Chem Ind Inc |
シクロジペプタイド誘導体を含有する組成物
|
|
US6306909B1
(en)
|
1997-03-12 |
2001-10-23 |
Queen's University At Kingston |
Anti-epileptogenic agents
|
|
AU6465798A
(en)
|
1997-03-14 |
1998-09-29 |
Neuromark |
Diagnosing neurologic disorders
|
|
US6265535B1
(en)
|
1997-05-30 |
2001-07-24 |
The Trustees Of The University Of Pennsylvania |
Peptides and peptide analogues designed from binding sites of tumor necrosis factor receptor superfamily and their uses
|
|
RU2128840C1
(ru)
|
1997-06-16 |
1999-04-10 |
Пермская государственная медицинская академия |
Способ диагностики рассеянного склероза
|
|
US6222029B1
(en)
|
1997-08-01 |
2001-04-24 |
Genset |
5′ ESTs for secreted proteins expressed in brain
|
|
US5834032A
(en)
|
1997-08-11 |
1998-11-10 |
Song; Moon K. |
Compositions and methods for treating diabetes
|
|
US7202279B1
(en)
|
1998-02-11 |
2007-04-10 |
Georgetown University |
Cyclic dipeptides and azetidinone compounds and their use in treating CNS injury and neurodegenerative disorders
|
|
EP0939124A3
(en)
|
1998-02-24 |
2001-03-21 |
Smithkline Beecham Plc |
MGBP1 sequences
|
|
AU3370099A
(en)
|
1998-03-31 |
1999-10-18 |
Mayo Foundation For Medical Education And Research |
Use of platelet activating factor (paf) inhibitors to inhibit il-5 induced eosinophil activation or degranulation
|
|
EP1067951A2
(en)
|
1998-04-03 |
2001-01-17 |
Cytran Ltd. |
Use of l-glu-l-trp in the treatment of hiv infection
|
|
AU3467099A
(en)
|
1998-04-03 |
1999-10-25 |
Cytran Ltd. |
Methods for production of therapeutic cytokines
|
|
AU767241B2
(en)
|
1998-09-14 |
2003-11-06 |
Qiang Xu |
Immunosuppressive agents
|
|
US6492179B1
(en)
|
1998-10-02 |
2002-12-10 |
Ischemia Techologies, Inc. |
Test for rapid evaluation of ischemic states and kit
|
|
US6461875B1
(en)
|
1998-10-02 |
2002-10-08 |
Ischemia Technologies, Inc. |
Test for rapid evaluation of ischemic states and kit
|
|
US6475743B1
(en)
|
1998-10-02 |
2002-11-05 |
Ischemia Technologies, Inc. |
Marker useful for detection and measurement of free radical damage and method
|
|
WO2000020840A1
(en)
|
1998-10-02 |
2000-04-13 |
Ischemia Technologies, Inc. |
Tests for the rapid evaluation of ischemic states and kits
|
|
DE69939121D1
(de)
|
1998-10-02 |
2008-08-28 |
Ischemia Tech Inc |
Verfahren und materialien zum nachweis und zur messung von durch freie radikale verursachten schäden
|
|
DE19847690A1
(de)
|
1998-10-15 |
2000-04-20 |
Brahms Diagnostica Gmbh |
Verfahren und Substanzen für die Diagnose und Therapie von Sepsis und sepsisähnlichen systemischen Infektionen
|
|
US7026322B2
(en)
|
1998-11-12 |
2006-04-11 |
Nereus Pharmaceuticals, Inc. |
Phenylahistin and the phenylahistin analogs, a new class of anti-tumor compounds
|
|
US6358957B1
(en)
|
1998-11-12 |
2002-03-19 |
Nereus Pharmaceuticals, Inc. |
Phenylahistin and the phenylahistin analogs, a new class of anti-tumor compounds
|
|
WO2000043000A1
(en)
|
1999-01-20 |
2000-07-27 |
Kyowa Hakko Kogyo Co., Ltd. |
Proteasome inhibitors
|
|
US6248363B1
(en)
|
1999-11-23 |
2001-06-19 |
Lipocine, Inc. |
Solid carriers for improved delivery of active ingredients in pharmaceutical compositions
|
|
EP1166117A2
(en)
|
1999-03-19 |
2002-01-02 |
Vanderbilt University |
Diagnosis and treatment of multiple sclerosis
|
|
US6090780A
(en)
|
1999-04-07 |
2000-07-18 |
Chandon Prasad |
Histidyl-proline diketopiperazine and method of use
|
|
US6689765B2
(en)
|
1999-05-04 |
2004-02-10 |
Schering Corporation |
Piperazine derivatives useful as CCR5 antagonists
|
|
JP2000327575A
(ja)
|
1999-05-26 |
2000-11-28 |
Teika Seiyaku Kk |
ジケトピペラジン誘導体含有炎症疾患治療剤および新規なジケトピペラジン誘導体
|
|
DE19937721A1
(de)
|
1999-08-10 |
2001-02-15 |
Max Planck Gesellschaft |
Neue Diketopiperazine
|
|
WO2001034586A2
(en)
|
1999-11-12 |
2001-05-17 |
Wyeth |
Branched adamantyl and noradamantyl aryl- and aralkylpiperazines with serotonin 5-ht1a activity
|
|
WO2001036351A2
(en)
|
1999-11-19 |
2001-05-25 |
Corvas International, Inc. |
Plasminogen activator inhibitor antagonists related applications
|
|
US20050096323A1
(en)
|
1999-11-30 |
2005-05-05 |
Novoscience Pharma Inc. |
Diketopiperazine derivatives to inhibit thrombin
|
|
US7163671B2
(en)
|
2000-02-29 |
2007-01-16 |
Chugai Seiyaku Kabushiki Kaisha |
Long-term stabilized formulations
|
|
DE10019879A1
(de)
|
2000-04-20 |
2001-10-25 |
Degussa |
Verfahren zur Herstellung von 2,5-Diketopiperazinen, neue 2,5-Diketopiperazine und deren Verwendung
|
|
US7288545B2
(en)
|
2000-05-09 |
2007-10-30 |
Angiorx Corporation |
Piperazinedione compounds
|
|
JP5101781B2
(ja)
|
2000-05-09 |
2012-12-19 |
アンギオアールエックス コーポレイション |
ピペラジンジオン化合物
|
|
DE10026998A1
(de)
|
2000-05-31 |
2001-12-13 |
Fresenius Kabi De Gmbh |
Verfahren zur Herstellung einer kosmetischen Zusammensetzung, die humanes Serum Albumin umfasst, welches aus transgenen nicht-menschlichen Säugern erhalten wurde
|
|
CA2411010A1
(en)
|
2000-06-08 |
2001-12-13 |
Lilly Icos Llc |
Tetracyclic diketopiperazine compounds as pdev inhibitors
|
|
EP1311277A4
(en)
|
2000-07-18 |
2004-08-25 |
Joslin Diabetes Center Inc |
METHODS OF FIBROSIS MODULATION
|
|
CZ20002680A3
(cs)
|
2000-07-21 |
2002-03-13 |
Ev®En Ing. Csc. Kasafírek |
Cyklické alkylthiopeptidy
|
|
CZ20002681A3
(cs)
|
2000-07-21 |
2002-03-13 |
Ev®En Ing. Csc. Kasafírek |
Cyklické tyrosinové dipeptidy
|
|
JP5048201B2
(ja)
*
|
2000-08-04 |
2012-10-17 |
ディーエムアイ バイオサイエンシズ インコーポレイテッド |
ジケトピペラジン類の使用方法とジケトピペラジン類を含む組成物
|
|
US6967202B2
(en)
|
2000-08-04 |
2005-11-22 |
Dmi Biosciences, Inc. |
Method of synthesizing diketopiperazines
|
|
US20070208087A1
(en)
|
2001-11-02 |
2007-09-06 |
Sanders Virginia J |
Compounds, compositions and methods for the treatment of inflammatory diseases
|
|
AU2001297611A1
(en)
|
2000-12-29 |
2002-08-19 |
Celltech R And D, Inc. |
Pharmaceutical uses and synthesis of diketopiperazines
|
|
GB2372740A
(en)
|
2001-01-17 |
2002-09-04 |
Xenova Ltd |
Diketopiperazines
|
|
WO2002059604A2
(en)
|
2001-01-26 |
2002-08-01 |
Oxford Glycosciences (Uk) Ltd |
Diagnosis and treatment of multiple sclerosis
|
|
DE60214701T2
(de)
|
2001-04-13 |
2007-09-13 |
Vertex Pharmaceuticals Inc., Cambridge |
Inhibitoren von c-jun-n-terminalen-kinasen (jnk) und anderen proteinkinasen
|
|
CA2446380A1
(en)
|
2001-05-08 |
2002-11-14 |
Yale University |
Proteomimetic compounds and methods
|
|
US7368421B2
(en)
|
2001-06-27 |
2008-05-06 |
Probiodrug Ag |
Use of dipeptidyl peptidase IV inhibitors in the treatment of multiple sclerosis
|
|
WO2003032809A2
(en)
|
2001-10-15 |
2003-04-24 |
The Medstar Research Institute |
Modulation of akt-dependent response to prevent restenosis
|
|
US20040063654A1
(en)
|
2001-11-02 |
2004-04-01 |
Davis Mark E. |
Methods and compositions for therapeutic use of RNA interference
|
|
JP2005527639A
(ja)
|
2001-11-02 |
2005-09-15 |
インサート セラピューティクス インコーポレイテッド |
Ｒｎａ干渉の治療的利用のための方法及び組成物
|
|
GB0128108D0
(en)
|
2001-11-23 |
2002-01-16 |
Astrazeneca Ab |
Therapeutic use
|
|
DE60239072D1
(de)
|
2001-12-27 |
2011-03-10 |
Ajinomoto Kk |
Verfahren zur herstellung von glutaminsäurederivaten
|
|
AU2002358162A1
(en)
|
2002-01-18 |
2003-07-30 |
Unilever Plc |
Cosmetic compositions comprising a cyclodipeptide compound
|
|
EP1497268A4
(en)
|
2002-04-05 |
2006-01-18 |
Nitromed Inc |
NITROGEN OXIDE DISPENSER, COMPOSITIONS AND METHOD OF USE
|
|
ES2204294B2
(es)
|
2002-07-02 |
2005-02-01 |
Universidade De Santiago De Compostela |
Nuevos antibioticos activos frente al vibrio anguillarum y sus aplicaciones en cultivos de peces, crustaceos, moluscos y otras actividades de acuicultura.
|
|
US20080260838A1
(en)
|
2003-08-01 |
2008-10-23 |
Mannkind Corporation |
Glucagon-like peptide 1 (glp-1) pharmaceutical formulations
|
|
US20040038865A1
(en)
|
2002-08-01 |
2004-02-26 |
Mannkind Corporation |
Cell transport compositions and uses thereof
|
|
AU2003302721B2
(en)
|
2002-08-02 |
2009-10-08 |
Beyondspring Pharmaceuticals, Inc. |
Dehydrophenylahistins and analogs thereof and the synthesis of dehydrophenylahistins and analogs thereof
|
|
US7919497B2
(en)
|
2002-08-02 |
2011-04-05 |
Nereus Pharmaceuticals, Inc. |
Analogs of dehydrophenylahistins and their therapeutic use
|
|
KR20050042146A
(ko)
|
2002-08-06 |
2005-05-04 |
아플라겐 게엠베하 |
결합 분자
|
|
DE10238144A1
(de)
|
2002-08-15 |
2004-02-26 |
Basf Ag |
Verwendung von Diketopiperazin-Derivaten als photostabile UV-Filter in kosmetischen und pharmazeutischen Zubereitungen
|
|
US7378403B2
(en)
|
2002-09-03 |
2008-05-27 |
The United States Of America As Represented By The Department Of Health And Human Services |
Akt inhibitors, pharmaceutical compositions, and uses thereof
|
|
DK1571970T3
(da)
|
2002-10-02 |
2011-11-28 |
Dmi Biosciences Inc |
Diagnose og monitorering af sygdomme
|
|
US7196169B2
(en)
|
2002-10-11 |
2007-03-27 |
Queen's University At Kingston |
Isolated post-translationally modified mammalian proteins for monitoring and diagnosing muscle damage
|
|
AU2003281978A1
(en)
|
2002-11-22 |
2004-06-18 |
Boehringer Ingelheim International Gmbh |
2,5-diketopiperazines for the treatment of obesity
|
|
CN102210852B
(zh)
|
2003-05-15 |
2016-10-19 |
安皮奥制药股份有限公司 |
T-细胞介导的疾病的治疗
|
|
CN1791420A
(zh)
*
|
2003-05-15 |
2006-06-21 |
Dmi生物科学公司 |
T－细胞介导的疾病的治疗
|
|
KR20060037409A
(ko)
|
2003-07-30 |
2006-05-03 |
제논 파마슈티칼스 인크. |
피페라진 유도체 및 그의 치료제로서의 용도
|
|
EP1664050B1
(en)
|
2003-09-03 |
2015-12-09 |
Neuren Pharmaceuticals Limited |
Neuroprotective bicyclic compounds and pharmaceutical compositions containing them
|
|
JP2008505084A
(ja)
|
2004-06-29 |
2008-02-21 |
アムゲン インコーポレイティッド |
フラノピリミジン
|
|
JP4970260B2
(ja)
|
2004-08-20 |
2012-07-04 |
プロメティック バイオサイエンシズ，リミテッド |
親和性クロマトグラフィーによるタンパク質の逐次的単離および精製スキーム
|
|
HUE025151T2
(en)
|
2004-08-23 |
2016-01-28 |
Mannkind Corp |
Diceto-piperazine salts for drug delivery
|
|
AU2006216998B2
(en)
|
2005-02-14 |
2010-12-23 |
Merck Sharp & Dohme Corp. |
Inhibitors of Akt activity
|
|
CA2621595A1
(en)
|
2005-09-21 |
2007-04-12 |
Surmodics, Inc. |
Coatings and articles including natural biodegradable polysaccharides
|
|
CN104383546B
(zh)
|
2006-02-22 |
2021-03-02 |
曼金德公司 |
用于改善包含二酮哌嗪和活性剂的微粒的药物性质的方法
|
|
RU2409349C2
(ru)
|
2006-04-14 |
2011-01-20 |
Маннкайнд Корпорейшн |
Фармацевтические композиции, содержащие глюкагонподобный пептид(glp-1)
|
|
US20080017576A1
(en)
|
2006-06-15 |
2008-01-24 |
Rensselaer Polytechnic Institute |
Global model for optimizing crossflow microfiltration and ultrafiltration processes
|
|
AR061240A1
(es)
|
2006-06-20 |
2008-08-13 |
Lilly Co Eli |
Compuestos de de 4-isoquinolin-fenol,composiciones farmaceuticas que los contienen y su uso como agentes antineoplasicos y/o antivirales.
|
|
JP2009542813A
(ja)
|
2006-07-11 |
2009-12-03 |
ハルクネスス プハルマセウティカルス，インコーポレイテッド |
飽食因子を使用して肥満を治療する方法
|
|
US8231929B2
(en)
|
2006-11-09 |
2012-07-31 |
Cook Medical Technologies Llc |
Medical device coating process
|
|
CN101743007B
(zh)
|
2007-07-12 |
2015-04-08 |
南佛罗里达大学 |
具有抗肿瘤活性的akt/pkb抑制剂
|
|
US20090038416A1
(en)
|
2007-08-07 |
2009-02-12 |
Aleta Behrman Bonner |
System and method for biological sample collection and analyte detection
|
|
WO2009032651A1
(en)
|
2007-08-31 |
2009-03-12 |
Smithkline Beecham Corporation |
Inhibitors of akt activity
|
|
RU2481332C2
(ru)
|
2007-09-25 |
2013-05-10 |
Эбботт Лэборетриз |
Октагидропенталеновые соединения в качестве антагонистов хемокиновых рецепторов
|
|
US20090163936A1
(en)
|
2007-12-21 |
2009-06-25 |
Chunlin Yang |
Coated Tissue Engineering Scaffold
|
|
US20100042206A1
(en)
|
2008-03-04 |
2010-02-18 |
Icon Medical Corp. |
Bioabsorbable coatings for medical devices
|
|
WO2009114725A2
(en)
|
2008-03-12 |
2009-09-17 |
Children's Hospital Medical Center |
Mobilization of hematopoietic stem cells
|
|
JP5856843B2
(ja)
|
2008-05-27 |
2016-02-10 |
アンピオ ファーマシューティカルズ，インコーポレイテッド |
ジケトピペラジンを用いた医薬組成物
|
|
CN102272292A
(zh)
*
|
2008-09-22 |
2011-12-07 |
新加坡科技研究局 |
增加软骨形成祖细胞分化的方法
|
|
US8314106B2
(en)
|
2008-12-29 |
2012-11-20 |
Mannkind Corporation |
Substituted diketopiperazine analogs for use as drug delivery agents
|
|
MX2011009251A
(es)
|
2009-03-04 |
2011-11-18 |
Mannkind Corp |
Sistema mejorado de suministro de farmaco en polvo seco.
|
|
AU2010311332B2
(en)
|
2009-10-30 |
2015-04-23 |
Albumedix Ltd. |
Albumin variants
|
|
CN101914490B
(zh)
*
|
2010-08-13 |
2012-10-10 |
中国医科大学 |
一种人羊膜间充质干细胞无血清培养基及其培养方法
|
|
EP2613786A4
(en)
|
2010-09-07 |
2013-10-23 |
Dmi Acquisition Corp |
TREATMENT OF DISEASES
|
|
WO2012033789A2
(en)
|
2010-09-07 |
2012-03-15 |
Dmi Acquisition Corp. |
Treatment of diseases
|
|
US9487754B2
(en)
*
|
2010-10-01 |
2016-11-08 |
The Trustees Of Columbia University In The City Of New York |
Derivation of fibrochondrocytes from progenitor cells
|
|
WO2012174472A1
(en)
|
2011-06-17 |
2012-12-20 |
Mannkind Corporation |
High capacity diketopiperazine microparticles
|
|
JP2014530063A
(ja)
|
2011-10-10 |
2014-11-17 |
アンピオ ファーマシューティカルズ，インコーポレイテッド |
免疫寛容が高められた埋込み型医療用デバイス、ならびに製造方法および埋込み方法
|
|
PH12014500685B1
(en)
|
2011-10-10 |
2018-10-03 |
Ampio Pharmaceuticals Inc |
Treatment of degenerative joint disease
|
|
HK1198812A1
(en)
|
2011-10-28 |
2015-06-12 |
Ampio Pharmaceuticals, Inc. |
Treatment of rhinitis
|
|
JP3176478U
(ja)
|
2012-04-11 |
2012-06-21 |
ネイス株式会社 |
運動用エアートランポリン
|
|
WO2014121210A1
(en)
|
2013-02-01 |
2014-08-07 |
Ampio Pharmaceuticals, Inc. |
Methods for producing diketopiperazines and compositions containing diketopiperazines
|
|
CA2906864A1
(en)
|
2013-03-15 |
2014-09-18 |
Ampio Pharmaceuticals, Inc. |
Compositions for the mobilization, homing, expansion and differentiation of stem cells and methods of using the same
|
|
EP4066836A1
(en)
|
2014-08-18 |
2022-10-05 |
Ampio Pharmaceuticals, Inc. |
Treatment of joint conditions
|
|
EP3310375A4
(en)
|
2015-06-22 |
2019-02-20 |
Ampio Pharmaceuticals, Inc. |
USE OF LOW-MOLECULAR FRACTIONS OF HUMAN SERUMALBUMINE IN THE TREATMENT OF ILLNESSES
|