ATE401342T1 - Verfahren und materialien zum nachweis und zur messung von durch freie radikale verursachten schäden - Google Patents
Verfahren und materialien zum nachweis und zur messung von durch freie radikale verursachten schädenInfo
- Publication number
- ATE401342T1 ATE401342T1 AT99950055T AT99950055T ATE401342T1 AT E401342 T1 ATE401342 T1 AT E401342T1 AT 99950055 T AT99950055 T AT 99950055T AT 99950055 T AT99950055 T AT 99950055T AT E401342 T1 ATE401342 T1 AT E401342T1
- Authority
- AT
- Austria
- Prior art keywords
- albumin
- marker
- measurement
- detection
- detecting
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 4
- 102000009027 Albumins Human genes 0.000 abstract 6
- 108010088751 Albumins Proteins 0.000 abstract 6
- 239000003550 marker Substances 0.000 abstract 5
- 150000003254 radicals Chemical class 0.000 abstract 5
- 238000005259 measurement Methods 0.000 abstract 4
- 230000004075 alteration Effects 0.000 abstract 3
- 238000001514 detection method Methods 0.000 abstract 3
- 229910017052 cobalt Inorganic materials 0.000 abstract 2
- 239000010941 cobalt Substances 0.000 abstract 2
- GUTLYIVDDKVIGB-UHFFFAOYSA-N cobalt atom Chemical compound [Co] GUTLYIVDDKVIGB-UHFFFAOYSA-N 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 201000010099 disease Diseases 0.000 abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 abstract 1
- 102000007562 Serum Albumin Human genes 0.000 abstract 1
- 108010071390 Serum Albumin Proteins 0.000 abstract 1
- 238000004458 analytical method Methods 0.000 abstract 1
- 108010036999 aspartyl-alanyl-histidyl-lysine Proteins 0.000 abstract 1
- 239000008280 blood Substances 0.000 abstract 1
- 210000004369 blood Anatomy 0.000 abstract 1
- 125000003636 chemical group Chemical group 0.000 abstract 1
- 229940121657 clinical drug Drugs 0.000 abstract 1
- 229910052802 copper Inorganic materials 0.000 abstract 1
- 239000010949 copper Substances 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 238000003018 immunoassay Methods 0.000 abstract 1
- 238000010324 immunological assay Methods 0.000 abstract 1
- 239000002184 metal Substances 0.000 abstract 1
- 229910052751 metal Inorganic materials 0.000 abstract 1
- 229910021645 metal ion Inorganic materials 0.000 abstract 1
- 150000002739 metals Chemical class 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 238000011896 sensitive detection Methods 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/76—Albumins
- C07K14/765—Serum albumin, e.g. HSA
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6848—Methods of protein analysis involving mass spectrometry
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Food Science & Technology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Biophysics (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Computational Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Sampling And Sample Adjustment (AREA)
- Investigating And Analyzing Materials By Characteristic Methods (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10296298P | 1998-10-02 | 1998-10-02 | |
| US09/165,961 US6475743B1 (en) | 1998-10-02 | 1998-10-02 | Marker useful for detection and measurement of free radical damage and method |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE401342T1 true ATE401342T1 (de) | 2008-08-15 |
Family
ID=26799929
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99950055T ATE401342T1 (de) | 1998-10-02 | 1999-10-01 | Verfahren und materialien zum nachweis und zur messung von durch freie radikale verursachten schäden |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP1117686B1 (de) |
| AT (1) | ATE401342T1 (de) |
| AU (1) | AU6279399A (de) |
| DE (1) | DE69939121D1 (de) |
| WO (1) | WO2000020454A1 (de) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7282369B2 (en) | 1998-10-02 | 2007-10-16 | Ischemia Technologies, Inc. | Tests for the rapid evaluation of ischemic states and kits |
| US6461875B1 (en) | 1998-10-02 | 2002-10-08 | Ischemia Technologies, Inc. | Test for rapid evaluation of ischemic states and kit |
| US7449338B2 (en) | 1998-10-02 | 2008-11-11 | Ischemia Technologies, Inc. | Tests for the rapid evaluation of ischemic states and kits |
| US6475743B1 (en) | 1998-10-02 | 2002-11-05 | Ischemia Technologies, Inc. | Marker useful for detection and measurement of free radical damage and method |
| US7070937B1 (en) | 1998-10-02 | 2006-07-04 | Ischemia Technologies, Inc. | Marker useful for detection and measurement of free radical damage and method |
| AU769727B2 (en) * | 1998-10-02 | 2004-02-05 | Ischemia Technologies, Inc. | Tests for the rapid evaluation of ischemic states and kits |
| US6492179B1 (en) | 1998-10-02 | 2002-12-10 | Ischemia Techologies, Inc. | Test for rapid evaluation of ischemic states and kit |
| US7592304B2 (en) | 1999-10-01 | 2009-09-22 | Dmi Life Sciences, Inc. | Metal-binding compounds and uses therefor |
| US7632803B2 (en) | 1999-10-01 | 2009-12-15 | Dmi Life Sciences, Inc. | Metal-binding compounds and uses therefor |
| US6787636B1 (en) | 2000-07-14 | 2004-09-07 | New Century Pharmaceuticals, Inc. | Modified serum albumin with reduced affinity for nickel and copper |
| US7829072B2 (en) | 2000-07-14 | 2010-11-09 | Carter Daniel C | Serum albumin compositions for use in cleansing or dermatological products for skin or hair |
| JP5048201B2 (ja) | 2000-08-04 | 2012-10-17 | ディーエムアイ バイオサイエンシズ インコーポレイテッド | ジケトピペラジン類の使用方法とジケトピペラジン類を含む組成物 |
| AU2002305731A1 (en) * | 2001-05-30 | 2002-12-09 | Ischemia Technology, Inc. | Method and system for optically performing an assay to determine a medical condition |
| US7063782B2 (en) | 2001-11-26 | 2006-06-20 | Ischemia Technologies, Inc. | Electrochemical detection of ischemia |
| DK1571970T3 (da) * | 2002-10-02 | 2011-11-28 | Dmi Biosciences Inc | Diagnose og monitorering af sygdomme |
| NZ539734A (en) * | 2002-10-09 | 2011-07-29 | Dmi Biosciences Inc | Diagnosis and monitoring of inflammation, ischemia and appendicitis |
| CN102210852B (zh) | 2003-05-15 | 2016-10-19 | 安皮奥制药股份有限公司 | T-细胞介导的疾病的治疗 |
| US7074194B2 (en) | 2003-05-19 | 2006-07-11 | Ischemia Technologies, Inc. | Apparatus and method for risk stratification of patients with chest pain of suspected cardiac origin |
| JP5856843B2 (ja) | 2008-05-27 | 2016-02-10 | アンピオ ファーマシューティカルズ，インコーポレイテッド | ジケトピペラジンを用いた医薬組成物 |
| EP2613786A4 (de) | 2010-09-07 | 2013-10-23 | Dmi Acquisition Corp | Behandlung von erkrankungen |
| PH12014500685B1 (en) | 2011-10-10 | 2018-10-03 | Ampio Pharmaceuticals Inc | Treatment of degenerative joint disease |
| JP2014530063A (ja) | 2011-10-10 | 2014-11-17 | アンピオ ファーマシューティカルズ，インコーポレイテッド | 免疫寛容が高められた埋込み型医療用デバイス、ならびに製造方法および埋込み方法 |
| HK1198812A1 (en) | 2011-10-28 | 2015-06-12 | Ampio Pharmaceuticals, Inc. | Treatment of rhinitis |
| CA2906864A1 (en) | 2013-03-15 | 2014-09-18 | Ampio Pharmaceuticals, Inc. | Compositions for the mobilization, homing, expansion and differentiation of stem cells and methods of using the same |
| EP4066836A1 (de) | 2014-08-18 | 2022-10-05 | Ampio Pharmaceuticals, Inc. | Behandlung von gelenkerkrankungen |
| EP3310375A4 (de) | 2015-06-22 | 2019-02-20 | Ampio Pharmaceuticals, Inc. | Verwendung von niedermolekularen fraktionen von humanem serumalbumin bei der behandlung von erkrankungen |
| TWI568746B (zh) | 2016-07-06 | 2017-02-01 | 高雄醫學大學 | 用以評估自由基產生能力的寡肽及方法 |
-
1999
- 1999-10-01 DE DE69939121T patent/DE69939121D1/de not_active Revoked
- 1999-10-01 AU AU62793/99A patent/AU6279399A/en not_active Abandoned
- 1999-10-01 AT AT99950055T patent/ATE401342T1/de not_active IP Right Cessation
- 1999-10-01 EP EP99950055A patent/EP1117686B1/de not_active Revoked
- 1999-10-01 WO PCT/US1999/022746 patent/WO2000020454A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| EP1117686A1 (de) | 2001-07-25 |
| WO2000020454A1 (en) | 2000-04-13 |
| AU6279399A (en) | 2000-04-26 |
| EP1117686B1 (de) | 2008-07-16 |
| DE69939121D1 (de) | 2008-08-28 |
| EP1117686A4 (de) | 2005-01-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |