ATE401342T1 - Verfahren und materialien zum nachweis und zur messung von durch freie radikale verursachten schäden - Google Patents
Verfahren und materialien zum nachweis und zur messung von durch freie radikale verursachten schädenInfo
- Publication number
- ATE401342T1 ATE401342T1 AT99950055T AT99950055T ATE401342T1 AT E401342 T1 ATE401342 T1 AT E401342T1 AT 99950055 T AT99950055 T AT 99950055T AT 99950055 T AT99950055 T AT 99950055T AT E401342 T1 ATE401342 T1 AT E401342T1
- Authority
- AT
- Austria
- Prior art keywords
- albumin
- marker
- measurement
- detection
- detecting
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 4
- 102000009027 Albumins Human genes 0.000 abstract 6
- 108010088751 Albumins Proteins 0.000 abstract 6
- 239000003550 marker Substances 0.000 abstract 5
- 150000003254 radicals Chemical class 0.000 abstract 5
- 238000005259 measurement Methods 0.000 abstract 4
- 230000004075 alteration Effects 0.000 abstract 3
- 238000001514 detection method Methods 0.000 abstract 3
- 229910017052 cobalt Inorganic materials 0.000 abstract 2
- 239000010941 cobalt Substances 0.000 abstract 2
- GUTLYIVDDKVIGB-UHFFFAOYSA-N cobalt atom Chemical compound [Co] GUTLYIVDDKVIGB-UHFFFAOYSA-N 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 201000010099 disease Diseases 0.000 abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 abstract 1
- 102000007562 Serum Albumin Human genes 0.000 abstract 1
- 108010071390 Serum Albumin Proteins 0.000 abstract 1
- 238000004458 analytical method Methods 0.000 abstract 1
- 108010036999 aspartyl-alanyl-histidyl-lysine Proteins 0.000 abstract 1
- 239000008280 blood Substances 0.000 abstract 1
- 210000004369 blood Anatomy 0.000 abstract 1
- 125000003636 chemical group Chemical group 0.000 abstract 1
- 229940121657 clinical drug Drugs 0.000 abstract 1
- 229910052802 copper Inorganic materials 0.000 abstract 1
- 239000010949 copper Substances 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 238000003018 immunoassay Methods 0.000 abstract 1
- 238000010324 immunological assay Methods 0.000 abstract 1
- 239000002184 metal Substances 0.000 abstract 1
- 229910052751 metal Inorganic materials 0.000 abstract 1
- 229910021645 metal ion Inorganic materials 0.000 abstract 1
- 150000002739 metals Chemical class 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 238000011896 sensitive detection Methods 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/76—Albumins
- C07K14/765—Serum albumin, e.g. HSA
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6848—Methods of protein analysis involving mass spectrometry
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Food Science & Technology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Biophysics (AREA)
- Bioinformatics & Computational Biology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Genetics & Genomics (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Sampling And Sample Adjustment (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Peptides Or Proteins (AREA)
- Investigating And Analyzing Materials By Characteristic Methods (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10296298P | 1998-10-02 | 1998-10-02 | |
| US09/165,961 US6475743B1 (en) | 1998-10-02 | 1998-10-02 | Marker useful for detection and measurement of free radical damage and method |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE401342T1 true ATE401342T1 (de) | 2008-08-15 |
Family
ID=26799929
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99950055T ATE401342T1 (de) | 1998-10-02 | 1999-10-01 | Verfahren und materialien zum nachweis und zur messung von durch freie radikale verursachten schäden |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP1117686B1 (de) |
| AT (1) | ATE401342T1 (de) |
| AU (1) | AU6279399A (de) |
| DE (1) | DE69939121D1 (de) |
| WO (1) | WO2000020454A1 (de) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7282369B2 (en) | 1998-10-02 | 2007-10-16 | Ischemia Technologies, Inc. | Tests for the rapid evaluation of ischemic states and kits |
| US6492179B1 (en) | 1998-10-02 | 2002-12-10 | Ischemia Techologies, Inc. | Test for rapid evaluation of ischemic states and kit |
| US6461875B1 (en) | 1998-10-02 | 2002-10-08 | Ischemia Technologies, Inc. | Test for rapid evaluation of ischemic states and kit |
| US7070937B1 (en) | 1998-10-02 | 2006-07-04 | Ischemia Technologies, Inc. | Marker useful for detection and measurement of free radical damage and method |
| EP1125107A4 (de) * | 1998-10-02 | 2002-04-17 | Ischemia Tech Inc | Test zur schnellen bestimmung von ischämischen zuständen und testsatz dafür |
| US6475743B1 (en) | 1998-10-02 | 2002-11-05 | Ischemia Technologies, Inc. | Marker useful for detection and measurement of free radical damage and method |
| US7449338B2 (en) | 1998-10-02 | 2008-11-11 | Ischemia Technologies, Inc. | Tests for the rapid evaluation of ischemic states and kits |
| US7632803B2 (en) | 1999-10-01 | 2009-12-15 | Dmi Life Sciences, Inc. | Metal-binding compounds and uses therefor |
| US7592304B2 (en) | 1999-10-01 | 2009-09-22 | Dmi Life Sciences, Inc. | Metal-binding compounds and uses therefor |
| US7829072B2 (en) | 2000-07-14 | 2010-11-09 | Carter Daniel C | Serum albumin compositions for use in cleansing or dermatological products for skin or hair |
| US6787636B1 (en) | 2000-07-14 | 2004-09-07 | New Century Pharmaceuticals, Inc. | Modified serum albumin with reduced affinity for nickel and copper |
| AU2001279313B2 (en) | 2000-08-04 | 2007-03-01 | Ampio Pharmaceuticals, Inc. | Method of using diketopiperazines and composition containing them |
| US20050021235A1 (en) * | 2001-05-30 | 2005-01-27 | Raphael Bar-Or | Method and system for optically performing an assay to determine a medical condition |
| AU2002352959B2 (en) | 2001-11-26 | 2008-04-10 | Ischemia Technologies, Inc. | Electrochemical detection of ischemia |
| ATE520981T1 (de) | 2002-10-02 | 2011-09-15 | Dmi Biosciences Inc | Diagnose und überwachung von krankheiten |
| US20040175754A1 (en) * | 2002-10-09 | 2004-09-09 | David Bar-Or | Diagnosis and monitoring of inflammation, ischemia and appendicitis |
| CA3050734A1 (en) | 2003-05-15 | 2004-12-02 | Ampio Pharmaceuticals, Inc. | Treatment of t-cell mediated diseases |
| US7074194B2 (en) | 2003-05-19 | 2006-07-11 | Ischemia Technologies, Inc. | Apparatus and method for risk stratification of patients with chest pain of suspected cardiac origin |
| WO2009146320A1 (en) | 2008-05-27 | 2009-12-03 | Dmi Life Sciences, Inc. | Therapeutic methods and compounds |
| US8507496B2 (en) | 2010-09-07 | 2013-08-13 | Dmi Acquisition Corp. | Treatment of diseases |
| EP2766029B1 (de) | 2011-10-10 | 2020-03-25 | Ampio Pharmaceuticals, Inc. | Behandlung degenerativer gelenkerkrankungen |
| EA027343B1 (ru) | 2011-10-10 | 2017-07-31 | Ампио Фармасьютикалз, Инк. | Имплантируемые устройства медицинского назначения с повышенной иммунной толерантностью и способы изготовления и имплантирования |
| CA2846394A1 (en) | 2011-10-28 | 2013-05-02 | Ampio Pharmaceuticals, Inc. | Treatment of rhinitis |
| BR112015020469A2 (pt) | 2013-03-15 | 2020-01-28 | Ampio Pharmaceuticals Inc | Usos de da-dkp, composição e método para fornecimento de células-tronco a umindivíduo |
| AU2015305611B2 (en) | 2014-08-18 | 2020-04-23 | Ampio Pharmaceuticals, Inc. | Treatment of joint conditions |
| US11389512B2 (en) | 2015-06-22 | 2022-07-19 | Ampio Pharmaceuticals, Inc. | Use of low molecular weight fractions of human serum albumin in treating diseases |
-
1999
- 1999-10-01 EP EP99950055A patent/EP1117686B1/de not_active Revoked
- 1999-10-01 DE DE69939121T patent/DE69939121D1/de not_active Revoked
- 1999-10-01 AT AT99950055T patent/ATE401342T1/de not_active IP Right Cessation
- 1999-10-01 WO PCT/US1999/022746 patent/WO2000020454A1/en not_active Ceased
- 1999-10-01 AU AU62793/99A patent/AU6279399A/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP1117686A4 (de) | 2005-01-12 |
| EP1117686A1 (de) | 2001-07-25 |
| DE69939121D1 (de) | 2008-08-28 |
| AU6279399A (en) | 2000-04-26 |
| WO2000020454A1 (en) | 2000-04-13 |
| EP1117686B1 (de) | 2008-07-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |