BR0111975A - Fator, composição, veìculo, ligando, kits de diagnósticos, processos para detectar uma prpsc em uma amostra, e para remover prpsc de material biológico, método para diagnosticar encefalopatias espongiformes humanas transmissìveis e encefalopatias de prìons de animais, e, uso de um fator - Google Patents

Fator, composição, veìculo, ligando, kits de diagnósticos, processos para detectar uma prpsc em uma amostra, e para remover prpsc de material biológico, método para diagnosticar encefalopatias espongiformes humanas transmissìveis e encefalopatias de prìons de animais, e, uso de um fator

Info

Publication number
BR0111975A
BR0111975A BR0111975-3A BR0111975A BR0111975A BR 0111975 A BR0111975 A BR 0111975A BR 0111975 A BR0111975 A BR 0111975A BR 0111975 A BR0111975 A BR 0111975A
Authority
BR
Brazil
Prior art keywords
prpsc
factor
encephalopathies
sample
processes
Prior art date
Application number
BR0111975-3A
Other languages
English (en)
Original Assignee
Universitot Zuerich
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/IB2000/000849 external-priority patent/WO2001023425A1/en
Application filed by Universitot Zuerich filed Critical Universitot Zuerich
Publication of BR0111975A publication Critical patent/BR0111975A/pt

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482—Serine endopeptidases (3.4.21)
    • A61K38/484—Plasmin (3.4.21.7)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/968—Plasmin, i.e. fibrinolysin
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/28—Neurological disorders
    • G01N2800/2814—Dementia; Cognitive disorders
    • G01N2800/2828—Prion diseases

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Food Science & Technology (AREA)
  • Veterinary Medicine (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

"FATOR, COMPOSIçãO, VEìCULO, LIGANDO, KITS DE DIAGNóSTICOS, PROCESSOS PARA DETECTAR UMA PRPSC EM UMA AMOSTRA, E PARA REMOVER PRPSC DE MATERIAL BIOLóGICO, MéTODO PARA DIAGNOSTICAR ENCEFALOPATIAS ESPONGIFORMES HUMANAS TRANSMISSìVEIS E ENCEFALOPATIAS DE PRìONS DE ANIMAIS, E, USO DE UM FATOR". São apresentados métodos e ferramentas para a concentração e detecção, bem como quantificação, de proteínas patológicas de príons, bem como agentes a serem usados na dita detecção e/ou na prevenção ou tratamento de doenças de príons. Ditos agentes são fatores com atividades de ligação de príons observadas no soro sang³íneo e no plasma sang³íneo.
BR0111975-3A 2000-06-26 2001-03-27 Fator, composição, veìculo, ligando, kits de diagnósticos, processos para detectar uma prpsc em uma amostra, e para remover prpsc de material biológico, método para diagnosticar encefalopatias espongiformes humanas transmissìveis e encefalopatias de prìons de animais, e, uso de um fator BR0111975A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/IB2000/000849 WO2001023425A1 (en) 1999-09-28 2000-06-26 Factors having prion-binding activity in serum and plasma and agents to detect transmissible spongiform encephalopathitis
PCT/EP2001/003481 WO2002000713A1 (en) 2000-06-26 2001-03-27 Prion-binding activity in serum and plasma determined as plasminogen and fibrinogen

Publications (1)

Publication Number Publication Date
BR0111975A true BR0111975A (pt) 2003-07-01

Family

ID=11003939

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0111975-3A BR0111975A (pt) 2000-06-26 2001-03-27 Fator, composição, veìculo, ligando, kits de diagnósticos, processos para detectar uma prpsc em uma amostra, e para remover prpsc de material biológico, método para diagnosticar encefalopatias espongiformes humanas transmissìveis e encefalopatias de prìons de animais, e, uso de um fator

Country Status (6)

Country Link
EP (1) EP1294759A1 (pt)
JP (1) JP2004501626A (pt)
AU (1) AU2001250406A1 (pt)
BR (1) BR0111975A (pt)
CA (1) CA2413742A1 (pt)
WO (1) WO2002000713A1 (pt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100526884C (zh) * 2002-02-28 2009-08-12 米克罗森拜奥菲哲有限公司 病理形式朊病毒蛋白的结合
DE10230141B4 (de) * 2002-07-04 2004-07-15 Priontype Gmbh Verfahren und Kit zur Anreicherung und zum Nachweis von veränderten Prion-Proteinen (PrPSc)
US7482172B2 (en) 2005-09-19 2009-01-27 Ortho-Clinical Diagnostics, Inc. Peptides for discrimination of prions
AU2005209592B2 (en) 2004-09-30 2012-07-12 Ortho-Clinical Diagnostics, Inc. Peptides for discrimination of prions
AU2006322247A1 (en) * 2005-12-08 2007-06-14 South Dakota State University Methods of in vitro propagation and detection of infectious prion
FR2940446A1 (fr) * 2008-12-22 2010-06-25 Lfb Biotechnologies Procede de detection d'une infection par prion
FR2973114A1 (fr) * 2011-03-21 2012-09-28 Ets Francais Du Sang Nanobilles recouvertes de plasminogene comme support direct d'amplification cyclique de la proteine prion prpsc
EP3064757B1 (en) 2015-03-05 2018-11-14 Continental Automotive GmbH Method for manufacturing an injector for injecting fluid and injector for injecting fluid

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19925073C2 (de) * 1999-06-01 2001-07-19 Stefan Weiss Nucleinsäuremoleküle mit spezifischer Erkennung von nativem PrP·S··c·, Herstellung und Verwendung
AU783484B2 (en) * 1999-06-23 2005-11-03 Thallion Pharmaceuticals Inc. Prion protein peptides and uses thereof
CA2385743A1 (en) * 1999-09-28 2001-04-05 Universitat Zurich Factors having prion-binding activity in serum and plasma and agents to detect transmissible spongiform encephalopathitis

Also Published As

Publication number Publication date
AU2001250406A1 (en) 2002-01-08
CA2413742A1 (en) 2002-01-03
EP1294759A1 (en) 2003-03-26
WO2002000713A1 (en) 2002-01-03
JP2004501626A (ja) 2004-01-22

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Legal Events

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B08K Lapse as no evidence of payment of the annual fee has been furnished to inpi (acc. art. 87)

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