AR058510A1 - Procedimiento de diagnostico de enfermedades hepaticas y de muestreo de moleculas para el tratamiento de estas enfermedades - Google Patents

Procedimiento de diagnostico de enfermedades hepaticas y de muestreo de moleculas para el tratamiento de estas enfermedades

Info

Publication number
AR058510A1
AR058510A1 ARP060104906A ARP060104906A AR058510A1 AR 058510 A1 AR058510 A1 AR 058510A1 AR P060104906 A ARP060104906 A AR P060104906A AR P060104906 A ARP060104906 A AR P060104906A AR 058510 A1 AR058510 A1 AR 058510A1
Authority
AR
Argentina
Prior art keywords
diseases
diagnosis
treatment
sampling
molecules
Prior art date
Application number
ARP060104906A
Other languages
English (en)
Inventor
Dominique Simon
Sylvaine Galiegue
Isabelle Buisson
Pierre Casellas
Jean Marchand
Hubert Vidal
Original Assignee
Sanofi Aventis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis filed Critical Sanofi Aventis
Publication of AR058510A1 publication Critical patent/AR058510A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/92—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving lipids, e.g. cholesterol, lipoproteins, or their receptors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/136—Screening for pharmacological compounds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/775—Apolipopeptides

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Analytical Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Biophysics (AREA)
  • Cell Biology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

Un método de diagnostico de enfermedades hepáticas que comprende la medida de la expresion de la apolipoproteína A4 en las células o tejidos hepáticos y en la circulacion (sangre, plasma, suero) por método PCR, mediante un anticuerpo específico de esta proteina entre otros. Además se refiere a un procedimiento de muestreo de moléculas para el tratamiento de estas enfermedades mediante la puesta en contacto de dichos compuestos con un mamífero y la medida de la expresion de la apolipoproteína A4 en dichas células de origen hepático o en la circulacion de dicho mamífero.
ARP060104906A 2005-11-10 2006-11-09 Procedimiento de diagnostico de enfermedades hepaticas y de muestreo de moleculas para el tratamiento de estas enfermedades AR058510A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0511432A FR2893136A1 (fr) 2005-11-10 2005-11-10 Procedes de diagnostic de maladies hepatiques et de criblage de molecules pour le traitement de ces maladies

Publications (1)

Publication Number Publication Date
AR058510A1 true AR058510A1 (es) 2008-02-06

Family

ID=36972931

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP060104906A AR058510A1 (es) 2005-11-10 2006-11-09 Procedimiento de diagnostico de enfermedades hepaticas y de muestreo de moleculas para el tratamiento de estas enfermedades

Country Status (13)

Country Link
US (1) US20090220958A1 (es)
EP (1) EP1949110A2 (es)
JP (1) JP2009515514A (es)
KR (1) KR20080074121A (es)
CN (1) CN101310187A (es)
AR (1) AR058510A1 (es)
AU (1) AU2006314369A1 (es)
BR (1) BRPI0618490A2 (es)
CA (1) CA2627082A1 (es)
FR (1) FR2893136A1 (es)
RU (1) RU2008123385A (es)
TW (1) TW200804811A (es)
WO (1) WO2007057548A2 (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2009226246A1 (en) * 2008-03-21 2009-09-24 Podiceps B.V. Diagnostic of pre-symptomatic metabolic syndrome
WO2010073870A1 (ja) * 2008-12-24 2010-07-01 学校法人 慶應義塾 肝臓疾患マーカー、その測定方法、装置及び医薬品の検定方法
ES2821383T3 (es) * 2012-10-17 2021-04-26 Enterome Firmas genéticas de trastornos inflamatorios relacionados con el hígado y la enfermedad de Crohn
WO2019167874A1 (ja) 2018-02-27 2019-09-06 エーザイ・アール・アンド・ディー・マネジメント株式会社 Ａｐｏａ４に対するモノクローナル抗体、免疫学的測定方法及び測定用キット
CN113018459A (zh) * 2021-03-09 2021-06-25 百码科技(深圳)有限公司 一种基因治疗减肥的生物药剂及其制备方法
CN112891561A (zh) * 2021-03-09 2021-06-04 百码科技(深圳)有限公司 一种基因治疗脂肪肝的生物药剂及其制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2686605B1 (fr) * 1992-01-27 1994-03-11 Rhone Poulenc Rorer Sa Nouveaux polypeptides, leur preparation et leur utilisation.
US5925333A (en) * 1995-11-15 1999-07-20 Massachusetts Institute Of Technology Methods for modulation of lipid uptake
AU2001251245A1 (en) * 2000-04-05 2001-10-23 Genaissance Pharmaceuticals, Inc. Haplotypes of the apoa4 gene
US6727066B2 (en) * 2000-07-28 2004-04-27 Incyte Corporation Genes expressed in treated human C3A liver cell cultures
US20060009410A1 (en) * 2002-11-13 2006-01-12 Crooke Rosanne M Effects of apolipoprotein B inhibition on gene expression profiles in animals
AU2003296085A1 (en) * 2002-12-24 2004-07-22 Nitto Boseki Co., Ltd. Marker proteins for diagnosing liver disease and method of diagnosing liver disease using the same

Also Published As

Publication number Publication date
EP1949110A2 (fr) 2008-07-30
FR2893136A1 (fr) 2007-05-11
WO2007057548A3 (fr) 2007-07-26
CA2627082A1 (fr) 2007-05-24
BRPI0618490A2 (pt) 2011-08-30
AU2006314369A1 (en) 2007-05-24
RU2008123385A (ru) 2009-12-20
TW200804811A (en) 2008-01-16
KR20080074121A (ko) 2008-08-12
CN101310187A (zh) 2008-11-19
US20090220958A1 (en) 2009-09-03
JP2009515514A (ja) 2009-04-16
WO2007057548A2 (fr) 2007-05-24

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