BR0317394A - Uso de nicotinamida n-metiltransferase como um marcador para câncer colorretal - Google Patents

Uso de nicotinamida n-metiltransferase como um marcador para câncer colorretal

Info

Publication number
BR0317394A
BR0317394A BR0317394-1A BR0317394A BR0317394A BR 0317394 A BR0317394 A BR 0317394A BR 0317394 A BR0317394 A BR 0317394A BR 0317394 A BR0317394 A BR 0317394A
Authority
BR
Brazil
Prior art keywords
colorectal cancer
methyltransferase
nicotinamide
marker
diagnosis
Prior art date
Application number
BR0317394-1A
Other languages
English (en)
Inventor
Peter Berndt
Marie-Luise Hagmann
Johann Karl
Theresa Kott
Hanno Langen
Stefan Palme
Markus Roessler
Wolfgang Rollinger
Michael Tacke
Werner Zolg
Original Assignee
Roffmann La Roche Ag F
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roffmann La Roche Ag F filed Critical Roffmann La Roche Ag F
Publication of BR0317394A publication Critical patent/BR0317394A/pt

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57419—Specifically defined cancers of colon
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/48—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase

Abstract

"USO DE NICOTINAMIDA N-METILTRANSFERASE COMO UM MARCADOR PARA CâNCER COLORRETAL". A presente invenção refere-se ao diagnóstico precoce de câncer colorretal. Descreve o uso da proteína nicotinamida N-metiltransferase (NNMT) no diagnóstico de câncer colorretal. Refere-se a um método para o diagnóstico de câncer colorretal a partir de uma amostra líquida, derivada de um indivíduo medindo a NNMT nesta amostra. A medição de NNMT, por exemplo, pode ser usada na detecção precoce ou no diagnóstico de câncer colorretal.
BR0317394-1A 2002-12-20 2003-12-19 Uso de nicotinamida n-metiltransferase como um marcador para câncer colorretal BR0317394A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP02028715 2002-12-20
PCT/EP2003/014583 WO2004057336A2 (en) 2002-12-20 2003-12-19 Use of nicotinamide n-methyltransferase as a marker for colorectal cancer

Publications (1)

Publication Number Publication Date
BR0317394A true BR0317394A (pt) 2005-11-16

Family

ID=32668733

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0317394-1A BR0317394A (pt) 2002-12-20 2003-12-19 Uso de nicotinamida n-metiltransferase como um marcador para câncer colorretal

Country Status (14)

Country Link
US (1) US7205118B2 (pt)
EP (1) EP1579220B1 (pt)
JP (1) JP4248496B2 (pt)
KR (1) KR100711046B1 (pt)
CN (1) CN100437115C (pt)
AT (1) ATE370414T1 (pt)
AU (1) AU2003296684A1 (pt)
BR (1) BR0317394A (pt)
CA (1) CA2510377C (pt)
DE (1) DE60315715T2 (pt)
ES (1) ES2291750T3 (pt)
HK (1) HK1088947A1 (pt)
MX (1) MXPA05006382A (pt)
WO (1) WO2004057336A2 (pt)

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CA2510377C (en) 2002-12-20 2009-11-17 F. Hoffmann-La Roche Ag Use of nicotinamide n-methyltransferase as a marker for colorectal cancer
EP1761780A1 (en) * 2004-06-18 2007-03-14 Roche Diagnostics GmbH Use of inorganic pyrophosphatase as a marker for colorectal cancer
ES2323429T3 (es) 2004-12-23 2009-07-15 F. Hoffmann-La Roche Ag Uso de la asc, como marcador para cancer colorrectal.
WO2006066916A1 (en) * 2004-12-23 2006-06-29 Roche Diagnostics Gmbh Use of microsomal dipeptidase as a marker for colorectal cancer
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DE602005026587D1 (de) 2005-08-19 2011-04-07 Indivumed Gmbh Verwendung eines endoplasmin-fragments und von derivaten davon als biomarker für kolorektaladenom und/oder -karzinom; nachweisverfahren und testsystem
EP1966609A1 (en) * 2005-12-22 2008-09-10 Roche Diagnostics GmbH Use of a marker combination comprising osteopontin and carcinoembryonic antigen in the assessment of colorectal cancer
DE602007006671D1 (de) * 2006-08-01 2010-07-01 Roche Diagnostics Gmbh Verwendung von nnmt als marker für lungenkrebs
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KR101458483B1 (ko) * 2007-08-06 2014-11-10 제노마인(주) 신장암 진단 조성물 및 키트
CN102317784B (zh) 2008-12-22 2014-07-16 霍夫曼-拉罗奇有限公司 作为癌症标记物的armet
US10815517B2 (en) 2009-04-28 2020-10-27 Roche Diagnostics Operations, Inc. Use of DPPIV/seprase as a marker for cancer
WO2010136163A1 (en) 2009-05-29 2010-12-02 Roche Diagnostics Gmbh Secernin-1 as a marker for cancer
ES2493070T3 (es) 2009-07-16 2014-09-11 F. Hoffmann-La Roche Ag Flap endonucleasa-1 como marcador para el cáncer
CN102375049A (zh) * 2010-08-04 2012-03-14 索尼公司 生物信息获取方法和烟酰胺代谢物测量方法
ES2583084T3 (es) * 2011-03-11 2016-09-19 F. Hoffmann-La Roche Ag NNMT como marcador para la enfermedad pulmonar obstructiva crónica (EPOC)
CN106461669A (zh) 2014-05-13 2017-02-22 瓦斯特空公司 外周血及其单核细胞中的甲硫氨酸氨肽酶过表达作为结肠直肠癌筛查、诊断和预后的标记物
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CN110308281B (zh) * 2019-06-06 2022-08-23 北京蛋白质组研究中心 一种泛素链固相检测方法和应用

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Also Published As

Publication number Publication date
DE60315715D1 (de) 2007-09-27
CN100437115C (zh) 2008-11-26
US20060003368A1 (en) 2006-01-05
CN1742204A (zh) 2006-03-01
EP1579220B1 (en) 2007-08-15
US7205118B2 (en) 2007-04-17
CA2510377A1 (en) 2004-07-08
JP2006510889A (ja) 2006-03-30
WO2004057336A2 (en) 2004-07-08
CA2510377C (en) 2009-11-17
KR20050114604A (ko) 2005-12-06
JP4248496B2 (ja) 2009-04-02
HK1088947A1 (en) 2006-11-17
ATE370414T1 (de) 2007-09-15
WO2004057336A3 (en) 2005-01-20
AU2003296684A1 (en) 2004-07-14
MXPA05006382A (es) 2005-10-24
ES2291750T3 (es) 2008-03-01
DE60315715T2 (de) 2008-06-05
EP1579220A2 (en) 2005-09-28
KR100711046B1 (ko) 2007-04-24

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 6A, 7A E 8A ANUIDADE(S).

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2144 DE 07/02/2012.