ATE554389T1 - Apex als marker für lungenkrebs - Google Patents

Apex als marker für lungenkrebs

Info

Publication number
ATE554389T1
ATE554389T1 AT08716640T AT08716640T ATE554389T1 AT E554389 T1 ATE554389 T1 AT E554389T1 AT 08716640 T AT08716640 T AT 08716640T AT 08716640 T AT08716640 T AT 08716640T AT E554389 T1 ATE554389 T1 AT E554389T1
Authority
AT
Austria
Prior art keywords
lung cancer
apex
marker
assessment
relates
Prior art date
Application number
AT08716640T
Other languages
English (en)
Inventor
Marie-Luise Hagmann
Johann Karl
Julia Kloeckner
Markus Roessler
Michael Tacke
Michael Thierolf
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of ATE554389T1 publication Critical patent/ATE554389T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/5752—Immunoassay; Biospecific binding assay; Materials therefor for cancer of the lungs
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/5758—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites
    • G01N33/57585—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites involving compounds identifiable in body fluids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/988—Lyases (4.), e.g. aldolases, heparinase, enolases, fumarase

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AT08716640T 2007-03-23 2008-03-19 Apex als marker für lungenkrebs ATE554389T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP07006079 2007-03-23
PCT/EP2008/002224 WO2008116592A1 (en) 2007-03-23 2008-03-19 Apex as a marker for lung cancer

Publications (1)

Publication Number Publication Date
ATE554389T1 true ATE554389T1 (de) 2012-05-15

Family

ID=38480598

Family Applications (1)

Application Number Title Priority Date Filing Date
AT08716640T ATE554389T1 (de) 2007-03-23 2008-03-19 Apex als marker für lungenkrebs

Country Status (8)

Country Link
US (1) US20110097756A1 (de)
EP (1) EP2130048B1 (de)
JP (1) JP5079023B2 (de)
CN (1) CN101641599A (de)
AT (1) ATE554389T1 (de)
CA (1) CA2681577A1 (de)
ES (1) ES2384125T3 (de)
WO (1) WO2008116592A1 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5690039B2 (ja) 2004-06-04 2015-03-25 バイオセラノスティクス インコーポレイテッドＢｉｏｔｈｅｒａｎｏｓｔｉｃｓ，Ｉｎｃ． 腫瘍の同定
US20120258442A1 (en) * 2011-04-09 2012-10-11 bio Theranostics, Inc. Determining tumor origin
WO2006132971A2 (en) 2005-06-03 2006-12-14 Aviaradx, Inc. Identification of tumors and tissues
JP5172020B2 (ja) * 2008-11-12 2013-03-27 エフ．ホフマン−ラ ロシュ アーゲー 癌のマーカーとしてのｐａｃａｐ
CN102439455B (zh) 2009-05-15 2015-01-07 霍夫曼-拉罗奇有限公司 作为肺癌标志物的cybp
CA2760366A1 (en) 2009-05-29 2010-12-02 F.Hoffmann-La Roche Ag Secernin-1 as a marker for cancer
CN101930004A (zh) * 2009-06-24 2010-12-29 中国科学院上海生命科学研究院 Apex1用作检测肝细胞癌的蛋白质分子标记的应用
KR101251222B1 (ko) * 2010-12-08 2013-04-08 충남대학교산학협력단 ＡＰＥ1/Ｒｅｆ-1을 함유하는 방광암 진단용 조성물, 및 이를 이용한 방광암 진단 키트
ES2578502T3 (es) * 2011-03-11 2016-07-27 Roche Diagniostics Gmbh APEX como marcador de la enfermedad pulmonar obstructiva crónica (EPOC)
CN102435748B (zh) * 2011-11-25 2014-07-16 广东药学院 一种双抗夹心酶联免疫检测试剂盒及其制备方法
CN102507951B (zh) * 2011-11-25 2014-11-19 广东药学院 一种联合检测肿瘤标志物的酶联免疫检测试剂盒
WO2014190230A1 (en) * 2013-05-23 2014-11-27 Iphenotype Llc Phenotypic integrated social search database and method
CN105891482B (zh) * 2016-03-29 2017-12-19 复旦大学附属中山医院 一种基于生物标志物谱针对中国农村人口肺结节人群的肺癌风险预测模型
CN106018807A (zh) * 2016-05-11 2016-10-12 卢氏实验室公司 一种快速诊断和监控肺癌的免疫层析检测条及其制备方法
CN106053816B (zh) * 2016-08-19 2018-01-05 四川大学华西第二医院 肺癌诊断试剂盒
CN106645722B (zh) * 2016-10-17 2018-09-04 四川大学华西第二医院 一种肺癌筛查试剂盒
CN107860852A (zh) * 2017-11-23 2018-03-30 南宁科城汇信息科技有限公司 一种基于iTRAQ联合LC、MALDI的差异蛋白组学

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0923738A1 (de) * 1996-06-11 1999-06-23 Advanced Research & Technology Institute Verfahren und zubereitungen für die verwendung von apurinischen/apyrimidinischen endonukleasen
CN1398189A (zh) * 1998-12-23 2003-02-19 G.D.西尔公司 用于治疗肿瘤形成的放疗与cox－2抑制剂的联合治疗
US20030003454A1 (en) * 2001-03-23 2003-01-02 Yeda Research And Development Co. Ltd. At The Weizmann Institute Of Science Methods and kits for determining a risk to develop cancer, for evaluating an effectiveness and dosage of cancer therapy and for correlating between an activity of a DNA repair enzyme and a cancer
IL158003A0 (en) * 2001-03-23 2004-03-28 Yeda Res & Dev Methods and kits for determining a risk to develop cancer, for evaluating an effectiveness and dosage of cancer therapy and for correlating between an activity of a dna repair enzyme and a cancer
JP3691798B2 (ja) * 2002-02-18 2005-09-07 三洋化成工業株式会社 血液中の腫瘍マーカー定量方法
US20050181375A1 (en) * 2003-01-10 2005-08-18 Natasha Aziz Novel methods of diagnosis of metastatic cancer, compositions and methods of screening for modulators of metastatic cancer
WO2005050164A2 (en) * 2003-11-13 2005-06-02 Georgia Tech Research Corporation Detection systems and methods
US7611845B2 (en) * 2004-12-17 2009-11-03 Siemens Healthcare Diagnostics Inc. Serum levels of HER2/neu as an indicator of clinical state and prognosis of prostate cancer
CN101273144B (zh) * 2005-07-27 2011-12-28 肿瘤疗法科学股份有限公司 诊断食道癌的方法
US20100086920A1 (en) * 2006-09-18 2010-04-08 Cmed Technologies Ltd. Method to assess cancer susceptibility and differential diagnosis of metastases of unknown primary tumors
KR20100015438A (ko) * 2007-03-09 2010-02-12 트리패스 이미징, 인코포레이티드 Ｈｅ4 모노클로날 항체 및 이의 사용 방법

Also Published As

Publication number Publication date
EP2130048B1 (de) 2012-04-18
WO2008116592A1 (en) 2008-10-02
ES2384125T3 (es) 2012-06-29
JP2010521688A (ja) 2010-06-24
CN101641599A (zh) 2010-02-03
JP5079023B2 (ja) 2012-11-21
CA2681577A1 (en) 2008-10-02
US20110097756A1 (en) 2011-04-28
EP2130048A1 (de) 2009-12-09

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