|
US2429001A
(en)
|
1946-12-28 |
1947-10-14 |
Axel H Stone |
Artificial hand
|
|
FR2413974A1
(fr)
|
1978-01-06 |
1979-08-03 |
David Bernard |
Sechoir pour feuilles imprimees par serigraphie
|
|
US4307016A
(en)
|
1978-03-24 |
1981-12-22 |
Takeda Chemical Industries, Ltd. |
Demethyl maytansinoids
|
|
US4256746A
(en)
|
1978-11-14 |
1981-03-17 |
Takeda Chemical Industries |
Dechloromaytansinoids, their pharmaceutical compositions and method of use
|
|
JPS55102583A
(en)
|
1979-01-31 |
1980-08-05 |
Takeda Chem Ind Ltd |
20-acyloxy-20-demethylmaytansinoid compound
|
|
JPS55162791A
(en)
|
1979-06-05 |
1980-12-18 |
Takeda Chem Ind Ltd |
Antibiotic c-15003pnd and its preparation
|
|
JPS5645483A
(en)
|
1979-09-19 |
1981-04-25 |
Takeda Chem Ind Ltd |
C-15003phm and its preparation
|
|
EP0028683A1
(en)
|
1979-09-21 |
1981-05-20 |
Takeda Chemical Industries, Ltd. |
Antibiotic C-15003 PHO and production thereof
|
|
JPS5645485A
(en)
|
1979-09-21 |
1981-04-25 |
Takeda Chem Ind Ltd |
Production of c-15003pnd
|
|
WO1982001188A1
(en)
|
1980-10-08 |
1982-04-15 |
Takeda Chemical Industries Ltd |
4,5-deoxymaytansinoide compounds and process for preparing same
|
|
US4450254A
(en)
|
1980-11-03 |
1984-05-22 |
Standard Oil Company |
Impact improvement of high nitrile resins
|
|
US4315929A
(en)
|
1981-01-27 |
1982-02-16 |
The United States Of America As Represented By The Secretary Of Agriculture |
Method of controlling the European corn borer with trewiasine
|
|
US4313946A
(en)
|
1981-01-27 |
1982-02-02 |
The United States Of America As Represented By The Secretary Of Agriculture |
Chemotherapeutically active maytansinoids from Trewia nudiflora
|
|
US4563304A
(en)
|
1981-02-27 |
1986-01-07 |
Pharmacia Fine Chemicals Ab |
Pyridine compounds modifying proteins, polypeptides or polysaccharides
|
|
JPS57192389A
(en)
|
1981-05-20 |
1982-11-26 |
Takeda Chem Ind Ltd |
Novel maytansinoid
|
|
US4474893A
(en)
|
1981-07-01 |
1984-10-02 |
The University of Texas System Cancer Center |
Recombinant monoclonal antibodies
|
|
US4714681A
(en)
|
1981-07-01 |
1987-12-22 |
The Board Of Reagents, The University Of Texas System Cancer Center |
Quadroma cells and trioma cells and methods for the production of same
|
|
US4427588A
(en)
|
1982-11-08 |
1984-01-24 |
Bristol-Myers Company |
Process for conversion of oxotomaymycin to tomaymycin
|
|
US4816567A
(en)
|
1983-04-08 |
1989-03-28 |
Genentech, Inc. |
Recombinant immunoglobin preparations
|
|
US4699880A
(en)
|
1984-09-25 |
1987-10-13 |
Immunomedics, Inc. |
Method of producing monoclonal anti-idiotype antibody
|
|
JPS61109717A
(ja)
|
1984-11-02 |
1986-05-28 |
Teruhiko Beppu |
抗腫瘍剤
|
|
US6492107B1
(en)
|
1986-11-20 |
2002-12-10 |
Stuart Kauffman |
Process for obtaining DNA, RNA, peptides, polypeptides, or protein, by recombinant DNA technique
|
|
DE3546806C2
(enExample)
|
1985-03-30 |
1991-03-28 |
Marc Genf/Geneve Ch Ballivet |
|
|
SE448277B
(sv)
|
1985-04-12 |
1987-02-09 |
Draco Ab |
Indikeringsanordning vid en doseringsanordning for lekemedel
|
|
US4676980A
(en)
|
1985-09-23 |
1987-06-30 |
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
Target specific cross-linked heteroantibodies
|
|
US5618920A
(en)
|
1985-11-01 |
1997-04-08 |
Xoma Corporation |
Modular assembly of antibody genes, antibodies prepared thereby and use
|
|
US5576195A
(en)
|
1985-11-01 |
1996-11-19 |
Xoma Corporation |
Vectors with pectate lyase signal sequence
|
|
DE3600905A1
(de)
|
1986-01-15 |
1987-07-16 |
Ant Nachrichtentech |
Verfahren zum dekodieren von binaersignalen sowie viterbi-dekoder und anwendungen
|
|
SE453566B
(sv)
|
1986-03-07 |
1988-02-15 |
Draco Ab |
Anordning vid pulverinhalatorer
|
|
GB8607679D0
(en)
|
1986-03-27 |
1986-04-30 |
Winter G P |
Recombinant dna product
|
|
US5225539A
(en)
|
1986-03-27 |
1993-07-06 |
Medical Research Council |
Recombinant altered antibodies and methods of making altered antibodies
|
|
EP0271581B1
(en)
|
1986-04-17 |
1993-01-13 |
Kyowa Hakko Kogyo Co., Ltd. |
Novel compounds dc-88a and dc-89a1 and process for their preparation
|
|
US5260203A
(en)
|
1986-09-02 |
1993-11-09 |
Enzon, Inc. |
Single polypeptide chain binding molecules
|
|
US4946778A
(en)
|
1987-09-21 |
1990-08-07 |
Genex Corporation |
Single polypeptide chain binding molecules
|
|
US4704692A
(en)
|
1986-09-02 |
1987-11-03 |
Ladner Robert C |
Computer based system and method for determining and displaying possible chemical structures for converting double- or multiple-chain polypeptides to single-chain polypeptides
|
|
US6893625B1
(en)
|
1986-10-27 |
2005-05-17 |
Royalty Pharma Finance Trust |
Chimeric antibody with specificity to human B cell surface antigen
|
|
IL85035A0
(en)
|
1987-01-08 |
1988-06-30 |
Int Genetic Eng |
Polynucleotide molecule,a chimeric antibody with specificity for human b cell surface antigen,a process for the preparation and methods utilizing the same
|
|
EP0832981A1
(en)
|
1987-02-17 |
1998-04-01 |
Pharming B.V. |
DNA sequences to target proteins to the mammary gland for efficient secretion
|
|
EP0307434B2
(en)
|
1987-03-18 |
1998-07-29 |
Scotgen Biopharmaceuticals, Inc. |
Altered antibodies
|
|
US4873316A
(en)
|
1987-06-23 |
1989-10-10 |
Biogen, Inc. |
Isolation of exogenous recombinant proteins from the milk of transgenic mammals
|
|
US4975278A
(en)
|
1988-02-26 |
1990-12-04 |
Bristol-Myers Company |
Antibody-enzyme conjugates in combination with prodrugs for the delivery of cytotoxic agents to tumor cells
|
|
US4939666A
(en)
|
1987-09-02 |
1990-07-03 |
Genex Corporation |
Incremental macromolecule construction methods
|
|
US5677425A
(en)
|
1987-09-04 |
1997-10-14 |
Celltech Therapeutics Limited |
Recombinant antibody
|
|
US5053394A
(en)
|
1988-09-21 |
1991-10-01 |
American Cyanamid Company |
Targeted forms of methyltrithio antitumor agents
|
|
US4994578A
(en)
|
1987-11-27 |
1991-02-19 |
Meiji Seika Kaisha, Ltd. |
Certain anti-tumor duocarmycin antibiotics from streptomyces
|
|
HUT53672A
(en)
|
1988-02-25 |
1990-11-28 |
Gen Hospital Corp |
Quick immunoselective cloning process
|
|
US5506126A
(en)
|
1988-02-25 |
1996-04-09 |
The General Hospital Corporation |
Rapid immunoselection cloning method
|
|
IL89489A0
(en)
|
1988-03-09 |
1989-09-10 |
Hybritech Inc |
Chimeric antibodies directed against human carcinoembryonic antigen
|
|
US4861579A
(en)
|
1988-03-17 |
1989-08-29 |
American Cyanamid Company |
Suppression of B-lymphocytes in mammals by administration of anti-B-lymphocyte antibodies
|
|
US6010902A
(en)
|
1988-04-04 |
2000-01-04 |
Bristol-Meyers Squibb Company |
Antibody heteroconjugates and bispecific antibodies for use in regulation of lymphocyte activity
|
|
AU631545B2
(en)
|
1988-04-15 |
1992-12-03 |
Protein Design Labs, Inc. |
Il-2 receptor-specific chimeric antibodies
|
|
JP3105898B2
(ja)
|
1988-04-16 |
2000-11-06 |
セルテック リミテッド |
組換えｄｎａタンパクの製造方法
|
|
US4925648A
(en)
|
1988-07-29 |
1990-05-15 |
Immunomedics, Inc. |
Detection and treatment of infectious and inflammatory lesions
|
|
US5601819A
(en)
|
1988-08-11 |
1997-02-11 |
The General Hospital Corporation |
Bispecific antibodies for selective immune regulation and for selective immune cell binding
|
|
US5223409A
(en)
|
1988-09-02 |
1993-06-29 |
Protein Engineering Corp. |
Directed evolution of novel binding proteins
|
|
GB8823869D0
(en)
|
1988-10-12 |
1988-11-16 |
Medical Res Council |
Production of antibodies
|
|
US5076973A
(en)
|
1988-10-24 |
1991-12-31 |
Arizona Board Of Regents |
Synthesis of dolastatin 3
|
|
GB8827305D0
(en)
|
1988-11-23 |
1988-12-29 |
British Bio Technology |
Compounds
|
|
US5530101A
(en)
|
1988-12-28 |
1996-06-25 |
Protein Design Labs, Inc. |
Humanized immunoglobulins
|
|
US4978744A
(en)
|
1989-01-27 |
1990-12-18 |
Arizona Board Of Regents |
Synthesis of dolastatin 10
|
|
DE3909708A1
(de)
|
1989-03-23 |
1990-09-27 |
Boehringer Mannheim Gmbh |
Verfahren zur herstellung bispezifischer antikoerper
|
|
CA2016841C
(en)
|
1989-05-16 |
1999-09-21 |
William D. Huse |
A method for producing polymers having a preselected activity
|
|
US4879278A
(en)
|
1989-05-16 |
1989-11-07 |
Arizona Board Of Regents |
Isolation and structural elucidation of the cytostatic linear depsipeptide dolastatin 15
|
|
CA2057923A1
(en)
|
1989-05-16 |
1990-11-17 |
William D. Huse |
Co-expression of heteromeric receptors
|
|
CA2016842A1
(en)
|
1989-05-16 |
1990-11-16 |
Richard A. Lerner |
Method for tapping the immunological repertoire
|
|
US6291158B1
(en)
|
1989-05-16 |
2001-09-18 |
Scripps Research Institute |
Method for tapping the immunological repertoire
|
|
US4986988A
(en)
|
1989-05-18 |
1991-01-22 |
Arizona Board Of Regents |
Isolation and structural elucidation of the cytostatic linear depsipeptides dolastatin 13 and dehydrodolastatin 13
|
|
DE3920358A1
(de)
|
1989-06-22 |
1991-01-17 |
Behringwerke Ag |
Bispezifische und oligospezifische, mono- und oligovalente antikoerperkonstrukte, ihre herstellung und verwendung
|
|
DE69029036T2
(de)
|
1989-06-29 |
1997-05-22 |
Medarex Inc |
Bispezifische reagenzien für die aids-therapie
|
|
CA2067194C
(en)
|
1989-10-05 |
2003-03-18 |
Glenn Kawasaki |
Cell-free synthesis and isolation of novel genes and polypeptides
|
|
US5208020A
(en)
|
1989-10-25 |
1993-05-04 |
Immunogen Inc. |
Cytotoxic agents comprising maytansinoids and their therapeutic use
|
|
US5138036A
(en)
|
1989-11-13 |
1992-08-11 |
Arizona Board Of Regents Acting On Behalf Of Arizona State University |
Isolation and structural elucidation of the cytostatic cyclodepsipeptide dolastatin 14
|
|
EP1690935A3
(en)
|
1990-01-12 |
2008-07-30 |
Abgenix, Inc. |
Generation of xenogeneic antibodies
|
|
TW212184B
(enExample)
|
1990-04-02 |
1993-09-01 |
Takeda Pharm Industry Co Ltd |
|
|
US5427908A
(en)
|
1990-05-01 |
1995-06-27 |
Affymax Technologies N.V. |
Recombinant library screening methods
|
|
EP0600866B1
(en)
|
1990-06-01 |
1997-12-03 |
Chiron Corporation |
Compositions and methods for identifying biologically active molecules
|
|
US5723286A
(en)
|
1990-06-20 |
1998-03-03 |
Affymax Technologies N.V. |
Peptide library and screening systems
|
|
EP0547065B1
(en)
|
1990-06-29 |
2001-08-29 |
Large Scale Biology Corporation |
Melanin production by transformed microorganisms
|
|
JP2938569B2
(ja)
|
1990-08-29 |
1999-08-23 |
ジェンファーム インターナショナル，インコーポレイティド |
異種免疫グロブリンを作る方法及びトランスジェニックマウス
|
|
US5770429A
(en)
|
1990-08-29 |
1998-06-23 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
|
US5789650A
(en)
|
1990-08-29 |
1998-08-04 |
Genpharm International, Inc. |
Transgenic non-human animals for producing heterologous antibodies
|
|
US5545806A
(en)
|
1990-08-29 |
1996-08-13 |
Genpharm International, Inc. |
Ransgenic non-human animals for producing heterologous antibodies
|
|
US5625126A
(en)
|
1990-08-29 |
1997-04-29 |
Genpharm International, Inc. |
Transgenic non-human animals for producing heterologous antibodies
|
|
US5661016A
(en)
|
1990-08-29 |
1997-08-26 |
Genpharm International Inc. |
Transgenic non-human animals capable of producing heterologous antibodies of various isotypes
|
|
US6300129B1
(en)
|
1990-08-29 |
2001-10-09 |
Genpharm International |
Transgenic non-human animals for producing heterologous antibodies
|
|
US5633425A
(en)
|
1990-08-29 |
1997-05-27 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
|
WO1992005258A1
(en)
|
1990-09-20 |
1992-04-02 |
La Trobe University |
Gene encoding barley enzyme
|
|
ATE160379T1
(de)
|
1990-10-29 |
1997-12-15 |
Chiron Corp |
Bispezifische antikörper, verfahren zu ihrer herstellung und deren verwendungen
|
|
WO1992009690A2
(en)
|
1990-12-03 |
1992-06-11 |
Genentech, Inc. |
Enrichment method for variant proteins with altered binding properties
|
|
US5582996A
(en)
|
1990-12-04 |
1996-12-10 |
The Wistar Institute Of Anatomy & Biology |
Bifunctional antibodies and method of preparing same
|
|
AU1435492A
(en)
|
1991-02-21 |
1992-09-15 |
Gilead Sciences, Inc. |
Aptamer specific for biomolecules and method of making
|
|
US5404871A
(en)
|
1991-03-05 |
1995-04-11 |
Aradigm |
Delivery of aerosol medications for inspiration
|
|
US20070298040A1
(en)
|
1991-03-18 |
2007-12-27 |
Centocor, Inc. |
Methods of treating seronegative arthropathy with anti-TNF antibodies
|
|
US6284471B1
(en)
|
1991-03-18 |
2001-09-04 |
New York University Medical Center |
Anti-TNFa antibodies and assays employing anti-TNFa antibodies
|
|
DK0511011T3
(da)
|
1991-04-26 |
1997-03-10 |
Surface Active Ltd |
Nye antistoffer og fremgangsmåde til anvendelse heraf
|
|
JPH06507398A
(ja)
|
1991-05-14 |
1994-08-25 |
リプリジェン コーポレーション |
Ｈｉｖ感染治療のための異種複合抗体
|
|
US6797492B2
(en)
*
|
1991-05-17 |
2004-09-28 |
Merck & Co., Inc. |
Method for reducing the immunogenicity of antibody variable domains
|
|
DE4118120A1
(de)
|
1991-06-03 |
1992-12-10 |
Behringwerke Ag |
Tetravalente bispezifische rezeptoren, ihre herstellung und verwendung
|
|
CA2103059C
(en)
|
1991-06-14 |
2005-03-22 |
Paul J. Carter |
Method for making humanized antibodies
|
|
US5637481A
(en)
|
1993-02-01 |
1997-06-10 |
Bristol-Myers Squibb Company |
Expression vectors encoding bispecific fusion proteins and methods of producing biologically active bispecific fusion proteins in a mammalian cell
|
|
ES2284226T3
(es)
|
1991-07-02 |
2007-11-01 |
Nektar Therapeutics |
Dispositivo para proporcionar medicamentos en aerosol.
|
|
US5270170A
(en)
|
1991-10-16 |
1993-12-14 |
Affymax Technologies N.V. |
Peptide library and screening method
|
|
WO1993008829A1
(en)
|
1991-11-04 |
1993-05-13 |
The Regents Of The University Of California |
Compositions that mediate killing of hiv-infected cells
|
|
EP1136556B1
(en)
|
1991-11-25 |
2005-06-08 |
Enzon, Inc. |
Method of producing multivalent antigen-binding proteins
|
|
US5932448A
(en)
|
1991-11-29 |
1999-08-03 |
Protein Design Labs., Inc. |
Bispecific antibody heterodimers
|
|
WO1993011236A1
(en)
|
1991-12-02 |
1993-06-10 |
Medical Research Council |
Production of anti-self antibodies from antibody segment repertoires and displayed on phage
|
|
WO1993011794A1
(en)
|
1991-12-13 |
1993-06-24 |
Xoma Corporation |
Methods and materials for preparation of modified antibody variable domains and therapeutic uses thereof
|
|
EP1997894B1
(en)
|
1992-02-06 |
2011-03-30 |
Novartis Vaccines and Diagnostics, Inc. |
Biosynthetic binding protein for cancer marker
|
|
AU3737893A
(en)
|
1992-03-05 |
1993-10-05 |
Board Of Regents, The University Of Texas System |
Diagnostic and/or therapeutic agents, targeted to neovascular endothelial cells
|
|
DE4207475A1
(de)
|
1992-03-10 |
1993-09-16 |
Goldwell Ag |
Mittel zum blondieren von menschlichen haaren und verfahren zu dessen herstellung
|
|
DE69231123T2
(de)
|
1992-03-25 |
2001-02-15 |
Immunogen Inc |
Konjugaten von Zell-bindender Mittel und Derivaten von CC-1065
|
|
AU4025193A
(en)
|
1992-04-08 |
1993-11-18 |
Cetus Oncology Corporation |
Humanized C-erbB-2 specific antibodies
|
|
ZA932522B
(en)
|
1992-04-10 |
1993-12-20 |
Res Dev Foundation |
Immunotoxins directed against c-erbB-2(HER/neu) related surface antigens
|
|
CA2118508A1
(en)
|
1992-04-24 |
1993-11-11 |
Elizabeth S. Ward |
Recombinant production of immunoglobulin-like domains in prokaryotic cells
|
|
CA2140280A1
(en)
|
1992-08-17 |
1994-03-03 |
Avi J. Ashkenazi |
Bispecific immunoadhesins
|
|
US5639641A
(en)
|
1992-09-09 |
1997-06-17 |
Immunogen Inc. |
Resurfacing of rodent antibodies
|
|
AU4829593A
(en)
|
1992-09-23 |
1994-04-12 |
Fisons Plc |
Inhalation device
|
|
WO1994008038A1
(en)
|
1992-10-02 |
1994-04-14 |
Trustees Of Dartmouth College |
Bispecific reagents for redirected targeting of low density lipoprotein
|
|
WO1994008552A2
(en)
|
1992-10-19 |
1994-04-28 |
Dura Pharmaceuticals, Inc. |
Dry powder inhaler
|
|
US5648267A
(en)
|
1992-11-13 |
1997-07-15 |
Idec Pharmaceuticals Corporation |
Impaired dominant selectable marker sequence and intronic insertion strategies for enhancement of expression of gene product and expression vector systems comprising same
|
|
EP0669986B1
(en)
|
1992-11-13 |
2003-04-09 |
Idec Pharmaceuticals Corporation |
Fully impaired consensus kozac sequences for mammalian expression
|
|
US7744877B2
(en)
|
1992-11-13 |
2010-06-29 |
Biogen Idec Inc. |
Expression and use of anti-CD20 Antibodies
|
|
US5736137A
(en)
|
1992-11-13 |
1998-04-07 |
Idec Pharmaceuticals Corporation |
Therapeutic application of chimeric and radiolabeled antibodies to human B lymphocyte restricted differentiation antigen for treatment of B cell lymphoma
|
|
PT752248E
(pt)
|
1992-11-13 |
2001-01-31 |
Idec Pharma Corp |
Aplicacao terapeutica de anticorpos quimericos e marcados radioactivamente contra antigenios de diferenciacao restrita de linfocitos b humanos para o tratamento do linfoma de celulas b
|
|
WO1994012520A1
(en)
|
1992-11-20 |
1994-06-09 |
Enzon, Inc. |
Linker for linked fusion polypeptides
|
|
US6034065A
(en)
|
1992-12-03 |
2000-03-07 |
Arizona Board Of Regents |
Elucidation and synthesis of antineoplastic tetrapeptide phenethylamides of dolastatin 10
|
|
US5455258A
(en)
|
1993-01-06 |
1995-10-03 |
Ciba-Geigy Corporation |
Arylsulfonamido-substituted hydroxamic acids
|
|
US5849695A
(en)
|
1993-01-13 |
1998-12-15 |
The Regents Of The University Of California |
Parathyroid hormone analogues useful for treatment of osteoporosis and disorders of calcium meatabolism in mammals
|
|
DE69414369T2
(de)
|
1993-01-19 |
1999-05-27 |
Glaxo Group Ltd., Greenford, Middlesex |
Aerosol-spender und verfahren zu seiner herstellung
|
|
US5770428A
(en)
|
1993-02-17 |
1998-06-23 |
Wisconsin Alumni Research Foundation |
Chimeric retrovial expression vectors and particles containing a simple retroviral long terminal repeat, BLV or HIV coding regions and cis-acting regulatory sequences, and an RNA translational enhancer with internal ribsome entry site
|
|
CA2161351C
(en)
|
1993-04-26 |
2010-12-21 |
Nils Lonberg |
Transgenic non-human animals capable of producing heterologous antibodies
|
|
US5885573A
(en)
|
1993-06-01 |
1999-03-23 |
Arch Development Corporation |
Methods and materials for modulation of the immunosuppressive activity and toxicity of monoclonal antibodies
|
|
WO1994029351A2
(en)
|
1993-06-16 |
1994-12-22 |
Celltech Limited |
Antibodies
|
|
US5417972A
(en)
|
1993-08-02 |
1995-05-23 |
The Board Of Trustees Of The Leland Stanford Junior University |
Method of killing B-cells in a complement independent and an ADCC independent manner using antibodies which specifically bind CDIM
|
|
US5514670A
(en)
|
1993-08-13 |
1996-05-07 |
Pharmos Corporation |
Submicron emulsions for delivery of peptides
|
|
US5595721A
(en)
|
1993-09-16 |
1997-01-21 |
Coulter Pharmaceutical, Inc. |
Radioimmunotherapy of lymphoma using anti-CD20
|
|
US5432930A
(en)
|
1993-09-30 |
1995-07-11 |
Eagle Crest Limited |
System for accessing cobol data files by generating a dictionary of NF.sup.2
|
|
US5625825A
(en)
|
1993-10-21 |
1997-04-29 |
Lsi Logic Corporation |
Random number generating apparatus for an interface unit of a carrier sense with multiple access and collision detect (CSMA/CD) ethernet data network
|
|
DE4337197C1
(de)
|
1993-10-30 |
1994-08-25 |
Biotest Pharma Gmbh |
Verfahren zur selektiven Herstellung von Hybridomazellinien, die monoklonale Antikörper mit hoher Zytotoxizität gegen humanes CD16-Antigen produzieren, sowie Herstellung bispezifischer monoklonaler Antikörper unter Verwendung derartiger monoklonaler Antikörper und des CD30-HRS-3-Antikörpers zur Therapie menschlicher Tumore
|
|
US5814599A
(en)
|
1995-08-04 |
1998-09-29 |
Massachusetts Insitiute Of Technology |
Transdermal delivery of encapsulated drugs
|
|
FR2713447B1
(fr)
|
1993-12-15 |
1996-02-09 |
Chenier Ste Civile |
Procédé et installation de torréfaction de fruits du genre noix de cajou ou analogues.
|
|
US5827690A
(en)
|
1993-12-20 |
1998-10-27 |
Genzyme Transgenics Corporatiion |
Transgenic production of antibodies in milk
|
|
US5837458A
(en)
|
1994-02-17 |
1998-11-17 |
Maxygen, Inc. |
Methods and compositions for cellular and metabolic engineering
|
|
US5605793A
(en)
|
1994-02-17 |
1997-02-25 |
Affymax Technologies N.V. |
Methods for in vitro recombination
|
|
US5834252A
(en)
|
1995-04-18 |
1998-11-10 |
Glaxo Group Limited |
End-complementary polymerase reaction
|
|
ES2178669T3
(es)
|
1994-03-07 |
2003-01-01 |
Medarex Inc |
Moleculas biespecificas que tienen utilidad clinica.
|
|
US5436361A
(en)
|
1994-04-22 |
1995-07-25 |
Clemson University |
Process for synthesizing enediynes
|
|
DE4415998A1
(de)
|
1994-05-06 |
1995-11-09 |
Basf Ag |
Neue Tetrapeptide, ihre Herstellung Verwendung
|
|
JPH07309761A
(ja)
|
1994-05-20 |
1995-11-28 |
Kyowa Hakko Kogyo Co Ltd |
デュオカルマイシン誘導体の安定化法
|
|
DE69534530T2
(de)
|
1994-08-12 |
2006-07-06 |
Immunomedics, Inc. |
Für b-zell-lymphom und leukämiezellen spezifische immunkonjugate und humane antikörper
|
|
US5554725A
(en)
|
1994-09-14 |
1996-09-10 |
Arizona Board Of Regents Acting On Behalf Of Arizona State University |
Synthesis of dolastatin 15
|
|
US5763733A
(en)
|
1994-10-13 |
1998-06-09 |
Enzon, Inc. |
Antigen-binding fusion proteins
|
|
JPH08175990A
(ja)
|
1994-12-19 |
1996-07-09 |
Mitsubishi Chem Corp |
Ｐｉ３キナーゼ阻害剤とその製造法
|
|
JPH08176070A
(ja)
|
1994-12-19 |
1996-07-09 |
Mitsubishi Chem Corp |
ジデプシド誘導体及びｐｉ３キナーゼ阻害剤
|
|
US5549551A
(en)
|
1994-12-22 |
1996-08-27 |
Advanced Cardiovascular Systems, Inc. |
Adjustable length balloon catheter
|
|
US5731168A
(en)
|
1995-03-01 |
1998-03-24 |
Genentech, Inc. |
Method for making heteromultimeric polypeptides
|
|
US5863949A
(en)
|
1995-03-08 |
1999-01-26 |
Pfizer Inc |
Arylsulfonylamino hydroxamic acid derivatives
|
|
US6037453A
(en)
|
1995-03-15 |
2000-03-14 |
Genentech, Inc. |
Immunoglobulin variants
|
|
US5656730A
(en)
|
1995-04-07 |
1997-08-12 |
Enzon, Inc. |
Stabilized monomeric protein compositions
|
|
US6121022A
(en)
|
1995-04-14 |
2000-09-19 |
Genentech, Inc. |
Altered polypeptides with increased half-life
|
|
US5869046A
(en)
|
1995-04-14 |
1999-02-09 |
Genentech, Inc. |
Altered polypeptides with increased half-life
|
|
MX9708026A
(es)
|
1995-04-20 |
1997-11-29 |
Pfizer |
Derivados del acido arislfulfonil hidroxamico, composiciones que los contienen y uso de los mismos.
|
|
EP0823941A4
(en)
|
1995-04-28 |
2001-09-19 |
Abgenix Inc |
HUMAN ANTIBODIES DERIVED FROM IMMUNIZED XENO MOUSES
|
|
US6410690B1
(en)
|
1995-06-07 |
2002-06-25 |
Medarex, Inc. |
Therapeutic compounds comprised of anti-Fc receptor antibodies
|
|
DE19526926A1
(de)
|
1995-07-24 |
1997-01-30 |
Bayer Ag |
Verfahren zur Herstellung beladener nichtporöser Trägermaterialien
|
|
GB9521987D0
(en)
|
1995-10-26 |
1996-01-03 |
Ludwig Inst Cancer Res |
Phosphoinositide 3-kinase modulators
|
|
GB9624482D0
(en)
|
1995-12-18 |
1997-01-15 |
Zeneca Phaema S A |
Chemical compounds
|
|
GB9526100D0
(en)
|
1995-12-20 |
1996-02-21 |
Intersurgical Ltd |
Nebulizer
|
|
ES2183905T3
(es)
|
1995-12-20 |
2003-04-01 |
Hoffmann La Roche |
Inhibidores de metaloproteasa de matriz.
|
|
PL327616A1
(en)
|
1996-01-03 |
1998-12-21 |
Glaxo Group Ltd |
Inhaler
|
|
KR19990082463A
(ko)
|
1996-02-13 |
1999-11-25 |
돈 리사 로얄 |
혈관 내피 성장 인자 억제제로서의 퀴나졸린유도체
|
|
GB9603256D0
(en)
|
1996-02-16 |
1996-04-17 |
Wellcome Found |
Antibodies
|
|
AU719327B2
(en)
|
1996-03-05 |
2000-05-04 |
Astrazeneca Ab |
4-anilinoquinazoline derivatives
|
|
US5714352A
(en)
|
1996-03-20 |
1998-02-03 |
Xenotech Incorporated |
Directed switch-mediated DNA recombination
|
|
DE19624387C2
(de)
|
1996-06-19 |
1999-08-19 |
Hatz Motoren |
Kaltstartvorrichtung
|
|
EP0818442A3
(en)
|
1996-07-12 |
1998-12-30 |
Pfizer Inc. |
Cyclic sulphone derivatives as inhibitors of metalloproteinases and of the production of tumour necrosis factor
|
|
IL127567A0
(en)
|
1996-07-18 |
1999-10-28 |
Pfizer |
Phosphinate based inhibitors of matrix metalloproteases
|
|
US20010056066A1
(en)
|
1996-07-26 |
2001-12-27 |
Smithkline Beecham Corporation |
Method of treating immune cell mediated systemic diseases
|
|
JP2000501423A
(ja)
|
1996-08-23 |
2000-02-08 |
ファイザー インク． |
アリールスルホニルアミノヒドロキサム酸誘導体
|
|
ATE210682T1
(de)
|
1996-09-03 |
2001-12-15 |
Gsf Forschungszentrum Umwelt |
Zerstörung von kontaminierenden tumorzellen in stammzelltransplantaten mit bispezifischen antikörpern
|
|
JPH1087666A
(ja)
|
1996-09-18 |
1998-04-07 |
Kyorin Pharmaceut Co Ltd |
デュオカルマイシンｓａ及びその誘導体の製造中間体と製造方法
|
|
GB9718972D0
(en)
|
1996-09-25 |
1997-11-12 |
Zeneca Ltd |
Chemical compounds
|
|
ES2301183T3
(es)
|
1996-12-03 |
2008-06-16 |
Amgen Fremont Inc. |
Anticuerpo completamente humano que se une al receptor del egfr.
|
|
PT950059E
(pt)
|
1997-01-06 |
2004-10-29 |
Pfizer |
Derivados de sulfona ciclicos
|
|
ES2202796T3
(es)
|
1997-02-03 |
2004-04-01 |
Pfizer Products Inc. |
Derivados de acidos arilsulfonilaminohidroxamicos.
|
|
EP0966438A1
(en)
|
1997-02-07 |
1999-12-29 |
Pfizer Inc. |
N-hydroxy-beta-sulfonyl-propionamide derivatives and their use as inhibitors of matrix metalloproteinases
|
|
CA2280151C
(en)
|
1997-02-11 |
2005-12-13 |
Pfizer Inc. |
Arylsulfonyl hydroxamic acid derivatives
|
|
DE69837529T2
(de)
|
1997-02-12 |
2007-07-26 |
Electrophoretics Ltd., Cobham |
Proteinmarker für lungenkrebs und deren verwendung
|
|
US5921447A
(en)
|
1997-02-13 |
1999-07-13 |
Glaxo Wellcome Inc. |
Flow-through metered aerosol dispensing apparatus and method of use thereof
|
|
CA2282504A1
(en)
|
1997-02-25 |
1998-08-27 |
Jun-Ping Xu |
Isolation and structural elucidation of the cytostatic linear and cyclo-depsipeptides dolastatin 16, dolastatin 17, and dolastatin 18
|
|
US6277375B1
(en)
|
1997-03-03 |
2001-08-21 |
Board Of Regents, The University Of Texas System |
Immunoglobulin-like domains with increased half-lives
|
|
US5965537A
(en)
|
1997-03-10 |
1999-10-12 |
Basf Aktiengesellschaft |
Dolastatin 15 derivatives with carbonyl and heterocyclic functionalities at the C-terminus
|
|
US6103698A
(en)
|
1997-03-13 |
2000-08-15 |
Basf Aktiengesellschaft |
Dolastatin-15 derivatives in combination with taxanes
|
|
US6306393B1
(en)
|
1997-03-24 |
2001-10-23 |
Immunomedics, Inc. |
Immunotherapy of B-cell malignancies using anti-CD22 antibodies
|
|
US6183744B1
(en)
|
1997-03-24 |
2001-02-06 |
Immunomedics, Inc. |
Immunotherapy of B-cell malignancies using anti-CD22 antibodies
|
|
US6235883B1
(en)
|
1997-05-05 |
2001-05-22 |
Abgenix, Inc. |
Human monoclonal antibodies to epidermal growth factor receptor
|
|
DE69825048D1
(de)
|
1997-05-22 |
2004-08-19 |
Scripps Research Inst |
Analoga von duocarmycin and cc-1065
|
|
US6171586B1
(en)
|
1997-06-13 |
2001-01-09 |
Genentech, Inc. |
Antibody formulation
|
|
US6991790B1
(en)
|
1997-06-13 |
2006-01-31 |
Genentech, Inc. |
Antibody formulation
|
|
EP0999853B1
(en)
|
1997-06-13 |
2003-01-02 |
Genentech, Inc. |
Stabilized antibody formulation
|
|
JP2002506353A
(ja)
|
1997-06-24 |
2002-02-26 |
ジェネンテック・インコーポレーテッド |
ガラクトシル化糖タンパク質の方法及び組成物
|
|
US20040191256A1
(en)
|
1997-06-24 |
2004-09-30 |
Genentech, Inc. |
Methods and compositions for galactosylated glycoproteins
|
|
AU8296098A
(en)
|
1997-07-08 |
1999-02-08 |
Board Of Regents, The University Of Texas System |
Compositions and methods for homoconjugates of antibodies which induce growth arrest or apoptosis of tumor cells
|
|
US6143721A
(en)
|
1997-07-18 |
2000-11-07 |
Basf Aktiengesellschaft |
Dolastatin 15 derivatives
|
|
EA002490B1
(ru)
|
1997-08-08 |
2002-06-27 |
Пфайзер Продактс Инк. |
Производные арилоксиарилсульфониламиногидроксамовой кислоты
|
|
US6686445B1
(en)
|
1997-09-24 |
2004-02-03 |
Arizona Board Of Regents, Acting For And On Behalf Of Arizona State University |
Synthetic antineoplastic agents derived from dolastatin 15 and methods of making same
|
|
GB9722131D0
(en)
|
1997-10-20 |
1997-12-17 |
Medical Res Council |
Method
|
|
WO1999022764A1
(en)
|
1997-10-31 |
1999-05-14 |
Genentech, Inc. |
Methods and compositions comprising glycoprotein glycoforms
|
|
GB9725782D0
(en)
|
1997-12-05 |
1998-02-04 |
Pfizer Ltd |
Therapeutic agents
|
|
GB9801690D0
(en)
|
1998-01-27 |
1998-03-25 |
Pfizer Ltd |
Therapeutic agents
|
|
JP4462654B2
(ja)
|
1998-03-26 |
2010-05-12 |
ソニー株式会社 |
映像素材選択装置及び映像素材選択方法
|
|
DK1068241T3
(da)
|
1998-04-02 |
2008-02-04 |
Genentech Inc |
Antistofvarianter og fragmenter deraf
|
|
US6194551B1
(en)
|
1998-04-02 |
2001-02-27 |
Genentech, Inc. |
Polypeptide variants
|
|
US6242195B1
(en)
|
1998-04-02 |
2001-06-05 |
Genentech, Inc. |
Methods for determining binding of an analyte to a receptor
|
|
US6528624B1
(en)
|
1998-04-02 |
2003-03-04 |
Genentech, Inc. |
Polypeptide variants
|
|
PA8469501A1
(es)
|
1998-04-10 |
2000-09-29 |
Pfizer Prod Inc |
Hidroxamidas del acido (4-arilsulfonilamino)-tetrahidropiran-4-carboxilico
|
|
PA8469401A1
(es)
|
1998-04-10 |
2000-05-24 |
Pfizer Prod Inc |
Derivados biciclicos del acido hidroxamico
|
|
PT1071700E
(pt)
|
1998-04-20 |
2010-04-23 |
Glycart Biotechnology Ag |
Modificação por glicosilação de anticorpos para melhorar a citotoxicidade celular dependente de anticorpos
|
|
GB9809951D0
(en)
|
1998-05-08 |
1998-07-08 |
Univ Cambridge Tech |
Binding molecules
|
|
US5985837A
(en)
|
1998-07-08 |
1999-11-16 |
Basf Aktiengesellschaft |
Dolastatin 15 derivatives
|
|
DE69939939D1
(de)
|
1998-08-11 |
2009-01-02 |
Idec Pharma Corp |
Kombinationstherapien gegen b-zell-lymphome beinhaltend die verabreichung von anti-cd20-antikörpern
|
|
US6224866B1
(en)
|
1998-10-07 |
2001-05-01 |
Biocrystal Ltd. |
Immunotherapy of B cell involvement in progression of solid, nonlymphoid tumors
|
|
DE69915004T2
(de)
|
1998-11-05 |
2004-09-09 |
Pfizer Products Inc., Groton |
5-Oxo-pyrrolidine-2-Carbonsäure-Hydroxamidderivate
|
|
TR200101302T2
(tr)
|
1998-11-09 |
2001-10-22 |
Idec Pharmaceuticals Corporation |
BMT yada PBSC transplantı alan hastalarda in vitro ya da in vivo temizleyici madde olarak kimerik anti-CD20 antikorunun kullanımı.
|
|
ES2351149T3
(es)
|
1998-11-09 |
2011-02-01 |
Biogen Idec Inc. |
Anticuerpo quimérico dirigido contra cd20, el rituxan, para uso en el tratamiento de la leucemia linfocítica crónica.
|
|
ES2694002T3
(es)
|
1999-01-15 |
2018-12-17 |
Genentech, Inc. |
Polipéptido que comprende una región Fc de IgG1 humana variante
|
|
US6737056B1
(en)
|
1999-01-15 |
2004-05-18 |
Genentech, Inc. |
Polypeptide variants with altered effector function
|
|
US6897044B1
(en)
|
1999-01-28 |
2005-05-24 |
Biogen Idec, Inc. |
Production of tetravalent antibodies
|
|
SK288365B6
(sk)
|
1999-02-10 |
2016-07-01 |
Astrazeneca Ab |
Medziprodukty pre chinazolínové deriváty ako inhibítory angiogenézy
|
|
WO2000061739A1
(fr)
|
1999-04-09 |
2000-10-19 |
Kyowa Hakko Kogyo Co., Ltd. |
Methode de regulation de l'activite d'une molecule immunologiquement fonctionnelle
|
|
IL146005A0
(en)
|
1999-05-07 |
2002-07-25 |
Genentech Inc |
Treatment of autoimmune diseases with antagonists which bind to b cell surface markers
|
|
KR20020020730A
(ko)
|
1999-06-09 |
2002-03-15 |
오트리브 데이비스 더블유 |
Ｂ-세포를 표적하는 항체를 이용한 자가면역질환의 면역치료
|
|
ITMI991299A1
(it)
|
1999-06-11 |
2000-12-11 |
Consiglio Nazionale Ricerche |
Uso di anticorpi contro antigeni di superficie per il trattamento della malattia trapianto contro ospite
|
|
DE19930748C2
(de)
|
1999-07-02 |
2001-05-17 |
Infineon Technologies Ag |
Verfahren zur Herstellung von EEPROM- und DRAM-Grabenspeicherzellbereichen auf einem Chip
|
|
KR20020027490A
(ko)
|
1999-07-12 |
2002-04-13 |
제넨테크, 인크. |
Ｃｄ20에 결합하는 길항제를 사용한 외래 항원에 대한면역 반응 차단 방법
|
|
US6451284B1
(en)
|
1999-08-11 |
2002-09-17 |
Idec Pharmaceuticals Corporation |
Clinical parameters for determining hematologic toxicity prior to radioimmunotheraphy
|
|
US8557244B1
(en)
|
1999-08-11 |
2013-10-15 |
Biogen Idec Inc. |
Treatment of aggressive non-Hodgkins lymphoma with anti-CD20 antibody
|
|
JP2003513012A
(ja)
|
1999-08-11 |
2003-04-08 |
アイデック ファーマスーティカルズ コーポレイション |
抗ｃｄ２０抗体による骨髄病変を伴う非ホジキンリンパ腫を有する患者の治療
|
|
AU6929100A
(en)
|
1999-08-23 |
2001-03-19 |
Biocrystal Limited |
Methods and compositions for immunotherapy of b cell involvement in promotion ofa disease condition comprising multiple sclerosis
|
|
US6323315B1
(en)
|
1999-09-10 |
2001-11-27 |
Basf Aktiengesellschaft |
Dolastatin peptides
|
|
US20030044420A1
(en)
|
1999-09-24 |
2003-03-06 |
Mccormick Alison A. |
Self antigen vaccines for treating B cell lymphomas and other cancers
|
|
WO2001024763A2
(en)
|
1999-10-01 |
2001-04-12 |
Immunogen, Inc. |
Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents
|
|
US7504256B1
(en)
|
1999-10-19 |
2009-03-17 |
Kyowa Hakko Kogyo Co., Ltd. |
Process for producing polypeptide
|
|
IL149034A0
(en)
|
1999-11-05 |
2002-11-10 |
Astrazeneca Ab |
Quinazoline derivatives as vegf inhibitors
|
|
US20020028178A1
(en)
|
2000-07-12 |
2002-03-07 |
Nabil Hanna |
Treatment of B cell malignancies using combination of B cell depleting antibody and immune modulating antibody related applications
|
|
US20020006404A1
(en)
|
1999-11-08 |
2002-01-17 |
Idec Pharmaceuticals Corporation |
Treatment of cell malignancies using combination of B cell depleting antibody and immune modulating antibody related applications
|
|
KR20020072277A
(ko)
|
1999-11-08 |
2002-09-14 |
아이덱 파마슈티칼즈 코포레이션 |
항-ｃｄ20 항체 및/또는 화학요법 및 방사선요법과결합하여 항-ｃｄ40ｌ 항체를 이용한 ｂ세포 악성종양의치료방법
|
|
JP2003514903A
(ja)
|
1999-11-24 |
2003-04-22 |
イムノージェン インコーポレーテッド |
タキサンを含有する細胞傷害薬とその治療への利用
|
|
CN1406249B
(zh)
|
2000-02-11 |
2010-06-16 |
默克专利股份有限公司 |
增加基于抗体的融合蛋白的循环半衰期
|
|
RS50444B
(sr)
|
2000-02-15 |
2010-03-02 |
Sugen Inc. |
Inhibitori 2-indolinon protein kinaze supstituisani pirolom
|
|
JP2001247477A
(ja)
|
2000-03-03 |
2001-09-11 |
Teikoku Hormone Mfg Co Ltd |
抗腫瘍剤
|
|
US7097840B2
(en)
|
2000-03-16 |
2006-08-29 |
Genentech, Inc. |
Methods of treatment using anti-ErbB antibody-maytansinoid conjugates
|
|
US20030185796A1
(en)
|
2000-03-24 |
2003-10-02 |
Chiron Corporation |
Methods of therapy for non-hodgkin's lymphoma
|
|
WO2001072333A1
(en)
|
2000-03-24 |
2001-10-04 |
Chiron Corporation |
Methods of therapy for non-hodgkin's lymphoma using a combination_of an antibody to cd20 and interleuking-2
|
|
CN1981868A
(zh)
|
2000-03-31 |
2007-06-20 |
拜奥根Idec公司 |
抗细胞因子抗体或拮抗剂与抗－cd20在b细胞淋巴瘤治疗中的联合应用
|
|
PT2857516T
(pt)
|
2000-04-11 |
2017-08-28 |
Genentech Inc |
Anticorpos multivalentes e utilizações dos mesmos
|
|
US7416726B2
(en)
|
2000-04-13 |
2008-08-26 |
The Rockefeller University |
Enhancement of antibody-mediated immune responses
|
|
CA2405632A1
(en)
|
2000-04-25 |
2001-11-01 |
Idec Pharmaceutical Corporation |
Intrathecal administration of rituximab for treatment of central nervous system lymphomas
|
|
US6608053B2
(en)
|
2000-04-27 |
2003-08-19 |
Yamanouchi Pharmaceutical Co., Ltd. |
Fused heteroaryl derivatives
|
|
US6403588B1
(en)
|
2000-04-27 |
2002-06-11 |
Yamanouchi Pharmaceutical Co., Ltd. |
Imidazopyridine derivatives
|
|
JP2004512262A
(ja)
|
2000-06-20 |
2004-04-22 |
アイデック ファーマスーティカルズ コーポレイション |
非放射性抗ｃｄ２０抗体／放射標識抗ｃｄ２２抗体の組合せ
|
|
DE60139689D1
(de)
|
2000-06-22 |
2009-10-08 |
Univ Iowa Res Found |
Kombination von CpG und Antikörpern gegen CD19,CD20,CD22 oder CD40 zur Prävention oder Behandlung von Krebs.
|
|
CA2415100A1
(en)
|
2000-07-12 |
2002-01-17 |
Idec Pharmaceutical Corporation |
Treatment of b cell malignancies using combination of b cell depleting antibody and immune modulating antibody related applications
|
|
US6725230B2
(en)
|
2000-07-18 |
2004-04-20 |
Aegis Analytical Corporation |
System, method and computer program for assembling process data of multi-database origins using a hierarchical display
|
|
US6333410B1
(en)
|
2000-08-18 |
2001-12-25 |
Immunogen, Inc. |
Process for the preparation and purification of thiol-containing maytansinoids
|
|
AR030612A1
(es)
|
2000-09-12 |
2003-08-27 |
Smithkline Beecham Corp |
Procedimiento e intermedios
|
|
KR20040023565A
(ko)
|
2000-09-18 |
2004-03-18 |
아이덱 파마슈티칼즈 코포레이션 |
Ｂ 세포 고갈/면역조절 항체 조합을 이용한 자가면역질환의 치료를 위한 조합 요법
|
|
US6946292B2
(en)
|
2000-10-06 |
2005-09-20 |
Kyowa Hakko Kogyo Co., Ltd. |
Cells producing antibody compositions with increased antibody dependent cytotoxic activity
|
|
EP1333032A4
(en)
|
2000-10-06 |
2005-03-16 |
Kyowa Hakko Kogyo Kk |
PROCESS FOR PURIFYING ANTIBODY
|
|
US7064191B2
(en)
|
2000-10-06 |
2006-06-20 |
Kyowa Hakko Kogyo Co., Ltd. |
Process for purifying antibody
|
|
MXPA03002974A
(es)
|
2000-10-06 |
2004-05-05 |
Kyowa Hakko Kogyo Kk |
Celulas que producen composiciones de anticuerpo.
|
|
WO2002034790A1
(en)
|
2000-10-20 |
2002-05-02 |
Idec Pharmaceuticals Corporation |
Variant igg3 rituxan r and therapeutic use thereof
|
|
ES2649037T3
(es)
|
2000-12-12 |
2018-01-09 |
Medimmune, Llc |
Moléculas con semividas prolongadas, composiciones y usos de las mismas
|
|
EP2325205A3
(en)
|
2000-12-28 |
2011-10-12 |
Altus Pharmaceuticals Inc. |
Crystals of whole antibodies and fragments thereof and methods for making and using them
|
|
DE60203260T2
(de)
|
2001-01-16 |
2006-02-02 |
Glaxo Group Ltd., Greenford |
Pharmazeutische kombination, die ein 4-chinazolinamin und paclitaxel, carboplatin oder vinorelbin enthält, zur behandlung von krebs
|
|
US7754208B2
(en)
|
2001-01-17 |
2010-07-13 |
Trubion Pharmaceuticals, Inc. |
Binding domain-immunoglobulin fusion proteins
|
|
US7829084B2
(en)
|
2001-01-17 |
2010-11-09 |
Trubion Pharmaceuticals, Inc. |
Binding constructs and methods for use thereof
|
|
CN1911965B
(zh)
|
2001-01-17 |
2013-05-29 |
新兴产品开发西雅图有限公司 |
结合域-免疫球蛋白融合蛋白
|
|
US20030133939A1
(en)
|
2001-01-17 |
2003-07-17 |
Genecraft, Inc. |
Binding domain-immunoglobulin fusion proteins
|
|
WO2002096948A2
(en)
|
2001-01-29 |
2002-12-05 |
Idec Pharmaceuticals Corporation |
Engineered tetravalent antibodies and methods of use
|
|
KR20030091978A
(ko)
|
2001-01-29 |
2003-12-03 |
아이덱 파마슈티칼즈 코포레이션 |
변형된 항체 및 사용 방법
|
|
US20030103971A1
(en)
|
2001-11-09 |
2003-06-05 |
Kandasamy Hariharan |
Immunoregulatory antibodies and uses thereof
|
|
US6444163B1
(en)
|
2001-03-06 |
2002-09-03 |
Kawasaki Steel Corporation |
Heat shielding apparatus for vertical continuous annealing furnace
|
|
US20020156274A1
(en)
|
2001-03-16 |
2002-10-24 |
Terfloth Gerald J. |
Process for preparing maytansinol
|
|
AU2002307037B2
(en)
|
2001-04-02 |
2008-08-07 |
Biogen Idec Inc. |
Recombinant antibodies coexpressed with GnTIII
|
|
EP2359849A1
(en)
|
2001-04-02 |
2011-08-24 |
Genentech, Inc. |
Combination therapy
|
|
ITPD20010108A1
(it)
|
2001-05-08 |
2002-11-08 |
Fidia Advanced Biopolymers Srl |
Biomateriali polimerici elettricamente conduttori, loro processo di preparazione ed impiego nel settore biomedico sanitario.
|
|
WO2003061694A1
(en)
|
2001-05-10 |
2003-07-31 |
Seattle Genetics, Inc. |
Immunosuppression of the humoral immune response by anti-cd20 antibodies
|
|
US6441163B1
(en)
|
2001-05-31 |
2002-08-27 |
Immunogen, Inc. |
Methods for preparation of cytotoxic conjugates of maytansinoids and cell binding agents
|
|
EP1404366A4
(en)
|
2001-06-14 |
2006-06-07 |
Intermune Inc |
COMBINED THERAPY USING INTERFERON GAMMA AND SPECIFIC B-CELL ANTIBODIES
|
|
US7321026B2
(en)
|
2001-06-27 |
2008-01-22 |
Skytech Technology Limited |
Framework-patched immunoglobulins
|
|
US6737409B2
(en)
|
2001-07-19 |
2004-05-18 |
Hoffmann-La Roche Inc. |
Dolastatin 10 derivatives
|
|
CA2454976C
(en)
|
2001-07-26 |
2011-05-10 |
Santen Pharmaceutical Co., Ltd. |
Therapeutic agent for glaucoma comprising compound having pi3 kinase inhibitory action as active ingredient
|
|
CA2838062C
(en)
|
2001-08-03 |
2015-12-22 |
Roche Glycart Ag |
Antibody glycosylation variants having increased antibody-dependent cellular cytotoxicity
|
|
US6703414B2
(en)
|
2001-09-14 |
2004-03-09 |
Arizona Board Of Regents On Behalf Of The University Of Arizona |
Device and method for treating restenosis
|
|
DE60233744D1
(de)
|
2001-09-20 |
2009-10-29 |
Univ Texas |
Bestimmung der zirkulierenden therapeutischen antikörper, antigene sowie antigen-antikörper-komplexe mit elisa-tests
|
|
WO2003034997A2
(en)
|
2001-10-24 |
2003-05-01 |
Iconix Pharmaceuticals, Inc. |
Modulators of phosphoinositide 3-kinase
|
|
AU2002349912A1
(en)
|
2001-10-24 |
2003-05-06 |
Iconix Pharmaceuticals, Inc. |
Modulators of phosphoinositide 3-kinase
|
|
NZ532526A
(en)
|
2001-10-25 |
2007-01-26 |
Genentech Inc |
Compositions comprising a glycoprotein having a Fc region
|
|
JP2005509645A
(ja)
|
2001-10-30 |
2005-04-14 |
ファルマシア・コーポレーション |
炎症処置用のヘテロ芳香族カルボキサミド誘導体
|
|
CN1210307C
(zh)
|
2001-11-16 |
2005-07-13 |
上海中信国健药业有限公司 |
抗cd20人源化单克隆抗体
|
|
WO2003045312A2
(en)
|
2001-11-21 |
2003-06-05 |
University Of Washington |
Biosynthetic gene cluster for the maytansinoid antitumor agent ansamitocin
|
|
CA2469045A1
(en)
|
2001-12-07 |
2003-06-19 |
Chiron Corporation |
Methods of therapy for non-hodgkin's lymphoma
|
|
US6716821B2
(en)
|
2001-12-21 |
2004-04-06 |
Immunogen Inc. |
Cytotoxic agents bearing a reactive polyethylene glycol moiety, cytotoxic conjugates comprising polyethylene glycol linking groups, and methods of making and using the same
|
|
US20040093621A1
(en)
*
|
2001-12-25 |
2004-05-13 |
Kyowa Hakko Kogyo Co., Ltd |
Antibody composition which specifically binds to CD20
|
|
US6790954B2
(en)
|
2002-01-29 |
2004-09-14 |
Immunogen, Inc. |
Mutant Actinosynnema pretiosum strain with increased maytansinoid production
|
|
KR101033196B1
(ko)
|
2002-02-14 |
2011-05-09 |
이뮤노메딕스, 인코오포레이티드 |
항-ｃｄ20 항체 및 그 융합 단백질 및 이들의 이용방법
|
|
US20040002587A1
(en)
|
2002-02-20 |
2004-01-01 |
Watkins Jeffry D. |
Fc region variants
|
|
US7317091B2
(en)
|
2002-03-01 |
2008-01-08 |
Xencor, Inc. |
Optimized Fc variants
|
|
US20040132101A1
(en)
|
2002-09-27 |
2004-07-08 |
Xencor |
Optimized Fc variants and methods for their generation
|
|
WO2003074679A2
(en)
|
2002-03-01 |
2003-09-12 |
Xencor |
Antibody optimization
|
|
US20030180292A1
(en)
|
2002-03-14 |
2003-09-25 |
Idec Pharmaceuticals |
Treatment of B cell malignancies using anti-CD40L antibodies in combination with anti-CD20 antibodies and/or chemotherapeutics and radiotherapy
|
|
US6756397B2
(en)
|
2002-04-05 |
2004-06-29 |
Immunogen, Inc. |
Prodrugs of CC-1065 analogs
|
|
WO2003084569A1
(en)
|
2002-04-09 |
2003-10-16 |
Kyowa Hakko Kogyo Co., Ltd. |
Drug containing antibody composition
|
|
MXPA04009924A
(es)
|
2002-04-09 |
2005-07-01 |
Kyowa Hakko Kogyo Kk |
Celulas de genoma modificado.
|
|
JPWO2003085118A1
(ja)
|
2002-04-09 |
2005-08-11 |
協和醗酵工業株式会社 |
抗体組成物の製造方法
|
|
AU2003236019A1
(en)
|
2002-04-09 |
2003-10-20 |
Kyowa Hakko Kirin Co., Ltd. |
Drug containing antibody composition appropriate for patient suffering from Fc Gamma RIIIa polymorphism
|
|
JP4628679B2
(ja)
|
2002-04-09 |
2011-02-09 |
協和発酵キリン株式会社 |
Ｇｄｐ−フコースの輸送に関与する蛋白質の活性が低下または欠失した細胞
|
|
US20040259150A1
(en)
|
2002-04-09 |
2004-12-23 |
Kyowa Hakko Kogyo Co., Ltd. |
Method of enhancing of binding activity of antibody composition to Fcgamma receptor IIIa
|
|
US20030219818A1
(en)
|
2002-05-10 |
2003-11-27 |
Bohen Sean P. |
Methods and compositions for determining neoplastic disease responsiveness to antibody therapy
|
|
WO2003096782A2
(en)
|
2002-05-13 |
2003-11-27 |
Smithkline Beecham Corporation |
Process for preparing maytansinol
|
|
US6596757B1
(en)
|
2002-05-14 |
2003-07-22 |
Immunogen Inc. |
Cytotoxic agents comprising polyethylene glycol-containing taxanes and their therapeutic use
|
|
US7538195B2
(en)
|
2002-06-14 |
2009-05-26 |
Immunogen Inc. |
Anti-IGF-I receptor antibody
|
|
DE60305919T2
(de)
|
2002-06-28 |
2007-01-18 |
Domantis Limited, Cambridge |
Dual-specifische liganden mit erhöhter halbwertszeit
|
|
US20040092561A1
(en)
|
2002-11-07 |
2004-05-13 |
Thomas Ruckle |
Azolidinone-vinyl fused -benzene derivatives
|
|
WO2004006916A1
(en)
|
2002-07-10 |
2004-01-22 |
Applied Research Systems Ars Holding Nv |
Use of compounds for increasing spermatozoa motility
|
|
MXPA05000453A
(es)
|
2002-07-10 |
2005-03-23 |
Applied Research Systems |
Derivados de benceno fusionados a azolidinona-vinilo.
|
|
US20050180972A1
(en)
|
2002-07-31 |
2005-08-18 |
Wahl Alan F. |
Anti-CD20 antibody-drug conjugates for the treatment of cancer and immune disorders
|
|
JP2005539009A
(ja)
|
2002-08-02 |
2005-12-22 |
イミュノジェン・インコーポレーテッド |
新規の効力のあるタキサンを含む細胞毒性物質、および、それらの治療用途
|
|
JP4459810B2
(ja)
|
2002-08-14 |
2010-04-28 |
マクロジェニクス，インコーポレーテッド |
ＦｃγＲＩＩＢ特異的抗体とその利用法
|
|
ATE499116T1
(de)
|
2002-08-16 |
2011-03-15 |
Immunogen Inc |
Vernetzer mit hoher reaktivität und löslichkeit und ihre verwendung bei der herstellung von konjugaten für die gezielte abgabe von kleinmolekularen arzneimitteln
|
|
EP1391213A1
(en)
|
2002-08-21 |
2004-02-25 |
Boehringer Ingelheim International GmbH |
Compositions and methods for treating cancer using maytansinoid CD44 antibody immunoconjugates and chemotherapeutic agents
|
|
WO2004017950A2
(en)
|
2002-08-22 |
2004-03-04 |
Piramed Limited |
Phosphadidylinositol 3,5-biphosphate inhibitors as anti-viral agents
|
|
EP3321282A1
(en)
|
2002-09-27 |
2018-05-16 |
Xencor, Inc. |
Optimized fc variants and methods for their generation
|
|
JP4768439B2
(ja)
|
2002-10-15 |
2011-09-07 |
アボット バイオセラピューティクス コーポレイション |
変異誘発による抗体のＦｃＲｎ結合親和力又は血清半減期の改変
|
|
PT1558648E
(pt)
*
|
2002-10-17 |
2012-04-23 |
Genmab As |
Anticorpos monoclonais humanos contra cd20
|
|
US20040120949A1
(en)
|
2002-11-08 |
2004-06-24 |
Boehringer Ingelheim International Gmbh |
Compositions and methods for treating cancer using cytotoxic CD44 antibody immunoconjugates and radiotherapy
|
|
JP4480128B2
(ja)
|
2002-11-20 |
2010-06-16 |
独立行政法人科学技術振興機構 |
マトリックスメタロプロテアーゼ−９の産生を阻害するための薬剤
|
|
AR042485A1
(es)
|
2002-12-16 |
2005-06-22 |
Genentech Inc |
Anticuerpo humanizado que se une al cd20 humano
|
|
KR20050084317A
(ko)
|
2002-12-16 |
2005-08-26 |
제넨테크, 인크. |
인간 ｃｄ２０ 및(또는) ｃｄ１６을 발현하는 트랜스제닉마우스
|
|
EP1578801A2
(en)
|
2002-12-27 |
2005-09-28 |
Domantis Limited |
Dual specific single domain antibodies specific for a ligand and for the receptor of the ligand
|
|
US7534427B2
(en)
|
2002-12-31 |
2009-05-19 |
Immunomedics, Inc. |
Immunotherapy of B cell malignancies and autoimmune diseases using unconjugated antibodies and conjugated antibodies and antibody combinations and fusion proteins
|
|
JP2006524039A
(ja)
|
2003-01-09 |
2006-10-26 |
マクロジェニクス，インコーポレーテッド |
変異型Ｆｃ領域を含む抗体の同定および作製ならびにその利用法
|
|
WO2004076489A1
(en)
|
2003-02-25 |
2004-09-10 |
Medinnova As |
Modified antibody
|
|
US8084582B2
(en)
|
2003-03-03 |
2011-12-27 |
Xencor, Inc. |
Optimized anti-CD20 monoclonal antibodies having Fc variants
|
|
MXPA05010778A
(es)
|
2003-04-09 |
2005-12-12 |
Genentech Inc |
Terapia para enfermedad autoinmune en un paciente con una respuesta inadecuada a un inhibidor tnf-alfa.
|
|
US7755007B2
(en)
|
2003-04-17 |
2010-07-13 |
K&H Manufacturing, Inc |
Heated pet mat
|
|
CA2522637C
(en)
|
2003-04-17 |
2014-01-21 |
Alnylam Pharmaceuticals, Inc. |
Modified irna agents
|
|
KR101412271B1
(ko)
|
2003-05-09 |
2014-06-25 |
듀크 유니버시티 |
Ｃｄ２０-특이적 항체 및 이를 이용한 방법
|
|
MX342007B
(es)
|
2003-05-14 |
2016-09-09 |
Immunogen Inc |
Composicion de farmaco conjugado.
|
|
US8088387B2
(en)
|
2003-10-10 |
2012-01-03 |
Immunogen Inc. |
Method of targeting specific cell populations using cell-binding agent maytansinoid conjugates linked via a non-cleavable linker, said conjugates, and methods of making said conjugates
|
|
US7276497B2
(en)
|
2003-05-20 |
2007-10-02 |
Immunogen Inc. |
Cytotoxic agents comprising new maytansinoids
|
|
AR044388A1
(es)
|
2003-05-20 |
2005-09-07 |
Applied Molecular Evolution |
Moleculas de union a cd20
|
|
NZ543712A
(en)
|
2003-06-05 |
2008-06-30 |
Genentech Inc |
Combination therapy for B cell disorders
|
|
US20050163775A1
(en)
|
2003-06-05 |
2005-07-28 |
Genentech, Inc. |
Combination therapy for B cell disorders
|
|
US7834155B2
(en)
|
2003-07-21 |
2010-11-16 |
Immunogen Inc. |
CA6 antigen-specific cytotoxic conjugate and methods of using the same
|
|
HRP20110302T1
(hr)
|
2003-07-21 |
2011-06-30 |
Immunogen |
Ca6 antigen-specifični citotoksični konjugat i postupci za njegovu uporabu
|
|
WO2005011428A1
(en)
|
2003-07-25 |
2005-02-10 |
Bally Gaming International, Inc. |
Uniquely identifiable casino gaming chips
|
|
WO2005017529A1
(en)
|
2003-07-29 |
2005-02-24 |
Genentech, Inc. |
Assay for human anti cd20 antibodies and uses therefor
|
|
WO2005014618A2
(en)
|
2003-08-08 |
2005-02-17 |
Immunomedics, Inc. |
Bispecific antibodies for inducing apoptosis of tumor and diseased cells
|
|
US8147832B2
(en)
|
2003-08-14 |
2012-04-03 |
Merck Patent Gmbh |
CD20-binding polypeptide compositions and methods
|
|
JP2007504138A
(ja)
|
2003-08-29 |
2007-03-01 |
ジェネンテック・インコーポレーテッド |
眼疾患の治療法
|
|
US7288396B2
(en)
|
2003-09-11 |
2007-10-30 |
Kosan Biosciences Incorporated |
Biosynthetic gene cluster for leptomycins
|
|
AU2004279742A1
(en)
|
2003-10-08 |
2005-04-21 |
Kyowa Hakko Kirin Co., Ltd. |
Fused protein composition
|
|
AU2004280065A1
(en)
|
2003-10-09 |
2005-04-21 |
Kyowa Hakko Kirin Co., Ltd. |
Process for producing antibody composition by using RNA inhibiting the function of alpha1,6-fucosyltransferase
|
|
GB0324368D0
(en)
|
2003-10-17 |
2003-11-19 |
Univ Cambridge Tech |
Polypeptides including modified constant regions
|
|
TR201809892T4
(tr)
|
2003-11-05 |
2018-07-23 |
Roche Glycart Ag |
Fc reseptörüne bağlanma afinitesi ve artırılmış efektör fonksiyonu bulunan antijen bağlayan moleküller.
|
|
GB0325952D0
(en)
|
2003-11-06 |
2003-12-10 |
Du Pont |
Method for producing enhanced solid state polymerization of polyethylene terephthalate
|
|
WO2005053742A1
(ja)
|
2003-12-04 |
2005-06-16 |
Kyowa Hakko Kogyo Co., Ltd. |
抗体組成物を含有する医薬
|
|
AU2004303848A1
(en)
|
2003-12-19 |
2005-07-07 |
Genentech, Inc. |
Detection of CD20 in transplant rejection
|
|
EP1696955A2
(en)
|
2003-12-19 |
2006-09-06 |
Genentech, Inc. |
Detection of cd20 in therapy of autoimmune diseases
|
|
ATE437184T1
(de)
|
2004-01-12 |
2009-08-15 |
Applied Molecular Evolution |
Varianten der fc-region
|
|
WO2005067980A2
(en)
|
2004-01-12 |
2005-07-28 |
Pointilliste, Inc. |
Design of therapeutics and therapeutics
|
|
US20050203174A1
(en)
|
2004-03-09 |
2005-09-15 |
Kosan Biosciences, Inc. |
Combination therapies using leptomycin B
|
|
WO2005099754A2
(en)
|
2004-04-14 |
2005-10-27 |
The Ohio State University Research Foundation |
Maytansinoid analogs as antitumor agents
|
|
BRPI0509419A
(pt)
|
2004-04-16 |
2007-09-04 |
Genentech Inc |
método de ensaio imunossorvente ligado por enzimas, anticorpos, hibridoma e kit de imunoensaio
|
|
AU2005244751A1
(en)
|
2004-04-16 |
2005-12-01 |
Genentech, Inc. |
Method for augmenting B cell depletion
|
|
EP1742660A2
(en)
|
2004-04-16 |
2007-01-17 |
Genentech, Inc. |
Treatment of disorders
|
|
US7850962B2
(en)
|
2004-04-20 |
2010-12-14 |
Genmab A/S |
Human monoclonal antibodies against CD20
|
|
CN1980697A
(zh)
|
2004-05-05 |
2007-06-13 |
健泰科生物技术公司 |
通过使用抗cd20抗体预防自身免疫病
|
|
WO2005114218A2
(en)
|
2004-05-15 |
2005-12-01 |
Genentech, Inc. |
Cross-screening system and methods for detecting a molecule having binding affinity for a target molecule
|
|
CA2567520A1
(en)
|
2004-06-01 |
2005-12-15 |
Genentech, Inc. |
Maytansinoid-antibody conjugates
|
|
US7446196B2
(en)
|
2004-06-03 |
2008-11-04 |
Kosan Biosciences, Incorporated |
Leptomycin compounds
|
|
AR049292A1
(es)
|
2004-06-04 |
2006-07-12 |
Genentech Inc |
Metodo para tratar lupus con un anticuerpo cd20
|
|
AU2005249566B2
(en)
|
2004-06-04 |
2010-11-11 |
Genentech, Inc. |
Method for treating multiple sclerosis
|
|
JP2008505148A
(ja)
|
2004-07-09 |
2008-02-21 |
バイエル・シエーリング・ファーマ アクチエンゲゼルシャフト |
Ｂ細胞リンパ腫の治療における放射線標識化抗ｃｄ２０抗体を使用する組合わせ治療
|
|
DK2471813T3
(en)
|
2004-07-15 |
2015-03-02 |
Xencor Inc |
Optimized Fc variants
|
|
EP1781378A2
(en)
|
2004-07-22 |
2007-05-09 |
Genentech, Inc. |
Method of treating sjögren's syndrome
|
|
KR20070057839A
(ko)
|
2004-08-19 |
2007-06-07 |
제넨테크, 인크. |
변경된 이펙터 기능을 갖는 폴리펩티드 변이체
|
|
BRPI0515615A
(pt)
|
2004-09-08 |
2008-07-29 |
Genentech Inc |
métodos para tratar células cancerosas e doença imune relacionada
|
|
ZA200702335B
(en)
|
2004-10-05 |
2009-05-27 |
Genentech Inc |
Method for treating vasculitis
|
|
TW200630106A
(en)
|
2004-10-08 |
2006-09-01 |
Wyeth Corp |
Immunotherapy of autoimmune disorders
|
|
WO2006047350A2
(en)
|
2004-10-21 |
2006-05-04 |
Xencor, Inc. |
IgG IMMUNOGLOBULIN VARIANTS WITH OPTIMIZED EFFECTOR FUNCTION
|
|
GB0423653D0
(en)
|
2004-10-25 |
2004-11-24 |
Piramed Ltd |
Pharmaceutical compounds
|
|
US20060099235A1
(en)
|
2004-11-11 |
2006-05-11 |
Medtronic Vascular, Inc. |
Medical devices and compositions useful for treating or inhibiting restenosis
|
|
EP1688415A1
(en)
|
2004-12-07 |
2006-08-09 |
Aventis Pharma S.A. |
Cytotoxic agents comprising new C-2 modified taxanes
|
|
KR101281501B1
(ko)
|
2004-12-09 |
2013-07-15 |
얀센 바이오테크 인코포레이티드 |
항인테그린 면역 컨쥬게이트, 방법 및 용도
|
|
WO2006063706A1
(en)
|
2004-12-13 |
2006-06-22 |
F. Hoffmann-La Roche Ag |
Novel process for the manufacture of 3-pyrrolidin-2-yl-propionic acid derivatives
|
|
FR2879204B1
(fr)
|
2004-12-15 |
2007-02-16 |
Lab Francais Du Fractionnement |
Anticorps cytotoxique dirige contre les proliferations hematopoietiques lymphoides de type b.
|
|
RU2007126970A
(ru)
|
2004-12-17 |
2009-01-27 |
Джинентех, Инк. (US) |
Антиагиогенная терапия аутоиммунного заболевания у пациентов, предшествующее лечение которых не дало результата
|
|
JP2008525041A
(ja)
|
2004-12-22 |
2008-07-17 |
ジェネンテック・インコーポレーテッド |
可溶性多膜貫通型タンパク質の産生方法
|
|
US20060188495A1
(en)
|
2005-01-13 |
2006-08-24 |
Genentech, Inc. |
Treatment method
|
|
CN101102993A
(zh)
|
2005-01-13 |
2008-01-09 |
霍夫曼-拉罗奇有限公司 |
有用的双取代胺类的新型一步合成
|
|
US7301019B2
(en)
|
2005-01-21 |
2007-11-27 |
Immunogen, Inc. |
Method for the preparation of maytansinoid esters
|
|
DOP2006000029A
(es)
|
2005-02-07 |
2006-08-15 |
Genentech Inc |
Antibody variants and uses thereof. (variantes de un anticuerpo y usos de las mismas)
|
|
WO2006086733A2
(en)
|
2005-02-11 |
2006-08-17 |
Immunogen, Inc. |
Process for preparing maytansinoid antibody conjugates
|
|
US20060280738A1
(en)
|
2005-06-08 |
2006-12-14 |
Tedder Thomas F |
Anti-CD19 antibody therapy for transplantation
|
|
TW200714289A
(en)
|
2005-02-28 |
2007-04-16 |
Genentech Inc |
Treatment of bone disorders
|
|
DE602006019565D1
(de)
|
2005-03-31 |
2011-02-24 |
Biomedics Inc |
Monoklonaler anti-cd20-antikörper
|
|
ES2359854T3
(es)
*
|
2005-03-31 |
2011-05-27 |
Biomedics Inc. |
Anticuerpo monoclonal anti-cd20.
|
|
CA2602663A1
(en)
|
2005-03-31 |
2006-10-05 |
Xencor, Inc. |
Fc variants with optimized properties
|
|
EP1868649A4
(en)
|
2005-04-15 |
2011-06-29 |
Immunogen Inc |
ELIMINATION OF A POPULATION OF HETEROGENEOUS OR MIXED CELLS IN TUMORS
|
|
JP2009508467A
(ja)
|
2005-05-24 |
2009-03-05 |
アベスタゲン リミテッド |
Ｂ細胞リンパ腫の治療のためのｃｄ２０に対するモノクローナル抗体を生成する方法
|
|
ZA200710496B
(en)
|
2005-06-02 |
2009-04-29 |
Astrazeneca Ab |
Antibodies directed to CD20 and used thereof
|
|
CN1290864C
(zh)
|
2005-07-11 |
2006-12-20 |
中国人民解放军军事医学科学院生物工程研究所 |
一种抗cd20嵌合抗体
|
|
EA014513B1
(ru)
|
2005-08-03 |
2010-12-30 |
Иммьюноджен, Инк. |
Композиция иммуноконъюгата
|
|
US20070213292A1
(en)
|
2005-08-10 |
2007-09-13 |
The Rockefeller University |
Chemically modified oligonucleotides for use in modulating micro RNA and uses thereof
|
|
NZ595430A
(en)
|
2005-08-24 |
2013-05-31 |
Immunogen Inc |
Process for preparing maytansinoid antibody conjugates
|
|
EP1931709B1
(en)
|
2005-10-03 |
2016-12-07 |
Xencor, Inc. |
Fc variants with optimized fc receptor binding properties
|
|
GB0520657D0
(en)
|
2005-10-11 |
2005-11-16 |
Ludwig Inst Cancer Res |
Pharmaceutical compounds
|
|
GB0525214D0
(en)
*
|
2005-12-12 |
2006-01-18 |
Bioinvent Int Ab |
Biological materials and uses thereof
|
|
US7441063B2
(en)
|
2005-12-14 |
2008-10-21 |
Aten International Co., Ltd. |
KVM system for controlling computers and method thereof
|
|
PT1813614E
(pt)
|
2006-01-25 |
2012-01-09 |
Sanofi Sa |
Agentes citotóxicos compreendendo novos derivados de tomaimicina
|
|
SG170750A1
(en)
|
2006-03-17 |
2011-05-30 |
Biogen Idec Inc |
Stabilized polypeptide compositions
|
|
EP1864682A1
(en)
|
2006-06-09 |
2007-12-12 |
Sanofi-Aventis |
Leptomycin derivatives
|
|
US20080003652A1
(en)
|
2006-06-28 |
2008-01-03 |
Hans Iding |
Novel enzymatic process for the manufacture of Boc-Dap-Oh priority to related application(s)
|
|
US20130004480A1
(en)
|
2006-07-04 |
2013-01-03 |
Paul Parren |
CD20 Binding Molecules for the Treatment of Copd
|
|
US7846434B2
(en)
|
2006-10-24 |
2010-12-07 |
Trubion Pharmaceuticals, Inc. |
Materials and methods for improved immunoglycoproteins
|
|
PE20090321A1
(es)
|
2007-06-04 |
2009-04-20 |
Genentech Inc |
Anticuerpos anti-notch1 nrr, metodo de preparacion y composicion farmaceutica
|
|
CA2691322A1
(en)
*
|
2007-06-12 |
2008-12-24 |
Wyeth |
Anti-cd20 therapeutic compositions and methods
|
|
DK2019104T3
(da)
|
2007-07-19 |
2013-12-16 |
Sanofi Sa |
Cytotoksiske midler, der omfatter nye tomaymycinderivater, og terapeutisk anvendelse deraf
|
|
GB0714602D0
(en)
|
2007-07-26 |
2007-09-05 |
Novathera Ltd |
Process
|
|
US20110243931A1
(en)
*
|
2007-09-02 |
2011-10-06 |
Thomas Friess |
Combination therapy with type i and type ii anti-cd20 antibodies
|
|
JP5470817B2
(ja)
|
2008-03-10 |
2014-04-16 |
日産自動車株式会社 |
電池用電極およびこれを用いた電池、並びにその製造方法
|
|
CN104524592B
(zh)
|
2008-04-30 |
2018-06-05 |
伊缪诺金公司 |
交联剂和它们的用途
|
|
WO2011100398A1
(en)
|
2010-02-10 |
2011-08-18 |
Immunogen, Inc. |
Cd20 antibodies and uses thereof
|
|
JP6136279B2
(ja)
|
2013-01-15 |
2017-05-31 |
株式会社ジェイテクト |
転がり軸受装置
|
|
TWI503850B
(zh)
|
2013-03-22 |
2015-10-11 |
Polytronics Technology Corp |
過電流保護元件
|
|
TWI510996B
(zh)
|
2013-10-03 |
2015-12-01 |
Acer Inc |
控制觸控面板的方法以及使用該方法的可攜式電腦
|
|
US9816280B1
(en)
|
2016-11-02 |
2017-11-14 |
Matthew Reitnauer |
Portable floor
|
|
US11392902B2
(en)
|
2017-06-06 |
2022-07-19 |
United Parcel Service Of America, Inc. |
Systems, methods, apparatuses and computer program products for providing notification of items for pickup and delivery
|